Agnieszka Szwajda

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: NATURE COMMUNICATIONS. 2023;14(1):6172
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Budu-Aggrey A; Kilanowski A; Sobczyk MK; Shringarpure SS; Mitchell R; Reis K; Reigo A; Maegi R; Nelis M; Tanaka N; Brumpton BM; Thomas LF; Sole-Navais P; Flatley C; Espuela-Ortiz A; Herrera-Luis E; Lominchar JVT; Bork-Jensen J; Marenholz I; Arnau-Soler A; Jeong A; Fawcett KA; Baurecht H; Rodriguez E; Alves AC; Kumar A; Sleiman PM; Chang X; Medina-Gomez C; Hu C; Xu C-J; Qi C; El-Heis S; Titcombe P; Antoun E; Fadista J; Wang CA; Thiering E; Wu B; Kress S; Kothalawala DM; Kadalayil L; Duan J; Zhang H; Hadebe S; Hoffmann T; Jorgenson E; Choquet H; Risch N; Njolstad P; Andreassen OA; Johansson S; Almqvist C; Gong T; Ullemar V; Karlsson R; Magnusson PKE; Szwajda A; Burchard EG; Thyssen JP; Hansen T; Karhus LL; Dantoft TM; Jeanrenaud ACSN; Ghauri A; Arnold A; Homuth G; Lau S; Noethen MM; Huebner N; Imboden M; Visconti A; Falchi M; Bataille V; Hysi P; Ballardini N; Boomsma DI; Hottenga JJ; Mueller-Nurasyid M; Ahluwalia TS; Stokholm J; Chawes B; Schoos A-MM; Esplugues A; Bustamante M; Raby B; Arshad S; German C; Esko T; Milani LA; Metspalu A; Terao C; Abuabara K; Loset M; Hveem K; Jacobsson B; Pino-Yanes M; Strachan DP; Grarup N; Linneberg A; Lee Y-A; Probst-Hensch N; Weidinger S; Jarvelin M-R; Melen E; Hakonarson H; Irvine AD; Jarvis D; Nijsten T; Duijts L; Vonk JM; Koppelmann GH; Godfrey KM; Barton SJ; Feenstra B; Pennell CE; Sly PD; Holt PG; Williams LK; Bisgaard H; Bonnelykke K; Curtin J; Simpson A; Murray C; Schikowski T; Bunyavanich S; Weiss ST; Holloway JW; Min JL; Brown SJ; Standl M; Paternoster L
Article: NATURE COMMUNICATIONS. 2021;12(1):6618
Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4
Grosche S; Marenholz I; Esparza-Gordillo J; Arnau-Soler A; Pairo-Castineira E; Rueschendorf F; Ahluwalia TS; Almqvist C; Arnold A; Baurecht H; Bisgaard H; Bonnelykke K; Brown SJ; Bustamante M; Curtin JA; Custovic A; Dharmage SC; Esplugues A; Falchi M; Fernandez-Orth D; Ferreira MAR; Franke A; Gerdes S; Gieger C; Hakonarson H; Holt PG; Homuth G; Hubner N; Hysi PG; Jarvelin M-R; Karlsson R; Koppelman GH; Lau S; Lutz M; Magnusson PKE; Marks GB; Mueller-Nurasyid M; Noethen MM; Paternoster L; Pennell CE; Peters A; Rawlik K; Robertson CF; Rodriguez E; Sebert S; Simpson A; Sleiman PMA; Standl M; Stoelzl D; Strauch K; Szwajda A; Tenesa A; Thompson PJ; Ullemar V; Visconti A; Vonk JM; Wang CA; Weidinger S; Wielscher M; Worth CL; Xu C-J; Lee Y-A
Article: AGE AND AGEING. 2021;50(6):2174-2182
Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?
Bai G; Szwajda A; Wang Y; Li X; Bower H; Karlsson IK; Johansson B; Aslan AKD; Pedersen NL; Hagg S; Jylhava J
Article: BMC PSYCHIATRY. 2021;21(1):369
Taking the LEAP: study protocol for a randomized, multicentre, naturalistic, efficacy trial of the compuLsive Exercise Activity theraPy (LEAP) - a cognitive behavioral program specifically targeting compulsive exercise in patients with eating disorders
Monell E; Meyer C; Szwajda A; Mantilla EF
Article: PLOS GENETICS. 2020;16(6):e1008725
Age-of-onset information helps identify 76 genetic variants associated with allergic disease
Ferreira MAR; Vonk JM; Baurecht H; Marenholz I; Tian C; Hoffman JD; Helmer Q; Tillander A; Ullemar V; Lu Y; Grosche S; Rueschendorf F; Granell R; Brumpton BM; Fritsche LG; Bhatta L; Gabrielsen ME; Nielsen JB; Zhou W; Hveem K; Langhammer A; Holmen OL; Loset M; Abecasis GR; Willer CJ; Emami NC; Cavazos TB; Witte JS; Szwajda A; Hinds DA; Huebner N; Weidinger S; Magnusson PKE; Jorgenson E; Karlsson R; Paternoster L; Boomsma DI; Almqvist C; Lee Y-A; Koppelman GH
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2019;104(4):665-684
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct
Ferreira MAR; Mathur R; Vonk JM; Szwajda A; Brumpton B; Granell R; Brew BK; Ullemar V; Lu Y; Jiang Y; Magnusson PKE; Karlsson R; Hinds DA; Paternoster L; Koppelman GH; Almqvist C
Article: NPJ SYSTEMS BIOLOGY AND APPLICATIONS. 2019;5:20
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer.
Tang J; Gautam P; Gupta A; He L; Timonen S; Akimov Y; Wang W; Szwajda A; Jaiswal A; Turei D; Yadav B; Kankainen M; Saarela J; Saez-Rodriguez J; Wennerberg K; Aittokallio T
Article: MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 2018;10:17-28
Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis
Aldi S; Matic LP; Hamm G; van Keulen D; Tempel D; Holmstrom K; Szwajda A; Nielsen BS; Emilsson V; Ait-Belkacem R; Lengquist M; Paulsson-Berne G; Eriksson P; Lindeman JHN; Gool AJ; Stauber J; Hedin U; Hurt-Camejo E
Article: MOLECULAR CANCER. 2016;15(1):34
Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells.
Gautam P; Karhinen L; Szwajda A; Jha SK; Yadav B; Aittokallio T; Wennerberg K
Article: MOLECULAR & CELLULAR PROTEOMICS. 2015;14(12):3274-3283
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.
Pokharel YR; Saarela J; Szwajda A; Rupp C; Rokka A; Lal Kumar Karna S; Teittinen K; Corthals G; Kallioniemi O; Wennerberg K; Aittokallio T; Westermarck J
Article: DISEASE MODELS & MECHANISMS. 2015;8(10):1255-1264
From drug response profiling to target addiction scoring in cancer cell models.
Yadav B; Gopalacharyulu P; Pemovska T; Khan SA; Szwajda A; Tang J; Wennerberg K; Aittokallio T
Article: DATA IN BRIEF. 2015;4:207-216
Quantitative analysis of PPT1 interactome in human neuroblastoma cells.
Scifo E; Szwajda A; Soliymani R; Pezzini F; Bianchi M; Dapkunas A; Dębski J; Uusi-Rauva K; Dadlez M; Gingras A-C; Tyynelä J; Simonati A; Jalanko A; Baumann MH; Lalowski M
Article: CHEMISTRY AND BIOLOGY. 2015;22(8):1144-1155
Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.
Szwajda A; Gautam P; Karhinen L; Jha SK; Saarela J; Shakyawar S; Turunen L; Yadav B; Tang J; Wennerberg K; Aittokallio T
Article: JOURNAL OF PROTEOMICS. 2015;123:42-53
Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells.
Scifo E; Szwajda A; Soliymani R; Pezzini F; Bianchi M; Dapkunas A; Dębski J; Uusi-Rauva K; Dadlez M; Gingras A-C; Tyynelä J; Simonati A; Jalanko A; Baumann MH; Lalowski M
Article: BRIEFINGS IN BIOINFORMATICS. 2015;16(2):325-337
Toward more realistic drug-target interaction predictions.
Pahikkala T; Airola A; Pietilä S; Shakyawar S; Szwajda A; Tang J; Aittokallio T
Article: MOLECULAR & CELLULAR PROTEOMICS. 2014;13(9):2288-2305
Global analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology.
Zaręba-Kozioł M; Szwajda A; Dadlez M; Wysłouch-Cieszyńska A; Lalowski M
Article: SCIENTIFIC REPORTS. 2014;4:5193
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies.
Yadav B; Pemovska T; Szwajda A; Kulesskiy E; Kontro M; Karjalainen R; Majumder MM; Malani D; Murumägi A; Knowles J; Porkka K; Heckman C; Kallioniemi O; Wennerberg K; Aittokallio T
Article: JOURNAL OF IMMUNOLOGY. 2014;192(10):4551-4559
Naturally Occurring Human Phosphorylcholine Antibodies Are Predominantly Products of Affinity-Matured B Cells in the Adult
Fiskesund R; Steen J; Amara K; Murray F; Szwajda A; Liu A; Douagi I; Malmstrom V; Frostegard J
Article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2014;54(3):735-743
Making sense of large-scale kinase inhibitor bioactivity data sets: a comparative and integrative analysis.
Tang J; Szwajda A; Shakyawar S; Xu T; Hintsanen P; Wennerberg K; Aittokallio T
Article: CANCER DISCOVERY. 2013;3(12):1416-1429
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.
Pemovska T; Kontro M; Yadav B; Edgren H; Eldfors S; Szwajda A; Almusa H; Bespalov MM; Ellonen P; Elonen E; Gjertsen BT; Karjalainen R; Kulesskiy E; Lagström S; Lehto A; Lepistö M; Lundán T; Majumder MM; Marti JML; Mattila P; Murumägi A; Mustjoki S; Palva A; Parsons A; Pirttinen T; Rämet ME; Suvela M; Turunen L; Västrik I; Wolf M; Knowles J; Aittokallio T; Heckman CA; Porkka K; Kallioniemi O; Wennerberg K
Journal article: BLOOD. 2013;122(21):482
Identification Of AML Subtype-Selective Drugs By Functional Ex Vivo Drug Sensitivity and Resistance Testing and Genomic Profiling
Pemovska T; Kontro M; Yadav B; Edgren H; Eldfors S; Szwajda A; Almusa H; Bespalov M; Ellonen P; Elonen E; Gjertsen BT; Karjalainen R; Kulesskiy E; Lagström S; Lehto A; Lepistö M; Lundan T; Majumder MM; Marti JML; Mattila P; Murumägi A; Mustjoki S; Palva A; Parsons A; Pirttinen T; Rämet ME; Suvela M; Turunen L; Västrik I; Wolf M; Knowles J; Aittokallio T; Heckman CA; Porkka K; Kallioniemi O; Wennerberg K
Article: CANCER RESEARCH. 2013;73(22):6757-6769
Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells.
Khanna A; Kauko O; Böckelman C; Laine A; Schreck I; Partanen JI; Szwajda A; Bormann S; Bilgen T; Helenius M; Pokharel YR; Pimanda J; Russel MR; Haglund C; Cole KA; Klefström J; Aittokallio T; Weiss C; Ristimäki A; Visakorpi T; Westermarck J
Article: JOURNAL OF PROTEOME RESEARCH. 2013;12(5):2101-2115
Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.
Scifo E; Szwajda A; Dębski J; Uusi-Rauva K; Kesti T; Dadlez M; Gingras A-C; Tyynelä J; Baumann MH; Jalanko A; Lalowski M
Article: PLOS COMPUTATIONAL BIOLOGY. 2013;9(9):e1003226
Target inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathways.
Tang J; Karhinen L; Xu T; Szwajda A; Yadav B; Wennerberg K; Aittokallio T
Journal article: BLOOD. 2012;120(21):288
High-Throughput Ex Vivo Drug Sensitivity and Resistance Testing (DSRT) Integrated with Deep Genomic and Molecular Profiling Reveal New Therapy Options with Targeted Drugs in Subgroups of Relapsed Chemorefractory AML
Heckman CA; Kontro M; Pemovska T; Eldfors S; Edgren H; Kulesskiy E; Majumder MM; Karjalainen R; Yadav B; Szwajda A; Venkata NPK; Murumägi A; Malani D; Parsons A; Hintsanen P; Almusa H; Martí JML; Ellonen P; Mattila P; Lepistö M; Lagström S; Suvela M; Mustjoki S; Saarela J; Aittokallio T; Kallioniemi O; Wennerberg K; Porkka K
Journal article: CANCER RESEARCH. 2012;72(8_Supplement):895
Abstract 895: Quantitative drug sensitivity and resistance testing (DSRT) of primary ex vivo AML blasts highlights mTOR and MEK as potential key molecular driver signals of therapeutic significance
Pemovska T; Kylesskiy E; Kontro M; Szwajda A; Karjalainen R; Majumder MM; Malani D; Bespalov MM; Eldfors S; Elonen E; Knowles J; Murumägi A; Mpindi JP; Edgren H; Venkata NPK; Turunen L; Mustjoki S; Wolf M; Yadav B; Aittokallio T; Heckman CA; Porkka K; Kallioniemi O; Wennerberg K
Journal article: CANCER RESEARCH. 2012;72(8_Supplement):3188
Abstract 3188: Development of a cancer pharmacopeia-wide ex-vivo drug sensitivity and resistance testing (DSRT) platform for AML: Towards individually optimized therapy and improved understanding of drug resistance patterns
Malani D; Pemovska T; Kontro M; Murumägi A; Kulesskiy E; Yadav B; Bespalov M; Eldfors S; Elonen E; Karjalainen R; Knowles JK; Majumder MM; Mpindi JP; Edgren H; Szwajda A; Venkata NPK; Turunen L; Mustjoki S; Wolf M; Aittokallio T; Heckman CA; Porkka K; Wennerberg K; Kallioniemi O
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