Amit Kumar

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

Akademiska priser och utmärkelser
Grants received from national and international foundations:

1. KID grant from Karolinska Doctoral Committee.

2. AARF grant from Alzheimer’s Association, USA.

3. Alzheimerfonden.

4. Åhléns Stiftelsen.

5. Magnus Bregvalls.

6. Demensförbundet.

7. Karolinska Institutet Geriatrics Foundation.

8. Tore Nilsons stiftelse för medicinsk forskning.

9. Gunvor och Josef Aners Stiftelse.

10. Loo och Hans Ostermans stiftelse för medicinsk forskning.

11. Stifelsen för Gamla Tjänarinnor.

12. Lars Hiertas Minne Stiftelse.

13. Gun and Bertil Stohnes Foundation.

14. Lindhes Advokatbyrå.

15. Karolinska Institutet Research Foundation.

16. Petrus och Augusta Hedlunds stiftelse.

Artiklar

Article: ALZHEIMER'S AND DEMENTIA. 2024;20(4):2589-2605
Tracing synaptic loss in Alzheimer's brain with SV2A PET-tracer UCB-J
Kumar A; Scarpa M; Nordberg A
Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(2):328-336
Multitracer Approach to Understanding the Complexity of Reactive Astrogliosis in Alzheimer's Brains
Fontana IC; Kumar A; Okamura N; Nordberg A
Article: METHODS IN MOLECULAR BIOLOGY. 2024;2785:195-218
Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach.
Rodriguez-Vieitez E; Kumar A; Malarte M-L; Ioannou K; Rocha FM; Chiotis K
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(18):3528-3539
Insight into the Binding of First- and Second-Generation PET Tracers to 4R and 3R/4R Tau Protofibrils
Li J; Kumar A; Langstrom B; Nordberg A; Agren H
Article: ACTA NEUROPATHOLOGICA. 2023;145(3):325-333
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains
Yang Y; Zhang W; Murzin AG; Schweighauser M; Huang M; Lovestam S; Peak-Chew SY; Saito T; Saido TC; Macdonald J; Lavenir I; Ghetti B; Graff C; Kumar A; Nordberg A; Goedert M; Scheres SHW
Article: MOLECULAR PSYCHIATRY. 2023;28(3):1272-1283
Discriminative binding of tau PET tracers PI2620, MK6240 and RO948 in Alzheimer's disease, corticobasal degeneration and progressive supranuclear palsy brains
Malarte M-L; Gillberg P-G; Kumar A; Bogdanovic N; Lemoine L; Nordberg A
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(11):6073
Allosteric Binding Sites of Aβ Peptides on the Acetylcholine Synthesizing Enzyme ChAT as Deduced by In Silico Molecular Modeling
Baidya ATK; Kumar A; Kumar R; Darreh-Shori T
Article: MOLECULAR PSYCHIATRY. 2021;26(10):5833-5847
Astroglial tracer BU99008 detects multiple binding sites in Alzheimer's disease brain
Kumar A; Koistinen NA; Malarte M-L; Nennesmo I; Ingelsson M; Ghetti B; Lemoine L; Nordberg A
Article: BIOCHEMICAL PHARMACOLOGY. 2020;182:114212
Esomeprazole reduces sperm motility index by targeting the spermic cholinergic machinery: A mechanistic study for the association between use of proton pump inhibitors and reduced sperm motility index
Kumar A; Kumar R; Flanagan J; Langstrom B; Bjorndahl L; Darreh-Shori T
Article: ALZHEIMER'S AND DEMENTIA. 2020;16(7):1031-1042
Proton pump inhibitors act with unprecedented potencies as inhibitors of the acetylcholine biosynthesizing enzyme-A plausible missing link for their association with incidence of dementia
Kumar R; Kumar A; Nordberg A; Langstrom B; Darreh-Shori T
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2019;11(1):80
Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas
Sinclair LI; Kumar A; Darreh-Shori T; Love S
Article: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2018;11:327
Soluble Aβ42 Acts as Allosteric Activator of the Core Cholinergic Enzyme Choline Acetyltransferase
Kumar A; Lana E; Kumar R; Lithner CU; Darreh-Shori T
Article: ACS CHEMICAL NEUROSCIENCE. 2017;8(12):2618-2625
DMSO: A Mixed-Competitive Inhibitor of Human Acetylcholinesterase
Kumar A; Darreh-Shori T
Article: SCIENTIFIC REPORTS. 2017;7(1):16287
Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening
Kumar R; Kumar A; Langstrom B; Darreh-Shori T
Article: MATHEMATICAL BIOSCIENCES. 2016;273:70-79
Determination of critical nucleation number for a single nucleation amyloid-β aggregation model
Ghosh P; Vaidya A; Kumar A; Rangachari V
Article: PLOS ONE. 2014;9(11):e111492
Self-Propagative Replication of Aβ Oligomers Suggests Potential Transmissibility in Alzheimer Disease
Kumar A; Pate KM; Moss MA; Dean DN; Rangachari V
Article: ACS CHEMICAL NEUROSCIENCE. 2012;3(11):900-908
The Natural Product Betulinic Acid Rapidly Promotes Amyloid-β Fibril Formation at the Expense of Soluble Oligomers
Planchard MS; Same MA; Kumar A; Rangachari V
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(25):21253-21264
Specific Soluble Oligomers of Amyloid-β Peptide Undergo Replication and Form Non-fibrillar Aggregates in Interfacial Environments
Kumar A; Paslay LC; Lyons D; Morgan SE; Correia JJ; Rangachari V
Article: PLOS ONE. 2011;6(4):e18759
Non-Esterified Fatty Acids Generate Distinct Low-Molecular Weight Amyloid-β (Aβ42) Oligomers along Pathway Different from Fibril Formation
Kumar A; Bullard RL; Patel P; Paslay LC; Singh D; Bienkiewicz EA; Morgan SE; Rangachari V
Article: ACS CHEMICAL NEUROSCIENCE. 2010;1(10):691-701
Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)-Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents
Kumar A; Moody L; Olaivar JF; Lewis NA; Khade RL; Holder AA; Zhang Y; Rangachari V

Alla övriga publikationer

Corrigendum: MOLECULAR PSYCHIATRY. 2024;29(1):38
Discriminative binding of tau PET tracers PI2620, MK6240 and RO948 in Alzheimer's disease, corticobasal degeneration and progressive supranuclear palsy brains [ Nov 10.1038/s41380022-01875-2, 2022]
Malarte M-L; Gillberg P-G; Kumar A; Bogdanovic N; Lemoine L; Nordberg A
Review: CELLS. 2023;12(11):1469
Astrocyte Signature in Alzheimer's Disease Continuum through a Multi-PET Tracer Imaging Perspective
Fontana IC; Scarpa M; Malarte M-L; Rocha FM; Auselle-Bosch S; Bluma M; Bucci M; Chiotis K; Kumar A; Nordberg A
Review: NATURE REVIEWS NEUROLOGY. 2023;19(5):278-288
The role of astrocytic α7 nicotinic acetylcholine receptors in Alzheimer disease
Fontana IC; Kumar A; Nordberg A
Review: JOURNAL OF NEUROCHEMISTRY. 2023;164(3):309-324
Reactive astrogliosis: A friend or foe in the pathogenesis of Alzheimer's disease
Kumar A; Fontana IC; Nordberg A
Review: PLANT BIOLOGY. 2020;22(6):961-970
Plant behaviour: an evolutionary response to the environment?
Kumar A; Memo M; Mastinu A
Review: PLANTA. 2019;249(6):1681-1694
Cannabimimetic plants: are they new cannabinoidergic modulators?
Kumar A; Premoli M; Aria F; Bonini SA; Maccarinelli G; Gianoncelli A; Memo M; Mastinu A
Review: MOLECULES. 2019;24(8):E1517-1517
Zeolite Clinoptilolite: Therapeutic Virtues of an Ancient Mineral
Mastinu A; Kumar A; Maccarinelli G; Bonini SA; Premoli M; Aria F; Gianoncelli A; Memo M
Review: JOURNAL OF ETHNOPHARMACOLOGY. 2018;227:300-315
Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history
Bonini SA; Premoli M; Tambaro S; Kumar A; Maccarinelli G; Memo M; Mastinu A
Published conference paper: BMC BIOINFORMATICS. 2010;11(Suppl 6):S24
Dynamics of protofibril elongation and association involved in Aβ42 peptide aggregation in Alzheimer's disease
Ghosh P; Kumar A; Datta B; Rangachari V

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