David Moulaee Conradsson

David Moulaee Conradsson

Lektor | Docent
Telefon: +46852486614
Besöksadress: Alfred Nobels allé 23, 14183 Huddinge
Postadress: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Fysioterapi Moulaee-Conradsson, 171 77 Stockholm
Del av:

Om mig

  • Jag är sjukgymnast sedan 2008, lektor och docent vid sektionen för fysioterapi, Karolinska Institutet. Jag tog min kandidatexamen i sjukgymnastik vid Karolinska Institutet, magisterexamen i medicinsk vetenskap vid Karolinska Institutet (2012) och doktorsexamen i medicinska vetenskap vid Karolinska Institutet (2016); Balance control in older adults with Parkinson’s disease: effects of medication and exercise. Efter min doktorandutbildning genomförde jag en post-doc vid Human brain Control of Locomotion Lab, McGill University, Montreal, Kanada under handledning av Associate professor Caroline Paquette.

    Mitt intresse och expertis är inom neurologisk rehabilitering och kliniska och experimentella studier om gångförmåga, motorisk funktion och fysisk aktivitet. Jag har en klinisk position som sjukgymnast på Karolinska Universitetssjukhuset och arbetar som manager för uMOVE core facility på Karolinska Institutet.

    Jag är forskargruppsledare för REACH – digital behandling och prevention. 

Forskningsbeskrivning

  • Min forskning fokuserar på nya behandlingsstrategier för personer som drabbats av neurologisk sjukdomar/skada. Jag har ett särskilt intresse för hälsobefrämjande strategier för sekundärprevention för personer med neurologiska sjukdomar eller skador (stroke, transitorisk ischemisk attack (TIA), Parkinsons sjukdom, ryggmärgsskada).

    Mitt forskningsprogram är primärt inriktat mot att skapa förutsättningar för fysisk aktivitet för personer som drabbats av stroke eller TIA. Övergripande mål är att:

    • Metodutveckla rörelsemätare (accelerometrar) för mätning av fysisk aktivitet vid stroke.
    • Förstå hur personer som haft stroke eller TIA är fysisk aktiva (eller inaktiva) och identifiera faktorer som främjar och begränsar deras engagemang i fysisk aktivitet.
    • Uvecklar och utvärdera digitala interventioner (tex via mobilapplikationer) för att främja fysisk träning och fysisk aktivitet vid stroke/TIA.

      Jag är också intresserad av global hälsa och hur förutsättningarna för rehabilitering och dess utfall skiljer sig mellan olika kontexter. Jag samarbetar till exempel med Associate professor Conran Joseph vid Stellenbosch University och Professor Anthea Rhoda vid University of Western Cape i Kapstaden, Sydafrika inom projektet “Health systems for stroke and spinal cord injury in Sweden and South Africa – a public health perspective on research and education”. Det övergripande målet med projektet är att beskriva och jämföra vårdprocesser och långsiktiga resultat av rehabilitering efter stroke och ryggmärgsskada i Sydafrika och Sverige.

Undervisning

  • Jag har ett stort intresse för det pedagogiska uppdraget och jag undervisar och handleder på grund, avancerad och forskarutbildningsnivå. Min specialisering i undervisning är främst inom digital fysioterapi, mätmetoder av fysisk aktivitet och interventioner för att främja fysisk aktivitet för patientgrupper med neurologiska sjukdomar eller skador.

    Jag är kursledare för kursen “Rehabilitering på distans - ett fysioterapeutiskt perspektiv” (avancerad nivå, 7, 5 hp) som syftar till att förbättra beredskapen hos fysioterapeuter att arbeta på distans med stöd av digitala hjälpmedel. Jag har erfarenhet från samordning och utveckling av kurser, föreläsningar och praktiska seminarier, samt examinator och moderator.

    Jag är även intresserad av internationalisering av utbildning för att förbättra utbildningens kvalitet och mångfald. Inom vårt pågående samarbete med Stellenbosch University och University of Western Cape i Kapstaden arbetar vi till exempel med att definiera universella lärandemål och utforma läraraktiviteter kopplade till studenternas kulturella kompetens.

Utvalda publikationer

Artiklar

Alla övriga publikationer

Utvalda forskningsbidrag

  • Swedish Research Council
    1 januari 2024 - 31 december 2024
  • Swedish Research Council
    1 januari 2023 - 31 december 2026
    The overarching purpose is to improve secondary stroke prevention post stroke or transient ischemic attack (TIA) by increasing access to physical activity through telerehabilitation. This will be accomplished by building on a national collaboration within secondary stroke prevention and by testing a new telerehabilitation program (ENAbLE) developed in Australia.The ENAbLE program seeks to strengthen physical functioning and self-efficacy for exercise through home-based physical exercise and to equip the person with knowledge and confidence to sustain physical activity through behavior change techniques. The program will be accessible via a recent developed mobile application which will be used to reinforce autonomy and patient-therapist partnership.We will first evaluate if a digital version of the ENAbLE program could be delivered as intended through a pilot randomized controlled trial to determine the feasibility, end-users experiences and preliminary effects in people post stroke/TIA living in urban and rural regions of Sweden. We will thereafter perform a full-scale randomized controlled trial to assess the effectiveness of the ENAbLE program on cardiovascular health, physical activity, function, well-being and its cost-effectiveness across Sweden.This project will address the unmet need of providing accessible and sustainable support for physical activity to people post stroke or TIA to decrease the risk of stroke recurrence through adherence to physical activity.
  • Swedish Research Council for Health Working Life and Welfare
    1 januari 2022 - 31 december 2026
    Support for physical activity is necessary to sustain health after stroke and transient ischemic attack (TIA). Still, rehabilitation services are not available to many of those who potentially would benefit due to barriers related to accessibility. While telerehabilitation is a promising strategy to support physical activity, there is a gap of knowledge regarding the implementation of technology that meet the needs of people post stroke or TIA in order to foster adherence and engagement in physical activity.Purpose is to improve health and wellbeing after stroke or TIA by increasing the access to physical activity through telerehabilitation. This will be accomplished by building on a national collaboration within secondary stroke prevention and through testing of an existing telerehabilitation program (ENAbLE) developed in Australia.The ENAbLE program seeks to strengthen physical functioning and self-efficacy for exercise through home-based physical exercise and to equip the person with knowledge and confidence to sustain physical activity through behavior change techniques. The program will be accessible via a recent developed mobile application which will be used to reinforce autonomy and patient-therapist partnership.We will first evaluate if the ENAbLE program can be delivered as intended through a pilot RCT to determine the feasibility, processes, end-users experiences and preliminary effects of the program in urban and rural regions of Sweden. We will thereafter initiate a full-scale RCT to investigate the effects of the ENAbLE program on risk factors for recurrent stroke, well-being and its cost-effectiveness across Sweden.The project will draw on socio-technical theory, depicting technologies as part of a dynamic system in order to explore its potential use in rehabilitation. The ENAbLE program offers a sustainable strategy to support exercise and physical activity which could benefit a large group of people with stroke and TIA regardless of where they live.

Forskningsbidrag

  • Swedish Heart-Lung Foundation
    1 januari 2026 - 31 december 2028
    Background: The prevalence of stroke-related disability is expected to rise globally, significantly impacting families, healthcare systems, and economies. Although strong evidence supports the role of physical activity (PA) in improving health and preventing complications after stroke or transient ischemic attack (TIA), access to support for PA remains limited. When available, such support is often short-term and lacks the long-term personalization needed to sustain behavior change. Objective: This project investigates whether a personalized digital intervention (REACH) can enhance PA and health while reducing secondary complications in individuals post stroke or TIA. The specific objectives are to determine whether the REACH intervention: - Improves PA, physical functioning, well-being, and quality of life immediately after the intervention. - Reduces post-stroke complications and healthcare utilization for up to 5 years post-baseline. - Is cost-effective compared to standard care. We hypothesize that the REACH intervention will improve PA, functioning, well-being, and quality of life
    reduce the incidence of recurrent stroke, comorbidities, mortality, and healthcare utilization
    and be cost-effective, supporting large-scale implementation. Work Plan: In a multicenter Sequential Multiple Assignment Randomized Trial, 371 individuals post-stroke/TIA no longer receiving rehabilitation and with low PA will be randomized to one of two groups: - REACH, a 12-month mHealth intervention incorporating adaptive, personalized treatment trajectories, with physiotherapist-led support for exercise and self-management of PA. - Standard care, without active intervention. Recruitment and trial implementation will be conducted through an established clinical network across 5 Swedish regions. The primary outcome is steps per day, assessed via accelerometry immediately post-intervention. Stroke recurrence, comorbidity, mortality, and healthcare utilization will be tracked for up to 5 years using registry data. Cost-effectiveness will be evaluated through both within-trial and model-based economic analyses. Significance: If REACH improves PA and reduces the risk of secondary complications, it would represent a breakthrough in secondary stroke prevention, offering profound benefits for individuals, healthcare systems, and society. The cost-effectiveness analysis, combined with a scalable digital intervention model, will support national implementation.
  • Vetenskapsrådet
    1 januari 2025 - 31 december 2026
  • Swedish Research Council
    1 januari 2023 - 31 december 2026
    Life means combining motor-cognitive skills, e.g., walking, talking and navigating. Aging or neurological diseases, e.g., Parkinson’s disease (PD) compromises these skills needed for an independent life. It is uncertain which brain alterations lead to these difficulties and how to target these heterogenous motor-cognitive difficulties. Current treatments apply a "one-size-fits-all" approach, which needs to evolve towards personalized rehabilitation, reaching beyond a simple adaption to disease severity.Our multimodal project combines physiotherapy, neurology, psychology and neuroimaging to characterize motor-cognitive skills during complex walking, identify underlying brain alterations and subtype PD to inform a novel exercise approach for people with PD. This 5 years proposal has 4 stages: 1) Exploring brain alterations and links to the motor-cognitive skills in healthy and PD 2) PD subtyping using neuroimaging, motor, cognitive and clinical data 3) Characterization of exercise responsiveness in PD and 4) Development and testing of a personalized motor-cognitive exercise program. We combine novel techniques for data collection with in-depth analysis of existing data (EXPANd trial). The results will have an immediate application and clinical relevance for personalized rehabilitation in older and PD. There is no cure for PD yet, thus positive findings would revolutionize treatment, giving new hope to patients for a life with improved health, independence and higher quality.
  • VINNOVA
    14 juni 2021 - 30 april 2023
  • Fonds de Recherche du Québec - Santé
    1 april 2018 - 31 mars 2019
  • Canadian Institutes of Health Research
    1 april 2017 - 31 mars 2018
  • Fonds de Recherche du Québec - Santé
    1 april 2016 - 31 mars 2018

Anställningar

  • Lektor, Fysioterapi, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2024-
  • Biträdande Lektor, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2019-2024
  • Universitetsadjunkt, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2016-2024

Examina och utbildning

  • Docent, Fysioterapi, Karolinska Institutet, 2021
  • Medicine Doktorsexamen, Institutionen för neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2016
  • Medicine Magisterexamen, Karolinska Institutet, 2014
  • Sjukgymnastexamen, Karolinska Institutet, 2008

Handledning

  • Handledning till doktorsexamen

    • Lisa Sandberg, Physical activity in people with Parkinson’s disease –risk factors, exercise effects and connections to brain function, 2023-
    • Alexander Kvist, Evaluating complex walking in aging and neurological disease: from motor behavior to brain activity, 2021-

Nyheter från KI

Kalenderhändelser från KI