Tissue, Stem Cell and Genetic model core facilities

The Karolinska ATMP Center has been established by Karolinska Institutet and Karolinska University Hospital to further advance cell, gene and tissue therapies. The Karolinska ATMP Center is unique and leading in Europe as all parts of ATMP are under one roof: research, development, production and treatment.

KISCO is a facility at the Department of Biosciences and Nutrition (BioNut), Campus Flemingsberg.

The main goal of KISCO is, to assist researchers mainly within KI and Sweden to harbour the potential of pluripotent stem cells (PSCs) in studying complex human disease mechanisms.

CFG offers massively parallel genetic perturbations and genetic screening for unbiased discovery. Examples of our toolbox include genome-wide or custom CRISPR-based loss- and gain-of-function screens, small screens coupled with single cell transcriptomics as a readout, base-editing tiling mutagenesis screens and other modalities.