Bengt Fadeel

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Bengt Fadeel är leg. läkare och professor i medicinsk inflammationsforskning

samt vice prefekt vid Institutet för miljömedicin (IMM) vid Karolinska Institutet.
Prof. Fadeel är ledamot av The Academy of Toxicological Sciences (ATS) (2012)
samt Academia Europaea (Class of Biochemistry and Molecular Biology) (2024).

Forskningsbeskrivning

För information om Bengt Fadeels verksamhet, se Enheten för molekylär toxikologi.

Utvalda publikationer

Article: NANO TODAY. 2024;54:102084
Immune profiling and tracking of two-dimensional transition metal dichalcogenides in cells and tissues
Gazzi A; Fusco L; Orecchioni M; Keshavan S; Shin Y; Grivel J-C; Rinchai D; Ahmed EI; Elhanani O; Furesi G; Rauner M; Keren L; Ley K; Casiraghi C; Bedognetti D; Fadeel B; Delogu LG
Article: MATTER. 2024;7(1):191-215
Tuning the transformation and cellular signaling of 2D titanium carbide MXenes using a natural antioxidant
Malina T; Hamawandi B; Toprak MS; Chen L; Bjork J; Zhou J; Rosen J; Fadeel B
Article: ACS NANO. 2023;17(17):17451-17467
Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation
Gupta G; Kaur J; Bhattacharya K; Chambers BJ; Gazzi A; Furesi G; Rauner M; Fuoco C; Orecchioni M; Delogu LG; Haag L; Stehr JE; Thomen A; Bordes R; Malmberg P; Seisenbaeva GA; Kessler VG; Persson M; Fadeel B
Article: NATURE NANOTECHNOLOGY. 2023;18(1):42-48
Graphene oxide elicits microbiome-dependent type 2 immune responses via the aryl hydrocarbon receptor
Peng G; Sinkko HM; Alenius H; Lozano N; Kostarelos K; Brautigam L; Fadeel B
Article: NATURE COMMUNICATIONS. 2022;13(1):3798
Biomarkers of nanomaterials hazard from multi-layer data
Fortino V; Kinaret PAS; Fratello M; Serra A; Saarimaki LA; Gallud A; Gupta G; Vales G; Correia M; Rasool O; Ytterberg J; Monopoli M; Skoog T; Ritchie P; Moya S; Vazquez-Campos S; Handy R; Grafstrom R; Tran L; Zubarev R; Lahesmaa R; Dawson K; Loeschner K; Larsen EH; Krombach F; Norppa H; Kere J; Savolainen K; Alenius H; Fadeel B; Greco D
Article: SMALL. 2022;18(20):e2107816
2D Transition Metal Dichalcogenides Trigger Trained Immunity in Human Macrophages through Epigenetic and Metabolic Pathways
Peng G; Keshavan S; Delogu L; Shin Y; Casiraghi C; Fadeel B
Article: SMALL. 2020;16(21):e1907686
Next-Generation Sequencing Reveals Differential Responses to Acute versus Long-Term Exposures to Graphene Oxide in Human Lung Cells
Mukherjee SP; Gupta G; Kloditz K; Wang J; Rodrigues AF; Kostarelos K; Fadeel B
Article: NATURE NANOTECHNOLOGY. 2018;13(7):537-543
Advanced tools for the safety assessment of nanomaterials
Fadeel B; Farcal L; Hardy B; Vazquez-Campos S; Hristozov D; Marcomini A; Lynch I; Valsami-Jones E; Alenius H; Savolainen K
Article: CHEM. 2018;4(2):334-358
Graphene Oxide Elicits Membrane Lipid Changes and Neutrophil Extracellular Trap Formation
Mukherjee SP; Lazzaretto B; Hultenby K; Newman L; Rodrigues AF; Lozano N; Kostarelos K; Malmberg P; Fadeel B
Article: SCIENCE SIGNALING. 2015;8(395):ra95
Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity
Balasubramanian K; Maeda A; Lee JS; Mohammadyani D; Dar HH; Jiang JF; Croix CMS; Watkins S; Tyurin VA; Tyurina YY; Kloeditz K; Polimova A; Kapralova VI; Xiong Z; Ray P; Klein-Seetharaman J; Mallampalli RK; Bayir H; Fadeel B; Kagan VE
Article: NATURE NANOTECHNOLOGY. 2010;5(5):354-359
Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation
Kagan VE; Konduru NV; Feng W; Allen BL; Conroy J; Volkov Y; Vlasova II; Belikova NA; Yanamala N; Kapralov A; Tyurina YY; Shi J; Kisin ER; Murray AR; Franks J; Stolz D; Gou P; Klein-Seetharaman J; Fadeel B; Star A; Shvedova AA

Artiklar

Journal article: ADVANCED HEALTHCARE MATERIALS. 2024;:e2401783
Biocompatibility of Water-Dispersible Pristine Graphene and Graphene Oxide Using a Close-to-Human Animal Model: A Pilot Study on Swine
Nicolussi P; Pilo G; Cancedda MG; Peng G; Chau NDQ; de la Cadena A; Vanna R; Samad YA; Ahmed T; Marcellino J; Tedde G; Giro L; Ylmazer A; Loi F; Carta G; Secchi L; Dei Giudici S; Macciocu S; Polli D; Nishina Y; Ligios C; Cerullo G; Ferrari A; Bianco A; Fadeel B; Franzoni G; Delogu LG
Journal article: CHEMOSPHERE. 2024;366:143513
Putting advanced materials to the test: Ti3C2 MXenes alleviate the hazardous effects of the environmental pollutant benzo[a]pyrene.
Kaur J; Khort A; Sadiktsis I; Preethika M; Bird JRT; Barg S; Odnevall I; Fadeel B
Journal article: ADVANCED SCIENCE. 2024;11(32):e2400389
A Network Toxicology Approach for Mechanistic Modelling of Nanomaterial Hazard and Adverse Outcomes
del Giudice G; Serra A; Pavel A; Torres Maia M; Saarimaki LA; Fratello M; Federico A; Alenius H; Fadeel B; Greco D
Article: JOURNAL OF HAZARDOUS MATERIALS. 2024;473:134686
Hazard assessment of hexagonal boron nitride and hexagonal boron nitride reinforced thermoplastic polyurethane composites using human skin and lung cells
Carlin M; Kaur J; Ciobanu DZ; Song Z; Olsson M; Totu T; Gupta G; Peng G; Gonzalez VJ; Janica I; Pozo VF; Chortarea S; Buljan M; Buerki-Thurnherr T; Castillo AEDR; Thorat SB; Bonaccorso F; Tubaro A; Vazquez E; Prato M; Armirotti A; Wick P; Bianco A; Fadeel B; Pelin M
Article: SMALL. 2024;20(28):e2310540
Nanosafety: a Perspective on Nano-Bio Interactions
Fadeel B; Keller AA
Article: NANOSCALE ADVANCES. 2024;6(9):2419-2430
Cytotoxicity assessment of exfoliated MoS₂ using primary human mast cells and the progenitor cell-derived mast cell line LAD2
Lin H; Castillo AEDR; Gonzalez VJ; Bonaccorso F; Vazquez E; Fadeel B; Bianco A
Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2024;55:102714
Exploiting the ferroaddiction of pancreatic cancer cells using Fe-doped nanoparticles
Lomphithak T; Sae-Fung A; Sprio S; Tampieri A; Jitkaew S; Fadeel B
Journal article: CURRENT OPINION IN TOXICOLOGY. 2023;36:100427
2D materials and the microbiome: More than a gut feeling
Peng G; Fadeel B
Article: NANOSCALE. 2023;15(43):17409-17421
Two-dimensional molybdenum disulfide nanosheets evoke nitric oxide-dependent antibacterial effects
Peng G; Gonzalez V; Vazquez E; Lundberg JO; Fadeel B
Article: NANOSCALE ADVANCES. 2023;5(13):3453-3462
Label-free detection of polystyrene nanoparticles in Daphnia magna using Raman confocal mapping
Kaur J; Kelpsiene E; Gupta G; Dobryden I; Cedervall T; Fadeel B
Article: NANOMATERIALS. 2023;13(11):1719
High-Dose Exposure to Polymer-Coated Iron Oxide Nanoparticles Elicits Autophagy-Dependent Ferroptosis in Susceptible Cancer Cells
Lomphithak T; Helvacioglu S; Armenia I; Keshavan S; Ovejero JG; Baldi G; Ravagli C; Grazu V; Fadeel B
Article: PLOS ONE. 2023;18(9):e0288737
Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay
Fontaine M; Bartolami E; Prono M; Beal D; Blosi M; Costa AL; Ravagli C; Baldi G; Sprio S; Tampieri A; Fenoglio I; Tran L; Fadeel B; Carriere M
Article: FRONTIERS IN TOXICOLOGY. 2023;5:1254748
Don't sweat the small stuff: a conversation about nanosafety
Fadeel B; Sayre P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2022;633:45-51
Nanomaterial characterization: Understanding nano-bio interactions
Fadeel B
Article: JOURNAL OF HAZARDOUS MATERIALS. 2022;435:129053
Hazard assessment of abraded thermoplastic composites reinforced with reduced graphene oxide
Chortarea S; Kuru OC; Netkueakul W; Pelin M; Keshavan S; Song Z; Ma B; Gomes J; Villaro Abalos E; de Luna LAV; Loret T; Fordham A; Drummond M; Kontis N; Anagnostopoulos G; Paterakis G; Cataldi P; Tubaro A; Galiotis C; Kinloch I; Fadeel B; Bussy C; Kostarelos K; Buerki-Thurnherr T; Prato M; Bianco A; Wick P
Article: PARTICLE AND FIBRE TOXICOLOGY. 2022;19(1):33
Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)
Gupta G; Cappellini F; Farcal L; Gornati R; Bernardini G; Fadeel B
Article: FRONTIERS IN TOXICOLOGY. 2022;4:974429
Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials
Martin S; de Haan L; Estruch IM; Eder KM; Marzi A; Schnekenburger J; Blosi M; Costa A; Antonello G; Bergamaschi E; Riganti C; Beal D; Carriere M; Tache O; Hutchison G; Malone E; Young L; Campagnolo L; La Civita F; Pietroiusti A; Devineau S; Baeza A; Boland S; Zong C; Ichihara G; Fadeel B; Bouwmeester H
Article: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2022;10:1083232
Silver nanoparticles with excellent biocompatibility block pseudotyped SARS-CoV-2 in the presence of lung surfactant
Gupta G; Hamawandi B; Sheward DJ; Murrell B; Hanke L; McInerney G; Blosi M; Costa AL; Toprak MS; Fadeel B
Article: NANOTOXICOLOGY. 2021;15(9):1125-1150
Multi-walled carbon nanotubes trigger lysosome-dependent cell death (pyroptosis) in macrophages but not in neutrophils
Keshavan S; Gupta G; Martin S; Fadeel B
Article: NANOSCALE. 2021;13(30):13072-13084
Biodegradation of graphdiyne oxide in classically activated (M1) macrophages modulates cytokine production
Peng G; Duan T; Guo M; Xue Y; Chen C; Li Y; Leifer K; Fadeel B
Article: CARBON. 2021;178:563-572
Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice
Scala G; Delaval MN; Mukherjee SP; Federico A; Khaliullin TO; Yanamala N; Fatkhutdinova LM; Kisin ER; Greco D; Fadeel B; Shvedova AA
Article: ADVANCED SCIENCE. 2021;8(10):2004588
Toxicogenomic Profiling of 28 Nanomaterials in Mouse Airways
Kinaret PAS; Ndika J; Ilves M; Wolff H; Vales G; Norppa H; Savolainen K; Skoog T; Kere J; Moya S; Handy RD; Karisola P; Fadeel B; Greco D; Alenius H
Article: NANOIMPACT. 2021;22:100313
Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles
Gosens I; Costa PM; Olsson M; Stone V; Costa AL; Brunelli A; Badetti E; Bonetto A; Bokkers BGH; de Jong WH; Williams A; Halappanavar S; Fadeel B; Cassee FR
Article: NANOMEDICINE. 2021;16(9):689-707
Efficacy, biocompatibility and degradability of carbon nanoparticles for photothermal therapy of lung cancer
Kokalari I; Keshavan S; Rahman M; Gazzano E; Barzan G; Mandrile L; Giovannozzi A; Ponti J; Antonello G; Monopoli M; Perrone G; Bergamaschi E; Riganti C; Fadeel B; Fenoglio I
Article: NANOMATERIALS. 2021;11(4):883
Profiling of Sub-Lethal in Vitro Effects of Multi-Walled Carbon Nanotubes Reveals Changes in Chemokines and Chemokine Receptors
Keshavan S; Torres Andon F; Gallud A; Chen W; Reinert K; Tran L; Fadeel B
Article: FRONTIERS IN TOXICOLOGY. 2021;3:735331
Development of Microfluidic, Serum-Free Bronchial Epithelial Cells-on-a-Chip to Facilitate a More Realistic In vitro Testing of Nanoplastics
Gupta G; Vallabani S; Bordes R; Bhattacharya K; Fadeel B
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2021;192(1):200-211
Severe congenital neutropenia-associated JAGN1 mutations unleash a calpain-dependent cell death programme in myeloid cells
Khandagale A; Holmlund T; Entesarian M; Nilsson D; Kalwak K; Klaudel-Dreszler M; Carlsson G; Henter J-I; Nordenskjold M; Fadeel B
Journal article: PRECISION NANOMEDICINE. 2020;3(4):709
Comment on “The long life of unicorns”
Fadeel B
Article: ADVANCED SCIENCE. 2020;7(22):2002221
Multiparametric Profiling of Engineered Nanomaterials: Unmasking the Surface Coating Effect
Gallud A; Delaval M; Kinaret P; Marwah VS; Fortino V; Ytterberg J; Zubarev R; Skoog T; Kere J; Correia M; Loeschner K; Al-Ahmady Z; Kostarelos K; Ruiz J; Astruc D; Monopoli M; Handy R; Moya S; Savolainen K; Alenius H; Greco D; Fadeel B
Article: MATERIALS. 2020;13(20):E4532-4532
Risk Management Framework for Nano-Biomaterials Used in Medical Devices and Advanced Therapy Medicinal Products
Giubilato E; Cazzagon V; Amorim MJB; Blosi M; Bouillard J; Bouwmeester H; Costa AL; Fadeel B; Fernandes TF; Fito C; Hauser M; Marcomini A; Nowack B; Pizzol L; Powell L; Prina-Mello A; Sarimveis H; Scott-Fordsmand JJ; Semenzin E; Stahlmecke B; Stone V; Vignes A; Wilkins T; Zabeo A; Tran L; Hristozov D
Article: NANOSCALE. 2020;12(32):16730-16737
Nitric oxide-dependent biodegradation of graphene oxide reduces inflammation in the gastrointestinal tract
Peng G; Montenegro MF; Ntola CNM; Vranic S; Kostarelos K; Vogt C; Toprak MS; Duan T; Leifer K; Brautigam L; Lundberg JO; Fadeel B
Article: JOURNAL OF PHYSICS-MATERIALS. 2020;3(3):034009
Graphene, other carbon nanomaterials and the immune system: toward nanoimmunity-by-design
Gazzi A; Fusco L; Orecchioni M; Ferrari S; Franzoni G; Yan JS; Rieckher M; Peng G; Lucherelli MA; Anna Vacchi I; Ngoc DQC; Criado A; Istif A; Mancino D; Dominguez A; Eckert H; Vazquez E; Da Ros T; Nicolussi P; Palermo V; Schumacher B; Cuniberti G; Mai Y; Clementi C; Pasquali M; Feng X; Kostarelos K; Yilmazer A; Bedognetti D; Fadeel B; Prato M; Bianco A; Delogu LG
Article: ADVANCED SCIENCE. 2020;7(12):1903200
Size-Dependent Pulmonary Impact of Thin Graphene Oxide Sheets in Mice: Toward Safe-by-Design
Rodrigues AF; Newman L; Jasim D; Mukherjee SP; Wang J; Vacchi IA; Menard-Moyon C; Bianco A; Fadeel B; Kostarelos K; Bussy C
Article: CARBON. 2020;159:598-610
Keratinocytes are capable of selectively sensing low amounts of graphene-based materials: Implications for cutaneous applications
Fusco L; Pelin M; Mukherjee S; Keshavan S; Sosa S; Martin C; Gonzalez V; Vazquez E; Prato M; Fadeel B; Tubaro A
Article: FASEB JOURNAL. 2020;34(4):5262-5281
Cobalt nanoparticles trigger ferroptosis-like cell death (oxytosis) in neuronal cells: Potential implications for neurodegenerative disease
Gupta G; Gliga A; Hedberg J; Serra A; Greco D; Odnevall Wallinder I; Fadeel B
Article: NANOSCALE ADVANCES. 2020;2(2):648-658
Silver nanoparticles modulate lipopolysaccharide-triggered Toll-like receptor signaling in immune-competent human cell lines
Gliga AR; De Loma J; Di Bucchianico S; Skoglund S; Keshavan S; Odnevall Wallinder I; Karlsson HL; Fadeel B
Article: FRONTIERS IN TOXICOLOGY. 2020;2:4
Covid-19 Misinformation Alert, or: "Wash Your Hands and Eat Your Veggies!"
Fadeel B
Article: NANOSCALE. 2019;11(45):22006-22018
Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer
Madamsetty VS; Pal K; Keshavan S; Caulfield TR; Dutta SK; Wang E; Fadeel B; Mukhopadhyay D
Article: JOURNAL OF IMMUNOLOGY. 2019;203(8):2276-2290
Intra- and Extracellular Degradation of Neutrophil Extracellular Traps by Macrophages and Dendritic Cells
Lazzaretto B; Fadeel B
Journal article: NATURE NANOTECHNOLOGY. 2019;14(9):902
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.
Leong HS; Butler KS; Brinker CJ; Azzawi M; Conlan S; Dufès C; Owen A; Rannard S; Scott C; Chen C; Dobrovolskaia MA; Kozlov SV; Prina-Mello A; Schmid R; Wick P; Caputo F; Boisseau P; Crist RM; McNeil SE; Fadeel B; Tran L; Hansen SF; Hartmann NB; Clausen LPW; Skjolding LM; Baun A; Ågerstrand M; Gu Z; Lamprou DA; Hoskins C; Huang L; Song W; Cao H; Liu X; Jandt KD; Jiang W; Kim BYS; Wheeler KE; Chetwynd AJ; Lynch I; Moghimi SM; Nel A; Xia T; Weiss PS; Sarmento B; das Neves J; Santos HA; Santos L; Mitragotri S; Little S; Peer D; Amiji MM; Alonso MJ; Petri-Fink A; Balog S; Lee A; Drasler B; Rothen-Rutishauser B; Wilhelm S; Acar H; Harrison RG; Mao C; Mukherjee P; Ramesh R; McNally LR; Busatto S; Wolfram J; Bergese P; Ferrari M; Fang RH; Zhang L; Zheng J; Peng C; Du B; Yu M; Charron DM; Zheng G; Pastore C
Article: ADVANCED FUNCTIONAL MATERIALS. 2019;29(39)
A Biodegradable Multifunctional Graphene Oxide Platform for Targeted Cancer Therapy
Martin C; Ruiz A; Keshavan S; Reina G; Murera D; Nishina Y; Fadeel B; Bianco A
Journal article: NATURE NANOTECHNOLOGY. 2019;14(8):811
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.
Leong HS; Butler KS; Brinker CJ; Azzawi M; Conlan S; Dufès C; Owen A; Rannard S; Scott C; Chen C; Dobrovolskaia MA; Kozlov SV; Prina-Mello A; Schmid R; Wick P; Caputo F; Boisseau P; Crist RM; McNeil SE; Fadeel B; Tran L; Hansen SF; Hartmann NB; Clausen LPW; Skjolding LM; Baun A; Ågerstrand M; Gu Z; Lamprou DA; Hoskins C; Huang L; Song W; Cao H; Liu X; Jandt KD; Jiang W; Kim BYS; Wheeler KE; Chetwynd AJ; Lynch I; Moghimi SM; Nel A; Xia T; Weiss PS; Sarmento B; Neves JD; Santos HA; Santos L; Mitragotri S; Little S; Peer D; Amiji MM; Alonso MJ; Petri-Fink A; Balog S; Lee A; Drasler B; Rothen-Rutishauser B; Wilhelm S; Acar H; Harrison RG; Mao C; Mukherjee P; Ramesh R; McNally LR; Busatto S; Wolfram J; Bergese P; Ferrari M; Fang RH; Zhang L; Zheng J; Peng C; Du B; Yu M; Charron DM; Zheng G; Pastore C
Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2019;18:112-121
Tumor selective uptake of drug-nanodiamond complexes improves therapeutic outcome in pancreatic cancer
Madamsetty VS; Sharma A; Toma M; Samaniego S; Gallud A; Wang E; Pal K; Mukhopadhyay D; Fadeel B
Article: FASEB JOURNAL. 2019;33(4):4962-4974
Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment
Zaman F; Zhao Y; Celvin B; Mehta HH; Wan J; Chrysis D; Ohlsson C; Fadeel B; Cohen P; Savendahl L
Article: SCIENTIFIC REPORTS. 2019;9(1):4366
Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study
Gallud A; Kloditz K; Ytterberg J; Ostberg N; Katayama S; Skoog T; Gogvadze V; Chen Y-Z; Xue D; Moya S; Ruiz J; Astruc D; Zubarev R; Kere J; Fadeel B
Article: JOURNAL OF CELL SCIENCE. 2019;132(5):jcs227660
Structure and function analysis of the C-elegans aminophospholipid translocase TAT-1
Chen Y-Z; Kloditz K; Lee E-S; Nguyen DP; Yuan Q; Johnson J; Lee-yow Y; Hall A; Mitani S; Xia N-S; Fadeel B; Xue D
Article: SCIENTIFIC REPORTS. 2019;9(1):179
INSIdE NANO: a systems biology framework to contextualize the mechanism-of-action of engineered nanomaterials
Serra A; Letunic I; Fortino V; Handy RD; Fadeel B; Tagliaferri R; Greco D
Article: CELL DEATH DISCOVERY. 2019;5:65
Three cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death
Kloditz K; Fadeel B
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2018;104(6):1199-1213
JAGN1 is required for fungal killing in neutrophil extracellular traps: Implications for severe congenital neutropenia
Khandagale A; Lazzaretto B; Carlsson G; Sundin M; Shafeeq S; Romling U; Fadeel B
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2018;57(36):11722-11727
Degradation of Single-Layer and Few-Layer Graphene by Neutrophil Myeloperoxidase
Kurapati R; Mukherjee SP; Martin C; Bepete G; Vazquez E; Penicaud A; Fadeel B; Bianco A
Journal article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2018;130(36):11896-11901
Degradation of Single‐Layer and Few‐Layer Graphene by Neutrophil Myeloperoxidase
Kurapati R; Mukherjee SP; Martín C; Bepete G; Vázquez E; Pénicaud A; Fadeel B; Bianco A
Article: PARTICLE AND FIBRE TOXICOLOGY. 2018;15(1):32
Calcium-dependent cyto- and genotoxicity of nickel metal and nickel oxide nanoparticles in human lung cells
Di Bucchianico S; Gliga AR; Akerlund E; Skoglund S; Wallinder IO; Fadeel B; Karlsson HL
Article: SCIENTIFIC REPORTS. 2018;8(1):6668
RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells
Gliga AR; Di Bucchianico S; Lindvall J; Fadeel B; Karlsson HL
Article: CHEMOSPHERE. 2018;196:482-493
Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution
Libalova H; Costa PM; Olsson M; Farcal L; Ortelli S; Blosi M; Topinka J; Costa AL; Fadeel B
Article: ADVANCED HEALTHCARE MATERIALS. 2018;7(6):e1700916
Nitric Oxide Dependent Degradation of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Implications for Intra-Articular Delivery
Bhattacharya K; Sacchetti C; Costa PM; Sommertune J; Brandner BD; Magrini A; Rosato N; Bottini N; Bottini M; Fadeel B
Article: JOURNAL OF APPLIED TOXICOLOGY. 2018;38(3):385-397
Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles
Costa PM; Gosens I; Williams A; Farcal L; Pantano D; Brown DM; Stone V; Cassee FR; Halappanavar S; Fadeel B
Article: ADVANCED HEALTHCARE MATERIALS. 2018;7(4)
Cytokine Profiling of Primary Human Macrophages Exposed to Endotoxin-Free Graphene Oxide: Size-Independent NLRP3 Inflammasome Activation
Mukherjee SP; Kostarelos K; Fadeel B
Article: SCIENTIFIC REPORTS. 2018;8(1):1115
Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors
Mukherjee SP; Bondarenko O; Kohonen P; Andon FT; Brzicova T; Gessner I; Mathur S; Bottini M; Calligari P; Stella L; Kisin E; Shvedova A; Autio R; Salminen-Mankonen H; Lahesmaa R; Fadeel B
Article: NANOSCALE. 2018;10(3):1180-1188
Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic
Mukherjee SP; Gliga AR; Lazzaretto B; Brandner B; Fielden M; Vogt C; Newman L; Rodrigues AF; Shao W; Fournier PM; Toprak MS; Star A; Kostarelos K; Bhattacharya K; Fadeel B
Article: 2D MATERIALS. 2018;5(3):035020
A blueprint for the synthesis and characterisation of thin graphene oxide with controlled lateral dimensions for biomedicine
Rodrigues AF; Newman L; Lozano N; Mukherjee SP; Fadeel B; Bussy C; Kostarelos K
Article: JOURNAL OF IMMUNOTOXICOLOGY. 2018;15(1):12-23
Fibrous nanocellulose, crystalline nanocellulose, carbon nanotubes, and crocidolite asbestos elicit disparate immune responses upon pharyngeal aspiration in mice
Park E-J; Khaliullin TO; Shurin MR; Kisin ER; Yanamala N; Fadeel B; Chang J; Shvedova AA
Article: SCIENTIFIC REPORTS. 2017;7(1):9284
Cerium oxide nanoparticles inhibit differentiation of neural stem cells
Gliga AR; Edoff K; Caputo F; Kallman T; Blom H; Karlsson HL; Ghibelli L; Traversa E; Ceccatelli S; Fadeel B
Article: NANOTOXICOLOGY. 2017;11(6):809-826
Cytotoxicity screening and cytokine profiling of nineteen nanomaterials enables hazard ranking and grouping based on inflammogenic potential
Bhattacharya K; Kilic G; Costa PM; Fadeel B
Article: LAKARTIDNINGEN. 2017;114:EIAA
[Nano for better or worse: opportunities and risks with nanotechnology].
Fadeel B
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):44
Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab
Ajeganova S; Tesfa D; Hgglund H; Fadeel B; Vedin I; Zignego AL; Palmblad J
Article: CHEMOSPHERE. 2017;171:671-680
Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: Cytotoxicity or inflammation?
Menas AL; Yanamala N; Farcas MT; Russo M; Friend S; Fournier PM; Star A; Iavicoli I; Shurin GV; Vogel UB; Fadeel B; Beezhold D; Kisin ER; Shvedova AA
Article: CARBON. 2017;113:243-251
Hollow carbon spheres trigger inflammasome-dependent IL-1β secretion in macrophages
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PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells
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Skeletal Mineralization Deficits and Impaired Biogenesis and Function of Chondrocyte-Derived Matrix Vesicles in Phospho1^-/- and Phospho1/P_it1 Double-Knockout Mice
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Single-Walled Carbon Nanotubes Inhibit the Cytochrome P450 Enzyme, CYP3A4
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Nanodrugs to target articular cartilage: An emerging platform for osteoarthritis therapy
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Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production
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Lactoperoxidase-mediated degradation of single-walled carbon nanotubes in the presence of pulmonary surfactant
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It takes two to tango: Understanding the interactions between engineered nanomaterials and the immune system
Farrera C; Fadeel B
Journal article: EUROPEAN JOURNAL OF NANOMEDICINE. 2015;7(3):143-151
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Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells
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Comprehensive In Vitro Toxicity Testing of a Panel of Representative Oxide Nanomaterials: First Steps towards an Intelligent Testing Strategy
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Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages
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The eNanoMapper database for nanomaterial safety information
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Enzymatic 'stripping' and degradation of PEGylated carbon nanotubes
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Shifting identities of metal oxide nanoparticles: Focus on inflammation
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Targeted uptake of folic acid-functionalized iron oxide nanoparticles by ovarian cancer cells in the presence but not in the absence of serum
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Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines
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Exploring the anti-apoptotic role of HAX-1 versus BCL-X_L in cytokine-dependent bone marrow-derived cells from mice
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Classification Framework for Graphene-Based Materials
Wick P; Louw-Gaume AE; Kucki M; Krug HF; Kostarelos K; Fadeel B; Dawson KA; Salvati A; Vazquez E; Ballerini L; Tretiach M; Benfenati F; Flahaut E; Gauthier L; Prato M; Bianco A
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Graphene Oxide Attenuates Th2-Type Immune Responses, but Augments Airway Remodeling and Hyperresponsiveness in a Murine Model of Asthma
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Bortezomib and IL-12 produce synergetic anti-multiple myeloma effects with reduced toxicity to natural killer cells
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Article: EXPERIMENTAL HEMATOLOGY. 2014;42(3):172-182
Proapoptotic effects of the novel proteasome inhibitor b-AP15 on multiple myeloma cells and natural killer cells
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Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release
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Dexamethasone differentially regulates Bcl-2 family proteins in human proliferative chondrocytes: Role of pro-apoptotic Bid
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The bio-nano-interface in predicting nanoparticle fate and behaviour in living organisms: towards grouping and categorising nanomaterials and ensuring nanosafety by design
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Applying quantitative structure-activity relationship approaches to nanotoxicology: Current status and future potential
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Oxidative Stress and Dermal Toxicity of Iron Oxide Nanoparticles In Vitro
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Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process
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Biodegradation of Single-Walled Carbon Nanotubes by Eosinophil Peroxidase
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Graphene Oxide, But Not Fullerenes, Targets Immunoproteasomes and Suppresses Antigen Presentation by Dendritic Cells
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NanoMiner - Integrative Human Transcriptomics Data Resource for Nanoparticle Research
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Requirement of Apoptotic Protease-Activating Factor-1 for Bortezomib-Induced Apoptosis but Not for Fas-Mediated Apoptosis in Human Leukemic Cells
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Gene Expression Profiling of Immune-Competent Human Cells Exposed to Engineered Zinc Oxide or Titanium Dioxide Nanoparticles
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Ovarian failure in HAX1-deficient patients: is there a gender-specific difference in pubertal development in severe congenital neutropenia or Kostmann disease?
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Incidence of severe congenital neutropenia in Sweden and risk of evolution to myelodysplastic syndrome/leukaemia
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Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition
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Pulmonary exposure to single-walled carbon nanotubes does not affect the early immune response against Toxoplasma gondii
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Adsorption of Surfactant Lipids by Single-Walled Carbon Nanotubes in Mouse Lung upon Pharyngeal Aspiration
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Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos
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Microsomal Glutathione Transferase 1 Protects Against Toxicity Induced by Silica Nanoparticles but Not by Zinc Oxide Nanoparticles
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Scythe cleavage during Fas (APO-1)-and staurosporine-mediated apoptosis
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Morphological properties of nanoporous folic acid materials and in vitro assessment of their biocompatibility
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Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers
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Differentiation-Promoting Culture of Competent and Noncompetent Keratinocytes Identifies Biomarkers for Head and Neck Cancer
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Linear-Dendritic Polymeric Amphiphiles as Carriers of Doxorubicin-In Vitro Evaluation of Biocompatibility and Drug Delivery
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Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice
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Ablation of the Pro-Apoptotic Protein Bax Protects Mice from Glucocorticoid-Induced Bone Growth Impairment
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AIF and Scythe (Bat3) Regulate Phosphatidylserine Exposure and Macrophage Clearance of Cells Undergoing Fas (APO-1)-Mediated Apoptosis
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Clear and present danger? Engineered nanoparticles and the immune system
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MAML1 Acts Cooperatively with EGR1 to Activate EGR1-Regulated Promoters: Implications for Nephrogenesis and the Development of Renal Cancer
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Mapping the Surface Adsorption Forces of Nanomaterials in Biological Systems
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Double-Edged Sword of Novel Anti-Cancer Treatment: Proteasome Inhibition in the Growth Plate Causes Impairment of Longitudinal Bone Growth
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Global Phospholipidomics Analysis Reveals Selective Pulmonary Peroxidation Profiles upon Inhalation of Single-Walled Carbon Nanotubes
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Water-Soluble Superparamagnetic Magnetite Nanoparticles with Biocompatible Coating for Enhanced Magnetic Resonance Imaging
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Late-Onset Neutropenia Following Rituximab Therapy in Rheumatic Diseases: Association With B Lymphocyte Depletion and Infections
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Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure
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Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution
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Efficient internalization of silica-coated iron oxide nanoparticles of different sizes by primary human macrophages and dendritic cells
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In search of the Holy Grail: Folate-targeted nanoparticles for cancer therapy
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Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos?
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Hematopoietic Stem Cell Transplantation in Severe Congenital Neutropenia
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Nanotoxicology: no small matter
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Article: MOLECULAR IMMUNOLOGY. 2010;47(14):2388-2396
The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells
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Programmed cell clearance: Molecular regulation of the elimination of apoptotic cell corpses and its role in the resolution of inflammation
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Clinical Presentation of Griscelli Syndrome Type 2 and Spectrum of RAB27A Mutations
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Size-dependent effects of tungsten carbide-cobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells
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Correction: Phosphatidylserine Targets Single-Walled Carbon Nanotubes to Professional Phagocytes In Vitro and In Vivo
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Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxicity
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Induction of caspase- and reactive oxygen species-independent phosphatidylserine externalization in primary human neutrophils: role in macrophage recognition and engulfment
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Phosphatidylserine Targets Single-Walled Carbon Nanotubes to Professional Phagocytes In Vitro and In Vivo
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Carlsson G; van't Hooft I; Melin M; Entesarian M; Laurencikas E; Nennesmo I; Trebinska A; Grzybowska E; Palmblad J; Dahl N; Nordenskjold M; Fadeel B; Henter J-I
Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2008;231(2):235-240
Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes
Shvedova AA; Kisin ER; Murray AR; Kommineni C; Castranova V; Fadeel B; Kagan VE
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;142(3):469-479
Syntaxin-11 is expressed in primary human monocytes/macrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG-opsonized target cells
Zhang S; Ma D; Wang X; Celkan T; Nordenskjoeld M; Henter J-I; Fadeel B; Zheng C
Article: PEDIATRIC BLOOD & CANCER. 2008;51(1):76-81
Incidence of Langerhans cell histiocytosis in children:: A population-based study
Stalemark H; Laurencikas E; Karis J; Gavhed D; Fadeel B; Henter J-I
Journal article: CURRENT IMMUNOLOGY REVIEWS. 2008;4(2):53-69
PROGRAMMED Cell Clearance: Molecular Mechanisms and Role in Autoimmune Disease, Chronic Inflammation, and Anti-Cancer Immune Responses
Witasp E; Kagan V; Fadeel B
Article: PEDIATRIC BLOOD & CANCER. 2008;50(5):1067-1069
Sequence analysis of the SRGN, AP3B1, ARF6, and SH2D1A genes in familial hemophagocytic lymphohistiocytosis
Ma D; Rudd E; Edner J; Gavhed S; Ramme KG; Fadeel B; Nordenskjoeld M; Henter J-I; Zheng C
Article: JOURNAL OF MEDICAL GENETICS. 2008;45(3):134-141
Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis
Rudd E; Bryceson YT; Zheng C; Edner J; Wood SM; Ramme K; Gavhed S; Gurgey A; Hellebostad M; Bechensteen AG; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I
Article: MEDICAL ONCOLOGY. 2008;25(4):374-379
Late-onset neutropenia associated with rituximab therapy: evidence for a maturation arrest at the (pro)myelocyte stage of granulopoiesis
Tesfa D; Gelius T; Sander B; Kimby E; Fadeel B; Palmblad J; Hagglund H
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;363(4):989-993
VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice
Zheng C; Skold MK; Li J; Nennesmo I; Fadeel B; Henter J-I
Article: HFSP JOURNAL. 2007;1(4):225-229
Fat(al) attraction: oxidized lipids act as "eat-me" signals
Fadeel B; Quinn P; Xue D; Kagan V
Article: CANCER RESEARCH. 2007;67(20):10078-10086
Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice
Zaman F; Menendez-Benito V; Eriksson E; Chagin AS; Takigawa M; Fadeel B; Dantuma NP; Chrysis D; Saevendahl L
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;360(1):263-268
Epstein-Barr virus-encoded LMP1 promotes cisplatin-induced caspase activation through JNK and NF-κB signaling pathways
Zhang X; Sanmun D; Hu L; Fadeel B; Ernberg I
Article: LEUKEMIA. 2007;21(5):1035-1043
Smac-mediated sensitization of human B-lymphoma cells to staurosporine- and lactacystin-triggered apoptosis is apoptosome-dependent
Sun Y; Ottosson A; Pervaiz S; Fadeel B
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;137(2):166-169
Low plasma levels of the protein pro-LL-37 as an early indication of severe disease in patients with chronic neutropenia
Karlsson J; Carlsson G; Ramme KG; Hagglund H; Nordenskjold M; Henter J-I; Palmblad J; Putsep K; Andersson M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(11):8498-8509
Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment - Implications for the resolution of inflammation
Tyurina YY; Basova LV; Konduru NV; Tyurin VA; Potapovich AI; Cai P; Bayir H; Stoyanovsky D; Pitt BR; Shvedova AA; Fadeel B; Kagan VE
Article: CLINICAL IMMUNOLOGY. 2007;122(3):349-355
Normal levels of constitutive and death receptor-mediated apoptosis of peripheral blood neutrophils from patients with chronic idiopathic neutropenia
Garwicz D; Palmblad J; Fadeel B
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;353(3):571-575
Assignment of the gene locus for severe congenital neutropenia to chromosome 1q22 in the original Kostmann family from Northern Sweden
Melin M; Entesarian M; Carlsson G; Garwicz D; Klein C; Fadeel B; Nordenskjold M; Palmblad J; Henter JI; Dahl N
Article: NATURE GENETICS. 2007;39(1):86-92
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
Klein C; Grudzien M; Appaswamy G; Germeshausen M; Sandrock I; Schaffer AA; Rathinam C; Boztug K; Schwinzer B; Rezaei N; Bohn G; Melin M; Carlsson G; Fadeel B; Dahl N; Palmblad J; Henter J-I; Zeidler C; Grimbacher B; Welte K
Article: LAKARTIDNINGEN. 2006;103(50-52):4022-4027
[Kostmann's syndrome largely elucidated--by Swedish research. 50 years since Rolf Kostmann's pioneering work on severe congenital neutropenia].
Carlsson G; Garwicz D; Nordenskjöld M; Fadeel B; Palmblad J; Henter J-I
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2006;134(6):640-644
Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation
Sanmun D; Garwicz D; Smith CIE; Palmblad J; Fadeel B
Article: HAEMATOLOGICA. 2006;91(5):589-595
Neutrophil elastase and granulocyte colony-stimulating factor receptor mutation analyses and leukemia evolution in severe congenital neutropenia patients belonging to the original Kostmann family in northern Sweden
Carlsson G; Aprikyan AAG; Ericson KG; Stein S; Makaryan V; Dale DC; Nordenskjold M; Fadeel B; Palmblad J; Hentera J-I
Article: JOURNAL OF MEDICAL GENETICS. 2006;43(4):e14
Spectrum and clinical implications of syntaxin 11 gene mutations in familial haemophagocytic lymphohistiocytosis:: association with disease-free remissions and haematopoietic malignancies -: art. no. e14
Rudd E; Ericson KG; Zheng C; Uysal Z; Özkan A; Gürgey A; Fadeel B; Nordenskjöld M; Henter JI
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2006;28(3):605-617
Combined spectral karyotyping, comparative genomic hybridization, and in vitro apoptyping of a panel of Burkitt's lymphoma-derived B cell lines reveals an unexpected complexity of chromosomal aberrations and a recurrence of specific abnormalities in chemoresistant cell lines
Karpova MB; Schoumans J; Blennow E; Ernberg I; Henter JI; Smirnov AF; Nordenskjöld M; Fadeel B
Article: CELL DEATH AND DIFFERENTIATION. 2006;13(3):360-362
PS externalization: from corpse clearance to drug delivery
Fadeel B; Xue D
Article: PEDIATRIC RESEARCH. 2006;59(2):281-286
Elevated serum levels of the decoy receptor osteoprotegerin in children with langerhans cell histiocytosis
Rosso DA; Karis J; Braier JL; Henter JI; Fadeel B
Article: INTERNATIONAL JOURNAL OF CANCER. 2006;118(1):246-252
Betulinic acid, a natural cytotoxic agent, fails to trigger apoptosis in human Burkitt's lymphoma-derived B-cell lines
Karpova MB; Sanmun D; Henter JI; Smirnov AF; Fadeel B
Article: CLINICAL CANCER RESEARCH. 2005;11(17):6291-6299
Antiapoptotic role of growth factors in the Myelodysplastic syndromes:: Concordance between in vitro and in vivo observations
Tehranchi R; Fadeel B; Schmidt-Mende J; Forsblom AM; Emanuelsson E; Jadersten M; Christensson B; Hast R; Howe RB; Samuelsson J; Zhivotovsky B; Hollström-Lindberg E
Article: BLOOD. 2005;106(1):247-253
Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes
Tehranchi R; Invernizzi R; Grandien A; Zhivotovsky B; Fadeel B; Forsblom AM; Travaglino E; Samuelsson J; Hast R; Nilsson L; Cazzola M; Wibom R; Hellström-Lindberg E
Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2005;27(6):301-306
Immunohistochemical detection of the apoptosis-related proteins FADD, FLICE, and FLIP in langerhans cell histiocytosis
Bank MI; Gudbrand C; Rengtved P; Carstensen H; Fadeel B; Henter JI; Petersen BL
Article: BLOOD. 2005;105(10):4070-4077
Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance
Sun Y; Orrenius S; Pervaiz S; Fadeel B
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;330(3):891-897
Vitamin D fails to prevent serum starvation- or staurosporine-induced apoptosis in human and rat osteosarcoma-derived cell lines
Witasp E; Gustafsson AC; Cotgreave I; Lind M; Fadeel B
Article: LAKARTIDNINGEN. 2005;102(18-19):1444-1446
[Enigmatic diseases in children. Still a lot of questions left in spite of great research progress on LCH and HLH].
Fadeel B; Trottestam H; Löfstedt M; Gavhed D; Henter J-I
Article: INTERNATIONAL JOURNAL OF CANCER. 2005;113(3):397-405
Epstein-Barr virus-encoded latent membrane protein 1 promotes stress-induced apoptosis upstream of caspase-2-dependent mitochondrial perturbation
Zhang XN; Uthaisang W; Hu LF; Ernberg IT; Fadeel B
Article: ANNALS OF NEUROLOGY. 2004;56(4):564-567
Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS
Zheng CY; Nennesmo I; Fadeel B; Henter JI
Article: BLOOD. 2004;104(6):1859-1866
An endothelial laminin isoform, laminin 8 (α4β1γ1), is secreted by blood neutrophils, promotes neutrophil migration and extravasation, and protects neutrophils from apoptosis
Wondimu Z; Geberhiwot T; Ingerpuu S; Juronen E; Xie X; Lindbom L; Doi M; Kortesmaa J; Thyboll J; Tryggvason K; Fadeel B; Patarroyo M
Article: CANCER LETTERS. 2004;208(2):171-178
VR-3848, a novel peptide derived from Euphobiaceae, induces mitochondria-dependent apoptosis in human leukemia cells
Uthaisang W; Reutrakul V; Krachangchaeng C; Wilairat P; Fadeel B
Article: BLOOD. 2004;103(9):3355-3361
Kostmann syndrome:: severe congenital neutropenia associated with defective expression of Bcl-2, constitutive mitochondrial release of cytochrome c, and excessive apoptosis of myeloid progenitor cells
Carlsson G; Aprikyan AAG; Tehranchi R; Dale DC; Porwit A; Hellström-Lindberg E; Palmblad J; Henter JI; Fadeel B
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(7):6056-6064
Lipid antioxidant, etoposide, inhibits phosphatidylserine externalization and macrophage clearance of apoptotic cells by preventing phosphatidylserine oxidation
Tyurina YY; Serinkan FB; Tyurin VA; Kini V; Yalowich JC; Schroit AJ; Fadeel B; Kagan VE
Article: FASEB JOURNAL. 2004;18(1):1-4
Buried alive: a novel approach to cancer treatment
Fadeel B; Orrenius S; Pervaiz S
Article: FEBS LETTERS. 2003;545(2-3):110-114
Phosphatidylserine exposure in Fas type I cells is mitochondria-dependent
Uthaisang W; Nutt LK; Orrenius S; Fadeel B
Article: BLOOD. 2003;101(3):1080-1086
Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors
Tehranchi R; Fadeel B; Forsblom AM; Christensson B; Samuelsson J; Zhivotovsky B; Hellstrom-Lindberg E
Article: HUMAN GENETICS. 2003;112(1):98-99
Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis
Ericson KG; Fadeel B; Andersson M; Gudmundsson GH; Gürgey A; Yalman N; Janka G; Nordenskjöld M; Henter JI
Article: VIROLOGY. 2002;304(2):330-341
Apoptosis modulation of Epstein-Barr virus-encoded latent membrane protein 1 in the epithelial cell line HeLa is stimulus-dependent
Zhang XN; Hu LF; Fadeel B; Ernberg IT
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(51):49965-49975
NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me₂SO-differentiated HL-60 cells -: Role in phagocytic clearance
Arroyo A; Modriansky M; Serinkan FB; Bello RI; Matsura T; Jiang JF; Tyurin VA; Tyurina YY; Fadeel B; Kagan VE
Article: JOURNAL OF IMMUNOLOGY. 2002;169(1):487-499
A role for oxidative stress in apoptosis:: Oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis
Kagan VE; Gleiss B; Tyurina YY; Tyurin VA; Elenström-Magnusson C; Liu SX; Serinkan FB; Arroyo A; Chandra J; Orrenius S; Fadeel B
Article: FEBS LETTERS. 2002;519(1-3):153-158
Fas-triggered phosphatidylserine exposure is modulated by intracellular ATP
Gleiss B; Gogvadze V; Orrenius S; Fadeel B
Article: LAKARTIDNINGEN. 2001;98(42):4613-4614
[Apoptosis--emperor's new clothes?].
Fadeel B
Article: LEUKEMIA. 2001;15(5):742-751
Granulocyte colony-stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts
Schmidt-Mende J; Tehranchi R; Forsblom AM; Joseph B; Christensson B; Fadeel B; Zhivotovsky B; Hellström-Lindberg E
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2001;112(3):714-726
Apoptosis in refractory anaemia with ringed sideroblasts is initiated at the stem cell level and associated with increased activation of caspases
Lindberg EH; Schmidt-Mende J; Forsblom AM; Christensson B; Fadeel B; Zhivotovsky B
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;68(3):590-597
Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis
Ericson KG; Fadeel B; Nilsson-Ardnor S; Söderhäll C; Samuelsson A; Janka G; Schneider M; Gürgey A; Yalman N; Révész T; Egeler RM; Jahnukainen K; Storm-Mathiesen I; Haraldsson A; Poole J; de Saint Basile G; Nordenskjöld M; Henter JI
Article: MEDICAL PRINCIPLES AND PRACTICE. 2000;9(3):151-163
The potential role of apoptosis in human disease
Fadeel B; Orrenius S; Zhivotovsky B
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;266(2):504-511
Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
Fadeel B; Gleiss B; Högstrand K; Chandra J; Wiedmer T; Sims PJ; Henter JI; Orrenius S; Samali A
Article: EXPERIMENTAL HEMATOLOGY. 1999;27(8):1322-1329
Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39
Hassan Z; Fadeel B; Zhivotovsky B; Hellström-Lindberg E
Article: BRITISH JOURNAL OF HAEMATOLOGY. 1999;106(2):406-415
Induction of apoptosis and caspase activation in cells obtained from familial haemophagocytic lymphohistiocytosis patients
Fadeel B; Orrenius S; Henter JI
Article: LEUKEMIA. 1999;13(5):719-728
Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells
Fadeel B; Hassan Z; Hellström-Lindberg E; Henter JI; Orrenius S; Zhivotovsky B
Journal article: BLOOD. 1998;92(12):4808-4818
Involvement of Caspases in Neutrophil Apoptosis: Regulation by Reactive Oxygen Species
Fadeel B; Åhlin A; Henter J-I; Orrenius S; Hampton MB
Article: BLOOD. 1998;92(12):4808-4818
Involvement of caspases in neutrophil apoptosis:: Regulation by reactive oxygen species
Fadeel B; Åhlin A; Henter JI; Orrenius S; Hampton MB
Article: INTERNATIONAL IMMUNOLOGY. 1998;10(2):131-140
A three-dimensional model of the Fas/APO-1 molecule: cross-reactivity of anti-Fas antibodies explained by structural mimicry of antigenic sites
Fadeel B; Lindberg J; Achour A; Chiodi F
Article: AIDS. 1997;11(10):1219-1225
Induction of apoptosis by primary HIV-1 isolates correlates with productive infection in peripheral blood mononuclear cells
Zhang YJ; Fadeel B; Hodara V; Fenyo EM
Article: INTERNATIONAL IMMUNOLOGY. 1997;9(2):201-209
Anti-Fas IgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate different biological effects in vitro
Fadeel B; Thorpe CJ; Yonehara S; Chiodi F
Article: INTERNATIONAL IMMUNOLOGY. 1995;7(12):1967-1975
Mapping of the linear site on the Fas/APO-1 molecule targeted by the prototypic anti-Fas mAb
Fadeel B; Thorpe CJ; Chiodi F
Journal article: REVIEWS IN MEDICAL VIROLOGY. 1995;5(2):105-119
HIV‐1 Infection of the brain: Which pathogenic mechanisms are relevant for tissue damage?
Elovaara I; Fadeel B; Chiodi F
Journal article: VIROLOGY. 1993;196(2):475-483
V3 SEQUENCES OF PAIRED HIV-1 ISOLATES FROM BLOOD AND CEREBROSPINAL-FLUID CLUSTER ACCORDING TO HOST AND SHOW VARIATION RELATED TO THE CLINICAL STAGE OF DISEASE
KEYS B; KARIS J; FADEEL B; VALENTIN A; NORKRANS G; HAGBERG L; CHIODI F
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Understanding the Role and Impact of Poly (Ethylene Glycol) (PEG) on Nanoparticle Formulation: Implications for COVID-19 Vaccines
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Review: ACTA PAEDIATRICA. 2021;110(11):2912-2920
Kostmann disease and other forms of severe congenital neutropenia
Fadeel B; Garwicz D; Carlsson G; Sandstedt B; Nordenskjold M
Editorial comment: ACTA PAEDIATRICA. 2021;110(10):2673-2674
Tribute to Jan-Inge Henter, the Paediatrician-Scientist
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Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):746-748
Nanomedicine: towards innovative solutions in the clinic
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Review: AUTOPHAGY. 2021;17(1):1-382
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
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Arnaune-Pelloquin L; Aroca A; Arroyo DS; Arsov I; Artero R; Asaro DML; Aschner M; Ashrafizadeh M; Ashur-Fabian O; Atanasov AG; Au AK; Auberger P; Auner HW; Aurelian L; Autelli R; Avagliano L; Avalos Y; Aveic S; Aveleira CA; AvinWittenberg T; Aydin Y; Ayton S; Ayyadevara S; Azzopardi M; Baba M; Backer JM; Backues SK; Bae D-H; Bae O-N; Bae SH; Baehrecke EH; Baek A; Baek S-H; Baek SH; Bagetta G; Bagniewska-Zadworna A; Bai H; Bai J; Bai X; Bai Y; Bairagi N; Baksi S; Balbi T; Baldari CT; Balduini W; Ballabio A; Ballester M; Balazadeh S; Balzan R; Bandopadhyay R; Banerjee S; Banerjee S; Bao Y; Baptista MS; Baracca A; Barbati C; Bargiela A; Barila D; Barlow PG; Barmada SJ; Barreiro E; Barreto GE; Bartek J; Bartel B; Bartolome A; Barve GR; Basagoudanavar SH; Bassham DC; Bast RCJ; Basu A; Batoko H; Batten I; Baulieu EE; Baumgarner BL; Bayry J; Beale R; Beau I; Beaumatin F; Bechara LRG; Beck GRJ; Beers MF; Begun J; Behrends C; Behrens GMN; Bei R; Bejarano E; Bel S; Behl C; Belaid A; Belgareh-Touze N; Bellarosa C; Belleudi F; Bello Perez M; Bello-Morales R; de Oliveira Beltran JS; Beltran S; Benbrook DM; Bendorius M; Benitez BA; Benito-Cuesta I; Bensalem J; Berchtold MW; Berezowska S; Bergamaschi D; Bergami M; Bergmann A; Berliocchi L; Berlioz-Torrent C; Bernard A; Berthoux L; Besirli CG; Besteiro S; Betin VM; Beyaert R; Bezbradica JS; Bhaskar K; Bhatia-Kissova I; Bhattacharya R; Bhattacharya S; Bhattacharyya S; Bhuiyan MS; Bhutia SK; Bi L; Bi X; Biden TJ; Bijian K; Billes VA; Binart N; Bincoletto C; Birgisdottir AB; Bjorkoy G; Blanco G; Blas-Garcia A; Blasiak J; Blomgran R; Blomgren K; Blum JS; Boada-Romero E; Boban M; BoeszeBattaglia K; Boeuf P; Boland B; Bomont P; Bonaldo P; Bonam SR; Bonfili L; Bonifacino JS; Boone BA; Bootman MD; Bordi M; Borner C; Bornhauser BC; Borthakur G; Bosch J; Bose S; Botana LM; Botas J; Boulanger CM; Boulton ME; Bourdenx M; Bourgeois B; Bourke NM; Bousquet G; Boya P; Bozhkov PV; Bozi LHM; Bozkurt TO; Brackney DE; Brandts CH; Braun RJ; Braus GH; Bravo-Sagua R; Bravo-San Pedro JM; Brest P; Bringer M-A; Briones-Herrera A; Broaddus VC; Brodersen P; Alvarez EMC; Brodsky JL; Brody SL; Bronson PG; Bronstein JM; Brown CN; Brown RE; Brum PC; Brumell JH; Brunetti-Pierri N; Bruno D; Bryson-Richardson RJ; Bucci C; Buchrieser C; Bueno M; Buitrago-Molina LE; Buraschi S; Buch S; Buchan JR; Buckingham EM; Budak H; Budini M; Bultynck G; Burada F; Burgoyne JR; Buron MI; Bustos V; Buttner S; Butturini E; Byrd A; Cabas I; Cabrera-Benitez S; Cadwell K; Cai J; Cai L; Cai Q; Cairo M; Calbet JA; Caldwell GA; Caldwell KA; Call JA; Calvani R; Calvo AC; Barrera MC-R; Camara NO; Camonis JH; Camougrand N; Campanella M; Campbell EM; Campbell-Valois F-X; Campello S; Campesi I; Campos JC; Camuzard O; Cancino J; de Almeida DC; Canesi L; Caniggia I; Canonico B; Canti C; Cao B; Caraglia M; Carames B; Carchman EH; Cardenal-Munoz E; Cardenas C; Cardenas L; Cardoso SM; Carew JS; Carle GF; Carleton G; Carloni S; Carmona-Gutierrez D; Carneiro LA; Carnevali O; Carosi JM; Carra S; 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Warnsmann V; Watada H; Watanabe E; Watchon M; Weaver TE; Wegrzyn G; Wehman AM; Wei H; Wei L; Wei T; Wei Y; Weiergraber OH; Weihl CC; Weindl G; Weiskirchen R; Wells A; Wen RH; Wen X; Werner A; Weykopf B; Wheatley SP; Whitton JL; Whitworth AJ; Wiktorska K; Wildenberg ME; Wileman T; Wilkinson S; Willbold D; Williams B; Williams RSB; Williams RL; Williamson PR; Wilson RA; Winner B; Winsor NJ; Witkin SS; Wodrich H; Woehlbier U; Wollert T; Wong E; Wong JH; Wong RW; Wong VKW; Wong WW-L; Wu A-G; Wu C; Wu J; Wu J; Wu KK; Wu M; Wu S-Y; Wu S; Wu S; Wu S; Wu WKK; Wu X; Wu X; Wu Y-W; Wu Y; Xavier RJ; Xia H; Xia L; Xia Z; Xiang G; Xiang J; Xiang M; Xiang W; Xiao B; Xiao G; Xiao H; Xiao H-T; Xiao J; Xiao L; Xiao S; Xiao Y; Xie B; Xie C-M; Xie M; Xie Y; Xie Z; Xie Z; Xilouri M; Xu C; Xu E; Xu H; Xu J; Xu J; Xu L; Xu WW; Xu X; Xue Y; Yakhine-Diop SMS; Yamaguchi M; Yamaguchi O; Yamamoto A; Yamashina S; Yan S; Yan S-J; Yan Z; Yanagi Y; Yang C; Yang D-S; Yang H; Yang H-T; Yang H; Yang J-M; Yang J; Yang J; Yang L; Yang L; Yang M; Yang P-M; Yang Q; Yang S; Yang S; Yang S-F; Yang W; Yang WY; Yang X; Yang X; Yang Y; Yang Y; Yao H; Yao S; Yao X; Yao Y-G; Yao Y-M; Yasui T; Yazdankhah M; Yen PM; Yi C; Yin X-M; Yin Y; Yin Z; Yin Z; Ying M; Ying Z; Yip CK; Yiu SPT; Yoo YH; Yoshida K; Yoshii SR; Yoshimori T; Yousefi B; Yu B; Yu H; Yu J; Yu J; Yu L; Yu M-L; Yu S-W; Yu VC; Yu WH; Yu Z; Yu Z; Yuan J; Yuan L-Q; Yuan S; Yuan S-SF; Yuan Y; Yuan Z; Yue J; Yue Z; Yun J; Yung RL; Zacks DN; Zaffagnini G; Zambelli VO; Zanella I; Zang QS; Zanivan S; Zappavigna S; Zaragoza P; Zarbalis KS; Zarebkohan A; Zarrouk A; Zeitlin SO; Zeng J; Zeng J-D; Zerovnik E; Zhan L; Zhang B; Zhang DD; Zhang H; Zhang H; Zhang H; Zhang H; Zhang H; Zhang H; Zhang H; Zhang H-L; Zhang J; Zhang J; Zhang J-P; Zhang KYB; Zhang LW; Zhang L; Zhang L; Zhang L; Zhang L; Zhang M; Zhang P; Zhang S; Zhang W; Zhang X; Zhang X-W; Zhang X; Zhang X; Zhang X; Zhang X; Zhang XD; Zhang Y; Zhang Y; Zhang Y; Zhang Y-D; Zhang Y; Zhang Y-Y; Zhang Y; Zhang Z; Zhang Z; Zhang Z; Zhang Z; Zhang Z; Zhang Z; Zhao H; Zhao L; Zhao S; Zhao T; Zhao X-F; Zhao Y; Zhao Y; Zhao Y; Zhao Y; Zheng G; Zheng K; Zheng L; Zheng S; Zheng X-L; Zheng Y; Zheng Z-G; Zhivotovsky B; Zhong Q; Zhou A; Zhou B; Zhou C; Zhou G; Zhou H; Zhou H; Zhou H; Zhou J; Zhou J; Zhou J; Zhou J; Zhou K; Zhou R; Zhou X-J; Zhou Y; Zhou Y; Zhou Y; Zhou Z-Y; Zhou Z; Zhu B; Zhu C; Zhu G-Q; Zhu H; Zhu H; Zhu H; Zhu W; Zhu Y; Zhu Y; Zhuang H; Zhuang X; Zientara-Rytter K; Zimmermann CM; Ziviani E; Zoladek T; Zong W-X; Zorov DB; Zorzano A; Zou W; Zou Z; Zou Z; Zuryn S; Zwerschke W; Brand-Saberi B; Dong XC; Kenchappa CS; Li Z; Lin Y; Oshima S; Rong Y; Sluimer JC; Stallings CL; Tong C-K
Review: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020;533(1):36-49
Brave new world revisited: Focus on nanomedicine
Fadeel B; Alexiou C
Editorial comment: NANOMEDICINE. 2020;15(24):2411-2427
No small matter: a perspective on nanotechnology-enabled solutions to fight COVID-19
Jones GW; Monopoli MP; Campagnolo L; Pietroiusti A; Tran L; Fadeel B
Other: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020;529(4):882-883
In memoriam: Sten Orrenius (1937-2020)
Fadeel B; Zhivotovsky B
Editorial comment: MATTER. 2020;3(1):4
I May Not Care About the Tenure Clock, but Enough Already!
Fadeel B
Letter: NATURE NANOTECHNOLOGY. 2020;15(3):164
Grouping all carbon nanotubes into a single substance category is scientifically unjustified
Fadeel B; Kostarelos K
Review: THERANOSTICS. 2020;10(12):5435-5488
Graphene and other 2D materials: a multidisciplinary analysis to uncover the hidden potential as cancer theranostics
Fusco L; Gazzi A; Peng G; Shin Y; Vranic S; Bedognetti D; Vitale F; Yilmazer A; Feng X; Fadeel B; Casiraghi C; Delogu LG
Editorial comment: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;520(4):674-675
Don't look back in anger: Lessons from cell death research
Fadeel B
Review: CELL DEATH & DISEASE. 2019;10(8):569
Nano-bio interactions: a neutrophil-centric view
Keshavan S; Calligari P; Stella L; Fusco L; Delogu LG; Fadeel B
Letter: NATURE NANOTECHNOLOGY. 2019;14(7):629-635
On the issue of transparency and reproducibility in nanomedicine
Leong HS; Butler KS; Brinker CJ; Azzawi M; Conlan S; Dufes C; Owen A; Rannard S; Scott C; Chen C; Dobrovolskaia MA; Kozlov SV; Prina-Mello A; Schmid R; Wick P; Caputo F; Boisseau P; Crist RM; McNeil SE; Fadeel B; Lang T; Hansen SF; Hartmann NB; Clausen LPW; Skjolding LM; Baun A; Agerstrand M; Gu Z; Lamprou DA; Hoskins C; Huang L; Song W; Cao H; Liu X; Jandt KD; Jiang W; Kim BYS; Wheeler KE; Chetwynd AJ; Lynch I; Moghimi SM; Nel A; Xia T; Weiss PS; Sarmento B; das Neves J; Santos HA; Santos L; Mitragotri S; Little S; Peer D; Amiji MM; Alonso MJ; Petri-Fink A; Balog S; Lee A; Drasler B; Rothen-Rutishauser B; Wilhelm S; Acar H; Harrison RG; Mao C; Mukherjee P; Ramesh R; McNally LR; Busatto S; Wolfram J; Bergese P; Ferrari M; Fang RH; Zhang L; Zheng J; Peng C; Du B; Yu M; Charron DM; Zheng G; Pastore C
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2019;185(1):179-183
HAX-1 overexpression in multiple myeloma is associated with poor survival
Feng X; Kwiecinska A; Rossmann E; Bottai M; Ishikawa T; Patarroyo M; Osterborg A; Porwit A; Zheng C; Fadeel B
Editorial comment: FRONTIERS IN TOXICOLOGY. 2019;1:1
The Right Stuff: On the Future of Nanotoxicology
Fadeel B
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:133
Hide and Seek: Nanomaterial Interactions With the Immune System
Fadeel B
Review: ACS NANO. 2018;12(11):10582-10620
Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment
Fadeel B; Bussy C; Merino S; Vazquez E; Flahaut E; Mouchet F; Evariste L; Gauthier L; Koivisto AJ; Vogel U; Martin C; Delogu LG; Buerki-Thurnherr T; Wick P; Beloin-Saint-Pierre D; Hischier R; Pelin M; Carniel FC; Tretiach M; Cesca F; Benfenati F; Scaini D; Ballerini L; Kostarelos K; Prato M; Bianco A
Review: SEMINARS IN IMMUNOLOGY. 2017;34(C):33-51
Nanoparticles and innate immunity: new perspectives on host defence
Boraschi D; Italiani P; Palomba R; Decuzzi P; Duschl A; Fadeel B; Moghimi SM
Editorial comment: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;482(3):383
Editorial: Special issue on cell death in honor of Sten Orrenius
Fadeel B; Moldeus P
Review: FRONTIERS IN IMMUNOLOGY. 2017;8:673
Graphene and the immune System: A Romance of Many Dimensions
Mukherjee SP; Bottini M; Fadeel B
Editorial comment: GENE THERAPY. 2016;23(7):560-564
Tackling chondrocyte hypertrophy with multifunctional nanoparticles
Bottini M; Magrini A; Fadeel B; Rosato N
Review: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2016;12(2):333-351
Biological interactions of carbon-based nanomaterials: From coronation to degradation
Bhattacharya K; Mukherjee SP; Gallud A; Burkert SC; Bistarelli S; Bellucci S; Bottini M; Star A; Fadeel B
Review: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;468(3):498-503
Keeping it real: The importance of material characterization in nanotoxicology
Fadeel B; Fornara A; Toprak MS; Bhattacharya K
Editorial comment: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;468(3):409-410
Editorial: Brave new world - Focus on nanomedicine
Alexiou C; Fadeel B
Editorial comment: BMJ-BRITISH MEDICAL JOURNAL. 2015;351:h6505
CHRISTMAS 2015: THE PUBLICATION GAME Freewheelin' scientists: citing Bob Dylan in the biomedical literature
Gornitzki C; Larsson A; Fadeel B
Corrigendum: CARBON. 2015;95:766
Lactoperoxidase-mediated degradation of single-walled carbon nanotubes in the presence of pulmonary surfactant (vol 91, pg 506, 2015)
Bhattacharya K; El-Sayed R; Andon FT; Mukherjee SP; Gregory J; Li H; Zhao Y; Seo W; Fornara A; Brandner B; Toprak MS; Leifer K; Star A; Fadeel B
Editorial comment: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;465(1):v-vii
Meeting report: BBRC Symposium on Trends in Biochemistry and Biophysics
Fadeel B; Carafoli E
Editorial comment: NANOMEDICINE. 2015;10(12):1859-1861
Recent nanomedicine articles of outstanding interest
Gallud A; Libalova H; Fadeel B
Editorial comment: NANOMEDICINE. 2015;10(7):1039-1041
Systems biology in nanosafety research
Fadeel B
Other: NANOMEDICINE. 2014;9(1):19-20
Biomimetic camouflage: nanoporous particles cloaked in cellular membranes
Brzicova T; Feliu N; Fadeel B
Other: NANOMEDICINE. 2014;9(1):19
Now you see it, now you don't: serum proteins prevent specific targeting of nanoparticles
Brzicova T; Feliu N; Fadeel B
Other: NANOMEDICINE. 2014;9(1):18-19
Flying under the radar: functionalization of nanoparticles with 'marker of self' peptides
Brzicova T; Feliu N; Fadeel B
Other: NANOMEDICINE. 2014;9(1):18
Of mice and men: global immune status determines nanoparticle clearance
Brzicova T; Feliu N; Fadeel B
Other: NANOMEDICINE. 2014;9(1):17-20
Ins and outs of lipid nanoparticle-mediated siRNA delivery
Brzicova T; Feliu N; Fadeel B
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2013;274(6):578-580
Nanosafety: towards safer design of nanomedicines
Fadeel B
Review: ADVANCED DRUG DELIVERY REVIEWS. 2013;65(15):2087-2097
Mechanisms of carbon nanotube-induced toxicity: Focus on pulmonary inflammation
Bhattacharya K; Andon FT; El-Sayed R; Fadeel B
Editorial comment: TOXICOLOGY. 2013;313(1):1-2
Nanotoxicology
Fadeel B; Alenius H; Savolainen K
Review: SMALL. 2013;9(9-10):1557-1572
Interactions of Engineered Nanoparticles with Organs Protected by Internal Biological Barriers
Pietroiusti A; Campagnolo L; Fadeel B
Letter: SCIENCE. 2013;340(6132):548-549
Geoengineering: Perilous Particles
Fadeel B; Karlsson HL; Bhattacharya K
Review: ACCOUNTS OF CHEMICAL RESEARCH. 2013;46(3):733-742
Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials
Andon FT; Fadeel B
Review: WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY. 2013;5(2):111-129
Bridge over troubled waters: understanding the synthetic and biological identities of engineered nanomaterials
Fadeel B; Feliu N; Vogt C; Abdelmonem AM; Parak WJ
Letter: NATURE NANOTECHNOLOGY. 2013;8(2):71
Broaden the discussion
Fadeel B; Savolainen K
Other: NANOMEDICINE. 2012;7(9):1295
DNA origami: self-assembled nucleic acid nanoparticles for siRNA delivery.
Andón FT; Pazinatto DB; Fadeel B
Other: NANOMEDICINE. 2012;7(9):1294-1295
The importance of size: nanomedicine for delivery of anticancer drugs in solid tumors.
Andón FT; Pazinatto DB; Fadeel B
Other: NANOMEDICINE. 2012;7(9):1294
Perinatal nanomedicine: dendrimer-based therapy for neuroinflammatory disorders.
Andón FT; Pazinatto DB; Fadeel B
Editorial comment: NANOMEDICINE. 2012;7(9):1293
Towards the clinic: intelligent design of nanomedicines for cancer treatment.
Andón FT; Pazinatto DB; Fadeel B
Other: NANOMEDICINE. 2012;7(9):1295-1296
Towards the clinic: intelligent design of nanomedicines for cancer treatment
Andon FT; Pazinatto DB; Fadeel B
Review: JOURNAL OF CONTROLLED RELEASE. 2012;161(2):403-408
Safety assessment of nanomaterials: Implications for nanomedicine
Nystrom AM; Fadeel B
Review: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2012;261(2):121-133
Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress
Shvedova AA; Pietroiusti A; Fadeel B; Kagan VE
Letter: LEUKEMIA. 2011;25(5):868-872
HAX-1 expression in human B lymphoma
Kwiecinska A; Ottosson-Wadlund A; Ceder R; Grafstrom RC; Bjorck E; Nordenskjold M; Porwit A; Fadeel B
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2011;1810(3):361-373
Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation
Kunzmann A; Andersson B; Thurnherr T; Krug H; Scheynius A; Fadeel B
Editorial comment: JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2010;52(9):943-946
Fantastic voyage and opportunities of engineered nanomaterials: what are the potential risks of occupational exposures?
Kagan VE; Shi J; Feng W; Shvedova AA; Fadeel B
Review: ADVANCED DRUG DELIVERY REVIEWS. 2010;62(3):362-374
Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications
Fadeel B; Garcia-Bennett AE
Review: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. 2010;50:63-88
Close Encounters of the Small Kind: Adverse Effects of Man-Made Materials Interfacing with the Nano-Cosmos of Biological Systems
Shvedova AA; Kagan VE; Fadeel B
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2010;267(1):2-8
Nanomedicine: reshaping clinical practice
Fadeel B; Kasemo B; Malmsten M; Stromme M
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2009;147(4):587-590
Double de novo mutations of ELANE (ELA2) in a patient with severe congenital neutropenia requiring high-dose G-CSF therapy
Lunden L; Boxhammer S; Carlsson G; Ellstrom K-G; Nordenskjold M; Lagerstedt-Robinson K; Fadeel B
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1790(10):1139-1148
HAX-1: A multifunctional protein with emerging roles in human disease
Fadeel B; Grzybowska E
Review: CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2009;44(5):264-277
The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease
Fadeel B; Xue D
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2009;146(2):218-220
Multiple inherited sequence variations in two disease-causing genes in familial haemophagocytic lymphohistiocytosis
Rudd E; Meeths M; Uysal Z; Nordenskjoeld M; Henter J-I; Fadeel B
Editorial comment: BLOOD. 2009;113(25):6270-6271
Babies born without safety NET
Fadeel B
Letter: FASEB JOURNAL. 2009;23(5):1283
"But many that are first shall be last; and the last shall be first"
Fadeel B
Letter: LEUKEMIA. 2009;23(3):622-625
Survivin expression in the bone marrow of patients with severe congenital neutropenia
Carlsson G; Boxhammer S; Garwicz D; Henter JI; Palmblad J; Nordenskjold M; Porwit A; Fadeel B
Review: PHARMACOLOGY & THERAPEUTICS. 2009;121(2):192-204
Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus?
Shvedova AA; Kisin ER; Porter D; Schulte P; Kagan VE; Fadeel B; Castranova V
Letter: LEUKEMIA. 2008;22(4):883-884
Proteasome inhibition therapies in childhood cancer
Zaman F; Fadeel B; Savendahl L
Review: CELL DEATH AND DIFFERENTIATION. 2008;15(3):443-452
Big wheel keeps on turning: apoptosome regulation and its role in chemoresistance
Fadeel B; Ottosson A; Pervaiz S
Review: ACTA PAEDIATRICA. 2007;96(6):813-819
Kostmann syndrome or infantile genetic agranulocytosis, part two:: understanding the underlying genetic defects in severe congenital neutropenia
Carlsson G; Melin M; Dahl N; Ramme KG; Nordenskjold M; Palmblad J; Henter J-I; Fadeel B
Letter: CELL DEATH AND DIFFERENTIATION. 2007;14(5):1063-1065
Bridge over troubled water:: milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells
Witasp E; Uthaisang W; Elenstrom-Magnusson C; Hanayama R; Tanaka M; Nagata S; Orrenius S; Fadeel B
Published conference paper: NANOTOXICOLOGY. 2007;1(2):73-84
There's plenty of room at the forum: Potential risks and safety assessment of engineered nanomaterials
Fadeel B; Kagan V; Krug H; Shvedova A; Svartengren M; Tran L; Wiklund L
Review: ACTA PAEDIATRICA. 2006;95(12):1526-1532
Kostmann syndrome or infantile genetic agranulocytosis, part one:: Celebrating 50 years of clinical and basic research on severe congenital neutropenia
Carlsson G; Andersson M; Putsep K; Garwicz D; Nordenskjold M; Henter J-I; Palmblad J; Fadeel B
Review: JOURNAL OF INTERNAL MEDICINE. 2006;260(1):1-10
A journey of hope:: lessons learned from studies on rare diseases and orphan drugs
Wästfelt M; Fadeel B; Henter J-I
Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2006;1757(5-6):648-659
Apoptotic interactions of cyctochrome c:: Redox flirting with anionic phospholipids within and outside of mitochondria
Bayir H; Fadeel B; Palladino MJ; Witasp E; Kurnikov IV; Tyurina YY; Tyurin VA; Amoscato AA; Jiang J; Kochanek PM; DeKosky ST; Greenberger JS; Shvedova AA; Kagan VE
Review: JOURNAL OF INTERNAL MEDICINE. 2005;258(6):479-517
Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease
Fadeel B; Orrenius S
Letter: LEUKEMIA. 2005;19(1):159-161
Raji revisited:: cytogenetics of the original Burkitt's lymphoma cell line
Karpova MB; Schoumans J; Ernberg I; Henter JI; Nordenskjöld M; Fadeel B
Letter: BLOOD. 2004;104(5):1582-1583
Phosphatidylserine externalization in cardiolipin-deficient cells
Fadeel B; Karpova MB; Enoksson M; Orrenius S
Letter: CELL DEATH AND DIFFERENTIATION. 2004;11(8):943-945
Milk fat globule epidermal growth factor 8 (MFG-E8) binds to oxidized phosphatidylserine: implications for macrophage clearance of apoptotic cells
Borisenko GG; Iverson SL; Ahlberg S; Kagan VE; Fadeel B
Review: ANTIOXIDANTS & REDOX SIGNALING. 2004;6(2):269-275
Plasma membrane alterations during apoptosis: Role in corpse clearance
Fadeel B
Other: BLOOD. 2004;103(2):389
Retraction. Neutrophil elastase mutations in severe congenital neutropenia patients of the original Kostmann family.
Aprikyan AA; Carlsson G; Stein S; Oganesian A; Fadeel B; Dale DC; Palmblad J; Henter J-I
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2003;60(12):2575-2585
Programmed cell clearance
Fadeel B
Letter: TRENDS IN IMMUNOLOGY. 2003;24(8):409-410
Langerhans-cell histiocytosis: neoplasia or unbridled inflammation?
Fadeel B; Henter JI
Review: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2003;285(1):L1-17
Appetizing rancidity of apoptotic cells for macrophages: oxidation, externalization, and recognition of phosphatidylserine
Kagan VE; Borisenko GG; Serinkan BF; Tyurina YY; Tyurin VA; Jiang J; Liu SX; Shvedova AA; Fabisiak JP; Uthaisang W; Fadeel B
Review: REDOX REPORT. 2003;8(3):143-150
Apoptosis and macrophage clearance of neutrophils: regulation by reactive oxygen species
Fadeel B; Kagan VE
Other: CELL DEATH AND DIFFERENTIATION. 2002;9(4):468-475
'Centennial' Nobel Conference on apoptosis and human disease.
Robertson JD; Fadeel B; Zhivotovsky B; Orrenius S
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2001;345(21):1577-1578
Successful treatment of Langerhans'-cell histiocytosis with etanercept
Henter JI; Karlén J; Calming U; Bernstrand C; Andersson U; Fadeel B
Review: LEUKEMIA & LYMPHOMA. 2001;42(1-2):13-20
Familial hemophagocytic lymphohistiocytosis: Too little cell death can seriously damage your health
Fadeel B; Orrenius S; Henter JI
Review: LEUKEMIA. 2000;14(8):1514-1525
The most unkindest cut of all*: on the multiple roles of mammalian caspases
Fadeel B; Orrenius S; Zhivotovsky B
Review: LAKARTIDNINGEN. 2000;97(12):1405-1408
[Familial hemophagocytic lymphohistiocytosis: diagnosis, treatment and pathophysiological mechanisms].
Henter JI; Samuelsson A; Ericson K; Nilsson-Ardnor S; Elinder G; Fadeel B
Review: LAKARTIDNINGEN. 2000;97(12):1395-1402
[Apoptosis required for maintenance of homeostasis: familial hemophagocytic lymphohistiocytosis caused by too little cell death].
Fadeel B; Henter JI; Orrenius S
Review: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;266(3):699-717
Apoptosis in human disease: A new skin for the old ceremony?
Fadeel B; Orrenius S; Zhivotovsky B
Review: FASEB JOURNAL. 1999;13(13):1647-1657
All along the watchtower: on the regulation of apoptosis regulators
Fadeel B; Zhivotovsky B; Orrenius S
Thesis / dissertation: 1999
Mechanisms and mediators of apoptosis : with special reference to hematological disorders
Fadeel, Bengt
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1998;854:328-335
Redox regulation of the caspases during apoptosis
Hampton MB; Fadeel B; Orrenius S
Letter: BLOOD. 1996;88(12):4727-4730
Elevated serum levels of soluble Fas/APO-1 in human immunodeficiency virus-infected individuals
Fadeel B; Samuelsson A; Hachiya T; Brostrom C; Chiodi F
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Forskningsbidrag

BACTERADIX: Advanced Nanomaterials to Target Genomic and Z-DNA for Bacterial Biofilm Eradication
European Commission
1 December 2024 - 30 November 2028
PERSEUS: Multi-Functional 2D Nanocrystal-Based Oncotherapy triggered by Computed Tomography
European Commission
1 March 2023 - 28 February 2027
Beyond Graphene: Exploring Biological Interactions of Transition Metal Dichalcogenides and MXenes
Swedish Research Council
1 January 2022 - 31 December 2025
MISTRA Environmental Nanosafety
MISTRA - Stiftelsen för miljöstrategisk forskning
1 January 2014 - 30 September 2023
Graphene Flagship
European Commission
1 October 2013 - 30 September 2023

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Professor, Institutet för miljömedicin, Karolinska Institutet, 2010-

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Docent, Toxikologi, Karolinska Institutet, 2004
Leg. Läkare, Karolinska University Hospital, 2001
MEDICINE DOKTORSEXAMEN, Institutet för miljömedicin, Karolinska Institutet, 1999
Läkarexamen, Karolinska Institutet, 1997

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