Edvard Smith

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;44(5):116

Severe Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell Responses

Hedin W; Bergman P; Akhirunessa M; Soderholm S; Buggert M; Granberg T; Gredmark-Russ S; Smith CIE; Pettke A; Wahren Borgstrom E
Article: BLOOD ADVANCES. 2024;8(8):1981-1990

In BTK, phosphorylated Y223 in the SH3 domain mirrors catalytic activity, but does not in fl uence biological function

Estupinan HY; Bouderlique T; He C; Berglof A; Cappelleri A; Frengen N; Zain R; Karlsson MCI; Mansson R; Smith CIE
Article: CELL HOST & MICROBE. 2024;32(2):156-161.e3

Memory T cells effectively recognize the SARS-CoV-2 hypermutated BA.2.86 variant

Muller TR; Gao Y; Wu J; Ribeiro O; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Soderdahl G; Smith CIE; Lore K; Chen MS; Ljungman P; Ingelman-Sundberg HM; Ljunggren H-G; Osterborg A; Sette A; Grifoni A; Aleman S; Buggert M
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;44(2):50

Evaluation of Genetic or Cellular Impairments in Type I IFN Immunity in a Cohort of Young Adults with Critical COVID-19

Covill LE; Sendel A; Campbell TM; Piiroinen I; Enoksson SL; Borgstrom EW; Hansen S; Ma K; Marits P; Norlin AC; Smith CIE; Kahlin J; Eriksson LI; Bergman P; Bryceson YT
Article: NUCLEIC ACIDS RESEARCH. 2023;51(16):8532-8549

Large-scale expansions of Friedreich's ataxia GAA•TTC repeats in an experimental human system: role of DNA replication and prevention by LNA-DNA oligonucleotides and PNA oligomers

Rastokina A; Cebrian J; Mozafari N; Mandel NH; Smith CIE; Lopes M; Zain R; Mirkin SM
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(6):1075-1082

SARS-CoV-2 Antibodies in Commercial Immunoglobulin Products Show Markedly Reduced Cross-reactivities Against Omicron Variants

Lindahl H; Chen P; Aberg M; Ljunggren H-G; Buggert M; Aleman S; Smith CIE; Bergman P
Article: DIABETOLOGIA. 2023;66(8):1431-1441

Umbilical cord-derived mesenchymal stromal cells preserve endogenous insulin production in type 1 diabetes: a Phase I/II randomised double-blind placebo-controlled trial

Carlsson P-O; Espes D; Sisay S; Davies LC; Smith CIE; Svahn MG
Article: EBIOMEDICINE. 2023;94:104700

Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a one-year follow-up of the prospective clinical trial COVAXID

Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; oesterborg A; Smith CIE; Vesterbacka J; Wullimann D; Cuapio A; Akber M; Bogdanovic G; Muschiol S; aberg M; Lore K; Chen MS; Buggert M; Ljungman P; Aleman S; Ljunggren H-G
Article: HUMAN MUTATION. 2023;2023:1-12

BTKbase, Bruton Tyrosine Kinase Variant Database in X-Linked Agammaglobulinemia: Looking Back and Ahead

Schaafsma GCP; Vaeliaho J; Wang Q; Bergloef A; Zain R; Smith CIE; Vihinen M
Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452

Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states

Muller TRR; Sekine T; Trubach D; Niessl J; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Olofsson A; Hernandez SPA; Gao Y; Cai C; Soderdahl G; Smith CIE; Osterborg A; Lore K; Sallberg Chen M; Ljungman P; Ljunggren H-G; Karlsson ACC; Saini SK; Aleman S; Buggert M
Article: FRONTIERS IN BIOSCIENCE-LANDMARK. 2023;28(6):124

Original Exposure to Therapeutic BTK Inhibitors Induces Phenocopying of Btk29A Mutants in the Fruit Fly Drosophila melanogaster

Hamada-Kawaguchi N; Nore BF; Zain R; Engstroem Y; Smith CIE; Yamamoto D
Article: BLOOD ADVANCES. 2023;7(9):1929-1943

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

Naeem A; Utro F; Wang Q; Cha J; Vihinen M; Martindale S; Zhou Y; Ren Y; Tyekucheva S; Kim AS; Fernandes SM; Saksena G; Rhrissorrakrai K; Levovitz C; Danysh BP; Slowik K; Jacobs RA; Davids MS; Lederer JA; Zain R; Smith CIE; Leshchiner I; Parida L; Getz G; Brown JR
Article: NUCLEIC ACID THERAPEUTICS. 2023;33(2):117-131

Chemical Modifications and Design Influence the Potency of Huntingtin Antigene Oligonucleotides

Saher O; Zaghloul EMM; Umek T; Hagey DWW; Mozafari N; Danielsen MBB; Gouda ASS; Lundin KEE; Jorgensen PTT; Wengel J; Smith CIE; Zain R
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(1):136-150

Three Adult Cases of STAT1 Gain-of-Function with Chronic Mucocutaneous Candidiasis Treated with JAK Inhibitors

Borgstrom EW; Edvinsson M; Perez LP; Norlin AC; Enoksson SL; Hansen S; Fasth A; Friman V; Kampe O; Mansson R; Estupinan HY; Qing W; Tan Z; Lakshmikanth T; Smith CIE; Brodin P; Bergman P
Article: MOLECULAR BIOLOGY REPORTS. 2022;49(11):11187-11192

Specific properties of shRNA-mediated CCR5 downregulation that enhance the inhibition of HIV-1 infection in combination with shRNA targeting HIV-1 rev

Cardona ME; Hinkula J; Gustafsson K; Christensson B; Wahren B; Mohamed AJ; Smith CIE; Arteaga HJ
Article: IMMUNITY. 2022;55(9):1732-1746.e5

Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination

Gao Y; Cai C; Wullimann D; Niessl J; Rivera-Ballesteros O; Chen P; Lange J; Cuapio A; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Perez-Potti A; Sekine T; Muller TR; Boulouis C; Kammann T; Parrot T; Muvva JR; Sobkowiak M; Healy K; Bogdanovic G; Muschiol S; Soderdahl G; Osterborg A; Hellgren F; Grifoni A; Weiskopf D; Sette A; Lore K; Chen MS; Ljungman P; Sandberg JK; Smith CIE; Bergman P; Ljunggren H-G; Aleman S; Buggert M
Article: ISCIENCE. 2022;25(8):104698

Estimating the number of diseases - the concept of rare, ultra-rare, and hyper-rare

Smith CIE; Bergman P; Hagey DW
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(6):1130-1136

Neutralizing SARS-CoV-2 Antibodies in Commercial Immunoglobulin Products Give Patients with X-Linked Agammaglobulinemia Limited Passive Immunity to the Omicron Variant

Lindahl H; Klingstrom J; Da Silva Rodrigues R; Christ W; Chen P; Ljunggren H-G; Buggert M; Aleman S; Smith CIE; Bergman P
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(7):e20220202

Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

Campbell TM; Liu Z; Zhang Q; Moncada-Velez M; Covill LE; Zhang P; Darazam IA; Bastard P; Bizien L; Bucciol G; Enoksson SL; Jouanguy E; Karabela SN; Khan T; Kendir-Demirkol Y; Augusto Arias A; Mansouri D; Marits P; Marr N; Migeotte I; Moens L; Ozcelik T; Pellier I; Sendel A; Senoglu S; Shahrooei M; Smith CIE; Vandernoot I; Willekens K; Yasar KK; Bergman P; Abel L; Cobat A; Casanova J-L; Meyts I; Bryceson YT
Article: NUCLEIC ACID THERAPEUTICS. 2022;32(3):221-233

2′-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity

Honcharenko D; Rocha CSJ; Lundin KE; Maity J; Milton S; Tedebark U; Murtola M; Honcharenko M; Slaitas A; Smith CIE; Zain R; Stromberg R
Article: MOLECULAR MEDICINE. 2022;28(1):54

MAIT cell compartment characteristics are associated with the immune response magnitude to the BNT162b2 mRNA anti-SARS-CoV-2 vaccine

Boulouis C; Kammann T; Cuapio A; Parrot T; Gao Y; Mouchtaridi E; Wullimann D; Lange J; Chen P; Akber M; Ballesteros OR; Muvva JR; Smith CIE; Vesterbacka J; Kieri O; Nowak P; Bergman P; Buggert M; Ljunggren H-G; Aleman S; Sandberg JK
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(4):716-727

Elevated CD21^low B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with Common Variable Immunodeficiency

Bergman P; Wullimann D; Gao Y; Borgstrom EW; Norlin A-C; Enoksson SL; Aleman S; Ljunggren H-G; Buggert M; Smith CIE
Article: ADVANCED HEALTHCARE MATERIALS. 2022;11(5):e2101658

Growth Media Conditions Influence the Secretion Route and Release Levels of Engineered Extracellular Vesicles

Bost JP; Saher O; Hagey D; Mamand DR; Liang X; Zheng W; Corso G; Gustafsson O; Gorgens A; Smith CIE; Zain R; El Andaloussi S; Gupta D
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):185

Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides

Bost JP; Ojansivu M; Munson MJ; Wesen E; Gallud A; Gupta D; Gustafsson O; Saher O; Radler J; Higgins SG; Lehto T; Holme MN; Dahlen A; Engkvist O; Stromstedt P-E; Andersson S; Smith CIE; Stevens MM; Esbjorner EK; Collen A; El Andaloussi S
Article: ORPHANET JOURNAL OF RARE DISEASES. 2022;17(1):50

Clinical measurement of cellular DNA damage hypersensitivity in patients with DNA repair defects

Hammarsten O; Lyytikainen A; Thunstrom S; Ek T; Fasth A; Ekwall O; Cajander S; Borgstrom EW; Smith CIE; Johansson P
Article: MED. 2022;3(2):137-153.e3

Salivary IgG to SARS-CoV-2 indicates seroconversion and correlates to serum neutralization in mRNA-vaccinated immunocompromised individuals

Healy K; Pin E; Chen P; Soderdahl G; Nowak P; Mielke S; Hansson L; Bergman P; Smith CIE; Ljungman P; Valentini D; Blennow O; Osterborg A; Gabarrini G; Al-Manei K; Alkharaan H; Sobkowiak MJ; Yousef J; Mravinacova S; Cuapio A; Xu X; Akber M; Lore K; Hellstrom C; Muschiol S; Bogdanovic G; Buggert M; Ljunggren H-G; Hober S; Nilsson P; Aleman S; Chen MS
Article: MOLECULAR MEDICINE. 2022;28(1):20

NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals

Cuapio A; Boulouis C; Filipovic I; Wullimann D; Kammann T; Parrot T; Chen P; Akber M; Gao Y; Hammer Q; Strunz B; Potti AP; Ballesteros OR; Lange J; Muvva JR; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; Osterborg A; Smith CIE; Bogdanovic G; Muschiol S; Hellgren F; Lore K; Sobkowiak MJ; Gabarrini G; Healy K; Chen MS; Alici E; Bjorkstrom NK; Buggert M; Ljungman P; Sandberg JK; Aleman S; Ljunggren H-G
Article: LEUKEMIA. 2022;36(2):476-481

Covid-19 in patients with chronic lymphocytic leukemia: clinical outcome and B- and T-cell immunity during 13 months in consecutive patients

Blixt L; Bogdanovic G; Buggert M; Gao Y; Hober S; Healy K; Johansson H; Kjellander C; Mravinacova S; Muschiol S; Nilsson P; Palma M; Pin E; Smith CIE; Stromberg O; Chen MS; Zain R; Hansson L; Osterborg A
Journal article: CLINICAL IMMUNOLOGY COMMUNICATIONS. 2021;1:20-24

COVID-19 in a patient with Good's syndrome and in 13 patients with common variable immunodeficiency.

Lindahl H; Smith CIE; Bergman P
Article: EBIOMEDICINE. 2021;74:103705

Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial

Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Chen P; Soderdahl G; Osterborg A; Smith CIE; Wullimann D; Vesterbacka J; Lindgren G; Blixt L; Friman G; Wahren-Borgstrom E; Nordlander A; Gomez AC; Akber M; Valentini D; Norlin A-C; Thalme A; Bogdanovic G; Muschiol S; Nilsson P; Hober S; Lore K; Chen MS; Buggert M; Ljunggren H-G; Ljungman P; Aleman S
Article: NUCLEIC ACID THERAPEUTICS. 2021;31(6):443-456

Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System

Umek T; Olsson T; Gissberg O; Saher O; Zaghloul EM; Lundin KE; Wengel J; Hanse E; Zetterberg H; Vizlin-Hodzic D; Smith CIE; Zain R
Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098

Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles

Gupta D; Wiklander OPB; Goergens A; Conceicao M; Corso G; Liang X; Seow Y; Balusu S; Feldin U; Bostancioglu B; Jawad R; Mamand DR; Lee YXF; Hean J; Mager I; Roberts TC; Gustafsson M; Mohammad DK; Sork H; Backlund A; Lundin P; de Fougerolles A; Smith CIE; Wood MJA; Vandenbroucke RE; Nordin JZ; El-Andaloussi S
Article: BIOMEDICINES. 2021;9(8):1046

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo

Bazaz S; Lehto T; Tops R; Gissberg O; Gupta D; Bestas B; Bost J; Wiklander OPB; Sork H; Zaghloul EM; Mamand DR; Hallbrink M; Sillard R; Saher O; Ezzat K; Smith CIE; El Andaloussi S; Lehto T
Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4348

X-linked recessive TLR7 deficiency in ∼1% of men under 60 years old with life-threatening COVID-19

Asano T; Boisson B; Onodi F; Matuozzo D; Moncada-Velez M; Renkilaraj MRLM; Zhang P; Meertens L; Bolze A; Materna M; Korniotis S; Gervais A; Talouarn E; Bigio B; Seeleuthner Y; Bilguvar K; Zhang Y; Neehus A-L; Ogishi M; Pelham SJ; Le Voyer T; Rosain J; Philippot Q; Soler-Palacin P; Colobran R; Martin-Nalda A; Riviere JG; Tandjaoui-Lambiotte Y; Chaibi K; Shahrooei M; Darazam IA; Olyaei NA; Mansouri D; Palabiyik F; Ozcelik T; Novelli G; Novelli A; Casari G; Aiuti A; Carrera P; Bondesan S; Barzaghi F; Rovere-Querini P; Tresoldi C; Franco JL; Rojas J; Reyes LF; Bustos IG; Arias AA; Morelle G; Kyheng C; Troya J; Planas-Serra L; Schluter A; Gut M; Pujol A; Allende LM; Rodriguez-Gallego C; Flores C; Cabrera-Marante O; Pleguezuelo DE; de Diego RP; Keles S; Aytekin G; Akcan OM; Bryceson YT; Bergman P; Brodin P; Smole D; Smith CIE; Norlin A-C; Campbell TM; Covill LE; Hammarstrom L; Pan-Hammarstrom Q; Abolhassani H; Mane S; Marr N; Ata M; Al Ali F; Khan T; Spaan AN; Dalgard CL; Bonfanti P; Biondi A; Tubiana S; Burdet C; Nussbaum R; Kahn-Kirby A; Snow AL; Bustamante J; Puel A; Boisson-Dupuis S; Zhang S-Y; Beziat V; Lifton RP; Bastard P; Notarangelo LD; Abel L; Su HC; Jouanguy E; Amara A; Soumelis V; Cobat A; Zhang Q; Casanova J-L
Article: LEUKEMIA. 2021;35(5):1317-1329

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

Estupinan HY; Wang Q; Berglof A; Schaafsma GCP; Shi Y; Zhou L; Mohammad DK; Yu L; Vihinen M; Zain R; Smith CIE
Article: HEMASPHERE. 2021;5(5):e564

Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia

Mulder TA; Pena-Perez L; Berglof A; Meinke S; Estupinan HY; Heimersson K; Zain R; Mansson R; Smith CIE; Palma M
Article: PHARMACEUTICS. 2021;13(1):116

Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides

Daralnakhla H; Saher O; Zamolo S; Bazaz S; P. Bost J; Heitz M; Lundin KE; El Andaloussi S; Darbre T; Reymond J-L; Zain R; Smith CIE
Article: BLOOD ADVANCES. 2020;4(11):2439-2450

Novel mouse model resistant to irreversible BTK inhibitors: a tool identifying new therapeutic targets and side effects

Estupinan HY; Bouderlique T; He C; Berglof A; Gupta D; Saher O; Daza Cruz MA; Pena-Perez L; Yu L; Zain R; Karlsson MCI; Mansson R; Smith CIE
Article: CANCERS. 2020;12(5):E1143-1143

Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells

Sadeghi L; Arvidsson G; Merrien M; Wasik AM; Gorgens A; Smith CIE; Sander B; Wright AP
Article: PHARMACEUTICS. 2019;11(12):E666-666

Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations

Saher O; Lehto T; Gissberg O; Gupta D; Gustafsson O; EL Andaloussi S; Darbre T; Lundin KE; Smith CIE; Zain R
Article: BLOOD ADVANCES. 2019;3(18):2722-2731

Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6

Jarviaho T; Bang B; Zachariadis V; Taylan F; Moilanen J; Mottonen M; Smith CIE; Harila-Saari A; Niinimaki R; Nordgren A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2019;7(5):1568-1577

Long-Term Outcome of WHIM Syndrome in 18 Patients: High Risk of Lung Disease and HPV-Related Malignancies

Dotta L; Notarangelo LD; Moratto D; Kumar R; Porta F; Soresina A; Lougaris V; Plebani A; Smith CIE; Norlin A-C; Gomez Raccio AC; Bubanska E; Bertolini P; Amendola G; Visentini M; Fiorilli M; Venuti A; Badolato R
Article: MOLECULES. 2019;24(6):E1180-1180

Oligonucleotide-Palladacycle Conjugates as Splice-Correcting Agents

Hande M; Saher O; Lundin KE; Smith CIE; Zain R; Lonnberg T
Article: MOLECULES. 2019;24(5):E1000-1000

Oligonucleotide Binding to Non-B-DNA in MYC

Umek T; Sollander K; Bergquist H; Wengel J; Lundin KE; Smith CIE; Zain R
Article: CLINICAL IMMUNOLOGY. 2019;200:39-42

Precursor B-cell development in bone marrow of Good syndrome patients.

Del Pino Molina L; Wentink M; van Deuren M; van Hagen PM; Smith CIE; van der Burg M
Article: METHODS IN MOLECULAR BIOLOGY. 2019;2036:3-16

Chemical Development of Therapeutic Oligonucleotides.

Lundin KE; Gissberg O; Smith CIE; Zain R
Article: PLOS ONE. 2019;14(2):e0211651

The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study

Xu Y; Gissberg O; Pabon-Martinez YV; Wengel J; Lundin KE; Smith CIE; Zain R; Nilsson L; Villa A
Article: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2018;132:29-40

Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity

Saher O; Rocha CSJ; Zaghioul EM; Wiklander OPB; Zamolo S; Heitz M; Ezzat K; Gupta D; Reymond J-L; Zain R; Hollfelder F; Darbre T; Lundin KE; El Andaloussi S; Smith CIE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;504(4):749-752

Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression

Fathi NN; Mohammad DK; Gorgens A; El Andaloussi S; Zain R; Nore BF; Smith CIE
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(2):212-224

Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes

Palma M; Krstic A; Perez LP; Bergloef A; Meinke S; Wang Q; Blomberg KEM; Kamali-Moghaddam M; Shen Q; Jaremko G; Lundin J; De Paepe A; Hoeglund P; Kimby E; OEsterborg A; Mansson R; Smith CIE
Article: BMC PEDIATRICS. 2018;18(1):285

Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report

Lundin KE; Wang Q; Hamasy A; Marits P; Uzunel M; Wirta V; Wikstrom A-C; Fasth A; Ekwall O; Smith CIE
Article: LAKARTIDNINGEN. 2017;114:EWYL

[Gene therapy – from idea to reality].

Smith E; Blomberg P
Article: SCIENTIFIC REPORTS. 2017;7(1):11043

LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures

Pabon-Martinez YV; Xu Y; Villa A; Lundin KE; Geny S; Nguyen C-H; Pedersen EB; Jorgensen PT; Wengel J; Nilsson L; Smith CIE; Zain R
Article: CHEMICAL COMMUNICATIONS. 2017;53(49):6653-6656

Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor

Garcia YR; Pabon-Martinez YV; Smith CIE; Madder A
Article: ACS OMEGA. 2017;2(5):2165-2177

Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies

Hartono YD; Pabon-Martinez YV; Uyar A; Wengel J; Lundin KE; Zain R; Smith CIE; Nilsson L; Villa A
Article: NUCLEIC ACIDS RESEARCH. 2017;45(9):5153-5169

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression

Zaghloul EM; Gissberg O; Moreno PMD; Siggens L; Hallbrink M; Jorgensen AS; Ekwall K; Zain R; Wengel J; Lundin KE; Smith CIE
Article: LEUKEMIA. 2017;31(1):177-185

Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant

Hamasy A; Wang Q; Blomberg KEM; Mohammad DK; Yu L; Vihinen M; Berglof A; Smith CIE
Article: PLOS ONE. 2017;12(4):e0174909

ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library

Gustafsson MO; Mohammad' DK; Ylosmaki E; Choi H; Shrestha S; Wang Q; Nore BF; Saksela K; Smith CIE
Article: NUCLEIC ACID THERAPEUTICS. 2016;26(6):381-391

Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity

Rocha CSJ; Lundin KE; Behlke MA; Zain R; EL Andaloussi S; Smith CIE
Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 2016;78:63-74

Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin

Mohammad DK; Nore BF; Gustafsson MO; Mohamed AJ; Smith CIE
Article: NUCLEIC ACID THERAPEUTICS. 2016;26(3):183-189

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs

Gissberg O; Zaghloul EM; Lundin KE; Chi-Hung N; Landras-Guetta C; Wengel J; Zain R; Smith CIE
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2016;14(14):3584-3590

Fast and efficient synthesis of Zorro-LNA type 3′-5′-5′-3′ oligonucleotide conjugates via parallel in situ stepwise conjugation

Gissberg OI; Jezowska M; Zaghloul EM; Bungsu NI; Stromberg R; Smith CIE; Lundin KE; Honcharenko M
Article: STEM CELL REPORTS. 2016;6(4):607-617

Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells

Mansson-Broberg A; Rodin S; Bulatovic I; Ibarra C; Lofling M; Genead R; Wardell E; Felldin U; Granath C; Alici E; Le Blanc K; Smith CIE; Salasova A; Westgren M; Sundstrom E; Uhlen P; Arenas E; Sylven C; Tryggvason K; Corbascio M; Simonson OE; Osterholm C; Grinnemo K-H
Article: NUCLEIC ACIDS RESEARCH. 2016;44(5):2007-2019

Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

Geny S; Moreno PMD; Krzywkowski T; Gissberg O; Andersen NK; Isse AJ; El-Madani AM; Lou C; Pabon YV; Anderson BA; Zaghloul EM; Zain R; Hrdlicka PJ; Jorgensen PT; Nilsson M; Lundin KE; Pedersen EB; Wengel J; Smith CIE
Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2016;5(3):e290

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency

Sork H; Nordin JZ; Turunen JJ; Wiklander OPB; Bestas B; Zaghloul EM; Margus H; Padari K; Duru AD; Corso G; Bost J; Vader P; Pooga M; Smith CIE; Wood MJA; Schiffelers RM; Hallbrink M; Andaloussi SEL
Article: SCIENTIFIC REPORTS. 2016;6:22519

Cells release subpopulations of exosomes with distinct molecular and biological properties

Willms E; Johansson HJ; Mager I; Lee Y; Blomberg KEM; Sadik M; Alaarg A; Smith CIE; Lehtio J; Andaloussi SEL; Wood MJA; Vader P
Article: GENOMICS DATA. 2016;7:88-89

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration.

Roberts TC; Blomberg KEM; Smith CIE; El Andaloussi S; Wood MJA
Article: LEUKEMIA & LYMPHOMA. 2016;57(1):183-192

A murine model of acute myeloid leukemia with Evi1 overexpression and autocrine stimulation by an intracellular form of GM-CSF in DA-3 cells

Cardona ME; Simonson OE; Oprea II; Moreno PMD; Silva-Lara MF; Mohamed AJ; Christensson B; Gahrton G; Dilber MS; Smith CIE; Arteaga HJ
Article: PLOS ONE. 2016;11(8):e0160255

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

Mohammad DK; Ali RH; Turunen JJ; Nore BF; Smith CIE
Article: PLOS ONE. 2016;11(11):e0165788

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)_n Repeats by PNA or LNA Targeting

Bergquist H; Rocha CSJ; Alvarez-Asencio R; Chi-Hung N; Rutland MW; Smith CIE; Good L; Nielsen PE; Zain R
Article: RSC ADVANCES. 2016;6(56):51367-51373

Synthetic m₃G-CAP attachment necessitates a minimum trinucleotide constituent to be recognised as a nuclear import signal

Honcharenko M; Bestas B; Jezowska M; Wojtczak BA; Moreno PMD; Romanowska J; Bachle SM; Darzynkiewicz E; Jemielity J; Smith CIE; Stromberg R
Article: RSC ADVANCES. 2016;6(10):8326-8337

Clickable trimethylguanosine cap analogs modified within the triphosphate bridge: synthesis, conjugation to RNA and susceptibility to degradation

Wojtczak BA; Warminski M; Kowalska J; Lukaszewicz M; Honcharenko M; Smith CIE; Stromberg R; Darzynkiewicz E; Jemielity J
Article: CHEMICAL COMMUNICATIONS. 2015;51(99):17552-17555

Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates

Garcia YR; Iyer A; Van Lysebetten D; Pabon YV; Louage B; Honcharenko M; De Geest BG; Smith CIE; Stromberg R; Madder A
Article: CLINICAL IMMUNOLOGY. 2015;161(2):366-372

Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene

Lundin KE; Hamasy A; Backe PH; Moens LN; Falk-Sorqvist E; Elgstoen KB; Morkrid L; Bjoras M; Granert C; Norlin A-C; Nilsson M; Christensson B; Stenmark S; Smith CIE
Article: HUMAN MOLECULAR GENETICS. 2015;24(23):6756-6768

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration

Roberts TC; Johansson HJ; McClorey G; Godfrey C; Blomberg KEM; Coursindel T; Gait MJ; Smith CIE; Lehtio J; El Andaloussi S; Wood MJA
Article: HUMAN MUTATION. 2015;36(6):638-647

Characterization of All Possible Single-Nucleotide Change Caused Amino Acid Substitutions in the Kinase Domain of Bruton Tyrosine Kinase

Valiaho J; Faisal I; Ortutay C; Smith CIE; Vihinen M
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2015;13(18):5273-5278

Cyclodextrin-peptide conjugates for sequence specific DNA binding

Garcia YR; Zelenka J; Pabon YV; Iyer A; Budesinsky M; Kraus T; Smith CIE; Madder A
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2015;82:186-193

RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form

Rocha CSJ; Wiklander OPB; Larsson L; Moreno PMD; Parini P; Lundin KE; Smith CIE
Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2015;11(4):879-883

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

Nordin JZ; Lee Y; Vader P; Maeger I; Johansson HJ; Heusermann W; Wiklander OPB; Hallbrink M; Seow Y; Bultema JJ; Gilthorpe J; Davies T; Fairchild PJ; Gabrielsson S; Meisner-Kober NC; Lehtio J; Smith CIE; Wood MJA; Andaloussi SEL
Article: NUCLEIC ACID THERAPEUTICS. 2015;25(2):65-77

Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides

Jarver P; Zaghloul EM; Arzumanov AA; Saleh AF; McClorey G; Hammond SM; Hallbrink M; Langel U; Smith CIE; Wood MJA; Gait MJ; EL Andaloussi S
Article: CHEMICAL COMMUNICATIONS. 2015;51(19):4044-4047

Nuclease resistant oligonucleotides with cell penetrating properties

Milton S; Honcharenko D; Rocha CSJ; Moreno PMD; Smith CIE; Stromberg R
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26316

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.

Wiklander OPB; Nordin JZ; O'Loughlin A; Gustafsson Y; Corso G; Mäger I; Vader P; Lee Y; Sork H; Seow Y; Heldring N; Alvarez-Erviti L; Smith CIE; Le Blanc K; Macchiarini P; Jungebluth P; Wood MJA; Andaloussi SE
Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2014;3(11):e212

Correlating In Vitro Splice Switching Activity With Systemic In Vivo Delivery Using Novel ZEN-modified Oligonucleotides

Hammond SM; McClorey G; Nordin JZ; Godfrey C; Stenler S; Lennox KA; Smith CIE; Jacobi AM; Varela MA; Lee Y; Behlke MA; Wood MJA; Andaloussi SEL
Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(9):4067-4081

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

Bestas B; Moreno PMD; Blomberg KEM; Mohammad DK; Saleh AF; Sutlu T; Nordin JZ; Guterstam P; Gustafsson MO; Kharazi S; Piatosa B; Roberts TC; Behlke MA; Wood MJA; Gait MJ; Lundin KE; El Andaloussi S; Mansson R; Berglof A; Wengel J; Smith CIE
Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2014;3(7):e172

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression

Oprea II; Viola JR; Moreno PMD; Simonson OE; Rodin S; Teller N; Tryggvason K; Lundin KE; Girnita L; Smith CIE
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;133(5):1410-1419.13

Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels

Sassi A; Lazaroski S; Wu G; Haslam SM; Fliegauf M; Mellouli F; Patiroglu T; Unal E; Ozdemir MA; Jouhadi Z; Khadir K; Ben-Khemis L; Ben-Ali M; Ben-Mustapha I; Borchani LH; Pfeifer D; Jakob T; Khemiri M; Asplund AC; Gustafsson MO; Lundin KE; Falk-Soerqvist E; Moens LN; Gungor HE; Engelhardt KR; Dziadzio M; Stauss H; Fleckenstein B; Meier R; Prayitno K; Maul-Pavicic A; Schaffer S; Rakhmanov M; Henneke P; Kraus H; Eibel H; Koelsch U; Nadifi S; Nilsson M; Bejaoui M; Schaeffer AA; Smith CIE; Dell A; Barbouche M-R; Grimbacher B
Article: NUCLEIC ACID THERAPEUTICS. 2014;24(1):13-24

Design and Application of Bispecific Splice-Switching Oligonucleotides

Bestas B; McClorey G; Tedebark U; Moreno PMD; Roberts TC; Hammond SM; Smith CIE; Wood MJA; Andaloussi SEL
Article: SCIENCE. 2014;343(6168):294-297

Btk29A Promotes Wnt4 Signaling in the Niche to Terminate Germ Cell Proliferation in Drosophila

Hamada-Kawaguchi N; Nore BF; Kuwada Y; Smith CIE; Yamamoto D
Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2014;3(1):e140

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

Stenler S; Wiklander OPB; Badal-Tejedor M; Turunen J; Nordin JZ; Hallengard D; Wahren B; Andaloussi SEL; Rutland MW; Smith CIE; Lundin KE; Blomberg P
Article: PLOS ONE. 2014;9(12):e114901

Diagnostics of Primary Immunodeficiency Diseases: A Sequencing Capture Approach

Moens LN; Falk-Sorqvist E; Asplund AC; Bernatowska E; Smith CIE; Nilsson M
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(24):7921-7928

Synthesis and evaluation of stability of m₃G-CAP analogues in serum-supplemented medium and cytosolic extract

Honcharenko M; Zytek M; Bestas B; Moreno P; Jemielity J; Darzynkiewicz E; Smith CIE; Stromberg R
Article: MOLECULAR AND CELLULAR BIOLOGY. 2013;33(16):3214-3226

Dual Phosphorylation of Btk by Akt/Protein Kinase B Provides Docking for 14-3-3ζ, Regulates Shuttling, and Attenuates both Tonic and Induced Signaling in B Cells

Mohammad DK; Nore BF; Hussain A; Gustafsson MO; Mohamed AJ; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(10):7338-7350

Signaling of the ITK (Interleukin 2-inducible T Cell Kinase)-SYK (Spleen Tyrosine Kinase) Fusion Kinase Is Dependent on Adapter SLP-76 and on the Adapter Function of the Kinases SYK and ZAP70

Hussain A; Mohammad DK; Gustafsson MO; Uslu M; Hamasy A; Nore BF; Mohamed AJ; Smith CIE
Article: NUCLEIC ACIDS RESEARCH. 2013;41(5):3257-3273

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

Moreno PMD; Geny S; Pabon YV; Bergquist H; Zaghloul EM; Rocha CSJ; Oprea II; Bestas B; El Andaloussi S; Jorgensen PT; Pedersen EB; Lundin KE; Zain R; Wengel J; Smith CIE
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2012;22(17):5635-5638

Diaminopropionic acid lipopeptides: Characterization studies of polyplexes aimed at pDNA delivery

Viola JR; Stromberg R; Simonson OE; El Andaloussi S; Smith CIE; Murtola M
Article: JOURNAL OF CONTROLLED RELEASE. 2012;162(1):1-8

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions

Ezzat K; Zaghloul EM; Andaloussi SEL; Lehto T; El-Sayed R; Magdy T; Smith CIE; Langel U
Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2012;1(8):e39

Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy

Roberts TC; Blomberg KEM; McClorey G; Andaloussi SEL; Godfrey C; Betts C; Coursindel T; Gait MJ; Smith CIE; Wood MJA
Article: BLOOD. 2012;120(4):768-777

Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques

Skold AE; Hasan M; Vargas L; Saidi H; Bosquet N; Le Grand R; Smith CIE; Spetz A-L
Article: MOLECULAR AND CELLULAR BIOLOGY. 2012;32(13):2440-2453

Regulation of Nucleocytoplasmic Shuttling of Bruton's Tyrosine Kinase (Btk) through a Novel SH3-Dependent Interaction with Ankyrin Repeat Domain 54 (ANKRD54)

Gustafsson MO; Hussain A; Mohammad DK; Mohamed AJ; Vivian N; Metalnikov P; Colwill K; Pawson T; Smith CIE; Nore BF
Article: PLOS ONE. 2012;7(5):e36804

Ischemia-Reperfusion Injury and Pregnancy Initiate Time-Dependent and Robust Signs of Up-Regulation of Cardiac Progenitor Cells

Genead R; Fischer H; Hussain A; Jaksch M; Andersson AB; Ljung K; Bulatovic I; Franco-Cereceda A; Elsheikh E; Corbascio M; Smith CIE; Sylven C; Grinnemo K-H
Article: PLOS ONE. 2012;7(5):e35640

Differential Evolutionary Wiring of the Tyrosine Kinase Btk

Nawaz HM; Kylsten P; Hamada N; Yamamoto D; Smith CIE; Lindvall JM
Article: RSC ADVANCES. 2012;2(33):12949-12962

Capping of oligonucleotides with "clickable'' m₃G-CAPs

Honcharenko M; Romanowska J; Alvira M; Jezowska M; Kjellgren M; Smith CIE; Stromberg R
Article: NUCLEIC ACIDS RESEARCH. 2011;39(16):7077-7091

Compensatory signals associated with the activation of human GC 5' splice sites

Kralovicova J; Hwang G; Asplund AC; Churbanov A; Smith CIE; Vorechovsky I
Article: MOLECULAR THERAPY. 2011;19(8):1457-1467

A Peptide-based Vector for Efficient Gene Transfer In Vitro and In Vivo

Lehto T; Simonson OE; Mager I; Ezzat K; Sork H; Copolovici D-M; Viola JR; Zaghloul EM; Lundin P; Moreno PMD; Mae M; Oskolkov N; Suhorutsenko J; Smith CIE; Andaloussi SEL
Article: NUCLEIC ACIDS RESEARCH. 2011;39(12):5284-5298

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

Ezzat K; EL Andaloussi S; Zaghloul EM; Lehto T; Lindberg S; Moreno PMD; Viola JR; Magdy T; Abdo R; Guterstam P; Sillard R; Hammond SM; Wood MJA; Arzumanov AA; Gait MJ; Smith CIE; Hallbrink M; Langel U
Article: NUCLEIC ACIDS RESEARCH. 2011;39(9):3972-3987

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

Andaloussi SEL; Lehto T; Maeger I; Rosenthal-Aizman K; Oprea II; Simonson OE; Sork H; Ezzat K; Copolovici DM; Kurrikoff K; Viola JR; Zaghloul EM; Sillard R; Johansson HJ; Hassane FS; Guterstam P; Suhorutsenko J; Moreno PMD; Oskolkov N; Haelldin J; Tedebark U; Metspalu A; Lebleu B; Lehtioe J; Smith CIE; Langel U
Article: NUCLEIC ACIDS RESEARCH. 2011;39(3):1142-1154

Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA

Zaghloul EM; Madsen AS; Moreno PMD; Oprea II; El-Andaloussi S; Bestas B; Gupta P; Pedersen EB; Lundin KE; Wengel J; Smith CIE
Article: EXPERT OPINION ON THERAPEUTIC PATENTS. 2011;21(1):115-119

Circular RNA interference effector molecules (WO10084371)

Lundin P; Moreno PMD; Smith CIE; Andaloussi SEL
Article: MOLECULAR PHARMACEUTICS. 2010;7(3):652-663

Formulation and Delivery of Splice-Correction Antisense Oligonucleotides by Amino Acid Modified Polyethylenimine

Zaghloul EM; Viola JR; Zuber G; Smith CIE; Lundin KE
Article: MOLECULAR BIOTECHNOLOGY. 2010;45(2):171-179

Temperature-Assisted Cyclic Hybridization (TACH): An Improved Method for Supercoiled DNA Hybridization

Oprea II; Simonson OE; Moreno PMD; Viola JR; Lundin KE; Smith CIE
Article: JOURNAL OF CONTROLLED RELEASE. 2010;141(1):42-51

Delivery of nucleic acids with a stearylated (RxR)₄ peptide using a non-covalent co-incubation strategy

Lehto T; Abes R; Oskolkov N; Suhorutsenko J; Copolovici D-M; Mager I; Viola JR; Simonson OE; Ezzat K; Guterstam P; Eriste E; Smith CIE; Lebleu B; El Andaloussi S; Langel U
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;390(3):892-896

Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein

Hussain A; Faryal R; Nore BF; Mohamed AJ; Smith CIE
Article: GENE THERAPY. 2009;16(12):1429-1440

Fatty acid-spermine conjugates as DNA carriers for nonviral in vivo gene delivery

Viola JR; Leijonmarck H; Simonson OE; Oprea II; Frithiof R; Purhonen P; Moreno PMD; Lundin KE; Stromberg R; Smith CIE
Article: FEBS JOURNAL. 2009;276(22):6714-6724

NF-κB regulates the transcription of protein tyrosine kinase Tec

Yu L; Simonson OE; Mohamed AJ; Smith CIE
Article: GENETICA. 2009;137(1):47-56

Nanotechnology approaches for gene transfer

Lundin KE; Simonson OE; Moreno PMD; Zaghloul EM; Oprea II; Svahn MG; Smith CIE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;385(1):100-105

Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets

Yu L; Mohanram V; Simonson OE; Smith CIE; Spetz A-L; Mohamed AJ
Article: MOLECULAR IMMUNOLOGY. 2009;46(10):2140-2146

Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: A cohort study

Toth B; Volokha A; Mihas A; Pac M; Bernatowska E; Kondratenko I; Polyakov A; Erdoes M; Pasic S; Bataneant M; Szaflarska A; Mironska K; Richter D; Stavrik K; Avcin T; Marton G; Nagy K; Derfalvi B; Szolnoky M; Kalmar A; Belevtsev M; Guseva M; Rugina A; Krivan G; Timar L; Nyul Z; Mosdosi B; Kareva L; Peova S; Chernyshova L; Gherghina I; Serban M; Conley ME; Notarangelo LD; Smith CIE; van Dongen J; van der Burg M; Marodi L
Article: BMC GENOMICS. 2009;10:233

Transcriptional signatures of Itk-deficient CD3⁺, CD4⁺ and CD8⁺ T-cells

Blomberg KEM; Boucheron N; Lindvall JM; Yu L; Raberger J; Berglof A; Ellmeier W; Smith CIE
Article: NUCLEIC ACIDS RESEARCH. 2009;37(6):1925-1935

A synthetic snRNA m₃G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids

Moreno PMD; Wenska M; Lundin KE; Wrange O; Stromberg R; Smith CIE
Article: IMMUNOLOGICAL REVIEWS. 2009;228(1):58-73

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

Mohamed AJ; Yu L; Backesjo C-M; Vargas L; Faryal R; Aints A; Christensson B; Berglof A; Vihinen M; Nore BF; Smith CIE
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2009;53(1):18-23

Gene Transfer to Mouse Heart and Skeletal Muscles Using a Minicircle Expressing Human Vascular Endothelial Growth Factor

Stenler S; Andersson A; Simonson OE; Lundin KE; Chen Z-Y; Kay MA; Smith CIE; Sylven C; Blomberg P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2008;377(2):584-588

Expression profiling of chicken DT40 lymphoma cells indicates clonal selection of knockout and gene reconstituted cells

Nawaz HM; Blomberg KEM; Lindvall JM; Kurosaki T; Smith CIE
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(46):17919-17924

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells

Raberger J; Schebesta A; Sakaguchi S; Boucheron N; Blomberg KEM; Berglof A; Kolbe T; Smith CIE; Ruelicke T; Ellmeier W
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;143(2):248-252

The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival

Wang X; Asplund AC; Porwit A; Flygare J; Smith CIE; Christensson B; Sander B
Article: NUCLEIC ACIDS SYMPOSIUM SERIES (2004). 2008;(52):27-28

Building biologically active nucleic acid nanocomplexes.

Smith CIE; Lundin KE; Simonson OE; Moreno PMD; Svahn MG; Wenska M; Strömberg R
Article: JOURNAL OF IMMUNOLOGY. 2008;181(1):288-298

Dual functions of Bruton's tyrosine kinase and tec kinase during Fcγ receptor-induced signaling and phagocytosis

Jongstra-Bilen J; Cano AP; Hasija M; Xiao H; Smith CIE; Cybulsky MI
Article: BLOOD. 2008;111(9):4617-4626

Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-κB

Yu L; Mohamed AJ; Simonson OE; Vargas L; Blomberg KEM; Bjorkstrand B; Arteaga HJ; Notre BF; Smith CIE
Article: IMMUNOLOGY. 2008;123(2):239-249

Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice

Hasan M; Lopez-Herrera G; Blomberg KEM; Lindvall JM; Berglof A; Smith CIE; Vargas L
Article: JOURNAL OF GENE MEDICINE. 2008;10(1):101-109

Sequence-specific inhibition of RNA polymerase III-dependent transcription using Zorro locked nucleic acid (LNA)

Ge R; Svahn MG; Simonson OE; Mohamed AJ; Lundin KE; Smith CIE
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2007;27(6):640-646

Contiguous x-chromosome deletion syndrome encompassing the BTK, TIMM8A, TAF7L, and DRP2 genes

Sediva A; Smith CIE; Asplund AC; Hadac J; Janda A; Zeman J; Hansikova H; Dvorakova L; Mrazova L; Velbri S; Koehler C; Roesch K; Sullivan KE; Futatani T; Ochs HD
Article: FASEB JOURNAL. 2007;21(8):1902-1914

Zorro locked nucleic acid induces sequence-specific gene silencing

Ge R; Heinonen JE; Svahn MG; Mohamed AJ; Lundin KE; Smith CIE
Article: CANCER GENE THERAPY. 2007;14(3):227-232

Long-term follow-up of gene-marked CD34⁺ cells after autologous stem cell transplantation for multiple myeloma

Alici E; Bjorkstrand B; Treschow A; Aints A; Smith CIE; Gahrton G; Dilber MS
Article: ANTISENSE AND NUCLEIC ACID DRUG DEVELOPMENT. 2007;17(1):80-94

Self-assembling supramolecular complexes by single-stranded extension from plasmid DNA

Svahn MG; Hasan M; Sigot V; Valle-Delgado JJ; Rutland MW; Lundin KE; Smith CIE
Article: HUMAN MUTATION. 2006;27(12):1209-1217

BDTKbase:: The mutation database for X-linked agammaglobullinemia

Valiaho J; Smith CIE; Vihinen M
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2006;134(6):640-644

Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation

Sanmun D; Garwicz D; Smith CIE; Palmblad J; Fadeel B
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;346(2):461-469

Distinct gene expression signature in Btk-defective T1 B-cells

Lindvall JM; Blomberg KEM; Berglof A; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(26):18201-18207

Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1

Yu L; Mohamed AJ; Vargas L; Berglof A; Finn G; Lu KP; Smith CIE
Article: NEW BIOTECHNOLOGY. 2005;22(5-6):185-192

Increased stability and specificity through combined hybridization of peptide nucleic acid (PNA) and locked nucleic acid (LNA) to supercoiled plasmids for PNA-anchored "Bioplex" formation

Lundin KE; Hasan M; Moreno PM; Törnquist E; Oprea IL; Svahn MG; Simonson EO; Smith CIE
Article: INTERNATIONAL JOURNAL OF CANCER. 2005;117(3):418-430

Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1

Sander B; Flygare J; Porwit-MacDonald A; Smith CIE; Emanuelsson E; Kimby E; Liden J; Christensson B
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2005;62(5):429-436

Genetically modified autoactivated cells expressing intracellular forms of GM-CSF as a model for regulated administration of cytokines

Arteaga HJ; Mohamed AJ; Christensson B; Mahdy E; Gahrton G; Smith CIE; Dilber MS
Article: FEBS LETTERS. 2005;579(19):4131-4137

Functional replacement of Drosophila Btk29A with human Btk in male genital development and survival

Hamada N; Bäckesjö CM; Smith CIE; Yamamoto D
Article: CELLULAR IMMUNOLOGY. 2005;235(1):46-55

Differential expression and molecular characterisation of Lmo7, Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells

Lindvall JM; Blomberg KEM; Wennborg A; Smith CIE
Article: ANTISENSE AND NUCLEIC ACID DRUG DEVELOPMENT. 2005;15(2):139-144

Inducible H1 promoter-driven lentiviral siRNA expression by stuffer reporter deletion

Heinonen JE; Mohamed AJ; Nore BF; Smith CIE
Article: JOURNAL OF CONTROLLED RELEASE. 2004;98(1):169-177

Protease-induced release of functional peptides from bioplexes

Svahn MG; Salih G; Simonson EO; Smith CIE; Brandén LJ
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(7):1981-1991

Gene expression profile of B cells from Xid mice and Btk knockout mice

Lindvall JM; Blomberg KEM; Berglöf A; Yang O; Smith CIE; Islam TC
Article: NEW BIOTECHNOLOGY. 2004;21(2):51-59

Cooperative strand invasion of supercoiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras

Lundin KE; Ge RB; Svahn MG; Törnquist E; Leijon M; Brandén LJ; Smith CIE
Article: GLYCOCONJUGATE JOURNAL. 2004;21(5):227-241

Ligands of the asialoglycoprotein receptor for targeted gene delivery, part 1:: Synthesis of and binding studies with biotinylated cluster glycosides containing N-acetylgalactosamine

Westerlind U; Westman J; Törnquist E; Smith CIE; Oscarson S; Lahmann M; Norberg T
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;105(2):266-273

Reduction in serum levels of antimitochondrial (M2) antibodies following immunoglobulin therapy in severe combined immunodeficient (SCID) mice reconstituted with lymphocytes from patients with primary biliary cirrhosis (PBC)

Abedi MR; Hammarstrom L; Broome U; Angelin B; Smith CIE; Christensson B
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;108(3):490-496

Differential susceptibility to Mycoplasma pulmonis intranasal infection in X-linked immunodeficient (XID), severe combined immunodeficient (SCID), and immunocompetent mice

Sandstedt K; Berglof A; Feinstein R; Bolske G; Evengard B; Smith CIE
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;106(3):509-517

Studies of the molecular basis of IgA production, subclass regulation and class-switch recombination in IgA nephropathy patients

Baskin B; Pettersson E; Rekola S; Smith CIE; Islam KB
Article: EMBO JOURNAL. 2003;22(18):4616-4624

Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering

Márquez JA; Smith CIE; Petoukhov MV; Lo Surdo P; Mattsson PT; Knekt M; Westlund A; Scheffzek K; Saraste M; Svergun DI
Article: LEUKEMIA. 2003;17(9):1880-1890

High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma

Islam TC; Asplund AC; Lindvall JM; Nygren L; Liden J; Kimby E; Christensson B; Smith CIE; Sander B
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2003;1645(2):123-132

Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases

Nore BF; Mattsson PT; Antonsson P; Bäckesjö CM; Westlund A; Lennartsson J; Hansson H; Löw P; Rönnstrand L; Smith CIE
Article: BRIEFINGS IN BIOINFORMATICS. 2003;4(4):315-324

In silico tools for signal transduction research.

Lindvall JM; Blomberg KEM; Smith CIE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;299(3):510-515

Phosphorylation of Bruton's tyrosine kinase by c-Abl

Bäckesjö CM; Vargas L; Superti-Furga G; Smith CIE
Article: JOURNAL OF CLINICAL INVESTIGATION. 2002;110(7):1029-1035

Clinical and molecular analysis of patients with defects in μ heavy chain gene

Granados EL; Porpiglia AS; Hogan MB; Matamoros N; Krasovec S; Pignata C; Smith CIE; Hammarstrom L; Bjorkander J; Belohradsky BH; Casariego GF; Rodriguez MCG; Conley ME
Article: FEBS LETTERS. 2002;527(1-3):274-278

Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)

Heinonen JE; Smith CIE; Nore BF
Article: CLINICAL IMMUNOLOGY. 2002;104(3):237-241

Express subcutaneous IgG infusions: Decreased time of delivery with maintained safety

Hansen S; Gustafson R; Smith CIE; Gardulf A
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2002;32(4):982-993

Expression profiling in transformed human B cells:: influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays

Islam TC; Lindvall J; Wennborg A; Brandén LJ; Rabbani H; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(11):9351-9357

Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx

Vargas L; Nore BF; Berglöf A; Heinonen JE; Mattsson PT; Smith CIE; Mohamed AJ
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;112(1):44-47

Characterization of the CDR3 region of rearranged α heavy chain genes in human fetal liver

Baskin B; Islam KB; Smith CIE
Article: FEBS LETTERS. 2001;508(1):11-15

Both proline-rich sequences in the TH region of Bruton's tyrosine kinase stabilize intermolecular interactions with the SH3 domain

Hansson H; Smith CIE; Härd T
Article: IMMUNOGENETICS. 2001;53(7):550-556

Variations in the human phospholipase Cγ2 gene in patients with B-cell defects of unknown etiology

Wang DM; Boylin EC; Minegishi Y; Wen RR; Smith CIE; Ihle JN; Conley ME
Article: GENE THERAPY. 2001;8(14):1051-1056

Mapping of herpes simplex virus-1 VP22 functional domains for inter- and subcellular protein targeting

Aints A; Güven H; Gahrton G; Smith CIE; Dilber MS
Article: JOURNAL OF PEDIATRICS. 2001;139(1):148-151

A mutation in Bruton's tyrosine kinase as a cause of selective anti-polysaccharide antibody deficiency

Wood PMD; Mayne A; Joyce H; Smith CIE; Granoff DM; Kumararatne DS
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2001;101(3):209-212

Microphthalmia, facial anomalies, microcephaly, thumb and hallux hypoplasia, and agammaglobulinemia

Verloes A; Dresse MF; Keutgen H; Asplund C; Smith CIE
Article: CYTOKINE. 2001;14(3):136-142

Expression and release of stable and active forms of murine granulocyte-macrphage colony-stimulating factor (mGM-CSF) targeted to different subcellular compartments

Arteaga HJ; Mohamed AJ; Christensson B; Gahrton G; Smith CIE; Dilber MS
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2001;67(1):20-26

Proximal promoter of the murine syndecan-1 gene is not sufficient for the developmental pattern of syndecan expression in B lineage cells

Volpe CP; Lundgren A; Aints A; Mohamed AJ; Jaakkola P; Christensson B; Gahrton G; Jalkanen M; Smith CIE; Dilber MS
Article: PEDIATRICS. 2001;107(4):E48

High levels of interferon gamma in the plasma of children with complete interferon gamma receptor deficiency

Fieschi C; Dupuis S; Picard C; Smith CIE; Holland SM; Casanova JL
Article: LAKARTIDNINGEN. 2001;98(9):924-926

[Gene therapy is probably going to fulfil expectations. Not yet a risk-free therapeutic method].

Smith CI
Article: FEBS LETTERS. 2001;489(1):67-70

Intermolecular interactions between the SH3 domain and the proline-rich TH region of Bruton's tyrosine kinase

Hansson H; Okoh MP; Smith CIE; Vihinen M; Härd T
Article: GENE THERAPY. 2001;8(1):84-87

In vivo nuclear delivery of oligonucleotides via hybridizing bifunctional peptides

Brandén LJ; Christensson B; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(51):40614-40619

Nucleocytoplasmic shuttling of Bruton's tyrosine kinase

Mohamed AJ; Vargas L; Nore BF; Bäckesjo CM; Christenssonn B; Smith CIE
Article: PROTEIN EXPRESSION AND PURIFICATION. 2000;20(3):365-371

Rational design and purification of human Bruton's tyrosine kinase SH3-SH2 protein for structure-function studies

Nera KP; Brockmann E; Vihinen M; Smith CIE; Mattsson PT
Article: JOURNAL OF GENE MEDICINE. 2000;2(3):204-209

BTK mediated apoptosis, a possible mechanism for failure to generate high titer retroviral producer clones

Islam TC; Brandén LJ; Kohn DB; Islam KB; Smith CIE
Article: JOURNAL OF IMMUNOLOGY. 2000;164(8):4170-4177

Six X-linked agammaglobulinemia-causing missense mutations in the src homology 2 domain of Bruton's tyrosine kinase:: Phosphotyrosine-binding and circular dichroism analysis

Mattsson PT; Lappalainen I; Bäckesjö CM; Brockmann E; Laurén S; Vihinen M; Smith CIE
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(1):145-154

Redistribution of Bruton's tyrosine kinase by activation of phosphatidylinositol 3-kinase and Rho-family GTPases

Nore BF; Vargas L; Mohamed AJ; Brandén LJ; Bäckesjö CM; Islam TC; Mattsson PT; Hultenby K; Christensson B; Smith CIE
Article: IN VIVO. 1999;13(6):439-444

Susceptibility to polyoma virus tumorigenesis in X-linked immunodeficient (XID) and B-cell deficient (μMT) mice is not increased

Heidari S; Berke Z; Berglöf A; Woldegiorgis A; Smith CIE; Dalianis T
Article: NATURE BIOTECHNOLOGY. 1999;17(8):784-787

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA

Brandén LJ; Mohamed AJ; Smith CIE
Article: JOURNAL OF GENE MEDICINE. 1999;1(4):275-279

Intercellular spread of GFP-VP22

Aints A; Dilber MS; Smith CIE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;259(2):364-369

Synergistic activation of the human Btk promoter by transcription factors Sp1/3 and PU.1

Müller S; Maas A; Islam TC; Sideras P; Suske G; Philipsen S; Xanthopoulos KG; Hendriks RW; Smith CIE
Article: JOURNAL OF PEDIATRICS. 1999;134(5):589-596

Early and prolonged intravenous immunoglobulin replacement therapy in childhood agammaglobulinemia:: A retrospective survey of 31 patients

Quartier P; Debré M; De Blic J; de Sauverzac R; Sayegh N; Jabado N; Haddad E; Blanche S; Casanova JL; Smith CIE; Le Deist F; de Saint Basille G; Fischer A
Article: GENE THERAPY. 1999;6(1):12-21

Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22

Dilber MS; Phelan A; Aints A; Mohamed AJ; Elliott G; Smith CIE; O'Hare P
Article: HUMAN MUTATION. 1999;13(4):280-285

Mutations of the human BTK gene coding for Bruton tyrosine kinase in X-linked agammaglobulinemia

Vihinen M; Kwan SP; Lester T; Ochs HD; Resnick I; Väliaho J; Conley ME; Smith CIE
Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 1998;31(3):309-319

Thermal unfolding of small proteins with SH3 domain folding pattern

Knapp S; Mattson PT; Christova P; Berndt KD; Karshikoff A; Vihinen M; Smith CIE; Ladenstein R
Article: BIOCHEMISTRY. 1998;37(9):2912-2924

Solution structure of the SH3 domain from Bruton's tyrosine kinase

Hansson H; Mattsson PT; Allard P; Haapaniemi P; Vihinen M; Smith CIE; Härd T
Article: PEDIATRICS. 1998;101(2):276-284

Mutation screening of the BTK gene in 56 families with X-linked agammaglobulinemia (XLA):: 47 unique mutations without correlation to clinical course

Holinski-Feder E; Weiss M; Brandau O; Jedele KB; Nore B; Bäckesjö CM; Vihinen M; Hubbard SR; Belohradsky BH; Smith CIE; Meindl A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1998;242(2):351-356

Interactions between SH2 and SH3 domains

Vihinen M; Smith CIE
Article: NUCLEIC ACIDS RESEARCH. 1998;26(1):242-247

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

Vihinen M; Brandau O; Brandén LJ; Kwan SP; Lappalainen I; Lester T; Noordzij JG; Ochs HD; Ollila J; Pienaar SM; Riikonen P; Saha BK; Smith CIE
Article: FEBS LETTERS. 1997;413(2):205-210

Missense mutations affecting a conserved cysteine pair in the TH domain of Btk

Vihinen M; Nore BF; Mattsson PT; Backesjo CM; Nars M; Koutaniemi S; Watanabe C; Lester T; Jones A; Ochs HD; Smith CIE
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(8):2118-2121

B cell-deficient mu MT mice as an experimental model for Mycoplasma infections in X-linked agammaglobulinemia

Berglof A; Sandstedt K; Feinstein R; Bolske G; Smith CIE
Article: INTERNATIONAL JOURNAL OF CANCER. 1997;71(4):624-629

Preventive effect of IgG from EBV-seropositive donors on the development of human lympho-proliferative disease in SCID mice

Abedi MR; Linde A; Christensson B; Mackett M; Hammarstrom L; Smith CE
Article: CANCER RESEARCH. 1997;57(8):1523-1528

Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo

Dilber MS; Abedi MR; Christensson B; Bjorkstrand B; Kidder GM; Naus CCG; Gahrton G; Smith CIE
Article: HUMAN MUTATION. 1997;9(5):418-425

Mutation pattern in Bruton's tyrosine kinase gene in 26 unrelated patients with X-linked agammaglobulinemia

Vorechovsky I; Luo LP; Hertz JM; Froland SS; Klemola T; Fiorini M; Quinti I; Paganelli R; Ozsahin H; Hammarstrom L; Webster ADB; Smith CIE
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(1):130-135

Direct and sequential switching from mu to epsilon in patients with Schistosoma mansoni infection and atopic dermatitis

Baskin B; Islam KB; Evengard B; Emtestam L; Smith CIE
Article: NUCLEIC ACIDS RESEARCH. 1997;25(1):166-171

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

Vihinen M; Belohradsky BH; Haire RN; HolinskiFeder E; Kwan SP; Lappalainen I; Lehvaslaiho H; Lester T; Meindl A; Ochs HD; Ollila J; Vorechovsky I; Weiss M; Smith CIE
Article: IMMUNOGENETICS. 1996;45(2):136-141

Duplications and deletions of the human IGHC locus: Evolutionary implications

Rabbani H; Pan Q; Kondo N; Smith CIE; Hammarstrom L
Article: EMBO JOURNAL. 1996;15(22):6241-6250

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase

Salim K; Bottomley MJ; Querfurth E; Zvelebil MJ; Gout I; Scaife R; Margolis RL; Gigg R; Smith CIE; Driscoll PC; Waterfield MD; Panayotou G
Article: ONCOGENE. 1996;13(9):1955-1964

Cell specific expression of human Bruton's agammaglobulinemia tyrosine kinase gene (Btk) is regulated by Sp1- and Spi-1/PU.1-family members

Muller S; Sideras P; Smith CE; Xanthopoulos KG
Article: TRENDS IN IMMUNOLOGY. 1996;17(11):511-516

CD40Lbase: A database of CD40L gene mutations causing X-linked hyper-IgM syndrome

Notarangelo LD; Peitsch MC; Abrahamsen TG; Bachelot C; Bordigoni P; Cant AJ; Chapel H; Clementi M; Deacock S; de Saint Basile G; Duse M; Espanol T; Etzioni A; Fasth A; Fischer A; Giliani S; Gomez L; Hammarstorm L; Jones A; Kanariou M; Kinnon C; Klemola T; Kroczek RA; Levy J; Matamoros N; Monafo V; Paolucci P; Reznick I; Sanal O; Smith CIE; Thompson RA; Tovo P; Villa A; Vihinen M; Vossen J; Zegers BJ
Article: TRENDS IN IMMUNOLOGY. 1996;17(11):502-506

BTKbase: XLA-mutation registry

Vihinen M; Brooimans RA; Kwan SP; Lehväslaiho H; Litman GW; Ochs HD; Resnick I; Schwaber JH; Vorchovsky I; Smith CIE
Article: TRENDS IN IMMUNOLOGY. 1996;17(11):495-496

Immunodeficiency mutation databases - A new research tool

Smith CIE; Vihinen M
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1996;184(4):1243-1249

Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease

Leusen JHW; deKlein A; Hilarius PM; Ahlin A; Palmblad J; Smith CIE; Diekmann D; Hall A; Verhoeven AJ; Roos D
Article: BLOOD. 1996;88(6):2192-2200

Suicide gene therapy for plasma cell tumors

Dilber MS; Abedi MR; Bjorkstrand B; Christensson B; Gahrton G; Xanthopoulos KG; Smith CIE
Article: GENOMICS. 1996;35(3):633-635

A human homologue of the rat rab geranylgeranyl transferase beta subunit on chromosome 1p22-p31

Sanders R; BinIslam K; Betz R; Larsson C; Smith CIE
Article: BRITISH JOURNAL OF HAEMATOLOGY. 1996;92(3):647-652

Bcl-2 rearrangements with breakpoints in both vcr and mbr in non-Hodgkin's lymphomas and chronic lymphocytic leukaemia

Merup M; Spasokoukotskaja T; Einhorn S; Smith CIE; Gahrton G; Juliusson G
Article: SCANDINAVIAN JOURNAL OF LABORATORY ANIMAL SCIENCE. 1996;23(4):171-176

Experimental Campylobacter jejuni infection of scid mice

Berglof A; Feinstein R; Smith CIE; RiesenfeldOrn I; Sandstedt K
Article: NUCLEIC ACIDS RESEARCH. 1996;24(1):160-165

BTKbase, mutation database for X-linked agammaglobulinemia (XLA)

Vihinen M; Iwata T; Kinnon C; Kwan SP; Ochs HD; Vorechovsky I; Smith CIE
Article: ACTA PAEDIATRICA. 1995;84(12):1386-1394

Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden

Ahlin A; DeBoer M; Roos D; Leusen J; Smith CIE; Sundin U; Rabbani H; Palmblad J; Elinder G
Article: HUMAN MOLECULAR GENETICS. 1995;4(12):2403-2405

IMPROVED OLIGONUCLEOTIDE PRIMER SET FOR MOLECULAR DIAGNOSIS OF X-LINKED AGAMMAGLOBULINEMIA - PREDOMINANCE OF AMINO-ACID SUBSTITUTIONS IN THE CATALYTIC DOMAIN OF BRUTONS TYROSINE KINASE

VORECHOVSKY I; LUO LP; DESAINTBASILE G; HAMMARSTROM L; WEBSTER ADB; SMITH CIE
Article: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. 1995;77(2):185-192

FAMILY AND LINKAGE STUDY OF SELECTIVE IGA DEFICIENCY AND COMMON VARIABLE IMMUNODEFICIENCY

VORECHOVSKY I; ZETTERQUIST H; PAGANELLI R; KOSKINEN S; WEBSTER ADB; BJORKANDER J; SMITH CIE; HAMMARSTROM L
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1995;55(5):302-306

RETROVIRAL-MEDIATED GENE-TRANSFER INTO HUMAN BONE-MARROW STROMAL CELLS - STUDIES OF EFFICIENCY AND IN-VIVO SURVIVAL IN SCID MICE

LI KJ; DILBER MS; ABEDI MR; BJORKSTRAND B; SMITH CIE; GAROFF H; GAHRTON G; XANTHOPOULOS KG
Article: TRENDS IN IMMUNOLOGY. 1995;16(10):460-465

BTKBASE - A DATABASE OF XLA-CAUSING MUTATIONS

VIHINEN M; COOPER MD; DESAINTBASILE G; FISCHER A; GOOD RA; HENDRIKS RW; KINNON C; KWAN SP; LITMAN GW; NOTARANGELO LD; OCHS HD; ROSEN FS; VETRIE D; WEBSTER ADB; ZEGERS BJM; SMITH CIE
Article: JOURNAL OF ADVANCED NURSING. 1995;21(5):917-927

LIFELONG TREATMENT WITH GAMMA-GLOBULIN FOR PRIMARY ANTIBODY DEFICIENCIES - THE PATIENTS EXPERIENCES OF SUBCUTANEOUS SELF-INFUSIONS AND HOME THERAPY

GARDULF A; BJORVELL H; ANDERSEN V; BJORKANDER J; ERICSON D; FROLAND SS; GUSTAFSON R; HAMMARSTROM L; NYSTROM T; SOEBERG B; SMITH CIE
Article: HUMAN MOLECULAR GENETICS. 1995;4(4):693-700

IDENTIFICATION OF BTK MUTATIONS IN 20 UNRELATED PATIENTS WITH X-LINKED AGAMMAGLOBULINEMIA (XLA)

JIN H; WEBSTER ADB; VIHINEN M; SIDERAS P; VORECHOVSKY I; HAMMARSTROM L; BERNATOWSKAMATUSZKIEWICZ E; SMITH CIE; BOBROW M; VETRIE D
Article: LANCET. 1995;345(8946):365-369

SUBCUTANEOUS IMMUNOGLOBULIN REPLACEMENT IN PATIENTS WITH PRIMARY ANTIBODY DEFICIENCIES - SAFETY AND COSTS

GARDULF A; ANDERSEN V; BJORKANDER J; ERICSON D; FROLAND SS; GUSTAFSON R; HAMMARSTROM L; JACOBSEN MB; JONSSON E; MOLLER G; NYSTROM T; SOEBERG B; SMITH CIE
Article: BIOCHEMISTRY. 1995;34(5):1475-1481

STRUCTURAL BASIS FOR PLECKSTRIN HOMOLOGY DOMAIN MUTATIONS IN X-LINKED AGAMMAGLOBULINEMIA

VIHINEN M; ZVELEBIL M; ZHU QL; BROOIMANS RA; OCHS HD; ZEGERS BJM; NILSSON L; WATERFIELD MD; SMITH CIE
Article: JOURNAL OF IMMUNOLOGY. 1995;154(3):1265-1272

MOLECULAR-CLONING, CHARACTERIZATION, AND CHROMOSOMAL LOCALIZATION OF A HUMAN LYMPHOID TYROSINE KINASE RELATED TO MURINE BLK

ISLAM KB; RABBANI H; LARSSON C; SANDERS R; SMITH CIE
Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1995;371A:685-690

Biological properties of yolk immunoglobulins.

Janson AK; Smith CI; Hammarström L
Article: HUMAN MOLECULAR GENETICS. 1995;4(1):51-58

DNA-BASED MUTATION ANALYSIS OF BRUTONS TYROSINE KINASE GENE IN PATIENTS WITH X-LINKED AGAMMAGLOBULINEMIA

VORECHOVSKY I; VIHINEN M; DESAINTBASILE G; HONSOVA S; HAMMARSTROM L; MULLER S; NILSSON L; FISCHER A; SMITH CIE
Visa fler

Alla övriga publikationer

Letter: EUROPEAN JOURNAL OF HAEMATOLOGY. 2024;113(1):130-131

Reduced clone size upon BTK inhibitor resistance mutations relates to toxicity caused by inherited PLCG2 gain-of-function variations

Smith CIE; Zain R
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(4):e13153

Do reduced numbers of plasmacytoid dendritic cells contribute to the aggressive clinical course of COVID-19 in chronic lymphocytic leukaemia?

Smith CIE; Zain R; osterborg A; Palma M; Buggert M; Bergman P; Bryceson Y
Editorial comment: FRONTIERS IN IMMUNOLOGY. 2021;12:804735

New Insights on Bruton's Tyrosine Kinase Inhibitors

Smith CIE; Brown JR; Zain R
Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:630942

Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects

Estupinan HY; Berglof A; Zain R; Smith CIE
Review: FRONTIERS IN IMMUNOLOGY. 2021;12:689472

Resistance Mutations to BTK Inhibitors Originate From the NF-κB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway

Smith CIE; Burger JA
Review: NEUROTHERAPEUTICS. 2019;16(2):248-262

Targeted Oligonucleotides for Treating Neurodegenerative Tandem Repeat Diseases

Zain R; Smith CIE
Review: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. 2019;59:605-630

Therapeutic Oligonucleotides: State of the Art

Smith CIE; Zain R
Letter: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2018;29(4):453-456

Kappa-deleting recombination excision circle levels remain low or undetectable throughout life in patients with X-linked agammaglobulinemia

King J; Borte S; Brodszki N; von Dobeln U; Smith CIE; Hammarstrom L
Editorial comment: ONCOTARGET. 2017;8(66):109857-109858

Terminating B cell receptor signaling

Mohammad DK; Nore BF; Smith CIE
Published conference paper: HUMAN VACCINES & IMMUNOTHERAPEUTICS. 2017;13(12):2849-2858

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses

Stenler S; Lundin KE; Hansen L; Petkov S; Mozafari N; Isaguliants M; Blomberg P; Smith CIE; Goldenberg DM; Chang C-H; Ljungberg K; Hinkula J; Wahren B
Review: SEMINARS IN CANCER BIOLOGY. 2017;45:36-49

Enigmas in tumor resistance to kinase inhibitors and calculation of the drug resistance index for cancer (DRIC)

Smith CIE
Review: ONCOGENE. 2017;36(15):2045-2053

From identification of the BTK kinase to effective management of leukemia

Smith CIE
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2015;82(3):208-217

Targets for Ibrutinib Beyond B Cell Malignancies

Berglof A; Hamasy A; Meinke S; Palma M; Krstic A; Mansson R; Kimby E; Osterborg A; Smith CIE
Review: HUMAN GENE THERAPY. 2015;26(8):475-485

Oligonucleotide Therapies: The Past and the Present

Lundin KE; Gissberg O; Smith CIE
Review: CURRENT ALLERGY AND ASTHMA REPORTS. 2015;15(3):510

Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia

Bestas B; Turunen JJ; Blomberg KEM; Wang Q; Mansson R; Andaloussi SEL; Berglof A; Smith CIE
Editorial comment: HUMAN VACCINES & IMMUNOTHERAPEUTICS. 2014;10(5):1306-1308

Safety and efficacy of DNA vaccines Plasmids vs. minicircles

Stenler S; Blomberg P; Smith CIE
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2013;9(12):1205-1221

Agammaglobulinemia: causative mutations and their implications for novel therapies

Berglof A; Turunen JJ; Gissberg O; Bestas B; Blomberg KEM; Smith CIE
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2013;78(2):130-139

Inhibitors of BTK and ITK: State of the New Drugs for Cancer, Autoimmunity and Inflammatory Diseases

Vargas L; Hamasy A; Nore BF; Smith CIE
Review: ADVANCES IN GENETICS, VOL 107. 2013;82:47-107

Biological Activity and Biotechnological Aspects of Locked Nucleic Acids

Lundin KE; Hojland T; Hansen BR; Persson R; Bramsen JB; Kjems J; Koch T; Wengel J; Smith CIE
Other: JOURNAL OF IMMUNOLOGY. 2012;188(7):2948-2955

The gene involved in X-linked agammaglobulinaemia is member of the src family of protein-tyrosine kinases (Reprinted from Nature, vol 391, pg 226, 1993)

Vetrie D; Vorechovsky I; Sideras P; Holland J; Davies A; Flinter F; Hammarstrom L; Kinnon C; Levinsky R; Bobrow M; Smith CIE; Bentley DR
Editorial comment: FEBS JOURNAL. 2011;278(12):1969

Tec family kinases

Yu L; Smith CIE
Review: FEBS JOURNAL. 2011;278(12):2001-2010

TEC family kinases in health and disease - loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK

Hussain A; Yu L; Faryal R; Mohammad DK; Mohamed AJ; Smith CIE
Review: EXPERT OPINION ON DRUG DELIVERY. 2010;7(6):721-735

Non-viral nanovectors for gene delivery: factors that govern successful therapeutics

Viola JR; El-Andaloussi S; Oprea II; Smith CIE
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;123(5):1170-1173.e3

Clinical and genetic diagnosis of warts, hypogammaglobulinemia, infections, and myelokathexis syndrome in 10 patients

Tassone L; Notarangelo LD; Bonomi V; Savoldi G; Savoldi A; Soresina A; Smith CIE; Porta F; Plebani A; Notarangelo LD; Badolato R
Review: ADVANCES IN GENETICS, VOL 107. 2008;64:51-80

Phylogeny of Tec Family Kinases: Identification of a Premetazoan Origin of Btk, Bmx, Itk, Tec, Txk, and the Btk Regulator SH3BP5

Ortutay C; Nore BF; Vihinen M; Smith CIE
Other: IMMUNOLOGICAL REVIEWS. 2008;224:5-6

Goran!Moller, MD, PhD, 1936-2008 -: Obituary

Smith CIE; Hammarstrom L
Published conference paper: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 2007;26(10-12):1501-1504

Evaluating coupling procedures for synthesis of LNA-peptide conjugates

Steunenberg P; Leijonmarck H; Svahn MG; Smith CIE; Stroemberg R
Review: CURRENT MOLECULAR MEDICINE. 2007;7(6):555-566

Gene expression signatures in primary immunodeficiencies: The experience from human disease and mouse models

Emelie K; Blomberg M; Smith CIE; Lindvall JM
Meeting abstract: CYTOKINE. 2007;39(1):14

Potential role of Bruton's tyrosine kinase in toll-like receptor 9 mediated cytokine production from B cells

Hasan M; Lopez-Herrera G; Blomberg EM; Berglof A; Smith CIE; Vargas L
Review: ADVANCES IN GENETICS, VOL 107. 2006;56:1-51

Biological activity and biotechnological aspects of peptide nucleic acid

Lundin KE; Good L; Stromberg R; Graslund A; Smith CIE
Review: CURRENT PHARMACEUTICAL DESIGN. 2005;11(28):3671-3680

Bioplex technology:: Novel synthetic gene delivery pharmaceutical based on peptides anchored to nucleic acids

Simonson OE; Svahn MG; Törnquist E; Lundin KE; Smith CIE
Review: IMMUNOLOGICAL REVIEWS. 2005;203:200-215

Bruton's tyrosine kinase:: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling

Lindvall JM; Blomberg KEM; Väliaho J; Vargas L; Heinonen JE; Berglöf A; Mohamed AJ; Nore BF; Vihinen M; Smith CIE
Published conference paper: JOURNAL OF GENE MEDICINE. 2004;6:S36-S44

Adding functional entities to plasmids

Svahn MG; Lundin KE; Ge R; Törnquist E; Simonson EO; Oscarsson S; Leijon M; Brandén LJ; Smith CIE
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2003;3(6):941-949

Gene therapy of monogenic and cardiovascular disorders

Blomberg P; Smith CIE
Letter: NATURE BIOTECHNOLOGY. 2003;21(3):230-231

Choosing CCR5 or Rev siRNA in HIV-1

Arteaga HJ; Hinkula J; van Dijk-Härd I; Dilber MS; Wahren B; Christensson B; Mohamed AJ; Smith CIE
Corrigendum: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;301(1):258

Phosphorylation of Bruton's tyrosine kinase by c-Abl (vol 299, pg 510, 2002)

Bäckesjö CM; Vargas L; Superti-Furga G; Smith CIE
Editorial comment: EMBO REPORTS. 2002;3(6):516-520

Disease models for every field

Smith CIE
Review: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2002;346:106-124

Bioplex technology:: Novel synthetic gene delivery system based on peptides anchored to nucleic acids

Brandén LJ; Smith CIE
Review: BIOESSAYS. 2001;23(5):436-446

The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species

Smith CIE; Islam TC; Mattsson PT; Mohamed AJ; Nore BF; Vihinen M
Review: ADVANCES IN GENETICS, VOL 107. 2001;43:103-188

Primary immunodeficiency mutation databases

Vihinen M; Arredondo-Vega FX; Casanova JL; Etzioni A; Giliani S; Hammarström L; Hershfield MS; Heyworth PG; Hsu AP; Lähdesmäki A; Lappalainen I; Notarangelo LD; Puck JM; Reith W; Roos D; Schumacher RF; Schwarz K; Vezzoni P; Villa A; Väliaho J; Smith CIE
Review: FRONTIERS IN BIOSCIENCE - LANDMARK. 2000;5:D917-D928

Bruton tyrosine kinase (Btk) in X-linked agammaglobulinemia (XLA)

Vihinen M; Mattsson PT; Smith CIE
Review: IMMUNOLOGICAL REVIEWS. 2000;178:5-7

Experiments of nature: primary immune defects deciphered and defeated

Smith CIE
Review: IMMUNOLOGICAL REVIEWS. 2000;178:49-63

The cellular phenotype conditions Btk for cell survival or apoptosis signaling

Islam TC; Smith CIE
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):S219

Atypical btk deficiency presenting with selective polysaccharide antibody deficiency in the presence of normal serum immunoglobulins

Wood P; Smith E; Hazelwood M; Joyce H; Granoff D; Kumararatne D
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1999;49(2):113-118

Signalling of Bruton's tyrosine kinase, Btk

Mohamed AJ; Nore BF; Christensson B; Smith CIE
Review: SEMINARS IN IMMUNOPATHOLOGY. 1998;19(4):369-381

X-linked agammaglobulinemia:: lack of mature B lineage cells caused by mutations in the Btk kinase

Smith CIE; Bäckesjö CM; Berglöf A; Brandén LJ; Islam T; Mattsson PT; Mohamed AJ; Müller S; Nore B; Vihinen M
Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1998;451:493-497

Gene marking and gene therapy in multiple myeloma

Gahrton G; Björkstrand B; Dilber MS; Sundman-Engberg B; Ljungman P; Smith CIE
Published conference paper: ANNALS OF MEDICINE. 1997;29(6):579-583

An academic centre for gene therapy research with clinical grade manufacturing capability

Islam KB; Blomberg P; Wikström K; Smith CIE
Editorial comment: GENE THERAPY. 1997;4(4):273-274

Suicide genes and bystander killing: Local and distant effects

Dilber MS; Smith CIE
Review: ADVANCES IN GENETICS, VOL 107. 1997;35:57-115

Molecular basis for X-linked immunodeficiencies

Smith CIE; Notarangelo LD
Review: HUMAN MUTATION. 1997;10(4):261-267

Registries of immunodeficiency patients and mutations

Lappalainen I; Ollila J; Smith CIE; Vihinen M
Review: MEDICINE. 1996;75(6):287-299

X-linked agammaglobulinemia - A clinical and molecular analysis

Ochs HD; Smith CIE
Review: BIOESSAYS. 1996;18(10):825-834

X-linked agammaglobulinemia (XLA): A genetic tyrosine kinase (Btk) disease

Mattsson PT; Vihinen M; Smith CIE
Review: LAKARTIDNINGEN. 1996;93(5):349-350

[Gene therapy. Expectations and realization].

Smith E
Review: CRITICAL REVIEWS IN IMMUNOLOGY. 1996;16(3):251-275

Structural aspects of signal transduction in B-cells

Vihinen M; Smith CIE
Review: APMIS. 1995;103(12):833-842

Genetics of IgA deficiency

Truedsson L; Baskin B; Pan Q; Rabbani H; Vorechovsky I; Smith CIE; Hammarstrom L
Published conference paper: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. 1995;76(3):S214-S218

THE INFLUENCE OF GENE DELETIONS AND DUPLICATIONS WITHIN THE IGHC LOCUS ON SERUM IMMUNOGLOBULIN SUBCLASS LEVELS

RABBANI H; KONDO N; SMITH CIE; HAMMARSTROM L
Published conference paper: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. 1995;76(3):S198-S202

STRUCTURAL BASIS FOR X-LINKED AGAMMAGLOBULINEMIA (XLA) - MUTATIONS AT INTERACTING BTK RESIDUES R562, W563, AND A582

MANIAR HS; VIHINEN M; WEBSTER ADB; NILSSON L; SMITH CIE
Editorial comment: ANNALS OF MEDICINE. 1995;27(4):477-479

POSITIONAL CLONING AND THE MOLECULAR-BASIS OF IMMUNODEFICIENCY

SMITH CIE; HAMMARSTROM L
Review: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1995;371A:9-13

In vivo switching: identification of germline transcripts for human IgA.

Smith CI; Baskin B; Pattersson E; Hammarstrom L; Islam KB
Other: IMMUNOGENETICS. 1995;42(2):149-152

THE PAX5 GENE - A LINKAGE AND MUTATION ANALYSIS IN CANDIDATE HUMAN PRIMARY IMMUNODEFICIENCIES

VORECHOVSKY I; KOSKINEN S; PAGANELLI R; SMITH CIE; BUSSLINGER M; HAMMARSTROM L
Review: ADVANCES IN IMMUNOLOGY, VOL 150. 1995;59:135-223

MOLECULAR AND CELLULAR ASPECTS OF X-LINKED AGAMMAGLOBULINEMIA

SIDERAS P; SMITH CIE
Review: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 1995;27(4):303-313

CHARACTERIZATION OF HAEMOPHILUS-INFLUENZAE ISOLATES FROM THE RESPIRATORY-TRACT OF PATIENTS WITH PRIMARY ANTIBODY DEFICIENCIES - EVIDENCE FOR PERSISTENT COLONIZATIONS

SAMUELSON A; BORRELLI S; GUSTAFSON R; HAMMARSTROM L; SMITH CIE; JONASSON J; LINDBERG AA
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