Chiara Sorini

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: NATURE COMMUNICATIONS. 2024;15(1):1752

Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF.

Kvedaraite E; Lourda M; Mouratidou N; Düking T; Padhi A; Moll K; Czarnewski P; Sinha I; Xagoraris I; Kokkinou E; Damdimopoulos A; Weigel W; Hartwig O; Santos TE; Soini T; Van Acker A; Rahkonen N; Flodström Tullberg M; Ringqvist E; Buggert M; Jorns C; Lindforss U; Nordenvall C; Stamper CT; Unnersjö-Jess D; Akber M; Nadisauskaite R; Jansson J; Vandamme N; Sorini C; Grundeken ME; Rolandsdotter H; Rassidakis G; Villablanca EJ; Ideström M; Eulitz S; Arnell H; Mjösberg J; Henter J-I; Svensson M
Article: MUCOSAL IMMUNOLOGY. 2024;17(1):81-93

Intestinal damage is required for the pro-inflammatory differentiation of commensal CBir1-specific T cells.

Sorini C; Cardoso RF; Tripathi KP; Mold JE; Diaz OE; Holender Y; Kern BC; Czarnewski P; Gagliani N; Villablanca EJ
Journal article: JOURNAL OF CROHNS & COLITIS. 2024;18(Supplement_1):i332

P062 Characterization of UC1 and UC2 patients: towards personalized medicine in Ulcerative Colitis

Castillo F; Selin K; Fransson J; Sorini C; Hedin C; Villablanca E
Article: CELL REPORTS MEDICINE. 2023;4(5):101038

The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis.

Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Ideström M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjösberg J
Article: JCI INSIGHT. 2023;8(4):e161042

Metagenomic and single-cell RNA-Seq survey of the Helicobacter pylori-infected stomach in asymptomatic individuals.

Sorini C; Tripathi KP; Wu S; Higdon SM; Wang J; Cheng L; Banerjee S; Reinhardt A; Kreslavsky T; Thorell A; Engstrand L; Du J; Villablanca EJ
Article: IMMUNITY. 2022;55(12):2336-2351.e12

B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing.

Frede A; Czarnewski P; Monasterio G; Tripathi KP; Bejarano DA; Ramirez Flores RO; Sorini C; Larsson L; Luo X; Geerlings L; Novella-Rausell C; Zagami C; Kuiper R; Morales RA; Castillo F; Hunt M; Mariano LL; Hu YOO; Engblom C; Lennon-Duménil A-M; Mittenzwei R; Westendorf AM; Hövelmeyer N; Lundeberg J; Saez-Rodriguez J; Schlitzer A; Das S; Villablanca EJ
Article: BLOOD ADVANCES. 2022;6(15):4439-4449

Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors.

Wu C; Boey D; Bril O; Grootens J; Vijayabaskar MS; Sorini C; Ekoff M; Wilson NK; Ungerstedt JS; Nilsson G; Dahlin JS
Article: IMMUNITY. 2022;55(1):129-144.e8

Epithelial colonization by gut dendritic cells promotes their functional diversification.

Rivera CA; Randrian V; Richer W; Gerber-Ferder Y; Delgado M-G; Chikina AS; Frede A; Sorini C; Maurin M; Kammoun-Chaari H; Parigi SM; Goudot C; Cabeza-Cabrerizo M; Baulande S; Lameiras S; Guermonprez P; Reis e Sousa C; Lecuit M; Moreau HD; Helft J; Vignjevic DM; Villablanca EJ; Lennon-Duménil A-M
Article: DISEASE MODELS & MECHANISMS. 2021;14(12):dmm049104

Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation.

Diaz OE; Sorini C; Morales RA; Luo X; Frede A; Krais AM; Chávez MN; Wincent E; Das S; Villablanca EJ
Article: IMMUNITY. 2021;54(2):259-275.e7

Distinct developmental pathways from blood monocytes generate human lung macrophage diversity.

Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Gao Y; Sarhan D; Halle T; Sorini C; Lepzien R; Marquardt N; Michaëlsson J; Smed-Sörensen A; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2020;217(2):e20191155

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.

Phad GE; Pushparaj P; Tran K; Dubrovskaya V; Àdori M; Martinez-Murillo P; Vázquez Bernat N; Singh S; Dionne G; O'Dell S; Bhullar K; Narang S; Sorini C; Villablanca EJ; Sundling C; Murrell B; Mascola JR; Shapiro L; Pancera M; Martin M; Corcoran M; Wyatt RT; Karlsson Hedestam GB
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2019;197(3):263-275

Experimental colitis in IL-10-deficient mice ameliorates in the absence of PTPN22.

Jofra T; Galvani G; Cosorich I; De Giorgi L; Annoni A; Vecchione A; Sorini C; Falcone M; Fousteri G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(30):15140-15149

Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes.

Sorini C; Cosorich I; Lo Conte M; De Giorgi L; Facciotti F; Lucianò R; Rocchi M; Ferrarese R; Sanvito F; Canducci F; Falcone M
Article: NATURE COMMUNICATIONS. 2019;10(1):2892

Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification.

Czarnewski P; Parigi SM; Sorini C; Diaz OE; Das S; Gagliani N; Villablanca EJ
Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):178.8

Loss of gut barrier integrity triggers autoimmune diabetes through microbiota-induced activation of islet-reactive T cells

Falcone M; Sorini C; Cosorich I; Conte ML; Facciotti F; Sanvito F; Ferrarese R; Canducci F
Article: NATURE COMMUNICATIONS. 2018;9(1):5457

Molecular and functional heterogeneity of IL-10-producing CD4+ T cells.

Brockmann L; Soukou S; Steglich B; Czarnewski P; Zhao L; Wende S; Bedke T; Ergen C; Manthey C; Agalioti T; Geffken M; Seiz O; Parigi SM; Sorini C; Geginat J; Fujio K; Jacobs T; Roesch T; Izbicki JR; Lohse AW; Flavell RA; Krebs C; Gustafsson J-A; Antonson P; Roncarolo MG; Villablanca EJ; Gagliani N; Huber S
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1752

Increased iNKT17 Cell Frequency in the Intestine of Non-Obese Diabetic Mice Correlates With High Bacterioidales and Low Clostridiales Abundance.

De Giorgi L; Sorini C; Cosorich I; Ferrarese R; Canducci F; Falcone M
Article: SCIENCE ADVANCES. 2017;3(7):e1700492

High frequency of intestinal TH17 cells correlates with microbiota alterations and disease activity in multiple sclerosis.

Cosorich I; Dalla-Costa G; Sorini C; Ferrarese R; Messina MJ; Dolpady J; Radice E; Mariani A; Testoni PA; Canducci F; Comi G; Martinelli V; Falcone M
Article: CLINICAL IMMUNOLOGY. 2017;178:29-38

Mast cells contribute to autoimmune diabetes by releasing interleukin-6 and failing to acquire a tolerogenic IL-10+ phenotype.

Betto E; Usuelli V; Mandelli A; Badami E; Sorini C; Capolla S; Danelli L; Frossi B; Guarnotta C; Ingrao S; Tripodo C; Pucillo C; Gri G; Falcone M
Article: JOURNAL OF IMMUNOLOGY. 2016;197(8):3271-3280

MicroRNA-133b Regulation of Th-POK Expression and Dendritic Cell Signals Affect NKT17 Cell Differentiation in the Thymus.

Di Pietro C; De Giorgi L; Cosorich I; Sorini C; Fedeli M; Falcone M
Article: JOURNAL OF DIABETES RESEARCH. 2016;2016:7569431-12

Oral Probiotic VSL#3 Prevents Autoimmune Diabetes by Modulating Microbiota and Promoting Indoleamine 2,3-Dioxygenase-Enriched Tolerogenic Intestinal Environment.

Dolpady J; Sorini C; Di Pietro C; Cosorich I; Ferrarese R; Saita D; Clementi M; Canducci F; Falcone M
Article: AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2013;2(2):156-171

Shaping the (auto)immune response in the gut: the role of intestinal immune regulation in the prevention of type 1 diabetes.

Sorini C; Falcone M
Article: DIABETES. 2011;60(8):2120-2124

Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes.

Badami E; Sorini C; Coccia M; Usuelli V; Molteni L; Bolla AM; Scavini M; Mariani A; King C; Bosi E; Falcone M
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Conference publication: JOURNAL OF CROHNS & COLITIS. 2024;18:I328

Characterization of UC1 and UC2 patients: towards personalized medicine in Ulcerative Colitis

Castillo F; Selin K; Fransson J; Sorini C; Hedin C; Villablanca E
Preprint: MEDRXIV. 2021

Metagenomic and single-cell RNA-seq survey of the H. pylori-infected stomach in asymptomatic individuals

Sorini C; Tripathi K; Wu S; Higdon S; Wang J; Cheng L; Banerjee S; Reinhardt A; Kreslavsky T; Thorell A; Engstrand L; Du J; Villablanca E
Preprint: BIORXIV. 2021

Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

Wu C; Boey D; Bril O; Grootens J; Vijayabaskar MS; Sorini C; Ekoff M; Wilson N; Ungerstedt J; Nilsson G; Dahlin J
Editorial comment: IMMUNITY. 2021;54(6):1097-1099

ILC damage, and I'll repair it.

Sorini C; Villablanca EJ
Preprint: SSRN ELECTRONIC JOURNAL. 2021

B Cell Expansion Hinders the Stroma-Epithelium Regenerative Crosstalk During Mucosal Healing

Frede A; Tripathi KP; Czarnewski P; Monasterio G; Flores ROR; Sorini C; larsson L; Luo X; Novella-Rausell C; Zagami C; Hu YOO; Engblom C; Mittenzwei R; Hövelmeyer N; Lundeberg J; Das S; Saez-Rodriguez J; Villablanca EJ
Conference publication: JOURNAL OF CROHNS & COLITIS. 2019;13:S123

Conserved inflammatory profile between mice and humans allow unsupervised patient stratification and temporal allocation of IBD-risk genes

Czarnewski P; Parigi M; Diaz O; Das S; Sorini C; Gagliani N; Villablanca EJ
Preprint: BIORXIV. 2019

Conserved transcriptomic profile between mouse and human colitis allows temporal dynamic visualization of IBD-risk genes and unsupervised patient stratification

Czarnewski P; Parigi S; Sorini C; Diaz O; Das S; Gagliani N; Villablanca E
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:1937

How the Interplay Between the Commensal Microbiota, Gut Barrier Integrity, and Mucosal Immunity Regulates Brain Autoimmunity.

Antonini M; Lo Conte M; Sorini C; Falcone M
Review: FRONTIERS IN IMMUNOLOGY. 2018;9:2667

Commensal Bacteria-Specific CD4+ T Cell Responses in Health and Disease.

Sorini C; Cardoso RF; Gagliani N; Villablanca EJ
Editorial comment: CELLULAR & MOLECULAR IMMUNOLOGY. 2017;14(12):951-953

New therapeutic perspectives in Type 1 Diabetes: dietary interventions prevent β cell-autoimmunity by modifying the gut metabolic environment.

Sorini C; Cosorich I; Falcone M
Conference publication: DIABETOLOGIA. 2017;60:S121

Gut inflammation and mucus layer alterations trigger intestinal activation of islet-reactive T cells and autoimmune diabetes

Falcone M; Sorini C; Cosorich I; De Giorgi L; Luciano R; Rocchi M; Saita D; Ferrarese R; Canducci F; Sanvito F
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):268

Cholesterol metabolism shapes humoral responses in the intestinal mucosa

Sorini C; Parigi SM; Das S; Czarnewski P; Garimella M; Karlsson M; Villablanca EJ
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):293

Linking cholesterol metabolism and intestinal immunity through liver-X-receptor

Parigi SM; Das S; Barenco PVC; Sorini C; Perez OD; Antonson P; Gustafsson J-A; Villablanca EJ
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2015;22:201

The potential role of gut immunity in multiple sclerosis

Messina MJ; Falcone M; Mariani A; Sorini C; Testoni PA; Comi G; Martinelli V
Conference publication: IMMUNOLOGY. 2014;143:11

Chronic intestinal inflammation promotes autoimmune Type 1 Diabetes by altering gut mucosa-associated microbiota and favoring Th17 cell differentiation

Falcone M; Sorini C; Cosorich I; Canducci F; Saita D; Honda K
Review: AUTOIMMUNITY. 2011;44(1):11-22

The dangerous liaison between iNKT cells and dendritic cells: does it prevent or promote autoimmune diseases?

Caielli S; Sorini C; Falcone M

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