Åsa Wheelock

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Åsa M. Wheelock
Docent i experimentell lungmedicin
Ph.D. i toxikologi och farmakologi
Bitr. enhetschef, Enheten för lungmedicin

Forskningsbeskrivning

Läs om vår forskargrupp på engelska här [1]
[1] https://staff.ki.se/people/asa-wheelock

Artiklar

Article: RESPIRATORY RESEARCH. 2024;25(1):86
Large airway T cells in adults with former bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Li C; Merikallio H; Kaarteenaho R; Reinke NS; Wheelock CE; Melen E; Anders L; Wheelock AM; Rassidakis G; Ortiz-Villalon C; Skold MC
Article: BRIEFINGS IN BIOINFORMATICS. 2023;25(1):bbad501
Consensus clustering with missing labels (ccml): a consensus clustering tool for multi-omics integrative prediction in cohorts with unequal sample coverage
Li C-X; Chen H; Zounemat-Kermani N; Adcock IM; Skold CM; Zhou M; Wheelock AM
Article: ERJ OPEN RESEARCH. 2023;9(5):00269-2023
Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids
Yasinska V; Gomez C; Kolmert J; Ericsson M; Pohanka A; James A; Andersson LI; Sparreman-Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Kermani NZ; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth PH; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Dahlen B; Maitland-van der Zee A-H; Sterk PJ; Djukanovic R; Adcock IM; Chung KF; Wheelock CE; Dahlen S-E; Jonsson EW
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(17):13546
Mucins 3A and 3B Are Expressed in the Epithelium of Human Large Airway.
Merikallio H; Pincikova T; Kotortsi I; Karimi R; Li C-X; Forsslund H; Mikko M; Nyrén S; Lappi-Blanco E; Wheelock ÅM; Kaarteenaho R; Sköld MC
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;208(2):142-154
Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk
Abdel-Aziz MI; Thorsen J; Hashimoto S; Vijverberg SJH; Neerincx AH; Brinkman P; van Aalderen W; Stokholm J; Rasmussen MA; Roggenbuck-Wedemeyer M; Vissing NH; Mortensen MS; Brejnrod AD; Fleming LJ; Murray CS; Fowler SJ; Frey U; Bush A; Singer F; Hedlin G; Nordlund B; Shaw DE; Chung KF; Adcock IM; Djukanovic R; Auffray C; Bansal AT; Sousa AR; Wagers SS; Chawes BL; Bonnelykke K; Sorensen SJ; Kraneveld AD; Sterk PJ; Roberts G; Bisgaard H; Maitland-van der Zee AH
Article: FRONTIERS IN PUBLIC HEALTH. 2023;11:1052946
Monkeypox outbreaks in the context of the COVID-19 pandemic: Network and clustering analyses of global risks and modified SEIR prediction of epidemic trends
Gao J; Zhou C; Liang H; Jiao R; Wheelock AM; Jiao K; Ma J; Zhang C; Guo Y; Luo S; Liang W; Xu L
Article: FRONTIERS IN PUBLIC HEALTH. 2023;11:1150095
The role of booster vaccination in decreasing COVID-19 age-adjusted case fatality rate: Evidence from 32 countries
Zhou C; Wheelock AM; Zhang C; Ma J; Dong K; Pan J; Li Z; Liang W; Gao J; Xu L
Article: THE LANCET RESPIRATORY MEDICINE. 2023;11(1):55-64
Predictors and associations of the persistent airflow limitation phenotype in asthma: a post-hoc analysis of the ATLANTIS study
Kole TM; Vanden Berghe E; Kraft M; Vonk JM; Nawijn MC; Siddiqui S; Sun K; Fabbri LM; Rabe KF; Chung KF; Nicolini G; Papi A; Brightling C; Singh D; van der Molen T; Dahlen S-E; Agusti A; Faner R; Wedzicha JA; Donaldson GC; Adcock IM; Lahousse L; Kerstjens HAM; van den Berge M
Article: ANALYTICAL CHEMISTRY. 2022;94(42):14618-14626
Development of a Chiral Supercritical Fluid Chromatography-Tandem Mass Spectrometry and Reversed-Phase Liquid Chromatography-Tandem Mass Spectrometry Platform for the Quantitative Metabolic Profiling of Octadecanoid Oxylipins
Quaranta A; Zohrer B; Revol-Cavalier J; Benkestock K; Balas L; Oger C; Keyes GS; Wheelock AM; Durand T; Galano J-M; Ramsden CE; Hamberg M; Wheelock CE
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;60(3):2102531
Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia
Um-Bergstrom P; Pourbazargan M; Brundin B; Strom M; Ezerskyte M; Gao J; Brostrom EB; Melen E; Wheelock AM; Linden A; Skold CM
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;59(6):2101733
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study
Reinke SN; Naz S; Chaleckis R; Gallart-Ayala H; Kolmert J; Kermani NZ; Tiotiu A; Broadhurst DI; Lundqvist A; Olsson H; Strom M; Wheelock AM; Gomez C; Ericsson M; Sousa AR; Riley JH; Bates S; Scholfield J; Loza M; Baribaud F; Bakke PS; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth P; Horvath I; Krug N; Montuschi P; Behndig A; Singer F; Musial J; Shaw DE; Dahlen B; Hu S; Lasky-Su J; Sterk PJ; Chung KF; Djukanovic R; Dahlen S-E; Adcock IM; Wheelock CE
Article: BRIEFINGS IN BIOINFORMATICS. 2022;23(1):bbab485
Multiomics integration-based molecular characterizations of COVID-19
Li C-X; Gao J; Zhang Z; Chen L; Li X; Zhou M; Wheelock AM
Article: FRONTIERS IN GENETICS. 2022;13:1010048
miRNA-mRNA-protein dysregulated network in COPD in women
Li CX; Gao J; Skold CM; Wheelock AM
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(24):13421
Distal Lung Microenvironment Triggers Release of Mediators Recognized as Potential Systemic Biomarkers for Idiopathic Pulmonary Fibrosis
Kalafatis D; Loefdahl A; Naesman P; Dellgren G; Wheelock AM; Elowsson Rendin L; Skoeld M; Westergren-Thorsson G
Article: ANALYTICAL CHEMISTRY. 2021;93(12):5248-5258
High-Precision Automated Workflow for Urinary Untargeted Metabolomic Epidemiology
Meister I; Zhang P; Sinha A; Skold CM; Wheelock AM; Izumi T; Chaleckis R; Wheelock CE
Article: RESPIRATORY RESEARCH. 2021;22(1):40
Baseline characteristics and survival of patients of idiopathic pulmonary fibrosis: a longitudinal analysis of the Swedish IPF Registry
Gao J; Kalafatis D; Carlson L; Pesonen IHA; Li C-X; Wheelock A; Magnusson JM; Skold CM
Article: JCI INSIGHT. 2021;6(2):134218
MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease
Nouws J; Wan F; Finnemore E; Roque W; Kim S-J; Bazan I; Li C-X; Skold CM; Dai Q; Yan X; Chioccioli M; Neumeister V; Britto CJ; Sweasy J; Bindra R; Wheelock AM; Gomez JL; Kaminski N; Lee PJ; Sauler M
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2021;203(1):37-53
Urinary Leukotriene E₄ and Prostaglandin D₂ Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation A Clinical Observational Study
Kolmert J; Gomez C; Balgoma D; Sjodin M; Bood J; Konradsen JR; Ericsson M; Thorngren J-O; James A; Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Pandis I; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth P; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Holweg CTJ; Wheelock AM; Dahlen B; Nordlund B; Alving K; Hedlin G; Chung KF; Adcock IM; Sterk PJ; Djukanovic R; Dahlen S-E; Wheelock CE
Article: ENVIRONMENT INTERNATIONAL. 2021;146:106248
Integration of gene expression and DNA methylation identifies epigenetically controlled modules related to PM2.5 exposure.
Merid SK; Bustamante M; Standl M; Sunyer J; Heinrich J; Lemonnier N; Aguilar D; Antó JM; Bousquet J; Santa-Marina L; Lertxundi A; Bergström A; Kull I; Wheelock ÅM; Koppelman GH; Melén E; Gruzieva O
Article: RESPIRATORY RESEARCH. 2020;21(1):239
Smoking-associated increase in mucins 1 and 4 in human airways
Merikallio H; Kaarteenaho R; Linden S; Padra M; Karimi R; Li C-X; Lappi-Blanco E; Wheelock AM; Skold MC
Journal article: ENVIRONMENTAL EPIDEMIOLOGY. 2019;3(Supplement 1):269
Integration of whole blood genome-wide DNA methylation and gene expression identifies epigenetically controlled modules in relation to NO2 air pollution exposure
S M; M B; M S; J S; J H; C A; Å W; G K; E M; O G
Article: METABOLITES. 2019;9(10):E212-212
Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD
Naz S; Bhat M; Stahl S; Forsslund H; Skold CM; Wheelock AM; Wheelock CE
Article: RESPIRATORY RESEARCH. 2019;20(1):102
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson MJ; Nyren S; Gao J; Lilja G; Linden A; Wheelock AM; Melen E; Skold CM
Article: RESPIRATORY RESEARCH. 2018;19(1):236
Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study
Sjodin MOD; Checa A; Yang M; Dahlen S-E; Wheelock AM; Eklund A; Grunewald J; Wheelock CE
Article: JOURNAL OF LIPID RESEARCH. 2018;59(10):2025-2033
An LC-MS/MS workflow to characterize 16 regio- and stereoisomeric trihydroxyoctadecenoic acids
Fuchs D; Hamberg M; Skold CM; Wheelock AM; Wheelock CE
Article: CLINICAL SCIENCE. 2018;132(9):959-983
The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers
Che KF; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold CM; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2018;51(5):1701930
Integration of multi-omics datasets enables molecular classification of COPD
Li C-X; Wheelock CE; Skold CM; Wheelock AM
Article: RESPIRATORY RESEARCH. 2018;19(1):39
Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype
Yang M; Kohler M; Heyder T; Forsslund H; Garberg HK; Karimi R; Grunewald J; Berven FS; Nyren S; Skold CM; Wheelock AM
Article: RESPIRATORY RESEARCH. 2018;19(1):40
Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD
Yang M; Kohler M; Heyder T; Forsslund H; Garberg HK; Karimi R; Grunewald J; Berven FS; Skold CM; Wheelock AM
Article: JOURNAL OF EXTRACELLULAR VESICLES. 2018;7(1):1535750
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Thery C; Witwer KW; Aikawa E; Jose Alcaraz M; Anderson JD; Andriantsitohaina R; Antoniou A; Arab T; Archer F; Atkin-Smith GK; Ayre DC; Bach J-M; Bachurski D; Baharvand H; Balaj L; Baldacchino S; Bauer NN; Baxter AA; Bebawy M; Beckham C; Zavec AB; Benmoussa A; Berardi AC; Bergese P; Bielska E; Blenkiron C; Bobis-Wozowicz S; Boilard E; Boireau W; Bongiovanni A; Borras FE; Bosch S; Boulanger CM; Breakefield X; Breglio AM; Brennan MA; Brigstock DR; Brisson A; Broekman MLD; Bromberg JF; Bryl-Gorecka P; Buch S; Buck AH; Burger D; Busatto S; Buschmann D; Bussolati B; Buzas EI; Byrd JB; Camussi G; Carter DRF; Caruso S; Chamley LW; Chang Y-T; Chen C; Chen S; Cheng L; Chin AR; Clayton A; Clerici SP; Cocks A; Cocucci E; Coffey RJ; Cordeiro-da-Silva A; Couch Y; Coumans FAW; Coyle B; Crescitelli R; Criado MF; D'Souza-Schorey C; Das S; Chaudhuri AD; de Candia P; De Santana Junior EF; De Wever O; del Portillo HA; Demaret T; Deville S; Devitt A; Dhondt B; Di Vizio D; Dieterich LC; Dolo V; Dominguez Rubio AP; Dominici M; Dourado MR; Driedonks TAP; Duarte FV; Duncan HM; Eichenberger RM; Ekstrom K; Andaloussi SEL; Elie-Caille C; Erdbrugger U; Falcon-Perez JM; Fatima F; Fish JE; Flores-Bellver M; Forsonits A; Frelet-Barrand A; Fricke F; Fuhrmann G; Gabrielsson S; Gamez-Valero A; Gardiner C; Gaertner K; Gaudin R; Gho YS; Giebel B; Gilbert C; Gimona M; Giusti I; Goberdhan DCI; Goergens A; Gorski SM; Greening DW; Gross JC; Gualerzi A; Gupta GN; Gustafson D; Handberg A; Haraszti RA; Harrison P; Hegyesi H; Hendrix A; Hill AF; Hochberg FH; Hoffmann KF; Holder B; Holthofer H; Hosseinkhani B; Hu G; Huang Y; Huber V; Hunt S; Ibrahim AG-E; Ikezu T; Inal JM; Isin M; Ivanova A; Jackson HK; Jacobsen S; Jay SM; Jayachandran M; Jenster G; Jiang L; Johnson SM; Jones JC; Jong A; Jovanovic-Talisman T; Jung S; Kalluri R; Kano S-I; Kaur S; Kawamura Y; Keller ET; Khamari D; Khomyakova E; Khvorova A; Kierulf P; Kim KP; Kislinger T; Klingeborn M; Klinke DJII; Kornek M; Kosanovic MM; Kovacs AF; Kraemer-Albers E-M; Krasemann S; Krause M; Kurochkin IV; Kusuma GD; Kuypers S; Laitinen S; Langevin SM; Languino LR; Lannigan J; Lasser C; Laurent LC; Lavieu G; Lazaro-Ibanez E; Le Lay S; Lee M-S; Lee YXF; Lemos DS; Lenassi M; Leszczynska A; Li ITS; Liao K; Libregts SF; Ligeti E; Lim R; Lim SK; Line A; Linnemannstoens K; Llorente A; Lombard CA; Lorenowicz MJ; Lorincz AM; Lotvall J; Lovett J; Lowry MC; Loyer X; Lu Q; Lukomska B; Lunavat TR; Maas SLN; Malhi H; Marcilla A; Mariani J; Mariscal J; Martens-Uzunova ES; Martin-Jaular L; Martinez MC; Martins VR; Mathieu M; Mathivanan S; Maugeri M; McGinnis LK; McVey MJ; Meckes DGJ; Meehan KL; Mertens I; Minciacchi VR; Moller A; Jorgensen MM; Morales-Kastresana A; Morhayim J; Mullier F; Muraca M; Musante L; Mussack V; Muth DC; Myburgh KH; Najrana T; Nawaz M; Nazarenko I; Nejsum P; Neri C; Neri T; Nieuwland R; Nimrichter L; Nolan JP; Nolte-'t Hoen ENM; Noren Hooten N; O'Driscoll L; O'Grady T; O'Loghlen A; Ochiya T; Olivier M; Ortiz A; Ortiz LA; Osteikoetxea X; Ostegaard O; Ostrowski M; Park J; Pegtel DM; Peinado H; Perut F; Pfaffl MW; Phinney DG; Pieters BCH; Pink RC; Pisetsky DS; von Strandmann EP; Polakovicova I; Poon IKH; Powell BH; Prada I; Pulliam L; Quesenberry P; Radeghieri A; Raffai RL; Raimondo S; Rak J; Ramirez MI; Raposo G; Rayyan MS; Regev-Rudzki N; Ricklefs FL; Robbins PD; Roberts DD; Rodrigues SC; Rohde E; Rome S; Rouschop KMA; Rughetti A; Russell AE; Saa P; Sahoo S; Salas-Huenuleo E; Sanchez C; Saugstad JA; Saul MJ; Schiffelers RM; Schneider R; Schoyen TH; Scott A; Shahaj E; Sharma S; Shatnyeva O; Shekari F; Shelke GV; Shetty AK; Shiba K; Siljander PR-M; Silva AM; Skowronek A; Snyder OLII; Soares RP; Sodar BW; Soekmadji C; Sotillo J; Stahl PD; Stoorvogel W; Stott SL; Strasser EF; Swift S; Tahara H; Tewari M; Timms K; Tiwari S; Tixeira R; Tkach M; Toh WS; Tomasini R; Torrecilhas AC; Pablo Tosar J; Toxavidis V; Urbanelli L; Vader P; van Balkom BWM; van der Grein SG; Van Deun J; van Herwijnen MJC; Van Keuren-Jensen K; van Niel G; van Royen ME; van Wijnen AJ; Helena Vasconcelos M; Vechetti IJJ; Veit TD; Vella LJ; Velot E; Verweij FJ; Vestad B; Vinas JL; Visnovitz T; Vukman KV; Wahlgren J; Watson DC; Wauben MHM; Weaver A; Webber JP; Weber V; Wehman AM; Weiss DJ; Welsh JA; Wendt S; Wheelock AM; Wiener Z; Witte L; Wolfram J; Xagorari A; Xander P; Xu J; Yan X; Yanez-Mo M; Yin H; Yuana Y; Zappulli V; Zarubova J; Zekas V; Zhang J-Y; Zhao Z; Zheng L; Zheutlin AR; Zickler AM; Zimmermann P; Zivkovic AM; Zocco D; Zuba-Surma EK
Article: MOLECULAR MEDICINE. 2017;23:247-257
Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
Che KF; Kaarteenaho R; Lappi-Blanco E; Levanen B; Sun J; Wheelock A; Palmberg L; Skold CM; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2017;49(6):1602322
Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD
Naz S; Kolmert J; Yang M; Reinke SN; Kamleh MA; Snowden S; Heyder T; Levanen B; Erle DJ; Skold CM; Wheelock AM; Wheelock CE
Article: EUROPEAN RESPIRATORY JOURNAL. 2017;49(1):1600345
Differences in regional air trapping in current smokers with normal spirometry
Karimi R; Tornling G; Forsslund H; Mikko M; Wheelock AM; Nyren S; Skold CM
Article: INTERNATIONAL JOURNAL OF COPD. 2017;12:35-48
Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes
Forsslund H; Yang M; Mikko M; Karimi R; Nyren S; Engvall B; Grunewald J; Merikallio H; Kaarteenaho R; Wahlstrom J; Wheelock AM; Skold CM
Article: MOLECULAR & CELLULAR PROTEOMICS. 2016;15(9):3017-3029
Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples
Heyder T; Kohler M; Tarasova NK; Haag S; Rutishauser D; Rivera NV; Sandin C; Mia S; Malmstrom V; Wheelock AM; Wahlstrom J; Holmdahl R; Eklund A; Zubarev RA; Grunewald J; Ytterberg AJ
Article: EUROPEAN RESPIRATORY JOURNAL. 2016;47(6):1645-1656
Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD
Balgoma D; Yang M; Sjodin M; Snowden S; Karimi R; Levanen B; Merikallio H; Kaarteenaho R; Palmberg L; Larsson K; Erle DJ; Dahlen S-E; Dahlen B; Skold CM; Wheelock AM; Wheelock CE
Article: SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2016;33(1):17-28
ALTERATIONS IN THE MEMBRANE-ASSOCIATED PROTEOME FRACTION OF ALVEOLAR MACROPHAGES IN SARCOIDOSIS
Kjellin H; Silva E; Branca RM; Eklund A; Jakobsson P-J; Grunewald J; Lehtio J; Wheelock AM
Article: ANALYTICAL CHEMISTRY. 2016;88(6):3067-3074
Use of Time-Resolved Fluorescence To Improve Sensitivity and Dynamic Range of Gel-Based Proteomics
Sandberg A; Buschmann V; Kapusta P; Erdmann R; Wheelock AM
Journal article: EUPA OPEN PROTEOMICS. 2015;9:77
Improving productivity and quality in Biobanking: The need for synergy between industry, academia, and the public sector
Wheelock Å
Article: JOURNAL OF PROTEOMICS. 2015;127(Pt B):414-416
The EuPA Biobank Initiative: Meeting the future challenges of biobanking in proteomics & systems medicine.
Wheelock ÅM; Paulson L; Litton J-E; EuPA Biobank Initiative Group
Article: CHEST. 2014;145(4):711-722
Distribution of T-Cell Subsets in BAL Fluid of Patients With Mild to Moderate COPD Depends on Current Smoking Status and Not Airway Obstruction
Forsslund H; Mikko M; Karimi R; Grunewald J; Wheelock AM; Wahlstrom J; Skold CM
Article: RESPIRATORY RESEARCH. 2014;15(1):23
Lung density on high resolution computer tomography (HRCT) reflects degree of inflammation in smokers
Karimi R; Tornling G; Forsslund H; Mikko M; Wheelock AM; Nyren S; Skold CM
Journal article: RESPIRATORY MEDICINE. 2013;107(11):s5-s6
Assessment of local inflammation in the lungs of smokers by HRCT
Karimi R; Nyrén S; Forsslund H; Wheelock Å; Tornling G; Sköld M
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;132(2):328-35.e5
The chitinase-like protein YKL-40: A possible biomarker of inflammation and airway remodeling in severe pediatric asthma
Konradsen JR; James A; Nordlund B; Reinius LE; Soderhall C; Melen E; Wheelock A; Carlsen KCL; Lidegran M; Verhoek M; Boot RG; Dahlen B; Dahlen SE; Hedlin G
Article: EUROPEAN RESPIRATORY JOURNAL. 2013;41(6):1331-1339
Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis
Silva E; Souchelnytskyi S; Kasuga K; Eklund A; Grunewald J; Wheelock AM
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;131(3):894-903
Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients
Levanen B; Bhakta NR; Paredes PT; Barbeau R; Hiltbrunner S; Pollack JL; Skold CM; Svartengren M; Grunewald J; Gabrielsson S; Eklund A; Larsson B-M; Woodruff PG; Erle DJ; Wheelock AM
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;131(3):743-751
Gender differences in the bronchoalveolar lavage cell proteome of patients with chronic obstructive pulmonary disease
Kohler M; Sandberg A; Kjellqvist S; Thomas A; Karimi R; Nyren S; Eklund A; Thevis M; Skold CM; Wheelock AM
Article: IMMUNOBIOLOGY. 2013;218(2):225-231
Increased intraepithelial (CD103+) CD8+T cells in the airways of smokers with and without chronic obstructive pulmonary disease
Mikko M; Forsslund H; Cui L; Grunewald J; Wheelock AM; Wahlstrom J; Skold CM
Article: ANALYTICAL CHEMISTRY. 2012;84(16):7064-7071
Building Multivariate Systems Biology Models
Kirwan GM; Johansson E; Kleemann R; Verheij ER; Wheelock AM; Goto S; Trygg J; Wheelock CE
Article: BMC MEDICAL GENOMICS. 2012;5:27
Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics
Diez D; Goto S; Fahy JV; Erle DJ; Woodruff PG; Wheelock AM; Wheelock CE
Article: PLOS ONE. 2012;7(3):e33780
Allergic Asthmatics Show Divergent Lipid Mediator Profiles from Healthy Controls Both at Baseline and following Birch Pollen Provocation
Lundstrom SL; Yang J; Kallberg HJ; Thunberg S; Gafvelin G; Haeggstrom JZ; Gronneberg R; Grunewald J; van Hage M; Hammock BD; Eklund A; Wheelock AM; Wheelock CE
Article: RESPIRATORY MEDICINE. 2011;105(2):282-291
Increased pulmonary Wnt (wingless/integrated)-signaling in patients with sarcoidosis
Levanen B; Wheelock AM; Eklund A; Grunewald J; Nord M
Article: PLOS ONE. 2011;6(8):e23864
Asthmatics Exhibit Altered Oxylipin Profiles Compared to Healthy Individuals after Subway Air Exposure
Lundstrom SL; Levanen B; Nording M; Klepczynska-Nystrom A; Skold M; Haeggstrom JZ; Grunewald J; Svartengren M; Hammock BD; Larsson B-M; Eklund A; Wheelock AM; Wheelock CE
Article: PLOS ONE. 2011;6(12):e28864
Assessing Recent Smoking Status by Measuring Exhaled Carbon Monoxide Levels
Sandberg A; Skold CM; Grunewald J; Eklund A; Wheelock AM
Article: JOURNAL OF PROTEOME RESEARCH. 2010;9(3):1522-1532
In the Eye of the Beholder: Does the Master See the SameSpots as the Novice?
Silva E; O'Gorman M; Becker S; Auer G; Eklund A; Grunewald J; Wheelock AM
Article: METHODS IN MOLECULAR BIOLOGY. 2009;519:113-129
Troubleshooting image analysis in 2DE.
Levänen B; Wheelock AM
Article: METHODS IN MOLECULAR BIOLOGY. 2009;579:161-187
HPLC/MS/MS-based approaches for detection and quantification of eicosanoids.
Lundström SL; D'Alexandri FL; Nithipatikom K; Haeggström JZ; Wheelock AM; Wheelock CE
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2008;38(3):300-309
Long-term ozone exposure attenuates 1-nitronaphthalene-induced cytotoxicity in nasal mucosa
Lee MG; Wheelock AM; Boland B; Plopper CG
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2006;114(9):1354-1360
The role of lnflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways
Schmelzer KR; Wheelock AM; Dettmer K; Morin D; Hammock BD
Article: PROTEOMICS. 2006;6(5):1385-1398
Use of a fluorescent internal protein standard to achieve quantitative two-dimensional gel electrophoresis
Wheelock AM; Morin D; Bartosiewicz M; Buckpitt AR
Article: ELECTROPHORESIS. 2005;26(23):4508-4520
Software-induced variance in two-dimensional gel electrophoresis image analysis
Wheelock Å; Buckpitt AR
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2005;33(2):130-137
In vivo effects of ozone exposure on protein adduct formation by 1-nitronaphthalene in rat lung
Wheelock Å; Boland BC; Isbell M; Morin D; Wegesser TC; Plopper CG; Buckpitt AR
Article: AMERICAN JOURNAL OF PHYSIOLOGY - LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2004;286(2):L399-L410
Isolation of rodent airway epithelial cell proteins facilitates in vivo proteomics studies of lung toxicity
Wheelock Å; Zhang L; Tran MU; Morin D; Penn S; Buckpitt AR; Plopper CG
Article: ANALYTICAL BIOCHEMISTRY. 2003;315(2):208-222
Evaluation of α-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes
Wheelock CE; Wheelock Å; Zhang R; Stok JE; Morisseau C; Le Valley SE; Green CE; Hammock BD
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Review: BRIEFINGS IN BIOINFORMATICS. 2023;25(1):bbad478
Diagnostic Prediction of portal vein thrombosis in chronic cirrhosis patients using data-driven precision medicine model
Li Y; Gao J; Zheng X; Nie G; Qin J; Wang H; He T; Wheelock A; Li C-X; Cheng L; Li X
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa2971
Consensus clustering with missing labels (ccml): a consensus clustering tool for multiomics integrative prediction in cohorts with unequal sample coverage
Li C-X; Chen H; Skold CM; Zhou M; Wheelock A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa2967
miRNA identification in Particles in Exhaled Air (PExA) to study lung diseases
Bonatti M; Ezerskyte M; Lindberg P; Wheelock AM
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa2904
Literature-mining in research of Post-Acute Sequelae of Covid-19
Piontkovskaya K; Chuan-Xing L; Luo Y; Runold M; Wheelock AM
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa2220
Late Breaking Abstract - HLA-DR immunopeptidomics on cells from bronchoalveolar lavage
Zohrer B; Vegvari A; Grunewald J; Wheelock AM
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a4794
The Swedish Broncho-Scapis Cohort: Characterization of Chronic Airflow Limitation in Adult Never-Smokers
Pincikova T; Andersson A; Bjermer LH; Blomberg AC; Erjefalt J; Janson C; Persson HL; Tufvesson E; Wheelock A; Skold C
Conference publication: 2023
Multiomics integration-based molecular characterizations in COPD and post-COVID
Wheelock ÅM
Letter: EUROPEAN RESPIRATORY JOURNAL. 2022;59(1):2102603
A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes
Abdel-Aziz MI; Vijverberg SJH; Neerincx AH; Brinkman P; Wagener AH; Riley JH; Sousa AR; Bates S; Wagers SS; De Meulder B; Auffray C; Wheelock AM; Bansal AT; Caruso M; Chanez P; Uddin M; Corfield J; Horvath I; Krug N; Musial J; Sun K; Shaw DE; Sandstrom T; Montuschi P; Fowler SJ; Lutter R; Djukanovic R; Howarth P; Skipp P; Sanak M; Adcock IM; Chung KF; Sterk PJ; Kraneveld AD; der Zee AHM-V
Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;76(1):380-383
Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics
Zounemat Kermani N; Saqi M; Agapow P; Pavlidis S; Kuo C; Tan KS; Mumby S; Sun K; Loza M; Baribaud F; Sousa AR; Riley J; Wheelock AM; Wheelock CE; De Meulder B; Schofield J; Sanchez-Ovando S; Simpson JL; Baines KJ; Wark PA; Auffray C; Dahlen S-E; Sterk PJ; Djukanovic R; Adcock IM; Guo Y-K; Chung KF
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2020;56:4714
Late Breaking Abstract - Increased serum levels of YKL-40 in male smoking chronic obstructive pulmonary disease patients associated with altered miRNA levels in alveolar macrophages
Zohrer B; James A; Souihi N; Brundin B; Karimi R; Erle DJ; Dahlen S-E; Skold CM; Wheelock AM
Preprint: BIORXIV. 2020
Decreased miR-24-3p potentiates DNA damage responses and increases susceptibility to COPD
Nouws J; Wan F; Finnemore E; Roque W; Kim S; Bazan I; Li C-X; Skold CM; Yan X; Neumeister V; Britto CJ; Sweasy J; Bindra R; Wheelock ÅM; Gomez-Villalobos J; Kaminski N; Lee PJ; Sauler M
Conference publication: 2019;:pa4349
Alterations in measures of systemic inflammation among adults born preterm
Gao J; Um-Bergström P; Pourbazargan M; Berggren-Broström E; Merikallio H; Kaarteenaho R; Reinke S; Wheelock C; Melén E; Lindén A; Wheelock A; Sköld M
Editorial comment: EUROPEAN RESPIRATORY JOURNAL. 2019;53(3):1900217
Chronic Airway Diseases Early Stratification (CADSET): a new ERS Clinical Research Collaboration
Agusti A; Faner R; Donaldson G; Heuvelin E; Breyer-Kohansal R; Melen E; Maitland-van der Zee AH; Vestbo J; Allinson JP; Vanfleteren LEGW; van den Berge M; Adcock IM; Lahousse L; Brusselle G; Wedzicha JA; Alter P; Barbe F; Brightling CE; Breyer M-K; Burghuber OC; Casas M; Chung KF; Cosio BG; Crispi F; de Batlle J; Fitting J-W; Garcia J; Hallberg J; Hartl S; Jarvis D; Mathioudakis A; Nicod L; Papi A; Ritchie A; Sigsgaard T; Sterk PJ; Ullman A; Vellve K; Vogelmeier C; Wheelock AM; Wheelock CE; Spanevello A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa960
T-cell subsets in bronchoalveolar lavage fluid from adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Pourbazargan M; Levanen B; Strom M; Berggren-Brostroom E; Melen E; Wheelock A; Linden A; Skold M
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa5480
Interleukin-26 in airway morbidities of long-term tobacco smokers
Che K; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold MC; Linden A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:oa4920
Late Breaking Abstract - Elevated airway lymphocytes in adults born prematurely with a history of bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Merikallio H; Kaarteenaho R; Reinke S; Wheelock CE; Melen E; Linden A; Wheelock AM; Skold CM
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:oa3578
U-BIOPRED accessible handprint: combining omics platforms to identify stable asthma subphenotypes
De Meulder B; Yen RTC; Li C-X; Wheelock A; Chung KF; Adcock I; Djukjanovic R; Wagers S; Riley J; Erpenbeck V; Bakke P; Caruso M; Chanez P; Dahlen S-E; Fowler S; Horvath I; Krug N; Montuschi P; Sanak M; Sandstrom T; Shaw D; Singer F; Pandis I; Bansal A; Sterk P; Baribaud F; Auffray C
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1980
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson M; Nyren S; Lilja G; Linden A; Wheelock A; Melen E; Skold M
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2018;197
Proteomic Profiling of the Airway Epithelium in COPD Reveals Sex-Enhanced Alterations Linked to Xenobiotic Metabolism and ER Stress, Correlated to Airway Wall Thickening and Goblet Cell Density in Women
Wheelock AM; Heyder T; Yang M; Kohler M; Merikallio H; Li C; Karimi R; Sihlbom C; Nyren S; Skold CM
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa851
LATE-BREAKING ABSTRACT: Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD
Balgoma D; Yang M; Sjodin M; Snowden S; Karimi R; Levanen B; Merikallio H; Kaarteenaho R; Palmberg L; Larsson K; Erle D; Dahlen S-E; Dahlen B; Skold M; Wheelock A; Wheelock C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):470
Method Development for the Identification of HLA-DR-Bound Peptides
Heyder T; Kohler M; Wheelock A; Wahlstrom J; Eklund A; Zubarev R; Grunewald J; Ytterberg J
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;189
Identification Of Smokers At Elevated Risk Of Developing COPD Through Bal Cell Proteome Characterization
Kohler M; Nyren S; Karimi R; Thomas A; Grunewald J; Eklund A; Thevis M; Skold CM; Wheelock AM
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;189
Lipid Mediator Levels Evidence Gender-Specific Increases In Bronchoalveolar Lavage Fluid Of COPD Patients Relative To Healthy Smokers
Wheelock C; Balgoma D; Skold M; Wheelock A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2014;44
Quantitative measurement of air trapping in smokers and its correlation to inflammatory cells in the lower respiratory tract
Karimi R; Nyren S; Wheelock A; Tornling G; Skold M
Editorial comment: MOLECULAR BIOSYSTEMS. 2013;9(11):2589-2596
Trials and tribulations of 'omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine
Wheelock AM; Wheelock CE
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2013;42
Lipid mediator levels evidence gender-specific increases in bronchoalveolar lavage fluid of COPD patients relative to healthy smokers
Wheelock C; Balgoma D; Grunewald J; Eklund A; Skold M; Wheelock A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2013;42
Alterations of the soluble proteome of airway epithelial cells in COPD
Heyder T; Kohler M; Karimi R; Levanen B; Eklund A; Grunewald J; Skold M; Wheelock A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2013;187
Quantitative Analysis Of The Soluble Proteome Of Airway Epithelial Cells In COPD
Heyder T; Kohler M; Karimi R; Levanen B; Eklund A; Grunewald J; Skold CM; Wheelock AM
Review: CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 2011;12(7):1026-1052
Lipid Mediator Profiling in Pulmonary Disease
Lundstrom SL; Balgoma D; Wheelock AM; Haeggstrom JZ; Dahlen S-E; Wheelock CE
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2011;183:a4447
Allergic Asthmatics Exhibit Altered Response In Oxylipin Profile As Compared To Healthy And Asthmatic Controls After Allergen Provocation
Lundstrom S; Yang J; Haeggstrom JZ; Hammock BD; Grunewald J; Nord M; van Hage M; Eklund A; Wheelock CE; Wheelock AM
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010;181:a2817
Difference In Oxylipin Levels And Exosome Content In Bronchoalveolar Lavage Fluid Of Asthmatics And Healthy Individuals In Response To Subway Air Exposure
Levanen B; Lundstrom SL; Paredes PT; Nording ML; Nystrom AK; Skold MC; Haeggstroem JZ; Grunewald J; Svartengren M; Hammock BD; Gabrielsson S; Larsson B; Eklund A; Wheelock CE; Erle DJ; Wheelock AM
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010;181:a1409
Altered Subgroups Of Intraepithelial (CD103+) T Cells In The Airways Of Smokers
Mikko M; Wahlstrom J; Cui L; Grunewald J; Wheelock AM; Skold MC
Conference publication: PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. 2010;7568:756811-756811-5-756811
The use of time-resolved fluorescence in gel-based proteomics for improved biomarker discovery
Sandberg A; Buschmann V; Kapusta P; Erdmann R; Wheelock ÅM
Conference publication: PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. 2010;7569:756931-756931-8-756931
Fast rasterscanning enables FLIM in macroscopic samples up to several centimeters
Koberling F; Buschmann V; Hille C; Patting M; Dosche C; Sandberg A; Wheelock A; Erdmann R
Review: MOLECULAR BIOSYSTEMS. 2010;6(2):289-304
The use of network analyses for elucidating mechanisms in cardiovascular disease
Diez D; Wheelock AM; Goto S; Haeggstrom JZ; Paulsson-Berne G; Hansson GK; Hedin U; Gabrielsen A; Wheelock CE
Review: TOXICOLOGY. 2009;260(1-3):16-27
Toxicity and metabolism of methylnaphthalenes: Comparison with naphthalene and 1-nitronaphthalene
Lin CY; Wheelock AM; Morin D; Baldwin RM; Lee MG; Taff A; Plopper C; Buckpitt A; Rohde A
Review: MOLECULAR BIOSYSTEMS. 2009;5(6):588-602
Systems biology approaches and pathway tools for investigating cardiovascular disease
Wheelock CE; Wheelock AM; Kawashima S; Diez D; Kanehisa M; van Erk M; Kleemann R; Haeggstrom JZ; Goto S
Editorial comment: IDRUGS : THE INVESTIGATIONAL DRUGS JOURNAL. 2008;11(11):799-802
From Genome to Proteome: Integration and proteome completion-8th Siena Meeting
Wheelock AM; Wheelock CE
Book chapter: PLANT PROTEOMICS. 2008;p. 105-125
Bioinformatics in Gel‐Based Proteomics
Wheelock ÅM; Wheelock CE
Conference publication: GENOME INFORMATICS. INTERNATIONAL CONFERENCE ON GENOME INFORMATICS. 2008;20:64-76
A framework for determining outlying microarray experiments.
Wan R; Wheelock AM; Mamitsuka H
Review: EXPERT REVIEW OF PROTEOMICS. 2006;3(1):129-142
Effects of post-electrophoretic analysis on variance in gel-based proteomics
Wheelock AM; Goto S
Review: JOURNAL OF PESTICIDE SCIENCE. 2006;31(3):263-272
Enlistment of omics technologies in the fight against malaria:: Panacea or Pandora's Box?
Hayes CN; Wheelock AM; Normark J; Wahlgren M; Goto S; Wheelock CE
Review: DRUG METABOLISM REVIEWS. 2002;34(4):791-820
Naphthalene-induced respiratory tract toxicity: Metabolic mechanisms of toxicity
Buckpitt A; Boland B; Isbell M; Morin D; Shultz M; Baldwin R; Chan K; Karlsson A; Lin C; Taff A; West J; Fanucchi M; Van Winkle L; Plopper C
Published conference paper: CHEMICO-BIOLOGICAL INTERACTIONS. 2001;133(1-3):102-105
Determination of interindividual variation in glutathione transferase P1 mRNA expression and enzyme activity in human peripheral blood cells
Warholm M; Karlsson Å; Tuominen R; Rannug A
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Forskningsbidrag

Home monitoring and molecular phenotyping of patients with long-COVID for sub-grouping and follow-up of efficacy of interventions
Swedish Research Council
1 December 2021 - 30 November 2025
Hem-monitorering och molekylär fenotypning av patienter med långtids-COVID för subgruppering samt uppföljning av interventioner
Swedish Heart-Lung Foundation
1 January 2021 - 31 December 2021
Kronisk luftvägsobstruktion: klinik, mekanismer och bakomliggande faktorer
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
COPD Sub-phenotypes: A Systems Medicine Framework for Investigating autoimmune components of Chronic Obstructive Pulmonary Disease (COPD)
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
COPD Sub-phenotypes: A Systems Medicine Framework for Investigating autoimmune components of Chronic Obstructive Pulmonary Disease (COPD)
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
COPD Sub-phenotypes: A Systems Medicine Framework for Investigating Molecularly & Mechanistically Distinct Groups of Obstructive Lung Disease in Never-smokers
Swedish Research Council
1 January 2019 - 31 December 2024
Molecular alterations in lung immune cells related to early onset COPD in prematurely born young adults
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2020
Molecular phenotyping of endemic lung diseases (MORPHEUS)
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2021
COPD Sub-phenotypes: A Systems Medicine Approach for Investigating Molecularly & Mechanistically Distinct Groups of Obstructive Lung Disease in Never-smokers
Swedish Research Council
1 January 2018 - 31 December 2020
Early detection of adverse effects on thesmall airways due to occupational exposure
Swedish Research Council for Health Working Life and Welfare
1 January 2017 - 31 December 2019
COPD Sub-phenotypes: A Systems Biology Approach to Investigating Phenotypic & Mechanistic Gender Differences in Chronic Obstructive Pulmonary Disease
Swedish Research Council
1 January 2013 - 31 December 2017
COPD AND GENDER: A SYSTEMS BIOLOGY APPROACH
VINNOVA
1 December 2008 - 30 June 2012

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