Rolf Luft Award 2012

The 2012 Rolf Luft Award was given to Professor David John Mangelsdorf, University of Texas Southwestern Medical Center, Dallas.

Professor David John Mangelsdorf, University of Texas

Mangelsdorf's work on nuclear receptors led to landmark discoveries of how regulatory pathways govern cholesterol, lipid, and bile acid homeostasis. He defined crucial signal-transduction networks in their entirety by identifying the ligands, target genes, physiological functions, and molecular mechanisms for several orphan nuclear receptors. Recently, he has characterized two new signaling pathways mediated by the novel endocrine hormones FGF19 and 21, and established their key roles in regulating metabolism.

Prize Lecture

The Prize Lecture "Nuclear Receptor Regulation of Nutrient Metabolism: From Worms to Humans" was held as Session 1 of the Rolf Luft Symposium on March 16, 2012.

Session 1

Rolf Luft Award and the Rolf Luft Lecture, David John Mangelsdorf, Professor, University of Texas Southwestern Medical Center, Dallas

Session 2

The burden of hypoglycemia, Michael Alvarsson, Associate Professor, MD, PhD, Karolinska University Hospital Solna

Fear of hypoglycemia, Therese Anderbro, psychologist, psychotherapist Karolinska Institutet, Institutionen Danderyds Sjukhus

Evidence linking hypoglycemic events to an increased risk of acute cardiovascular events in patients with type 2 diabetes, Jorge Calles, Professor, Wake Forest University School of medicine, Mexico

Novel Insulins - what to expect from the future, Peter Kurzhalz, Senior Vice President Diabetes Research Unit, Novo Nordisk

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