Charlotte Thålin

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

My interest in the immune system developed during my Ph.D. studies when investigating the role of neutrophils and neutrophil extracellular traps (NETs) in cancer biology. My research team at the Department of Clinical Sciences, Danderyd Hospital, now includes five Ph.D. students focusing on NETs in cancer and cancer associated thrombosis and, recently, on immune responses following COVID-19 infection and vaccination.
We initiated the MEDECA study 2017, investigating immune markers as diagnostic tools in identifying patients with occult cancer. Faced with the COVID-19 pandemic, we expanded our clinical studies to also investigate longitudinal humoral and cellular immune responses following SARS-CoV-2 infection and vaccination in the COMMUNITY study. As a physician at the department of medicine, Danderyd Hospital, I divide my time between clinical work and research.
https://ki.se/en/kids/community

Utvalda publikationer

Letter: THE LANCET REGIONAL HEALTH. EUROPE. 2024;38:100872
Prevalence of SARS-CoV-2 infections among Swedish healthcare workers on duty in December 2023
Aguilera K; Bladh O; Marking U; Norin NG; Rihani A; Ujvari D; Ning FC; Klingstroem J; Havervall S; Aberg M; Blom K; Alm JJ; Thalin C
Letter: THE LANCET INFECTIOUS DISEASES. 2024;24(2):e80-e81
Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster in Sweden
Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1346749
Comparison of SARS-CoV-2 spike-specific IgA and IgG in nasal secretions, saliva and serum
Bladh O; Aguilera K; Marking U; Kihlgren M; Norin NG; Smed-Sorensen A; Chen MS; Klingstrom J; Blom K; Russell MW; Havervall S; Thalin C; Aberg M
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2023;389(17):1626-1628
Mucosal and Serum Antibodies 3 Weeks after Symptomatic BA.2.86 Infection
Bladh O; Greilert-Norin N; Havervall S; Marking U; Aguilera K; Alm JJ; Blom K; Aberg M; Klingstrom J; Thalin C
Letter: THE LANCET REGIONAL HEALTH. EUROPE. 2023;33:100725
Point prevalence of SARS-CoV-2 infection among healthcare workers in March and June 2023 in Sweden
Blom K; Bladh O; Havervall S; Marking U; Norin NG; Alm JJ; Klingstrom J; Thalin C
Letter: THE LANCET INFECTIOUS DISEASES. 2023;23(8):e272-e273
Mucosal IgA protects against BQ.1 and BQ.1.1 infection
Marking U; Bladh O; Havervall S; Greilert-Norin N; Gordon M; Alm JJ; Blom K; Aberg M; Klingstrom J; Thalin C
Letter: THE LANCET MICROBE. 2023;4(7):e488
Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose
Bladh O; Marking U; Havervall S; Norin NG; Aguilera K; Hober S; Smed-Soerensen A; Gordon M; Blom K; Aberg M; Klingstrom J; Thalin C
Article: NATURE COMMUNICATIONS. 2023;14(1):1577
Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers
Marking U; Havervall S; Norin NG; Bladh O; Christ W; Gordon M; Ng H; Blom K; Phillipson M; Mangsbo S; Alm JJ; Smed-Sorensen A; Nilsson P; Hober S; Aberg M; Klingstroem J; Thalin C
Letter: THE LANCET INFECTIOUS DISEASES. 2023;23(2):150-152
7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection
Marking U; Bladh O; Havervall S; Svensson J; Greilert-Norin N; Aguilera K; Kihlgren M; Salomonsson A-C; Mansson M; Gallini R; Kriegholm C; Bacchus P; Hober S; Gordon M; Blom K; Smed-Sorensen A; Aberg M; Klingstrom J; Thalin C
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2022;387(14):1333-1336
Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection
Havervall S; Marking U; Svensson J; Greilert-Norin N; Bacchus P; Nilsson P; Hober S; Gordon M; Blom K; Klingstrom J; Aberg M; Smed-Sorensen A; Thalin C
Letter: EMERGING INFECTIOUS DISEASES. 2022;28(10):2119-2121
Infection Rate of SARS-CoV-2 in Asymptomatic Healthcare Workers, Sweden, June 2022
Blom K; Havervall S; Marking U; Norin NG; Bacchus P; Groenheit R; Brave A; Thalin C; Klingstrom J
Letter: THE LANCET INFECTIOUS DISEASES. 2022;22(7):943-945
Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
Blom K; Marking U; Havervall S; Norin NG; Gordon M; Garcia M; Tecleab T; Christ W; Forsell M; Phillipson M; Nilsson P; Mangsbo S; Hober S; Aberg M; Klingstrom J; Thalin C
Article: VACCINES. 2022;10(3):359
Duration of SARS-CoV-2 Immune Responses Up to Six Months Following Homologous or Heterologous Primary Immunization with ChAdOx1 nCoV-19 and BNT162b2 mRNA Vaccines
Marking U; Havervall S; Greilert-Norin N; Ng H; Blom K; Nilsson P; Phillipson M; Hober S; Nilsson C; Mangsbo S; Christ W; Klingstrom J; Gordon M; Aberg M; Thalin C
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2022;11(4):e1388
Impact of SARS-CoV-2 infection on vaccine-induced immune responses over time
Havervall S; Marking U; Greilert-Norin N; Gordon M; Ng H; Christ W; Phillipson M; Nilsson P; Hober S; Blom K; Klingstrom J; Mangsbo S; Aberg M; Thalin C
Article: JOURNAL OF INTERNAL MEDICINE. 2022;291(1):72-80
Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19
Havervall S; Ng H; Jernbom Falk A; Greilert-Norin N; Manberg A; Marking U; Lauren I; Gabrielsson L; Salomonsson A-C; Aguilera K; Kihlgren M; Mansson M; Rosell A; Hellstrom C; Andersson E; Olofsson J; Skoglund L; Yousef J; Pin E; Lord M; Aberg M; Hedhammar M; Tegel H; Donnes P; Phillipson M; Nilsson P; Klingstrom J; Mangsbo S; Hober S; Thalin C
Article: EBIOMEDICINE. 2021;70:103523
Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2
Havervall S; Marking U; Greilert-Norin N; Ng H; Gordon M; Salomonsson A-C; Hellstrom C; Pin E; Blom K; Mangsbo S; Phillipson M; Klingstrom J; Hober S; Nilsson P; Aberg M; Thalin C
Letter: THE LANCET HAEMATOLOGY. 2021;8(7):e475
Sustained prothrombotic changes in convalescent patients with COVID-19
Meijenfeldt FAV; Thalin C; Lisman T
Letter: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2021;325(19):2015-2016
Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers
Havervall S; Rosell A; Phillipson M; Mangsbo SM; Nilsson P; Hober S; Thalin C
Letter: BLOOD ADVANCES. 2021;5(3):756-759
Sustained prothrombotic changes in COVID-19 patients 4 months after hospital discharge
von Meijenfeldt FA; Havervall S; Adelmeijer J; Lundstrom A; Magnusson M; Mackman N; Thalin C; Lisman T
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(2):988-994
Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19
Ng H; Havervall S; Rosell A; Aguilera K; Parv K; von Meijenfeldt FA; Lisman T; Mackman N; Thalin C; Phillipson M
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(2):878-882
Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality-Brief Report
Rosell A; Havervall S; von Meijenfeldt F; Hisada Y; Aguilera K; Grover SP; Lisman T; Mackman N; Thalin C
Article: NATURE COMMUNICATIONS. 2020;11(1):5064
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
Rudberg A-S; Havervall S; Manberg A; Jernbom Falk A; Aguilera K; Ng H; Gabrielsson L; Salomonsson A-C; Hanke L; Murrell B; McInerney G; Olofsson J; Andersson E; Hellstrom C; Bayati S; Bergstrom S; Pin E; Sjoberg R; Tegel H; Hedhammar M; Phillipson M; Nilsson P; Hober S; Thalin C
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2020;18(10):2732-2743
Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma
Thalin C; Aguilera K; Hall NW; Marunde MR; Burg JM; Rosell A; Daleskog M; Mansson M; Hisada Y; Meiners MJ; Sun Z-W; Whelihan MF; Cheek MA; Howard SA; Saxena-Beem S; Noubouossie DF; Key NS; Sheikh SZ; Keogh M-C; Cowles MW; Lundstrom S; Mackman N; Wallen H; Johnstone AL
Review: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2019;39(9):1724-1738
Neutrophil Extracellular Traps Villains and Targets in Arterial, Venous, and Cancer-Associated Thrombosis
Thalin C; Hisada Y; Lundstrom S; Mackman N; Wallen H
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Artiklar

Journal article: NATURE COMMUNICATIONS. 2024;15(1):8941
Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19
Jernbom AF; Skoglund L; Pin E; Sjoberg R; Tegel H; Hober S; Rostami E; Rasmusson A; Cunningham JL; Havervall S; Thalin C; Manberg A; Nilsson P
Journal article: HEALTH SECURITY. 2024;22(5):394-397
Logistics for Rapid Isolation of Viruses From Humans
Bacchus P; Christ W; Frisell A; Greilert-Norin N; Marking U; Havervall S; Leopoldson F; Markstrom A-C; Potapeiko A; Gisselsson D; Thalin C; Klingstrom J; Brave A; Blom K; Groenheit R
Journal article: SCIENTIFIC REPORTS. 2024;14(1):22735
Oneyear longitudinal study on biomarkers of blood-brain barrier permeability in COVID-19 patients.
Wallensten J; Havervall S; Power Y; Åsberg M; Borg K; Nager A; Thålin C; Mobarrez F
Article: INFLAMMATION. 2024;:1-10
Plasma H3Cit-DNA Discriminates Between Cancer and Inflammation in a Cohort of Patients with Unspecific Cancer Symptoms
Wannberg F; Hjalmar V; Ng H; Johansson C; Probert F; Phillipson M; Aberg M; Gordon M; Mackman N; Rosell A; Thalin C
Article: PLOS ONE. 2024;19(7):e0306290
High prevalence of long-term olfactory disorders in healthcare workers after COVID-19: A case-control study
Frasnelli J; Tognetti A; Winter AL; Thunell E; Olsson MJ; Greilert N; Olofsson JK; Havervall S; Thalin C; Lundstrom JN
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(1):e13333
No indication of aberrant neutrophil extracellular trap release in indolent or advanced systemic mastocytosis
Rosell A; Karlstrom C; Dahlin JS; Boey D; Klimkowska M; Ax K; Thalin C; Ungerstedt J
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2023;21(11):3166-3174
Neutrophil extracellular trap formation is an independent risk factor for occult cancer in patients presenting with venous thromboembolism
Rosell A; Gautam G; Wannberg F; Ng H; Gry H; Vingback E; Lundstrom S; Mackman N; Wallen H; Westerlund E; Thalin C
Journal article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2023;7:101306
PB0707 Neutrophil Extracellular Traps Promote Cancer-Associated Inflammation and Myocardial Stress
Cedervall J; Herre M; Vemuri K; Dragomir A; Melo F; Svensson A; Thålin C; Rosell A; Hjalmar V; Wallén H; Lindman H; Pejler G; Hagström E; Hultström M; Larsson A; Olsson A
Journal article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2023;7:100824
PB1070 Small and Large Extracellular Vesicles have Different Tissue Factor Activity in Cancer, Sepsis, and COVID-19
Sachetto A; Archibald S; Hisada Y; Rosell A; Havervall S; van Es N; Nieuwland R; Campbell R; Middleton E; Rondina M; Thålin C; Mackman N
Article: THE LANCET REGIONAL HEALTH. EUROPE. 2023;30:100646
Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study.
Vikström L; Fjällström P; Gwon Y-D; Sheward DJ; Wigren-Byström J; Evander M; Bladh O; Widerström M; Molnar C; Rasmussen G; Bennet L; Åberg M; Björk J; Tevell S; Thålin C; Blom K; Klingström J; Murrell B; Ahlm C; Normark J; Johansson AF; Forsell MNE
Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2023;7(3):100124
Tissue factor activity of small and large extracellular vesicles in different diseases
Sachetto ATA; Archibald SJ; Hisada Y; Rosell A; Havervall S; van Es N; Nieuwland R; Campbell RA; Middleton EA; Rondina MT; Thalin C; Mackman N
Article: ONCOIMMUNOLOGY. 2022;11(1):2049487
Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress
Cedervall J; Herre M; Dragomir A; Rabelo-Melo F; Svensson A; Thalin C; Rosell A; Hjalmar V; Wallen H; Lindman H; Pejler G; Hagstrom E; Hultstrom M; Larsson A; Olsson AK
Article: CYTOKINE. 2022;159:156020
IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in Sweden
Ziegler L; Lundstrom A; Havervall S; Thalin C; Gigante B
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(5):e13215
Impact of monocyte-related modulators and kidney function on mortality in hospitalized patients with COVID-19
Sendic S; Mansouri L; Havervall S; Thalin C; Lundahl J; Jacobson SH
Article: BMC NEPHROLOGY. 2022;23(1):299
"Role of kidney function and concentrations of BAFF, sPD-L1 and sCD25 on mortality in hospitalized patients with COVID-19"
Mansouri L; Sendic S; Havervall S; Thalin C; Jacobson SH; Lundahl J
Article: EMBO MOLECULAR MEDICINE. 2022;14(8):e15230
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants
Monteil V; Eaton B; Postnikova E; Murphy M; Braunsfeld B; Crozier I; Kricek F; Niederhofer J; Schwarzbock A; Breid H; Devignot S; Klingstrom J; Thalin C; Kellner MJ; Christ W; Havervall S; Mereiter S; Knapp S; Jimenez AS; Bugajska-Schretter A; Dohnal A; Ruf C; Gugenberger R; Hagelkruys A; Montserrat N; Kozieradzki I; Ali OH; Stadlmann J; Holbrook MR; Schmaljohn C; Oostenbrink C; Shoemaker RH; Mirazimi A; Wirnsberger G; Penninger JM
Journal article: THROMBOSIS RESEARCH. 2022;213:s2-s3
OC-04: Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress
Cedervall J; Herre M; Dragomir A; Rabelo-Melo F; Svensson A; Thâlin C; Rosell A; Hjalmar V; Wallén H; Lindman H; Pejler G; Hagstrom E; Hultstrom M; Larsson A; Olsson AK
Article: IMMUNITY, INFLAMMATION AND DISEASE. 2022;10(4):e595
Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology
Lauren I; Havervall S; Ng H; Lord M; Pettke A; Greilert-Norin N; Gabrielsson L; Chourlia A; Amoedo-Leite C; Josyula VS; Eltahir M; Kerzeli I; Falk AJ; Hober J; Christ W; Wiberg A; Hedhammar M; Tegel H; Burman J; Xu F; Pin E; Manberg A; Klingstrom J; Christoffersson G; Hober S; Nilsson P; Philipson M; Donnes P; Lindsay R; Thalin C; Mangsbo S
Article: ANTICANCER RESEARCH. 2022;42(2):965-971
Circulating Markers of Neutrophil Extracellular Traps (NETs) in Patients With Ovarian Tumors
Dobilas A; Thalin C; Wallen H; Borgfeldt C
Article: NEW BIOTECHNOLOGY. 2022;66:46-52
A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies
Mravinacova S; Jonsson M; Christ W; Klingstrom J; Yousef J; Hellstrom C; Hedhammar M; Havervall S; Thalin C; Pin E; Tegel H; Nilsson P; Manberg A; Hober S
Article: PLOS ONE. 2022;17(7):e0270865
Markers of neutrophil activation and neutrophil extracellular traps in diagnosing patients with acute venous thromboembolism: A feasibility study based on two VTE cohorts
Smith P; Rosell A; Farm M; Bruzelius M; Gatica KA; Mackman N; Odeberg J; Thalin C
Article: PLOS ONE. 2022;17(1):e0262169
SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection
Havervall S; Falk AJ; Klingstrom J; Ng H; Greilert-Norin N; Gabrielsson L; Salomonsson A-C; Isaksson E; Rudberg A-S; Hellstrom C; Andersson E; Olofsson J; Skoglund L; Yousef J; Pin E; Christ W; Olausson M; Hedhammar M; Tegel H; Mangsbo S; Phillipson M; Manberg A; Hober S; Nilsson P; Thalin C
Article: SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2021;47(07):775-786
Fibrin Network Porosity and Endo-/Exogenous Thrombin Cross-talk
He S; Wallen H; Thalin C; Svensson J; Blomback M
Article: JOURNAL OF MEDICAL VIROLOGY. 2021;93(10):5908-5916
Soluble angiotensin-converting enzyme 2 is transiently elevated in COVID-19 and correlates with specific inflammatory and endothelial markers
Lundstrom A; Ziegler L; Havervall S; Rudberg A-S; von Meijenfeldt F; Lisman T; Mackman N; Sanden P; Thalin C
Article: SCIENTIFIC REPORTS. 2021;11(1):18025
Neutrophil extracellular traps in patients with liver cirrhosis and hepatocellular carcinoma
Zenlander R; Havervall S; Magnusson M; Engstrand J; Agren A; Thalin C; Stal P
Article: SCIENTIFIC REPORTS. 2021;11(1):14015
An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism
Razzaq M; Iglesias MJ; Ibrahim-Kosta M; Goumidi L; Soukarieh O; Proust C; Roux M; Suchon P; Boland A; Daiain D; Olaso R; Havervall S; Thalin C; Butler L; Deleuze J-F; Odeberg J; Morange P-E; Tregouet D-A
Article: NATURE COMMUNICATIONS. 2021;12(1):3695
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2
Roxhed N; Bendes A; Dale M; Mattsson C; Hanke L; Dodig-Crnkovic T; Christian M; Meineke B; Elsasser S; Andrell J; Havervall S; Thalin C; Eklund C; Dillner J; Beck O; Thomas CE; McInerney G; Hong M-G; Murrell B; Fredolini C; Schwenk JM
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(Supplement_1):gfab092.0010
MO132IMPACT OF MONOCYTE CHEMOATTRACTANTS ON IN-HOSPITAL MORTALITY IN RELATION TO KIDNEY FUNCTION IN PATIENTS WITH COVID-19
Sendic S; Mansouri L; Havervall S; Thålin C; Lundahl J; Jacobson SH
Article: CIRCULATION RESEARCH. 2021;128(11):1694-1707
Perivascular Macrophages Regulate Blood Flow Following Tissue Damage
Vagesjo E; Parv K; Ahl D; Seignez C; Herrera Hidalgo C; Giraud A; Leite C; Korsgren O; Wallen H; Juusola G; Hakovirta HH; Rundqvist H; Essand M; Holm L; Johnson RS; Thalin C; Korpisalo P; Christoffersson G; Phillipson M
Article: THROMBOSIS AND HAEMOSTASIS. 2021;121(05):584-593
High Thrombin Generation after Acute Ischemic Stroke or Transient Ischemic Attack Is Associated with a Reduced Risk of Recurrence: An Observational Cohort Study
Lundstrom A; Anggardh-Rooth E; Mobarrez F; Thalin C; Gigante B; Laska AC; Wallen H
Journal article: THROMBOSIS RESEARCH. 2021;200:s78
PO-107 Tumor-induced neutrophil extracellular traps contribute to organ failure in individuals with cancer
Cedervall J; Herre M; Thålin C; Wallén H; Hjalmar V; Hagström E; Larsson A; Olsson AK
Journal article: THROMBOSIS RESEARCH. 2021;200:s32
PO-28 Circulating markers of neutrophil activation and nets, but not of coagulation and fibrinolysis, predict mortality in patients with terminal cancer
Rosell A; Aguilera K; Daleskog M; Hisada Y; Mackman N; Lundström S; Wallén H; Thålin C
Journal article: THROMBOSIS RESEARCH. 2021;200:s79-s80
PO-110 Identification of novel biomarkers to aid in the detection of occult cancer in high-risk patient populations: the BIT and MEDECA studies
Thålin C; Rosell A; Gabrielsson L; Månsson M; Aguilera K; Lundström S; Söderberg M; Hjalmar V; Wallén H; Group FTBAMS
Article: SCIENTIFIC REPORTS. 2021;11(1):5074
Prognostic value of circulating markers of neutrophil activation, neutrophil extracellular traps, coagulation and fibrinolysis in patients with terminal cancer
Rosell A; Aguilera K; Hisada Y; Schmedes C; Mackman N; Wallen H; Lundstrom S; Thalin C
Article: PLOS ONE. 2021;16(9):e0258041
An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses
Mangsbo SM; Havervall S; Lauren I; Lindsay R; Falk AJ; Marking U; Lord M; Buggert M; Donnes P; Christoffersson G; Nilsson P; Hober S; Phillipson M; Klingstrom J; Thalin C
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2021;11:795026
A Model Predicting Mortality of Hospitalized Covid-19 Patients Four Days After Admission: Development, Internal and Temporal-External Validation
Heber S; Pereyra D; Schrottmaier WC; Kammerer K; Santol J; Rumpf B; Pawelka E; Hanna M; Scholz A; Liu M; Hell A; Heiplik K; Lickefett B; Havervall S; Traugott MT; Neuboeck MJ; Schoergenhofer C; Seitz T; Firbas C; Karolyi M; Weiss G; Jilma B; Thalin C; Bellmann-Weiler R; Salzer HJF; Szepannek G; Fischer MJM; Zoufaly A; Gleiss A; Assinger A
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1312
Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay
Hober S; Hellstrom C; Olofsson J; Andersson E; Bergstrom S; Jernbom Falk A; Bayati S; Mravinacova S; Sjoberg R; Yousef J; Skoglund L; Kanje S; Berling A; Svensson A-S; Jensen G; Enstedt H; Afshari D; Xu LL; Zwahlen M; von Feilitzen K; Hanke L; Murrell B; McInerney G; Karlsson Hedestam GB; Lendel C; Roth RG; Skoog I; Svenungsson E; Olsson T; Fogdell-Hahn A; Lindroth Y; Lundgren M; Maleki KT; Lagerqvist N; Klingstrom J; Da Silva Rodrigues R; Muschiol S; Bogdanovic G; Arroyo Muhr LS; Eklund C; Lagheden C; Dillner J; Sivertsson A; Havervall S; Thalin C; Tegel H; Pin E; Manberg A; Hedhammar M; Nilsson P
Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2021;5(1):132-141
Prothrombotic changes in patients with COVID-19 are associated with disease severity and mortality
von Meijenfeldt FA; Havervall S; Adelmeijer J; Lundstrom A; Rudberg A-S; Magnusson M; Mackman N; Thalin C; Lisman T
Article: TRANSLATIONAL STROKE RESEARCH. 2020;11(4):708-719
Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
Lundstrom A; Mobarrez F; Rooth E; Thalin C; von Arbin M; Henriksson P; Gigante B; Laska A-C; Wallen H
Article: HAEMATOLOGICA. 2020;105(1):218-225
Neutrophils and neutrophil extracellular traps enhance venous thrombosis in mice bearing human pancreatic tumors
Hisada Y; Grover SP; Maqsood A; Houston R; Ay C; Noubouossie DF; Cooley BC; Wallen H; Key NS; Thalin C; Farkas AZ; Farkas VJ; Tenekedjiev K; Kolev K; Mackman N
Article: JOURNAL OF THROMBOSIS AND THROMBOLYSIS. 2019;48(1):111-118
A clinical practice-based evaluation of the RIETE score in predicting occult cancer in patients with venous thromboembolism
Rosell A; Lundstrom S; Mackman N; Wallen H; Thalin C
Article: SCIENTIFIC REPORTS. 2018;8(1):12641
Circulating H3Cit is elevated in a human model of endotoxemia and can be detected bound to microvesicles
Goranson SP; Thalin C; Lundstrom A; Hallstrom L; Lasselin J; Wallen H; Soop A; Mobarrez F
Article: THROMBOSIS RESEARCH. 2018;165:1-5
Comparison of microvesicle tissue factor activity in non-cancer severely ill patients and cancer patients
Hisada Y; Thalin C; Lundstrom S; Wallen H; Mackman N
Article: PLOS ONE. 2018;13(1):e0191231
Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer
Thalin C; Lundstrom S; Seignez C; Daleskog M; Lundstrom A; Henriksson P; Helleday T; Phillipson M; Wallen H; Demers M
Article: IMMUNOLOGIC RESEARCH. 2017;65(3):706-712
Validation of an enzyme-linked immunosorbent assay for the quantification of citrullinated histone H3 as a marker for neutrophil extracellular traps in human plasma
Thalin C; Daleskog M; Goransson SP; Schatzberg D; Lasselin J; Laska A-C; Kallner A; Helleday T; Wallen H; Demers M
Article: THROMBOSIS RESEARCH. 2016;139:56-64
NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation
Thalin C; Demers M; Blomgren B; Wong SL; von Arbin M; von Heijne A; Laska AC; Wallen H; Wagner DD; Aspberg S
Article: JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS. 2014;2(2):2324709614539283
Trousseau's Syndrome, a Previously Unrecognized Condition in Acute Ischemic Stroke Associated With Myocardial Injury.
Thalin C; Blomgren B; Mobarrez F; Lundstrom A; Laska AC; von Arbin M; von Heijne A; Rooth E; Wallen H; Aspberg S
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Alla övriga publikationer

Letter: THROMBOSIS RESEARCH. 2024;235:18-21
Analysis of NETs (neutrophil extracellular traps) in coronary thrombus and peripheral blood of patients with ST-segment elevation myocardial infarction
Blasco A; Rosell A; Castejon R; Coronadof MJ; Royuela A; Ramil E; Elorza S; Thalin C; Martin P; Angulo B; Rascon B; Garcia-Gomez S; Zabala I; Ortega J; Silva L; Bellas C
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2022;387(21):e55
Mucosal IgA against SARS-CoV-2 Omicron Infection. Reply.
Åberg M; Smed-Sörensen A; Thålin C
Published conference paper: THROMBOSIS RESEARCH. 2022;213:S35-S41
Neutrophil extracellular traps and cancer-associated thrombosis
Rosell A; Martinod K; Mackman N; Thalin C
Letter: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2022;20(1):267-269
Persistent endotheliopathy in the pathogenesis of long COVID syndrome: Comment from von Meijenfeldt et al.
von Meijenfeldt FA; Havervall S; Adelmeijer J; Thalin C; Lisman T
Conference publication: THROMBOSIS RESEARCH. 2022;213:S2-S3
Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress
Cedervall J; Herre M; Dragomir A; Rabelo-Melo F; Svensson A; Thalin C; Rosell A; Hjalmar V; Wallen H; Lindman H; Pejler G; Hagstrom E; Hultstrom M; Larsson A; Olsson AK
Letter: THROMBOSIS AND HAEMOSTASIS. 2021;121(12):1668-1669
COVID-19 is Associated with an Acquired Factor XIII Deficiency
von Meijenfeldt FA; Havervall S; Adelmeijer J; Lundstrom A; Magnusson M; Mackman N; Thalin C; Lisman T
Letter: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(6):e381-e382
Response by Mackman et al to Letter Regarding Article, "Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality-Brief Report"
Mackman N; Hisada Y; Grover SP; Rosell A; Havervall S; von Meijenfeldt F; Aguilera K; Lisman T; Thalin C
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(4):E98-E100
Elevated factor V activity and antigen levels in patients with Covid-19 are related to disease severity and 30-day mortality
von Meijenfeldt FA; Havervall S; Adelmeijer J; Lundstrom A; Magnusson M; Mackman N; Thalin C; Lisman T
Review: SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2021;47(01):63-73
The Clotting Trigger Is an Important Determinant for the Coagulation Pathway In Vivo or In Vitro-Inference from Data Review
He S; Cao H; Thalin C; Svensson J; Blomback M; Wallen H
Conference publication: THROMBOSIS RESEARCH. 2021;200:S78
Tumor-induced neutrophil extracellular traps contribute to organ failure in individuals with cancer
Cedervall J; Herre M; Thalin C; Wallen H; Hjalmar V; Hagstrom E; Larsson A; Olsson AK
Conference publication: THROMBOSIS RESEARCH. 2021;200:S79-S80
Identification of novel biomarkers to aid in the detection of occult cancer in high-risk patient populations: the BIT and MEDECA studies
Thalin C; Rosell A; Gabrielsson L; Mansson M; Aguilera K; Lundstrom S; Soderberg M; Hjalmar V; Wallen H
Conference publication: THROMBOSIS RESEARCH. 2021;200:S32
Circulating markers of neutrophil activation and nets, but not of coagulation and fibrinolysis, predict mortality in patients with terminal cancer
Rosell A; Aguilera K; Daleskog M; Hisada Y; Mackman N; Lundstrom S; Wallen H; Thalin C
Conference publication: THROMBOSIS RESEARCH. 2021;200:S77
Quantification of citrullinated histones in human blood samples: challenges and development of a nucleosome-based assay to quantify H3Cit-DNA in human plasma
Thalin C; Aguilera K; Hall NW; Marunde MR; Burg JM; Rosell A; Daleskog M; Hisada Y; Meiners MJ; Sun ZW; Whelihan MF; Cheek MA; Howard SA; Saxena-Beem S; Noubouossie DF; Key NS; Sheikh SZ; Keogh MC; Cowles MW; Lundstrom S; Mackman N; Wallen H; Johnstone AL
Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36:151-U993
IMPACT OF MONOCYTE CHEMOATTRACTANTS ON IN-HOSPITAL MORTALITY IN RELATION TO KIDNEY FUNCTION IN PATIENTS WITH COVID-19
Sendic S; Mansouri L; Havervall S; Thalin C; Lundahl J; Jacobson SH
Conference publication: JOURNAL OF HEPATOLOGY. 2021;75:S339
Markers of neutrophil extracellular traps are elevated in patients with Child-Pugh B and C liver cirrhosis or large hepatocellular carcinomas
Zenlander R; Havervall S; Magnusson M; Agren A; Thalin C; Stal P
Review: LAKARTIDNINGEN. 2019;116:FI3S
[The neutrophil's multifaceted traps - the Dr Jekyll and Mr Hyde of the immune system].
Thålin C; Rosell A; Lundström S; Wallén H
Meeting abstract: THROMBOSIS RESEARCH. 2018;164:S233-S234
Performance of the RIETE score in an unselected VTE cohort
Rosell A; Lundstrom S; Wallen H; Thalin C
Thesis / dissertation: 2017
Troponin elevation in acute stroke : clinical characteristics and the link to cancer-associated neutrophil extracellular traps
Thålin, Charlotte
Review: JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES. 2015;24(10):2390-2396
Elevated Troponin Levels in Acute Stroke Patients Predict Long-term Mortality
Thalin C; Rudberg A-S; Johansson F; Jonsson F; Laska AC; Nygren AT; von Arbin M; Wallen H; Aspberg S
Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2015;10:285-286
Elevated troponin levels in acute stroke patients predict long-term mortality
Thalin C; Rudberg AS; Laska AC; von Arbin M; Wallen H; Aspberg S
Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13:814
Cancer inducing netosis promotes widespread arterial thrombosis presenting as ischemic stroke with troponin elevation
Thalin C; Demers M; Blomgren B; Laska AC; von Arbin M; Wallen H; Wagner D; Aspberg S
Conference publication: CEREBROVASCULAR DISEASES. 2014;37:230
Cancer associated generalized thrombosis contributing to elevated levels of plasma troponinin A patients with acute ischemic stroke
Thalin C; Lundstrom A; Blomgren B; Mobarrez F; Laska AC; von Arbin M; Wallen H; Aspberg S
Conference publication: EUROPEAN HEART JOURNAL. 2014;35:992
Cancer associated microthrombosis; a contributing factor to troponin elevation in acute ischemic stroke
Thalin C; Blomgren B; Lundstrom A; Mobarrez F; Laska AC; Von Arbin M; Wallen H; Aspberg S
Preprint: BIORXIV.
Neutralisation sensitivity of the SARS-CoV-2 BA.2.87.1 variant
Sheward DJ; Marking U; Bladh O; Held S; Looyens E; Vandenabeele L; Muschiol S; Aguilera K; Norin NG; Öling S; Westerberg M; Martin D; Hedestam GBK; Albert J; Thålin C; Murrell B
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Forskningsbidrag

Towards unified quantitative assays of mucosal immunity
National Institutes of Health
1 September 2023 - 1 September 2024
Nya biomarkörer vid detektion av dold cancer i högrisk populationer
Vetenskapsrådet
1 January 2023 - 31 December 2025
Novel biomarkers in screening for occult cancer in high-risk patient populations
The Swedish Research Council
1 January 2023 - 31 December 2025
The COMMUNITY study - Covid-19 Immunity
Knut och Alice Wallenbergs Stiftelse
31 March 2021 - 31 March 2023
Long-term sequele after mild SARS-CoV-2 infection
Swedish Heart-Lung Foundation
1 January 2021 - 31 December 2021
COMMUNITY: Covid-19 Immunity
Family Lundblad Foundation
1 January 2021 - 31 December 2023
COMMUNITY: Covid-19 Immunity
Jonas and Christina af Jochnick Foundation
1 August 2020 - 31 August 2025
COMMUNITY: Covid-19 Immunity
Region Stockholm
1 August 2020 - 31 August 2023
MEDECA: Markers in Early Cancer Detection
Stitching af Jochnick Foundation
1 August 2018 - 1 August 2025

Anställningar

Anknuten till Forskning, Kliniska vetenskaper, Danderyds sjukhus, Karolinska Institutet, 2023-2026

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Docent, immunologi, Karolinska Institutet, 2022
Medicine Doktorsexamen, Institutionen för kliniska vetenskaper, Danderyds sjukhus, Karolinska Institutet, 2017
Läkarexamen, Karolinska Institutet, 2010

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