Magnus Ingelman-Sundberg
Om mig
Professor i molekylär toxikologi sedan 1996, sedan 2006 vid sektionen för farmakogenetik på Institutionen för fysiologi och farmakologi.
Tidigare anställningar vid KI omfattar forskarassistent i fysiologisk kemi 1976-1977- lektor i fysiologisk kemi 1977-1987 (formellt anställd 1982)
- och tf professor i fysiologisk kemi 1987-1995. Nu sektionschef vid Institutionen för fysiologi och farmakologi. Leder en forskargrupp om cirka 7-8 personer. Forskningen är inriktad på genetiska faktorer av betydelse för interindividuella skillnader i läkemedelseffekter och biverkningar samt studier i ett nytt 3D system rörande mekanismer för läkemedelsutlösta biverkningar och enzyminduktion i lever samt mekanismer för uppkomst och behandling av leversjukdomar.
Utbildning
Civilingenjör, KungligaTekniska Högskolan, Stockholm, 1975
Tekn Dr i fysiologisk kemi 1975
Docent i fysiologisk kemi 1977
Med kand Karolinska Institutet 1978.
Akademiska priser och utmärkelser
Mer än 490 originalarbeten, 31 024 citeringar (ISI) (45 519 Google Scholar) och en h-faktor på 98 (ISI) eller 128 (Google Scholar). Ledamot av Nobelförsamlingen vid Karolinska Institutet 2008-2018. Medlem i Editorial Advisory Boards i t.ex. Trends Pharmacol Sci, Pharmacogenetics and Genomics, Pharmacogenomics, Drug Metabolism Reviews, Drug Metabolism and Disposition, Human Genomics. Ordförande i International Advisory Board of Microsomes and Drug Oxidations 2004-20229. Rankad som en av världens mest inflytelserika forskare (http://sciencewatch.com/sites/sw/files/sw-article/media/worlds-most-inf…) som bygger på citeringar från högt rankade tidskrifter. HIghly cited from Clarivate 2014-2017 coh 2021. Forskningsgruppen rankad outstanding i Karolinska Institutets externa utvärdering External Research Assessment (ERA) 2010. ERC Advanced grant (AdG) för 2017-2022.
Huvudhandledare till doktorsexamen för 33 doktorander, postdoc-utbildning för 34 doktorer. Priser inkluderar The Svedberg Pris, (Svenska föreningen för biokemi och molekylärbiologi) 1989 - hedersmedlem i American Society for Biochemistry and Molecular Biology 1990
- The Gerhard B Zbinden Föreläsning Award, EUROTOX 1996
- The ISSX European Scientific Achievement Award 2003
- Bengt Danielsson-priset, Swedish Academy of Pharmaceutical Sciences 2008
- The John G Warner Pfizer lecture award in Pharmaceutical Sciences, University of Michigan, USA 2011, 2918 BCPT Nordic Prize in Basic and Clinical Pharmacology and Toxicology. The 2022 R.T. Williams Distinguished Scientific Achievement Award
Övrigt:
Linjenämnden för läkarutbildning : Ordf för studieplanekommitten 3 år, ansvarig för den nya KI 90 GUL studieplan för läkarutbildingen, ledamot 5 år. Docenturnämnden 6 år, ordförande i KIRT 6 år, ordförande för kommittén för valfria perioder i MD läroplan 6 år. Vice ordförande rekryteringsutskottet 3 år, ordförande i rekryteringsutskottet 6 år (till mars 2014) och prodekan (vice dekanus) för rekrytering 2 år. Ordförande i beredningsgrupp vid Naturvetenskapliga forskningsrådet 3 år, medlem i beredningsgrupper vid Naturvetenskapliga forskningsrådet i 6 år, Medicinska forskningsrådet i 6 år, och Norska Forskningsrådet i 6 år.Pedagogiska priser: Mäster 1978, medicinska föreningen - KIs pedagogiska pris 2000. Medlem i Nobelförsamlingen Karolinska Institutet 2008-2018.
Forskningsbeskrivning
Nya in vitro-system har utvecklats som kan förutsäga metabolism och levertoxicitet av läkemedel. Nya genetiska faktorer har identifierats som kan utgöra farmakogenomiska biomarkörer för individualisering av läkemedelsbehandling. Rollen av mutationer för individualiserad läkemedelsterapi undersökes. I leverorganoidsystem med bibehållen leverfenotyp studeras mekanismer och behandling av leversjukdomar såsom steatos, fibros, och hepatit.
Current funding as PI
• Hjärnfonden 2023-2026
• ERC PoC 2023-2025
• Vetenskapsrådet 2022-2024
• Novartis 2024-2026
Undervisning
Har undervisat läkarstudenter sedan 1977 i fysiologisk kemi och basal farmakologi.
Artiklar
- Journal article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2024;80(10):1531-1541
- Journal article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2024;116(4):899-901
- Journal article: JAMA NETWORK OPEN. 2024;7(8):e2425593
- Journal article: EUROPEAN PSYCHIATRY. 2024;67:s44-s45
- Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2024;90(3):740-747
- Article: HEPATOLOGY COMMUNICATIONS. 2024;8(3):e0374
- Article: CLINICAL AND TRANSLATIONAL SCIENCE. 2024;17(2):e13743
- Article: SCIENTIFIC REPORTS. 2024;14(1):1396
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2023;114(3):673-685
- Journal article: THE BIOMEDICAL & LIFE SCIENCES COLLECTION. 2023;2023(6):e1006061
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2023;113(6):1284-1294
- Article: PHARMACOGENOMICS. 2023;24(5):243-246
- Article: THE LANCET. 2023;401(10374):347-356
- Article: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2023;49(1):e12867
- Article: CELLS. 2023;12(2):302
- Journal article: NEUROSCIENCE APPLIED. 2023;2:102913
- Journal article: NEUROSCIENCE APPLIED. 2023;2:102609
- Article: CLINICAL AND TRANSLATIONAL SCIENCE. 2023;16(1):62-72
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2022;112(5):1000-1003
- Article: CLINICAL AND TRANSLATIONAL SCIENCE. 2022;15(9):2135-2145
- Article: PHARMACOGENOMICS JOURNAL. 2022;22(4):247-249
- Article: CELLS. 2022;11(10):1597
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2022;111(5):1165-1174
- Article: CELLS. 2022;11(9):1388
- Journal article: NEUROSCIENCE APPLIED. 2022;1:100236
- Article: ADVANCES IN PHARMACOLOGY. 2022;95:393-416
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2021;110(3):750-758
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2021;110(3):786-793
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(603):eabf3637
- Article: DRUG METABOLISM AND DISPOSITION. 2021;49(7):DMD-AR-2020-000340-508
- Article: SCHIZOPHRENIA RESEARCH. 2021;228:590-596
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2020;108(4):844-855
- Article: PHARMACOGENETICS AND GENOMICS. 2020;30(6):131-144
- Article: ADVANCED SCIENCE. 2020;7(15):2000248
- Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;37:64-69
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2020;107(5):1240-1255
- Article: CELLS. 2020;9(4):E964-964
- Article: NEUROPSYCHOPHARMACOLOGY. 2020;45(3):570-576
- Article: PHARMACOGENOMICS. 2019;20(15):1063-1069
- Article: TOXICOLOGICAL SCIENCES. 2019;171(2):385-395
- Article: PHARMACOGENOMICS. 2019;20(15):1085-1092
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2019;106(4):866-873
- Article: SCIENTIFIC REPORTS. 2019;9(1):11585
- Article: EUROPEAN JOURNAL OF CANCER. 2019;114:128-136
- Article: THE LANCET PSYCHIATRY. 2019;6(5):418-426
- Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2019;130:65-77
- Article: ARCHIVES OF TOXICOLOGY. 2019;93(2):385-399
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(1):217-226
- Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2019;85(1):194-201
- Article: TOXICOLOGY LETTERS. 2018;295:187-194
- Article: SCIENTIFIC REPORTS. 2018;8(1):14297
- Article: PHARMACOGENOMICS. 2018;19(14):1133-1138
- Article: TISSUE ENGINEERING - PART C: METHODS. 2018;24(9):534-545
- Article: PHARMACOGENOMICS. 2018;19(12):931-936
- Article: TOXICOLOGICAL SCIENCES. 2018;163(2):655-665
- Article: GENETICS IN MEDICINE. 2018;20(6):622-629
- Article: HUMAN GENOMICS. 2018;12(1):26
- Article: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(5):463-470
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2018;103(5):745-748
- Article: TOXICOLOGICAL SCIENCES. 2018;162(2):655-666
- Article: APPLIED IN VITRO TOXICOLOGY. 2018;4(1):1-12
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2018;103(3):399-401
- Journal article: PROCEEDINGS FOR ANNUAL MEETING OF THE JAPANESE PHARMACOLOGICAL SOCIETY. 2018;WCP2018(0):po4-9-16
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2017;102(4):688-700
- Journal article: MOLECULAR PSYCHIATRY. 2017;22(8):1224
- Article: MOLECULAR PSYCHIATRY. 2017;22(8):1155-1163
- Journal article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2017;102(1):152
- Article: THE FASEB JOURNAL. 2017;31(6):2696-2708
- Article: DRUG METABOLISM AND DISPOSITION. 2017;45(4):419-429
- Article: ARCHIVES OF TOXICOLOGY. 2017;91(3):1385-1400
- Article: ACTA PHARMACEUTICA SINICA B. 2017;7(2):241-248
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2017;101(3):341-358
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;482(3):399-407
- Article: GENETICS IN MEDICINE. 2017;19(1):20-29
- Article: HEPATOLOGY. 2016;64(5):1743-1756
- Article: SCIENTIFIC REPORTS. 2016;6:35434
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2016;44(14):6756-6769
- Journal article: CANCER RESEARCH. 2016;76(14_Supplement):3105
- Article: PHARMACOGENOMICS. 2016;17(8):917-924
- Article: SCIENTIFIC REPORTS. 2016;6:25187
- Article: FEBS LETTERS. 2016;590(3):330-339
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2016;99(2):172-185
- Article: STEM CELLS INTERNATIONAL. 2016;2016:2475631
- Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2016;856:259-297
- Article: PLOS ONE. 2016;11(9):e0162379
- Article: PHARMACOGENETICS AND GENOMICS. 2015;25(12):584-594
- Article: TOXICOLOGICAL SCIENCES. 2015;147(2):412-424
- Journal article: APPLIED IN VITRO TOXICOLOGY. 2015;1(3):175-186
- Article: PHARMACOGENOMICS JOURNAL. 2015;15(3):288-292
- Article: PHARMACOGENOMICS JOURNAL. 2015;15(3):201-210
- Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 2015;36(2):65-67
- Article: CLINICAL CANCER RESEARCH. 2015;21(2):322-328
- Article: PHARMACOGENOMICS. 2015;16(9):929-937
- Article: PLOS ONE. 2015;10(9):e0138487
- Article: PLOS ONE. 2015;10(4):e0122820
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2015;78:202-212
- Article: BMC GENOMICS. 2014;15(1):860
- Article: DRUG METABOLISM AND DISPOSITION. 2014;42(9):1401-1406
- Article: PHARMACOGENOMICS JOURNAL. 2014;14(4):343-349
- Article: ACTA ONCOLOGICA. 2014;53(7):885-891
- Article: OMICS A JOURNAL OF INTEGRATIVE BIOLOGY. 2014;18(7):446-453
- Article: MOLECULAR PSYCHIATRY. 2014;19(6):733-741
- Article: PHARMACOGENOMICS. 2013;14(13):1615-1622
- Article: DRUG METABOLISM AND DISPOSITION. 2013;41(10):1725-1731
- Article: GENOME BIOLOGY. 2013;14(8):R83
- Article: JOURNAL OF MEDICINAL CHEMISTRY. 2013;56(15):6273-6277
- Article: MOLECULAR PHARMACEUTICS. 2013;10(8):3152-3163
- Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2013;113(2):126-131
- Article: CLINICAL CANCER RESEARCH. 2013;19(11):2952-2961
- Article: TOXICOLOGICAL SCIENCES. 2013;133(1):67-78
- Journal article: DRUG METABOLISM AND DISPOSITION. 2013;41(4):932
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2013;41(6):e72
- Article: JOURNAL OF AFFECTIVE DISORDERS. 2013;146(1):91-99
- Article: DRUG METABOLISM AND DISPOSITION. 2013;41(3):651-658
- Article: MOLECULAR PHARMACOLOGY. 2013;83(3):659-670
- Article: STEM CELLS AND DEVELOPMENT. 2013;22(4):581-594
- Article: METHODS IN MOLECULAR BIOLOGY. 2013;987:251-259
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2012;92(6):727-736
- Article: BIOCHIMIE. 2012;94(11):2338-2344
- Article: ANTICANCER RESEARCH. 2012;32(9):3869-3874
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2012;92(2):221-227
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2012;68(4):407-413
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2012;68(4):397-406
- Article: JOURNAL OF PSYCHOPHARMACOLOGY. 2012;26(3):398-407
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(9):6307-6317
- Article: TOXICOLOGICAL SCIENCES. 2011;124(2):278-290
- Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2011;338(1):302-309
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2011;89(6):902-907
- Article: ATLA ALTERNATIVES TO LABORATORY ANIMALS. 2011;39(2):147-171
- Article: TOXICOLOGICAL SCIENCES. 2011;120(1):1-13
- Article: MOLECULAR PHARMACOLOGY. 2010;78(6):1004-1011
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2010;66(12):1199-1205
- Article: BIOCHEMICAL PHARMACOLOGY. 2010;80(10):1592-1600
- Article: MOLECULAR PHARMACOLOGY. 2010;78(5):886-894
- Article: JOURNAL OF HEPATOLOGY. 2010;53(3):431-438
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2010;66(9):871-877
- Article: AMERICAN JOURNAL OF MEDICAL GENETICS, PART B: NEUROPSYCHIATRIC GENETICS. 2010;153B(6):1160-1166
- Article: HUMAN GENOMICS. 2010;4(6):402-405
- Article: DRUG METABOLISM AND DISPOSITION. 2010;38(6):995-1002
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):90-94
- Article: LIFE SCIENCES. 2010;86(19-20):699-706
- Article: PHARMACOGENOMICS. 2010;11(5):625-627
- Article: HUMAN GENOMICS. 2010;4(4):278-281
- Article: DRUG METABOLISM AND DISPOSITION. 2010;38(3):415-421
- Article: JOURNAL OF BIOTECHNOLOGY. 2010;145(3):284-294
- Article: INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE. 2010;51(1):249-254
- Article: TOXICOLOGY IN VITRO. 2009;23(7):1387-1395
- Article: DRUG METABOLISM AND DISPOSITION. 2009;37(7):1505-1512
- Article: DRUG METABOLISM AND DISPOSITION. 2009;37(7):1528-1538
- Article: PHARMACOGENOMICS JOURNAL. 2009;9(3):208-217
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2009;85(4):426-430
- Journal article: CHEMMEDCHEM. 2009;4(3):473-474
- Article: JOURNAL OF HEPATOLOGY. 2009;50(3):572-583
- Article: EUROPEAN JOURNAL OF CANCER. 2009;45(4):705-712
- Article: EXPERT REVIEW OF CLINICAL PHARMACOLOGY. 2009;2(1):55-65
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(12):1175-1179
- Article: TOXICOLOGY IN VITRO. 2008;22(6):1588-1594
- Article: HUMAN MUTATION. 2008;29(9):1147-1153
- Article: PHARMACOGENOMICS JOURNAL. 2008;8(4):268-277
- Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2008;65(5):767-774
- Article: DRUG METABOLISM AND DISPOSITION. 2008;36(5):955-962
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2008;17(5):1120-1126
- Article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2008;233(3):344-355
- Journal article: DRUG DISCOVERY TODAY: TECHNOLOGIES. 2008;5(4):e143-e147
- Article: CYTOGENETIC AND GENOME RESEARCH. 2008;123(1-4):195-204
- Article: PHARMACOGENOMICS. 2007;8(10):1315-1325
- Journal article: THE BIOMEDICAL & LIFE SCIENCES COLLECTION. 2007;2007(10):e1001124
- Article: REGULATORY PEPTIDES. 2007;142(3):95-100
- Article: BIOCHEMICAL PHARMACOLOGY. 2007;74(3):496-503
- Article: DRUG METABOLISM AND DISPOSITION. 2007;35(6):831-834
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2007;63(6):537-546
- Journal article: JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. 2006;29(s1):2
- Journal article: JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. 2006;29:1-2
- Article: PHARMACOGENETICS AND GENOMICS. 2006;16(5):359-367
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2006;79(4):339-349
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;341(2):451-458
- Article: PHARMACOGENETICS AND GENOMICS. 2006;16(3):191-198
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;340(2):491-497
- Article: METHODS IN MOLECULAR BIOLOGY. 2006;320:183-191
- Article: METHODS IN MOLECULAR BIOLOGY. 2006;320:183-191
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2006;79(1):103-113
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;338(2):1065-1074
- Article: BIOCHEMICAL PHARMACOLOGY. 2005;70(8):1253-1261
- Article: PHARMACOGENETICS AND GENOMICS. 2005;15(9):625-631
- Article: ATHEROSCLEROSIS. 2005;182(1):37-45
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2005;39(5):619-630
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(31):28324-28331
- Article: TOXICOLOGY IN VITRO. 2005;19(5):621-629
- Article: CANCER RESEARCH. 2005;65(12):5105-5111
- Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2005;29(6):1060-1065
- Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2005;313(2):814-822
- Article: DRUG METABOLISM AND DISPOSITION. 2005;33(4):570-578
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2005;77(4):259-270
- Article: JOURNAL OF NEUROCHEMISTRY. 2005;92(4):915-924
- Article: BREAST CANCER RESEARCH. 2005;7(6):R890-R896
- Article: CELLULAR SIGNALLING. 2005;17(1):39-48
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(49):50949-50955
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2004;13(9):1515-1520
- Article: INTERNATIONAL JOURNAL OF CANCER. 2004;110(2):266-270
- Article: PHARMACOGENETICS AND GENOMICS. 2004;14(6):369-379
- Article: BIOCHEMICAL PHARMACOLOGY. 2004;67(7):1389-1397
- Article: BIOCHEMICAL PHARMACOLOGY. 2004;67(7):1249-1258
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;315(3):679-685
- Article: HUMAN MUTATION. 2004;23(3):258-266
- Article: MOLECULAR PHARMACOLOGY. 2004;65(2):416-425
- Article: BIOCHEMISTRY. 2003;42(49):14566-14575
- Article: DRUG METABOLISM AND DISPOSITION. 2003;31(11):1310-1314
- Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2003;59(7):533-536
- Article: CARCINOGENESIS. 2003;24(9):1533-1539
- Article: MOLECULAR PHARMACOLOGY. 2003;64(3):659-669
- Article: DRUG METABOLISM AND DISPOSITION. 2003;31(9):1093-1102
- Article: DRUG METABOLISM AND DISPOSITION. 2003;31(6):755-761
- Article: MOLECULAR PHARMACOLOGY. 2003;63(5):1180-1189
- Article: INTERNATIONAL JOURNAL OF CANCER. 2003;104(5):650-657
- Article: CANCER CAUSES AND CONTROL. 2003;14(4):339-346
- Article: CARCINOGENESIS. 2003;24(4):681-687
- Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2003;304(3):1048-1054
- Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2003;27(2):336-347
- Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2002;408(1):58-68
- Article: JOURNAL OF NEUROCHEMISTRY. 2002;83(3):727-737
- Journal article: DRUG NEWS AND PERSPECTIVES. 2002;15(8):528-534
- Article: HUMAN MUTATION. 2002;20(4):275-283
- Article: CARCINOGENESIS. 2002;23(8):1343-1350
- Article: PHARMACOGENETICS AND GENOMICS. 2002;12(5):375-383
- Article: GASTROENTEROLOGY. 2002;123(1):325-335
- Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2002;127(2):293-302
- Article: MOLECULAR PHARMACOLOGY. 2002;61(3):586-594
- Journal article: CARCINOGENESIS. 2002;23(10):1771
- Journal article: DRUG METABOLISM AND PHARMACOKINETICS. 2002;17(6):491-495
- Article: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2002;71(1):77-88
- Article: PHARMACOGENETICS AND GENOMICS. 2001;11(9):815-824
- Article: PHARMACOGENETICS AND GENOMICS. 2001;11(9):745-746
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2001;10(12):1239-1248
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;288(4):1059-1063
- Article: DRUG METABOLISM AND DISPOSITION. 2001;29(11):1480-1484
- Article: LAKARTIDNINGEN. 2001;98(42):4554-4555
- Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2001;52(4):447-450
- Article: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2001;482(1-2):11-19
- Journal article: INTERNATIONAL CONGRESS SERIES. 2001;1220:175-186
- Article: PHARMACOGENETICS AND GENOMICS. 2001;11(5):417-427
- Article: DRUG METABOLISM AND DISPOSITION. 2001;29(7):1051-1056
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;284(2):455-460
- Article: XENOBIOTICA. 2001;31(6):321-343
- Article: STRUCTURE. 2001;9(6):457-471
- Article: DRUG METABOLISM AND DISPOSITION. 2001;29(5):712-720
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(14):11317-11322
- Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2001;297(1):206-214
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;281(2):529-535
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;279(1):23-29
- Journal article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2000;224(4):302-308
- Article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2000;224(4):302-308
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;274(3):684-688
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(29):21844-21849
- Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2000;20(7):1077-1088
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(22):17130-17135
- Article: JOURNAL OF HEPATOLOGY. 2000;32(6):900-910
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- Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2014;35(8):384-396
- Conference publication: DRUG METABOLISM REVIEWS. 2014;45:210
- Conference publication: DRUG METABOLISM REVIEWS. 2014;45:208
- Editorial comment: PHARMACOGENOMICS. 2014;15(15):1841-1844
- Conference publication: THE FASEB JOURNAL. 2013;27:1102.4
- Review: PHARMACOGENOMICS JOURNAL. 2013;13(1):1-11
- Conference publication: JOURNAL OF NEUROCHEMISTRY. 2013;125:232
- Editorial comment: PHARMACOGENOMICS. 2012;13(16):1887-1891
- Review: PHARMACOGENOMICS. 2012;13(12):1373-1385
- Book chapter: ENCYCLOPEDIA OF LIFE SCIENCES. 2011;p.
- Review: HUMAN MUTATION. 2011;32(5):526-531
- Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2011;32(2):72-81
- Conference publication: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2011;89:S61
- Conference publication: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2011;89:S57
- Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY. 2010;34(6):1075-1084
- Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2010;20:S172-S173
- Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2010;20:S70-S71
- Conference publication: DRUG METABOLISM REVIEWS. 2010;42:82-83
- Conference publication: DRUG METABOLISM REVIEWS. 2010;42:26
- Review: CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT. 2010;13(1):78-85
- Review: HUMAN GENETICS. 2010;127(1):1-17
- Review: PHARMACOGENOMICS. 2009;10(7):1067-1076
- Letter: PHARMACOGENETICS AND GENOMICS. 2009;19(7):565-566
- Review: DRUG DISCOVERY TODAY. 2009;14(7-8):401-405
- Conference publication: DRUG METABOLISM REVIEWS. 2009;41:55
- Conference publication: DRUG METABOLISM REVIEWS. 2009;41:32
- Conference publication: DRUG METABOLISM REVIEWS. 2009;41:12
- Conference publication: DRUG METABOLISM REVIEWS. 2009;41:23
- Conference publication: THE FEBS JOURNAL. 2009;276:25
- Other: DRUG NEWS AND PERSPECTIVES. 2008;21(9):518-528
- Review: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2008;392(6):1075-1084
- Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2008;358(6):637-639
- Conference publication: DRUG METABOLISM REVIEWS. 2008;40:109-110
- Conference publication: DRUG METABOLISM REVIEWS. 2008;40:30
- Conference publication: DRUG METABOLISM REVIEWS. 2008;40:29
- Conference publication: DRUG METABOLISM REVIEWS. 2008;40:98-99
- Review: PHARMACOLOGY AND THERAPEUTICS. 2007;116(3):496-526
- Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2007;13(2):70-71
- Conference publication: GASTROENTEROLOGY. 2007;132(4):A814
- Conference publication: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2007;37:78-79
- Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 2007;61(6):491-492
- Conference publication: DRUG METABOLISM REVIEWS. 2007;39:159-160
- Review: EXPERT OPINION ON THERAPEUTIC TARGETS. 2007;11(1):61-67
- Conference publication: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2007;101(5):361
- Other: DRUG NEWS AND PERSPECTIVES. 2006;19(10):637-651
- Meeting abstract: TOXICOLOGY LETTERS. 2006;164:S7
- Letter: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2006;296(7):764-765
- Review: ONCOGENE. 2006;25(11):1679-1691
- Review: ANNUAL REVIEW OF MEDICINE. 2006;57:119-137
- Review: ATLA ALTERNATIVES TO LABORATORY ANIMALS. 2006;34(1):49-84
- Book chapter: ENCYCLOPEDIA OF LIFE SCIENCES. 2006;p.
- Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:24
- Conference publication: DRUG METABOLISM REVIEWS. 2006;38:57-58
- Conference publication: DRUG METABOLISM REVIEWS. 2006;38:4-5
- Conference publication: AMERICAN JOURNAL OF MEDICAL GENETICS, PART B: NEUROPSYCHIATRIC GENETICS. 2006;141B(7):761-762
- Published conference paper: MUTATION RESEARCH - FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2005;592(1-2):45-57
- Review: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;338(1):299-305
- Review: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2005;207(2 Suppl):52-56
- Review: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2005;207(2 Suppl):57-61
- Published conference paper: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON. BIOLOGICAL SCIENCES. 2005;360(1460):1563-1570
- Review: PHARMACOGENOMICS JOURNAL. 2005;5(1):6-13
- Conference publication: DRUG METABOLISM REVIEWS. 2005;37:51
- Conference publication: DRUG METABOLISM REVIEWS. 2005;37:48-49
- Conference publication: DRUG METABOLISM REVIEWS. 2005;37:27-28
- Conference publication: DRUG METABOLISM REVIEWS. 2005;37:40
- Conference publication: DRUG METABOLISM REVIEWS. 2005;37:75
- Book chapter: ENCYCLOPEDIA OF MEDICAL GENOMICS AND PROTEOMICS. 2004;p. 323-327
- Other: DRUG NEWS AND PERSPECTIVES. 2004;17(9):594-605
- Meeting abstract: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2004;28(8):54A
- Review: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2004;79(6):935-945
- Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2004;25(4):193-200
- Published conference paper: EXPERIMENTAL BIOLOGY AND MEDICINE. 2004;229(4):351-360
- Meeting abstract: JOURNAL OF HEPATOLOGY. 2004;40:163
- Conference publication: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. 2004;31(11):A220
- Conference publication: DRUG METABOLISM REVIEWS. 2004;36:320
- Conference publication: DRUG METABOLISM REVIEWS. 2004;36:101
- Conference publication: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2004;197(3):142
- Conference publication: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2004;197(3):142
- Review: NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY. 2004;369(1):89-104
- Conference publication: THE FASEB JOURNAL. 2004;18(8):C4
- Conference publication: GLIA. 2003;:38
- Conference publication: GLIA. 2003;:37-38
- Conference publication: INTERNATIONAL PSYCHOGERIATRICS. 2003;15:5-6
- Conference publication: DRUG METABOLISM REVIEWS. 2003;35:19
- Published conference paper: TOXICOLOGY. 2002;181:447-452
- Review: BIOMARKERS. 2002;7(3):230-241
- Book chapter: WILEY ENCYCLOPEDIA OF MOLECULAR MEDICINE. 2002;p.
- Conference publication: GLIA. 2002;:S47
- Review: METHODS IN ENZYMOLOGY. 2002;357:28-36
- Conference publication: CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2002;71(2):P41
- Letter: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2001;10(12):1307-1308
- Editorial comment: PHARMACOGENETICS AND GENOMICS. 2001;11(7):553-554
- Review: JOURNAL OF INTERNAL MEDICINE. 2001;250(3):186-200
- Published conference paper: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2001;25(5):237S-243S
- Published conference paper: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2001;25(5):225S-229S
- Published conference paper: ATLA ALTERNATIVES TO LABORATORY ANIMALS. 2001;29(3):305-306
- Conference publication: JOURNAL OF HEPATOLOGY. 2001;34:197
- Published conference paper: DRUG METABOLISM AND DISPOSITION. 2001;29(4):580-585
- Published conference paper: DRUG METABOLISM AND DISPOSITION. 2001;29(4):570-573
- Published conference paper: TOXICOLOGY LETTERS. 2001;120(1-3):259-268
- Published conference paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;281(5):1349-1355
- Corrigendum: PHARMACOGENETICS AND GENOMICS. 2001;11(8):743
- Conference publication: TOXICOLOGY. 2001;164(1-3):152
- Conference publication: TOXICOLOGY. 2001;164(1-3):33
- Published conference paper: CHEMICO-BIOLOGICAL INTERACTIONS. 2001;133(1-3):84-86
- Published conference paper: METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY. 2001;23(6):305
- Letter: PHARMACOGENETICS AND GENOMICS. 2000;10(1):91-93
- Published conference paper: FEBS LETTERS. 1999;460(2):309-314
- Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 1999;20(8):342-349
- Review: FRONTIERS IN BIOSCIENCE - LANDMARK. 1999;4:d533-d540
- Published conference paper: DRUG METABOLISM REVIEWS. 1999;31(2):467-487
- Published conference paper: DRUG METABOLISM REVIEWS. 1999;31(2):449-459
- Published conference paper: TOXICOLOGY LETTERS. 1998;103:155-160
- Published conference paper: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 1998;22(3):740-742
- Published conference paper: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 1998;22(3):739-740
- Published conference paper: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 1998;22(3):738-739
- Conference publication: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 1998;22(3):742
- Published conference paper: HEPATOLOGY. 1998;27(1):128-133
- Corrigendum: FEBS LETTERS. 1998;433(3):335
- Published conference paper: GASTROENTEROLOGY. 1997;113(1):265-276
- Published conference paper: JOURNAL OF NUTRITION. 1997;127(5 Suppl):907S-911S
- Review: ARCHIVES OF TOXICOLOGY. SUPPLEMENT. ARCHIV F�R TOXIKOLOGIE. SUPPLEMENT. 1997;19:3-13
- Conference publication: HEPATOLOGY. 1997;26(4):503
- Conference publication: THE FASEB JOURNAL. 1997;11(9):A1376
- Conference publication: THE FASEB JOURNAL. 1997;11(9):A1374
- Conference publication: THE FASEB JOURNAL. 1997;11(9):A1061
- Conference publication: THE FASEB JOURNAL. 1997;11(9):A827
- Conference publication: THE FASEB JOURNAL. 1997;11(9):A774
- Published conference paper: ENVIRONMENTAL HEALTH PERSPECTIVES. 1996;104(Suppl 6):1183-1188
- Review: PHARMACOGENETICS AND GENOMICS. 1996;6(3):193-201
- Conference publication: HEPATOLOGY. 1996;24(4):1261
- Review: METHODS IN ENZYMOLOGY. 1996;272:218-225
- Conference publication: HEPATOLOGY. 1995;22(4):481
- Review: JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 1995;37(1):25-36
- Conference publication: THE FASEB JOURNAL. 1995;9(6):A1490
- Conference publication: HEPATOLOGY. 1994;20(4):A317
- Book chapter: ASSESSMENT OF THE USE OF SINGLE CYTOCHROME P450 ENZYMES IN DRUG RESEARCH: ERNST SCHERING RESEARCH FOUNDATION WORKSHOP. 1994;p. 195-211
- Conference publication: THE FASEB JOURNAL. 1994;8(5):A806
- Book chapter: MEDICINAL IMPLICATIONS IN CYTOCHROME P-450 CATALYZED BIOTRANSFORMATIONS. 1993;p. 186-232
- Conference publication: HEPATOLOGY. 1993;18(4):A123
- Book chapter: FREE RADICALS: FROM BASIC SCIENCE TO MEDICINE: MOLECULAR AND CELL BIOLOGY UPDATES. 1993;p. 310-322
- Book chapter: FREE RADICALS: FROM BASIC SCIENCE TO MEDICINE: MOLECULAR AND CELL BIOLOGY UPDATES. 1993;p. 287-301
- Conference publication: HEPATOLOGY. 1992;16(2):534
- Conference publication: HEPATOLOGY. 1992;16(4):A232
- Book chapter: ALCOHOLISM: NATO SCIENCE SERIES A:. 1991;p. 45-56
- Conference publication: THE FASEB JOURNAL. 1991;5(6):A1614
- Conference publication: THE FASEB JOURNAL. 1991;5(5):A1451
- Conference publication: THE FASEB JOURNAL. 1991;5(5):A936
- Conference publication: HEPATOLOGY. 1990;12(4):979
- Conference publication: ALCOHOL AND ALCOHOLISM. 1988;23(3):A64
- Conference publication: ALCOHOL AND ALCOHOLISM. 1988;23(3):A64
- Conference publication: ALCOHOL AND ALCOHOLISM. 1988;23(3):A19
- Conference publication: ALCOHOL AND ALCOHOLISM. 1987;22(3):A14
- Conference publication: ALCOHOL AND ALCOHOLISM. 1987;22(3):A15
- Conference publication: ALCOHOL AND ALCOHOLISM. 1987;22(3):A4
- Conference publication: ALCOHOL AND ALCOHOLISM. 1986;21(2):A20
- Book chapter: CYTOCHROME P-450. 1986;p. 119-160
- Book chapter: MICROSOMES, DRUG OXIDATIONS AND CHEMICAL CARCINOGENESIS. 1980;p. 513-516
- Book chapter: MICROSOMES, DRUG OXIDATIONS AND CHEMICAL CARCINOGENESIS. 1980;p. 533-536
- Book chapter: MICROSOMES AND DRUG OXIDATIONS. 1977;p. xv-xxvii
- Book chapter: ABSTRACTS. 1977;p. 65
- Book chapter: MICROSOMES AND DRUG OXIDATIONS. 1977;p. 377-384
- Book chapter: MICROSOMES AND DRUG OXIDATIONS. 1977;p. 67-75
- Conference publication: HOPPE-SEYLER'S ZEITSCHRIFT F�R PHYSIOLOGISCHE CHEMIE. 1976;357(8):1031
- Conference publication: HOPPE-SEYLER'S ZEITSCHRIFT F�R PHYSIOLOGISCHE CHEMIE. 1976;357(8):1022-1023
- Book chapter: PROCEEDINGS OF THE FOURTH INTERNATIONAL CONGRESS ON HORMONAL STEROIDS. 1976;p. 643-649
- Book chapter: RECENT ADVANCES IN STEROID BIOCHEMISTRY. 1975;p. 855-859
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Forskningsbidrag
- Southern and Eastern Norway Regional Health Authority1 January 2022
- Southern and Eastern Norway Regional Health Authority1 January 2020 - 31 December 2023
- A novel regimen for treatment of colon cancer using CYP2W1 as a tumor selective targetNovo Nordisk Foundation1 January 2019 - 31 December 2021
- Swedish Research Council1 December 2018 - 31 December 2023
- Southern and Eastern Norway Regional Health Authority1 January 2018 - 31 December 2022
- CYP2W1 as a prognostic marker and target for pharmacological treatment of colon and liver cancerSwedish Cancer Society1 January 2018
- European Research Council1 September 2017 - 30 June 2023
- VINNOVA1 March 2017 - 28 February 2019
- CYP2W1 as a prognostic marker and target for pharmacological treatment of colon and liver cancerSwedish Cancer Society1 January 2017
- Swedish Research Council1 January 2017 - 31 December 2019
- Swedish Research Council1 January 2016 - 31 December 2019
- New methods of treating colon cancer and other cancers by using CYP2W1 as a target for drug activationSwedish Cancer Society1 January 2016
- Swedish Research Council1 January 2016 - 31 December 2016
- New methods of treating colon cancer and other cancers by using CYP2W1 as a target for drug activationSwedish Cancer Society1 January 2015
- ERA-NET NEURON Mental Disorders RDmaria aDBSSwedish Research Council1 January 2014 - 31 December 2016
- New methods of treating colon cancer and other cancers by using CYP2W1 as a target for drug activationSwedish Cancer Society1 January 2014
- Swedish Research Council1 January 2011 - 31 December 2015
- Swedish Research Council1 January 2009 - 31 December 2011
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning20 November 2008 - 31 December 2008
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Anställningar
- Professor, Senior, Fysiologi och farmakologi, Karolinska Institutet, 2025-2025
- Professor, Fysiologi och farmakologi, Karolinska Institutet, 2020-2024
Examina och utbildning
- Docent, Medicinsk o fysiologisk kemi, Karolinska Institutet, 1977