Christina Hultman
Professor Emeritus/Emerita | Docent
E-postadress: christina.hultman@ki.se
Telefon: +46852482475
Besöksadress: Nobels väg 12a, 17165 Solna
Postadress: C8 Medicinsk epidemiologi och biostatistik, C8 Administration, 171 77 Stockholm
Om mig
- Jag har över 35 års erfarenhet som kliniker i psykiatrivården och bedriver som forskare longitudinella fall-kontrollstudier inom schizofreni. 2009 blev jag professor i psykiatrisk epidemiologi vid Karolinska Institutet. Läs mer om min forskning på den engelska profilsidan.
Utbildning/specialisering:
1979 Psych.D./M.Sc, Psychology
1996 Specialist in Clinical Psychology
1996 Specialist in Clinical Research
1996 Licenced Psychotherapist
Doktorsgrad:
1996 Ph.D. Uppsala University - Clinical Psychology/Psychiatry
- Thesis: Obstetric complications, Electrodermal Activity and Psychosocial Factors within a Stress-Vulnerability Model of Schizophrenia. Supervisor: Professor Arne Öhman, Karolinska Institutet (KI).
Forskningsbeskrivning
- Urval av originalartiklar:
1. De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Cicek AE, et al. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature. 2014 - 515(7526):209-15.
2. Genovese G, Kähler AK, Handsaker RE, Lindberg J, Rose SA, Bakhoum SF, et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. New England Journal of Medicine. 2014 - 371(26):2477-87.
3. Hultman CM, Geddes J, Sparén P, Takei N, Murray RM, Cnattingius S. PapersPrenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control studyPrenatal and perinatal risk factors for early onset schizophrenia, affective psychosis, and reactive psychosis. Bmj. 1999 - 318(7181):421-6.
4. Hultman CM, Sparén P, Cnattingius S. Perinatal risk factors for infantile autism. Epidemiology. 2002 - 13(4):417-23.
5. Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, et al. Analysis of protein-coding genetic variation in 60, 706 humans. Nature. 2016 - 536(7616):285-91.
6 .Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. The Lancet. 2009 - 373(9659):234-9.
7. Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P, et al. A polygenic burden of rare disruptive mutations in schizophrenia. Nature. 2014 - 506(7487):185-90.
8. Purcell SM, Wray NR, Stone JL, Visscher PM, O'donovan MC, Sullivan PF, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009 - 460(7256):748-52.
9. Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature genetics. 2013 - 45(10):1150-9.
10. Stone JL, O’Donovan MC, Gurling H, Kirov GK, Blackwood DH, Corvin A, et al. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature. 2008 - 455(7210):237-41.
Undervisning
- Huvudhandledning av doktorander:
Viktoria Johansson, Psychiatrist, Department of Medical Epidemiology and Biostatistics, KI, “Cerebrospinal Fluid Biomarkers in Twins with Schizophrenia and Bipolar Disorder”, 2015
Sven Sandin, Biostatistician, Maudsley Hospital at Kings’s College, London, UK. ‘Maternal effects in autism’, 2014
Emma Frans, Biomedical engineer, Department of Medical Epidemiology and Biostatistics, KI, “High paternal age and risk of psychiatric disorders in offspring”, 2013
Anna Svensson, KTH Bioengineer, Department of Medical Epidemiology and Biostatistics, KI, “Family studies of schizophrenia and pregnancy outcomes”, 2009.
Erik Wennström, Psychologist, Dept of Neuroscience, Ulleråker, Uppsala, “The Camberwell Assessment of Need as an outcome measure in community mental health care”, 2008.
James MacCabe, Psychiatrist, Institute of Psychiatry, Psychological Medicine, London, “Educational achievement in schizophrenia and bipolar disorder”, 2007.
Gabriella Stålberg, Psychologist, Department of Neuroscience, Psychiatry, Ulleråker “Early risk factors and family relations in schizophrenia”. Licentiate thesis, 2004/ Doctorate thesis 2013
Postdocs:
Anna Kähler, Institute of Psychiatry, University of Oslo, and Department of Medical Genetics, Oslo University Hospital, Norway, 2010-2014
Jacqueline Borg, Clinical Neuroscience, Karolinska Institutet, 2008-2012
Elin Dianna Gunnarsdottir, University of Akureyri, Iceland, 2008-2009
Unnur Valdimarsdottir, University of Iceland, Reykjavik, Iceland, 2005-2008
Carola Åberg, Stockholm University 2005-2006
Artiklar
- Article: BIOLOGICAL PSYCHIATRY. 2019;86(2):110-119
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2019;28(7):1252-1258
- Article: ACTA PSYCHIATRICA SCANDINAVICA. 2019;139(6):558-571
- Article: NATURE GENETICS. 2019;51(5):793-803
- Article: NATURE GENETICS. 2019;51(4):659-674
- Article: NATURE GENETICS. 2019;51(3):431-444
- Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2019;47(2):260-268
- Article: SCHIZOPHRENIA RESEARCH. 2019;204:183-192
- Article: PSYCHOLOGICAL MEDICINE. 2018;48(16):2710-2716
- Article: TRANSLATIONAL PSYCHIATRY. 2018;8(1):210
- Article: SCHIZOPHRENIA BULLETIN. 2018;44(5):1045-1052
- Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2018;102(6):1204-1211
- Article: SCIENTIFIC REPORTS. 2018;8(1):6915
- Article: PSYCHOLOGICAL MEDICINE. 2018;48(7):1201-1208
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2018;10(436):eaan8292
- Article: BIOLOGICAL PSYCHIATRY. 2018;83(7):589-597
- Article: MOLECULAR PSYCHIATRY. 2018;23(2):400-412
- Article: NEUROPSYCHOPHARMACOLOGY. 2018;43(3):525-533
- Article: CLINICAL EPIDEMIOLOGY. 2018;10:1817-1826
- Article: PLOS ONE. 2018;13(1):e0191153
- Article: PLOS ONE. 2018;13(8):e0202028
- Article: GENOME MEDICINE. 2017;9(1):114
- Article: PSYCHIATRY RESEARCH. 2017;258:9-14
- Article: NATURE COMMUNICATIONS. 2017;8(1):774
- Article: AMERICAN JOURNAL OF MEDICAL GENETICS, PART B: NEUROPSYCHIATRIC GENETICS. 2017;174(7):724-731
- Article: NATURE NEUROSCIENCE. 2017;20(9):1217-1224
- Article: MOLECULAR NEUROBIOLOGY. 2017;54(7):5166-5176
- Article: NATURE. 2017;548(7665):87-91
- Article: NATURE GENETICS. 2017;49(8):1167-1173
- Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2017;267(5):391-402
- Article: NATURE GENETICS. 2017;49(7):978-985
- Article: ACTA ONCOLOGICA. 2017;56(5):746-752
- Article: TWIN RESEARCH AND HUMAN GENETICS. 2017;20(2):108-118
- Article: DEPRESSION AND ANXIETY. 2017;34(2):178-187
- Article: AMERICAN JOURNAL OF MEDICAL GENETICS, PART A. 2017;173(2):395-406
- Article: GENOME BIOLOGY. 2017;18(1):24
- Article: TRANSLATIONAL PSYCHIATRY. 2017;7(1):e993
- Article: PSYCHIATRY RESEARCH. 2017;247:105-112
- Article: NATURE GENETICS. 2017;49(1):27-35
- Article: NATURE NEUROSCIENCE. 2016;19(12):1563-1565
- Article: MOLECULAR NEUROBIOLOGY. 2016;53(10):6608-6619
- Article: DISEASES OF THE ESOPHAGUS. 2016;30(8):1128-1134
- Article: NATURE NEUROSCIENCE. 2016;19(11):1433-1441
- Article: GENETICS. 2016;204(2):711-722
- Article: PSYCHOLOGICAL MEDICINE. 2016;46(14):2981-2988
- Article: MOLECULAR PSYCHIATRY. 2016;21(10):1342-1350
- Article: MOLECULAR PSYCHIATRY. 2016;21(9):1290-1297
- Article: JAMA ONCOLOGY. 2016;2(9):1188-1196
- Article: GENOME BIOLOGY. 2016;17(1):176
- Article: NATURE. 2016;536(7616):285-291
- Article: BIOLOGICAL PSYCHIATRY. 2016;80(4):323-330
- Article: HUMAN MOLECULAR GENETICS. 2016;25(15):3383-3394
- Article: NEUROLOGY. 2016;87(2):192-197
- Article: JAMA PSYCHIATRY. 2016;73(6):590-597
- Article: PSYCHOLOGICAL MEDICINE. 2016;46(7):1497-1507
- Article: MOLECULAR PSYCHIATRY. 2016;21(5):693-700
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2016;45(2):408-416
- Article: NATURE NEUROSCIENCE. 2016;19(4):571-577
- Article: THE LANCET PSYCHIATRY. 2016;3(4):350-357
- Article: INTERNATIONAL JOURNAL OF SOCIAL PSYCHIATRY, THE. 2016;62(2):156-166
- Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 2016;208(2):128-137
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2016;8(322):322ra9
- Article: NEUROPSYCHOLOGY. 2016;30(1):40-52
- Article: GENOME BIOLOGY. 2015;16:291
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2015;44(5):1706-1721
- Article: THE LANCET PSYCHIATRY. 2015;2(9):817-824
- Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2015;39(8):1396-1405
- Article: NATURE COMMUNICATIONS. 2015;6:7213
- Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2015;23(4):555-557
- Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;96(2):283-294
- Article: EUROPEAN CHILD AND ADOLESCENT PSYCHIATRY. 2015;24(2):173-183
- Article: NATURE NEUROSCIENCE. 2015;18(2):199-209
- Article: EUROPEAN PSYCHIATRY. 2015;30(1):8-13
- Article: PSYCHO-ONCOLOGY. 2015;24(1):47-53
- Article: HUMAN GENETICS. 2015;134(1):77-87
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2014;371(26):2477-2487
- Article: MULTIPLE SCLEROSIS JOURNAL. 2014;20(14):1881-1891
- Article: NATURE. 2014;515(7526):209-215
- Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;95(5):535-552
- Article: MOLECULAR PSYCHIATRY. 2014;19(9):1017-1024
- Article: NATURE GENETICS. 2014;46(8):881-885
- Article: NATURE. 2014;511(7510):421-427
- Article: SCHIZOPHRENIA BULLETIN. 2014;40(4):925-935
- Article: MOLECULAR PSYCHIATRY. 2014;19(7):762-773
- Article: HUMAN MOLECULAR GENETICS. 2014;23(12):3316-3326
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2014;311(17):1770-1777
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(16):5968-5973
- Article: MOLECULAR PSYCHIATRY. 2014;19(4):452-461
- Article: HUMAN MOLECULAR GENETICS. 2014;23(6):1669-1676
- Article: HUMAN MOLECULAR GENETICS. 2014;23(5):1175-1185
- Article: JAMA PSYCHIATRY. 2014;71(3):255-264
- Article: INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH. 2014;23(1):62-68
- Article: BIOLOGICAL PSYCHIATRY. 2014;75(5):371-377
- Article: NATURE. 2014;506(7487):185-190
- Article: NORDIC JOURNAL OF PSYCHIATRY. 2014;68(1):38-43
- Article: MOLECULAR PSYCHIATRY. 2014;19(1):37-40
- Article: PSYCHOLOGICAL MEDICINE. 2014;44(1):71-84
- Article: EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY. 2013;4:20650
- Article: JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS. 2013;43(11):2650-2663
- Article: JAMA PSYCHIATRY. 2013;70(11):1224-1230
- Article: MOLECULAR PSYCHIATRY. 2013;18(11):1178-1184
- Article: NATURE GENETICS. 2013;45(10):1150-1159
- Article: NATURE GENETICS. 2013;45(9):984-994
- Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2013;21(9):1007-1011
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2013;310(1):75-84
- Article: JAMA PSYCHIATRY. 2013;70(6):573-581
- Article: SCHIZOPHRENIA RESEARCH. 2013;147(1):140-146
- Article: JAMA PSYCHIATRY. 2013;70(5):516-521
- Article: SCHIZOPHRENIA RESEARCH. 2013;146(1-3):289-290
- Article: BMC BIOINFORMATICS. 2013;14:74
- Article: JAMA PSYCHIATRY. 2013;70(3):253-260
- Article: BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2013;120(4):446-455
- Article: MENOPAUSE. 2013;20(2):146-151
- Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2013;47(1):83-90
- Article: SCHIZOPHRENIA RESEARCH. 2013;143(1):192-197
- Article: PLOS ONE. 2013;8(11):e77975
- Article: PLOS ONE. 2013;8(12):e83101
- Article: EPIGENOMICS. 2012;4(6):605-621
- Article: JOURNAL OF TRAUMATIC STRESS. 2012;25(6):721-727
- Article: ARCHIVES OF GENERAL PSYCHIATRY. 2012;69(11):1099-1103
- Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;91(4):597-607
- Article: BIOINFORMATICS. 2012;28(19):2543-2545
- Article: JOURNAL OF PERSONALITY DISORDERS. 2012;26(5):737-750
- Article: MOLECULAR PSYCHIATRY. 2012;17(10):996-1006
- Article: MOLECULAR PSYCHIATRY. 2012;17(9):880-886
- Article: ANNUAL REVIEW OF ECONOMICS. 2012;4:627-662
- Article: ARCHIVES OF GENERAL PSYCHIATRY. 2012;69(6):610-617
- Article: NATURE GENETICS. 2012;44(6):623-630
- Article: NATURE GENETICS. 2012;44(6):631-U41
- Article: JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY. 2012;51(5):477-486.e1
- Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2012;40(1):43-50
- Article: PLOS ONE. 2012;7(9):e45994
- Article: PSYCHOLOGICAL MEDICINE. 2012;42(1):111-123
- Article: MOLECULAR PSYCHIATRY. 2011;16(12):1203-1212
- Article: SCHIZOPHRENIA RESEARCH. 2011;133(1-3):120-124
- Article: ACTA PSYCHIATRICA SCANDINAVICA. 2011;124(6):447-453
- Article: MOLECULAR PSYCHIATRY. 2011;16(11):1117-1129
- Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 2011;199(5):373-379
- Article: NATURE GENETICS. 2011;43(10):969-976
- Article: NATURE GENETICS. 2011;43(10):977-983
- Article: JOURNAL OF TRAUMATIC STRESS. 2011;24(4):456-464
- Article: JOURNAL OF TRAUMATIC STRESS. 2011;24(2):183-190
- Article: MOLECULAR PSYCHIATRY. 2011;16(4):429-441
- Article: JOURNAL OF NERVOUS AND MENTAL DISEASE. 2011;199(3):162-169
- Article: NORDIC JOURNAL OF PSYCHIATRY. 2011;65(1):9-15
- Article: PLOS ONE. 2011;6(8):e22547
- Article: EPIDEMIOLOGY. 2010;21(6):805-808
- Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2010;39(5):1193-1202
- Article: JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY. 2010;51(7):850-856
- Article: ARCHIVES OF GENERAL PSYCHIATRY. 2010;67(5):529-538
- Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 2010;196(2):109-115
- Article: HUMAN HEREDITY. 2010;70(2):141-149
- Article: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. 2010;24(1):79-87
- Article: CHILD DEVELOPMENT. 2010;81(1):80-100
- Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2009;63(12):1016-1021
- Article: JOURNAL OF TRAUMATIC STRESS. 2009;22(6):497-504
- Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2009;170(11):1365-1372
- Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2009;81(5-6):367-372
- Article: PEDIATRICS. 2009;124(5):e817-e825
- Article: ULTRASOUND IN OBSTETRICS AND GYNECOLOGY. 2009;34(3):297-303
- Article: NATURE. 2009;460(7256):748-752
- Article: JOURNAL OF NERVOUS AND MENTAL DISEASE. 2009;197(5):316-323
- Article: PUBLIC HEALTH ETHICS. 2009;2(1):30-36
- Article: PSYCHIATRY RESEARCH. 2009;165(3):215-223
- Article: PLOS MEDICINE. 2009;6(2):e1000013-201
- Article: THE LANCET. 2009;373(9659):234-239
- Article: BIOSTATISTICS. 2009;10(1):70-79
- Article: BRAIN. 2008;131(Pt 10):2729-2733
- Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 2008;193(4):311-315
- Article: NATURE. 2008;455(7210):237-241
- Article: ARCHIVES OF GENERAL PSYCHIATRY. 2008;65(9):1034-1040
- Article: PSYCHOLOGICAL MEDICINE. 2008;38(8):1133-1140
- Article: PEDIATRICS. 2008;121(5):e1357-e1362
- Article: STATISTICS IN MEDICINE. 2008;27(7):1086-1105
- Article: SCANDINAVIAN JOURNAL OF PSYCHOLOGY. 2008;49(1):77-82
- Article: EPIDEMIOLOGY. 2007;18(5):577-582
- Article: BIPOLAR DISORDERS. 2007;9(3):305-309
- Article: JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY. 2007;46(3):370-377
- Article: SCHIZOPHRENIA RESEARCH. 2007;91(1-3):238-245
- Article: ARCHIVES OF GENERAL PSYCHIATRY. 2007;64(1):42-48
- Article: PSYCHOLOGICAL MEDICINE. 2006;36(10):1417-1425
- Article: EPIDEMIOLOGY. 2006;17(5):524-530
- Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2006;74(5):339-346
- Article: TWIN RESEARCH AND HUMAN GENETICS. 2005;8(4):402-408
- Article: SCHIZOPHRENIA BULLETIN. 2004;30(2):445-458
- Article: ACTA PSYCHIATRICA SCANDINAVICA. 2003;108(5):381-386
- Article: SCHIZOPHRENIA RESEARCH. 2002;58(2-3):221-229
- Article: EPIDEMIOLOGY. 2002;13(4):417-423
- Article: ARCHIVES OF GENERAL PSYCHIATRY. 1999;56(7):634-638
- Article: THE BMJ. 1999;318(7181):421-426
- Article: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 1998;16(3-4):307-316
- Article: JOURNAL OF ABNORMAL PSYCHOLOGY. 1998;107(2):228-237
- Article: SCANDINAVIAN JOURNAL OF PSYCHOLOGY. 1997;38(1):3-13
- Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 1997;170:128-133
- Article: JOURNAL OF ABNORMAL PSYCHOLOGY. 1996;105(4):626-636
- Visa fler
Alla övriga publikationer
- Letter: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2017;318(12):1182-1184
- Letter: THE LANCET PSYCHIATRY. 2015;2(11):962-963
- Published conference paper: AMERICAN JOURNAL OF PSYCHIATRY. 2014;171(11):1191-1198
- Letter: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2013;310(19):2101
- Editorial comment: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2009;170(11):1386-1387
- Meeting abstract: EARLY HUMAN DEVELOPMENT. 2007;83:S36-S37
- Meeting abstract: SCHIZOPHRENIA RESEARCH. 2006;81:3
- Editorial comment: THE LANCET. 2004;364(9433):485-487
- Meeting abstract: SCHIZOPHRENIA RESEARCH. 2003;60(1):251-252
- Meeting abstract: SCHIZOPHRENIA RESEARCH. 2003;60(1):184
- Meeting abstract: SCHIZOPHRENIA RESEARCH. 2000;41(1):68-69
- Letter: THE BMJ. 1999;318(7198):1623
- Meeting abstract: SCHIZOPHRENIA RESEARCH. 1998;29(1-2):15
Anställningar
- Professor Emeritus/Emerita, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2023-2024
Examina och utbildning
- Docent, Docent i medicinsk psykologi, Uppsala Universitet, 2002
Handledare
- Emma Nilsson, Genetic epidemiological studies of adverse pregnancy outcome and the role of schizophrenia