Research at FyFa

Physiology explores how living organisms, organs, and systems function under normal conditions, focusing on the biological processes that sustain health – such as temperature regulation, circulation, and metabolism. It also investigates how the body responds to stress, extreme environments, and disease, providing insights that contribute to the development of new treatments. At Karolinska Institutet, physiological research forms the foundation of many scientific efforts, including studies on muscle fatigue, exercise physiology, and the mechanisms by which physical activity reduces disease risk.

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Pharmacology is the science of how therapeutic substances interact with living organisms, encompassing their composition, production, toxicity, and medical applications. At Karolinska Institutet, pharmacological research is closely integrated with physiology and clinical practice. Researchers aim to uncover the molecular mechanisms underlying diseases such as cardiovascular conditions, diabetes, cancer, and psychiatric disorders, with the goal of advancing diagnostics, personalized therapies, and the identification of novel therapeutic targets – including but not limited to drug development.

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Anaesthesiology and intensive care covers anaesthesia, anesthetics, and the care of critically ill patients. The research addresses translational questions within physiology, pharmacology, inflammation, neuroscience, and nursing science. The research groups in anaesthesiology and intensive care are part of the clinical operations at the Function for Perioperative Medicine and Intensive Care at Karolinska University Hospital, as well as the Functional Area for Perioperative Medicine and Intensive Care within the Theme Children at Karolinska University Hospital. The research is supported by a broad research platform consisting of the experimental research unit at FyFa and the clinical research and outcomes unit (KFE Solna) at the Function for Perioperative Medicine and Intensive Care, Karolinska University Hospital Solna. Within these translational research environments, interdisciplinary research clusters operate in anaesthesiology, intensive care, and pain management.

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