Department of Oncology-Pathology
The Department of Oncology-Pathology conducts basic, translational and clinical research and educational activities related to cancer.
Selective regulation of mRNA translation regulates the tumor associated macrophages immunesupressive phenotype
Charlotte Rolny’s and Ola Larsson’s research teams at the Department of Oncology-Pathology has published an article in PNAS.
New top publication from Martin Enge
New top publication from Martin Enge
Martin Enge’s research group at the department of Oncology-Pathology has developed a new method for joint analysis of a cell’s state and accumulated genetic variation in single cells, applied to childhood leukemias and other cancers. The article is published in the journal Molecular Cell, October 16th.
Funding from Cancer Research KI to OnkPat researchers
Martin Enge, Marzia Palma and Theodoros Foukakis has received "Translational Seed Funding Grant" from Cancer Research KI. Theodoros Foukakis has also received funding for his project in breast cancer through the joint funding KI-Mayo Clinic Cancer Center.
Women could conceive after ovarian tumours
Women could conceive after ovarian tumours
Women receiving fertility-sparing surgery for treatment of borderline ovarian tumours were able to have children, a study from Karolinska Institutet in Sweden led by Kenny Rodriguez-Wallberg published in Fertility & Sterility shows. Natural fertility was preserved in most of them and only a small proportion required assisted reproductive treatment such as in vitro fertilization. Survival in the group was also as high as in women who had undergone radical surgery for treatment of similar tumours.
Unique global online tool paves the way for more individualised cancer treatments
Professor Janne Lehtiö and researcher David Tamborero at OnkPat has published an article in Nature Medicine regarding a new online tool, the Molecular Tumor Board (MTB) portal. The MTB portal makes it possible to match the specific properties of one tumour with various approved or experimental treatments tested in clinical trials.
New publication in Human Reproduction
New publication in Human Reproduction
A multicenter study including all women with breast cancer undergoing treatment for fertility preservation in Sweden revealed efficacy and safety of the procedures.
New top publication in Science Advances
New top publication in Science Advances
A novel autophagy inhibitor from Sprint Bioscience developed in collaboration with OnkPat improves the efficacy of immunotherapy in preclinical tumor models.
Two OnkPat employments financed via the Swedish Cancer Society
Two OnkPat employments financed via the Swedish Cancer Society
Senior Clinical Investigator Award goes to Kenny Rodriguez-Wallberg and Junior Clinical Investigator Award goes to Hildur Helgadottir, both at OnkPat.