Publications 2020

Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.
Appelberg S, Gupta S, Svensson Akusjärvi S, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, Krishnan S, Singh K, Penninger JM, Mirazimi A, Neogi U
Emerg Microbes Infect 2020 Dec;9(1):1748-1760

Differentiation of ciliated human midbrain-derived LUHMES neurons.
Lauter G, Coschiera A, Yoshihara M, Sugiaman-Trapman D, Ezer S, Sethurathinam S, Katayama S, Kere J, Swoboda P
J Cell Sci 2020 11;133(21)::

Human ex vivo spinal cord slice culture as a useful model of neural development, lesion, and allogeneic neural cell therapy.
Lin C, Calzarossa C, Fernandez-Zafra T, Liu J, Li X, Ekblad-Nordberg Å, Vazquez-Juarez E, Codeluppi S, Holmberg L, Lindskog M, Uhlén P, Åkesson E
Stem Cell Res Ther 2020 07;11(1):320

Targeting RAS-converting enzyme 1 overcomes senescence and improves progeria-like phenotypes of ZMPSTE24 deficiency.
Yao H, Chen X, Kashif M, Wang T, Ibrahim MX, Tüksammel E, Revêchon G, Eriksson M, Wiel C, Bergo MO
Aging Cell 2020 08;19(8):e13200

Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs.
Rao A, Strauss O, Kokkinou E, Bruchard M, Tripathi KP, Schlums H, Carrasco A, Mazzurana L, Konya V, Villablanca EJ, Björkström NK, Lindforss U, Spits H, Mjösberg J
Nat Commun 2020 04;11(1):2049

Preclinical safety studies of human embryonic stem cell-derived retinal pigment epithelial cells for the treatment of age-related macular degeneration.
Petrus-Reurer S, Kumar P, Padrell Sánchez S, Aronsson M, André H, Bartuma H, Plaza Reyes A, Nandrot EF, Kvanta A, Lanner F
Stem Cells Transl Med 2020 08;9(8):936-953

Alternative UNC13D Promoter Encodes a Functional Munc13-4 Isoform Predominantly Expressed in Lymphocytes and Platelets.
Galgano D, Soheili T, Voss M, Torralba-Raga L, Tesi B, Cichocki F, Andre I, Rettig J, Cavazzana M, Bryceson Y
Front Immunol 2020 ;11():1154

Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II.
Petrus-Reurer S, Winblad N, Kumar P, Gorchs L, Chrobok M, Wagner AK, Bartuma H, Lardner E, Aronsson M, Plaza Reyes Á, André H, Alici E, Kaipe H, Kvanta A, Lanner F
Stem Cell Reports 2020 04;14(4):648-662

Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells.
Plaza Reyes A, Petrus-Reurer S, Padrell Sánchez S, Kumar P, Douagi I, Bartuma H, Aronsson M, Westman S, Lardner E, André H, Falk A, Nandrot EF, Kvanta A, Lanner F
Nat Commun 2020 03;11(1):1609

Coordinated hedgehog signaling induces new hair follicles in adult skin.
Sun X, Are A, Annusver K, Sivan U, Jacob T, Dalessandri T, Joost S, Füllgrabe A, Gerling M, Kasper M
Elife 2020 03;9():

Ventral prostate and mammary gland phenotype in mice with complete deletion of the ERβ gene.
Warner M, Wu WF, Montanholi L, Nalvarte I, Antonson P, Gustafsson JA
Proc Natl Acad Sci U S A 2020 03;117(9):4902-4909

A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes.
Elvarsdóttir EM, Mortera-Blanco T, Dimitriou M, Bouderlique T, Jansson M, Hofman IJF, Conte S, Karimi M, Sander B, Douagi I, Woll PS, Hellström-Lindberg E
Leukemia 2020 01;34(1):271-282

Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells.
Wagner M, Yoshihara M, Douagi I, Damdimopoulos A, Panula S, Petropoulos S, Lu H, Pettersson K, Palm K, Katayama S, Hovatta O, Kere J, Lanner F, Damdimopoulou P
Nat Commun 2020 03;11(1):1147

The Molecular Anatomy of Mouse Skin during Hair Growth and Rest.
Joost S, Annusver K, Jacob T, Sun X, Dalessandri T, Sivan U, Sequeira I, Sandberg R, Kasper M
Cell Stem Cell 2020 03;26(3):441-457.e7