Bianka Karshikoff

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Jag forskar inom området Psykoneuroimmunologi, som handlar om hur
immunsystemet påverkar hjärnan och beteendet. Under min doktorsavhandling
använde jag experimentella inflammationsmodeller för att förstå hur
inflammation påverkar upplevelsen av smärta, och hur hjärnan påverkas av
inflammation. I min nuvarande forskning har jag ett translationellt
perspektiv, där teorier från experimentell forskning testas i klinisk
miljö. Några av de frågeställningar jag har är om pågående, låggradig
inflammation påverkar kognitiv beteendeterapi för kronisk smärta, och om
den inflammatoriska belastningen under pollensäsong påverkar smärtsystemet
hos allergiska patienter.

Artiklar

Article: PHYSIOLOGY & BEHAVIOR. 2023;271:114358
Links between brain neuroimaging and blood inflammatory markers in urological chronic pelvic pain syndrome
Martucci KT; Karshikoff B; Mackey SC
Article: SCIENTIFIC REPORTS. 2023;13(1):16709
Human scent as a first-line defense against disease
Gordon AR; Lundstrom JN; Kimball BA; Karshikoff B; Sorjonen K; Axelsson J; Lekander M; Olsson MJ
Article: BIOMEDICINES. 2023;11(3):713
Inflammatory Blood Signature Related to Common Psychological Comorbidity in Chronic Pain
Karshikoff B; Wahlen K; Astrom J; Lekander M; Holmstrom L; Wicksell RKK
Article: NEUROIMMUNOMODULATION. 2023;30(1):338-345
Olfactory cues of naturally occurring systemic inflammation: A pilot study of seasonal allergy
Tognetti A; Saluja S; Lybert N; Lasselin J; Tamm S; Lensmar C; Karshikoff B; Cervenka S; Lekander M; Olsson MJ
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2022;106:47
Anxiety and depression following pollen exposure in severe seasonal allergy
Anckers F; Lensmar C; Karshikoff B; Tammb S; Andreasson A; Lekander M
Article: JOURNAL OF CLINICAL MEDICINE. 2022;11(9):2285
Baseline Pro-Inflammatory Cytokine Levels Moderate Psychological Inflexibility in Behavioral Treatment for Chronic Pain
Karshikoff B; Astrom J; Holmstrom L; Lekander M; Kemani MK; Wicksell RK
Article: SCANDINAVIAN JOURNAL OF PAIN. 2022;22(1):88-96
Evaluating the construct validity and internal consistency of the Sickness Questionnaire in a Swedish sample of adults with longstanding pain
Astrom J; Holmstrom L; Karshikoff B; Andreasson A; Kemani MK
Article: BRAIN BEHAVIOR AND IMMUNITY. 2022;99:9-16
Anterior insula morphology and vulnerability to psychopathology-related symptoms in response to acute inflammation
Mansson KNT; Lasselin J; Karshikoff B; Axelsson J; Engler H; Schedlowski M; Benson S; Petrovic P; Lekander M
Article: FRONTIERS IN PSYCHIATRY. 2021;12:651083
Relationship Between Blood Cytokine Levels, Psychological Comorbidity, and Widespreadness of Pain in Chronic Pelvic Pain
Karshikoff B; Martucci KT; Mackey S
Article: NATURE AND SCIENCE OF SLEEP. 2021;13:775-789
Objective and Subjective Sleep in Rheumatoid Arthritis and Severe Seasonal Allergy: Preliminary Assessments of the Role of Sickness, Central and Peripheral Inflammation
Tamm S; Lensmar C; Andreasson A; Axelsson J; Moren AF; Grunewald J; Gyllfors P; Karshikoff B; Kosek E; Lampa J; Hoglund CO; Strand V; Cervenka S; Lekander M
Article: BRAIN, BEHAVIOR, & IMMUNITY - HEALTH. 2020;2:100028
Patients with ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) and chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin at peak inflammation
Jonsjo MA; Astrom J; Jones MP; Karshikoff B; Lodin K; Holmstrom L; Agreus L; Wicksell RK; Axelsson J; Lekander M; Olsson GL; Kemani M; Andreasson A
Article: BRAIN BEHAVIOR AND IMMUNITY. 2020;83:309-314
Fatigue and sleepiness responses to experimental inflammation and exploratory analysis of the effect of baseline inflammation in healthy humans
Lasselin J; Karshikoff B; Axelsson J; Akerstedt T; Benson S; Engler H; Schedlowski M; Jones M; Lekander M; Andreasson A
Article: PLOS ONE. 2019;14(3):e0212313
The effect of a transient immune activation on subjective health perception in two placebo controlled randomised experiments
Andreasson A; Karshikoff B; Lidberg L; Akerstedt T; Ingvar M; Hoglund CO; Axelsson J; Lekander M
Article: CHEMICAL SENSES. 2018;43(9):711-719
Detection of Inflammation via Volatile Cues in Human Urine
Gordon AR; Kimball BA; Sorjonen K; Karshikoff B; Axelsson J; Lekander M; Lundstrom JN; Olsson MJ
Article: JOURNAL OF HEALTH PSYCHOLOGY. 2018;23(11):1452-1463
A global measure of sickness behaviour: Development of the Sickness Questionnaire
Andreasson A; Wicksell RK; Lodin K; Karshikoff B; Axelsson J; Lekander M
Article: BRAIN BEHAVIOR AND IMMUNITY. 2018;68:146-157
Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A [¹¹C]PBR28 PET study
Tamm S; Cervenka S; Forsberg A; Estelius J; Grunewald J; Gyllfors P; Karshikoff B; Kosek E; Lampa J; Lensmar C; Strand V; Akerstedt T; Halldin C; Ingvar M; Hoglund CO; Lekander M
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2017;66:e33
Change in sickness behavior assessed with the Sickness Questionnaire after endotoxin challenge is associated with the degree of change in inflammatory cytokines
Andreasson A; Lasselin J; Karshikoff B; Olsson MJ; Axelsson J; Lekander M
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2017;66:e34
Seasonal variation in central and peripheral inflammation in allergic subjects: A PET study
Lekander M; Tamm S; Cervenka S; Forsberg A; Lensmar C; Kosek E; Lampa J; Estelius J; Karshikoff B; Ingvar M; Höglund CO
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2017;66:e33
Changes in self-rated health after endotoxin stimulation correlate with changes in cytokines and sickness behavior
Andreasson A; Lasselin J; Karshikoff B; Olsson MJ; Axelsson J; Lekander M
Article: NEUROPSYCHOPHARMACOLOGY. 2017;42(4):801-810
Lipopolysaccharide Alters Motivated Behavior in a Monetary Reward Task: a Randomized Trial
Lasselin J; Treadway MT; Lacourt TE; Soop A; Olsson MJ; Karshikoff B; Paues-Goranson S; Axelsson J; Dantzer R; Lekander M
Article: JOURNAL OF ABNORMAL PSYCHOLOGY. 2016;125(7):868-878
Health Anxiety in a Disease-Avoidance Framework: Investigation of Anxiety, Disgust and Disease Perception in Response to Sickness Cues
Hedman E; Lekander M; Karshikoff B; Ljotsson B; Axelsson E; Axelsson J
Article: BRAIN BEHAVIOR AND IMMUNITY. 2016;57:30-37
Mood disturbance during experimental endotoxemia: Predictors of state anxiety as a psychological component of sickness behavior
Lasselin J; Elsenbruch S; Lekander M; Axelsson J; Karshikoff B; Grigoleit J-S; Engler H; Schedlowski M; Benson S
Article: BRAIN BEHAVIOR AND IMMUNITY. 2016;57:38-46
Why sickness hurts: A central mechanism for pain induced by peripheral inflammation
Karshikoff B; Jensen KB; Kosek E; Kalpouzos G; Soop A; Ingvar M; Hoglund CO; Lekander M; Axelsson J
Article: BRAIN BEHAVIOR AND IMMUNITY. 2016;56:34-41
Intrinsic functional connectivity of insular cortex and symptoms of sickness during acute experimental inflammation
Lekander M; Karshikoff B; Johansson E; Soop A; Fransson P; Lundstrom JN; Andreasson A; Ingvar M; Petrovic P; Axelsson J; Nilsonne G
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2015;49:e1
LPS increases pain sensitivity by decreased pain inhibition and increased insular activation
Karshikoff B; Jensen KB; Ingvar M; Kosek E; Kalpouzos G; Soop A; Höglund CO; Lekander M; Axelsson J
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2015;49:e29-e30
Pre-existent anxiety symptoms is associated with modified behavioral response during endotoxemia
Lasselin J; Lekander M; Axelsson J; Karshikoff B; Engler H; Elsenbruch S; Grigoleit J; Benson S
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2015;49:e47
Is health anxiety related to disease avoidance?
Axelsson J; Lekander M; Karshikoff B; Hedman E
Article: BRAIN BEHAVIOR AND IMMUNITY. 2015;48:53-56
Sick man walking: Perception of health status from body motion
Sundelin T; Karshikoff B; Axelsson E; Hoglund CO; Lekander M; Axelsson J
Article: BRAIN BEHAVIOR AND IMMUNITY. 2015;46:35-43
Modality and sex differences in pain sensitivity during human endotoxemia
Karshikoff B; Lekander M; Soop A; Lindstedt F; Ingvar M; Kosek E; Hoglund CO; Axelsson J
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2014;40:e42
146. Effects of low-dose LPS on resting-state fMRI network activity
Lekander M; Karshikoff B; Nilsonne G; Ingvar M; Johansson E; Lundström J; Åkerstedt T; Höglund CO; Axelsson J
Article: PSYCHOLOGICAL SCIENCE. 2014;25(3):817-823
The Scent of Disease Human Body Odor Contains an Early Chemosensory Cue of Sickness
Olsson MJ; Lundstrom JN; Kimball BA; Gordon AR; Karshikoff B; Hosseini N; Sorjonen K; Hoglund CO; Solares C; Soop A; Axelsson J; Lekander M
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2013;32:e34
117. Self-rated health in response to experimental manipulations of inflammation is mediated by sickness behavior as assessed by the sickness questionnaire
Lidberg L; Andreasson AN; Karshikoff B; Axelsson J; Höglund CO; Lekander M
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2013;32:e32
110. Pain sensitivity during experimentally induced systemic inflammation in humans
Karshikoff B; Lekander M; Höglund CO; Axelsson J
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2013;32:e14
49. Development and preliminary validation of the Sickness Questionnaire (SicknessQ)
Andreasson AN; Wicksell R; Karshikoff B; Lodin K; Axelsson J; Höglund CO; Lekander M
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(10):2401-2412
Allergy influences the inflammatory status of the brain and enhances tau-phosphorylation
Sarlus H; Hoglund CO; Karshikoff B; Wang X; Lekander M; Schultzberg M; Oprica M
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2012;26:s46
165. The perception of disease: Does a systemic inflammation affect odor, looks and biological movement?
Axelsson J; Karshikoff B; Sundelin T; Höglund CO; Soop A; Olsson M; Lekander M
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2012;26:s18
62. Sickness hurts: Pain sensitivity during human endotoxemia
Karshikoff B; Lekander M; Lindstedt F; Sahlander K; Kramar M; Soop A; Bachrach T; Kosek E; Ingvar M; Höglund CO; Axelsson J
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2012;26:s48
171. Self-rated health in response to experimental manipulations of inflammation
Lekander M; Andreasson AN; Karshikoff B; Lidberg L; Axelsson J; Höglund CO
Article: PLOS ONE. 2012;7(8):e43221
Serotonin-1A Receptor Polymorphism (rs6295) Associated with Thermal Pain Perception
Lindstedt F; Karshikoff B; Schalling M; Hoglund CO; Ingvar M; Lekander M; Kosek E
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2011;25:s198
Sickness hurts: Human pain sensitivity in response to experimental inflammatory stimulation
Lekander M; Karshikoff B; Ingvar M; Kosek E; Soop A; Höglund CO; Axelsson J
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Alla övriga publikationer

Review: NEUROIMMUNOMODULATION. 2023;30(1):250-267
How can experimental endotoxemia contribute to our understanding of pain? A narrative review
Benson S; Karshikoff B
Editorial comment: BRAIN BEHAVIOR AND IMMUNITY. 2022;106:227-230
Editorial: Vulnerability and protective factors for inflammation-associated somatoform and mental disorders
Karshikoff B; Lekander M; Lasselin J
Editorial comment: FRONTIERS IN PSYCHIATRY. 2021;12:735337
Editorial: The Different Faces of Sickness
Rademacher L; Lasselin J; Karshikoff B; Hundt JE; Engler H; Lange T
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2020;115:15-24
Comparison of bacterial lipopolysaccharide-induced sickness behavior in rodents and humans: Relevance for symptoms of anxiety and depression
Lasselin J; Schedlowski M; Karshikoff B; Engler H; Lekander M; Konsman JP
Review: CURRENT OPINION IN BEHAVIORAL SCIENCES. 2019;28:85-92
Neuroimmune modulation of pain across the developmental spectrum
Karshikoff B; Tadros MA; Mackey S; Zouikr I
Conference publication: BRAIN BEHAVIOR AND IMMUNITY. 2019;76:e12-e13
Impaired cognition and fatigue; the role of sleep and neuroinflammation for non-specific symptoms in allergy
Tamm SR; Cervenka S; Forsberg A; Estelius J; Grunewald J; Gyllfors P; Karshikoff B; Kosek E; Lampa J; Lensmar C; Strand V; Akerstedt T; Halldin C; Ingvar M; Hoglund CO; Lekander M
Review: FRONTIERS IN NEUROENDOCRINOLOGY. 2018;50:91-106
Sex differences in how inflammation affects behavior: What we can learn from experimental inflammatory models in humans
Lasselin J; Lekander M; Axelsson J; Karshikoff B
Review: FRONTIERS IN IMMUNOLOGY. 2017;8:21
Role of inflammation in Human Fatigue: Relevance of Multidimensional Assessments and Potential Neuronal Mechanisms
Karshikoff B; Sundelin T; Lasselin J
Review: FRONTIERS IN IMMUNOLOGY. 2017;8:276
Lifetime Modulation of the Pain System via Neuroimmune and Neuroendocrine interactions
Zouikr I; Karshikoff B
Conference publication: BRAIN BEHAVIOR AND IMMUNITY. 2016;57:E41-E42
Sickness behavior mediates the effects of inflammation on self-rated health
Karshikoff BA; Andreasson A; Axelsson J; Lekander M
Thesis / dissertation: 2015
Sickness behavior : immune system influences on brain and behavior
Karshikoff, Bianka
Conference publication: CHEMICAL SENSES. 2015;40(3):254
The scent of disease
Gordon AR; Karshikoff B; Kimball BA; Lundstroem JN; Soop A; Sorjonen K; Lekander M; Axelsson J; Olsson MJ
Conference publication: 2012;:a1345
Does Sickness Hurt? A Study On Human Pain Sensitivity In Experimental Endotoxemia
Sahlander K; Karshikoff B; Kramar M; Ingvar M; Kosek E; Soop A; Axelsson J; Lekander M; Höglund CO
Conference publication: CHEMICAL SENSES. 2011;36(1):E49
The smell of disease: Human body odor changes in response to systemic inflammation
Olsson MJ; Hosseini N; Brodin M; Lundstrom JN; Soop A; Lekander M; Axelsson J; Karshikoff B

Forskningsbidrag

Changes in the central nervous system induced by allergic asthma that relate to depression and pain
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2020
The Significance of Inflammation in Cognitive Behavioral Treatment of Chronic Pain
Council for International Exchange of Scholars
1 September 2017 - 30 September 2018
Exploring the interface between the immune system and behavior: The effect of inflammation on cognitive behavioral treatment of chronic pain
Swedish Research Council
1 July 2017 - 30 June 2020
Resebidrag: Resebidrag: Brain, Behavior and Immunity in Health and Disease, San Diego, USA, 7-9 juni 2012
Swedish Research Council for Health Working Life and Welfare
1 May 2012 - 30 June 2012

Anställningar

Lector, Psykologi, Department of Social Studies, University of Stavanger, 2021-
Anknuten till Forskning, Klinisk neurovetenskap, Karolinska Institutet, 2024-2027

Examina och utbildning

Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2015

Om mig

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI