Department of Oncology-Pathology
The Department of Oncology-Pathology conducts basic, translational and clinical research and educational activities related to cancer.
Lars Holmgren on twitter
Lars Holmgren on twitter
Follow the chair of the department of Oncology-Pathology Lars Holmgren on twitter.
Discovery of novel prognosis-associated lung cancer cell subsets
Discovery of novel prognosis-associated lung cancer cell subsets
Arne Östman and group members, with partners at Uppsala University and FIMM/Helsinki University, have published in Journal of the National Cancer Institute their discovery of novel prognosis-associated fibroblast subsets in non-small cell lung cancer (NSCLC).
The study analyzed more than 600 cases of NSCLC, using novel methods for multiplex staining and digital image analyses. Two different fibroblast types were identified, associated with good and bad prognosis, respectively. These subsets also showed different associations with driver mutations and immune features suggesting new mechanisms for the interplay between malignant cells, fibroblasts and immune cells. Upcoming studies will analyze these mechanisms and the ability of the fibroblast subsets to act as treatment-predictive biomarkers.
Lukas Orre - new docent
Lukas Orre - new docent
Lukas Orre at the Department of Oncology-Pathology has become docent in experimental oncology.
Xiaofei Ye receives the Dan Grandér Memorial Prize for best thesis 2021
Xiaofei Ye receives the Dan Grandér Memorial Prize for best thesis 2021
The 2021 Dan Grandér Prize for best thesis at Karolinska Institutet within the field of cancer research is awarded to Xiaofei Ye for translating sequencing data into an understanding of disease mechanisms that potentially may lead to better diagnosis and treatment of lymphoma.
Xiaofei Ye will present his research at “Frontiers in Cancer Research and Therapy” conference at BioClinicum on 30 September 2022.
Stefan Einhorn awarded the 2022 Grand Silver Medal
Stefan Einhorn awarded the 2022 Grand Silver Medal
This year’s Grand Silver Medals are awarded to Jan Andersson, Stefan Einhorn and Ingrid Lundberg. The medal recognises excellence in support of Karolinska Institutet and is awarded during the installation ceremony in Aula Medica on October 13.
Three researchers at OnkPat receives funding from the Swedish Cancer Society
Linda Sofie Lindström receives the Senior investigator award for her research project entitled ”Identification of late risk mechanisms for fatal breast cancer disease”, Lotta Hansson receives the Senior Clinical Investigator Award for her projekt entitled ”Cronic lymfocytic leukemia (CLL): real world effects of precision medicine and clinical/immunological studies in CLL patients post Covid-19 infection and vaccination.” Eva Onjukka receives the Fellowship within radiotherapy research for her project ”Real world-data för evidensbaserad stråldosplanering vid huvud/halscancer.”
The cancer researcher who fled from the war in Ukraine
Viktoriya Tsuber fled from Ukraine and her hometown Poltava just when the war started. Just a few days after her flight via Poland, she started working as a researcher at Karolinska Institutet in Professor Thomas Helledays lab at the department of Oncology-Pathology.
A new digital tool for an efficient implementation of individualized cancer treatment
A new digital tool for an efficient implementation of individualized cancer treatment
David Tamborero and Janne Lehtiö at OnkPat together with colleagues around Europe has published an article in Nature Cancer. There they describe The Molecular Tumor Board Portal which is a system that identifies the specific genomic alterations that are driving a patient's tumor and associate these results with available anti-cancer therapies. This system can allow the use of new technologies and emerging biomarkers that can further improve the selection of the most appropriate treatment for each patient.
SAVE THE DATE
16th of November 2022: ”En dag för cancerforskning, Karolinska Institutet” takes place on the 16th of November 2022.
16th of November 2022: ”En dag för cancerforskning, Karolinska Institutet” takes place on the 16th of November 2022.
During this day researchers talk about their groundbreaking cancer research. Check out the program from last year and look out for more information.
Registration opens in August!
16-17th of May 2023: 6th Cancer Swedish Research Meeting
16-17th of May 2023: 6th Cancer Swedish Research Meeting
The meeting is open to all clinical, preclinical researchers and others with an interest in cancer research from the organizing universities.
Venue: Karolinska Institutet, Aula Medica, Erling Persson-salen, Nobels väg 6, 171 65 Solna
Host: Cancer Research KI
Organizers: U-CAN from Uppsala/Umeå Universities, LUCC (Lund University Cancer Centre), University of Gothenburg, and Cancer Research KI from Karolinska Institutet.