David Moulaee Conradsson
Jag forskar om digital hälso- och sjukvård och rehabilitering, med fokus på att utveckla och utvärdera digitala interventioner för en mer jämlik hälsa.
Om mig
Jag är legitimerad sjukgymnast och universitetslektor (docent) vid Fysioterapi, Karolinska Institutet. Min forskning fokuserar på rehabilitering och hälsofrämjande insatser, med särskilt intresse för fysisk aktivitet och sekundärprevention för personer som lever med neurologiska sjukdomar. Jag bedriver experimentell och interventionell forskning med målet att förbättra hälsa, fysisk funktion och delaktighet i vardagen, med särskilt fokus på digital hälsa och digitalt stöd i vården.
Jag har en bakgrund inom klinisk fysioterapi samt forskning inom rehabilitering och hälsofrämjande arbete. Jag disputerade vid Karolinska Institutet 2016, där jag studerade balanskontroll hos personer med Parkinsons sjukdom, och genomförde därefter postdoktoral forskning vid McGill University i Kanada.
Jag leder idag forskargruppen REACH – Digital Treatment and Prevention, som utvecklar och utvärderar digitala metoder för rehabilitering, fysisk aktivitet och prevention i samverkan mellan forskare, klinisk verksamhet och personer med egen erfarenhet av sjukdom.
Jag är även manager för uMOVE core facility vid Karolinska Institutet, som stödjer forskning inom rörelse och fysisk aktivitet, samt ordförande för Network for Movement and Physical Function.
Forskningsbeskrivning
Min forskning fokuserar på rehabilitering, hälsofrämjande insatser och digital sekundärprevention för olika patientgrupper och i olika faser av återhämtning. Ett centralt tema är hur individanpassade interventioner och digitala hälsolösningar kan stödja fysisk aktivitet, egenvård och långsiktig hälsa. Jag arbetar med flera olika patientgrupper, bland annat personer som återhämtar sig efter stroke och transitorisk ischemisk attack (TIA), personer som lever med Parkinsons sjukdom eller ryggmärgsskada samt barn som återhämtar sig efter cancerbehandling.
Ett särskilt fokus är utveckling och utvärdering av digitala metoder för rehabilitering och sekundärprevention. Detta inkluderar samskapande av tillgängliga och individanpassade digitala interventioner tillsammans med patienter, närstående och hälso- och sjukvårdspersonal samt utvärdering av genomförbarhet, effekt, implementering och långsiktiga konsekvenser i klinisk verksamhet. Min forskning omfattar experimentella och interventionella studier samt användning av patientrapporterade utfallsmått, mätning av fysisk aktivitet och registerbaserad forskning.
Jag medverkar även i internationell forskning inom global hälsa med fokus på rehabilitering och hälsoutfall i olika hälso- och sjukvårdssystem. Tillsammans med professor Conran Joseph (Stellenbosch University) bedriver jag forskning som jämför rehabilitering och hälso- och sjukvårdssystem för personer med stroke och ryggmärgsskada i Sverige och Sydafrika, med målet att bidra till förbättrade och mer jämlika rehabiliteringsinsatser.
Undervisning
Jag har ett stort intresse för utbildning och är aktiv inom undervisning, handledning och kursutveckling på grund-, avancerad- och forskarnivå. Min undervisningserfarenhet omfattar digital fysioterapi, bedömning av fysisk aktivitet samt interventioner för att främja fysisk aktivitet hos personer med neurologiska sjukdomar eller skador.
Jag är kursansvarig för kursen Rehabilitering på distans – ett fysioterapeutiskt perspektiv (7, 5 hp), som jag har utvecklat för att stärka fysioterapeuters kunskap, färdigheter och beredskap att bedriva personcentrerad vård och rehabilitering på distans med stöd av digital teknik. Mer generellt fokuserar mitt pedagogiska arbete på att ge hälso- och sjukvårdspersonal förutsättningar att integrera digitala arbetssätt i klinisk verksamhet, inklusive bedömning, behandling, kommunikation och uppföljning.
Jag undervisar även i kliniska och objektiva metoder för bedömning av rörelse och fysisk aktivitet och bidrar till kursansvar, kursutveckling, föreläsningar, seminarier, examination och internationalisering av utbildning.
Utvalda publikationer
- Article: INTERNATIONAL JOURNAL OF STROKE. 2025;20(7):801-811Thurston C; Humphries S; Bezuidenhout L; Johansson S; Holmlund L; von Koch L; English C; Conradsson DM
- Article: FRONTIERS IN NEUROLOGY. 2024;15:1463162Bezuidenhout L; Humphries S; Moulaee Conradsson D
- Article: PLOS DIGITAL HEALTH. 2024;3(7):e0000563Humphries S; Bezuidenhout L; Haeger CK; Conradsson DM
- Article: INTERNATIONAL JOURNAL OF STROKE. 2023;18(9):1132-1142Fini NA; Simpson D; Moore SA; Mahendran N; Eng JJ; Borschmann K; Conradsson DM; Chastin S; Churilov L; English C
Artiklar
- Article: JMIR CARDIO. 2026;10:e87493Lagerlund H; Conradsson DM; Hager CK; Kwak L; Holmlund L
- Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2026;28:e84163Manser P; Hardeman LES; Wallin A; Conradsson DM; Leavy B; Albrecht F; Roerdink M; Temprado J-J; de Bruin ED; Franzen E
- Article: JMIR MHEALTH AND UHEALTH. 2026;14:e75662Lagerlund H; Bezuidenhout L; Humphries S; Holmlund L; Kwak L; Hager CK; Conradsson DM
- Article: JOURNAL OF NEUROENGINEERING AND REHABILITATION. 2026;23(1):41Kvist A; Peterson DS; Bezuidenhout L; Johansson H; Albrecht F; Ekman U; Conradsson DM; Franzen E
- Journal article: BMC DIGITAL HEALTH. 2026;4(1):1Conradsson DM; Bezuidenhout L; Lagerlund H; Johansson S
- Journal article: DIGITAL HEALTH. 2026;12:20552076261434065Rhoda A; Malema M; Mlenzana N; Bezuidenhout L; Conradsson D; Joseph C; Olotu O; Frantz J
- Article: JOURNAL OF REHABILITATION MEDICINE. 2025;57:jrm43967Tornberg A; Svensson-Raskh A; Bezuidenhout L; Conradsson DM; Svensson A; Bruchfeld J; Rydwik E; Nygren-Bonnier M
- Article: GEOSPATIAL HEALTH. 2025;20(2)Bezuidenhout L; Miller W; Joseph C; Conradsson DM
- Journal article: BMC DIGITAL HEALTH. 2025;3(1):28Thurston C; Johansson S; von Koch L; English C; Conradsson DM
- Article: DIGITAL HEALTH. 2025;11:20552076251387052Humphries S; Conradsson DM
- Article: DISABILITY AND REHABILITATION. 2025;47(9):2436-2442Hedberg-Graff J; Bezuidenhout L; Krumlinde-Sundholm L; Hallgren J; Conradsson DM; Hagstromer M
- Article: PLOS ONE. 2025;20(5):e0307625Conradsson DM; Aktar B; Bezuidenhout L
- Article: DIGITAL HEALTH. 2025;11:20552076251374247Bezuidenhout L; Humphries S; English C; Sundberg CJ; Nilsson M; Conradsson DM
- Article: SCIENTIFIC REPORTS. 2024;14(1):20017Svensson A; Svensson-Raskh A; Holmstrom L; Hallberg C; Bezuidenhout L; Conradsson DM; Stahlberg M; Bruchfeld J; Fedorowski A; Nygren-Bonnier M
- Article: JOURNAL OF NEUROLOGIC PHYSICAL THERAPY. 2024;48(2):75-82Conradsson DM; Leavy B; Hagstromer M; Franzen E
- Article: JOURNAL OF BIOMECHANICS. 2024;162:111907Kvist A; Tinmark F; Bezuidenhout L; Reimeringer M; Conradsson DM; Franzen E
- Article: NEUROIMAGE-CLINICAL. 2024;43:103637Kvist A; Bezuidenhout L; Johansson H; Albrecht F; Conradsson DM; Franzen E
- Article: DISABILITY AND REHABILITATION. 2023;45(26):4381-4387Bezuidenhout L; Rhoda A; Moulaee Conradsson D; Theron F; Joseph C
- Article: SAMJ SOUTH AFRICAN MEDICAL JOURNAL. 2023;113(5):46-53Joseph C; Thurston C; Nizeyimana E; Scriba E; Conradsson DM; Rhoda A
- Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2023;20(9):5709Bezuidenhout L; Rhoda A; Moulaee Conradsson D; Mothabeng J; Joseph C
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Alla övriga publikationer
- Preprint: MEDRXIV. 2025Manser P; Hardeman LES; Wallin A; Conradsson DM; Leavy B; Albrecht F; Roerdink M; Temprado J-J; de Bruin E; Franzen E
- Preprint: RESEARCH SQUARE. 2025Conradsson DM; Bezuidenhout L; Lagerlund H; Johansson S
- Conference publication: INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE. 2025;32(SUPPL1):176Lagerlund H; Conradsson DM; Kwak L; Hager C; Holmlund L
- Preprint: JMIR PREPRINTS. 2025Lagerlund H; Bezuidenhout L; Humphries S; Holmlund L; Kwak L; Häger CK; Moulaee Conradsson D
- Preprint: RESEARCH SQUARE. 2025Thurston C; Johansson S; Koch L; English C; Conradsson DM
- Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2024;19(2):147Thurston C; Lagerlund H; Humphries S; Bezuidenhout L; Johansson S; Conradsson DM
- Study protocol: BMJ OPEN. 2023;13(5):e069747Westergren J; Sjoberg V; Vixner L; Nyberg RG; Moulaee Conradsson D; Monnier A; LoMartire R; Enthoven P; Ang BO
- Study protocol: BMC NEUROLOGY. 2023;23(1):124Thurston C; Bezuidenhout L; Humphries S; Johansson S; von Koch L; Hager CK; Holmlund L; Sundberg CJ; Garcia-Ptacek S; Kwak L; Nilsson M; English C; Conradsson DM
- Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2023;18(1):80Thurston C; Johansson S; Conradsson D
- Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2023;18(1):86-87Moore S; Fini N; Simpson D; Mahendran N; Eng J; Borschmann K; Conradsson DM; Chastin S; Churilov L; English C
- Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2022;17(2_SUPPL):5Fini N; Simpson D; Moore S; Mahendran N; Eng J; Borschmann K; Conradsson DM; Chastin S; Churilov L; English C
- Book chapter: SELF-MANAGEMENT IN CHRONIC ILLNESS. 2021;p. 35-47Nizeyimana E; Conradsson DM; Joseph C
- Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2018;13:8-9Conradsson D; Mitchell T; Thiel A; Paquette C
- Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2016;11(SUPP 3):89Lawal I; Joseph C; Conradsson D; Rhoda A
- Doctoral thesis: 2015Moulaee Conradsson D
- Conference publication: MOVEMENT DISORDERS. 2014;29:S239Franzen E; Conradsson D; Lofgren N; Nero H; Stahle A; Hagstromer M
- Conference publication: MOVEMENT DISORDERS. 2014;29:S232-S233Conradsson D; Paquette C; Franzen E
- Conference publication: MOVEMENT DISORDERS. 2014;29:S186Lofgren N; Lenholm E; Conradsson D; Stahle A; Franzen E
- Conference publication: MOVEMENT DISORDERS. 2014;29:S183Wallen MB; Lofgren N; Conradsson D; Hagstromer M; Franzen E
- Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2012;19:571Conradsson D; Lofgren N; Hagstromer M; Stahle A; Franzen E
Utvalda forskningsbidrag
- Swedish Research Council1 januari 2024 - 31 december 2024
- Swedish Research Council1 januari 2023 - 31 december 2026The overarching purpose is to improve secondary stroke prevention post stroke or transient ischemic attack (TIA) by increasing access to physical activity through telerehabilitation. This will be accomplished by building on a national collaboration within secondary stroke prevention and by testing a new telerehabilitation program (ENAbLE) developed in Australia.The ENAbLE program seeks to strengthen physical functioning and self-efficacy for exercise through home-based physical exercise and to equip the person with knowledge and confidence to sustain physical activity through behavior change techniques. The program will be accessible via a recent developed mobile application which will be used to reinforce autonomy and patient-therapist partnership.We will first evaluate if a digital version of the ENAbLE program could be delivered as intended through a pilot randomized controlled trial to determine the feasibility, end-users experiences and preliminary effects in people post stroke/TIA living in urban and rural regions of Sweden. We will thereafter perform a full-scale randomized controlled trial to assess the effectiveness of the ENAbLE program on cardiovascular health, physical activity, function, well-being and its cost-effectiveness across Sweden.This project will address the unmet need of providing accessible and sustainable support for physical activity to people post stroke or TIA to decrease the risk of stroke recurrence through adherence to physical activity.
- Swedish Research Council for Health Working Life and Welfare1 januari 2022 - 31 december 2026Support for physical activity is necessary to sustain health after stroke and transient ischemic attack (TIA). Still, rehabilitation services are not available to many of those who potentially would benefit due to barriers related to accessibility. While telerehabilitation is a promising strategy to support physical activity, there is a gap of knowledge regarding the implementation of technology that meet the needs of people post stroke or TIA in order to foster adherence and engagement in physical activity.Purpose is to improve health and wellbeing after stroke or TIA by increasing the access to physical activity through telerehabilitation. This will be accomplished by building on a national collaboration within secondary stroke prevention and through testing of an existing telerehabilitation program (ENAbLE) developed in Australia.The ENAbLE program seeks to strengthen physical functioning and self-efficacy for exercise through home-based physical exercise and to equip the person with knowledge and confidence to sustain physical activity through behavior change techniques. The program will be accessible via a recent developed mobile application which will be used to reinforce autonomy and patient-therapist partnership.We will first evaluate if the ENAbLE program can be delivered as intended through a pilot RCT to determine the feasibility, processes, end-users experiences and preliminary effects of the program in urban and rural regions of Sweden. We will thereafter initiate a full-scale RCT to investigate the effects of the ENAbLE program on risk factors for recurrent stroke, well-being and its cost-effectiveness across Sweden.The project will draw on socio-technical theory, depicting technologies as part of a dynamic system in order to explore its potential use in rehabilitation. The ENAbLE program offers a sustainable strategy to support exercise and physical activity which could benefit a large group of people with stroke and TIA regardless of where they live.
Forskningsbidrag
- Swedish Heart-Lung Foundation1 januari 2026 - 31 december 2028Background: The prevalence of stroke-related disability is expected to rise globally, significantly impacting families, healthcare systems, and economies. Although strong evidence supports the role of physical activity (PA) in improving health and preventing complications after stroke or transient ischemic attack (TIA), access to support for PA remains limited. When available, such support is often short-term and lacks the long-term personalization needed to sustain behavior change. Objective: This project investigates whether a personalized digital intervention (REACH) can enhance PA and health while reducing secondary complications in individuals post stroke or TIA. The specific objectives are to determine whether the REACH intervention: - Improves PA, physical functioning, well-being, and quality of life immediately after the intervention. - Reduces post-stroke complications and healthcare utilization for up to 5 years post-baseline. - Is cost-effective compared to standard care. We hypothesize that the REACH intervention will improve PA, functioning, well-being, and quality of lifereduce the incidence of recurrent stroke, comorbidities, mortality, and healthcare utilizationand be cost-effective, supporting large-scale implementation. Work Plan: In a multicenter Sequential Multiple Assignment Randomized Trial, 371 individuals post-stroke/TIA no longer receiving rehabilitation and with low PA will be randomized to one of two groups: - REACH, a 12-month mHealth intervention incorporating adaptive, personalized treatment trajectories, with physiotherapist-led support for exercise and self-management of PA. - Standard care, without active intervention. Recruitment and trial implementation will be conducted through an established clinical network across 5 Swedish regions. The primary outcome is steps per day, assessed via accelerometry immediately post-intervention. Stroke recurrence, comorbidity, mortality, and healthcare utilization will be tracked for up to 5 years using registry data. Cost-effectiveness will be evaluated through both within-trial and model-based economic analyses. Significance: If REACH improves PA and reduces the risk of secondary complications, it would represent a breakthrough in secondary stroke prevention, offering profound benefits for individuals, healthcare systems, and society. The cost-effectiveness analysis, combined with a scalable digital intervention model, will support national implementation.
- Vetenskapsrådet1 januari 2025 - 31 december 2026
- Swedish Research Council1 januari 2023 - 31 december 2026Life means combining motor-cognitive skills, e.g., walking, talking and navigating. Aging or neurological diseases, e.g., Parkinson’s disease (PD) compromises these skills needed for an independent life. It is uncertain which brain alterations lead to these difficulties and how to target these heterogenous motor-cognitive difficulties. Current treatments apply a "one-size-fits-all" approach, which needs to evolve towards personalized rehabilitation, reaching beyond a simple adaption to disease severity.Our multimodal project combines physiotherapy, neurology, psychology and neuroimaging to characterize motor-cognitive skills during complex walking, identify underlying brain alterations and subtype PD to inform a novel exercise approach for people with PD. This 5 years proposal has 4 stages: 1) Exploring brain alterations and links to the motor-cognitive skills in healthy and PD 2) PD subtyping using neuroimaging, motor, cognitive and clinical data 3) Characterization of exercise responsiveness in PD and 4) Development and testing of a personalized motor-cognitive exercise program. We combine novel techniques for data collection with in-depth analysis of existing data (EXPANd trial). The results will have an immediate application and clinical relevance for personalized rehabilitation in older and PD. There is no cure for PD yet, thus positive findings would revolutionize treatment, giving new hope to patients for a life with improved health, independence and higher quality.
- VINNOVA14 juni 2021 - 30 april 2023
- Fonds de Recherche du Québec - Santé1 april 2018 - 31 mars 2019
- Canadian Institutes of Health Research1 april 2017 - 31 mars 2018
- Fonds de Recherche du Québec - Santé1 april 2016 - 31 mars 2018
Anställningar
- Lektor, Fysioterapi, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2024-
- Biträdande Lektor, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2019-2024
- Universitetsadjunkt, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2016-2024
Examina och utbildning
- Docent, Fysioterapi, Karolinska Institutet, 2021
- Medicine Doktorsexamen, Institutionen för neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2016
- Medicine Magisterexamen, Karolinska Institutet, 2014
- Sjukgymnastexamen, Karolinska Institutet, 2008
Handledning
Handledning till doktorsexamen
- Lisa Sandberg, Physical activity in people with Parkinson’s disease –risk factors, exercise effects and connections to brain function, 2023-
- Alexander Kvist, Evaluating complex walking in aging and neurological disease: from motor behavior to brain activity, 2021-