Publications 2016

Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy.
Haack T, Ignatius E, Calvo-Garrido J, Iuso A, Isohanni P, Maffezzini C, et al
Am. J. Hum. Genet. 2016 09;99(3):735-743
Ciliary dyslexia candidate genes DYX1C1 and DCDC2 are regulated by Regulatory Factor X (RFX) transcription factors through X-box promoter motifs.
Tammimies K, Bieder A, Lauter G, Sugiaman-Trapman D, Torchet R, Hokkanen M, et al
FASEB J. 2016 10;30(10):3578-3587
Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.
Blaas L, Pucci F, Messal H, Andersson A, Josue Ruiz E, Gerling M, et al
Nat. Cell Biol. 2016 Dec;18(12):1346-1356
Detection and signal amplification in zebrafish RNA FISH.
Hauptmann G, Lauter G, Söll I
Methods 2016 Apr;98():50-59
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Gerling M, Büller N, Kirn L, Joost S, Frings O, Englert B, et al
Nat Commun 2016 08;7():12321
Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity.
Joost S, Zeisel A, Jacob T, Sun X, La Manno G, Lönnerberg P, et al
Cell Syst 2016 09;3(3):221-237.e9
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Segerstolpe , Palasantza A, Eliasson P, Andersson E, Andréasson A, Sun X, et al
Cell Metab. 2016 10;24(4):593-607
An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes.
Shafqat-Abbasi H, Kowalewski J, Kiss A, Gong X, Hernandez-Varas P, Berge U, et al
Elife 2016 Jan;5():e11384
The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.
Jouhilahti E, Madissoon E, Vesterlund L, Töhönen V, Krjutškov K, Plaza Reyes A, et al
Development 2016 10;143(19):3459-3469
Regulating retrotransposon activity through the use of alternative transcription start sites.
Persson J, Steglich B, Smialowska A, Boyd M, Bornholdt J, Andersson R, et al
EMBO Rep. 2016 05;17(5):753-68
Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos.
Petropoulos S, Edsgärd D, Reinius B, Deng Q, Panula S, Codeluppi S, et al
Cell 2016 May;165(4):1012-26
Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse.
Schedin-Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L
Acta Neuropathol Commun 2016 Mar;4():29
Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model.
Plaza Reyes A, Petrus-Reurer S, Antonsson L, Stenfelt S, Bartuma H, Panula S, et al
Stem Cell Reports 2016 Jan;6(1):9-17
VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity.
Marshall M, Pattu V, Halimani M, Maier-Peuschel M, Müller M, Becherer U, et al
J. Cell Biol. 2015 Jul;210(1):135-51
Tissue-infiltrating neutrophils represent the main source of IL-23 in the colon of patients with IBD.
Kvedaraite E, Lourda M, Ideström M, Chen P, Olsson-Åkefeldt S, Forkel M, et al
Gut 2016 10;65(10):1632-41