Enrique Joffré

Enrique Joffré

E-postadress: enrique.joffre@ki.se
Besöksadress: Solnavägen 9, Biomedicum, 17165 Solna
Postadress: C1 Mikrobiologi, tumör- och cellbiologi, C1 CTMR Engstrand Juan Du, 171 77 Stockholm
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Om mig

  • Dissecting the transcriptional regulation of virulence and the spreading
    mechanisms of antibiotic resistance genes in pathogens with a One-health
    approach.
    I am a senior researcher at the Department of Microbiology, Tumor and Cell
    Biology (MTC), Karolinska Institutet, and a member of The Sjöling's group.
    https://www.jpiamr.eu/projects/parrtae/
    Jan 2011 — Oct 2015 Ph.D. in Microbiology. Dept. of Microbiology and
    Immunology. Inst. Biomedicine. University of Gothenburg
    Apr 2020 — Apr 2020 B.S. in Molecular Biology, Universidad Mayor de San
    Andr s. La Paz, Bolivia

Forskningsbeskrivning

  • My research is focused on dissecting the transcriptional regulation of
    virulence and the spreading mechanisms of plasmid-mediated resistance in
    pathogenic /E. coil /[urpopathogenic /E. coli/ (UPEC),
    enterotoxigenic /E. coli /(ETEC), enteroaggregative /E. coli/ (EAEC), and
    extraintestinal /E. coli/ (ExPEC)]. I use a multidisciplinary approach
    combining molecular epidemiology, basic microbiology, multi-omics (genomics,
    transcriptomics, metabolomics, and metagenomics), and mechanistic studies to
    better explain why specific clones of /E. coli/ or "superbugs" spread
    successfully into diverse microbial communities and cause infections in
    humans (e.g. urinary tract infection, diarrhea, and sepsis).
    I collaborate with different research groups within Sweden, Europe, and also
    LMICs such as Bolivia. #OneHealth.

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