This page in English
Laddar profil information

Om mig

Läkare och forskare inom systembiologi och människans immunsystem med särskilt intresse för immunsystemets utveckling hos nyfödda barn.

Lär mer på min engelska profilsida.


Automated Cell Processing for Mass Cytometry Experiments
Mikes J, Olin A, Lakshmikanth T, Chen Y, Brodin P
Methods in molecular biology (Clifton, N.J.) 2019;1989():111-123

B cell alterations during BAFF inhibition with belimumab in SLE
Ramsköld D, Parodis I, Lakshmikanth T, Sippl N, Khademi M, Chen Y, et al
EBioMedicine 2019;40():517-527

B cell profiling in malaria reveals expansion and remodelling of CD11c+ B cell subsets
Sundling C, Rönnberg C, Yman V, Asghar M, Jahnmatz P, Lakshmikanth T, et al
JCI insight 2019;5():-

Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis
Tang Q, Ramsköld D, Krystufkova O, Mann Hf, Wick C, Dastmalchi M, et al
Scandinavian journal of immunology 2019;89(1):e12732-

Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants
Lundgren P, Klevebro S, Brodin P, Smith Leh, Hallberg B, Hellström A
Acta paediatrica (Oslo, Norway : 1992) 2019;():-

Mass cytometry identifies distinct CD4+ T cell clusters distinguishing HIV-1-infected patients according to antiretroviral therapy initiation
Bekele Y, Lakshmikanth T, Chen Y, Mikes J, Nasi A, Petkov S, et al
JCI insight 2019;4(3):-

Systems-Level Immune Monitoring by Mass Cytometry
Lakshmikanth T, Brodin P
Methods in molecular biology (Clifton, N.J.) 2019;1913():33-48

Systems-level patterns emerge
Brodin P
Nature reviews. Immunology 2019;19(2):87-88

The biology of the cell - insights from mass cytometry
Brodin P
The FEBS journal 2019;286(8):1514-1522

The repertoire of maternal anti-viral antibodies in human newborns
Pou C, Nkulikiyimfura D, Henckel E, Olin A, Lakshmikanth T, Mikes J, et al
Nature medicine 2019;25(4):591-596

Continuous Immune Cell Differentiation Inferred From Single-Cell Measurements Following Allogeneic Stem Cell Transplantation
Chen Y, Lakshmikanth T, Olin A, Mikes J, Remberger M, Brodin P
Frontiers in molecular biosciences 2018;5():81-

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
Agudelo Lz, Ferreira Dms, Cervenka I, Bryzgalova G, Dadvar S, Jannig Pr, et al
Cell metabolism 2018;27(2):378-392.e5

Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains
Ju Ch, Blum Lk, Kongpachith S, Lingampalli N, Mao R, Brodin P, et al
Clinical immunology (Orlando, Fla.) 2018;193():70-79

Rebooting Human Immunology
Davis Mm, Brodin P
Annual review of immunology 2018;36():843-864

Stereotypic Immune System Development in Newborn Children
Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, et al
Cell 2018;174(5):1277-1292.e14

Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease
Stikvoort A, Chen Y, Rådestad E, Törlén J, Lakshmikanth T, Björklund A, et al
Frontiers in immunology 2017;8():717-

Continuous immunotypes describe human immune variation and predict diverse responses
Kaczorowski Kj, Shekhar K, Nkulikiyimfura D, Dekker Cl, Maecker H, Davis Mm, et al
Proceedings of the National Academy of Sciences of the United States of America 2017;114(30):E6097-E6106

Expression of CD226 is associated to but not required for NK cell education
Wagner Ak, Kadri N, Snäll J, Brodin P, Gilfillan S, Colonna M, et al
Nature communications 2017;8():15627-

Human immune system variation
Brodin P, Davis Mm
Nature reviews. Immunology 2017;17(1):21-29

Life-Saving Degeneracy in the Human Immune System
Brodin P
Cell host & microbe 2017;21(3):309-310

Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation
Lakshmikanth T, Olin A, Chen Y, Mikes J, Fredlund E, Remberger M, et al
Cell reports 2017;20(9):2238-2250

Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis
Kaiser Y, Lakshmikanth T, Chen Y, Mikes J, Eklund A, Brodin P, et al
Frontiers in immunology 2017;8():1130-

The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education
Ganesan S, Luu Tt, Chambers Bj, Meinke S, Brodin P, Vivier E, et al
Scandinavian journal of immunology 2017;86(3):135-142

Immune Adaptation to Environmental Influence: The Case of NK Cells and HCMV
Rölle A, Brodin P
Trends in immunology 2016;37(3):233-243

Powerful Populations Respond to Viruses and Vaccines
Brodin P
Immunity 2015;43(6):1035-7

Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy
Nakasone H, Remberger M, Tian L, Brodin P, Sahaf B, Wu F, et al
Haematologica 2015;100(11):1477-85

Variation in the human immune system is largely driven by non-heritable influences
Brodin P, Jojic V, Gao T, Bhattacharya S, Angel Cj, Furman D, et al
Cell 2015;160(1-2):37-47

Automatic Classification of Cellular Expression by Nonlinear Stochastic Embedding (ACCENSE)
Shekhar K, Brodin P, Davis Mm, Chakraborty Ak
Proceedings of the National Academy of Sciences of the United States of America 2014;111(1):202-7

Natural killer cell inhibitory receptor expression in humans and mice: a closer look
Sternberg-simon M, Brodin P, Pickman Y, Onfelt B, Kärre K, Malmberg Kj, et al
Frontiers in immunology 2013;4():65-

Systems level immune response analysis and personalized medicine
Brodin P, Valentini D, Uhlin M, Mattsson J, Zumla A, Maeurer Mj
Expert review of clinical immunology 2013;9(4):307-17

Major surgery in a neutropenic patient undergoing allogeneic stem cell transplantation for high risk myelofibrosis
Brodin P, Gilg S, Lundell L, Mattsson J
International journal of hematology 2012;96(6):798-800

MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma
Sonkoly E, Lovén J, Xu N, Meisgen F, Wei T, Brodin P, et al
Oncogenesis 2012;1():e3-

Skewing of the NK Cell Repertoire by MHC Class I via Quantitatively Controlled Enrichment and Contraction of Specific Ly49 Subsets
Brodin P, Lakshmikanth T, Karre K, Hoglund P
JOURNAL OF IMMUNOLOGY 2012;188(5):2218-26

MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2
Xu N, Brodin P, Wei Tl, Meisgen F, Eidsmo L, Nagy N, et al

Current perspectives of natural killer cell education by MHC class I molecules
Hoglund P, Brodin P

MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma
Loven J, Zinin N, Wahlstrom T, Muller I, Brodin P, Fredlund E, et al

Natural Killer Cell Tolerance Persists Despite Significant Reduction of Self MHC Class I on Normal Target Cells in Mice
Brodin P, Lakshmikanth T, Mehr R, Johansson Mh, Duru Ad, Achour A, et al
PLOS ONE 2010;5(10):-

The role of human microRNA-125b in psoriasis
Xu N, Brodin P, Wei Tl, Meisgen F, Eidsmo L, Stahle M, et al

A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHIC Class I for Natural Killer Cell Education
Chalifour A, Scarpellino L, Back J, Brodin P, Devevre E, Gros F, et al
IMMUNITY 2009;30(3):337-47

Classical Major Histocompatibility Complex Class I Molecules in Motoneurons: New Actors at the Neuromuscular Junction
Thams S, Brodin P, Plantman S, Saxelin R, Karre K, Cullheim S
JOURNAL OF NEUROSCIENCE 2009;29(43):13503-15

Distinct and Overlapping Patterns of Cytokine Regulation of Thymic and Bone Marrow-Derived NK Cell Development
Cheng M, Charoudeh Hn, Brodin P, Tang Yj, Lakshmikanth T, Hoglund P, et al
JOURNAL OF IMMUNOLOGY 2009;182(3):1460-8

NK cell education: not an on-off switch but a tunable rheostat
Brodin P, Karre K, Hoglund P
TRENDS IN IMMUNOLOGY 2009;30(4):143-9

Probing Natural Killer Cell Education by Ly49 Receptor Expression Analysis and Computational Modelling in Single MHC Class I Mice
Johansson S, Salmon-divon M, Johansson Mh, Pickman Y, Brodin P, Karre K, et al
PLOS ONE 2009;4(6):e6046-

The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells
Brodin P, Lakshmikanth T, Johansson S, Karre K, Hoglund P
BLOOD 2009;113(11):2434-41

Beyond licensing and disarming: a quantitative view on NK-cell education
Brodin P, Höglund P
European journal of immunology 2008;38(11):2934-7

Critical role of Qa1(b) in the protection of mature dendritic cells from NK cell-mediated killing
Persson Cm, Assarsson E, Vahlne G, Brodin P, Chambers Bj

IFN-gamma production and degranulation are differentially regulated in response to stimulation in murine natural killer cells
Vahlne G, Becker S, Brodin P, Johansson Mh

Visa alla publikationer