Florian Salomons

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: EMBO JOURNAL. 2023;42(3):e111802

Cytosolic stress granules relieve the ubiquitin-proteasome system in the nuclear compartment

Xu S; Gierisch ME; Schellhaus AK; Poser I; Alberti S; Salomons FA; Dantuma NP
Article: AUTOPHAGY. 2022;18(7):1486-1502

Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy

Giovannucci TA; Salomons FA; Stoy H; Herzog LK; Xu S; Qian W; Merino LG; Gierisch ME; Haraldsson M; Lystad AH; Uvell H; Simonsen A; Gustavsson A-L; Vallin M; Dantuma NP
Article: CELL DEATH & DISEASE. 2021;12(10):914

Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound

Giovannucci TA; Salomons FA; Haraldsson M; Elfman LHM; Wickstroem M; Young P; Lundbaeck T; Eirich J; Altun M; Jafari R; Gustavsson A-L; Johnsen JI; Dantuma NP
Article: SCIENTIFIC REPORTS. 2020;10(1):22334

K63-linked ubiquitylation induces global sequestration of mitochondria

Richard TJC; Herzog LK; Vornberger J; Rahmanto AS; Sangfelt O; Salomons FA; Dantuma NP
Article: AGING CELL. 2020;19(1):e13051

The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy

Herzog LK; Kevei E; Marchante R; Bottcher C; Bindesboll C; Lystad AH; Pfeiffer A; Gierisch ME; Salomons FA; Simonsen A; Hoppe T; Dantuma NP
Article: EMBO JOURNAL. 2017;36(8):1066-1083

Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4

Pfeiffer A; Luijsterburg MS; Acs K; Wiegant WW; Helfricht A; Herzog LK; Minoia M; Bottcher C; Salomons FA; van Attikum H; Dantuma NP
Article: SCIENTIFIC REPORTS. 2016;6:27703

The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C^Cdh1 ubiquitin ligase complex

Bott LC; Salomons FA; Maric D; Liu Y; Merry D; Fischbeck KH; Dantuma NP
Article: PLOS ONE. 2016;11(12):e0168276

Functional Analyses of the Crohn's Disease Risk Gene LACC1

Assadi G; Vesterlund L; Bonfiglio F; Mazzurana L; Cordeddu L; Schepis D; Mjosberg J; Ruhrmann S; Fabbri A; Vukojevic V; Percipalle P; Salomons FA; Laurencikiene J; Torkvist L; Halfvarson J; D'Amato M
Article: CIRCULATION RESEARCH. 2015;117(6):513-524

Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus

Raaz U; Schellinger IN; Chernogubova E; Warnecke C; Kayama Y; Penov K; Hennigs JK; Salomons F; Eken S; Emrich FC; Zheng WH; Adam M; Jagger A; Nakagami F; Toh R; Toyama K; Deng A; Buerke M; Maegdefessel L; Hasenfuss G; Spin JM; Tsao PS
Article: WOOD SCIENCE AND TECHNOLOGY. 2014;48(4):737-753

Fiber- and fine fractions-derived effects on pulp quality as a result of mechanical pulp refining consistency

Hafren J; Fernando D; Gorski D; Daniel G; Salomons FA
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2011;18(12):1345-1U55

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

Acs K; Luijsterburg MS; Ackermann L; Salomons FA; Hoppe T; Dantuma NP
Article: AUTOPHAGY. 2010;6(2):217-227

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

Tresse E; Salomons FA; Vesa J; Bott LC; Kimonis V; Yao T-P; Dantuma NP; Taylor JP
Article: JOURNAL OF MOLECULAR BIOLOGY. 2009;394(4):732-746

A Conserved Unfoldase Activity for the p97 AAA-ATPase in Proteasomal Degradation

Beskow A; Grimberg KB; Bott LC; Salomons FA; Dantuma NP; Young P
Article: MOLECULAR AND CELLULAR BIOLOGY. 2009;29(7):1774-1785

Selective Accumulation of Aggregation-Prone Proteasome Substrates in Response to Proteotoxic Stress

Salomons FA; Menendez-Benito V; Bottcher C; McCray BA; Taylor JP; Dantuma NP
Article: FASEB JOURNAL. 2009;23(1):123-133

Minimal length requirement for proteasomal degradation of ubiquitin-dependent substrates

Verhoef LGGC; Heinen C; Selivanova A; Halff EF; Salomons FA; Dantuma NP
Article: EXPERIMENTAL CELL RESEARCH. 2007;313(16):3568-3578

Modulation of polyglutamine inclusion formation by the Hsp70 chaperone machine

Rujano MA; Kampinga HH; Salomons FA
Article: PLOS BIOLOGY. 2006;4(12):e417

Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes.

Rujano MA; Bosveld F; Salomons FA; Dijk F; van Waarde MAWH; van der Want JJL; de Vos RAI; Brunt ER; Sibon OCM; Kampinga HH
Article: CELL DIVISION. 2006;1:21

Ubiquitin crosstalk connecting cellular processes

Groothuis TAM; Dantuma NP; Neefjes J; Salomons FA
Article: AUTOPHAGY. 2006;2(3):183-188

Pex14p is not required for N-starvation induced microautophagy and in catalytic amounts for macropexophagy in Hansenula polymorpha.

de Vries B; Todde V; Stevens P; Salomons F; van der Klei IJ; Veenhuis M
Article: MOLECULAR AND CELLULAR BIOLOGY. 2006;26(12):4628-4641

Cell-type-specific regulation of degradation of hypoxia-inducible factor 1α:: Role of subcellular compartmentalization

Zheng X; Ruas JL; Cao R; Salomons FA; Cao Y; Poellinger L; Pereira T
Article: GENES & DEVELOPMENT. 2006;20(10):1343-1352

DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A

Bergink S; Salomons FA; Hoogstraten D; Groothuis TAM; de Waard H; Wu J; Yuan L; Citterio E; Houtsmuller AB; Neefjes J; Hoeijmakers IHJ; Vermeulen W; Dantuma NP
Article: JOURNAL OF CELL BIOLOGY. 2006;173(1):19-26

A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling

Dantuma NP; Groothuis TAM; Salomons FA; Neefjes J
Journal article: ESSAYS IN BIOCHEMISTRY. 2005;41:113-128

Fluorescent reporters for the ubiquitin–proteasome system

Salomons FA; Verhoef LGGC; Dantuma NP
Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(14):4948-4958

Overexpression of the cochaperone CHIP enhances Hsp70-dependent folding activity in mammalian cells.

Kampinga HH; Kanon B; Salomons FA; Kabakov AE; Patterson C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(45):42875-42880

Removal of Pex3p is an important initial stage in selective peroxisome degradation in Hansenula polymorpha.

Bellu AR; Salomons FA; Kiel JAKW; Veenhuis M; Van Der Klei IJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(21):12038-12043

Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protection.

Nollen EA; Salomons FA; Brunsting JF; van der Want JJ; Sibon OC; Kampinga HH
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(6):4190-4198

Peroxisomal remnant structures in Hansenula polymorpha Pex5 cells can develop into normal peroxisomes upon induction of the PTS2 protein amine oxidase.

Salomons FA; Nico Faber K; Veenhuis M; van Der Klei IJ
Article: JOURNAL OF BACTERIOLOGY. 2000;182(24):7007-7013

The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism.

Luttik MA; Kötter P; Salomons FA; van der Klei IJ; van Dijken JP; Pronk JT
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(17):12603-12611

Overproduction of Pex5p stimulates import of alcohol oxidase and dihydroxyacetone synthase in a Hansenula polymorpha Pex14 null mutant.

Salomons FA; Kiel JA; Faber KN; Veenhuis M; van der Klei IJ
Article: YEAST. 1999;15(11):1059-1078

Hansenula polymorpha Pex1p and Pex6p are peroxisome-associated AAA proteins that functionally and physically interact.

Kiel JA; Hilbrands RE; van der Klei IJ; Rasmussen SW; Salomons FA; van der Heide M; Faber KN; Cregg JM; Veenhuis M
Article: YEAST. 1999;15(9):741-754

The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p.

Kiel JA; Rechinger KB; van der Klei IJ; Salomons FA; Titorenko VI; Veenhuis M
Article: YEAST. 1997;13(15):1449-1463

Deviant Pex3p levels affect normal peroxisome formation in Hansenula polymorpha: a sharp increase of the protein level induces the proliferation of numerous, small protein-import competent peroxisomes.

Baerends RJ; Salomons FA; Kiel JA; van der Klei IJ; Veenhuis M
Article: YEAST. 1997;13(15):1437-1448

Deviant Pex3p levels affect normal peroxisome formation in Hansenula polymorpha: high steady-state levels of the protein fully abolish matrix protein import.

Baerends RJ; Salomons FA; Faber KN; Kiel JA; Van der Klei IJ; Veenhuis M
Article: FEBS LETTERS. 1997;411(1):133-139

Brefeldin A interferes with peroxisomal protein sorting in the yeast Hansenula polymorpha.

Salomons FA; van der Klei IJ; Kram AM; Harder W; Veenhuis M
Article: FEBS LETTERS. 1996;383(1-2):114-118

Peroxisomal remnants in peroxisome-deficient mutants of the yeast Hansenula polymorpha [corrected].

Veenhuis M; Komori M; Salomons F; Hilbrands RE; Hut H; Baerends RJ; Kiel JA; van der Klei IJ
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Preprint: BIORXIV. 2021

Inhibition of the ubiquitin-proteasome system by a bioactivatable compound

Giovannucci T; Salomons F; Haraldsson M; Elfman L; Wickström M; Young P; Lundbäck T; Eirich J; Altun M; Jafari R; Gustavsson A-L; Johnsen JI; Dantuma N
Preprint: SSRN ELECTRONIC JOURNAL. 2020

Inhibition of the Ubiquitin-Proteasome System by a Bioactivatable Prodrug

Giovannucci TA; Salomons FA; Martin Haraldsson M; Elfman LMH; Wickström M; Young P; Lundbäck T; Eirich J; Altun M; Jafari R; Gustavsson A-L; Johnsen JI; Dantuma N
Editorial comment: JOURNAL OF CELL BIOLOGY. 2016;213(2):147-149

Ubiquitin versus misfolding: The minimal requirements for inclusion body formation

Dantuma NP; Salomons FA
Meeting abstract: BLOOD. 2013;122(21):3698

Granulocyte-Macrophage Progenitors (GMPs) Express Low Adhesive Potential and High CXCR-4 Levels

Giai V; Scharenberg C; Wallin R; Salomons F; Bergmann O; Conte S; Ferrero D; Boccadoro M; Hellstroem-Lindberg E
Conference publication: HAEMATOLOGICA. 2012;97:289-290

CHARACTERIZATION OF HEMATOPOIETIC STEM AND PROGENITOR CELL ADHESION TO SURROGATE MICROENVIRONMENTS

Giai V; Scharenberg C; Wallin R; Salomons F; Bergmann O; Conte S; Ferrero D; Hellstrom-Lindberg E
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1289-1295

Illuminating the ubiquitin/proteasome system

Salomons FA; Acs K; Dantuma NP
Review: ESSAYS IN BIOCHEMISTRY. 2005;41:113-128

Fluorescent reporters for the ubiquitin-proteasome system

Salomons FA; Verhoef LGGC; Dantuma NP
Review: MICROSCOPY RESEARCH AND TECHNIQUE. 2000;51(6):584-600

Peroxisome biogenesis and degradation in yeast: a structure/function analysis.

Veenhuis M; Salomons FA; Van Der Klei IJ

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