Richard Ågren

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF NEUROSURGERY. 2026;144(4):857-867
Cranioplasty outcomes after decompressive craniectomy: a near-nationwide population-based study based on 15 years of cranial reconstructions in Sweden
Holmgren K; Fjellborg M; Nilsson RF; Lindvall P; Corell A; Harba D; Fletcher-Sandersjoo A; Birgersson U; Saemundsson B; Agren R; Linder LKB; Sundblom J; Ryttlefors M; Wettervik TS
Article: WORLD NEUROSURGERY. 2026;210:124941
Malignant Middle Cerebral Artery Infarction Decompressive Craniectomy Score: A Prognostic Model for Malignant Middle Cerebral Artery Infarction Patients Treated with Decompressive Craniectomy
Alhamdan M; Corell A; Holmgren K; Muncan E; Lindvall P; Saemundsson B; Nilsson R; Enblad P; Hanell A; Agren R; Fletcher-Sandersjoo A; Wettervik TS
Article: JOURNAL OF NEUROSURGERY. 2026;144(3):590-599
Cranioplasty after surgical site infection in brain tumor patients: insights from a 15-year Swedish multicenter study
Holmgren K; Fletcher-Sandersjoo A; Saemundsson B; Linder LKB; Nilsson R; Agren R; Sundblom J; Latini F; Lindvall P; Muncan E; Corell A; Wettervik TS
Article: SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE. 2026;34(1):51
Decompressive craniectomy in traumatic brain injury: insights from a 15-year multicentre cohort in Sweden
Leal-Mendez F; Holmgren K; Corell A; Nesic T; Lindvall P; Saemundsson B; Nilsson R; Enblad P; Velle F; Lewen A; Agren R; Fletcher-Sandersjoo A; Svedung-Wettervik T
Article: REDOX BIOLOGY. 2026;89:103955
The sodium/iodide symporter is a nitrate transporter in the human salivary gland
Picozzi G; Westerberg LJS; Jurga J; Zeberg H; Nihlen C; Pernow J; Carlstrom M; Weitzberg E; Agren R; Lundberg JO
Article: WORLD NEUROSURGERY. 2026;206:124761
Indications, Timing, and Outcome of Decompressive Craniectomy in Malignant Middle Cerebral Artery Infarction: A Swedish Multicenter Study
Alhamdan M; Corell A; Holmgren K; Muncan E; Lindvall P; Koskinen L-O; Saemundsson B; Nilsson R; Enblad P; Agren R; Fletcher-Sandersjoo A; Wettervik TS
Article: BMC NEUROLOGY. 2026;26(1):131
Pitolisant-associated mania - a case report
Zoltek M; Agren R
Article: NEUROSURGERY. 2026
Sequencing of Cranioplasty and Shunt Surgery After Decompressive Craniectomy: A Swedish Multicenter Study.
Holmgren K; Fletcher-Sandersjöö A; Sæmundsson B; Nilsson R; Ågren R; Lindvall P; Bark D; Vedung F; Corell A; Svedung Wettervik T
Article: BRITISH JOURNAL OF NEUROSURGERY. 2026;:1-11
Decompressive craniectomy for severe cerebral venous sinus thrombosis: a 15-year Swedish multicentre case-series
Alhamdan M; Corell A; Holmgren K; Lindvall P; Agren R; Saemundsson B; Nilsson R; Leijonmarck C; Donardi R; Kevci R; Enblad P; Fletcher-Sandersjoo A; Svedung Wettervik T
Article: BRITISH JOURNAL OF NEUROSURGERY. 2026;:1-11
Decompressive craniectomy for intracerebral haemorrhage in contemporary practice: a Swedish, multi-centre study of utilization, indications, and outcomes
Holmgren K; Corell A; Sunila M; Enblad P; Fahlstrom A; Lindvall P; Leijonmarck C; Donardi R; Saemundsson B; Agren R; Nilsson R; Fletcher-Sandersjoo A; Wettervik TS
Article: SCIENCE SIGNALING. 2025;18(915):eadt8890
GNAI1 missense mutations associated with a neurodevelopmental syndrome modify Gα_i1 function
Fritsche M; Picozzi G; Nyman T; Zeberg H; Agren R
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2025;28(11):pyaf076
Partial agonist antipsychotic drugs differentially interact with a secondary binding site at the dopamine D₂ receptor
Agren R; Sahlholm K
Article: MOLECULAR BIOLOGY AND EVOLUTION. 2025;42(10):msaf243
Natural Selection of a Virus-Protective FUT2 Variant Following the Transition to Agriculture
Nordgren J; Agren R; Hu DZ; Neijd M; Childebayeva A; Prufer K; Hagbom M; Svensson L; Zeberg H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2025;122(32):e2508540122
The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior
Ju X-C; Lee S-Y; Agren R; Machado LC; Xing J; Azama C; Roy MC; Endo T; Huttner W; Siepel A; Fukunaga I; Zeberg H; Paabo S
Article: ACTA NEUROPSYCHIATRICA. 2025;37:e65
Attention-deficit hyperactivity disorder drug search trends: a Scandinavian perspective
Zoltek M; Agren R
Article: NEURO-ONCOLOGY ADVANCES. 2025;7(1):vdaf185
ONC206 as a low-potency dopamine D₂ receptor antagonist
Agren R; Sahlholm K
Article: TOXICS. 2023;11(12):959
Neuropathy with Cerebral Features Induced by Nitrous Oxide Abuse-A Case Report
Lindeman E; Melin S; Paucar M; Agren R
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2023;26(9):599-606
In Vitro Comparison of Ulotaront (SEP-363856) and Ralmitaront (RO6889450): Two TAAR1 Agonist Candidate Antipsychotics
Agren R; Betari N; Saarinen M; Zeberg H; Svenningsson P; Sahlholm K
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(13):10924
An E280K Missense Variant in KCND3/Kv4.3-Case Report and Functional Characterization
Agren R; Geerdink N; Brunner HG; Paucar M; Kamsteeg E-J; Sahlholm K
Article: MOLECULAR BIOLOGY AND EVOLUTION. 2023;40(6):msad130
Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals
Agren R; Patil S; Zhou X; FinnGen; Sahlholm K; Paabo S; Zeberg H
Article: FRONTIERS IN PHARMACOLOGY. 2023;14:1087171
Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2
Burstrom V; agren R; Betari N; Valle-Leon M; Garro-Martinez E; Ciruela F; Sahlholm K
Article: NEUROPSYCHOPHARMACOLOGY. 2022;47(13):2319-2329
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT_1A receptor agonist SEP-383856
Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ; Svenningsson P
Article: BIOSENSORS-BASEL. 2022;12(8):601
Fluorescence-Based Measurements of Membrane-Bound Angiotensin Converting Enzyme 2 Activity Using Xenopus Laevis Oocytes
Fast L; Agren R; Zeberg H
Article: BIOMEDICINES. 2021;10(1):22
Evidence for Two Modes of Binding of the Negative Allosteric Modulator SB269,652 to the Dopamine D₂ Receptor
agren R; Sahlholm K
Article: FASEB JOURNAL. 2021;35(11):e22013
G protein-coupled receptor kinase-2 confers isoform-specific calcium sensitivity to dopamine D₂ receptor desensitization
Agren R; Sahlholm K
Article: CHEMICAL SCIENCE. 2021;12(33):10990-11003
Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome
Stepniewski TM; Mancini A; Agren R; Torrens-Fontanals M; Semache M; Bouvier M; Sahlholm K; Breton B; Selent J
Article: SCIENTIFIC REPORTS. 2021;11(1):13136
Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
Agren R
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:667854
Voxel-Based Morphometry of Cerebellar Lobules in Essential Tremor
Agren R; Awad A; Blomstedt P; Fytagoridis A
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(8):4078
Dopamine D₂ Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue
Agren R; Stepniewski TM; Zeberg H; Selent J; Sahlholm K
Article: NEUROLOGY-GENETICS. 2021;7(1):e546
V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations
Paucar M; Agren R; Li T; Lissmats S; Bergendal A; Weinberg J; Nilsson D; Savichetva I; Sahlholm K; Nilsson J; Svenningsson P
Article: JOURNAL OF NEUROSCIENCE METHODS. 2021;348:108984
Low-Resistance silver bromide electrodes for recording fast ion channel kinetics under voltage clamp conditions
Agren R; Zeberg H
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:581151
Voltage-Dependent Dopamine Potency at D₁-Like Dopamine Receptors
Agren R; Sahlholm K
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(19):3130-3143
Ligand with Two Modes of Interaction with the Dopamine D₂ Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism
Agren R; Zeberg H; Stepniewski TM; Free RB; Reilly SW; Luedtke RR; Arhem P; Ciruela F; Sibley DR; Mach RH; Selent J; Nilsson J; Sahlholm K
Article: STEREOTACTIC AND FUNCTIONAL NEUROSURGERY. 2020;98(5):331-336
Pulse Width and Implantable Pulse Generator Longevity in Pallidal Deep Brain Stimulation for Dystonia: A Population-Based Comparative Effectiveness Study
Agren R; Bartek JJ; Johansson A; Blomstedt P; Fytagoridis A
Article: SCIENTIFIC REPORTS. 2019;9(1):8175
Closed and open state dependent block of potassium channels cause opposing effects on excitability - a computational approach
Agren R; Nilsson J; Arhem P
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2018;21(12):1102-1108
The Beta-Arrestin-Biased Dopamine D₂ Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation
Agren R; Arhem P; Nilsson J; Sahlholm K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;496(1):101-104
Point mutation of a conserved aspartate, D69, in the muscarinic M₂ receptor does not modify voltage-sensitive agonist potency
Agren R; Sahlholm K; Nilsson J; Arhem P
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Review: CURRENT OPINION IN VIROLOGY. 2026;75:101513
Ancestral FUT2 genetic adaptation confers resistance to modern norovirus and rotavirus infections
Nordgren J; Agren R; Hagbom M; Zeberg H; Svensson L

Anställningar

Biträdande Lektor, Fysiologi och farmakologi, Karolinska Institutet, 2024-2030
Postdoktor, Fysiologi och farmakologi, Karolinska Institutet, 2023-2024

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