Alexandra Gyllenberg

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Scientific coordinator for the MultipleMS consortium and PROPHET, an EU
funded project at the Institute for Global Public Health

Artiklar

Article: NATURE COMMUNICATIONS. 2024;15(1):6419

A genetic-epigenetic interplay at 1q21.1 locus underlies CHD1L-mediated vulnerability to primary progressive multiple sclerosis

Kakhki MP; Giordano A; Cucuzza CS; Badam TVS; Samudyata S; Lemee MV; Stridh P; Gkogka A; Shchetynsky K; Harroud A; Gyllenberg A; Liu Y; Boddul S; James T; Sorosina M; Filippi M; Esposito F; Wermeling F; Gustafsson M; Casaccia P; Hillert J; Olsson T; Kockum I; Sellgren CM; Golzio C; Kular L; Jagodic M
Article: BRAIN. 2024;:awae110

Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis

Huang J; Tengvall K; Lima IB; Hedstroem AK; Butt J; Brenner N; Gyllenberg A; Stridh P; Khademi M; Ernberg I; Al Nimer F; Manouchehrinia A; Hillert J; Alfredsson L; Andersen O; Sundstroem P; Waterboer T; Olsson T; Kockum I
Article: GENOME MEDICINE. 2020;12(1):18

Towards a European health research and innovation cloud (HRIC)

Aarestrup FM; Albeyatti A; Armitage WJ; Auffray C; Augello L; Balling R; Benhabiles N; Bertolini G; Bjaalie JG; Black M; Blomberg N; Bogaert P; Bubak M; Claerhout B; Clarke L; De Meulder B; D'Errico G; Di Meglio A; Forgo N; Gans-Combe C; Gray AE; Gut I; Gyllenberg A; Hemmrich-Stanisak G; Hjorth L; Ioannidis Y; Jarmalaite S; Kel A; Kherif F; Korbel JO; Larue C; Laszlo M; Maas A; Magalhaes L; Manneh-Vangramberen I; Morley-Fletcher E; Ohmann C; Oksvold P; Oxtoby NP; Perseil I; Pezoulas V; Riess O; Riper H; Roca J; Rosenstiel P; Sabatier P; Sanz F; Tayeb M; Thomassen G; Van Bussel J; Van den Bulcke M; Van Oyen H
Article: NATURE COMMUNICATIONS. 2019;10(1):3081

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

Carlstrom KE; Ewing E; Granqvist M; Gyllenberg A; Aeinehband S; Enoksson SL; Checa A; Badam TVS; Huang J; Gomez-Cabrero D; Gustafsson M; Al Nimer F; Wheelock CE; Kockum I; Olsson T; Jagodic M; Piehl F
Article: GENES AND IMMUNITY. 2017;18(1):48-56

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis

Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Article: GLIA. 2016;64(11):1925-1937

TGFβ Regulates Persistent Neuroinflammation by Controlling Th1 Polarization and ROS Production via Monocyte-Derived Dendritic Cells

Parsa R; Lund H; Tosevski I; Zhang X-M; Malipiero U; Beckervordersandforth J; Merkler D; Prinz M; Gyllenberg A; James T; Warnecke A; Hillert J; Alfredsson L; Kockum I; Olsson T; Fontana A; Suter T; Harris RA
Article: NEURON. 2016;92(2):333-335

NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk

Antel J; Ban M; Baranzini S; Barcellos L; Barizzone N; Beecham A; Berge T; Bernardinelli L; Booth D; Bos S; Buck D; Butkiewicz M; Celius EG; Comabella M; Compston A; Dedham K; Cotsapas C; Alfonso SD; De Jager P; Dubois B; Duquette P; Fontaine B; Gasperi C; Gil E; Goris A; Gourraud PA; Graetz C; Gyllenberg A; Hadjigeorgiou G; Hafler D; Hribko D; Haines J; Harbo H; Hauser S; Warto S; Hawkins C; Hemmer B; Henry R; Hintzen R; Horakova D; Ivinson A; Howard M; Jelcic I; Kaskow B; Kira J-I; Kleinova P; Kockum I; Kucerova K; Lill C; Luessi F; Malhotra S; Martin R; Martinelli F; Matsushita T; McCabe C; McCauley J; Mescheriakkova J; Mitrovic M; Moen S-M; Montalban X; Muhlau M; Nakmura Y; Oksenberg J; Olsson T; Oturai A; Palotie A; Patsopoulos N; Pavlicova J; Pericak-Vance P; Piehl F; Rebeix I; Rioux J; Saarela J; Sawcer S; Sellebjerg F; Sondergaard HB; Sorensen PS; Sospedra M; Spurkland A; Stewart G; Taylor B; Uitterlinden A; Van Duijn C; Zipp F
Article: NEUROLOGY-GENETICS. 2016;2(5):e97

Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk.

Rhead B; Bäärnhielm M; Gianfrancesco M; Mok A; Shao X; Quach H; Shen L; Schaefer C; Link J; Gyllenberg A; Hedström AK; Olsson T; Hillert J; Kockum I; Glymour MM; Alfredsson L; Barcellos LF
Article: GENES AND IMMUNITY. 2014;15(3):162-167

Variability in the CIITA gene interacts with HLA in multiple sclerosis

Gyllenberg A; Piehl F; Alfredsson L; Hillert J; Bomfim IL; Padyukov L; Orho-Melander M; Lindholm E; Landin-Olsson M; Lernmark A; Olsson T; Kockum I
Article: GENES AND IMMUNITY. 2012;13(8):632-640

Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes

Gyllenberg A; Asad S; Piehl F; Swanberg M; Padyukov L; Van Yserloo B; Rutledge EA; McNeney B; Graham J; Orho-Melander M; Lindholm E; Graff C; Forsell C; Akesson K; Landin-Olsson M; Carlsson A; Forsander G; Ivarsson SA; Larsson H; Lindblad B; Ludvigsson J; Marcus C; Lernmark A; Alfredsson L; Akesson K; Olsson T; Kockum I
Article: PLOS ONE. 2012;7(5):e35439

HTR1A a Novel Type 1 Diabetes Susceptibility Gene on Chromosome 5p13-q13

Asad S; Nikamo P; Gyllenberg A; Bennet H; Hansson O; Wierup N; Carlsson A; Forsander G; Ivarsson S-A; Larsson H; Lernmark A; Lindblad B; Ludvigsson J; Marcus C; Ronningen KS; Nerup J; Pociot F; Luthman H; Fex M; Kockum I

Alla övriga publikationer

Preprint: MEDRXIV. 2022

Implication of DNA methylation changes at chromosome 1q21.1 in the brain pathology of Primary Progressive Multiple Sclerosis

Pahlevan Kakhki M; Starvaggi Cucuzza C; Giordano A; Badam T; Strid P; Shchetynsky K; Harroud A; Gyllenberg A; Liu Y; Boddul S; James T; Sorosina M; Filippi M; Esposito F; Wermeling F; Gustafsson M; Casaccia P; Kockum I; Hillert J; Olsson T; Kular L; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):226-227

Implication of DNA methylation changes at chromosome 1q21.1 in the brain pathology of primary progressive multiple sclerosis

Kakhki MP; Cucuzza CS; Gyllenberg A; Badam TVS; Liu Y; Boddul S; James T; Wermeling F; Gustafsson M; Casaccia P; Kockum I; Hillert J; Olsson T; Kular L; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):506-507

Genetic susceptibility to multiple sclerosis is associated with earlier onset and increased disease severity

Huang J; Stridh P; Manouchehrinia A; Gyllenberg A; Alfredsson L; Hillert J; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):233-234

Re-visiting αβ-crystallin: EBNA1 antibody crossreactivity and CRYAB-specific T cell responses in multiple sclerosis

Thomas O; Bronge M; Tengvall K; Gyllenberg A; Hellstrom C; Holmgren E; Graslund T; Khademi M; Martin R; Nilsson P; Gafvelin G; Gronlund H; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):368-369

Methylome and transcriptome analysis implicates nbpf locus in ppms etiopathology

Kakhki MP; Liu Y; Gyllenberg A; Badam TVS; James T; Cucuzza CS; Gustafsson M; Alfredsson L; Hillert J; Olsson T; Casaccia P; Kockum I; Kular L; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:58-59

Utilizing epigenetics to understand mechanisms underlying primary progressive multiple sclerosis

Kakhki MP; Kular L; Liu Y; James T; Gyllenberg A; Alfredsson L; Hillert J; Olsson T; Kockum I; Jagodic M
Corrigendum: GENES AND IMMUNITY. 2017;18(2):109

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis (vol 18, pg 48, 2017)

Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:191

Mendelian randomization provides evidence for a causal effect of low vitamin D on multiple sclerosis risk in two independent populations

Rhead B; Baarnhielm M; Gianfrancesco M; Mok A; Shao X; Quach H; Shen L; Schaefer C; Link J; Gyllenberg A; Hedstrom AK; Olsson T; Hillert J; Kockum I; Glymour MM; Alfredsson L; Barcellos LF
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2015;21:436-437

NOX genes - genetic markers for severe multiple sclerosis?

Gyllenberg A; Olsson LM; Acharjee B; Khademi M; Piehl F; Alfredsson L; Hillert J; Holmdahl R; Olsson T; Kockum I
Thesis / dissertation: 2014

Genetic studies of complex autoimmune disease

Gyllenberg, Alexandra
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2012;76(2):202-203

Age Dependent Variation of Genotypes in MHCII Transactivator Gene (CIITA) in Controls and Association to Type 1 Diabetes

Gyllenberg A; Asad S; Piehl F; Swanberg M; Padyukov L; Van Yserloo B; Rutledge EA; McNeney B; Graham J; Orho-Melander M; Lindholm E; Graff C; Forsell C; Akesson K; Landin-Olsson M; Carlsson A; Forsander G; Ivarsson SA; Larsson H; Lindblad B; Ludvigsson J; Marcus C; Lernmark A; Alfredsson L; Akesson K; Olsson T; Kockum I
Conference publication: DIABETOLOGIA. 2006;49:101-102

Major histocompatibility complex, class H, transactivator, MHC2TA, is associated with type 1 diabetes susceptibility

Ahmed S; Gyllenberg A; Janer M; Rutledge EA; Padyukov L; Graham J; Piehl F; Olsson T; Torn C; Landin-Olsson M; Lernmark A; Kockum I

Forskningsbidrag

Swedish stakeholder mapping and mobilisation for Precision Prevention

VINNOVA

17 October 2022 - 30 June 2023

Anställningar

Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2021-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2014

Om mig

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI