Elena Kashuba

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: EXPERIMENTAL ONCOLOGY. 2024;45(4):531-534
MATERIALS OF NOBEL SYMPOSIUM 175: PRECISION MEDICINE TRANSFORMS HEALTHCARE: A NEW TRAJECTORY FOR RESEARCH AND INNOVATION SEPTEMBER 20-22, 2023, STOCKHOLM, SWEDEN.
Kovalevska L; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2024;45(4):421-431
EXPRESSION PROFILE OF miR-145, -182, -21, -27a, -29b, and -34a IN BREAST CANCER PATIENTS OF YOUNG AGE.
Chekhun V; Borikun T; Mushii O; Zadvornyi T; Martyniuk О; Kashuba E; Bazas V; Hrybach S; Krotevych M; Lyalkin S; Lukianova N
Article: EXPERIMENTAL ONCOLOGY. 2023;45(3):351-363
FEATURES OF COL1A1 EXPRESSION IN BREAST CANCER TISSUE OF YOUNG PATIENTS.
Chekhun V; Mushii O; Zadvornyi T; Borikun T; Martyniuk О; Kashuba E; Kryzhanivska A; Andriiv A; Diakiv I; Lukianova N
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2023;11:1275668
MTSS1 is downregulated in nasopharyngeal carcinoma (NPC) which disrupts adherens junctions leading to enhanced cell migration and invasion
Zheng S; Wang X; Matskova L; Zhou X; Zhang Z; Kashuba E; Ernberg I; Aspenstrom P
Article: SCIENTIFIC REPORTS. 2022;12(1):22154
STK4 protein expression pattern follows different trends in endometrioid and serous endometrial adenocarcinoma upon tumor progression
Govorov I; Attarha S; Kovalevska L; Andersson E; Kashuba E; Mints M
Article: EXPERIMENTAL ONCOLOGY. 2022;44(1):39-46
EXPRESSION OF MARKERS OF BONE TISSUE REMODELING IN BREAST CANCER AND PROSTATE CANCER CELLS IN VITRO.
Lukianova N; Zadvornyi T; Kashuba E; Borikun T; Mushii О; Chekhun V
Article: EXPERIMENTAL ONCOLOGY. 2022;44(1):47-51
DIFFERENTIAL EXPRESSION PATTERN OF AIP, UCKL1, AND PKN1 GENES IN PROSTATE CANCER PATIENTS.
Kovalevska L; Zadvornyj T; Lukianova N; Kashuba E
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(7):3434
Expression of the Chemokine Receptor CCR1 in Burkitt Lymphoma Cell Lines Is Linked to the CD10-Negative Cell Phenotype and Co-Expression of the EBV Latent Genes EBNA2, LMP1, and LMP2
Zvejniece L; Kozireva S; Rudevica Z; Leonciks A; Ehlin-Henriksson B; Kashuba E; Kholodnyuk I
Article: LIFE. 2022;12(3):376
A Comparative Study on the Viability of Normal and Cancerous Cells upon Irradiation with a Steady Beam of THz Rays
Kovalevska L; Golenkov O; Kulahina Y; Callender T; Sizov F; Kashuba E
Article: ONCOLOGY LETTERS. 2022;23(1):30
Evaluation of dyskerin expression and the Cajal body protein WRAP53β as potential prognostic markers for patients with primary vaginal carcinoma
Ranhem C; Larsson G; Lindqvist D; Sorbe B; Karlsson M; Farnebo M; Hellman K; Kovaleska L; Kashuba E; Andersson S
Article: CANCER CONTROL. 2022;29:10732748221094797
Upregulation of PKN1 as a Prognosis Biomarker for Endometrial Cancer
Govorov I; Attarha S; Kovalevska L; Andersson E; Kashuba E; Mints M
Article: EXPERIMENTAL ONCOLOGY. 2021;43(4):298-305
Differential expression patterns of AIP, UCKL1, and PKN1 genes in breast cancer of different molecular subtypes.
Kovalevska L; Kashuba E; Zadvornyj T; Astrid K; Lukianova N; Chekhun V
Article: EXPERIMENTAL ONCOLOGY. 2021;43(3):204-208
Expression pattern of MRPS18 family genes in gliomas.
Kovalevska LM; Malysheva TA; Kalman SS; Rozumenko AV; Verbova LV; Rozumenko VD; Kashuba EV
Article: EXPERIMENTAL ONCOLOGY. 2020;42(4):295-299
Expression pattern of MRPS18 family genes in malignantly transformed b-cells.
Kovalevska L; Kashuba E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(27):15673-15683
Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2
Mushtaq M; Kovalevska L; Darekar S; Abramsson A; Zetterberg H; Kashuba V; Klein G; Arsenian-Henriksson M; Kashuba E
Article: BRAIN SCIENCES. 2020;10(5):E287-287
Persistent Roseoloviruses Infection in Adult Patients with Epilepsy
Rasa-Dzelzkaleja S; Gravelsina S; Chapenko S; Krukle Z-N; Svirskis S; Suna N; Kashuba E; Karelis G; Murovska M
Article: CELLS. 2019;8(3):E208-208
The Immunogenicity in Mice of HCV Core Delivered as DNA Is Modulated by Its Capacity to Induce Oxidative Stress and Oxidative Stress Response
Jansons J; Sominskaya I; Petrakova N; Starodubova ES; Smirnova OA; Alekseeva E; Bruvere R; Eliseeva O; Skrastina D; Kashuba E; Mihailova M; Kochetkov SN; Ivanov AV; Isaguliants MG
Article: EXPERIMENTAL ONCOLOGY. 2018;40(4):303-308
Overexpression of the mitochondrial ribosomal protein S18-2 in the invasive breast carcinomas.
Buchynska LG; Iurchenko NP; Kashuba EV; Brieieva OV; Glushchenko NM; Mints M; Lukianova NY; Chekhun VF
Article: MEDICINA. 2018;54(5):E67-67
Impact of the Uridine-Cytidine Kinase Like-1 Protein and IL28B rs12979860 and rs8099917 SNPs on the Development of Hepatocellular Carcinoma in Cirrhotic Chronic Hepatitis C Patients-A Pilot Study
Buivydiene A; Liakina V; Kashuba E; Norkuniene J; Jokubauskiene S; Gineikiene E; Valantinas J
Article: VIRUSES. 2018;10(5):E239-239
Upregulation of the Chemokine Receptor CCR2B in EpsteinBarr Virus-Positive Burkitt Lymphoma Cell Lines with the Latency III Program
Kozireva S; Rudevica Z; Baryshev M; Leonciks A; Kashuba E; Kholodnyuk I
Article: SCIENTIFIC REPORTS. 2018;8(1):2268
The MRPS18-2 protein levels correlate with prostate tumor progression and it induces CXCR4-dependent migration of cancer cells
Mushtaq M; Jensen L; Davidsson S; Grygoruk OV; Andren O; Kashuba V; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2017;39(4):286-290
The TGF-beta - SMAD pathway is inactivated in cronic lymphocytic leukemia cells.
Matveeva A; Kovalevska L; Kholodnyuk I; Ivanivskaya T; Kashuba E
Article: VIROLOGY. 2017;512:1-7
Expression of the chemokine receptors CCR1 and CCR2B is up-regulated in peripheral blood B cells upon EBV infection and in established lymphoblastoid cell lines
Kholodnyuk I; Rudevica Z; Leonciks A; Ehlin-Henriksson B; Kashuba E
Article: ONCOTARGET. 2017;8(39):64907-64917
Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells
Mushtaq M; Pangigadde PN; Darekar S; Dissen E; Kashuba E
Article: ACTA NATURAE. 2017;9(3):108-114
Expression Levels of the Uridine-Cytidine Kinase Like-1 Protein As a Novel Prognostic Factor for Hepatitis C Virus-Associated Hepatocellular Carcinomas
Buivydiene A; Liakina V; Valantinas J; Norkuniene J; Mockiene E; Jokubauskiene S; Smaliukiene R; Jancoriene L; Kovalevska L; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2017;39(1):12-16
Do MRPS18-2 and RB proteins cooperate to control cell stemness and differentiation, preventing cancer development?
Kashuba E; Mushtaq M
Article: MICROBIAL ECOLOGY IN HEALTH AND DISEASE. 2017;28(1):1345574
Ancient permafrost staphylococci carry antibiotic resistance genes.
Kashuba E; Dmitriev AA; Kamal SM; Melefors O; Griva G; Römling U; Ernberg I; Kashuba V; Brouchkov A
Article: ONCOTARGET. 2016;7(34):55649-55662
S18 family of mitochondrial ribosomal proteins: evolutionary history and Gly132 polymorphism in colon carcinoma
Mushtaq M; Ali RH; Kashuba V; Klein G; Kashuba E
Article: ONCOTARGET. 2016;7(16):22150-22158
Mitochondrial ribosomal protein S18-2 is highly expressed in endometrial cancers along with free E2F1
Mints M; Mushtaq M; Iurchenko N; Kovalevska L; Stip MC; Budnikova D; Andersson S; Polischuk L; Buchynska L; Kashuba E
Article: ONCOTARGET. 2015;6(25):21016-21028
Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts
Darekar SD; Mushtaq M; Gurrapu S; Kovalevska L; Drummond C; Petruchek M; Tirinato L; Di Fabrizio E; Carbone E; Kashuba E
Article: PLOS ONE. 2015;10(8):e0136142
Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid and Burkitt Lymphoma Cells
Mushtaq M; Darekar S; Klein G; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2014;36(1):34-37
Number of Langerhans cells is decreased in premalignant keratosis and skin cancers.
Shevchuk Z; Filip A; Shevchuk V; Kashuba E
Article: MICROBIOLOGY RESOURCE ANNOUNCEMENTS. 2013;1(4):e00561-e00513
Draft Genome Sequence of Bacillus cereus Strain F, Isolated from Ancient Permafrost.
Brenner EV; Brouchkov AV; Kurilshikov AM; Griva GI; Kashuba E; Kashuba VI; Melefors O; Repin VE; Melnikov VP; Vlassov VV
Article: ACTA NATURAE. 2013;5(1):85-89
Overexpression of MRPS18-2 in Cancer Cell Lines Results in Appearance of Multinucleated Cells
Shevchuk Z; Yurchenko MY; Darekar SD; Holodnuka-Kholodnyuk I; Kashuba VI; Kashuba EV
Article: THE ANALYST. 2012;137(16):3767-3772
Analysis of protein-protein interactions in a complex environment: capture of an analyte-receptor complex with standard additions of the receptor (CARSAR) approach
Snopok BA; Darekar S; Kashuba EV
Article: CELL DEATH AND DISEASE. 2012;3(1):e357
Stem cell gene expression in MRPS18-2-immortalized rat embryonic fibroblasts
Yenamandra SP; Darekar SD; Kashuba V; Matskova L; Klein G; Kashuba E
Article: PLOS ONE. 2012;7(10):e47012
Alterations of the WNT7A Gene in Clear Cell Renal Cell Carcinomas
Kondratov AG; Kvasha SM; Stoliar LA; Romanenko AM; Zgonnyk YM; Gordiyuk VV; Kashuba EV; Rynditch AV; Zabarovsky ER; Kashuba VI
Article: PLOS ONE. 2012;7(7):e42072
Epstein-Barr Virus Immortalization of Human B-Cells Leads to Stabilization of Hypoxia-Induced Factor 1 Alpha, Congruent with the Warburg Effect
Darekar S; Georgiou K; Yurchenko M; Yenamandra SP; Chachami G; Simos G; Klein G; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2011;33(1):9-18
CD150-mediated Akt signalling pathway in normal and malignant B cells.
Yurchenko M; Shlapatska LM; Romanets OL; Ganshevskiy D; Kashuba E; Zamoshnikova A; Ushenin YV; Snopok BA; Sidorenko SP
Article: INTERNATIONAL JOURNAL OF CANCER. 2011;128(4):817-825
Epstein-Barr virus-encoded EBNA-5 forms trimolecular protein complexes with MDM2 and p53 and inhibits the transactivating function of p53
Kashuba E; Yurchenko M; Yenamandra SP; Snopok B; Szekely L; Bercovich B; Ciechanover A; Klein G
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2010;67(24):4249-4256
Epstein-Barr virus encoded EBNA-3 binds to vitamin D receptor and blocks activation of its target genes
Yenamandra SP; Hellman U; Kempkes B; Darekar SD; Petermann S; Sculley T; Klein G; Kashuba E
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):67-73
Interaction of Epstein-Barr virus (EBV) with human B-lymphocytes
Klein G; Klein E; Kashuba E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(47):19866-19871
MRPS18-2 protein immortalizes primary rat embryonic fibroblasts and endows them with stem cell-like properties
Kashuba E; Yenamandra SP; Darekar SD; Yurchenko M; Kashuba V; Klein G; Szekely L
Article: COMPUTERS IN BIOLOGY AND MEDICINE. 2009;39(11):1036-1042
Comparative analysis of the Epstein-Barr virus encoded nuclear proteins of EBNA-3 family
Yenamandra SP; Sompallae R; Klein G; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2009;31(2):92-96
Expression profile of nuclear receptors upon Epstein -- Barr virus induced B cell transformation.
Yenamandra SP; Lundin A; Arulampalam V; Yurchenko M; Pettersson S; Klein G; Kashuba E
Article: MOLECULAR CANCER. 2009;8:23
PRIMA-1^MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein
Stuber G; Flaberg E; Petranyi G; Otvos R; Rokaeus N; Kashuba E; Wiman KG; Klein G; Szekely L
Article: MOLECULAR BIOTECHNOLOGY. 2009;41(3):270-277
Study on the Spatial Architecture of p53, MDM2, and p14ARF Containing Complexes
Savchenko A; Yurchenko M; Snopok B; Kashuba E
Article: EXPERIMENTAL ONCOLOGY. 2008;30(4):327-329
Immunofluorescence staining of paraffin sections: creating DAB staining like virtual digital images using CMYK color conversion.
Buchynska L; Kashuba E; Szekely L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(14):5489-5494
EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes
Kashuba E; Yurchenko M; Yenamandra SP; Snopok B; Isaguliants M; Szekely L; Klein G
Article: EXPERIMENTAL ONCOLOGY. 2007;29(4):287-294
Different trends of p53, MDM2 and p14 ARF expression patterns in endometrial adenocarcinomas versus hyperplasia.
Buchynska LG; Nesina IP; Kashuba EV
Article: ANALYTICAL CHEMISTRY. 2007;79(4):1349-1355
Imaging technique for the screening of protein-protein interactions using scattered light under surface plasmon resonance conditions
Savchenko A; Kashuba E; Kashuba V; Snopok B
Article: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2006;386(7-8):2063-2073
SPR-based immunocapture approach to creating an interfacial sensing architecture: mapping of the MRS18-2 binding site on retinoblastoma protein
Snopok B; Yurchenko M; Szekely L; Klein G; Kashuba E
Article: VACCINE. 2006;24(21):4541-4547
HIV-1 reverse transcriptase targeted for proteasomal degradation as a prototype vaccine against drug-resistant HIV-1
Starodubova E; Boberg A; Kashuba EV; Wahren B; Karpov V; Isaguliants M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(2):1215-1223
Regulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 protein
Kashuba EV; Gradin K; Isaguliants M; Szekely L; Poellinger L; Klein G; Kazlauskas A
Article: CELLULAR ONCOLOGY (DORDRECHT). 2006;28(4):177-190
Hepatitis C virus core protein transforms murine fibroblasts by promoting genomic instability
Smirnova IS; Aksenov ND; Kashuba EV; Payakurel P; Grabovetsky VV; Zaberezhny AD; Vonsky MS; Buchinska L; Biberfeld P; Hinkula J; Isaguliants MG
Article: EXPERIMENTAL CELL RESEARCH. 2005;303(1):47-55
Epstein-Barr virus-encoded EBNA-5 binds to Epstein-Barr virus-induced Fte1/S3a protein
Kashuba E; Yurchenko M; Szirak K; Stahl J; Klein G; Szekely L
Article: VACCINE. 2004;22(13-14):1656-1665
Immunization with hepatitis C virus core gene triggers potent T-cell response, but affects CD4+T-cells
Isaguliants MG; Petrakova NV; Kashuba EV; Suzdaltzeva YG; Belikov SV; Mokhonov VV; Prilipov AG; Matskova L; Smirnova IS; Jolivet-Reynaud C; Nordenfeldt E
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;105(5):644-653
EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells
Kashuba E; Mattsson K; Pokrovskaja K; Kiss C; Protopopova M; Ehlin-Henriksson B; Klein G; Szekely L
Article: MOLECULAR CANCER. 2003;2:18
p14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes.
Kashuba E; Mattsson K; Klein G; Szekely L
Article: BMC CELL BIOLOGY. 2002;3:23
Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase
Kashuba E; Kashuba V; Sandalova T; Klein G; Szekely L
Article: JOURNAL OF GENERAL VIROLOGY. 2002;83(Pt 1):179-188
Latent nuclear antigen of Kaposi's sarcoma herpesvirus/human herpesvirus-8 induces and relocates RING3 to nuclear heterochromatin regions
Mattsson K; Kiss C; Platt GM; Simpson GR; Kashuba E; Klein G; Schulz TF; Szekely L
Article: JOURNAL OF GENERAL VIROLOGY. 2001;82(Pt 2):345-358
Proteasome inhibitor induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5
Pokrovskaja K; Mattsson K; Kashuba E; Klein G; Szekely L
Article: ONCOGENE. 2000;19(14):1801-1806
Epstein-Barr virus encoded nuclear protein EBNA-3 binds XAP-2, a protein associated with Hepatitis B virus X antigen
Kashuba E; Kashuba V; Pokrovskaja K; Klein G; Szekely L
Article: JOURNAL OF GENERAL VIROLOGY. 1999;80:2889-2900
Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin-associated nuclear bodies
Szekely L; Kiss C; Mattsson K; Kashuba E; Pokrovskaja K; Juhasz A; Holmvall P; Klein G
Article: JOURNAL OF GENERAL VIROLOGY. 1999;80:987-995
Epstein-Barr virus infection and mitogen stimulation of normal B cells induces wild-type p53 without subsequent growth arrest or apoptosis
Pokrovskaja K; Okan I; Kashuba E; Löwbeer M; Klein G; Szekely L
Article: JOURNAL OF HUMAN VIROLOGY. 1999;2(1):33-37
Epstein-Barr virus-encoded nuclear protein EBNA-3 interacts with the ε-subunit of the T-complex protein 1 chaperonin complex
Kashuba E; Pokrovskaja K; Klein G; Szekely L
Article: JOURNAL OF GENERAL VIROLOGY. 1997;78:893-903
Role of p53 mutation in polyomavirus-induced tumorigenesis
Wang Q; Kashuba E; Magnusson KP; Pokrovskaja K; Okan I; Klein G; Wiman KG
Article: EUROPEAN JOURNAL OF CANCER PART B: ORAL ONCOLOGY. 1995;31B(5):328-332
Infrequent MDM2 gene amplification and absence of gross WAF1 gene alterations in nasopharyngeal carcinoma
Qian W; Hu LF; Chen F; Wang YS; Magnusson KP; Kashuba E; Klein G; Wiman KG
Article: NUCLEIC ACIDS RESEARCH (NAR). 1995;23(3):362-369
P53 BINDS SINGLE-STRANDED-DNA ENDS THROUGH THE C-TERMINAL DOMAIN AND INTERNAL DNA SEGMENTS VIA THE MIDDLE DOMAIN
BAKALKIN G; SELIVANOVA G; YAKOVLEVA T; KISELEVA E; KASHUBA E; MAGNUSSON KP; SZEKELY L; KLEIN G; TERENIUS L; WIMAN KG
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Review: DISCOVERY MEDICINE. 2023;35(178):733-749
Comparative Analysis of the Embryonal Brain Tumors Based on Their Molecular Features
Shcherbina V; Kovalevska L; Pedachenko E; Malysheva T; Kashuba E
Review: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2016;2016:6468342
DNA Tumor Viruses and Cell Metabolism
Mushtaq M; Darekar S; Kashuba E
Review: ADVANCES IN CANCER RESEARCH. 2016;131:133-157
Role of the RB-Interacting Proteins in Stem Cell Biology
Mushtaq M; Gaza HV; Kashuba EV
Review: EXPERIMENTAL ONCOLOGY. 2009;31(2):67-73
Nuclear receptors and their role in Epstein -- Barr virus induced B cell transformation.
Yenamandra SP; Klein G; Kashuba E
Review: EXPERIMENTAL ONCOLOGY. 2005;27(1):24-30
The role of CD150-SH2D1A association in CD150 signaling in Hodgkin's lymphoma cell lines
Yurchenko MY; Kashuba EV; Shlapatska LM; Sivkovich SA; Sidorenko SP
Thesis / dissertation: 2002
Identification of EBNA binding cellular proteins, using yeast two-hybrid system
Kashuba, Elena
Published conference paper: STUDIES IN SURFACE SCIENCE AND CATALYSIS. 1997;110:1175-1182
Photoimmobilized catalysts for low-temperature oxidation of olefins
Lyashenko LV; Belousov VM; Kashuba EV

Anställningar

Forskare, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2013-2025

Examina och utbildning

Docent, Tumörbiologi, Karolinska Institutet, 2009
MEDICINE DOKTORSEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2003

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