Aljona Maljukova

Publikationer
Populärvetenskap och samverkan

Artiklar

Journal article: GENOME BIOLOGY. 2024;25(1):143
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia
Malyukova A; Lahnalampi M; Falques-Costa T; Poeloenen P; Sipola M; Mehtonen J; Teppo S; Akopyan K; Viiliainen J; Lohi O; Hagstroem-Andersson AK; Heinaeniemi M; Sangfelt O
Article: ONCOIMMUNOLOGY. 2022;11(1):2109861
IFNγ directly counteracts imatinib-induced apoptosis of primary human CD34+CML stem/progenitor cells potentially through the upregulation of multiple key survival factors
Ujvari D; Malyukova A; Zovko A; Yektaei-Karin E; Madapura HS; Keszei M; Nagy N; Lotfi K; Bjorn N; Wallvik J; Stenke L; Salamon D
Article: CELL DEATH AND DISEASE. 2021;12(10):875
Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells
Malyukova A; Ujvari D; Yektaei-Karin E; Zovko A; Madapura HS; Keszei M; Nagy N; Lotfi K; Bjorn N; Wallvik J; Tamai M; Nguyen TTT; Akahane K; Inukai T; Stenke L; Salamon D
Journal article: FRONTIERS IN ONCOLOGY. 2021;11:758983
Editorial: Ubiquitin-Modifying Enzymes as Drug Targets and Biomarkers in Cancer
Bell JL; Malyukova A; Bertoldo JB; Summers MK; Sun Y
Article: GENOME MEDICINE. 2020;12(1):99
Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities
Mehtonen J; Teppo S; Lahnalampi M; Kokko A; Kaukonen R; Oksa L; Bouvy-Liivrand M; Malyukova A; Makinen A; Laukkanen S; Makinen PI; Rounioja S; Ruusuvuori P; Sangfelt O; Lund R; Lonnberg T; Lohi O; Heinaniemi M
Article: EMBO JOURNAL. 2016;35(20):2192-2212
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
Rahmanto AS; Savov V; Brunner A; Bolin S; Weishaupt H; Malyukova A; Rosen G; Cancer M; Hutter S; Sundstrom A; Kawauchi D; Jones DTW; Spruck C; Taylor MD; Cho Y-J; Pfister SM; Kool M; Korshunov A; Swartling FJ; Sangfelt O
Article: ONCOGENE. 2014;33(23):2987-2994
Histone deacetylase 5 blocks neuroblastoma cell differentiation by interacting with N-Myc.
Sun Y; Liu PY; Scarlett CJ; Malyukova A; Liu B; Marshall GM; MacKenzie KL; Biankin AV; Liu T
Article: EMBO MOLECULAR MEDICINE. 2013;5(7):1067-1086
CDK-mediated activation of the SCF^FBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
Cepeda D; Ng H-F; Sharifi HR; Mahmoudi S; Soto Cerrato V; Fredlund E; Magnusson K; Nilsson H; Malyukova A; Rantala J; Klevebring D; Vinals F; Bhaskaran N; Zakaria SM; Rahmanto AS; Grotegut S; Nielsen ML; Szigyarto CA-K; Sun D; Lerner M; Navani S; Widschwendter M; Uhlen M; Jirstrom K; Ponten F; Wohlschlegel J; Grander D; Spruck C; Larsson L-G; Sangfelt O
Article: LEUKEMIA. 2013;27(5):1053-1062
FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation
Malyukova A; Brown S; Papa R; O'Brien R; Giles J; Trahair TN; Dalla Pozza L; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Sangfelt O; Marshall GM
Article: CELL CYCLE. 2013;12(6):889-898
TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization.
Bell JL; Malyukova A; Kavallaris M; Marshall GM; Cheung BB
Article: CELL DEATH AND DIFFERENTIATION. 2013;20(3):503-514
The histone deacetylase SIRT2 stabilizes Myc oncoproteins.
Liu PY; Xu N; Malyukova A; Scarlett CJ; Sun YT; Zhang XD; Ling D; Su S-P; Nelson C; Chang DK; Koach J; Tee AE; Haber M; Norris MD; Toon C; Rooman I; Xue C; Cheung BB; Kumar S; Marshall GM; Biankin AV; Liu T
Article: JOURNAL OF PATHOLOGY. 2012;226(3):451-462
The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro.
Cheung BB; Koach J; Tan O; Kim P; Bell JL; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris M; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott JS; Cooper CL; Halliday GM; Scolyer RA; Marshall GM
Article: PLOS ONE. 2012;7(5):e37470
TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.
Bell JL; Malyukova A; Holien JK; Koach J; Parker MW; Kavallaris M; Marshall GM; Cheung BB
Article: ONCOGENE. 2010;29(46):6172-6183
TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells.
Marshall GM; Bell JL; Koach J; Tan O; Kim P; Malyukova A; Thomas W; Sekyere EO; Liu T; Cunningham AM; Tobias V; Norris MD; Haber M; Kavallaris M; Cheung BB
Article: MOLEKULYARNAYA BIOLOGIYA. 2009;43(6):1014-1018
Two CpG islands in the SEMA3B gene: Methylation in clear cell renal cell carcinoma
Loginov VI; Khodyrev DS; Pronina IV; Malyukova AV; Kazubskaya TP; Ermilova VD; Gar'kavtseva RF; Zabarovskii ER; Braga EA
Article: CANCER CELL. 2009;15(5):441-453
Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis
Grinkevich VV; Nikulenkov F; Shi Y; Enge M; Bao W; Maljukova A; Gluch A; Kel A; Sangfelt O; Selivanova G
Article: CELL CYCLE. 2008;7(8):1075-1082
Both SCF^Cdc4α and SCF^Cdc4γ are required for cyclin E turnover in cell lines that do not overexpress cyclin E
Sangfelt O; Cepeda D; Malyukova A; van Drogen F; Reed SI
Article: CANCER RESEARCH. 2007;67(19):9006-9012
FBXW7/hCDC4 is a general tumor suppressor in human cancer
Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Cepeda D; Fiegl H; Dofou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C
Article: EXPERIMENTAL CELL RESEARCH. 2007;313(14):3141-3152
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
Dohda T; Maljukova A; Liu L; Heyman M; Grander D; Brodin D; Sangfelt O; Lendahl U
Article: CANCER RESEARCH. 2007;67(12):5611-5616
The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling
Malyukova A; Dohda T; von der Lehr N; Akhondi S; Corcoran M; Heyman M; Spruck C; Grander D; Lendahl U; Sangfelt O
Article: MOLECULAR CELL. 2006;23(1):37-48
Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms
van Drogen F; Sangfelt O; Malyukova A; Matskova L; Yeh E; Means AR; Reed SI
Article: MOLEKULYARNAYA BIOLOGIYA. 2004;38(6):857-864
Methylation of the putative tumor suppressor gene RASSF1A in primary cervical tumors
Malyukova AV; Loginov WI; Hodyrev DS; Kadyrova EL; Pronina IV; Ivanova TA; Kisseljov FL; Zabarovsky ER; Kisseljova NP; Braga EA
Article: ONCOGENE. 2004;23(35):5941-5949
Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene
Li JF; Wang FL; Protopopov A; Malyukova A; Kashuba V; Minna JD; Lerman MI; Klein G; Zabarovsky E
Article: MOLEKULYARNAYA BIOLOGIYA. 2004;38(4):549-560
Methylation of the promoter region of the RASSF1A candidate tumor suppressor gene in primary epithelial tumors
Loginov VI; Malyukova AV; Seryogin YA; Hodyrev DS; Kazubskaya TP; Ermilova VD; Garkavtseva RF; Kisselev LL; Zabarovsky ER; Braga EA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(14):4906-4911
RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies
Kashuba VI; Li JF; Wang FL; Senchenko VN; Protopopov A; Malyukova A; Kutsenko AS; Kadyrova E; Zabarovska VI; Muravenko OV; Zelenin AV; Kisselev LL; Kuzmin I; Minna JD; Winberg G; Ernberg I; Braga E; Lerman MI; Klein G; Zabarovsky ER
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Corrigendum: CANCER RESEARCH. 2008;68(6):2051
The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling (vol 67, pg 5611, 2007)
Malyukova A; Dohda T; von der Lehr N; Akhoondi S; Corcoran M; Heyman M; Spruck C; Grander D; Lendahl U; Sangfelt O
Corrigendum: CANCER RESEARCH. 2008;68(4):1245
The FBXW7 gene is mutated in a variety of human tumors (vol 67, pg 9006, 2007)
Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Capeda D; Fiegl H; Dafou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C

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