Pontus Forsell

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: PSYCHOPHARMACOLOGY. 2023;240(8):1789-1804
Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling - a potential therapeutic concept?
Madjid N; Lidell V; Nordvall G; Lindskog M; Ogren S-O; Forsell P; Sandin J
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(13):11159
Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease
Fernandez CP; Juric S; Backlund M; Dahlstrom M; Madjid N; Lidell V; Rasti A; Sandin J; Nordvall G; Forsell P
Article: CELLS. 2021;10(8):1871
Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction
Dahlstrom M; Madjid N; Nordvall G; Halldin MM; Vazquez-Juarez E; Lindskog M; Sandin J; Winblad B; Eriksdotter M; Forsell P
Article: BMC BIOLOGY. 2021;19(1):57
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
Naia L; Pinho CM; Dentoni G; Liu J; Leal NS; Ferreira DMS; Schreiner B; Filadi R; Fao L; Connolly NMC; Forsell P; Nordvall G; Shimozawa M; Greotti E; Basso E; Theurey P; Gioran A; Joselin A; Arsenian-Henriksson M; Nilsson P; Rego AC; Ruas JL; Park D; Bano D; Pizzo P; Prehn JHM; Ankarcrona M
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2019;50(9):3487-3501
Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons
Dahlstrom M; Nordvall G; Sundstrom E; Akesson E; Tegerstedt G; Eriksdotter M; Forsell P
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2015;25(15):3024-3029
3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1
Pelcman B; Sanin A; Nilsson P; No K; Schaal W; Ohrman S; Krog-Jensen C; Forsell P; Hallberg A; Larhed M; Boesen T; Kromann H; Vogensen SB; Groth T; Claesson H-E
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2015;25(15):3017-3023
N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase
Pelcman B; Sanin A; Nilsson P; Schaal W; Olofsson K; Krog-Jensen C; Forsell P; Hallberg A; Larhed M; Boesen T; Kromann H; Claesson H-E
Article: FRONTIERS IN PHARMACOLOGY. 2014;5:102
The battle of Alzheimer's Disease - the beginning of the future Unleashing the potential of academic discoveries
Lundkvist J; Halldin MM; Sandin J; Nordvall G; Forsell P; Svensson S; Jansson L; Johansson G; Winblad B; Ekstrand J
Article: JOURNAL OF BIOMOLECULAR SCREENING. 2013;18(6):659-669
The Use of TrkA-PathHunter Assay in High-Throughput Screening to Identify Compounds That Affect Nerve Growth Factor Signaling
Forsell P; Almqvist H; Hillertz P; Akerud T; Otrocka M; Eisele L; Sun K; Andersson H; Trivedi S; Wollberg AR; Dekker N; Rottici D; Sandberg K
Article: LIPIDS. 2012;47(8):781-791
Metabolism of Anandamide into Eoxamides by 15-Lipoxygenase-1 and Glutathione Transferases
Forsell PKA; Brunnstrom A; Johannesson M; Claesson H-E
Article: EXPERIMENTAL CELL RESEARCH. 2012;318(3):169-176
Epigenetic and transcriptional control of the 15-lipoxygenase-1 gene in a Hodgkin lymphoma cell line
Liu C; Schain F; Han H; Xu D; Andersson-Sand H; Forsell P; Claesson H-E; Bjorkholm M; Sjoberg J
Article: JOURNAL OF BIOMOLECULAR SCREENING. 2010;15(6):671-679
Development of a fluorescent intensity assay amenable for high-throughput screening for determining 15-lipoxygenase activity.
Dahlström M; Forsström D; Johannesson M; Huque-Andersson Y; Björk M; Silfverplatz E; Sanin A; Schaal W; Pelcman B; Forsell PKA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(8):5369-5376
Applicability of the Triad Concept for the Positional Specificity of Mammalian Lipoxygenases
Vogel R; Jansen C; Roffeis J; Reddanna P; Forsell P; Claesson H-E; Kuhn H; Walther M
Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2010;82(2-3):121-129
Cloning, purification and characterization of non-human primate 12/15-lipoxygenases
Johannesson M; Backman L; Claesson H-E; Forsell PKA
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2007;79(6):468-476
The expression of cytosolic phospholipase A₂ and biosynthesis of leukotriene B₄ in acute myeloid leukemia cells
Runarsson G; Feltenmark S; Forsell PKA; Sjoberg J; Bjorkholm M; Claesson H-E
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(42):30423-30433
Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
Ruffolo SC; Forsell PKA; Yuan X; Desmarais S; Himms-Hagen J; Cromlish W; Wong KK; Kennedy BP
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2006;1761(12):1498-1505
Interaction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activity
Andersson E; Schain F; Svedling M; Claesson H-E; Forsell PKA
Article: BIOCHEMICAL PHARMACOLOGY. 2005;71(1-2):144-155
Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A₂-α
Forsell PKA; Olsson AO; Andersson E; Nallan L; Gelb MH
Article: EXPERIMENTAL CELL RESEARCH. 2004;297(1):61-67
Transcriptional regulation of 15-lipoxygenase expression by promoter methylation
Liu C; Xu DW; Sjöberg J; Forsell P; Björkholm M; Claesson HE
Article: FEBS JOURNAL. 1999;262(2):575-585
The human calcium-independent phospholipase A₂ gene -: Multiple enzymes with distinct properties from a single gene
Forsell PKAL; Kennedy BP; Claesson HE
Article: FEBS LETTERS. 1998;434(3):295-299
On the expression of cytosolic calcium-independent phospholipase A₂ (88 kDa) in immature and mature myeloid cells and its role in leukotriene synthesis in human granulocytes
Forsell PKAL; Runarsson G; Ibrahim M; Björkholm M; Claesson HE
Article: BIOCHEMICAL PHARMACOLOGY. 1998;55(6):863-871
Effects of 1-chloro-2,4,6-trinitrobenzene on 5-lipoxygenase activity and cellular leukotriene synthesis
Lasson PKA; Hammarberg T; Johnsson T; Lindgren J; Rådmark O; Claesson HE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(1):207-214
Multiple splice variants of the human calcium-independent phospholipase A₂ and their effect on enzyme activity
Larsson PKA; Claesson HE; Kennedy BP
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(10):2257-2263
Expression of phospholipase A(2) isoforms in human normal and atherosclerotic arterial wall
Elinder LS; Dumitrescu A; Larsson P; Hedin U; Frostegard J; Claesson HE
Article: CELL DEATH AND DIFFERENTIATION. 1997;4(6):479-486
Inhibitors of arachidonic acid metabolism reduce DNA and nuclear fragmentation induced by TNF plus cycloheximide in U937 cells
Vanags DM; Larsson P; Feltenmark S; Jakobsson PJ; Orrenius S; Claesson HE; AguilarSantelises M
Article: FEBS JOURNAL. 1995;232(1):37-46
STUDIES ON THE REGULATION AND LOCALIZATION OF 5-LIPOXYGENASE IN HUMAN B-LYMPHOCYTES
JAKOBSSON PJ; SHASKIN P; LARSSON P; FELTENMARK S; ODLANDER B; AGUILARSANTELISES M; JONDAL M; BIBERFELD P; CLAESSON HE
Article: BRITISH JOURNAL OF HAEMATOLOGY. 1995;90(3):585-594
DIVERSE EXPRESSION OF CYTOSOLIC PHOSPHOLIPASE-A(2), 5-LIPOXYGENASE AND PROSTAGLANDIN-H SYNTHASE-2 IN ACUTE PRE-B-LYMPHOCYTIC LEUKEMIA-CELLS
FELTENMARK S; RUNARSSON G; LARSSON P; JAKOBSSON PJ; BJORKHOLM M; CLAESSON HE
Visa fler

Alla övriga publikationer

Review: DRUG DISCOVERY TODAY. 2022;27(10):103318
Neurotrophin-targeted therapeutics: A gateway to cognition and more?
Nordvall G; Forsell P; Sandin J
Review: DESIGN OF COVALENT-BASED INHIBITORS. 2014;49:59-73
Stimulating Neurotrophin Receptors in the Treatment of Neurodegenerative Disorders
Nordvall G; Forsell P
Corrigendum: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2009;1791(1):84
Interaction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activity (vol 1761, pg 1498, 2006)
Andersson E; Schain F; Svedling M; Claesson H-E; Forsell PKA
Doctoral thesis: 1998
Studies on the structure, function and expression of phospholipase A2
Larsson Forsell, Pontus
Review: ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH. 1995;23:293-298
THE 5-LIPOXYGENASE PATHWAY IN NORMAL AND MALIGNANT HUMAN B-LYMPHOCYTES
JAKOBSSON PJ; LARSSON P; FELTENMARK S; ODLANDER B; RUNARSSON G; BJORKHOLM M; CLAESSON HE

Anställningar

Anknuten till Forskning, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2023-2025

Examina och utbildning

MEDICINE DOKTORSEXAMEN, Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet, 1998

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI