Annika Jenmalm Jensen

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: NUCLEIC ACIDS RESEARCH (NAR). 2022;50(22):e129
Monitoring drug-target interactions through target engagement-mediated amplification on arrays and in situ
Al-Amin RA; Johansson L; Abdurakhmanov E; Landegren N; Lof L; Arngarden L; Blokzijl A; Svensson R; Hammond M; Lonn P; Haybaeck J; Kamali-Moghaddam M; Jensen AJ; Danielson UH; Artursson P; Lundback T; Landegren U
Article: TUBERCULOSIS. 2022;135:102222
A high content screening assay for discovery of antimycobacterial compounds based on primary human macrophages infected with virulent Mycobacterium tuberculosis
Kalsum S; Otrocka M; Andersson B; Welin A; Schon T; Jenmalm-Jensen A; Lundback T; Lerm M
Article: ACS OMEGA. 2019;4(7):11642-11656
Computational and Experimental Druggability Assessment of Human DNA Glycosylases
Michel M; Visnes T; Homan EJ; Seashore-Ludlow B; Hedenstrom M; Wiita E; Vallin K; Paulin CBJ; Zhang J; Wallner O; Scobie M; Schmidt A; Jenmalm-Jensen A; Berglund UW; Helleday T
Article: SCIENCE. 2018;362(6416):834-839
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
Visnes T; Cazares-Korner A; Hao W; Wallner O; Masuyer G; Loseva O; Mortusewicz O; Wiita E; Sarno A; Manoilov A; Astorga-Wells J; Jemth A-S; Pan L; Sanjiv K; Karsten S; Gokturk C; Grube M; Homan EJ; Hanna BMF; Paulin CBJ; Pham T; Rasti A; Berglund UW; von Nicolai C; Benitez-Buelga C; Koolmeister T; Ivanic D; Iliev P; Scobie M; Krokan HE; Baranczewski P; Artursson P; Altun M; Jensen AJ; Kalderen C; Ba X; Zubarev RA; Stenmark P; Boldogh I; Helleday T
Article: MOLECULAR METABOLISM. 2018;9:28-42
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
Pettersson-Klein AT; Izadi M; Ferreira DMS; Cervenka I; Correia JC; Martinez-Redondo V; Southern M; Cameron M; Kamenecka T; Agudelo LZ; Porsmyr-Palmertz M; Martens U; Lundgren B; Otrocka M; Jenmalm-Jensen A; Griffin PR; Ruas JL
Article: ORGANIC AND BIOMOLECULAR CHEMISTRY. 2017;15(37):7758-7764
Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction
Llona-Minguez S; Throup A; Steiner E; Lightowler M; Van der Haegen S; Homan E; Eriksson L; Stenmark P; Jenmalm-Jensen A; Helleday T
Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2017;27(15):3219-3225
Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems
Llona-Minguez S; Haggblad M; Martens U; Johansson L; Sigmundsson K; Lundback T; Loseva O; Jemth A-S; Lundgren B; Jensen AJ; Scobie M; Helleday T
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2017;60(10):4279-4292
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
Llona-Minguez S; Hoglund A; Ghassemian A; Desroses M; Calderon-Montano JM; Moron EB; Valerie NCK; Wiita E; Almlof I; Koolmeister T; Mateus A; Cazares-Korner C; Sanjiv K; Homan E; Loseva O; Baranczewski P; Darabi M; Mehdizadeh A; Fayezi S; Jemth A-S; Berglund UW; Sigmundsson K; Lundback T; Jensen AJ; Artursson P; Scobie M; Helleday T
Article: CANCER RESEARCH. 2017;77(7):1741-1752
Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Niklasson M; Maddalo G; Sramkova Z; Mutlu E; Wee S; Sekyrova P; Schmidt L; Fritz N; Dehnisch I; Kyriatzis G; Krafcikova M; Carson BB; Feenstra JM; Marinescu VD; Segerman A; Haraldsson M; Gustavsson A-L; Hammarstrom LGJ; Jensen AJ; Uhrbom L; Altelaar AFM; Linnarsson S; Uhlen P; Trantirek L; Vincent CT; Nelander S; Enger PO; Andang M
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2017;60(5):2148-2154
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
Llona-Minguez S; Hoglund A; Wiita E; Almlof I; Mateus A; Calderon-Montano JM; Cazares-Korner C; Homan E; Loseva O; Baranczewski P; Jemth A-S; Haggblad M; Martens U; Lundgren B; Artursson P; Lundback T; Jensen AJ; Berglund UW; Scobie M; Helledayt T
Article: ACS CHEMICAL NEUROSCIENCE. 2016;7(10):1383-1392
Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures
Diwakarla S; Nylander E; Gronbladh A; Vanga SR; Khan YS; Gutierrez-de-Teran H; Savmarker J; Ng L; Vi P; Lundback T; Jenmalm-Jensen A; Svensson R; Artursson P; Zelleroth S; Engen K; Rosenstrom U; Larhed M; Aqvist J; Chai SY; Hallberg M
Article: MOLECULAR PHARMACOLOGY. 2016;89(4):413-424
Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density
Diwakarla S; Nylander E; Gronbladh A; Vanga SR; Khan YS; Gutierrez-de-Teran H; Ng L; Vi P; Savmarker J; Lundback T; Jenmalm-Jensen A; Andersson H; Engen K; Rosenstrom U; Larhed M; Aqvist J; Chai SY; Hallberg M
Article: ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES. 2016;14(3):180-193
Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening
Engen K; Rosenstrom U; Axelsson H; Konda V; Dahllund L; Otrocka M; Sigmundsson K; Nikolaou A; Vauquelin G; Hallberg M; Jenmalm Jensen A; Lundback T; Larhed M
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2016;59(3):1140-1148
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Llona-Minguez S; Hoglund A; Jacques SA; Johanson L; Calderon-Montano JM; Claesson M; Loseva O; Valerie NCK; Lundback T; Piedrafita J; Maga G; Crespan E; Meijer L; Moron EB; Baranczewski P; Hagbjork A-L; Svensson R; Wiita E; Almlof I; Visnes T; Jeppsson F; Sigmundsson K; Jensen AJ; Artursson P; Jemth A-S; Stenmark P; Berglund UW; Scobie M; Helleday T
Article: CHEMISTRYOPEN. 2014;3(6):256-263
Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides
Borhade SR; Rosenstrom U; Savmarker J; Lundback T; Jenmalm-Jensen A; Sigmundsson K; Axelsson H; Svensson F; Konda V; Skold C; Larhed M; Hallberg M
Article: ORGANIC PROCESS RESEARCH AND DEVELOPMENT. 2014;18(11):1582-1588
Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors
Engen K; Savmarker J; Rosenstrom U; Wannberg J; Lundback T; Jenmalm-Jensen A; Larhed M
Article: NATURE. 2014;508(7495):215-221
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Gad H; Koolmeister T; Jemth A-S; Eshtad S; Jacques SA; Strom CE; Svensson LM; Schultz N; Lundback T; Einarsdottir BO; Saleh A; Gokturk C; Baranczewski P; Svensson R; Berntsson RP-A; Gustafsson R; Stromberg K; Sanjiv K; Jacques-Cordonnier M-C; Desroses M; Gustavsson A-L; Olofsson R; Johansson F; Homan EJ; Loseva O; Brautigam L; Johansson L; Hoglund A; Hagenkort A; Pham T; Altun M; Gaugaz FZ; Vikingsson S; Evers B; Henriksson M; Vallin KSA; Wallner OA; Hammarstrom LGJ; Wiita E; Almlof I; Kalderen C; Axelsson H; Djureinovic T; Puigvert JC; Haggblad M; Jeppsson F; Martens U; Lundin C; Lundgren B; Granelli I; Jensen AJ; Artursson P; Nilsson JA; Stenmark P; Scobie M; Berglund UW; Helleday T
Article: BLOOD CANCER JOURNAL. 2012;2(8):e81
The novel tyrosine kinase inhibitor AKN-028 has significant antileukemic activity in cell lines and primary cultures of acute myeloid leukemia
Eriksson A; Hermanson M; Wickstrom M; Lindhagen E; Ekholm C; Jensen AJ; Lothgren A; Lehmann F; Larsson R; Parrow V; Hoglund M
Article: BIOCHEMICAL PHARMACOLOGY. 2012;83(12):1655-1662
A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1
Cevik-Aras H; Kalderen C; Jensen AJ; Oprea T; Dahlgren C; Forsman H
Article: BIOCHEMICAL PHARMACOLOGY. 2011;81(3):402-411
Stable formyl peptide receptor agonists that activate the neutrophil NADPH-oxidase identified through screening of a compound library
Forsman H; Kalderen C; Nordin A; Nordling E; Jensen AJ; Dahlgren C
Article: BIOCHEMICAL PHARMACOLOGY. 2010;80(10):1507-1516
Identification of AKN-032, a novel 2-aminopyrazine tyrosine kinase inhibitor, with significant preclinical activity in acute myeloid leukemia
Eriksson A; Hoglund M; Lindhagen E; Aleskog A; Hassan SB; Ekholm C; Fholenhag K; Jensen AJ; Lothgren A; Scobie M; Larsson R; Parrow V
Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2009;19(20):5861-5863
Small kinase assay panels can provide a measure of selectivity
Brandt P; Jensen AJ; Nilsson J
Article: TETRAHEDRON. 2006;62(15):3600-3609
Peracid dependent stereoselectivity and functional group contribution to the stereocontrol of epoxidation of (E)-alkene dipeptide isosteres
Wiktelius D; Berts W; Jensen AJ; Gullbo J; Saitton S; Csöregh I; Luthman K
Article: TETRAHEDRON LETTERS. 1998;39(20):3213-3214
Diastereoselective peracid epoxidation: Control of the face selectivity via functional group tuning and proper choice of epoxidation reagent
Jensen AJ; Luthman K
Article: JOURNAL OF ORGANIC CHEMISTRY. 1995;60(4):1026-1032
STEREOSELECTIVE EPOXIDATION OF ALLYLIC CARBAMATES WITH M-CHLOROPERBENZOIC ACID - THE ROLE OF COOPERATIVE COORDINATION
JENMALM A; BERTS W; LUTHMAN K; CSOREGH I; HACKSELL U
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Corrigendum: JOURNAL OF MEDICINAL CHEMISTRY. 2017;60(17):7614
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors (vol 60, pg 4279, 2017)
Llona-Minguez S; Hoglund A; Ghassemian A; Desroses M; Calderon-Montano JM; Moron EB; Valerie NCK; Wiita E; Almlof I; Koolmeister T; Mateus A; Cazares-Korner C; Sanjiv K; Homan E; Loseva O; Baranczewski P; Darabi M; Mehdizadeh A; Fayezi S; Jemth A-S; Berglund UW; Sigmundsson K; Lundback T; Jensen AJ; Artursson P; Scobie M; Helleday T
Corrigendum: NATURE. 2017;544(7651):508
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool (vol 508, pg 215, 2014)
Gad H; Koolmeister T; Jemth A-S; Eshtad S; Jacques SA; Strom CE; Svensson LM; Schultz N; Lundback T; Einarsdottir BO; Saleh A; Gokturk C; Baranczewski P; Svensson R; Berntsson RP-A; Gustafsson R; Stromberg K; Sanjiv K; Jacques-Cordonnier M-C; Desroses M; Gustavsson A-L; Olofsson R; Johansson F; Homan EJ; Loseva O; Brautigam L; Johansson L; Hoglund A; Hagenkort A; Pham T; Altun M; Gaugaz FZ; Vikingsson S; Evers B; Henriksson M; Vallin KSA; Wallner OA; Hammarstrom LGJ; Wiita E; Almlof I; Kalderen C; Axelsson H; Djureinovic T; Puigvert JC; Haggblad M; Jeppsson F; Martens U; Lundin C; Lundgren B; Granelli I; Jensen AJ; Artursson P; Nilsson JA; Stenmark P; Scobie M; Berglund UW; Helleday T
Editorial comment: FUTURE MEDICINAL CHEMISTRY. 2015;7(8):975-978
CETSA: a target engagement assay with potential to transform drug discovery
Jensen AJ; Molina DM; Lundback T
Editorial comment: ACS CHEMICAL BIOLOGY. 2013;8(12):2605-2606
Chemical Biology Consortium Sweden
Hammarstrom LGJ; Jensen AJ

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