Services & Prices
KI Biobank provides services for collection, handling, storage and traceability of research samples. We make sure that the samples are stored safely and that every tube is traceable. Upon demand from the principal investigator of the study we withdraw the requested samples and send them to the collaborating laboratory for analyses.
Starting a new biobank study
At the start of a new sample collection we help you with legal and ethical aspects, such as ethical application, consent and donor information. We have many years’ experience of pre-analytic sample handling and can give advice on what samples should be taken and how they should be handled for your specific research project. Contact us in good time before the planned starting date. We need approximately four weeks to set up the study and integrate it into our automated or manual processes. For more information contact our coordinator.
KI Biobank offers both manual and automated sample handling including centrifugation, aliquotation, DNA-extraction and DNA-normalization. Furthermore, we provide service for transfer of DNA to 96-well plate formats and transfer of historical samples collections to more modern (2D-barcoded) microtubes.
KI Biobank performs automated DNA extraction from blood and saliva.
Long-term storage at KI Biobank is done in -20°C and -80°C freezers and in liquid nitrogen tanks at -190ºC. Temperature control during sample handling and long-term storage is of vital importance. It determines how the samples will perform in future analyses. The freezers have back-up electricity power and a controlled environment, including cooling and a web based alarm system. If a large temperature change occurs in freezers or in nitrogen tanks staff will be alerted and take action.
All samples stored at KI Biobank are labelled with unique barcodes. Each barcode is linked to a code key associated in a secure way with the donor. KI Biobank provides barcodes via referrals and labels.
Referrals and scanning of data
KI Biobank designs study specific referrals which create a secure connection between the study donor and the samples. Upon arrival of referrals and samples at the sample reception the referral is scanned and the data is stored in the Laboratory Information Management System (LIMS). Files (csv) with referral data are created daily and can be accessed by authorized users from the Customer-FTP server. There you can also find files (pdf) of the scanned referrals. During active sample collection referrals are ordered via e-mail to firstname.lastname@example.org. State the study name, type of referrals, number of referrals and delivery address. Referrals are usually delivered within 3-5 days.
KI Biobank prints barcode labels. These can be ordered via e-mail to email@example.com. State the name of the study, label type, number of labels and delivery address. Labels are usually delivered within 3-5 days. Labels for frozen samples are delivered within 10 days.
KI Biobank provides the system ELSA (External Logging of Sample Application) for external registration of samples labelled with barcodes. The system can be used for historical sample collections or if you don’t want to use referrals. After registration in ELSA the samples are delivered to KI Biobank and stored.
SCARAB-LIMS is a flexible system which keeps track of samples and data. The system can easily be adapted to researchers’ specific demands for their research projects.
KI Biobank is a research biobank where samples are collected for a specific research purpose. We are working according to the principle that the researcher who collects the samples also decides what the samples should be used for. This means that KI Biobank won’t release samples without the approval of the responsible researcher. In the register at BBMRI.se you can find all the sample collections at KI Biobank. If you are interested in a sample collection, please contact either the principal investigator and initiate collaboration or ask us to help you. When you have agreed on which samples to withdraw, we help you to pick out the samples and deliver them in the required format.
To pick out samples from your sample collection fill in the form Withdrawal Order (Withdrawal Order REMP if the samples are in REMP tubes). You should also prepare an Excel file with Sample donor ID. The sample donor ID can be one of two types, either CDK (Customer Donor Key) or RID (Referral ID). The order form and the Excel file should be sent via e-mail to firstname.lastname@example.org, and also a paper copy with the signature of the principal investigator via ordinary mail to KI Biobank, MEB, Karolinska Institutet, Box 281, SE-171 77 Stockholm.
If your samples should be analyzed outside Karolinska Institutet you need to have a Material Transfer Agreement (MTA), signed by the receiving laboratory and the head of KI Biobank.
KI Biobank also stores data collected in research studies. If you want to withdraw data you need to fill in the form Data Withdrawal Order. Attach a list of variables, a Data Transfer Agreement (DTA) and an ethical approval. These should be sent via e-mail to email@example.com.