Publications 2019

A list of LCI related publications from 2019.

A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.
Asp M, Giacomello S, Larsson L, Wu C, Fürth D, Qian X, et al
Cell 2019 Dec;179(7):1647-1660.e19

Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation.
Gerenu G, Persson T, Goikolea J, Calvo-Garrido J, Loera-Valencia R, Pottmeier P, et al
Mol. Psychiatry 2019 Sep;():

Normal mammary gland development after MMTV-Cre mediated conditional PAK4 gene depletion.
Rabieifar P, Zhuang T, Costa TDF, Zhao M, Strömblad S
Sci Rep 2019 Oct;9(1):14436

Human induced pluripotent stem cells from two azoospermic patients with Klinefelter syndrome show similar X chromosome inactivation behavior to female pluripotent stem cells.
Panula S, Kurek M, Kumar P, Albalushi H, Padrell Sánchez S, Damdimopoulou P, et al
Hum. Reprod. 2019 Nov;34(11):2297-2310

A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes.
Elvarsdóttir EM, Mortera-Blanco T, Dimitriou M, Bouderlique T, Jansson M, Hofman IJF, et al
Leukemia 2020 Jan;34(1):271-282

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.
Costa TDF, Zhuang T, Lorent J, Turco E, Olofsson H, Masia-Balague M, et al
Nat Commun 2019 08;10(1):3589

Pleomorphic Adenoma Gene 1 Is Needed For Timely Zygotic Genome Activation and Early Embryo Development.
Madissoon E, Damdimopoulos A, Katayama S, Krjutškov K, Einarsdottir E, Mamia K, et al
Sci Rep 2019 Jun;9(1):8411

Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins.
Sola-Carvajal A, Revêchon G, Helgadottir HT, Whisenant D, Hagblom R, Döhla J, et al
J. Invest. Dermatol. 2019 Nov;139(11):2272-2280.e12

SQSTM1/p62-Directed Metabolic Reprogramming Is Essential for Normal Neurodifferentiation.
Calvo-Garrido J, Maffezzini C, Schober FA, Clemente P, Uhlin E, Kele M, et al
Stem Cell Reports 2019 04;12(4):696-711

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation.
Guerrero-Gómez D, Mora-Lorca JA, Sáenz-Narciso B, Naranjo-Galindo FJ, Muñoz-Lobato F, Parrado-Fernández C, et al
Cell Death Differ. 2019 Sep;26(9):1545-1565