Amir Ata Saei

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: BIORXIV. 2024;:2024.03.06.582595
Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules.
Ashkarran AA; Gharibi H; Sadeghi SA; Modaresi SM; Wang Q; Lin T-J; Yerima G; Tamadon A; Sayadi M; Jafari M; Lin Z; Ritz D; Kakhniashvili D; Guha A; Mofrad MRK; Sun L; Landry MP; Saei AA; Mahmoudi M
Journal article: ANALYTICAL CHEMISTRY. 2024;96(33):13533-13541
Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates
Meng Z; Saei AA; Gharibi H; Zhang X; Lyu H; Lundstrom SL; Vegvari A; Gaetani M; Zubarev RA
Journal article: NANO LETTERS. 2024;24(32):9874-9881
Standardizing Protein Corona Characterization in Nanomedicine: A Multicenter Study to Enhance Reproducibility and Data Homogeneity
Ashkarran AA; Gharibi H; Modaresi SM; Saei AA; Mahmoudi M
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2024;35(5):902-911
Adding Color to Mass Spectra of Biopolymers: Charge Determination Analysis (CHARDA) Assigns Charge State to Every Ion Peak
Lyutvinskiy Y; Nagornov KO; Kozhinov AN; Gasilova N; Menin L; Meng Z; Zhang X; Saei AA; Fu T; Chamot-Rooke J; Tsybin YO; Makarov A; Zubarev RA
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2024;7(3):787-796
Chemical Proteomics Reveals that the Anticancer Drug Everolimus Affects the Ubiquitin-Proteasome System
Lobas AA; Saei AA; Lyu H; Zubarev RA; Gorshkov MV
Article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2024;63(3):e202316488
Ultralight Ultrafast Enzymes
Zhang X; Meng Z; Beusch CM; Gharibi H; Cheng Q; Lyu H; Di Stefano L; Wang J; Saei AA; Vegvari A; Gaetani M; Zubarev RA
Article: NATURE COMMUNICATIONS. 2024;15(1):342
A uniform data processing pipeline enables harmonized nanoparticle protein corona analysis across proteomics core facilities
Gharibi H; Ashkarran AA; Jafari M; Voke E; Landry MP; Saei AA; Mahmoudi M
Article: MOLECULES. 2023;28(19):6768
Massive Solubility Changes in Neuronal Proteins upon Simulated Traumatic Brain Injury Reveal the Role of Shockwaves in Irreversible Damage
Saei AA; Gharibi H; Lyu H; Nilsson B; Jafari M; Von Holst H; Zubarev RA
Article: JCI INSIGHT. 2023;8(7):e164875
NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions
Luo H; Urbonaviciute V; Saei AA; Lyu H; Gaetani M; Vegvari A; Li Y; Zubarev RA; Holmdahl R
Article: ACS BIO & MED CHEM AU. 2023;3(1):62-73
Sex-Specific Silica Nanoparticle Protein Corona Compositions Exposed to Male and Female BALB/c Mice Plasmas
Ashkarran AA; Gharibi H; Grunberger JW; Saei AA; Khurana N; Mohammadpour R; Ghandehari H; Mahmoudi M
Article: BIOSENSORS AND BIOELECTRONICS. 2023;220:114862
Multi-omics analysis of magnetically levitated plasma biomolecules
Ashkarran AA; Gharibi H; Abou Zeki D; Radu I; Khalighinejad F; Keyhanian K; Abrahamsson CK; Ionete C; Saei AA; Mahmoudi M
Article: NATURE COMMUNICATIONS. 2022;13(1):6610
Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities
Ashkarran AA; Gharibi H; Voke E; Landry MP; Saei AA; Mahmoudi M
Article: ANALYTICAL CHEMISTRY. 2022;94(43):15048-15056
Proteomics-Compatible Fourier Transform Isotopic Ratio Mass Spectrometry of Polypeptides
Gharibi H; Chernobrovkin AL; Saei AA; Zhang X; Gaetani M; Makarov AA; Zubarev RA
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(15):8371
First Experimental Evidence for Reversibility of Ammonia Loss from Asparagine
Wang J; Rodin S; Saei AA; Zhang X; Zubarev RA
Article: ACS APPLIED BIO MATERIALS. 2022;5(6):2643-2663
Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels
Sharifi S; Saei AA; Gharibi H; Mahmoud NN; Harkins S; Dararatana N; Lisabeth EM; Serpooshan V; Vegvari A; Moore A; Mahmoudi M
Article: ELIFE. 2022;11:e74549
Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation
James J; Chen Y; Hernandez CM; Forster F; Dagnell M; Cheng Q; Saei AA; Gharibi H; Lahore GF; astrand A; Malhotra R; Malissen B; Zubarev RA; Arner ESJ; Holmdahl R
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2022;144(6):2484-2487
Abnormal (Hydroxy)proline Deuterium Content Redefines Hydrogen Chemical Mass
Gharibi H; Chernobrovkin AL; Eriksson G; Saei AA; Timmons Z; Kitchener AC; Kalthoff DC; Liden K; Makarov AA; Zubarev RA
Article: NATURE COMMUNICATIONS. 2021;12(1):6558
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
Sabatier P; Beusch CM; Saei AA; Aoun M; Moruzzi N; Coelho A; Leijten N; Nordenskjold M; Micke P; Maltseva D; Tonevitsky AG; Millischer V; Villaescusa JC; Kadekar S; Gaetani M; Altynbekova K; Kel A; Berggren P-O; Simonson O; Grinnemo K-H; Holmdahl R; Rodin S; Zubarev RA
Article: IRANIAN JOURNAL OF KIDNEY DISEASES. 2021;15(2):121-133
Predictive Biomarker Panel in Proliferative Lupus Nephritis, Two-Dimensional Shotgun
Ghasemi M; Kalantari S; Zubarev RA; Nafar M; Saei AA; Heidari S-S; Baghestani AR; Samavat S
Article: NATURE COMMUNICATIONS. 2021;12(1):1296
System-wide identification and prioritization of enzyme substrates by thermal analysis
Saei AA; Beusch CM; Sabatier P; Wells JA; Gharibi H; Meng Z; Chernobrovkin A; Rodin S; Nareoja K; Thorsell A-G; Karlberg T; Cheng Q; Lundstrom SL; Gaetani M; Vegvari A; Arner ESJ; Schuler H; Zubarev RA
Article: BIOINTERPHASES. 2021;16(1):011008
Can the biomolecular corona induce an allergic reaction?-A proof-of-concept study
Muehe A; Nejadnik H; Muehe H; Rosenberg J; Gharibi H; Saei AA; Lyu S-C; Nadeau KC; Mahmoudi M; Daldrup-Link HE
Article: JOURNAL OF PROTEOME RESEARCH. 2020;19(11):4364-4373
COVID-19: Nanomedicine Uncovers Blood-Clot Mystery
Saei AA; Sharifi S; Mahmoudi M
Article: REDOX BIOLOGY. 2020;32:101491
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin
Saei AA; Gullberg H; Sabatier P; Beusch CM; Johansson K; Lundgren B; Arvidsson PI; Arner ESJ; Zubarev RA
Article: CANCER RESEARCH. 2020;80(7):1538-1550
Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds
Peuget S; Zhu J; Sanz G; Singh M; Gaetani M; Chen X; Shi Y; Saei AA; Visnes T; Lindstrom MS; Rihani A; Moyano-Galceran L; Carlson JW; Hjerpe E; Joneborg U; Lehti K; Hartman J; Helleday T; Zubarev R; Selivanova G
Article: IMMUNOLOGY. 2020;159(1):96-108
Tailoring subtractive cell biopanning to identify diffuse gastric adenocarcinoma-associated antigens via human scFv antibodies
Mehdipour T; Tohidkia MR; Saei AA; Kazemi A; Khajeh S; Rahimi AAR; Nikfarjam S; Farhadi M; Halimi M; Soleimani R; Zubarev RA; Nouri M
Article: NATURE COMMUNICATIONS. 2019;10(1):5715
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
Saei AA; Beusch CM; Chernobrovkin A; Sabatier P; Zhang B; Tokat UG; Stergiou E; Gaetani M; Vegvari A; Zubarev RA
Article: JOURNAL OF PROTEOME RESEARCH. 2019;18(11):4027-4037
Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution
Gaetani M; Sabatier P; Saei AA; Beusch CM; Yang Z; Lundstrom SL; Zubarev RA
Article: BIOCHIMIE. 2019;162:46-54
Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug
Zhang X; Selvaraju K; Saei AA; D'Arcy P; Zubarev RA; Arner ESJ; Linder S
Article: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019;2019:1659468-11
Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment
Zhang X; Espinosa B; Saei AA; D'Arcy P; Zubarev RA; Linder S
Article: CANCER LETTERS. 2019;448:70-83
Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation
Hillert E-K; Brnjic S; Zhang X; Mazurkiewicz M; Saei AA; Mofers A; Selvaraj K; Zubarev R; Linder S; D'Arcy P
Article: PROTEOMICS. 2018;18(24):e1800118
Dynamic Proteomics Reveals High Plasticity of Cellular Proteome: Growth-Related and Drug-Induced Changes in Cancer Cells are Comparable
Sabatier P; Saei AA; Wang S; Zubarev RA
Article: BIOCHEMICAL PHARMACOLOGY. 2018;156:291-301
The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and Check for mitochondrial damage
Zhang X; Pellegrini P; Saei AA; Hillert E-K; Mazurkiewicz M; Olofsson MH; Zubarev RA; D'Arcy P; Linder S
Article: SCIENTIFIC REPORTS. 2018;8(1):12557
Bare surface of gold nanoparticle induces inflammation through unfolding of plasma fibrinogen
Kharazian B; Lohse SE; Ghasemi F; Raoufi M; Saei AA; Hashemi F; Farvadi F; Alimohamadi R; Jalali SA; Shokrgozar MA; Hadipour NL; Ejtehadi MR; Mahmoudi M
Article: JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 2018;46:268-273
Formulation, characterization and cytotoxicity evaluation of ketotifen-loaded nanostructured lipid carriers
Dolatabadi JEN; Azami A; Mohammadi A; Hamishehkar H; Panahi-Azar V; Saadat YR; Saei AA
Article: MOLECULAR & CELLULAR PROTEOMICS. 2018;17(6):1144-1155
Comparative Proteomics of Dying and Surviving Cancer Cells Improves the Identification of Drug Targets and Sheds Light on Cell Life/Death Decisions
Saei AA; Sabatier P; Tokat UG; Chernobrovkin A; Pirmoradian M; Zubarev RA
Article: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. 2017;43(8):1244-1253
Microparticles containing erlotinib-loaded solid lipid nanoparticles for treatment of non-small cell lung cancer
Bakhtiary Z; Barar J; Aghanejad A; Saei AA; Nemati E; Dolatabadi JEN; Omidi Y
Article: COLLOIDS AND SURFACES B: BIOINTERFACES. 2016;143:224-232
Theranostic MUC-1 aptamer targeted gold coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging and photothermal therapy of colon cancer
Azhdarzadeh M; Atyabi F; Saei AA; Varnamkhasti BS; Omidi Y; Fateh M; Ghavami M; Shanehsazzadeh S; Dinarvand R
Article: CURRENT ORGANIC CHEMISTRY. 2015;19(11):982-990
Biomedical Applications of Superparamagnetic Nanoparticles in Molecular Scale
Rahman M; Saei AA; Amiri H; Mahmoudi M
Article: APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. 2014;174(2):667-681
Inhibition of Survivin Restores the Sensitivity of Breast Cancer Cells to Docetaxel and Vinblastine
Ghanbari P; Mohseni M; Tabasinezhad M; Yousefi B; Saei AA; Sharifi S; Rashidi MR; Samadi N
Article: JOURNAL OF NANOPARTICLE RESEARCH. 2014;16(8):2521
Fe₃O₄ nanoparticles engineered for plasmid DNA delivery to Escherichia coli
Saei AA; Barzegari A; Majd MH; Asgari D; Omidi Y
Article: FEMS MICROBIOLOGY LETTERS. 2013;348(1):74-78
Vibration and glycerol-mediated plasmid DNA transformation for Escherichia coli
Shanehbandi D; Saei AA; Zarredar H; Barzegari A
Article: JOURNAL OF MEDICINAL FOOD. 2013;16(2):147-154
Soy Protein, Genistein, and Daidzein Improve Serum Paraoxonase Activity and Lipid Profiles in Rheumatoid Arthritis in Rats
Mohammadshahi M; Haidari F; Saei AA; Rashidi B; Mahboob S; Rashidi M-R
Article: TRAC. TRENDS IN ANALYTICAL CHEMISTRY. 2013;42:216-227
Electrochemical biosensors for glucose based on metal nanoparticles
Saei AA; Najafi-Marandi P; Abhari A; de la Guardia M; Dolatabadi JEN
Article: MOLECULAR BIOLOGY REPORTS. 2012;39(11):9931-9939
Haematococcus as a promising cell factory to produce recombinant pharmaceutical proteins
Saei AA; Ghanbari P; Barzegari A
Article: FUTURE MICROBIOLOGY. 2012;7(9):1037-1046
The microbiome: the forgotten organ of the astronaut's body - probiotics beyond terrestrial limits
Saei AA; Barzegari A
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2012;147(1-3):217-225
Aldehyde and Xanthine Oxidase Activities in Tissues of Streptozotocin-Induced Diabetic Rats: Effects of Vitamin E and Selenium Supplementation
Ghaffari T; Nouri M; Saei AA; Rashidi M-R
Article: FUTURE MICROBIOLOGY. 2012;7(5):571-575
Designing probiotics with respect to the native microbiome
Barzegari A; Saei AA
Article: BIOIMPACTS. 2011;1(3):161-170
Comparison of the effects of genistein and daidzein with dexamethasone and soy protein on rheumatoid arthritis in rats.
Mohammad-Shahi M; Haidari F; Rashidi B; Saei AA; Mahboob S; Rashidi M-R
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2009;(26):1191
Cellular toxicity of nanogenomedicine in MCF-7 cell line: MTT assay.
Ahmadian S; Barar J; Saei AA; Fakhree MAA; Omidi Y
Article: DIE PHARMAZIE. 2008;63(2):113-121
Deviations of drug solubility in water-cosolvent mixtures from the Jouyban-Acree model - effect of solute structure
Jouyban A; Fakhree MAA; Ghafourian T; Saei AA; Acree WEJ
Article: JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 2008;18(2):149-151
Solubility of sodium diclofenac in binary water plus alcohol solvent mixtures at 25°C
Saei AA; Jabbaribar F; Fakhree MAA; Acree WEJ; Jouyban A
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Editorial comment: NANOMEDICINE. 2024;19(14):1223-1226
Multi-omics exploration of biomolecular corona in nanomedicine therapeutics and diagnostics.
Saei AA; Mahmoudi M
Preprint: BIORXIV. 2023
Multifaceted proteome analysis at solubility, redox, and expression dimensions for target identification
Saei AA; Lundin A; Lyu H; Gharibi H; Luo H; Teppo J; Zhang X; Gaetani M; Végvári Á; Holmdahl R; Gygi S; Zubarev R
Preprint: BIORXIV. 2022
Monitoring Functional Post-Translational Modifications Using a Data-Driven Proteome Informatic Pipeline Based on PEIMAN2
Nickchi P; Mirzaie M; Baumann M; Saei AA; Jafari M
Review: CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY. 2022;52(7):1461-1487
Breathomics: Review of Sample Collection and Analysis, Data Modeling and Clinical Applications
Khoubnasabjafari M; Mogaddam MRA; Rahimpour E; Soleymani J; Saei AA; Jouyban A
Preprint: BIORXIV. 2022
Mapping the GALNT1 substrate landscape with versatile proteomics tools
Saei AA; Lundström S; Lyu H; Gharibi H; Lu W; Fang P; Zhang X; Meng Z; Wang J; Gaetani M; Végvári Á; Gygi S; Zubarev R
Preprint: RESEARCH SQUARE. 2021
Ultralight ultrafast enzymes
Zhang X; Meng Z; Beusch C; Gharibi H; Cheng Q; Stefano L; Wang J; Saei A; Vegvari A; Gaetani M; Zubarev R
Review: ADVANCED SCIENCE. 2021;8(21):e2100556
Nanotechnology for Targeted Detection and Removal of Bacteria: Opportunities and Challenges
Hajipour MJ; Saei AA; Walker ED; Conley B; Omidi Y; Lee K-B; Mahmoudi M
Preprint: RESEARCH SQUARE. 2021
SIESTA as a universal unbiased proteomics approach for identification and prioritization of enzyme substrates
Saei AA; Beusch C; Sabatier P; Wells JA; Gharibi H; Meng Z; Chernobrovkin A; Rodin S; Näreoja K; Thorsell A-G; Karlberg T; Cheng Q; Lundström S; Gaetani M; Végvári Á; Arnér ESJ; Schüler H; Zubarev R
Review: JOURNAL OF DRUG TARGETING. 2020;28(10):1018-1033
Immunotargeting and therapy of cancer by advanced multivalence antibody scaffolds
Kafil V; Saei AA; Tohidkia MR; Barar J; Omidi Y
Review: DNA REPAIR. 2019;80:59-84
DNA damage response and repair in ovarian cancer: Potential targets for therapeutic strategies
Mirza-Aghazadeh-Attari M; Ostadian C; Saei AA; Mihanfar A; Darband SG; Sadighparvar S; Kaviani M; Kafil HS; Yousefi B; Majidinia M
Review: DNA REPAIR. 2019;80:8-15
Crosstalk between P53 and DNA damage response in ageing
Mohammadzadeh A; Mirza-Aghazadeh-Attari M; Hallaj S; Saei AA; Alivand MR; Valizadeh A; Yousefi B; Majidinia M
Thesis / dissertation: 2019
Molecular mechanisms and targets of new anticancer treatments
Saei Dibavar, Amirata
Review: CHEMISTRY OF MATERIALS. 2017;29(16):6578-6595
Nanoparticle Surface Functionality Dictates Cellular and Systemic Toxicity
Saei AA; Yazdani M; Lohse SE; Bakhtiary Z; Serpooshan V; Ghavami M; Asadian M; Mashaghi S; Dreaden EC; Mashaghi A; Mahmoudi M
Review: NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY, AND MEDICINE. 2016;12(2):287-307
Targeted superparamagnetic iron oxide nanoparticles for early detection of cancer: Possibilities and challenges
Bakhtiary Z; Saei AA; Hajipour MJ; Raoufi M; Vermesh O; Mahmoudi M
Review: TRENDS IN BIOTECHNOLOGY. 2015;33(12):735-746
Possibilities in Germ Cell Research: An Engineering Insight
Esfandiari F; Mashinchian O; Ashtiani MK; Ghanian MH; Hayashi K; Saei AA; Mahmoudi M; Baharvand H
Review: CONTRAST MEDIA & MOLECULAR IMAGING. 2015;10(5):329-355
Superparamagnetic iron oxide nanoparticles for in vivo molecular and cellular imaging
Sharifi S; Seyednejad H; Laurent S; Atyabi F; Saei AA; Mahmoudi M
Review: NANOMEDICINE. 2015;10(18):2931-2952
Nanotoxicology: advances and pitfalls in research methodology
Azhdarzadeh M; Saei AA; Sharifi S; Hajipour MJ; Alkilany AM; Sharifzadeh M; Ramazani F; Laurent S; Mashaghi A; Mahmoudi M
Review: EXPERT OPINION ON DRUG DELIVERY. 2014;11(9):1449-1470
Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges
Laurent S; Saei AA; Behzadi S; Panahifar A; Mahmoudi M
Review: FUTURE MICROBIOLOGY. 2014;9(5):639-656
Shrinkage of the human core microbiome and a proposal for launching microbiome biobanks
Barzegari A; Saeedi N; Saei AA
Review: JOURNAL OF CANCER RESEARCH AND THERAPEUTICS. 2013;9(4):556-563
Sphingosin 1-phosphate contributes in tumor progression
Tabasinezhad M; Samadi N; Ghanbari P; Mohseni M; Saei AA; Sharifi S; Saeedi N; Pourhassan A

Anställningar

Junior Group Leader, Biozentrum, University of Basel, 2023-
Biträdande Lektor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2024-2029

Examina och utbildning

Medicine Doktorsexamen, Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet, 2019

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