Ewoud Ewing

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: NEUROLOGY. 2023;101(7):E679-E689
Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis
Maltby V; Xavier A; Ewing E; Campagna M-P; Sampangi S; Scott RJ; Butzkueven H; Jokubaitis V; Kular L; Bos S; Slee M; van der Mei IA; Taylor BV; Ponsonby A-L; Jagodic M; Lea R; Lechner-Scott J
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(16):12576
DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes
Xavier A; Maltby VE; Ewing E; Campagna MP; Burnard SM; Tegner JN; Slee M; Butzkueven H; Kockum I; Kular L; Jokubaitis VG; Kilpatrick T; Alfredsson L; Jagodic M; Ponsonby A-L; Taylor BV; Scott RJ; Lea RA; Lechner-Scott J
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1251772
Simultaneous detection of DNA variation and methylation at HLA class II locus and immune gene promoters using targeted SureSelect Methyl-Sequencing
Kalomoiri M; Prakash CR; Lagstroem S; Hauschulz K; Ewing E; Shchetynsky K; Kular L; Needhamsen M; Jagodic M
Article: EPIGENETICS. 2022;17(11):1311-1330
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients
Kular L; Ewing E; Needhamsen M; Kakhki MP; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
Article: BIOMOLECULES. 2022;12(6):779
Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
Qu H; Heinback R; Salo H; Ewing E; Espinosa A; Aulin C; Erlandsson Harris H
Article: FRONTIERS IN AGING NEUROSCIENCE. 2022;14:926468
Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients
Kular L; Klose D; Urdanoz-Casado A; Ewing E; Planell N; Gomez-Cabrero D; Needhamsen M; Jagodic M
Article: FRONTIERS IN GENETICS. 2021;12:620453
STATegra: Multi-Omics Data Integration - A Conceptual Scheme With a Bioinformatics Pipeline
Planell N; Lagani V; Sebastian-Leon P; van der Kloet F; Ewing E; Karathanasis N; Urdangarin A; Arozarena I; Jagodic M; Tsamardinos I; Tarazona S; Conesa A; Tegner J; Gomez-Cabrero D
Article: SCIENCE IMMUNOLOGY. 2020;5(52):eabb5077
Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.
Berglund R; Guerreiro-Cacais AO; Adzemovic MZ; Zeitelhofer M; Lund H; Ewing E; Ruhrmann S; Nutma E; Parsa R; Thessen-Hedreul M; Amor S; Harris RA; Olsson T; Jagodic M
Article: BMC BIOINFORMATICS. 2020;21(1):443
GeneSetCluster: a tool for summarizing and integrating gene-set analysis results
Ewing E; Planell-Picola N; Jagodic M; Gomez-Cabrero D
Article: NATURE COMMUNICATIONS. 2020;11(1):4071
Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis
Carlstrom KE; Zhu K; Ewing E; Krabbendam IE; Harris RA; Falcao AM; Jagodic M; Castelo-Branco G; Piehl F
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2020;201:105699
Genome-wide investigation of DNA methylation in congenital adrenal hyperplasia
Karlsson L; Barbaro M; Ewing E; Gomez-Cabrero D; Lajic S
Article: SCIENTIFIC REPORTS. 2019;9(1):11996
Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients
Fernandes SJ; Morikawa H; Ewing E; Ruhrmann S; Joshi RN; Lagani V; Karathanasis N; Khademi M; Planell N; Schmidt A; Tsamardinos I; Olsson T; Piehl F; Kockum I; Jagodic M; Tegner J; Gomez-Cabrero D
Article: NATURE COMMUNICATIONS. 2019;10(1):3081
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
Carlstrom KE; Ewing E; Granqvist M; Gyllenberg A; Aeinehband S; Enoksson SL; Checa A; Badam TVS; Huang J; Gomez-Cabrero D; Gustafsson M; Al Nimer F; Wheelock CE; Kockum I; Olsson T; Jagodic M; Piehl F
Article: CLINICAL EPIGENETICS. 2019;11(1):86
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Kular L; Needhamsen M; Adzemovic MZ; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegner J; Beck S; Piehl F; Brundin L; Jagodic M
Article: EBIOMEDICINE. 2019;43:411-423
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression
Ewing E; Kular L; Fernandes SJ; Karathanasis N; Lagani V; Ruhrmann S; Tsamardinos I; Tegner J; Piehl F; Gomez-Cabrero D; Jagodic M
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2019;3(1):250-263
Epigenetic Alterations Associated With Early Prenatal Dexamethasone Treatment
Karlsson L; Barbaro M; Ewing E; Gomez-Cabrero D; Lajic S
Article: NATURE COMMUNICATIONS. 2018;9(1):4845
Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
Lund H; Pieber M; Parsa R; Han J; Grommisch D; Ewing E; Kular L; Needhamsen M; Espinosa A; Nilsson E; Overby AK; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: MULTIPLE SCLEROSIS JOURNAL. 2018;24(10):1288-1300
Hypermethylation of MIR21 in CD4+T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes
Ruhrmann S; Ewing E; Piket E; Kular L; Lorenzi JCC; Fernandes SJ; Morikawa H; Aeinehband S; Sayols-Baixeras S; Aslibekyan S; Absher DM; Arnett DK; Tegner J; Gomez-Cabrero D; Piehl F; Jagodic M
Article: NATURE COMMUNICATIONS. 2018;9(1):2397
DNA methylation as a mediator of HLA-DRB1^☆15:01 and a protective variant in multiple sclerosis
Kular L; Liu Y; Ruhrmann S; Zheleznyakova G; Marabita F; Gomez-Cabrero D; James T; Ewing E; Linden M; Gornikiewicz B; Aeinehband S; Stridh P; Link J; Andlauer TFM; Gasperi C; Wiendl H; Zipp F; Gold R; Tackenberg B; Weber F; Hemmer B; Strauch K; Heilmann-Heimbach S; Rawal R; Schminke U; Schmidt CO; Kacprowski T; Franke A; Laudes M; Dilthey AT; Celius EG; Sondergaard HB; Tegner J; Harbo HF; Oturai AB; Olafsson S; Eggertsson HP; Halldorsson BV; Hjaltason H; Olafsson E; Jonsdottir I; Stefansson K; Olsson T; Piehl F; Ekstroem TJ; Kockum I; Feinberg AP; Jagodic M
Article: NATURE IMMUNOLOGY. 2018;19(5):435-7
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling
Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: BMC BIOINFORMATICS. 2017;18(1):486
Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies
Needhamsen M; Ewing E; Lund H; Gomez-Cabrero D; Harris RA; Kular L; Jagodic M
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Letter: JOURNAL OF INTERNAL MEDICINE. 2021;290(2):473-476
Neurofilament light chain as a marker for cortical atrophy in multiple sclerosis without radiological signs of disease activity
Ineichen BV; Moridi T; Ewing E; Ouellette R; Manouchehrinia A; Stawiarz L; Ferreira D; Muehlboeck SJ; Kuhle J; Westman E; Leppert D; Hillert J; Olsson T; Kockum I; Piehl F; Granberg T
Thesis / dissertation: 2020
The role of epigenetics in multiple sclerosis development, progression and treatment
Ewing, Ewoud
Review: PHYSIOLOGICAL GENOMICS. 2017;49(9):447-461
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
Zheleznyakova GY; Piket E; Marabita F; Kakhki MP; Ewing E; Ruhrmann S; Needhamsen M; Jagodic M; Kular L

Anställningar

Anknuten till Forskning, Klinisk neurovetenskap, Karolinska Institutet, 2023-2025

Examina och utbildning

Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2022

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