Department of Oncology-Pathology
The Department of Oncology-Pathology conducts basic, translational and clinical research and educational activities related to cancer.
Smaller operational margins just as safe in high-risk melanoma
Smaller operational margins just as safe in high-risk melanoma
Hanna Eriksson and Deborah Utjés from OnkPat have in a multicenter study shown that it is enough with two centimeter margin at surgery for malignant melanoma instead of up to four centimeters which has been used. In the study, published in The Lancet, the researchers has followed over 900 patients for an average span of 19 years.
Prognostic importance of PDL-1 in breast cancer
Theodoros Foukakis with colleagues in Belgium and OnkPat has compiled an analysis of the immuno-checkpoint protein PDL-1 (a target for immunotherapy) and shown that it can predict the prognosis for breast cancer. The results have been published in Clinical Cancer Research.
Effect of vaccination against Human Papillomavirus
Effect of vaccination against Human Papillomavirus
Tina Dalianis at OnkPat has together with colleagues in the HPV Vaccination Impact Group published an article in Lancet where they studied the effect of vaccination of girls and women against Human Papillomavirus (HPV). They could see that vaccination had a significant impact on HPV infection, genital warts and malignant cell changes in girls, women, boys and men.
High impact publication in Lancet Oncology
Hanna Eriksson and Johan Hansson with colleagues in the Netherlands have published an article in Lancet Oncology where they show that it is better to give neoadjuvant immunotherapy to cancer patients before the surgeon removes a tumor instead of afterwards.
Two assistant professorships sponsored by the Swedish Childhood Cancer Fund
Monika Ehnman and Nina Gustafsson Sheppard were granted funding for four years assistant professorships from the Swedish Childhood Cancer Fund.
Grants from Dr Åke Olsson Foundation for Hematological Research 2019
This year four researchers from the Department of Oncology-Pathology will share a grant of 2 000 000 SEK: Isabelle Magalhaes, Jeanette Lundin, Nina Gustafsson Sheppard and Mohammad Hojjat Farsangi.
Two high impact articles from Arne Östman
Elin Sjöberg and Carina Strell, in the group of Arne Östman have published two articles in high impact journals. One of them in Clinical Cancer Research and the other one in Journal of the National Cancer Institute. Both articles deals with fibroblasts and their role in breast cancer.
Proteome picture of breast cancer
In a new study, led by professor Janne Lehtiö (SciLifeLab, Karolinska Institutet), researchers from SciLifeLab, University of Oslo and MD Anderson Cancer Center have generated a detailed map of protein levels in breast tumors. The proteome complements the previously known DNA and RNA picture of breast cancer and sheds light on how different mutations give rise to changes on the protein level.