Spotlight on Childhood Cancer
These days, the lives of many children diagnosed with cancer can be saved, but the treatment can lead to problems later in life. Researchers at Karolinska Institutet are working to find new and better treatments for childhood cancers, as well as to improve life quality for those who survive.
Survival at a reasonable price
Four out of five children diagnosed with cancer survive. But many survivors suffer side effects of their cancer treatment later in life. Where previously the aim was to survive at all costs, the aim is now increasingly to survive at a reasonable price.
Childhood cancer genetics
These days we know of about 100 genes that we are certain are significant, but in the vast majority of cases we don’t know why children develop cancer.
Cancer drugs for children
Thanks to a new approach to developing new cancer drugs for children the hope is growing of saving more.
Lithium can reverse radiation damage
The drug lithium can help reverse the damage caused by radiotherapy for a brain tumour. Researchers at KI are now planning to test the treatment in clinical trials.
Anti-depressant repurposed to treat childhood cancer
A new study has found that a commonly prescribed anti-depressant may halt growth of a type of cancer known as childhood sarcoma, at least in mice and laboratory cell experiments.
William Florin: “There was no other option than to get well”
William Florin was 15 years old when he had cancer of the nasopharynx. It affects one teenager every three years.
Stina Abrahamsson: “Elsa and me were like one person”
"That morning we had been out picking spring flowers, and now we had been told that our one-year-old had leukaemia."
Freja Östergren Löthén: “I get annoyed when people say I seem strong”
Freja Östergren Löthén wants to be a paediatric oncologist. She thinks children would find it reassuring if their doctor was someone who had had the same experience.
Some of our researchers in this area
Searching for better neuroblastoma treatments
Per Kogner is a senior physician and Professor of Paediatric Oncology. He is among other things occupied with trying to find better medications for neuroblastoma, an aggressive form of childhood cancer.
Studies injury and repair in the developing brain
Klas Blomgren is a paediatric oncologist and Professor of Paediatrics. His research is focused on injury and repair in the developing brain, with the aim to minimise the effects of an injury and promote mechanisms of repair.
Focus on clinical ethics in paediatric cancer care
Pernilla Pergert is Associate Professor and Principal Investigator of the Childhood Cancer Healthcare Research Group. Her research focus is intercultural care and clinical ethics in paediatric cancer care.
Epigenetics and stem cells in childhood cancers
Ola Hermanson is a Professor of Neuroscience and studies transcriptional and epigenetic regulation of tumor cell and cancer-derived stem cell state and fate, especially in glioma and childhood cancers medulloblastoma and neuroblastoma.