Publications from FyFa

Publications from researchers at the Department of Physiology and Pharmacology

2024

Decoding the neuroimmune axis in the atopic march: mechanisms and implications.

Brabenec L, Gupta S, Eichwald T, Rafei M, Talbot S.
Curr Opin Immunol. 2024 Nov 22;91:102507. doi: 10.1016/j.coi.2024.102507. Online ahead of print.
PMID: 39579588 Review.

Accuracy of left ventricular mechanical dyssynchrony indices for mechanical characteristics of left bundle branch block using cardiovascular magnetic resonance feature tracking.

Loewenstein DE, Wieslander B, Heiberg E, Axelsson J, Klem I, Nijveldt R, Schelbert EB, Sörensson P, Sigfridsson A, Strauss DG, Kim RJ, Atwater BD, Ugander M.
Eur Heart J Cardiovasc Imaging. 2024 Nov 22:jeae301. doi: 10.1093/ehjci/jeae301. Online ahead of print.
PMID: 39576753

Anabolic Sensitivity in Healthy, Lean, Older Men Is Associated With Higher Expression of Amino Acid Sensors and mTORC1 Activators Compared to Young.

Horwath O, Moberg M, Hodson N, Edman S, Johansson M, Andersson E, van Hall G, Rooyackers O, Philp A, Apró W. J Cachexia Sarcopenia Muscle. 2024 Nov 19. doi: 10.1002/jcsm.13613. Online ahead of print.
PMID: 39558870

Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults.

Badulak J, Abrams D, Luks AM, Zakhary B, Conrad SA, Bartlett R, MacLaren G, Vercaemst L, Lorusso R, Broman LM, Agerstrand C, Price S, Combes A, Peek G, Fan E, Shekar K, Fraser J, Brodie D; Extracorporeal Life Support Organization (ELSO). 
Intensive Care Med. 2024 Nov 18. doi: 10.1007/s00134-024-07645-8. Online ahead of print.
PMID: 39557688 Review.

Morphine treatment restricts response to immunotherapy in oral squamous cell carcinoma.

McIlvried LA, Martel Matos AA, Yuan MM, Atherton MA, Obuekwe F, Nilsen ML, Nikpoor AR, Talbot S, Bruno TC, Taggart DN, Johnson LK, Ferris RL, P Zandberg D, Scheff NN.
J Immunother Cancer. 2024 Nov 17;12(11):e009962. doi: 10.1136/jitc-2024-009962.
PMID: 39551606 Free PMC article.

Is there a rationale for hyperbaric oxygen therapy in the patients with Post COVID syndrome? : A critical review.

Pawlik MT, Rinneberg G, Koch A, Meyringer H, Loew TH, Kjellberg A.
Eur Arch Psychiatry Clin Neurosci. 2024 Dec;274(8):1797-1817. doi: 10.1007/s00406-024-01911-y. Epub 2024 Nov 15.
PMID: 39545965 Free PMC article. Review.

Risk Factors Associated with Weight Gain during Treatment with Dupilumab among Patients with Moderate to Severe Atopic Dermatitis.

Tayefi M, Svedbom A, Ivert L, Lundqvist M, Ruas J, Bradley M, Johansson E.
Acta Derm Venereol. 2024 Nov 15;104:adv40796. doi: 10.2340/actadv.v104.40796.
PMID: 39545373

PharmFreq: a comprehensive atlas of ethnogeographic allelic variation in clinically important pharmacogenes.

Tremmel R, Zhou Y, Camara MD, Laarif S, Eliasson E, Lauschke VM.
Nucleic Acids Res. 2024 Nov 14:gkae1016. doi: 10.1093/nar/gkae1016. Online ahead of print.
PMID: 39540424

The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms.

Pham TCP, Raun SH, Havula E, Henriquez-Olguín C, Rubalcava-Gracia D, Frank E, Fritzen AM, Jannig PR, Andersen NR, Kruse R, Ali MS, Irazoki A, Halling JF, Ringholm S, Needham EJ, Hansen S, Lemminger AK, Schjerling P, Petersen MH, de Almeida ME, Jensen TE, Kiens B, Hostrup M, Larsen S, Ørtenblad N, Højlund K, Kjær M, Ruas JL, Trifunovic A, Wojtaszewski JFP, Nielsen J, Qvortrup K, Pilegaard H, Richter EA, Sylow L.
Nat Commun. 2024 Nov 13;15(1):9826. doi: 10.1038/s41467-024-54183-4.
PMID: 39537626 Free PMC article.

Correction: The impact of preoperative stroke on 1-year mortality and days at home alive after major surgery: an observational cohort study.

Widaeus M, Cedermark A, Bell M.
Perioper Med (Lond). 2024 Nov 12;13(1):109. doi: 10.1186/s13741-024-00467-8.
PMID: 39533339 Free PMC article. No abstract available.

Specialized post-arterial capillaries facilitate adult bone remodelling.

Mohanakrishnan V, Sivaraj KK, Jeong HW, Bovay E, Dharmalingam B, Bixel MG, Dinh VV, Petkova M, Paredes Ugarte I, Kuo YT, Gurusamy M, Raftrey B, Chu NTL, Das S, Rios Coronado PE, Stehling M, Sävendahl L, Chagin AS, Mäkinen T, Red-Horse K, Adams RH.
Nat Cell Biol. 2024 Nov 11. doi: 10.1038/s41556-024-01545-1. Online ahead of print.
PMID: 39528700

Correction to: Modelling to decipher physiological determinants of improved muscle endurance.

Place N, Westerblad H.
Eur J Appl Physiol. 2024 Nov 7. doi: 10.1007/s00421-024-05634-9. Online ahead of print.
PMID: 39505789 No abstract available.

Capnodynamic assessment of mixed venous oxygen saturation in a porcine experimental endotoxemic model.

Svedmyr A, Hedov J, Lipcsey M, Wallin M, Hallbäck M, Lönnqvist PA, Karlsson J.
Sci Rep. 2024 Nov 5;14(1):26807. doi: 10.1038/s41598-024-77483-7.
PMID: 39500994 Free PMC article.

Evaluation of the potential of Ergostatrien-3β-ol for treating Sjögren's syndrome.

Wu PC, Chao YH, Zhang X, Chen TT, Kuo YH, Lin CC, Chang HH.
Int J Rheum Dis. 2024 Nov;27(11):e15341. doi: 10.1111/1756-185X.15341.
PMID: 39498888

The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth.

Edman S, Jones Iii RG, Jannig PR, Fernandez-Gonzalo R, Norrbom J, Thomas NT, Khadgi S, Koopmans PJ, Morena F, Chambers TL, Peterson CS, Scott LN, Greene NP, Figueiredo VC, Fry CS, Zhengye L, Lanner JT, Wen Y, Alkner B, Murach KA, von Walden F.
EMBO Rep. 2024 Oct 31. doi: 10.1038/s44319-024-00299-z. Online ahead of print.
PMID: 39482487

Comprehensive review on leucine-rich pentatricopeptide repeat-containing protein (LRPPRC, PPR protein): A burgeoning target for cancer therapy.

Ge Y, Janson V, Liu H.
Int J Biol Macromol. 2024 Oct 29;282(Pt 3):136820. doi: 10.1016/j.ijbiomac.2024.136820. Online ahead of print.
PMID: 39476900 Review.

Ageing leads to selective type II myofibre deterioration and denervation independent of reinnervative capacity in human skeletal muscle.

Horwath O, Moberg M, Edman S, Philp A, Apró W.
Exp Physiol. 2024 Oct 28. doi: 10.1113/EP092222. Online ahead of print.
PMID: 39466960

A novel model of cardiovascular-kidney-metabolic syndrome combining unilateral nephrectomy and high-salt-sugar-fat diet in mice.

Carvalho LRRA, Shimari M, Boeder AM, Zhuge Z, Cai M, Leijding C, Gastaldello S, Kleschyov AL, Schiffer TA, Guimarães DD, Picozzi G, Lund LH, Fellström B, Weitzberg E, Lundberg JO, Hagberg CE, Pironti G, Andersson DC, Carlström M.
Lab Anim (NY). 2024 Nov;53(11):336-346. doi: 10.1038/s41684-024-01457-5. Epub 2024 Oct 22.
PMID: 39438661 Free PMC article.

A 5-week centrifuge-based G training with feedback on the magnitude of G force does not improve the perception of roll tilt during simulated coordinated turns.

Keramidas ME, Kölegård R, Brink A, Eiken O.
J Neurophysiol. 2024 Nov 1;132(5):1571-1576. doi: 10.1152/jn.00311.2024. Epub 2024 Oct 9.
PMID: 39382978

Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial cochlea.

de Haan S, Corbat AA, Cederroth CR, Autrum LG, Hankeova S, Driver EC, Canlon B, Kelley MW, Andersson ER.
Development. 2024 Nov 1;151(21):dev202949. doi: 10.1242/dev.202949. Epub 2024 Nov 5.
PMID: 39373109 Free PMC article.

Does one biopsy cut it? Revisiting human muscle fiber type composition variability using repeated biopsies in the vastus lateralis and gastrocnemius medialis.

Van de Casteele F, Van Thienen R, Horwath O, Apró W, Van der Stede T, Moberg M, Lievens E, Derave W.
J Appl Physiol (1985). 2024 Nov 1;137(5):1341-1353. doi: 10.1152/japplphysiol.00394.2024. Epub 2024 Oct 3.
PMID: 39359186

Molecular Profiling Defines Three Subtypes of Synovial Sarcoma.

Chen Y, Su Y, Cao X, Siavelis I, Leo IR, Zeng J, Tsagkozis P, Hesla AC, Papakonstantinou A, Liu X, Huang WK, Zhao B, Haglund C, Ehnman M, Johansson H, Lin Y, Lehtiö J, Zhang Y, Larsson O, Li X, de Flon FH.
Adv Sci (Weinh). 2024 Nov;11(41):e2404510. doi: 10.1002/advs.202404510. Epub 2024 Sep 10.
PMID: 39257029

Tocilizumab reduces hypercoagulation in COVID-19 - Perspectives from the coagulation and immunomodulation Covid assessment (Coag-ImmCovA) clinical trial.

Almskog LM, Sjöström A, Sundén-Cullberg J, Taxiarchis A, Ågren A, Freyland S, Börjesson M, Wikman A, Wahlgren CM, Wanecek M, van der Linden J, Antovic J, Lampa J, Magnusson M.
Thromb Res. 2024 Nov;243:109135. doi: 10.1016/j.thromres.2024.109135. Epub 2024 Aug 30.
PMID: 39226747 Clinical Trial.

Senescence detection using reflected light.

Dedic B, Westerberg L, Mosqueda Solís A, Dumont KD, Ruas JL, Thorell A, Näslund E, Spalding KL.
Aging Cell. 2024 Nov;23(11):e14295. doi: 10.1111/acel.14295. Epub 2024 Aug 5.
PMID: 39102872 Free PMC article.

Population-scale variability of the human UDP-glycosyltransferase gene family.

González-Padilla D, Camara MD, Lauschke VM, Zhou Y.
J Genet Genomics. 2024 Nov;51(11):1228-1236. doi: 10.1016/j.jgg.2024.06.018. Epub 2024 Jul 4.
PMID: 38969258

Standardized nomenclature for peripheral percutaneous cannulation of the pulmonary artery in extracorporeal membrane oxygenation: Current uptake and recommendations for improvement.

Brewer JM, Broman LM, Swol J, Lorusso R, Conrad SA, Maybauer MO.
Perfusion. 2024 Nov;39(8):1538-1544. doi: 10.1177/02676591231210457. Epub 2023 Nov 6.
PMID: 37930875 Free PMC article. Review.

Changes in circulating extracellular vesicle cargo are associated with cognitive decline after major surgery: an observational case-control study.

Mkrtchian S, Eldh M, Ebberyd A, Gabrielsson S, Végvári Á, Ricksten SE, Danielson M, Oras J, Wiklund A, Eriksson LI, Gómez-Galán M.

Br J Anaesth. 2024 Oct 18:S0007-0912(24)00553-1. doi: 10.1016/j.bja.2024.07.040. Online ahead of print.

PMID: 39426921

 

Integrating priorities at the intersection of cancer and neuroscience.

Hwang WL, Perrault EN, Birbrair A, Mattson BJ, Gutmann DH, Mabbott DJ, Cukierman E, Repasky EA, Sloan EK, Zong H, Demir IE, Saloman JL, Borniger JC, Hu J, Dietrich J, Breunig JJ, Çifcibaşı K, Ahmad Kasm KA, Valiente M, Wintermark M, Acharya MM, Scheff NN, D'Silva NJ, Vermeer PD, Wong RJ, Talbot S, Hervey-Jumper SL, Wang TC, Ye Y, Pan Y, Bunimovich YL, Amit M.

Cancer Cell. 2024 Oct 15:S1535-6108(24)00362-3. doi: 10.1016/j.ccell.2024.09.014. Online ahead of print.

PMID: 39423816

 

Generation and characterization of a conditional eNOS knock out mouse model for cell-specific reactivation of eNOS in gain-of-function studies.

LoBue A, Li Z, Heuser SK, Li J, Leo F, Vornholz L, Dunaway LS, Suvorava T, Isakson BE, Cortese-Krott MM.

Nitric Oxide. 2024 Oct 15:S1089-8603(24)00136-8. doi: 10.1016/j.niox.2024.10.009. Online ahead of print.

PMID: 39419166

 

The 75-Year Anniversary of the Department of Physiology and Pharmacology at Karolinska Institutet-Examples of Recent Accomplishments and Future Perspectives.

Weitzberg E, Ingelman-Sundberg M, Lundberg JO, Engberg G, Schulte G, Lauschke VM.

Pharmacol Rev. 2024 Oct 16;76(6):1089-1101. doi: 10.1124/pharmrev.124.001433.

PMID: 39414365 Review.

 

TGF-β-mediated crosstalk between TIGIT+ Tregs and CD226+CD8+ T cells in the progression and remission of type 1 diabetes.

Zhong T, Li X, Lei K, Tang R, Deng Q, Love PE, Zhou Z, Zhao B, Li X.

Nat Commun. 2024 Oct 15;15(1):8894. doi: 10.1038/s41467-024-53264-8.

PMID: 39406740 

Free PMC article.
 

Insulin requirement trajectories during COVID-19 versus non-COVID-19 critical illness-A retrospective cohort study.

Soltani N, Häbel H, Balintescu A, Lind M, Grip J, Thobaben R, Nelson D, Mårtensson J.

Acta Anaesthesiol Scand. 2024 Oct 14. doi: 10.1111/aas.14536. Online ahead of print.

PMID: 39402855
 

The effect of eccentric arm cycling on muscle damage and injury-related biomarkers.

Gottschalk F, Gennser M, Eiken O, Elia A.

Clin Physiol Funct Imaging. 2024 Oct 13. doi: 10.1111/cpf.12911. Online ahead of print.

PMID: 39400488
 

Design, synthesis, and biological evaluation of novel 5,7,4'-trimethoxyflavone sulfonamide-based derivatives as highly potent inhibitors of LRPPRC/STAT3/CDK1.

Wu R, Li P, Hao B, Fredimoses M, Ge Y, Zhou Y, Tang L, Li Y, Liu H, Janson V, Hu Y, Liu H.

Bioorg Chem. 2024 Oct 6;153:107878. doi: 10.1016/j.bioorg.2024.107878. Online ahead of print.

PMID: 39395319

 

Neurologic Recovery at Discharge and Long-Term Survival After Cardiac Arrest.

Dillenbeck E, Svensson L, Rawshani A, Hollenberg J, Ringh M, Claesson A, Awad A, Jonsson M, Nordberg P.

JAMA Netw Open. 2024 Oct 1;7(10):e2439196. doi: 10.1001/jamanetworkopen.2024.39196.

PMID: 39392629

 

A 5-week centrifuge-based G training with feedback on the magnitude of G force, does not improve the perception of roll tilt during simulated coordinated turns.

Keramidas ME, Kölegård R, Brink A, Eiken O.

J Neurophysiol. 2024 Oct 9. doi: 10.1152/jn.00311.2024. Online ahead of print.

PMID: 39382978

 

Skeletal stem and progenitor cells in bone physiology, ageing and disease.

Melis S, Trompet D, Chagin AS, Maes C.

Nat Rev Endocrinol. 2024 Oct 8. doi: 10.1038/s41574-024-01039-y. Online ahead of print.

PMID: 39379711 Review.
 

Sudden cardiac death after myocardial infarction: individual participant data from pooled cohorts.

Peek N, Hindricks G, Akbarov A, Tijssen JGP, Jenkins DA, Kapacee Z, Parkes LM, van der Geest RJ, Longato E, Sprague D, Taleb Y, Ong M, Miller CA, Shamloo AS, Albert C, Barthel P, Boveda S, Braunschweig F, Johansen JB, Cook N, de Chillou C, Elders P, Faxén J, Friede T, Fusini L, Gale CP, Jarkovsky J, Jouven X, Junttila J, Kautzner J, Kiviniemi A, Kutyifa V, Leclercq C, Lee DC, Leigh J, Lenarczyk R, Leyva F, Maeng M, Manca A, Marijon E, Marschall U, Merino JL, Mont L, Nielsen JC, Olsen T, Pester J, Pontone G, Roca I, Schmidt G, Schwartz PJ, Sticherling C, Suleiman M, Taborsky M, Tan HL, Tfelt-Hansen J, Thiele H, Tomaselli GF, Verstraelen T, Vinayagamoorthy M, Olesen KKW, Wilde A, Willems R, Wu KC, Zabel M, Martin GP, Dagres N.

Eur Heart J. 2024 Oct 8:ehae326. doi: 10.1093/eurheartj/ehae326. Online ahead of print.

PMID: 39378245

 

Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial cochlea.

de Haan S, Corbat AA, Cederroth CR, Autrum LG, Hankeova S, Driver EC, Canlon B, Kelley MW, Andersson ER.

Development. 2024 Oct 7:dev.202949. doi: 10.1242/dev.202949. Online ahead of print.

PMID: 39373109
 

The phage anti-restriction induced system: new insights into bacterial immunity and bacteriophage escape strategies.

Zhong Y, Lauschke VM.

Signal Transduct Target Ther. 2024 Oct 5;9(1):269. doi: 10.1038/s41392-024-01995-x.

PMID: 39369022 

Free PMC article. Review. No abstract available.
 

Scoping review finds insufficient evidence on potential risks of procedural sedation with dexmedetomidine in children.

Båtelsson A, Lannsjö C, Fläring U, Rooyackers O.

Acta Paediatr. 2024 Oct 4. doi: 10.1111/apa.17435. Online ahead of print.

PMID: 39367630 Review.

 

The impact of preoperative stroke on 1-year mortality and days at home alive after major surgery: an observational cohort study.

Widaeus M, Cederlund A, Bell M.

Perioper Med (Lond). 2024 Oct 4;13(1):97. doi: 10.1186/s13741-024-00453-0.

PMID: 39367494 

Free PMC article.
 

The future is here: an overview of technology in diabetes.

Mallik R, Kar P, Mulder H, Krook A.

Diabetologia. 2024 Oct;67(10):2019-2026. doi: 10.1007/s00125-024-06235-z.

PMID: 39212678 Review. No abstract available.
 

Pharmacological Approaches to Hearing Loss.

Cederroth CR, Dyhrfjeld-Johnsen J, Canlon B.

Pharmacol Rev. 2024 Oct 16;76(6):1063-1088. doi: 10.1124/pharmrev.124.001195.

PMID: 39164117 Review.

 

Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study.

Karamchandani K, Nasa P, Jarzebowski M, Brewster DJ, De Jong A, Bauer PR, Berkow L, Brown CA 3rd, Cabrini L, Casey J, Cook T, Divatia JV, Duggan LV, Ellard L, Ergan B, Jonsson Fagerlund M, Gatward J, Greif R, Higgs A, Jaber S, Janz D, Joffe AM, Jung B, Kovacs G, Kwizera A, Laffey JG, Lascarrou JB, Law JA, Marshall S, McGrath BA, Mosier JM, Perin D, Roca O, Rollé A, Russotto V, Sakles JC, Shrestha GS, Smischney NJ, Sorbello M, Tung A, Jabaley CS, Myatra SN; Society of Critical Care Anesthesiologists (SOCCA) Physiologically Difficult Airway Task Force.

Intensive Care Med. 2024 Oct;50(10):1563-1579. doi: 10.1007/s00134-024-07578-2. Epub 2024 Aug 20.

PMID: 39162823
 

Comparison of drug-induced liver injury risk between propylthiouracil and methimazole: A quantitative systems toxicology approach.

He Q, Li M, Ji P, Zheng A, Yao L, Zhu X, Shin JG, Lauschke VM, Han B, Xiang X.

Toxicol Appl Pharmacol. 2024 Oct;491:117064. doi: 10.1016/j.taap.2024.117064. Epub 2024 Aug 8.

PMID: 39122118
 

New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer.

Espinosa-Bustos C, Bertrand J, Villegas-Menares A, Guerrero S, Di Marcotullio L, Navacci S, Schulte G, Kozielewicz P, Bloch N, Villela V, Paulino M, Kogan MJ, Cantero J, Salas CO.

Bioorg Chem. 2024 Oct;151:107681. doi: 10.1016/j.bioorg.2024.107681. Epub 2024 Jul 28.

PMID: 39106711
 

Validation of a Novel Method for Noninvasive Mixed Venous Oxygen Saturation Monitoring in Anesthetized Children.

Svedmyr A, Steiner K, Andersson A, Sjöberg G, Hallbäck M, Wallin M, Lönnqvist PA, Karlsson J.

Anesth Analg. 2024 Oct 1;139(4):781-788. doi: 10.1213/ANE.0000000000007083. Epub 2024 Aug 2.

PMID: 39093817

 

Quantitative trait locus mapping in placenta: A comparative study of chorionic villus and birth placenta.

Dieckmann L, Lahti-Pulkkinen M, Cruceanu C, Räikkönen K, Binder EB, Czamara D.

HGG Adv. 2024 Oct 10;5(4):100326. doi: 10.1016/j.xhgg.2024.100326. Epub 2024 Jul 10.

PMID: 38993113 

Free PMC article.

 

NanoBiT- and NanoBiT/BRET-based assays allow the analysis of binding kinetics of Wnt-3a to endogenous Frizzled 7 in a colorectal cancer model.

Grätz L, Sajkowska-Kozielewicz JJ, Wesslowski J, Kinsolving J, Bridge LJ, Petzold K, Davidson G, Schulte G, Kozielewicz P.

Br J Pharmacol. 2024 Oct;181(20):3819-3835. doi: 10.1111/bph.16090. Epub 2023 May 6.

PMID: 37055379

Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.

Mantas I, Flais I, Masarapu Y, Ionescu T, Frapard S, Jung F, Le Merre P, Saarinen M, Tiklova K, Salmani BY, Gillberg L, Zhang X, Chergui K, Carlén M, Giacomello S, Hengerer B, Perlmann T, Svenningsson P.

Nat Commun. 2024 Sep 18;15(1):8176. doi: 10.1038/s41467-024-52429-9.

PMID: 39289358

 

Difficulties in running clinical trials on physical activity.

Zavalis EA, Andell P.

Eur Heart J. 2024 Sep 13:ehae582. doi: 10.1093/eurheartj/ehae582. Online ahead of print.

PMID: 39271141 No abstract available.

 

Oncogene-addicted solid tumors and microbiome-lung cancer as a main character: a narrative review.

Guardamagna M, Meyer ML, Berciano-Guerrero MÁ, Mesas-Ruiz A, Cobo-Dols M, Perez-Ruiz E, Cantero Gonzalez A, Lavado-Valenzuela R, Barragán I, Oliver J, Garrido-Aranda A, Alvarez M, Rueda-Dominguez A, Queipo-Ortuño MI, Alba Conejo E, Benitez JC.

Transl Lung Cancer Res. 2024 Aug 31;13(8):2050-2066. doi: 10.21037/tlcr-24-216. Epub 2024 Aug 6.

PMID: 39263011 Free PMC article. Review.

 

Progress on the development of Class A GPCR-biased ligands.

Morales P, Scharf MM, Bermudez M, Egyed A, Franco R, Hansen OK, Jagerovic N, Jakubík J, Keserű GM, Kiss DJ, Kozielewicz P, Larsen O, Majellaro M, Mallo-Abreu A, Navarro G, Prieto-Díaz R, Rosenkilde MM, Sotelo E, Stark H, Werner T, Wingler LM.

Br J Pharmacol. 2024 Sep 11. doi: 10.1111/bph.17301. Online ahead of print.

PMID: 39261899 Review.

 

Molecular Profiling Defines Three Subtypes of Synovial Sarcoma.

Chen Y, Su Y, Cao X, Siavelis I, Leo IR, Zeng J, Tsagkozis P, Hesla AC, Papakonstantinou A, Liu X, Huang WK, Zhao B, Haglund C, Ehnman M, Johansson H, Lin Y, Lehtiö J, Zhang Y, Larsson O, Li X, de Flon FH.

Adv Sci (Weinh). 2024 Sep 10:e2404510. doi: 10.1002/advs.202404510. Online ahead of print.

PMID: 39257029

 

TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION.

Restaino AC, Ahmadi M, Nikpoor AR, Walz A, Balood M, Eichwald T, Talbot S, Vermeer PD.

bioRxiv [Preprint]. 2024 Aug 26:2024.08.23.609450. doi: 10.1101/2024.08.23.609450.

PMID: 39253487 Free PMC article. Preprint.

 

Cerebral microvascular changes in healthy carriers of the APOE-ɛ4 Alzheimer's disease risk gene.

Aamand R, Rasmussen PM, Andersen KS, de Paoli S, Weitzberg E, Christiansen M, Lund TE, Østergaard L.

PNAS Nexus. 2024 Aug 23;3(9):pgae369. doi: 10.1093/pnasnexus/pgae369. eCollection 2024 Sep.

PMID: 39253395 Free PMC article.

 

The duct of von Ebner's glands is a source of Sox10 + taste bud progenitors and susceptible to pathogen infections.

Yu W, Kastriti ME, Ishan M, Choudhary SK, Rashid MM, Kramer N, Do HGT, Wang Z, Xu T, Schwabe RF, Ye K, Adameyko I, Liu HX.

Front Cell Dev Biol. 2024 Aug 23;12:1460669. doi: 10.3389/fcell.2024.1460669. eCollection 2024.

PMID: 39247625 Free PMC article.

 

Targeting the peripheral neural-tumour microenvironment for cancer therapy.

Yaniv D, Mattson B, Talbot S, Gleber-Netto FO, Amit M.

Nat Rev Drug Discov. 2024 Sep 6. doi: 10.1038/s41573-024-01017-z. Online ahead of print.

PMID: 39242781 Review.

 

Unlocking the secrets of exercise: A pathway to enhanced insulin sensitivity and skeletal muscle health in type 2 diabetes.

Zierath JR, Brady AJ, Macgregor KA, de Zevallos JO, Stocks B.

J Sport Health Sci. 2024 Sep 4:100980. doi: 10.1016/j.jshs.2024.100980. Online ahead of print.

PMID: 39241865 No abstract available.

 

Increased risk of cardiac arrhythmia in Hailey-Hailey disease patients.

Jebril W, Curman P, Andersson DC, Larsson H, Bachar-Wikstrom E, Cederlöf M, Wikstrom JD.

PLoS One. 2024 Sep 6;19(9):e0309482. doi: 10.1371/journal.pone.0309482. eCollection 2024.

PMID: 39241028 Free PMC article.

 

Modelling to decipher physiological determinants of improved muscle endurance.

Place N, Westerblad H.

Eur J Appl Physiol. 2024 Sep 6. doi: 10.1007/s00421-024-05590-4. Online ahead of print.

PMID: 39237623 No abstract available.

 

NOCICEPTOR NEURONS CONTROL POLLUTION-MEDIATED NEUTROPHILIC ASTHMA.

Wang JC, Crosson T, Nikpoor AR, Gupta S, Rafei M, Talbot S.

bioRxiv [Preprint]. 2024 Aug 23:2024.08.22.609202. doi: 10.1101/2024.08.22.609202.

PMID: 39229121 Free PMC article. Preprint.

 

Pre-existing maternal cardiovascular disease and the risk of offspring cardiovascular disease from infancy to early adulthood.

Hossin MZ, Kazamia K, Faxén J, Rudolph A, Johansson K, Sandström A, Razaz N.

Eur Heart J. 2024 Sep 4:ehae547. doi: 10.1093/eurheartj/ehae547. Online ahead of print.

PMID: 39228375

 

A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors.

Brands J, Bravo S, Jürgenliemke L, Grätz L, Schihada H, Frechen F, Alenfelder J, Pfeil C, Ohse PG, Hiratsuka S, Kawakami K, Schmacke LC, Heycke N, Inoue A, König G, Pfeifer A, Wachten D, Schulte G, Steinmetzer T, Watts VJ, Gomeza J, Simon K, Kostenis E.

Nat Commun. 2024 Sep 3;15(1):7684. doi: 10.1038/s41467-024-51991-6.

PMID: 39227390 Free PMC article.

 

Tocilizumab reduces hypercoagulation in COVID-19 - Perspectives from the coagulation and immunomodulation Covid assessment (Coag-ImmCovA) clinical trial.

Almskog LM, Sjöström A, Sundén-Cullberg J, Taxiarchis A, Ågren A, Freyland S, Börjesson M, Wikman A, Wahlgren CM, Wanecek M, van der Linden J, Antovic J, Lampa J, Magnusson M.

Thromb Res. 2024 Aug 30;243:109135. doi: 10.1016/j.thromres.2024.109135. Online ahead of print.

PMID: 39226747

 

A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue.

Wadsworth BJ, Leiwe M, Minogue EA, Cunha PP, Engman V, Brombach C, Asvestis C, Sah-Teli SK, Marklund E, Karppinen P, Ruas JL, Rundqvist H, Lanner JT, Johnson RS.

Elife. 2024 Sep 3;12:RP92707. doi: 10.7554/eLife.92707.

PMID: 39226092 Free PMC article.

 

Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastoma.

Olsen TK, Otte J, Mei S, Embaie BT, Kameneva P, Cheng H, Gao T, Zachariadis V, Tsea I, Björklund Å, Kryukov E, Hou Z, Johansson A, Sundström E, Martinsson T, Fransson S, Stenman J, Fard SS, Johnsen JI, Kogner P, Adameyko I, Enge M, Kharchenko PV, Baryawno N.

Mol Cancer. 2024 Aug 31;23(1):180. doi: 10.1186/s12943-024-02091-y.

PMID: 39217332 Free PMC article.

 

Organoids and chimeras: the hopeful fusion transforming traumatic brain injury research.

Bellotti C, Samudyata S, Thams S, Sellgren CM, Rostami E.

Acta Neuropathol Commun. 2024 Aug 30;12(1):141. doi: 10.1186/s40478-024-01845-5.

PMID: 39215375 Free PMC article. Review.

 

Nitrate: "the source makes the poison".

Bowles EF, Burleigh M, Mira A, Van Breda SGJ, Weitzberg E, Rosier BT.

Crit Rev Food Sci Nutr. 2024 Aug 30:1-27. doi: 10.1080/10408398.2024.2395488. Online ahead of print.

PMID: 39213282 Review.

 

The future is here: an overview of technology in diabetes.

Mallik R, Kar P, Mulder H, Krook A.

Diabetologia. 2024 Aug 30. doi: 10.1007/s00125-024-06235-z. Online ahead of print.

PMID: 39212678 No abstract available.

 

Serum from patients with idiopathic inflammatory myopathy induces skeletal muscle weakness.

Leijding C, Kaewin S, Andreasson KM, Horuluoglu B, Galindo-Feria AS, Van Gompel E, Dastmalchi M, Gastaldello S, Alexanderson H, Lundberg IE, Andersson DC.

Ann Rheum Dis. 2024 Aug 28:ard-2024-225912. doi: 10.1136/ard-2024-225912. Online ahead of print.

PMID: 39197873 No abstract available.

 

Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody.

Jungholm O, Trkulja C, Moche M, Srinivasa SP, Christakopoulou MN, Davidson M, Reymer A, Jardemark K, Fogaça RL, Ashok A, Jeffries G, Ampah-Korsah H, Strandback E, Andréll J, Nyman T, Nouairia G, Orwar O.

Sci Rep. 2024 Aug 23;14(1):19656. doi: 10.1038/s41598-024-70217-9.

PMID: 39179604 Free PMC article.

 

Comparison of lactate measurements from earlobe and fingertip capillary blood using Biosen S-Line and lactate scout analyzers.

Zhong F, Chen Z, Gu Z, Wang X, Holmberg HC, Li Y.

Eur J Appl Physiol. 2024 Aug 20. doi: 10.1007/s00421-024-05585-1. Online ahead of print.

PMID: 39164441

 

Pharmacological Approaches to Hearing Loss.

Cederroth CR, Dyhrfjeld-Johnsen J, Canlon B.

Pharmacol Rev. 2024 Aug 20:PHARMREV-AR-2024-001195. doi: 10.1124/pharmrev.124.001195. Online ahead of print.

PMID: 39164117

 

Arrhythmia in patients with systemic sclerosis: incidence, risk factors and impact on mortality in a Swedish register-based study.

Bairkdar M, Dong Z, Andell P, Hesselstrand R, Holmqvist M.

RMD Open. 2024 Aug 20;10(3):e004532. doi: 10.1136/rmdopen-2024-004532.

PMID: 39164050 Free PMC article.

 

Volumetric Assessment of Traumatic Intracranial Hematomas: Is ABC/2 Reliable?

Fletcher-Sandersjöö A, Lewén A, Hånell A, Nelson DW, Maegele M, Svensson M, Bellander BM, Enblad P, Thelin EP, Svedung Wettervik T.

J Neurotrauma. 2024 Sep 4. doi: 10.1089/neu.2024.0248. Online ahead of print.

PMID: 39162998

 

Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study.

Karamchandani K, Nasa P, Jarzebowski M, Brewster DJ, De Jong A, Bauer PR, Berkow L, Brown CA 3rd, Cabrini L, Casey J, Cook T, Divatia JV, Duggan LV, Ellard L, Ergan B, Jonsson Fagerlund M, Gatward J, Greif R, Higgs A, Jaber S, Janz D, Joffe AM, Jung B, Kovacs G, Kwizera A, Laffey JG, Lascarrou JB, Law JA, Marshall S, McGrath BA, Mosier JM, Perin D, Roca O, Rollé A, Russotto V, Sakles JC, Shrestha GS, Smischney NJ, Sorbello M, Tung A, Jabaley CS, Myatra SN; Society of Critical Care Anesthesiologists (SOCCA) Physiologically Difficult Airway Task Force.

Intensive Care Med. 2024 Aug 20. doi: 10.1007/s00134-024-07578-2. Online ahead of print.

PMID: 39162823

 

Muscle memory in humans: evidence for myonuclear permanence and long-term transcriptional regulation after strength training.

Cumming KT, Reitzner SM, Hanslien M, Skilnand K, Seynnes OR, Horwath O, Psilander N, Sundberg CJ, Raastad T.

J Physiol. 2024 Sep;602(17):4171-4193. doi: 10.1113/JP285675. Epub 2024 Aug 19.

PMID: 39159314

 

Intracranial pressure monitoring in adult patients with traumatic brain injury: challenges and innovations.

Zoerle T, Beqiri E, Åkerlund CAI, Gao G, Heldt T, Hawryluk GWJ, Stocchetti N.

Lancet Neurol. 2024 Sep;23(9):938-950. doi: 10.1016/S1474-4422(24)00235-7.

PMID: 39152029 Review.

 

Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodeling.

Correia JC, Jannig PR, Gosztyla ML, Cervenka I, Ducommun S, Præstholm SM, Dias JM, Dumont KD, Liu Z, Liang Q, Edsgärd D, Emanuelsson O, Gregorevic P, Westerblad H, Venckunas T, Brazaitis M, Kamandulis S, Lanner JT, Teixeira AI, Yeo GW, Ruas JL.

Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e2319724121. doi: 10.1073/pnas.2319724121. Epub 2024 Aug 14.

PMID: 39141348

 

Using the GAP score as a complement to the NISS score in identifying severely injured patients- A registry-based cohort study of adult trauma patients in Sweden.

Granström A, Schandl A, Mårtensson J, Strömmer L.

Injury. 2024 Sep;55(9):111709. doi: 10.1016/j.injury.2024.111709. Epub 2024 Jun 28.

PMID: 38969590

 

Discovery of a novel inhibitor of macropinocytosis with antiviral activity.

Porebski B, Christ W, Corman A, Haraldsson M, Barz M, Lidemalm L, Häggblad M, Ilmain J, Wright SC, Murga M, Schlegel J, Jarvius M, Lapins M, Sezgin E, Bhabha G, Lauschke VM, Carreras-Puigvert J, Lafarga M, Klingström J, Hühn D, Fernandez-Capetillo O.

Mol Ther. 2024 Sep 4;32(9):3012-3024. doi: 10.1016/j.ymthe.2024.06.038. Epub 2024 Jul 2.

PMID: 38956870

 

The role of zinc and matrix metalloproteinases in myofibrillar protein degradation in critical illness myopathy.

Ribeiro F, Zhang X, Wen Y, Cacciani N, Hedström Y, Xia Z, Schulz R, Larsson L.

Free Radic Biol Med. 2024 Sep;222:493-504. doi: 10.1016/j.freeradbiomed.2024.06.022. Epub 2024 Jun 27.

PMID: 38944212

 

Eccentric exercise before a 90 min exposure at 24,000 ft increases decompression strain depending on body region but not total muscle mass recruited.

Gottschalk F, Gennser M, Günther M, Eiken O, Elia A.

Exp Physiol. 2024 Sep;109(9):1517-1528. doi: 10.1113/EP091853. Epub 2024 Jun 26.

PMID: 38923893 Free PMC article.

 

The rRNA epitranscriptome and myonuclear SNORD landscape in skeletal muscle fibers contributes to ribosome heterogeneity and is altered by a hypertrophic stimulus.

Cui M, Jannig P, Halladjian M, Figueiredo VC, Wen Y, Vechetti IJ, Krogh N, Jude B, Edman S, Lanner J, McCarthy J, Murach KA, Sejersen T, Nielsen H, von Walden F.

Am J Physiol Cell Physiol. 2024 Sep 1;327(3):C516-C524. doi: 10.1152/ajpcell.00301.2024. Epub 2024 Jun 24.

PMID: 38912733

 

Diacylglycerol kinase delta overexpression improves glucose clearance and protects against the development of obesity.

Jollet M, Tramontana F, Jiang LQ, Borg ML, Savikj M, Kuefner MS, Massart J, de Castro Barbosa T, Mannerås-Holm L, Checa A, Pillon NJ, Chibalin AV, Björnholm M, Zierath JR.

Metabolism. 2024 Sep;158:155939. doi: 10.1016/j.metabol.2024.155939. Epub 2024 Jun 4.

PMID: 38843995

 

Central Venopulmonary Extracorporeal Membrane Oxygenation: Background and Standardized Nomenclature.

Brewer JM, Lorusso R, Broman LM, Conrad SA, Swol J, Maybauer MO.

ASAIO J. 2024 Sep 1;70(9):e123-e128. doi: 10.1097/MAT.0000000000002239. Epub 2024 May 20.

PMID: 38768563 Free PMC article. Review.

 

Long-term neurological and neurocognitive impairments after tick-borne encephalitis in Lithuania - a prospective study.

Griška V, Pranckevičienė A, Pakalnienė J, Gabrijolavičiūtė D, Veje M, Studahl M, Ahlberg J, Schwieler L, Lindquist L, Mickienė A.

Infect Dis (Lond). 2024 Sep;56(9):732-742. doi: 10.1080/23744235.2024.2346793. Epub 2024 May 6.

PMID: 38709658

 

Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction.

Suda M, Paul KH, Tripathi U, Minamino T, Tchkonia T, Kirkland JL.

Endocr Rev. 2024 Sep 12;45(5):655-675. doi: 10.1210/endrev/bnae010.

PMID: 38500373 Free PMC article. Review.

 

A Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 Levels in Chondrocytes of Different Morphology within Nondegenerate and Early Osteoarthritic Human Femoral Head Cartilage.

Herren AOF, Amin AK, Hall AC.

Cartilage. 2024 Sep;15(3):278-282. doi: 10.1177/19476035231176532. Epub 2023 Jun 5.

PMID: 37272453 No abstract available.

Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism.

Nomura K, Kinoshita S, Mizusaki N, Senga Y, Sasaki T, Kitamura T, Sakaue H, Emi A, Hosooka T, Matsuo M, Okamura H, Amo T, Wolf AM, Kamimura N, Ohta S, Itoh T, Hayashi Y, Kiyonari H, Krook A, Zierath JR, Kasuga M, Ogawa W.

Mol Metab. 2024 Jun 15:101968. doi: 10.1016/j.molmet.2024.101968. Online ahead of print.

PMID: 38885788
 

3D atlas of the human fetal chondrocranium in the middle trimester.

Kaiser M, Zikmund T, Vora S, Metscher B, Adameyko I, Richman JM, Kaiser J.

Sci Data. 2024 Jun 13;11(1):626. doi: 10.1038/s41597-024-03455-1.

PMID: 38871782 Free PMC article.
 

Remedy hope for polycystic ovary syndrome.

Stener-Victorin E.

Science. 2024 Jun 14;384(6701):1174-1175. doi: 10.1126/science.adq0328. Epub 2024 Jun 13.

PMID: 38870311
 

Effects of weight loss intervention on anxiety, depression and quality of life in women with severe obesity and polycystic ovary syndrome.

Kataoka J, Olsson M, Lindgren E, Larsson I, Schmidt J, Benrick A, Stener-Victorin E.

Sci Rep. 2024 Jun 12;14(1):13495. doi: 10.1038/s41598-024-63166-w.

PMID: 38866860 Free PMC article.
 

Nitric Oxide Signaling and Regulation in the Cardiovascular System: Recent Advances.

Carlstrom M, Weitzberg E, Lundberg JO.

Pharmacol Rev. 2024 Jun 12:PHARMREV-AR-2023-001060. doi: 10.1124/pharmrev.124.001060. Online ahead of print.

PMID: 38866562
 

Basing intubation of acutely hypoxemic patients on physiologic principles.

Laghi F, Shaikh H, Caccani N.

Ann Intensive Care. 2024 Jun 12;14(1):86. doi: 10.1186/s13613-024-01327-w.

PMID: 38864960 Free PMC article. Review.
 

Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach.

Beausoleil C, Thébault A, Andersson P, Cabaton NJ, Ermler S, Fromenty B, Garoche C, Griffin JL, Hoffmann S, Kamstra JH, Kubickova B, Lenters V, Kos VM, Poupin N, Remy S, Sapounidou M, Zalko D, Legler J, Jacobs MN, Rousselle C.

Toxicol Appl Pharmacol. 2024 Jun 9:116995. doi: 10.1016/j.taap.2024.116995. Online ahead of print.

PMID: 38862081
 

Mood, Cognitive Function, and Plasma Kynurenine Metabolites Responses Following Severe Changes in Physical Activity.

Sigitas K, Inga L, Audrius S, Marius B, Mantas M, Margarita C, Jorge R, Lilly S, Varvara L, Sophie E, Hakan W, Tomas V.

Med Sci Sports Exerc. 2024 Jun 6. doi: 10.1249/MSS.0000000000003488. Online ahead of print.

PMID: 38857520
 

Diacylglycerol kinase delta overexpression improves glucose clearance and protects against the development of obesity.

Jollet M, Tramontana F, Jiang LQ, Borg ML, Savikj M, Kuefner MS, Massart J, de Castro Barbosa T, Mannerås-Holm L, Checa A, Pillon NJ, Chibalin AV, Björnholm M, Zierath JR.

Metabolism. 2024 Jun 4:155939. doi: 10.1016/j.metabol.2024.155939. Online ahead of print.

PMID: 38843995
 

Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue.

Jevans B, Cooper F, Fatieieva Y, Gogolou A, Kang YN, Restuadi R, Moulding D, Vanden Berghe P, Adameyko I, Thapar N, Andrews PW, De Coppi P, Tsakiridis A, McCann CJ.

Gut. 2024 May 30:gutjnl-2023-331532. doi: 10.1136/gutjnl-2023-331532. Online ahead of print.

PMID: 38816188
 

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y, Pirmann S, Lauschke VM.

Pharmacogenomics J. 2024 May 27;24(3):17. doi: 10.1038/s41397-024-00338-x.

PMID: 38802404 Free PMC article.

 

The out-of-pocket expenses of people with tinnitus in Europe.

Jarach CM, Karydou K, Trochidis I, Bernal-Robledano A, van den Brandt PA, Cima R, Cederroth CR, Lopez-Escamez JA, Ghislandi S, Hall DA, Kikidis D, Langguth B, Lugo A, Mazurek B, Odone A, Schecklmann M, Schoisswohl S, Simoes J, Schlee W, Gallus S.

J Epidemiol. 2024 May 25. doi: 10.2188/jea.JE20230358. Online ahead of print.

PMID: 38797674
 

Exploring the effect of prolonged fasting on kynurenine pathway metabolites and stress markers in healthy male individuals.

Louvrou V, Solianik R, Brazaitis M, Erhardt S.

Eur J Clin Nutr. 2024 May 24. doi: 10.1038/s41430-024-01451-7. Online ahead of print.

PMID: 38789718
 

Central Venopulmonary Extracorporeal Membrane Oxygenation: Background and Standardized Nomenclature.

Brewer JM, Lorusso R, Broman LM, Conrad SA, Swol J, Maybauer MO.

ASAIO J. 2024 May 20. doi: 10.1097/MAT.0000000000002239. Online ahead of print.

PMID: 38768563
 

Androgens Modulate the Immune Profile in a Mouse Model of Polycystic Ovary Syndrome.

Torstensson S, Ascani A, Risal S, Lu H, Zhao A, Espinosa A, Lindgren E, Johansson MH, Eriksson G, Barakat M, Karlsson MCI, Svensson C, Benrick A, Stener-Victorin E.

Adv Sci (Weinh). 2024 May 20:e2401772. doi: 10.1002/advs.202401772. Online ahead of print.

PMID: 38767114
 

Performance of Subcutaneous Continuous Glucose Monitoring in Adult Critically Ill Patients Receiving Vasopressor Therapy.

Friman O, Soltani N, Lind M, Zetterqvist P, Balintescu A, Perner A, Oldner A, Rooyackers O, Mårtensson J.

Diabetes Technol Ther. 2024 May 31. doi: 10.1089/dia.2024.0035. Online ahead of print.

PMID: 38758211
 

Sex matters: Is it time for a SOFA makeover?

Larsson E.

Crit Care. 2024 Aug 8;28(1):268. doi: 10.1186/s13054-024-05030-x.

PMID: 39118159 Free PMC article. No abstract available.
 

Pharmacogenetic Variants and Plasma Concentrations of Antiseizure Drugs: A Systematic Review and Meta-Analysis.

Milosavljevic F, Manojlovic M, Matkovic L, Molden E, Ingelman-Sundberg M, Leucht S, Jukic MM.

JAMA Netw Open. 2024 Aug 1;7(8):e2425593. doi: 10.1001/jamanetworkopen.2024.25593.

PMID: 39115847 Free PMC article.
 

New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer.

Espinosa-Bustos C, Bertrand J, Villegas-Menares A, Guerrero S, Di Marcotullio L, Navacci S, Schulte G, Kozielewicz P, Bloch N, Villela V, Paulino M, Kogan MJ, Cantero J, Salas CO.

Bioorg Chem. 2024 Jul 28;151:107681. doi: 10.1016/j.bioorg.2024.107681. Online ahead of print.

PMID: 39106711
 

Integrating gender analysis into research: reflections from the Gender-Net Plus workshop.

Cederroth CR, Earp BD, Gómez Prada HC, Jarach CM, Lir SA, Norris CM, Pilote L, Raparelli V, Rochon P, Sahraoui N, Simmon C, Vissandjee B, Mour C, Arbogast M, Armengol JM, Mason R.

EClinicalMedicine. 2024 Jul 13;74:102728. doi: 10.1016/j.eclinm.2024.102728. eCollection 2024 Aug.

PMID: 39105192 Free PMC article. Review.
 

Senescence detection using reflected light.

Dedic B, Westerberg L, Mosqueda Solís A, Dumont KD, Ruas JL, Thorell A, Näslund E, Spalding KL.

Aging Cell. 2024 Aug 5:e14295. doi: 10.1111/acel.14295. Online ahead of print.

PMID: 39102872
 

Validation of a Novel Method for Noninvasive Mixed Venous Oxygen Saturation Monitoring in Anesthetized Children.

Svedmyr A, Steiner K, Andersson A, Sjöberg G, Hallbäck M, Wallin M, Lönnqvist PA, Karlsson J.

Anesth Analg. 2024 Aug 2. doi: 10.1213/ANE.0000000000007083. Online ahead of print.

PMID: 39093817
 

Application of FRET- and BRET-based live-cell biosensors in deorphanization and ligand discovery studies on orphan G protein-coupled receptors.

Sajkowska JJ, Tsang CH, Kozielewicz P.

SLAS Discov. 2024 Jul 29;29(6):100174. doi: 10.1016/j.slasd.2024.100174. Online ahead of print.

PMID: 39084335 Review.
 

A genetic-epigenetic interplay at 1q21.1 locus underlies CHD1L-mediated vulnerability to primary progressive multiple sclerosis.

Pahlevan Kakhki M, Giordano A, Starvaggi Cucuzza C, Venkata S Badam T, Samudyata S, Lemée MV, Stridh P, Gkogka A, Shchetynsky K, Harroud A, Gyllenberg A, Liu Y, Boddul S, James T, Sorosina M, Filippi M, Esposito F, Wermeling F, Gustafsson M, Casaccia P, Hillert J, Olsson T, Kockum I, Sellgren CM, Golzio C, Kular L, Jagodic M.

Nat Commun. 2024 Jul 30;15(1):6419. doi: 10.1038/s41467-024-50794-z.

PMID: 39079955 Free PMC article.
 

Time to Throw Out the Elephant in the Room: Proper Use of SvO2 in Extracorporeal Life Support.

Broman LM, Brewer JM, Lorusso R, Belliato M, Maybauer MO, Broomé M.

ASAIO J. 2024 Jul 31. doi: 10.1097/MAT.0000000000002290. Online ahead of print.

PMID: 39079089 No abstract available.
 

Dissecting the Impact of Maternal Androgen Exposure on Developmental Programming through Targeting the Androgen Receptor.

Lu H, Jiang H, Li C, Derisoud E, Zhao A, Eriksson G, Lindgren E, Pui HP, Risal S, Pei Y, Maxian T, Ohlsson C, Benrick A, Haider S, Stener-Victorin E, Deng Q.

Adv Sci (Weinh). 2024 Jul 29:e2309429. doi: 10.1002/advs.202309429. Online ahead of print.

PMID: 39075722
 

OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.

Mickols E, Meyer A, Handin N, Stüwe M, Eriksson J, Rudfeldt J, Blom K, Fryknäs M, Sellin ME, Lauschke VM, Karlgren M, Artursson P.

Sci Rep. 2024 Jul 27;14(1):17334. doi: 10.1038/s41598-024-67192-6.

PMID: 39068198 Free PMC article.
 

Which compartments of the optic nerve and its sheath are associated with intracranial pressure? An exploratory study.

Pansell J, Bottai M, Bell M, Rudberg PC, Friman O, Cooray C.

J Neuroimaging. 2024 Jul 21. doi: 10.1111/jon.13224. Online ahead of print.

PMID: 39034603
 

A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade.

Li W, Pan L, Hong W, Ginhoux F, Zhang X, Xiao C, Li X.

Nat Commun. 2024 Jul 21;15(1):6142. doi: 10.1038/s41467-024-50478-8.

PMID: 39034339 Free PMC article.
 

The Effect of Dietary Nitrate on the Oral Microbiome and Salivary Biomarkers in Individuals with High Blood Pressure.

du Toit L, Sundqvist ML, Redondo-Rio A, Brookes Z, Casas-Agustench P, Hickson M, Benavente A, Montagut G, Weitzberg E, Gabaldón T, Lundberg JO, Bescos R.

J Nutr. 2024 Jul 16:S0022-3166(24)00382-1. doi: 10.1016/j.tjnut.2024.07.002. Online ahead of print.

PMID: 39019159
 

Influence of spatial orientation training in a centrifuge on the ability of fighter pilots to assess the bank angle during flight without visual references.

Brink A, Keramidas ME, Bergsten E, Eiken O.

J Neurophysiol. 2024 Jul 17. doi: 10.1152/jn.00129.2024. Online ahead of print.

PMID: 39015074
 

Dynamic immunoediting by macrophages in homologous recombination deficiency-stratified pancreatic ductal adenocarcinoma.

Hong WF, Zhang F, Wang N, Bi JM, Zhang DW, Wei LS, Song ZT, Mills GB, Chen MM, Li XX, Du SS, Yu M.

Drug Resist Updat. 2024 Jul 6;76:101115. doi: 10.1016/j.drup.2024.101115. Online ahead of print.

PMID: 39002266
 

Quantitative trait locus mapping in placenta: A comparative study of chorionic villus and birth placenta.

Dieckmann L, Lahti-Pulkkinen M, Cruceanu C, Räikkönen K, Binder EB, Czamara D.

HGG Adv. 2024 Jul 10;5(4):100326. doi: 10.1016/j.xhgg.2024.100326. Online ahead of print.

PMID: 38993113
 

Factors affecting adherence to recommendations on pre-operative cardiac testing: A cohort study.

Stroda A, Sulot T, Roth S, M'Pembele R, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck Schimmer B, Spadaro S, Matute P, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Larmann J, Corneci D, Howell SJ, Lurati Buse G; and the MET-REPAIR investigators.

Eur J Anaesthesiol. 2024 Sep 1;41(9):695-704. doi: 10.1097/EJA.0000000000002039. Epub 2024 Jul 10.

PMID: 38988248
 

Onset of Prolonged High-Potency Benzodiazepine Use Among ICU Survivors: A Nationwide Cohort Study.

Lindström AC, von Oelreich E, Eriksson J, Eriksson M, Mårtensson J, Larsson E, Oldner A.

Crit Care Explor. 2024 Jul 8;6(7):e1124. doi: 10.1097/CCE.0000000000001124. eCollection 2024 Jul.

PMID: 38984149 Free PMC article.
 

Early Creatinine Changes After Aortic Valve Replacement and Late Survival, Heart Failure, and Chronic Kidney Disease in a National Registry.

Lu R, Dismorr M, Hertzberg D, Glaser N, Sartipy U.

Ann Thorac Surg. 2024 Jul 4:S0003-4975(24)00541-1. doi: 10.1016/j.athoracsur.2024.06.021. Online ahead of print.

PMID: 38971227q
 

Population-scale variability of the human UDP-glycosyltransferase gene family.

González-Padilla D, Camara MD, Lauschke VM, Zhou Y.

J Genet Genomics. 2024 Jul 3:S1673-8527(24)00161-9. doi: 10.1016/j.jgg.2024.06.018. Online ahead of print.

PMID: 38969258
 

Discovery of a novel inhibitor of macropinocytosis with antiviral activity.

Porebski B, Christ W, Corman A, Haraldsson M, Barz M, Lidemalm L, Häggblad M, Ilmain J, Wright SC, Murga M, Schlegel J, Jarvius M, Lapins M, Sezgin E, Bhabha G, Lauschke VM, Carreras-Puigvert J, Lafarga M, Klingström J, Hühn D, Fernandez-Capetillo O.

Mol Ther. 2024 Jul 2:S1525-0016(24)00455-6. doi: 10.1016/j.ymthe.2024.06.038. Online ahead of print.

PMID: 38956870
 

Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge.

Gasbjerg LS, Rasmussen RS, Dragan A, Lindquist P, Melchiorsen JU, Stepniewski TM, Schiellerup S, Tordrup EK, Gadgaard S, Kizilkaya HS, Willems S, Zhong Y, Wang Y, Wright SC, Lauschke VM, Hartmann B, Holst JJ, Selent J, Rosenkilde MM.

Br J Pharmacol. 2024 Jul 1. doi: 10.1111/bph.16478. Online ahead of print.

PMID: 38952084
 

The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.

Kibalnyk Y, Afanasiev E, Noble RMN, Watson AES, Poverennaya I, Dittmann NL, Alexiou M, Goodkey K, Greenwell AA, Ussher JR, Adameyko I, Massey J, Graf D, Bourque SL, Stratton JA, Voronova A.

Nat Commun. 2024 Jul 1;15(1):4632. doi: 10.1038/s41467-024-48955-1.

PMID: 38951500 Free PMC article.
 

CAS3D: 3D quantitative morphometry on Second Harmonic Generation image volumes from single skeletal muscle fibers.

Schneidereit D, Bauer J, Mnuskina S, Nübler S, Cacciani N, Mühlberg A, Kreiss L, Ritter P, Schürmann S, Larsson L, Friedrich O.

Comput Biol Med. 2024 Aug;178:108618. doi: 10.1016/j.compbiomed.2024.108618. Epub 2024 Jun 25.

PMID: 38925088
 

Unraveling the neuroimmune interface in chronic pain-the association between cytokines in the cerebrospinal fluid and pain in patients with lumbar disk herniation or degenerative disk disease.

Rosenström AHC, Ahmed AS, Kultima K, Freyhult E, Berg S, Bersellini Farinotti A, Palada V, Svensson CI, Kosek E.

Pain. 2024 Jul 1;165(7):e65-e79. doi: 10.1097/j.pain.0000000000003175. Epub 2024 Feb 5.

PMID: 38900144 Free PMC article.
 

Antibody-mediated autoimmunity in symptom-based disorders: position statement and proceedings from an international workshop.

Mountford R, Adler BL, Andersson D, Bashford-Rogers R, Berwick R, Bevan S, Caro X, Chung TH, Clark JD, Dawes JM, Dong X, Helyes Z, Kingery W, van Middendorp JJ, Neiland H, Maurer M, Scheibenbogen C, Schmack K, Schreiner T, Svensson CI, Tékus V, Goebel A.

Pain Rep. 2024 Jun 12;9(4):e1167. doi: 10.1097/PR9.0000000000001167. eCollection 2024 Aug.

PMID: 38873615 Free PMC article.
 

Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes.

Kizilkaya HS, Sørensen KV, Madsen JS, Lindquist P, Douros JD, Bork-Jensen J, Berghella A, Gerlach PA, Gasbjerg LS, Mokrosiński J, Mowery SA, Knerr PJ, Finan B, Campbell JE, D'Alessio DA, Perez-Tilve D, Faas F, Mathiasen S, Rungby J, Sørensen HT, Vaag A, Nielsen JS, Holm JC, Lauenborg J, Damm P, Pedersen O, Linneberg A, Hartmann B, Holst JJ, Hansen T, Wright SC, Lauschke VM, Grarup N, Hauser AS, Rosenkilde MM.

Nat Metab. 2024 Jul;6(7):1268-1281. doi: 10.1038/s42255-024-01061-4. Epub 2024 Jun 13.

PMID: 38871982 Free PMC article.
 

Airway pressure release ventilation (APRV) versus pressure support ventilation (PSV)-A prospective intervention trial comparing haemodynamic parameters in intensive care patients.

Ille A, Nilsson C, Sjödin C, Daham S, Persson P, Svensson CJ.

Acta Anaesthesiol Scand. 2024 Aug;68(7):932-939. doi: 10.1111/aas.14434. Epub 2024 May 19.

PMID: 38764089
 

A prospective 12-month structured weight loss intervention in women with severe obesity and polycystic ovary syndrome: Impact of weight loss on eating behaviors.

Kataoka J, Stener-Victorin E, Schmidt J, Larsson I.

Acta Obstet Gynecol Scand. 2024 Aug;103(8):1615-1624. doi: 10.1111/aogs.14867. Epub 2024 May 8.

PMID: 38717931 Free PMC article. Clinical Trial.
 

Skeletal stem and progenitor cells in bone development and repair.

Trompet D, Melis S, Chagin AS, Maes C.

J Bone Miner Res. 2024 Jul 23;39(6):633-654. doi: 10.1093/jbmr/zjae069.

PMID: 38696703 Review.
 

Audio podcast and procedural video use in anaesthesiology and intensive care: A nationwide survey of Swedish anaesthetists.

Bjurström MF, Borgquist O, Kander T, Lundén R, Fagerlund MJ, Lipcsey M, Sturesson LW.

Acta Anaesthesiol Scand. 2024 Aug;68(7):923-931. doi: 10.1111/aas.14433. Epub 2024 Apr 30.

PMID: 38686931
 

Rare variants and clozapine: Reply.

van Westrhenen R, Ingelman-Sundberg M.

Eur Neuropsychopharmacol. 2024 Jul;84:16-17. doi: 10.1016/j.euroneuro.2024.03.004. Epub 2024 Apr 20.

PMID: 38643694 No abstract available.
 

Acute experimental inflammation in healthy women attenuates empathy for psychological pain.

Flasbeck V, Dersch N, Engler H, Schedlowski M, Brüne M.

Brain Behav Immun. 2024 Jul;119:1-5. doi: 10.1016/j.bbi.2024.03.032. Epub 2024 Mar 27.

PMID: 38548183 Clinical Trial.
 

Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies.

Derisoud E, Jiang H, Zhao A, Chavatte-Palmer P, Deng Q.

Hum Reprod Update. 2024 Jul 1;30(4):410-441. doi: 10.1093/humupd/dmae006.

PMID: 38478759 Free PMC article.

Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism.

Nomura K, Kinoshita S, Mizusaki N, Senga Y, Sasaki T, Kitamura T, Sakaue H, Emi A, Hosooka T, Matsuo M, Okamura H, Amo T, Wolf AM, Kamimura N, Ohta S, Itoh T, Hayashi Y, Kiyonari H, Krook A, Zierath JR, Kasuga M, Ogawa W.

Mol Metab. 2024 Jun 15:101968. doi: 10.1016/j.molmet.2024.101968. Online ahead of print.

PMID: 38885788

 

3D atlas of the human fetal chondrocranium in the middle trimester.

Kaiser M, Zikmund T, Vora S, Metscher B, Adameyko I, Richman JM, Kaiser J.

Sci Data. 2024 Jun 13;11(1):626. doi: 10.1038/s41597-024-03455-1.

PMID: 38871782 Free PMC article.

 

Remedy hope for polycystic ovary syndrome.

Stener-Victorin E.

Science. 2024 Jun 14;384(6701):1174-1175. doi: 10.1126/science.adq0328. Epub 2024 Jun 13.

PMID: 38870311

 

Effects of weight loss intervention on anxiety, depression and quality of life in women with severe obesity and polycystic ovary syndrome.

Kataoka J, Olsson M, Lindgren E, Larsson I, Schmidt J, Benrick A, Stener-Victorin E.

Sci Rep. 2024 Jun 12;14(1):13495. doi: 10.1038/s41598-024-63166-w.

PMID: 38866860 Free PMC article.

 

Nitric Oxide Signaling and Regulation in the Cardiovascular System: Recent Advances.

Carlstrom M, Weitzberg E, Lundberg JO.

Pharmacol Rev. 2024 Jun 12:PHARMREV-AR-2023-001060. doi: 10.1124/pharmrev.124.001060. Online ahead of print.

PMID: 38866562

 

Basing intubation of acutely hypoxemic patients on physiologic principles.

Laghi F, Shaikh H, Caccani N.

Ann Intensive Care. 2024 Jun 12;14(1):86. doi: 10.1186/s13613-024-01327-w.

PMID: 38864960 Free PMC article. Review.

 

Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach.

Beausoleil C, Thébault A, Andersson P, Cabaton NJ, Ermler S, Fromenty B, Garoche C, Griffin JL, Hoffmann S, Kamstra JH, Kubickova B, Lenters V, Kos VM, Poupin N, Remy S, Sapounidou M, Zalko D, Legler J, Jacobs MN, Rousselle C.

Toxicol Appl Pharmacol. 2024 Jun 9:116995. doi: 10.1016/j.taap.2024.116995. Online ahead of print.

PMID: 38862081

 

Mood, Cognitive Function, and Plasma Kynurenine Metabolites Responses Following Severe Changes in Physical Activity.

Sigitas K, Inga L, Audrius S, Marius B, Mantas M, Margarita C, Jorge R, Lilly S, Varvara L, Sophie E, Hakan W, Tomas V.

Med Sci Sports Exerc. 2024 Jun 6. doi: 10.1249/MSS.0000000000003488. Online ahead of print.

PMID: 38857520

 

Diacylglycerol kinase delta overexpression improves glucose clearance and protects against the development of obesity.

Jollet M, Tramontana F, Jiang LQ, Borg ML, Savikj M, Kuefner MS, Massart J, de Castro Barbosa T, Mannerås-Holm L, Checa A, Pillon NJ, Chibalin AV, Björnholm M, Zierath JR.

Metabolism. 2024 Jun 4:155939. doi: 10.1016/j.metabol.2024.155939. Online ahead of print.

PMID: 38843995

 

Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue.

Jevans B, Cooper F, Fatieieva Y, Gogolou A, Kang YN, Restuadi R, Moulding D, Vanden Berghe P, Adameyko I, Thapar N, Andrews PW, De Coppi P, Tsakiridis A, McCann CJ.

Gut. 2024 May 30:gutjnl-2023-331532. doi: 10.1136/gutjnl-2023-331532. Online ahead of print.

PMID: 38816188

 

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y, Pirmann S, Lauschke VM.

Pharmacogenomics J. 2024 May 27;24(3):17. doi: 10.1038/s41397-024-00338-x.

PMID: 38802404 Free PMC article.

 

The out-of-pocket expenses of people with tinnitus in Europe.

Jarach CM, Karydou K, Trochidis I, Bernal-Robledano A, van den Brandt PA, Cima R, Cederroth CR, Lopez-Escamez JA, Ghislandi S, Hall DA, Kikidis D, Langguth B, Lugo A, Mazurek B, Odone A, Schecklmann M, Schoisswohl S, Simoes J, Schlee W, Gallus S.

J Epidemiol. 2024 May 25. doi: 10.2188/jea.JE20230358. Online ahead of print.

PMID: 38797674

 

Exploring the effect of prolonged fasting on kynurenine pathway metabolites and stress markers in healthy male individuals.

Louvrou V, Solianik R, Brazaitis M, Erhardt S.

Eur J Clin Nutr. 2024 May 24. doi: 10.1038/s41430-024-01451-7. Online ahead of print.

PMID: 38789718

 

Central Venopulmonary Extracorporeal Membrane Oxygenation: Background and Standardized Nomenclature.

Brewer JM, Lorusso R, Broman LM, Conrad SA, Swol J, Maybauer MO.

ASAIO J. 2024 May 20. doi: 10.1097/MAT.0000000000002239. Online ahead of print.

PMID: 38768563

 

Androgens Modulate the Immune Profile in a Mouse Model of Polycystic Ovary Syndrome.

Torstensson S, Ascani A, Risal S, Lu H, Zhao A, Espinosa A, Lindgren E, Johansson MH, Eriksson G, Barakat M, Karlsson MCI, Svensson C, Benrick A, Stener-Victorin E.

Adv Sci (Weinh). 2024 May 20:e2401772. doi: 10.1002/advs.202401772. Online ahead of print.

PMID: 38767114

 

Performance of Subcutaneous Continuous Glucose Monitoring in Adult Critically Ill Patients Receiving Vasopressor Therapy.

Friman O, Soltani N, Lind M, Zetterqvist P, Balintescu A, Perner A, Oldner A, Rooyackers O, Mårtensson J.

Diabetes Technol Ther. 2024 May 31. doi: 10.1089/dia.2024.0035. Online ahead of print.

PMID: 38758211

Airway pressure release ventilation (APRV) versus pressure support ventilation (PSV)-A prospective intervention trial comparing haemodynamic parameters in intensive care patients.

Ille A, Nilsson C, Sjödin C, Daham S, Persson P, Svensson CJ.

Acta Anaesthesiol Scand. 2024 May 19. doi: 10.1111/aas.14434. Online ahead of print. PMID: 38764089

 

Performance of subcutaneous continuous glucose monitoring in adult critically ill patients receiving vasopressor therapy.

Friman O, Soltani N, Lind M, Zetterqvist P, Balintescu A, Perner A, Oldner A, Rooyackers O, Mårtensson J.

Diabetes Technol Ther. 2024 May 17. doi: 10.1089/dia.2024.0035. Online ahead of print. PMID: 38758211

 

A prospective 12-month structured weight loss intervention in women with severe obesity and polycystic ovary syndrome: Impact of weight loss on eating behaviors.

Kataoka J, Stener-Victorin E, Schmidt J, Larsson I.

Acta Obstet Gynecol Scand. 2024 May 8. doi: 10.1111/aogs.14867. Online ahead of print. PMID: 38717931 Review.

 

Long-term neurological and neurocognitive impairments after tick-borne encephalitis in Lithuania - a prospective study.

Griška V, Pranckevičienė A, Pakalnienė J, Gabrijolavičiūtė D, Veje M, Studahl M, Ahlberg J, Schwieler L, Lindquist L, Mickienė A.

Infect Dis (Lond). 2024 May 6:1-11. doi: 10.1080/23744235.2024.2346793. Online ahead of print. PMID: 38709658

 

Hospitalized patients' attitudes towards participating in a randomized control trial in case of a cardiac arrest.

Albert M, Thonander M, Forsberg S, Lindgren F, Thuccani M, Odell A, Skoglund K, Bergh N, Hollenberg J, Ringh M, Jonsson M, Nordberg P, Lundgren P.

Resusc Plus. 2024 Apr 26;18:100645. doi: 10.1016/j.resplu.2024.100645. eCollection 2024 Jun. PMID: 38708065 Free PMC article.

 

Intensive care in children with non-Hodgkin lymphoma in Sweden.

Ranta S, Broman LM, Mellgren K, Norén-Nyström U, Svahn JE, Törnudd L, Heyman M, Harila A.

Acta Paediatr. 2024 May 4. doi: 10.1111/apa.17258. Online ahead of print.

PMID: 38703016 No abstract available.

 

Correction: Introducing Braining-physical exercise as adjunctive therapy in psychiatric care: a retrospective cohort study of a new method.

Anger Å, Wallerblad A, Kaaman L, Broman R, Holmberg J, Lundgren T, Salomonsson S, Sundberg CJ, Martinsson L.

BMC Psychiatry. 2024 May 3;24(1):337. doi: 10.1186/s12888-024-05775-3.

PMID: 38702666 Free PMC article. No abstract available.

 

Enterococcus faecalis: implications for host health.

Boeder AM, Spiller F, Carlstrom M, Izídio GS.

World J Microbiol Biotechnol. 2024 May 4;40(6):190. doi: 10.1007/s11274-024-04007-w. PMID: 38702495 Review.

 

Kidney Doppler Ultrasonography in Critical Care Nephrology.

Corradi F, Bell M, De Rosa S.

Nephrol Dial Transplant. 2024 May 2:gfae103. doi: 10.1093/ndt/gfae103. Online ahead of print. PMID: 38697934

 

Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity.

Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG.

Nat Metab. 2024 Apr 30. doi: 10.1038/s42255-024-01038-3. Online ahead of print. PMID: 38689023

 

Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6.

Guimarães DSPSF, Barrios NMF, de Oliveira AG, Rizo-Roca D, Jollet M, Smith JAB, Araujo TR, da Cruz MV, Marconato E Jr, Hirabara SM, Vieira AS, Krook A, Zierath JR, Silveira LR.

J Cachexia Sarcopenia Muscle. 2024 Apr 29. doi: 10.1002/jcsm.13480. Online ahead of print. PMID: 38682559

 

Novel Blood Biomarkers for Response Prediction and Monitoring of Stereotactic Ablative Radiotherapy and Immunotherapy in Metastatic Oligoprogressive Lung Cancer.

Zafra J, Onieva JL, Oliver J, Garrido-Barros M, González-Hernández A, Martínez-Gálvez B, Román A, Ordóñez-Marmolejo R, Pérez-Ruiz E, Benítez JC, Mesas A, Vera A, Chicas-Sett R, Rueda-Domínguez A, Barragán I.

Int J Mol Sci. 2024 Apr 20;25(8):4533. doi: 10.3390/ijms25084533.

PMID: 38674117 Free PMC article.

 

MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study.

Ye S, Agalave NM, Ma F, Mahmood DFD, Al-Grety A, Khoonsari PE, Leng L, Svensson CI, Bucala R, Kultima K, Vera PL.

Int J Mol Sci. 2024 Apr 19;25(8):4484. doi: 10.3390/ijms25084484.

PMID: 38674069 Free PMC article.

 

Specific NOX4 Inhibition Preserves Mitochondrial Function and Dampens Kidney Dysfunction Following Ischemia-Reperfusion-Induced Kidney Injury.

Schiffer TA, Carvalho LRRA, Guimaraes D, Boeder A, Wikström P, Carlström M.

Antioxidants (Basel). 2024 Apr 19;13(4):489. doi: 10.3390/antiox13040489.

PMID: 38671936 Free PMC article.

 

Exploring dietary changes and supplement use among cancer patients in Norway: prevalence, motivations, disclosure, information, and perceived risks and benefits: a cross sectional study.

Kristoffersen AE, Stub T, Nilsen JV, Nordberg JH, Broderstad AR, Wider B, Bjelland M.

BMC Nutr. 2024 Apr 26;10(1):65. doi: 10.1186/s40795-024-00872-8.

PMID: 38671478 Free PMC article.

 

Kynurenine Metabolites in CSF and Plasma in Healthy Males.

Orhan F, Schwieler L, Engberg G, Samuelsson M.

Int J Tryptophan Res. 2024 Apr 24;17:11786469241245323. doi: 10.1177/11786469241245323. eCollection 2024.

PMID: 38665132 Free PMC article.

 

Sex differences in the diagnostic value of optic nerve sheath diameter for assessing intracranial pressure.

Pansell J, Rudberg PC, Friman O, Bell M, Cooray C.

Sci Rep. 2024 Apr 25;14(1):9553. doi: 10.1038/s41598-024-60489-6.

PMID: 38664502 Free PMC article.

 

Single Cell Atlas: a single-cell multi-omics human cell encyclopedia.

Pan L, Parini P, Tremmel R, Loscalzo J, Lauschke VM, Maron BA, Paci P, Ernberg I, Tan NS, Liao Z, Yin W, Rengarajan S, Li X; SCA Consortium.

Genome Biol. 2024 Apr 19;25(1):104. doi: 10.1186/s13059-024-03246-2.

PMID: 38641842 Free PMC article.

 

Comparison of Human Long-Term Liver Models for Clearance Prediction of Slowly Metabolized Compounds.

Preiss LC, Georgi K, Lauschke VM, Petersson C.

Drug Metab Dispos. 2024 May 16;52(6):539-547. doi: 10.1124/dmd.123.001638. PMID: 38604730

 

Frizzleds act as dynamic pharmacological entities.

Schulte G, Scharf MM, Bous J, Voss JH, Grätz L, Kozielewicz P.

Trends Pharmacol Sci. 2024 May;45(5):419-429. doi: 10.1016/j.tips.2024.03.003. Epub 2024 Apr 8. PMID: 38594145 Review.

 

Consistent and effective method to define the mouse estrous cycle stage by a deep learning-based model.

Strauss L, Junnila A, Wärri A, Manti M, Jiang Y, Löyttyniemi E, Stener-Victorin E, Lagerquist MK, Kukoricza K, Heinosalo T, Blom S, Poutanen M.

J Endocrinol. 2024 May 6;261(3):e230204. doi: 10.1530/JOE-23-0204. Print 2024 Jun 1. PMID: 38593833

 

Individualized Pharmacotherapy Utilizing Genetic Biomarkers and Novel In Vitro Systems As Predictive Tools for Optimal Drug Development and Treatment.

Ingelman-Sundberg M, Lauschke VM.

Drug Metab Dispos. 2024 May 16;52(6):467-475. doi: 10.1124/dmd.123.001302. PMID: 38575185 Review.

 

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy.

Camara MD, Zhou Y, Dara A, Tékété MM, Nóbrega de Sousa T, Sissoko S, Dembélé L, Ouologuem N, Hamidou Togo A, Alhousseini ML, Fofana B, Sagara I, Djimde AA, Gil PJ, Lauschke VM.

Antimicrob Agents Chemother. 2024 May 2;68(5):e0139023. doi: 10.1128/aac.01390-23. Epub 2024 Mar 28. PMID: 38546223 Free PMC article.

 

Inflammatory, metabolic, and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia.

Di Martino E, Ambikan A, Ramsköld D, Umekawa T, Giatrellis S, Vacondio D, Romero AL, Galán MG, Sandberg R, Ådén U, Lauschke VM, Neogi U, Blomgren K, Kele J.

iScience. 2024 Feb 28;27(4):109346. doi: 10.1016/j.isci.2024.109346. eCollection 2024 Apr 19. PMID: 38500830 Free PMC article.

 

Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression.

Krontira AC, Cruceanu C, Dony L, Kyrousi C, Link MH, Rek N, Pöhlchen D, Raimundo C, Penner-Goeke S, Schowe A, Czamara D, Lahti-Pulkkinen M, Sammallahti S, Wolford E, Heinonen K, Roeh S, Sportelli V, Wölfel B, Ködel M, Sauer S, Rex-Haffner M, Räikkönen K, Labeur M, Cappello S, Binder EB.

Neuron. 2024 May 1;112(9):1426-1443.e11. doi: 10.1016/j.neuron.2024.02.005. Epub 2024 Mar 4. PMID: 38442714

 

The design of the PRINCESS 2 trial: A randomized trial to study the impact of ultrafast hypothermia on complete neurologic recovery after out-of-hospital cardiac arrest with initial shockable rhythm.

Dillenbeck E, Hollenberg J, Holzer M, Busch HJ, Nichol G, Radsel P, Belohlavec J, Torres EC, López-de-Sa E, Rosell F, Ristagno G, Forsberg S, Annoni F, Svensson L, Jonsson M, Bäckström D, Gellerfors M, Awad A, Taccone FS, Nordberg P.

Am Heart J. 2024 May;271:97-108. doi: 10.1016/j.ahj.2024.02.020. Epub 2024 Feb 28. PMID: 38417773 Clinical Trial.

 

Cognitive Function and Variability in Antipsychotic Drug-Naive Patients With First-Episode Psychosis: A Systematic Review and Meta-Analysis.

Lee M, Cernvall M, Borg J, Plavén-Sigray P, Larsson C, Erhardt S, Sellgren CM, Fatouros-Bergman H, Cervenka S.

JAMA Psychiatry. 2024 May 1;81(5):468-476. doi: 10.1001/jamapsychiatry.2024.0016. PMID: 38416480 Free PMC article.

 

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment.

Ingelman-Sundberg M, Pirmohamed M.

J Intern Med. 2024 May;295(5):583-598. doi: 10.1111/joim.13772. Epub 2024 Feb 11. PMID: 38343077 Review.

 

Outcomes of SARS-CoV-2 infection in early pregnancy-A systematic review and meta-analysis.

Rodriguez-Wallberg KA, Nilsson HP, Røthe EB, Zhao A, Shah PS, Acharya G.

Acta Obstet Gynecol Scand. 2024 May;103(5):786-798. doi: 10.1111/aogs.14764. Epub 2024 Jan 10. PMID: 38200686 Free PMC article. Review.

 

Unraveling the role of Slc10a4 in auditory processing and sensory motor gating: Implications for neuropsychiatric disorders?

Ciralli B, Malfatti T, Hilscher MM, Leao RN, Cederroth CR, Leao KE, Kullander K.

Prog Neuropsychopharmacol Biol Psychiatry. 2024 Apr 20;131:110930. doi: 10.1016/j.pnpbp.2023.110930. Epub 2023 Dec 30. PMID: 38160852

The gonadal niche safeguards human fetal germline cell development following maternal SARS-CoV-2 infection.

Shen S, Wang M, Li X, Wang B, Hong W, Li W, Xu B, Guo Z, Han R, Yi S, Wu Z, He X, Wang L, Zhu Q, Yang G, Wang H, Deng Q, Chen J, Gao S, Jiang C, Gao R.

Cell Rep Med. 2024 Apr 9:101515. doi: 10.1016/j.xcrm.2024.101515. Online ahead of print.

PMID: 38631348

 

Comparison of preoxygenation using a tight facemask, humidified high-flow nasal oxygen and a standard nasal cannula - a volunteer, randomised, crossover study.

Sjöblom A, Hedberg M, Forsberg IM, Hoffman F, Jonsson Fagerlund M.

Eur J Anaesthesiol. 2024 Apr 16. doi: 10.1097/EJA.0000000000001989. Online ahead of print.

PMID: 38630525

 

Comparison of Human Long-Term Liver Models for Clearance Prediction of Slowly Metabolized Compounds.

Preiss LC, Georgi K, Lauschke VM, Petersson C.

Drug Metab Dispos. 2024 Apr 11:DMD-AR-2023-001638. doi: 10.1124/dmd.123.001638. Online ahead of print.

PMID: 38604730

 

Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis.

Czamara D, Dieckmann L, Lahti-Pulkkinen M, Cruceanu C, Henrich W, Plagemann A, Räikkönen K, Braun T, Binder EB, Lahti J, Entringer S.

Cell Mol Life Sci. 2024 Apr 10;81(1):177. doi: 10.1007/s00018-024-05208-0.

PMID: 38600394 

Free PMC article.

 

Frizzleds act as dynamic pharmacological entities.

Schulte G, Scharf MM, Bous J, Voss JH, Grätz L, Kozielewicz P.

Trends Pharmacol Sci. 2024 Apr 8:S0165-6147(24)00051-8. doi: 10.1016/j.tips.2024.03.003. Online ahead of print.

PMID: 38594145 Review.

 

Consistent and effective method to define the mouse estrous cycle stage by deep learning based model.

Strauss L, Junnila A, Wärri A, Manti M, Jiang Y, Löyttyniemi E, Stener-Victorin E, Lagerquist MK, Kukoricza K, Heinosalo T, Blom S, Poutanen M.

J Endocrinol. 2024 Apr 1:JOE-23-0204. doi: 10.1530/JOE-23-0204. Online ahead of print.

PMID: 38593833

 

3D printed orthopedic prostheses for domestic and wild birds-case reports.

Carvalho LRRA.

Sci Rep. 2024 Apr 5;14(1):7989. doi: 10.1038/s41598-024-58762-9.

PMID: 38580783 

Free PMC article.

 

Individualized pharmacotherapy utilizing genetic biomarkers and novel in vitro systems as predictive tools for optimal drug development and treatment.

Ingelman-Sundberg M, Lauschke VM.

Drug Metab Dispos. 2024 Apr 4:DMD-MR-2023-001302. doi: 10.1124/dmd.123.001302. Online ahead of print.

PMID: 38575185

 

Young adults' perception of transition from paediatric to adult care.

Forsberg J, Lööf G, Burström Å.

Acta Paediatr. 2024 Apr 3. doi: 10.1111/apa.17231. Online ahead of print.

PMID: 38568009

 

Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium.

Grommisch D, Wang M, Eenjes E, Svetličič M, Deng Q, Giselsson P, Genander M.

Dev Cell. 2024 Mar 28:S1534-5807(24)00179-5. doi: 10.1016/j.devcel.2024.03.011. Online ahead of print.

PMID: 38565145

 

Building resilience: analysis of health care leaders' perspectives on the Covid-19 response in Region Stockholm.

Savage C, Tragl L, Castillo MM, Azizi L, Hasson H, Sundberg CJ, Mazzocato P.

BMC Health Serv Res. 2024 Apr 2;24(1):408. doi: 10.1186/s12913-024-10886-4.

PMID: 38561762 

Free PMC article.

 

Advanced chronic kidney disease after surgery and the contribution of acute kidney disease: a national observational cohort study.

Renberg M, Hertzberg D, Rimes-Stigare C, Hallqvist L, Bell M.

Br J Anaesth. 2024 Mar 28:S0007-0912(24)00106-5. doi: 10.1016/j.bja.2024.02.024. Online ahead of print.

PMID: 38553313

 

Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells.

Monteil VM, Wright SC, Dyczynski M, Kellner MJ, Appelberg S, Platzer SW, Ibrahim A, Kwon H, Pittarokoilis I, Mirandola M, Michlits G, Devignot S, Elder E, Abdurahman S, Bereczky S, Bagci B, Youhanna S, Aastrup T, Lauschke VM, Salata C, Elaldi N, Weber F, Monserrat N, Hawman DW, Feldmann H, Horn M, Penninger JM, Mirazimi A.

Nat Microbiol. 2024 Mar 28. doi: 10.1038/s41564-024-01672-3. Online ahead of print.

PMID: 38548922

 

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy.

Camara MD, Zhou Y, Dara A, Tékété MM, Nóbrega de Sousa T, Sissoko S, Dembélé L, Ouologuem N, Hamidou Togo A, Alhousseini ML, Fofana B, Sagara I, Djimde AA, Gil PJ, Lauschke VM.

Antimicrob Agents Chemother. 2024 Mar 28:e0139023. doi: 10.1128/aac.01390-23. Online ahead of print.

PMID: 38546223

 

The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling.

Xie M, Kaiser M, Gershtein Y, Schnyder D, Deviatiiarov R, Gazizova G, Shagimardanova E, Zikmund T, Kerckhofs G, Ivashkin E, Batkovskyte D, Newton PT, Andersson O, Fried K, Gusev O, Zeberg H, Kaiser J, Adameyko I, Chagin AS.

Nat Commun. 2024 Mar 26;15(1):2367. doi: 10.1038/s41467-024-46030-3.

PMID: 38531868 

Free PMC article.

 

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response.

Ingelman-Sundberg M, Molden E.

Br J Clin Pharmacol. 2024 Mar 24. doi: 10.1111/bcp.16048. Online ahead of print.

PMID: 38523083 Review.

 

Erratum to 'Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study' (Br J Anaesth 2024; 132: 811-4).

Roth S, M'Pembele R, Nienhaus J, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck-Schimmer B, Spadaro S, Matute P, Bolliger D, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Wulf H, Larmann J, Corneci D, Chammartin F, Howell SJ, Buse GL; MET: Reevaluation for Perioperative Cardiac Risk Investigators.

Br J Anaesth. 2024 Mar 23:S0007-0912(24)00124-7. doi: 10.1016/j.bja.2024.03.002. Online ahead of print.

PMID: 38521659 No abstract available.

 

Genetic contribution to microglial activation in schizophrenia.

Koskuvi M, Pörsti E, Hewitt T, Räsänen N, Wu YC, Trontti K, McQuade A, Kalyanaraman S, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Blurton-Jones M, Hovatta I, Lähteenvuo M, Rolova T, Lehtonen Š, Tiihonen J, Koistinaho J.

Mol Psychiatry. 2024 Mar 22. doi: 10.1038/s41380-024-02529-1. Online ahead of print.

PMID: 38519640

 

Painful differences between different pain scale assessments: The outcome of assessed pain is a matter of the choices of scale and statistics.

Svensson E, Lund I.

Scand J Pain. 2024 Mar 19;24(1). doi: 10.1515/sjpain-2023-0113. eCollection 2024 Jan 1.

PMID: 38502712

 

Appropriate glycemic management protects the germline but not the uterine environment in hyperglycemia.

Zhao A, Jiang H, Palomares AR, Larsson A, He W, Grünler J, Zheng X, Rodriguez Wallberg KA, Catrina SB, Deng Q.

EMBO Rep. 2024 Apr;25(4):1752-1772. doi: 10.1038/s44319-024-00097-7. Epub 2024 Mar 15.

PMID: 38491313 

Free PMC article.

 

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C, Gallardo-Dodd CJ, Savva C, Hases L, Birgersson M, Indukuri R, Shen JX, Carravilla P, Geng K, Nørskov Søndergaard J, Ferrer-Aumatell C, Mercier G, Sezgin E, Korach-André M, Petersson C, Hagström H, Lauschke VM, Archer A, Williams C, Kutter C.

Mol Syst Biol. 2024 Apr;20(4):374-402. doi: 10.1038/s44320-024-00024-x. Epub 2024 Mar 8.

PMID: 38459198 

Free PMC article.

 

Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition.

Ducommun S, Jannig PR, Cervenka I, Murgia M, Mittenbühler MJ, Chernogubova E, Dias JM, Jude B, Correia JC, Van Vranken JG, Ocana-Santero G, Porsmyr-Palmertz M, McCann Haworth S, Martínez-Redondo V, Liu Z, Carlström M, Mann M, Lanner JT, Teixeira AI, Maegdefessel L, Spiegelman BM, Ruas JL.

Mol Metab. 2024 Apr;82:101912. doi: 10.1016/j.molmet.2024.101912. Epub 2024 Mar 6.

PMID: 38458566 

Free PMC article.

 

Navigating the blurred path of mixed neuroimmune signaling.

Gupta S, Viotti A, Eichwald T, Roger A, Kaufmann E, Othman R, Ghasemlou N, Rafei M, Foster SL, Talbot S.

J Allergy Clin Immunol. 2024 Apr;153(4):924-938. doi: 10.1016/j.jaci.2024.02.006. Epub 2024 Feb 17.

PMID: 38373475 Review.

 

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials.

Milosavljević F, Molden PE, Ingelman-Sundberg PM, Jukić APMM.

Eur Neuropsychopharmacol. 2024 Apr;81:43-52. doi: 10.1016/j.euroneuro.2024.01.005. Epub 2024 Feb 9.

PMID: 38340605

 

Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study.

Stroda A, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck Schimmer B, Spadaro S, Matute P, Ganter MT, Ovezov A, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Larmann J, Corneci D, Buggy DJ, Howell SJ, Lurati Buse G; MET-REPAIR investigators.

Br J Anaesth. 2024 Apr;132(4):675-684. doi: 10.1016/j.bja.2023.12.036. Epub 2024 Feb 9.

PMID: 38336516

 

Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study.

Roth S, M'Pembele R, Nienhaus J, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck-Schimmer B, Spadaro S, Matute P, Bolliger D, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Wulf H, Larmann J, Corneci D, Chammartin F, Howell SJ, Lurati Buse G; MET: Reevaluation for Perioperative Cardiac Risk Investigators.

Br J Anaesth. 2024 Apr;132(4):811-814. doi: 10.1016/j.bja.2024.01.003. Epub 2024 Feb 6.

PMID: 38326210 No abstract available.

 

The success rate and complications of midline catheters in pediatric outpatient parenteral antibiotic therapy (OPAT).

Fläring U, Lundevall H, Norberg Å, Andersson A.

Eur J Pediatr. 2024 Apr;183(4):1703-1709. doi: 10.1007/s00431-024-05432-7. Epub 2024 Jan 16.

PMID: 38227054 

Free PMC article.

 

Pre-oxygenation using high-flow nasal oxygen versus tight facemask in trauma patients undergoing emergency anaesthesia.

Sjöblom A, Hedberg M, Gille A, Guerra A, Aanesen V, Forsberg IM, Fagerlund MJ.

Acta Anaesthesiol Scand. 2024 Apr;68(4):447-456. doi: 10.1111/aas.14368. Epub 2023 Dec 21.

PMID: 38129931

 

Incidence and risk factors of peri-operative stroke in major non-cardiovascular, non-neurologic surgery-A retrospective register-based cohort study.

Falck-Jones R, Bell M, Hallqvist L.

Acta Anaesthesiol Scand. 2024 Apr;68(4):485-492. doi: 10.1111/aas.14373. Epub 2024 Jan 11.

PMID: 38212290

 

Correction to: Role of Toll-like receptor 2 and 4 signaling pathways on the inflammatory response to resistance training in elderly subjects.

Rodriguez-Miguelez P, Fernandez-Gonzalo R, Almar M, Mejías Y, Rivas A, de Paz JA, Cuevas MJ, González-Gallego J.

Geroscience. 2024 Apr;46(2):2799. doi: 10.1007/s11357-023-01027-6.

PMID: 38064045 

Free PMC article. No abstract available.

 

Therapy Intensity Level Scale for Traumatic Brain Injury: Clinimetric Assessment on Neuro-Monitored Patients Across 52 European Intensive Care Units.

Bhattacharyay S, Beqiri E, Zuercher P, Wilson L, Steyerberg EW, Nelson DW, Maas AIR, Menon DK, Ercole A.

J Neurotrauma. 2024 Apr;41(7-8):887-909. doi: 10.1089/neu.2023.0377. Epub 2023 Nov 2.

PMID: 37795563 

Free PMC article.

 

A Solution to the Cerebral Perfusion Pressure Transducer Placement Conundrum in Neurointensive Care? The Dual Transducer.

Mikkonen E, Blixt J, Ercole A, Alpkvist P, Sköldbring R, Bellander BM, Weitzberg E, Nelson DW.

Neurocrit Care. 2024 Apr;40(2):391-394. doi: 10.1007/s12028-023-01829-8. Epub 2023 Sep 11.

PMID: 37697130 Free PMC article.

Appropriate glycemic management protects the germline but not the uterine environment in hyperglycemia.

Zhao A, Jiang H, Palomares AR, Larsson A, He W, Grünler J, Zheng X, Rodriguez Wallberg KA, Catrina SB, Deng Q.

EMBO Rep. 2024 Mar 15. doi: 10.1038/s44319-024-00097-7. Online ahead of print.

PMID: 38491313

 

Implementation of an extracorporeal resuscitation (ECPR) program for out-of-hospital cardiac arrest in Stockholm, Sweden: Feasibility, safety, and outcome.

Frykler Abazi L, Liliequist A, Böhm F, Hedberg M, Simonsson M, Bäckman A, Ax M, Braunschweig F, Mellbin L, Linder R, Svensson L, Jurga J, Nordberg P, Ringh M, Forsberg S, Hollenberg J.

Resusc Plus. 2024 Mar 7;18:100596. doi: 10.1016/j.resplu.2024.100596. eCollection 2024 Jun.

PMID: 38486930 

Free PMC article.

 

Detection of acute pulmonary embolism using native repeated magnetic resonance imaging acquisitions under free-breathing and without respiratory or cardiac gating. A diagnostic accuracy study.

Medson K, Vargas Paris R, Fyrdahl A, Wiklund P, Nyren S, Westerlund E, Lindholm P.

Eur J Radiol Open. 2024 Mar 5;12:100558. doi: 10.1016/j.ejro.2024.100558. eCollection 2024 Jun.

PMID: 38482518 

Free PMC article.

 

Multimodality imaging of acute and chronic pulmonary thromboembolic disease.

Muscogiuri E, De Wever W, Gopalan D.

Breathe (Sheff). 2024 Mar;20(1):230130. doi: 10.1183/20734735.0130-2023. Epub 2024 Mar 12.

PMID: 38482190 

Free PMC article. Review.

 

Wrestling with a ghost: facing an opponent I can neither see nor clinch - the experience of professional wrestlers who have suffered an ACL injury.

Piussi R, Nilsson E, Karlsson H, Hägglund M, Ivarsson A, Samuelsson K, Holmberg HC, Hamrin Senorski E.

BMJ Open Sport Exerc Med. 2024 Mar 12;10(1):e001782. doi: 10.1136/bmjsem-2023-001782. eCollection 2024.

PMID: 38481557 

Free PMC article.

 

Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice.

Pendergrast LA, Ashcroft SP, Ehrlich AM, Treebak JT, Krook A, Dollet L, Zierath JR.

Metabolism. 2024 Mar 11:155834. doi: 10.1016/j.metabol.2024.155834. Online ahead of print.

PMID: 38479569

 

Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies.

Derisoud E, Jiang H, Zhao A, Chavatte-Palmer P, Deng Q.

Hum Reprod Update. 2024 Mar 13:dmae006. doi: 10.1093/humupd/dmae006. Online ahead of print.

PMID: 38478759

 

Statin-Sensitive Akt1/Src/Caveolin-1 Signaling Enhances Oxidative Stress Resistance in Rhabdomyosarcoma.

Codenotti S, Sandrini L, Mandracchia D, Lorenzi L, Corsetti G, Poli M, Asperti M, Salvi V, Bosisio D, Monti E, Mitola S, Triggiani L, Guescini M, Pozzo E, Sampaolesi M, Gastaldello S, Cassandri M, Marampon F, Fanzani A.

Cancers (Basel). 2024 Feb 20;16(5):853. doi: 10.3390/cancers16050853.

PMID: 38473215

 

The effect of neuromuscular electrical stimulation on the human skeletal muscle transcriptome.

Flodin J, Reitzner SM, Emanuelsson EB, Sundberg CJ, Ackermann P.

Acta Physiol (Oxf). 2024 Mar 8:e14129. doi: 10.1111/apha.14129. Online ahead of print.

PMID: 38459757

 

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C, Gallardo-Dodd CJ, Savva C, Hases L, Birgersson M, Indukuri R, Shen JX, Carravilla P, Geng K, Nørskov Søndergaard J, Ferrer-Aumatell C, Mercier G, Sezgin E, Korach-André M, Petersson C, Hagström H, Lauschke VM, Archer A, Williams C, Kutter C.

Mol Syst Biol. 2024 Mar 8. doi: 10.1038/s44320-024-00024-x. Online ahead of print.

PMID: 38459198

 

Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition.

Ducommun S, Jannig PR, Cervenka I, Murgia M, Mittenbühler MJ, Chernogubova E, Dias JM, Jude B, Correia JC, Van Vranken JG, Ocana-Santero G, Porsmyr-Palmertz M, McCann Haworth S, Martínez-Redondo V, Liu Z, Carlström M, Mann M, Lanner JT, Teixeira AI, Maegdefessel L, Spiegelman BM, Ruas JL.

Mol Metab. 2024 Mar 6;82:101912. doi: 10.1016/j.molmet.2024.101912. Online ahead of print.

PMID: 38458566

 

Cancer-associated muscle weakness - From triggers to molecular mechanisms.

Shorter E, Engman V, Lanner JT.

Mol Aspects Med. 2024 Mar 7;97:101260. doi: 10.1016/j.mam.2024.101260. Online ahead of print.

PMID: 38457901 Review.

 

Hepatic Inhibition of ANGPTL3 Mimics the Molecular Hallmarks of Hypothyroidism.

Taebnia N, Lauschke VM.

Arterioscler Thromb Vasc Biol. 2024 Mar 7. doi: 10.1161/ATVBAHA.124.320817. Online ahead of print.

PMID: 38450511 No abstract available.

 

A randomized double-blind trial of intranasal dexmedetomidine versus intranasal esketamine for procedural sedation and analgesia in young children.

Nikula A, Lundeberg S, Ryd Rinder M, Lääperi M, Sandholm K, Castrén M, Kurland L.

Scand J Trauma Resusc Emerg Med. 2024 Mar 4;32(1):16. doi: 10.1186/s13049-024-01190-5.

PMID: 38439043 

Free PMC article. Clinical Trial.

 

Consequences of Amyloid-β Deficiency for the Liver.

Buniatian GH, Schwinghammer U, Tremmel R, Cynis H, Weiss TS, Weiskirchen R, Lauschke VM, Youhanna S, Ramos I, Valcarcel M, Seferyan T, Rahfeld JU, Rieckmann V, Klein K, Buadze M, Weber V, Kolak V, Gebhardt R, Friedman SL, Müller UC, Schwab M, Danielyan L.

Adv Sci (Weinh). 2024 Mar 2:e2307734. doi: 10.1002/advs.202307734. Online ahead of print.

PMID: 38430535

 

The design of the PRINCESS 2 trial: A randomized trial to study the impact of ultrafast hypothermia on complete neurologic recovery after out-of-hospital cardiac arrest with initial shockable rhythm.

Dillenbeck E, Hollenberg J, Holzer M, Busch HJ, Nichol G, Radsel P, Belohlavec J, Torres EC, López-de-Sa E, Rosell F, Ristagno G, Forsberg S, Annoni F, Svensson L, Jonsson M, Bäckström D, Gellerfors M, Awad A, Taccone FS, Nordberg P.

Am Heart J. 2024 Feb 28;271:97-108. doi: 10.1016/j.ahj.2024.02.020. Online ahead of print.

PMID: 38417773

 

Cognitive Function and Variability in Antipsychotic Drug-Naive Patients With First-Episode Psychosis: A Systematic Review and Meta-Analysis.

Lee M, Cernvall M, Borg J, Plavén-Sigray P, Larsson C, Erhardt S, Sellgren CM, Fatouros-Bergman H, Cervenka S.

JAMA Psychiatry. 2024 Feb 28:e240016. doi: 10.1001/jamapsychiatry.2024.0016. Online ahead of print.

PMID: 38416480 

Free PMC article.

 

Lung impedance changes during awake prone positioning in COVID-19. A non-randomized cross-over study.

Rosén J, Frykholm P, Jonsson Fagerlund M, Pellegrini M, Campoccia Jalde F, von Oelreich E, Fors D.

PLoS One. 2024 Feb 21;19(2):e0299199. doi: 10.1371/journal.pone.0299199. eCollection 2024.

PMID: 38381730 

Free PMC article. Clinical Trial.

 

Early systemic insults following traumatic brain injury: association with biomarker profiles, therapy for intracranial hypertension, and neurological outcomes-an analysis of CENTER-TBI data.

Robba C, Graziano F, Picetti E, Åkerlund C, Addis A, Pastore G, Sivero M, Rebora P, Galimberti S, Stocchetti N, Maas A, Menon DK, Citerio G; CENTER-TBI Participants and Investigators.

Intensive Care Med. 2024 Feb 20. doi: 10.1007/s00134-024-07324-8. Online ahead of print.

PMID: 38376517

 

The genetic changes that shaped Neandertals, Denisovans, and modern humans.

Zeberg H, Jakobsson M, Pääbo S.

Cell. 2024 Feb 29;187(5):1047-1058. doi: 10.1016/j.cell.2023.12.029. Epub 2024 Feb 16.

PMID: 38367615 Review.

 

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model.

van Riet S, Julien A, Atanasov A, Nordling Å, Ingelman-Sundberg M.

Hepatol Commun. 2024 Feb 14;8(3):e0374. doi: 10.1097/HC9.0000000000000374. eCollection 2024 Mar 1.

PMID: 38358377

Free PMC article.

 

Cerebrospinal fluid proteomic signatures are associated with symptom severity of first-episode psychosis.

Haroon H, Ho AM, Gupta VK, Dasari S, Sellgren CM, Cervenka S, Engberg G, Eren F, Erhardt S, Sung J, Choi DS.

J Psychiatr Res. 2024 Mar;171:306-315. doi: 10.1016/j.jpsychires.2024.02.002. Epub 2024 Feb 2.

PMID: 38340697

 

The effect of heparins on plasma concentration of heparin-binding protein: a pilot study.

Halldorsdottir H, Lindbom L, Ebberyd A, Oldner A, Weitzberg E.

BJA Open. 2024 Jan 27;9:100256. doi: 10.1016/j.bjao.2023.100256. eCollection 2024 Mar.

PMID: 38318270 

Free PMC article.

 

Lower complement C1q levels in first-episode psychosis and in schizophrenia.

Koskuvi M, Malwade S, Gracias Lekander J, Hörbeck E, Bruno S, Holmen Larsson J, Pelanis A, Isgren A, Goulding A, Fatouros-Bergman H, Samudyata, Schalling M, Piehl F, Erhardt S, Landen M, Cervenka S, Orhan F, Sellgren CM.

Brain Behav Immun. 2024 Mar;117:313-319. doi: 10.1016/j.bbi.2024.01.219. Epub 2024 Feb 1.

PMID: 38301948

 

Next-generation sequencing in pharmacogenomics - fit for clinical decision support?

Zhou Y, Lauschke VM.

Expert Rev Clin Pharmacol. 2024 Mar;17(3):213-223. doi: 10.1080/17512433.2024.2307418. Epub 2024 Jan 23.

PMID: 38247431 Review.

 

Survival and Long-Term Functional Status of COVID-19 Patients Requiring Prolonged Extracorporeal Membrane Oxygenation Support.

Martínez-Martínez M, Schmidt M, Broman LM, Roncon-Albuquerque R Jr, Langouet E, Campos I, Argudo E, Domènech Vila JM, Sastre SM, Gallart E, Ferrer R, Combes A, Riera J.

Ann Am Thorac Soc. 2024 Mar;21(3):449-455. doi: 10.1513/AnnalsATS.202306-572OC.

PMID: 38134435 

Free PMC article.

 

Effect of an Individualized Lung Protective Ventilation on Lung Strain and Stress in Children Undergoing Laparoscopy: An Observational Cohort Study.

Acosta CM, Poliotto S, Abrego D, Bradley D, de Esteban S, Mir F, Ricci L, Natal M, Wallin M, Hallbäck M, Sipmann FS, Tusman G.

Anesthesiology. 2024 Mar 1;140(3):430-441. doi: 10.1097/ALN.0000000000004856.

PMID: 38064715

 

Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes: A Multi-Center Observational Cohort Study.

Fletcher-Sandersjöö A, Svedung Wettervik T, Tatter C, Tjerkaski J, Nelson DW, Maegele M, Svensson M, Lewén A, Enblad P, Bellander BM, Thelin EP.

J Neurotrauma. 2024 Mar;41(5-6):705-713. doi: 10.1089/neu.2023.0274. Epub 2023 Dec 28.

PMID: 38062766 

Free PMC article.

 

Capnodynamic end-expiratory lung volume assessment in anesthetized healthy children.

Lundquist J, Shams N, Wallin M, Hallbäck M, Lönnqvist PA, Karlsson J.

Paediatr Anaesth. 2024 Mar;34(3):251-258. doi: 10.1111/pan.14804. Epub 2023 Dec 6.

PMID: 38055609

 

Sustained PGC-1α2 or PGC-1α3 expression induces astrocyte dysfunction and degeneration.

Nunes MJ, Carvalho AN, Sá-Lemos C, Colaço M, Cervenka I, Ciraci V, Santos SG, Ribeiro MM, Castanheira M, Jannig PR, Gama MJ, Castro-Caldas M, Rodrigues CMP, Rodrigues E, Ruas JL.

Eur J Cell Biol. 2024 Mar;103(1):151377. doi: 10.1016/j.ejcb.2023.151377. Epub 2023 Nov 19.

PMID: 38006841

 

Disposition of levobupivacaine during intraoperative continuous caudal epidural analgesia in a preterm neonate.

Sipek J, Pokorna P, Sima M, Styblova J, Mixa V.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2024 Mar;168(1):81-84. doi: 10.5507/bp.2023.047. Epub 2023 Nov 22.

PMID: 37997373

 

EEG response to a high volume (1.5 mL/kg) caudal block in infants less than 3 months.

Castillo P, Vanhatalo S, Lundblad M, Blennow M, Lonnqvist PA.

Reg Anesth Pain Med. 2024 Mar 4;49(3):163-167. doi: 10.1136/rapm-2023-104452.

PMID: 37364921

 

Evidence for solanidine as a dietary CYP2D6 biomarker: Significant correlation with risperidone metabolism.

Wollmann BM, Smith RL, Kringen MK, Ingelman-Sundberg M, Molden E, Størset E.

Br J Clin Pharmacol. 2024 Mar;90(3):740-747. doi: 10.1111/bcp.15721. Epub 2023 Apr 11.

PMID: 36960588

 

Complications of Pediatric Midline Catheters: A Prospective Observational Pilot Study.

Östlund Å, Fläring U, Norberg Å, Kaiser S, Frisk T, Larsson P, Andersson A.

Anesth Analg. 2024 Mar 1;138(3):572-578. doi: 10.1213/ANE.0000000000006328. Epub 2022 Dec 12.

PMID: 36729761

Antibacterial mouthwash alters gut microbiome, reducing nutrient absorption and fat accumulation in Western diet-fed mice.

Carvalho LRRA, Boeder AM, Shimari M, Kleschyov AL, Esberg A, Johansson I, Weitzberg E, Lundberg JO, Carlstrom M.

Sci Rep. 2024 Feb 18;14(1):4025. doi: 10.1038/s41598-024-54068-y.

PMID: 38369624

 

Neurophysiological treatment effects of mesdopetam, pimavanserin and clozapine in a rodent model of Parkinson's disease psychosis.

Stan TL, Ronaghi A, Barrientos SA, Halje P, Censoni L, Garro-Martínez E, Nasretdinov A, Malinina E, Hjorth S, Svensson P, Waters S, Sahlholm K, Petersson P.

Neurotherapeutics. 2024 Feb 16:e00334. doi: 10.1016/j.neurot.2024.e00334. Online ahead of print.

PMID: 38368170

 

The genetic changes that shaped Neandertals, Denisovans, and modern humans.

Zeberg H, Jakobsson M, Pääbo S.

Cell. 2024 Feb 14:S0092-8674(23)01403-4. doi: 10.1016/j.cell.2023.12.029. Online ahead of print.

PMID: 38367615 Review.

 

Restoration of blood vessel regeneration in the era of combination SGLT2i and GLP-1RA therapy for diabetes and obesity.

Terenzi DC, Bakbak E, Teoh H, Krishnaraj A, Puar P, Rotstein OD, Cosentino F, Goldenberg RM, Verma S, Hess DA.

Cardiovasc Res. 2024 Feb 17;119(18):2858-2874. doi: 10.1093/cvr/cvae016.

PMID: 38367275

 

Preparedness for Severe Maternal Morbidity in European Hospitals: The MaCriCare Study.

Krawczyk P, Dabrowska D, Guasch E, Jörnvall H, Lucas N, Mercier FJ, Schyns-van den Berg A, Weiniger CF, Balcerzak Ł, Cantellow S; MaCriCare study group.

Anaesth Crit Care Pain Med. 2024 Feb 13:101355. doi: 10.1016/j.accpm.2024.101355. Online ahead of print.

PMID: 38360406

 

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model.

van Riet S, Julien A, Atanasov A, Nordling Å, Ingelman-Sundberg M.

Hepatol Commun. 2024 Feb 14;8(3):e0374. doi: 10.1097/HC9.0000000000000374. eCollection 2024 Mar 1.

PMID: 38358377

Free PMC article.

 

Pulmonary nitric oxide in astronauts before and during long-term spaceflight.

Karlsson LL, Gustafsson LE, Linnarsson D.

Front Physiol. 2024 Jan 31;15:1298863. doi: 10.3389/fphys.2024.1298863. eCollection 2024.

PMID: 38357501

Free PMC article.

 

Editorial: Views on JARO 2023.

Cederroth C.

J Assoc Res Otolaryngol. 2024 Feb 12. doi: 10.1007/s10162-024-00931-8. Online ahead of print.

PMID: 38345701 No abstract available.

 

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment.

Ingelman-Sundberg M, Pirmohamed M.

J Intern Med. 2024 Feb 11. doi: 10.1111/joim.13772. Online ahead of print.

PMID: 38343077 Review.

 

Cerebrospinal fluid proteomic signatures are associated with symptom severity of first-episode psychosis.

Haroon H, Ho AM, Gupta VK, Dasari S, Sellgren CM, Cervenka S, Engberg G, Eren F, Erhardt S, Sung J, Choi DS.

J Psychiatr Res. 2024 Feb 2;171:306-315. doi: 10.1016/j.jpsychires.2024.02.002. Online ahead of print.

PMID: 38340697

 

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials.

Milosavljević F, Molden PE, Ingelman-Sundberg PM, Jukić APMM.

Eur Neuropsychopharmacol. 2024 Feb 9;81:43-52. doi: 10.1016/j.euroneuro.2024.01.005. Online ahead of print.

PMID: 38340605

 

The dark sides of the GPCR tree - research progress on understudied GPCRs.

Scharf MM, Humphrys LJ, Berndt S, Di Pizio A, Lehmann J, Liebscher I, Nicoli A, Niv MY, Peri L, Schihada H, Schulte G.

Br J Pharmacol. 2024 Feb 10. doi: 10.1111/bph.16325. Online ahead of print.

PMID: 38339984 Review.

 

Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study.

Stroda A, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck Schimmer B, Spadaro S, Matute P, Ganter MT, Ovezov A, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Larmann J, Corneci D, Buggy DJ, Howell SJ, Lurati Buse G; MET-REPAIR investigators.

Br J Anaesth. 2024 Feb 8:S0007-0912(24)00012-6. doi: 10.1016/j.bja.2023.12.036. Online ahead of print.

PMID: 38336516

 

Epigenetic targets to enhance antitumor immune response through the induction of tertiary lymphoid structures.

Omotesho QA, Escamilla A, Pérez-Ruiz E, Frecha CA, Rueda-Domínguez A, Barragán I.

Front Immunol. 2024 Jan 25;15:1348156. doi: 10.3389/fimmu.2024.1348156. eCollection 2024.

PMID: 38333212

Free PMC article. Review.

 

Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study.

Roth S, M'Pembele R, Nienhaus J, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck-Schimmer B, Spadaro S, Matute P, Bolliger D, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Wulf H, Larmann J, Corneci D, Chammartin F, Howell SJ, Lurati Buse G; MET: Reevaluation for Perioperative Cardiac Risk Investigators.

Br J Anaesth. 2024 Feb 6:S0007-0912(24)00005-9. doi: 10.1016/j.bja.2024.01.003. Online ahead of print.

PMID: 38326210 No abstract available.

 

A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death.

Minnai F, Biscarini F, Esposito M, Dragani TA, Bujanda L, Rahmouni S, Alarcón-Riquelme ME, Bernardo D, Carnero-Montoro E, Buti M, Zeberg H, Asselta R, Romero-Gómez M; GEN-COVID Multicenter Study; Fernandez-Cadenas I, Fallerini C, Zguro K, Croci S, Baldassarri M, Bruttini M, Furini S, Renieri A, Colombo F.

Sci Rep. 2024 Feb 6;14(1):3000. doi: 10.1038/s41598-024-53310-x.

PMID: 38321133

Free PMC article.

 

The effect of heparins on plasma concentration of heparin-binding protein: a pilot study.

Halldorsdottir H, Lindbom L, Ebberyd A, Oldner A, Weitzberg E.

BJA Open. 2024 Jan 27;9:100256. doi: 10.1016/j.bjao.2023.100256. eCollection 2024 Mar.

PMID: 38318270

Free PMC article.

 

The therapeutic potential of galanin in the management of pain - a review article.

Hökfelt T, Wiesenfeld-Hallin Z.

Dan Med J. 2024 Jan 23;71(2):A10230653. doi: 10.61409/A10230653.

PMID: 38314733 Review.

 

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7.

Kinsolving J, Bous J, Kozielewicz P, Košenina S, Shekhani R, Grätz L, Masuyer G, Wang Y, Stenmark P, Dong M, Schulte G.

Cell Rep. 2024 Feb 1;43(2):113727. doi: 10.1016/j.celrep.2024.113727. Online ahead of print.

PMID: 38308843

 

Lower complement C1q levels in first-episode psychosis and in schizophrenia.

Koskuvi M, Malwade S, Gracias Lekander J, Hörbeck E, Bruno S, Holmen Larsson J, Pelanis A, Isgren A, Goulding A, Fatouros-Bergman H, Samudyata, Schalling M, Piehl F, Erhardt S, Landen M, Cervenka S, Orhan F, Sellgren CM.

Brain Behav Immun. 2024 Feb 1;117:313-319. doi: 10.1016/j.bbi.2024.01.219. Online ahead of print.

PMID: 38301948

 

Homo sapiens reached the higher latitudes of Europe by 45,000 years ago.

Mylopotamitaki D, Weiss M, Fewlass H, Zavala EI, Rougier H, Sümer AP, Hajdinjak M, Smith GM, Ruebens K, Sinet-Mathiot V, Pederzani S, Essel E, Harking FS, Xia H, Hansen J, Kirchner A, Lauer T, Stahlschmidt M, Hein M, Talamo S, Wacker L, Meller H, Dietl H, Orschiedt J, Olsen JV, Zeberg H, Prüfer K, Krause J, Meyer M, Welker F, McPherron SP, Schüler T, Hublin JJ.

Nature. 2024 Feb;626(7998):341-346. doi: 10.1038/s41586-023-06923-7. Epub 2024 Jan 31.

PMID: 38297117

Free PMC article.

 

Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia: recent progress on the mechanisms and interventional strategies.

Wang HL, Siow R, Schmauck-Medina T, Zhang J, Sandset PM, Filshie C, Lund Ø, Partridge L, Bergersen LH, Juel Rasmussen L, Palikaras K, Sotiropoulos I, Storm-Mathisen J, Rubinsztein DC, Spillantini MG, De Zeeuw CI, Watne LO, Vyhnalek M, Veverova K, Liang KX, Tavernarakis N, Bohr VA, Yokote K, Saarela J, Nilsen H, Gonos ES, Scheibye-Knudsen M, Chen G, Kato H, Selbæk G, Fladby T, Nilsson P, Simonsen A, Aarsland D, Lautrup S, Ottersen OP, Cox LS, Fang EF.

J Gerontol A Biol Sci Med Sci. 2024 Jan 30:glae029. doi: 10.1093/gerona/glae029. Online ahead of print.

PMID: 38289789

 

Impact of Menstrual cycle-based Periodized training on Aerobic performance, a Clinical Trial study protocol-the IMPACT study.

Ekenros L, von Rosen P, Norrbom J, Holmberg HC, Sundberg CJ, Fridén C, Hirschberg AL.

Trials. 2024 Jan 29;25(1):93. doi: 10.1186/s13063-024-07921-4.

PMID: 38287424

Free PMC article.

 

Intraocular liver spheroids for non-invasive high-resolution in vivo monitoring of liver cell function.

Lazzeri-Barcelo F, Oliva-Vilarnau N, Baniol M, Leibiger B, Bergmann O, Lauschke VM, Leibiger IB, Moruzzi N, Berggren PO.

Nat Commun. 2024 Jan 26;15(1):767. doi: 10.1038/s41467-024-45122-4.

PMID: 38278787

Free PMC article.

 

Next-generation sequencing in pharmacogenomics - fit for clinical decision support?

Zhou Y, Lauschke VM.

Expert Rev Clin Pharmacol. 2024 Jan 22:1-11. doi: 10.1080/17512433.2024.2307418. Online ahead of print.

PMID: 38247431 Review.

 

Physical activity, suicidal ideation, suicide attempt and death among individuals with mental or other medical disorders: A systematic review of observational studies.

Fabiano N, Gupta A, Wong S, Tran J, Mohammad IY, Bal S, Fiedorowicz JG, Firth J, Stubbs B, Vancampfort D, Schuch FB, Carr LJ, Shorr R, Cortese S, Manchia M, Hartman CA, Høye A, Fusar-Poli P, Koyanagi A, Vieta E, Nielsen RE, Holt RI, Correll CU, Du Rietz E, Taipale H, Lehto K, Larrson H, Nordentoft M, Dragioti E, Skonieczna-Żydecka K, Solmi M; ECNP Physical And meNtal (PAN-)Health group.

Neurosci Biobehav Rev. 2024 Jan 20;158:105547. doi: 10.1016/j.neubiorev.2024.105547. Online ahead of print.

PMID: 38246231 Review.

 

Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies.

Kammann T, Gorin JB, Parrot T, Gao Y, Ponzetta A, Emgård J, Maleki KT, Sekine T, Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S, Rooyackers O, Skagerberg M, Eriksson LI, Norrby-Teglund A, Mak JYW, Fairlie DP, Björkström NK, Klingström J, Ljunggren HG, Aleman S, Buggert M, Strålin K, Sandberg JK.

J Immunol. 2024 Feb 1;212(3):389-396. doi: 10.4049/jimmunol.2300639.

PMID: 38117799

Free PMC article.

 

Dissecting the impact of complement component 4A in bipolar disorder.

Hörbeck E, Jonsson L, Malwade S, Karlsson R, Pålsson E, Sigström R, Sellgren CM, Landén M.

Brain Behav Immun. 2024 Feb;116:150-159. doi: 10.1016/j.bbi.2023.12.006. Epub 2023 Dec 7.

PMID: 38070620

 

NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease.

Caria I, Nunes MJ, Ciraci V, Carvalho AN, Ranito C, Santos SG, Gama MJ, Castro-Caldas M, Rodrigues CMP, Ruas JL, Rodrigues E.

Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166980. doi: 10.1016/j.bbadis.2023.166980. Epub 2023 Dec 5.

PMID: 38061599

 

Dimethyl malonate preserves renal and mitochondrial functions following ischemia-reperfusion via inhibition of succinate dehydrogenase.

Carlström M, Rannier Ribeiro Antonino Carvalho L, Guimaraes D, Boeder A, Schiffer TA.

Redox Biol. 2024 Feb;69:102984. doi: 10.1016/j.redox.2023.102984. Epub 2023 Dec 5.

PMID: 38061207

Free PMC article.

 

Environmental chemicals change extracellular lipidome of mature human white adipocytes.

Burkhardt P, Palma-Duran SA, Tuck ARR, Norgren K, Li X, Nikiforova V, Griffin JL, Munic Kos V.

Chemosphere. 2024 Feb;349:140852. doi: 10.1016/j.chemosphere.2023.140852. Epub 2023 Dec 2.

PMID: 38048832

 

Acyl ghrelin increases cardiac output while preserving right ventricular-pulmonary arterial coupling in heart failure.

Erhardsson M, Faxén UL, Venkateshvaran A, Hage C, Pironti G, Thorvaldsen T, Webb DL, Hellström PM, Andersson DC, Ståhlberg M, Lund LH.

ESC Heart Fail. 2024 Feb;11(1):601-605. doi: 10.1002/ehf2.14580. Epub 2023 Nov 29.

PMID: 38030138

Free PMC article. Clinical Trial.

 

What is the Current Clinical Impact of the CYP2CTG Haplotype?

Ingelman-Sundberg M, Jukic M, Bråten LS, Kringen MK, Molden E.

Clin Pharmacol Ther. 2024 Feb;115(2):183. doi: 10.1002/cpt.3094. Epub 2023 Nov 20.

PMID: 37984075 No abstract available.

 

Anticoagulation and Bleeding during Veno-Venous Extracorporeal Membrane Oxygenation: Insights from the PROTECMO Study.

Martucci G, Giani M, Schmidt M, Tanaka K, Tabatabai A, Tuzzolino F, Agerstrand C, Riera J, Ramanan R, Grasselli G, Ait Hssain A, Gannon WD, Buabbas S, Gorjup V, Trethowan B, Rizzo M, Fanelli V, Jeon K, De Pascale G, Combes A, Ranieri MV, Duburcq T, Foti G, Chico JI, Balik M, Broman LM, Schellongowski P, Buscher H, Lorusso R, Brodie D, Arcadipane A; International ECMO Network (ECMONet).

Am J Respir Crit Care Med. 2024 Feb 15;209(4):417-426. doi: 10.1164/rccm.202305-0896OC.

PMID: 37943110

 

Multivalent insulin receptor activation using insulin-DNA origami nanostructures.

Spratt J, Dias JM, Kolonelou C, Kiriako G, Engström E, Petrova E, Karampelias C, Cervenka I, Papanicolaou N, Lentini A, Reinius B, Andersson O, Ambrosetti E, Ruas JL, Teixeira AI.

Nat Nanotechnol. 2024 Feb;19(2):237-245. doi: 10.1038/s41565-023-01507-y. Epub 2023 Oct 9.

PMID: 37813939

Free PMC article.

 

Pharmacogenomics Beyond Single Common Genetic Variants: The Way Forward.

Lauschke VM, Zhou Y, Ingelman-Sundberg M.

Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:33-51. doi: 10.1146/annurev-pharmtox-051921-091209. Epub 2023 Jul 28.

PMID: 37506333 Review.

CD163+ macrophages monitor enhanced permeability at the blood-dorsal root ganglion barrier. 

Lund H, Hunt MA, Kurtović Z, Sandor K, Kägy PB, Fereydouni N, Julien A, Göritz C, Vazquez-Liebanas E, Andaloussi Mäe M, Jurczak A, Han J, Zhu K, Harris RA, Lampa J, Graversen JH, Etzerodt A, Haglund L, Yaksh TL, Svensson CI. 

J Exp Med. 2024 Feb 5;221(2):e20230675. doi: 10.1084/jem.20230675. Epub 2023 Dec 20. PMID: 38117255 

Free PMC article. 

 

Influenza-associated invasive aspergillosis in patients admitted to the intensive care unit in Sweden: a prospective multicentre cohort study. 

Krifors A, Blennow O, Påhlman LI, Gille-Johnson P, Janols H, Lipcsey M, Källman J, Tham J, Stjärne Aspelund A, Ljungquist O, Hammarskjöld F, Hällgren A, De Geer L, Lemberg M, Petersson J, Castegren M. 

Infect Dis (Lond). 2024 Feb;56(2):110-115. doi: 10.1080/23744235.2023.2273381. Epub 2023 Dec 18. PMID: 37897800 

 

Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training. 

Emanuelsson EB, Arif M, Reitzner SM, Perez S, Lindholm ME, Mardinoglu A, Daub C, Sundberg CJ, Chapman MA. 

iScience. 2023 Dec 5;27(1):108638. doi: 10.1016/j.isci.2023.108638. eCollection 2024 Jan 19. PMID: 38213622  

Free PMC article. 

 

A Microfluidic High-Capacity Screening Platform for Neurological Disorders. 

Moll L, Pihl J, Karlsson M, Karila P, Svensson CI. 

ACS Chem Neurosci. 2024 Jan 17;15(2):236-244. doi: 10.1021/acschemneuro.3c00409. Epub 2023 Dec 27. PMID: 38150531 

 

Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model. 

Redenšek Trampuž S, van Riet S, Nordling Å, Ingelman-Sundberg M. 

Sci Rep. 2024 Jan 16;14(1):1396. doi: 10.1038/s41598-023-49240-9. PMID: 38228622  

Free PMC article. 

 

The success rate and complications of midline catheters in pediatric outpatient parenteral antibiotic therapy (OPAT). 

Fläring U, Lundevall H, Norberg Å, Andersson A. 

Eur J Pediatr. 2024 Jan 16. doi: 10.1007/s00431-024-05432-7. Online ahead of print. PMID: 38227054 

 

Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M. 

Dollet L, Lundell LS, Chibalin AV, Pendergrast LA, Pillon NJ, Lansbury EL, Elmastas M, Frendo-Cumbo S, Jalkanen J, de Castro Barbosa T, Cervone DT, Caidahl K, Dmytriyeva O, Deshmukh AS, Barrès R, Rydén M, Wallberg-Henriksson H, Zierath JR, Krook A. 

Cell Rep Med. 2024 Jan 16;5(1):101348. doi: 10.1016/j.xcrm.2023.101348. Epub 2023 Dec 26. PMID: 38151020 

 

Incidence and risk factors of peri-operative stroke in major non-cardiovascular, non-neurologic surgery-A retrospective register-based cohort study. 

Falck-Jones R, Bell M, Hallqvist L. 

Acta Anaesthesiol Scand. 2024 Jan 11. doi: 10.1111/aas.14373. Online ahead of print. PMID: 38212290 

 

Outcomes of SARS-CoV-2 infection in early pregnancy-A systematic review and meta-analysis. 

Rodriguez-Wallberg KA, Nilsson HP, Røthe EB, Zhao A, Shah PS, Acharya G. 

Acta Obstet Gynecol Scand. 2024 Jan 10. doi: 10.1111/aogs.14764. Online ahead of print. PMID: 38200686 Review. 

 

Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice. 

de Assis LVM, Harder L, Lacerda JT, Parsons R, Kaehler M, Cascorbi I, Nagel I, Rawashdeh O, Mittag J, Oster H. 

Sci Rep. 2024 Jan 5;14(1):640. doi: 10.1038/s41598-023-50374-z. PMID: 38182610  

Free PMC article. 

 

Adverse Events of Peripherally Administered Norepinephrine During Surgery: A Prospective Multicenter Study. 

Christensen J, Andersson E, Sjöberg F, Hellgren E, Harbut P, Harbut J, Sjövall F, von Bruhn Gufler C, Mårtensson J, Rubenson Wahlin R, Joelsson-Alm E, Cronhjort M. 

Anesth Analg. 2024 Jan 5. doi: 10.1213/ANE.0000000000006806. Online ahead of print. PMID: 38180886 

 

Opioid use following cardio-thoracic intensive care: risk factors and outcomes: a cohort study. 

von Oelreich E, Campoccia Jalde F, Rysz S, Eriksson J. 

Sci Rep. 2024 Jan 2;14(1):20. doi: 10.1038/s41598-023-50508-3. PMID: 38168129  

Free PMC article. 

 

Association of Preoperative Renal-Resistive Index With Long-term Renal and Cardiovascular Outcomes After Cardiac Surgery. 

Renberg M, Sartipy U, Bell M, Hertzberg D. 

J Cardiothorac Vasc Anesth. 2024 Jan;38(1):101-108. doi: 10.1053/j.jvca.2023.10.035. Epub 2023 Oct 28. PMID: 38052689 

 

Coordinated Regulation of Myonuclear DNA Methylation, mRNA, and miRNA Levels Associates With the Metabolic Response to Rapid Synergist Ablation-Induced Skeletal Muscle Hypertrophy in Female Mice. 

Ismaeel A, Thomas NT, McCashland M, Vechetti IJ, Edman S, Lanner JT, Figueiredo VC, Fry CS, McCarthy JJ, Wen Y, Murach KA, von Walden F. 

Function (Oxf). 2023 Nov 6;5(1):zqad062. doi: 10.1093/function/zqad062. eCollection 2024. PMID: 38020067  

Free PMC article. 

 

Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis. 

Ren L, Charbord J, Chu L, Kemas AM, Bertuzzi M, Mi J, Xing C, Lauschke VM, Andersson O. 

Diabetologia. 2024 Jan;67(1):137-155. doi: 10.1007/s00125-023-06020-4. Epub 2023 Oct 16. PMID: 37843554  

Free PMC article. 

 

CT-based volumetric measures obtained through deep learning: Association with biomarkers of neurodegeneration. 

Srikrishna M, Ashton NJ, Moscoso A, Pereira JB, Heckemann RA, van Westen D, Volpe G, Simrén J, Zettergren A, Kern S, Wahlund LO, Gyanwali B, Hilal S, Ruifen JC, Zetterberg H, Blennow K, Westman E, Chen C, Skoog I, Schöll M. 

Alzheimers Dement. 2024 Jan;20(1):629-640. doi: 10.1002/alz.13445. Epub 2023 Sep 28. PMID: 37767905 

 

Trends in Incidence and Outcomes of Cardiac Arrest Occurring in Swedish ICUs. 

Flam B, Andersson Franko M, Skrifvars MB, Djärv T, Cronhjort M, Jonsson Fagerlund M, Mårtensson J. 

Crit Care Med. 2024 Jan 1;52(1):e11-e20. doi: 10.1097/CCM.0000000000006067. Epub 2023 Sep 25. PMID: 37747306 

 

A Plea for Adoption of the Common ECLS Nomenclature. 

Brewer JM, Broman LM, Maybauer MO. 

ASAIO J. 2024 Jan 1;70(1):e16. doi: 10.1097/MAT.0000000000002040. Epub 2023 Aug 30. PMID: 37651629 No abstract available. 

 

Fascial plane blocks in children-Scientifically supported or not? 

Lönnqvist PA. 

Paediatr Anaesth. 2024 Jan;34(1):13-18. doi: 10.1111/pan.14752. Epub 2023 Aug 31. PMID: 37650686 

 

Determinants of Frame Running Capacity in Athletes With Cerebral Palsy to Improve Training Routines and Classification Strategies: A Cross-sectional Observational Study. 

Hjalmarsson E, Lidbeck C, Barrero Santiago L, Pingel J, Norrbom J, Sanz G, Palmcrantz A, Pontén E, von Walden F, Fernandez-Gonzalo R. 

Am J Phys Med Rehabil. 2024 Jan 1;103(1):79-86. doi: 10.1097/PHM.0000000000002233. Epub 2023 Mar 7. PMID: 36897812 

 

Unraveling the role of Slc10a4 in auditory processing and sensory motor gating: Implications for neuropsychiatric disorders? 

Ciralli B, Malfatti T, Hilscher MM, Leao RN, Cederroth CR, Leao KE, Kullander K. 

Prog Neuropsychopharmacol Biol Psychiatry. 2023 Dec 30;131:110930. doi: 10.1016/j.pnpbp.2023.110930. Online ahead of print. PMID: 38160852 

 

Exercise induces tissue-specific adaptations to enhance cardiometabolic health. 

Ashcroft SP, Stocks B, Egan B, Zierath JR. 

Cell Metab. 2023 Dec 29:S1550-4131(23)00459-X. doi: 10.1016/j.cmet.2023.12.008. Online ahead of print. PMID: 38183980 Review. 

 

Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" NeuroToxicology 83 (2021) 1-13. 

Costa G, Spulber S, Paci E, Antonietta Casu M, Ceccatelli S, Simola N, Morelli M. 

Neurotoxicology. 2023 Dec 23:S0161-813X(23)00185-7. doi:10.1016/j.neuro.2023.12.014. Online ahead of print. PMID: 38143152 No abstract available. 

 

Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biology approach. 

Reitzner SM, Emanuelsson EB, Arif M, Kaczkowski B, Kwon AT, Mardinoglu A, Arner E, Chapman MA, Sundberg CJ. 

Mol Metab. 2023 Dec 21;79:101857. doi: 10.1016/j.molmet.2023.101857. Online ahead of print. PMID: 38141850 

 

Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" [NeuroToxicology, 83 (2021), 1-13]. 

Costa G, Spulber S, Paci E, Casu MA, Ceccatelli S, Simola N, Morelli M. 

Neurotoxicology. 2023 Dec 21:S0161-813X(23)00181-X. doi:10.1016/j.neuro.2023.12.010. Online ahead of print. PMID: 38135581 No abstract available. 

 

Pre-oxygenation using high-flow nasal oxygen versus tight facemask in trauma patients undergoing emergency anaesthesia. 

Sjöblom A, Hedberg M, Gille A, Guerra A, Aanesen V, Forsberg IM, Fagerlund MJ. 

Acta Anaesthesiol Scand. 2023 Dec 21. doi: 10.1111/aas.14368. Online ahead of print. PMID: 38129931 

 

Correction: Perioperative water and electrolyte balance and water homeostasis regulation in children with acute surgery. 

Roberts DN, Vallén P, Cronhjort M, Alfvén T, Sandblom G, Törnroth-Horsefield S, Jensen BL, Lönnqvist PA, Frithiof R, Carlström M, Krmar RT. 

Pediatr Res. 2023 Dec 19. doi: 10.1038/s41390-023-02975-7. Online ahead of print. PMID: 38114610 No abstract available. 

 

Circulating immune cell populations at rest and in response to acute endurance exercise in young adults with cerebral palsy. 

Kruse A, Imery I, Corell L, Hjalmarsson E, Fernandez-Gonzalo R, Von Walden F, Reitzner SM. 

Dev Med Child Neurol. 2023 Dec 18. doi: 10.1111/dmcn.15835. Online ahead of print. PMID: 38111130 

 

Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase. 

Stadhouders LEM, Smith JAB, Gabriel BM, Verbrugge SAJ, Hammersen TD, Kolijn D, Vogel ISP, Mohamed AD, de Wit GMJ, Offringa C, Hoogaars WMH, Gehlert S, Wackerhage H, Jaspers RT. 

Exp Cell Res. 2023 Dec 15;433(2):113820. doi: 10.1016/j.yexcr.2023.113820. Epub 2023 Oct 23. PMID: 37879549 

 

Neural tube-associated boundary caps are a major source of mural cells in the skin. 

Gerschenfeld G, Coulpier F, Gresset A, Pulh P, Job B, Topilko T, Siegenthaler J, Kastriti ME, Brunet I, Charnay P, Topilko P. 

Elife. 2023 Dec 14;12:e69413. doi: 10.7554/eLife.69413. PMID: 38095361  

Free PMC article. 

 

Analysis of Sprint Ski Mountaineering Performance. 

Fornasiero A, Fornoni S, Callovini A, Todesco B, Savoldelli A, Schena F, Holmberg HC, Pellegrini B, Bortolan L. 

Int J Sports Physiol Perform. 2023 Dec 12:1-9. doi: 10.1123/ijspp.2023-0075. Online ahead of print. PMID: 38086366 

 

Aerobic exercise training mitigates tumor growth and cancer-induced splenomegaly through modulation of non-platelet platelet factor 4 expression. 

Tobias GC, Gomes JLP, Fernandes LG, Voltarelli VA, de Almeida NR, Jannig PR, de Souza RWA, Negrão CE, Oliveira EM, Chammas R, Alves CRR, Brum PC. 

Sci Rep. 2023 Dec 11;13(1):21970. doi: 10.1038/s41598-023-47217-2. PMID: 38081853  

Free PMC article. 

 

Modulation of the capillary leakage by exogenous albumin in a rat model of endothelial glycocalyx damage. 

Astapenko D, Zrzavecky M, Gorskaja D, Hyspler R, Ticha A, Radochova V, Lehmann C, Malbrain MLNG, Cerny V, Hahn RG. 

Clin Hemorheol Microcirc. 2023 Dec 7. doi: 10.3233/CH-232027. Online ahead of print. PMID: 38073383 

 

Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse. 

Kurt Z, Cheng J, Barrere-Cain R, McQuillen CN, Saleem Z, Hsu N, Jiang N, Pan C, Franzén O, Koplev S, Wang S, Björkegren J, Lusis AJ, Blencowe M, Yang X. 

Elife. 2023 Dec 7;12:RP88266. doi: 10.7554/eLife.88266. PMID: 38060277  

Free PMC article. 

 

Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization. 

Ge R, Yu Y, Qi YX, Fan YV, Chen S, Gao C, Haas SS, Modabbernia A, New F, Agartz I, Asherson P, Ayesa-Arriola R, Banaj N, Banaschewski T, Baumeister S, Bertolino A, Boomsma DI, Borgwardt S, Bourque J, Brandeis D, Breier A, Brodaty H, Brouwer RM, Buckner R, Buitelaar JK, Cannon DM, Caseras X, Cervenka S, Conrod PJ, Crespo-Facorro B, Crivello F, Crone EA, de Haan L, de Zubicaray GI, Di Giorgio A, Erk S, Fisher SE, Franke B, Frodl T, Glahn DC, Grotegerd D, Gruber O, Gruner P, Gur RE, Gur RC, Harrison BJ, Hatton SN, Hickie I, Howells FM, Pol HEH, Huyser C, Jernigan TL, Jiang J, Joska JA, Kahn RS, Kalnin AJ, Kochan NA, Koops S, Kuntsi J, Lagopoulos J, Lazaro L, Lebedeva IS, Lochner C, Martin NG, Mazoyer B, McDonald BC, McDonald C, McMahon KL, Nakao T, Nyberg L, Piras F, Portella MJ, Qiu J, Roffman JL, Sachdev PS, Sanford N, Satterthwaite TD, Saykin AJ, Schumann G, Sellgren CM, Sim K, Smoller JW, Soares J, Sommer IE, Spalletta G, Stein DJ, Tamnes CK, Thomopolous SI, Tomyshev AS, Tordesillas-Gutiérrez D, Trollor JN, van 't Ent D, van den Heuvel OA, van Erp TG, van Haren NE, Vecchio D, Veltman DJ, Walter H, Wang Y, Weber B, Wei D, Wen W, Westlye LT, Wierenga LM, Williams SC, Wright MJ, Medland S, Wu MJ, Yu K, Jahanshad N, Thompson PM, Frangou S. 

bioRxiv. 2023 Dec 2:2023.01.30.523509. doi: 10.1101/2023.01.30.523509. Preprint. PMID: 38076938  

Free PMC article. 

 

A mouse model of sleep disorders in Parkinson's disease showing distinct effects of dopamine D2-like receptor activation. 

Medeiros DC, Plewnia C, Mendes RV, Pisanò CA, Boi L, Moraes MFD, Aguiar CL, Fisone G. 

Prog Neurobiol. 2023 Dec;231:102536. doi: 10.1016/j.pneurobio.2023.102536. Epub 2023 Oct 5. PMID: 37805096 

 

Sex Differences in Long-term Outcome of Prenatal Exposure to Excess Glucocorticoids-Implications for Development of Psychiatric Disorders. 

Elberling F, Spulber S, Bose R, Keung HY, Ahola V, Zheng Z, Ceccatelli S. 

Mol Neurobiol. 2023 Dec;60(12):7346-7361. doi: 10.1007/s12035-023-03522-5. Epub 2023 Aug 10. PMID: 37561236  

Free PMC article. 

 

Comparing the Blood Response to Hyperbaric Oxygen with High-Intensity Interval Training-A Crossover Study in Healthy Volunteers. 

Kjellberg A, Lindholm ME, Zheng X, Liwenborg L, Rodriguez-Wallberg KA, Catrina SB, Lindholm P. 

Antioxidants (Basel). 2023 Nov 25;12(12):2043. doi: 10.3390/antiox12122043. PMID: 38136163  

Free PMC article. 

 

Neuropathy with Cerebral Features Induced by Nitrous Oxide Abuse-A Case Report. 

Lindeman E, Melin S, Paucar M, Ågren R. 

Toxics. 2023 Nov 25;11(12):959. doi: 10.3390/toxics11120959. PMID: 38133360  

Free PMC article.