Neurodegeneration/Neurobiology - Break out session, KI-Mayo Meeting 2023

        Session 1 - Amyotrophic Lateral Sclerosis

• 9.00am/16.00pm: Elucidating Pathological Mechanisms in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration: Insights from TDP-43 Accumulation and VAT1L Expressing Neuronal Depletion
  Diana Vera-Garcia (MCF) 
   
• 9.10am/16.10pm: Harmonization of single-nuclei and bulk RNA-sequencing data for the characterization of induced pluripotent stem cell-derived motor neuron models in sporadic and C9orf72-associated amyotrophic lateral sclerosis (ALS)
  Mariah Hoffman (MCF)
   
• 9.20am/16.20pm: Identification of ALS risk factors leading to CHIP-related Epi-age acceleration
  Andre Teixeira da Silva Hucke (MCF)
   
• 9.30am/16.30pm:The role of osteopontin in ALS neurodegeneration, - a prognostic
  biomarker or a therapeutic target?
  Sebastian Lewandowski (KI) - Virtual
   
• 9.40am/16.40pm: Break
  
  Session 2 – Alpha-synuclein/Lewy body Disease 
   
• 9.50am/16.50pm:Presence of Alpha-Synuclein Oligomers in Parkinson's Disease with LRRK2 Mutations regardless of Lewy-related Pathology
  Hiro Sekiya (MCF)
   
• 10.00am/17.00pm: Decoding the Genomic Landscape of Mitochondrial DNA in Early-Onset Parkinson’s Disease through Long-Read Sequencing
  Ngan Tran (MCF) - Virtual
   
• 10.10am/17.10pm: Neurodegeneration in dementia with Lewy bodies – 5 years of Mayo-KI collaboration
  Annegret Habich (KI) - Virtual
   
• 10.20am/17.20pm: Abnormal levels of Alzheimer’s disease biomarkers in plasma can be detected starting from prodromal stages of dementia with Lewy bodies
  Patricia Diaz-Galvin (MC)
   
• 10.30am/17.30pm: Automated Analysis of REM Sleep without Atonia in the Lewy Body Disease Spectrum
  Emma Strainis (MC)
   
• 10.40am/17.40pm: Presenting Clinical Profiles and Phenoconversion in Women and Men with Isolated REM Sleep Behavior Disorder: A Retrospective Cohort Study Analyzing Influences of Age, Sex, Antidepressant Use, and Psychiatric Co-morbidity
  Christina Alexandres (MC)
   
• 19:00pm/12:00am: Murdock Lectur

         Session 3 – White Matter

• 8.00am/15.00pm: Meningeal lymphatic drainage regulates oligodendrocytes survival and brain myelination
  Sofia Neves (MCF)
   
• 8.10am/15.10pm: Cervical spinal cord atrophy: Brain MRI versus cervical spinal cord MRI
  Jiye Son (MC)
   
• 8.20am/15.20pm: Non-imaging indicators to capture variability in white matter changes underlying VCID
  Sheelakumari Raghavan (MC)
   
• 8.30am/15.30pm: Higher systolic and diastolic blood pressures in recently postmenopausal women are associated with greater WMH more than a decade later in the KEEPS Continuation
  Firat Kara (MC)
   
• Break
   
• 8.50am/15.50pm: Longitudinal default mode sub-networks in the language and visual variants of Alzheimer’s disease
  Irene Sintini (MC) - Virtual
   
• 9:00am/16.00pm:Longitudinal handwriting changes in patients with Primary Progressive Apraxia of Speech
  Gabriela Meade (MC) - Virutal
   
• 9.10am/ 16.10pm: A prospective clinical study on the mechanisms underlying critical illness myopathy—A time-course approach
  Lars Larsson (KI)
   
• 9.20am/ 16.20pm: Cervical vestibular evoked myogenic potentials in 3-month-old infants: Comparative characteristics and feasibility for infant vestibular screening
  Maoli Duan (KI)
   
• Break
   
• Session 5 – Amyloid and Tau
   
• 9.40am/ 16.40pm: On fitting the Jack model
  Terry Therneau (MC in Sweden) - Virtual
   
• 9.50am/ 16.50pm: Continuous associations between remote self-administered cognitive measures and amyloid and tau PET biomarkers of Alzheimer’s disease
  Logan Monahan (MC)
   
• 10.00am/ 17.00pm: Moderate ethanol exposure ameliorates cognitive function through the reduction of low-density lipoprotein cholesterol, pro-inflammatory cytokines, and Aβ deposition in early-stage of APP/PS1 mice
  Shinwoo Kang (MC)
   
• 10.10am/ 17.10pm: Oligomer Formation by Amyloid-β42 in a Membrane - Mimicking Environment in Alzheimer’s Disease
  Terry Rosenberry (MCF) - Virtual
   
• 10.20am/ 17.20pm: Chronic and sustained effects of anti-amyloid immunotherapy on plaques, microglia, and neuritic dystrophy
  Mika Cadiz (MC) - Virtual

• 18:15pm/11:15am: Lunch

• 19:00pm/12:00am: Plenary session