Anna-Lena Gustavsson

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: AUTOPHAGY. 2022;18(7):1486-1502
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
Giovannucci TA; Salomons FA; Stoy H; Herzog LK; Xu S; Qian W; Merino LG; Gierisch ME; Haraldsson M; Lystad AH; Uvell H; Simonsen A; Gustavsson A-L; Vallin M; Dantuma NP
Article: CELL DEATH AND DISEASE. 2021;12(10):914
Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound
Giovannucci TA; Salomons FA; Haraldsson M; Elfman LHM; Wickstroem M; Young P; Lundbaeck T; Eirich J; Altun M; Jafari R; Gustavsson A-L; Johnsen JI; Dantuma NP
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(8):3915-3934
Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability
Popova G; Ladds MJGW; Johansson L; Saleh A; Larsson J; Sandberg L; Sahlberg SH; Qian W; Gullberg H; Garg N; Gustavsson A-L; Haraldsson M; Lane D; Yngve U; Lain S
Article: NATURE COMMUNICATIONS. 2020;11(1):1308
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
Rendo V; Stoimenov I; Mateus A; Sjoberg E; Svensson R; Gustavsson A-L; Johansson L; Ng A; O'Brien C; Giannakis M; Artursson P; Nygren P; Cheong I; Sjoblom T
Article: FRONTIERS IN CHEMISTRY. 2020;8:443
In silicoDruggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization
Michel M; Homan EJ; Wiita E; Pedersen K; Almlof I; Gustavsson A-L; Lundback T; Helleday T; Berglund UW
Article: CHEMICAL BIOLOGY AND DRUG DESIGN. 2018;92(1):1255-1271
Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening
Reithmeier A; Lundback T; Haraldsson M; Frank M; Ek-Rylander B; Nyholm P-G; Gustavsson A-L; Andersson G
Article: NATURE COMMUNICATIONS. 2018;9(1):1107
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S
Article: CELL CHEMICAL BIOLOGY. 2018;25(2):224-229.e2
Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions
Tang J; Tanoli Z-U; Ravikumar B; Alam Z; Rebane A; Vaha-Koskela M; Peddinti G; van Adrichem AJ; Wakkinen J; Jaiswal A; Karjalainen E; Gautam P; He L; Parri E; Khan S; Gupta A; Ali M; Yetukuri L; Gustavsson A-L; Seashore-Ludlow B; Hersey A; Leach AR; Overington JP; Repasky G; Wennerberg K; Aittokallio T
Article: NATURE COMMUNICATIONS. 2018;9(1):250
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Page BDG; Valerie NCK; Wright RHG; Wallner O; Isaksson R; Carter M; Rudd SG; Loseva O; Jemth A-S; Almlof I; Font-Mateu J; Llona-Minguez S; Baranczewski P; Jeppsson F; Homan E; Almqvist H; Axelsson H; Regmi S; Gustavsson A-L; Lundback T; Scobie M; Stromberg K; Stenmark P; Beato M; Helleday T
Article: BMC BIOLOGY. 2017;15(1):88
A Drosophila female pheromone elicits species-specific long-range attraction via an olfactory channel with dual specificity for sex and food
Lebreton S; Borrero-Echeverry F; Gonzalez F; Solum M; Wallin EA; Hedenstrom E; Hansson BS; Gustavsson A-L; Bengtsson M; Birgersson G; Walker WBIII; Dweck HKM; Becher PG; Witzgall P
Article: ORGANIC AND BIOMOLECULAR CHEMISTRY. 2017;15(21):4644-4654
High-affinity recognition of the human C-reactive protein independent of phosphocholine
Yang J; Gustavsson A-L; Haraldsson M; Karlsson G; Norberg T; Baltzer L
Article: ONCOTARGET. 2017;8(14):23713-23726
dUTPase inhibition augments replication defects of 5-Fluorouracil
Hagenkort A; Paulin CBJ; Desroses M; Sarno A; Wiita E; Mortusewicz O; Koolmeister T; Loseva O; Jemth A-S; Almlof I; Homan E; Lundback T; Gustavsson A-L; Scobie M; Helleday T
Article: CANCER RESEARCH. 2017;77(7):1741-1752
Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses
Niklasson M; Maddalo G; Sramkova Z; Mutlu E; Wee S; Sekyrova P; Schmidt L; Fritz N; Dehnisch I; Kyriatzis G; Krafcikova M; Carson BB; Feenstra JM; Marinescu VD; Segerman A; Haraldsson M; Gustavsson A-L; Hammarstrom LGJ; Jensen AJ; Uhrbom L; Altelaar AFM; Linnarsson S; Uhlen P; Trantirek L; Vincent CT; Nelander S; Enger PO; Andang M
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2016;59(14):6848-6859
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis
Brunner K; Maric S; Reshma RS; Almqvist H; Seashore-Ludlow B; Gustavsson A-L; Poyraz O; Yogeeswari P; Lundback T; Vallin M; Sriram D; Schnell R; Schneider G
Article: CHEMMEDCHEM. 2014;9(10):2309-2326
Design of a General-Purpose European Compound Screening Library for EU-OPENSCREEN
Horvath D; Lisurek M; Rupp B; Kuehne R; Specker E; von Kries J; Rognan D; Andersson CD; Almqvist F; Elofsson M; Enqvist P-A; Gustavsson A-L; Remez N; Mestres J; Marcou G; Varnek A; Hibert M; Quintana J; Frank R
Article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2014;63(6):627-641
Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation
Theorell J; Gustavsson A-L; Tesi B; Sigmundsson K; Ljunggren H-G; Lundbaeck T; Bryceson YT
Article: NATURE. 2014;508(7495):215-221
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Gad H; Koolmeister T; Jemth A-S; Eshtad S; Jacques SA; Strom CE; Svensson LM; Schultz N; Lundback T; Einarsdottir BO; Saleh A; Gokturk C; Baranczewski P; Svensson R; Berntsson RP-A; Gustafsson R; Stromberg K; Sanjiv K; Jacques-Cordonnier M-C; Desroses M; Gustavsson A-L; Olofsson R; Johansson F; Homan EJ; Loseva O; Brautigam L; Johansson L; Hoglund A; Hagenkort A; Pham T; Altun M; Gaugaz FZ; Vikingsson S; Evers B; Henriksson M; Vallin KSA; Wallner OA; Hammarstrom LGJ; Wiita E; Almlof I; Kalderen C; Axelsson H; Djureinovic T; Puigvert JC; Haggblad M; Jeppsson F; Martens U; Lundin C; Lundgren B; Granelli I; Jensen AJ; Artursson P; Nilsson JA; Stenmark P; Scobie M; Berglund UW; Helleday T
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2013;56(24):9861-9873
Structure-Activity Relationships of Synthetic Cordycepin Analogues as Experimental Therapeutics for African Trypanosomiasis
Vodnala SK; Lundback T; Yeheskieli E; Sjoberg B; Gustavsson A-L; Svensson R; Olivera GC; Eze AA; de Koning HP; Hammarstrom LGJ; Rottenberg ME
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(38):27456-27468
Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase of Trypanosoma brucei
Lu J; Vodnala SK; Gustavsson A-L; Gustafsson TN; Sjoberg B; Johansson HA; Kumar S; Tjernberg A; Engman L; Rottenberg ME; Holmgren A
Article: CHEMMEDCHEM. 2013;8(8):1283-1294
Design of a Highly Selective and Potent Class of Non-planar Estrogen Receptor Agonists
Sunden H; Ma J-N; Hansen LK; Gustavsson A-L; Burstein ES; Olsson R
Article: RSC MEDICINAL CHEMISTRY. 2013;4(11):1439-1442
The A-CD analogue of 16β,17α-estriol is a potent and highly selective estrogen receptor β agonist
Sauvee C; Schafer A; Sunden H; Ma J-N; Gustavsson A-L; Burstein ES; Olsson R
Article: PROTEIN EXPRESSION AND PURIFICATION. 2006;46(2):321-331
Production of a truncated soluble human semicarbazide-sensitive amine oxidase mediated by a GST-fusion protein secreted from HEK293 cells
Öhman J; Jakobsson E; Kdllström U; Elmblad A; Ansari A; Kalderén C; Robertson E; Danielsson E; Gustavsson AL; Varadi A; Ekbloin J; Holmgren E; Doverskog M; Abrahmsén L; Nilsson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(39):41124-41130
A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects
Östberg T; Svensson S; Selén G; Uppenberg J; Thor M; Sundbom M; Sydow-Bäckman M; Gustavsson AL; Jendeberg L
Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2002;12(24):3565-3567
Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators
Thor M; Beierlein K; Dykes G; Gustavsson AL; Heidrich J; Jendeberg L; Lindqvist B; Pegurier C; Roussel P; Slater M; Svensson S; Sydow-Bäckman M; Thornström U; Uppenberg J
Article: JOURNAL OF CHEMICAL ECOLOGY. 1997;23(12):2755-2776
Bioisosteric approach to elucidation of binding of the acetate group of a moth sex pheromone component to its receptor
Gustavsson AL; Tuvesson M; Larsson MC; Wu WQ; Hansson BS; Liljefors T
Article: BIOORGANIC AND MEDICINAL CHEMISTRY. 1997;5(12):2173-2183
Enantiomers of cis- and trans-3-(4-propyl-cyclopent-2-enyl)propyl acetate. A study on the bioactive conformation and chiral recognition of a moth sex pheromone component
Gustavsson AL; Larsson MC; Hansson BS; Liljefors T
Article: JOURNAL OF CHEMICAL ECOLOGY. 1997;23(12):2917-2934
A 3D-QSAR study of analogs of (Z)-5-decenyl acetate, a pheromone component of the turnip moth, Agrotis segetum
Norinder U; Gustavsson AL; Liljefors T
Article: JOURNAL OF CHEMICAL ECOLOGY. 1995;21(6):815-832
ALKYL ETHER AND ENOL ETHER ANALOGS OF (Z)-5-DECENYL ACETATE, A PHEROMONE COMPONENT OF THE TURNIP MOTH, AGROTIS-SEGETUM - PROBING A PROPOSED BIOACTIVE BIOACTIVE CONFORMATION FOR CHAIN-ELONGATED ANALOGS
GUSTAVSSON AL; LILJEFORS T; HANSSON BS
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Corrigendum: NATURE COMMUNICATIONS. 2019;10(1):5050
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells (vol 9, 250, 2018)
Page BDG; Valerie NCK; Wright RHG; Wallner O; Isaksson R; Carter M; Rudd SG; Loseva O; Jemth A-S; Almlof I; Font-Mateu J; Llona-Minguez S; Baranczewski P; Jeppsson F; Homan E; Almqvist H; Axelsson H; Regmi S; Gustavsson A-L; Lundback T; Scobie M; Stromberg K; Stenmark P; Beato M; Helleday T
Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):2071
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Fernandez AP; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Farnegardh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Hakansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Lain S

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