Per Eriksson

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Per Eriksson är professor i kardiovaskulär medicin vid Karolinska Institutet sedan 2007. Hans forskning handlar om de underliggande molekylära mekanismerna för utvecklingen av aortaaneurysm (pulsåderbråck). Aortaaneurysm är en tyst sjukdom, som oftast märks först i det akuta läget vid aortadissektion eller rupturerad aorta. Båda tillstånden är dödliga om patienten inte opereras omedelbart.

Artiklar

Article: BMJ OPEN. 2024;14(3):e067977

Predictive machine learning models for ascending aortic dilatation in patients with bicuspid and tricuspid aortic valves undergoing cardiothoracic surgery: a prospective, single-centre and observational study.

Gaye B; Vignac M; Gådin JR; Ladouceur M; Caidahl K; Olsson C; Franco-Cereceda A; Eriksson P; Björck HM
Article: CARDIOVASCULAR RESEARCH. 2023;119(16):2594-2606

A machine learning based approach to identify carotid subclinical atherosclerosis endotypes.

Chen QS; Bergman O; Ziegler L; Baldassarre D; Veglia F; Tremoli E; Strawbridge RJ; Gallo A; Pirro M; Smit AJ; Kurl S; Savonen K; Lind L; Eriksson P; Gigante B
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.2030

Hemodynamics and plasma biomarkers in individuals with mild-to-moderate ascending aortic dilatation and tricuspid aortic valves

Hammareus F; Trenti C; Bjorck HM; Engvall J; Eriksson P; Lekedal H; Lundberg A; Nilsson L; Swahn E; Jonasson L; Dyverfeldt P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2023;101(10):1323-1333

SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?

Freiholtz D; Bergman O; Pradhananga S; Lång K; Poujade F-A; Granath C; Olsson C; Franco-Cereceda A; Sahlén P; Eriksson P; Björck HM
Article: CLINICAL PROTEOMICS. 2023;20(1):31

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases.

Carland C; Png G; Malarstig A; Kho PF; Gustafsson S; Michaelsson K; Lind L; Tsafantakis E; Karaleftheri M; Dedoussis G; Ramisch A; Macdonald-Dunlop E; Klaric L; Joshi PK; Chen Y; Björck HM; Eriksson P; Carrasco-Zanini J; Wheeler E; Suhre K; Gilly A; Zeggini E; Viñuela A; Dermitzakis ET; Wilson JF; Langenberg C; Thareja G; Halama A; Schmidt F; SCALLOP Consortium; Zanetti D; Assimes T
Article: JAMA CARDIOLOGY. 2023;8(8):721-731

Novel Association of the NOTCH Pathway Regulator MIB1 Gene With the Development of Bicuspid Aortic Valve.

Tessler I; Albuisson J; Piñeiro-Sabarís R; Verstraeten A; Kamber Kaya HE; Siguero-Álvarez M; Goudot G; MacGrogan D; Luyckx I; Shpitzen S; Levin G; Kelman G; Reshef N; Mananet H; Holdcraft J; Muehlschlegel JD; Peloso GM; Oppenheim O; Cheng C; Mazzella J-M; Andelfinger G; Mital S; Eriksson P; Billon C; Heydarpour M; Dietz HC; Jeunemaitre X; Leitersdorf E; Sprinzak D; Blacklow SC; Body SC; Carmi S; Loeys B; de la Pompa JL; Gilon D; Messas E; Durst R
Journal article: ATHEROSCLEROSIS. 2023;379:s54

BICUSPID AORTIC VALVE AORTOPATHY IS CHARACTERIZED BY EMBRYONIC ENDOTHELIAL TO MESENCHYMAL TRANSITION AND ENDOTHELIAL INSTABILITY

Freiholtz D; Bergman O; Lang K; Poujade F-A; Paloschi V; Granath C; Lindeman J; Olsson C; Franco-Cereceda A; Eriksson P; Bjorck HM
Journal article: ATHEROSCLEROSIS. 2023;379:s31

POSSIBLE ROLE OF SPP1 IN DEGENERATIVE ASCENDING AORTIC ANEURYSM FORMATION

Freiholtz D; Bergman O; Poujade F-A; Granath C; Lang K; Olsson C; Franco-Cereceda A; Bjorck HM; Eriksson P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2023;101(7):801-811

Bicuspid aortic valve aortopathy is characterized by embryonic epithelial to mesenchymal transition and endothelial instability.

Freiholtz D; Bergman O; Lång K; Poujade F-A; Paloschi V; Granath C; Lindeman JHN; Olsson C; Franco-Cereceda A; Eriksson P; Björck HM
Journal article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644

The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms

Zhang Y; Zhang Y; Hutterer E; Hultin S; Bergman O; Kolbeinsdottir S; Jin H; Forteza MJ; Ketelhuth DFJ; Roy J; Hedin U; Enge M; Matic L; Eriksson P; Holmgren L
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374

Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis.

Velásquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engström G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Lindén A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: ANNALS OF THORACIC SURGERY. 2022;114(5):1665-1670

Sex Differences in Aortopathy and Valve Diseases Among Patients Undergoing Cardiac Surgical Procedure.

Vignac M; Björck HM; Olsson C; Eriksson MJ; Jouven X; Michos ED; Franco-Cereceda A; Eriksson P; Gaye B
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2022;179(19):4709-4721

The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis.

Carracedo M; Pawelzik S-C; Artiach G; Pouwer MG; Plunde O; Saliba-Gustafsson P; Ehrenborg E; Eriksson P; Pieterman E; Stenke L; Princen HMG; Franco-Cereceda A; Bäck M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1151-1161

Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function.

Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Ottosson V; Forsberg D; Thorlacius GE; Biavati L; Strandberg L; Mofors J; Ramskold D; Ruhrmann S; Meneghel L; Nyberg W; Espinosa A; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Journal article: ATHEROSCLEROSIS. 2022;355:37

The role of rare enhancer variants in bicuspid aortic valve pathology

Zhigulev A; Lång K; Pradhananga S; Spalinskas R; Franco-Cereceda A; Björck H; Eriksson P; Sahlén P
Article: ATHEROSCLEROSIS. 2022;348:8-15

A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease.

Dang A-T; Turner AW; Lau P; Mohottalage D; Stephanie Fong YK; Eriksson P; Folkersen L; Matic L; Hedin U; Soubeyrand S; McPherson R
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(5):659-676

Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis.

Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42:a419

Therapeutic Potential Of The Proprotein Convertase Subtilisin/Kexin ( PCSK) Family In Vascular Disease

Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561

Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease.

Suur BE; Chemaly M; Lindquist Liljeqvist M; Djordjevic D; Stenemo M; Bergman O; Karlöf E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Article: BIOFACTORS. 2022;48(1):100-110

Neutrophil to lymphocyte ratio is not related to carotid atherosclerosis progression and cardiovascular events in the primary prevention of cardiovascular disease: Results from the IMPROVE study.

Mannarino MR; Bianconi V; Gigante B; Strawbridge RJ; Savonen K; Kurl S; Giral P; Smit A; Eriksson P; Tremoli E; Veglia F; Baldassarre D; Pirro M; IMPROVE study group
Article: JOURNAL OF VASCULAR SURGERY. 2021;74(6):2023-2029

Sex hormones in men with abdominal aortic aneurysm.

Villard C; Roy J; Bogdanovic M; Eriksson P; Hultgren R
Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(5):1061-1070

Arginase 1 is upregulated at admission in patients with ST-elevation myocardial infarction.

Tengbom J; Cederström S; Verouhis D; Böhm F; Eriksson P; Folkersen L; Gabrielsen A; Jernberg T; Lundman P; Persson J; Saleh N; Settergren M; Sörensson P; Tratsiakovich Y; Tornvall P; Jung C; Pernow J
Article: OPEN HEART. 2021;8(2):e001694

Interleukin 6 trans-signalling and the risk of future cardiovascular events in men and women.

Miri Y; Leander K; Eriksson P; Gigante B; Ziegler L
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):1109

Prenylcysteine oxidase 1, an emerging player in atherosclerosis.

Banfi C; Baetta R; Barbieri SS; Brioschi M; Guarino A; Ghilardi S; Sandrini L; Eligini S; Polvani G; Bergman O; Eriksson P; Tremoli E
Article: HEART. 2021;107(14):1167-1172

Relative survival after aortic valve surgery in patients with bicuspid aortic valves.

Glaser N; Jackson V; Eriksson P; Sartipy U; Franco-Cereceda A
Article: SCIENTIFIC REPORTS. 2021;11(1):7866

Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants.

Laguzzi F; Maitusong B; Strawbridge RJ; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; Kurl S; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K; IMPROVE Study group
Article: CARDIOVASCULAR ULTRASOUND. 2021;19(1):14

Pre- and postoperative left atrial and ventricular volumetric and deformation analyses in severe aortic regurgitation.

Jenner J; Ilami A; Petrini J; Eriksson P; Franco-Cereceda A; Eriksson MJ; Caidahl K
Article: SCIENTIFIC REPORTS. 2021;11(1):632

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals.

Strawbridge RJ; Johnston KJA; Bailey MES; Baldassarre D; Cullen B; Eriksson P; deFaire U; Ferguson A; Gigante B; Giral P; Graham N; Hamsten A; Humphries SE; Kurl S; Lyall DM; Lyall LM; Pell JP; Pirro M; Savonen K; Smit AJ; Tremoli E; Tomainen T-P; Veglia F; Ward J; Sennblad B; Smith DJ
Article: NATURE COMMUNICATIONS. 2021;12(1):24

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V; Mägi R; Hottenga J-J; Grallert H; Perry JRB; Bouatia-Naji N; Marullo L; Rybin D; Jansen R; Min JL; Dimas AS; Ulrich A; Zudina L; Gådin JR; Jiang L; Faggian A; Bonnefond A; Fadista J; Stathopoulou MG; Isaacs A; Willems SM; Navarro P; Tanaka T; Jackson AU; Montasser ME; O'Connell JR; Bielak LF; Webster RJ; Saxena R; Stafford JM; Pourcain BS; Timpson NJ; Salo P; Shin S-Y; Amin N; Smith AV; Li G; Verweij N; Goel A; Ford I; Johnson PCD; Johnson T; Kapur K; Thorleifsson G; Strawbridge RJ; Rasmussen-Torvik LJ; Esko T; Mihailov E; Fall T; Fraser RM; Mahajan A; Kanoni S; Giedraitis V; Kleber ME; Silbernagel G; Meyer J; Müller-Nurasyid M; Ganna A; Sarin A-P; Yengo L; Shungin D; Luan J; Horikoshi M; An P; Sanna S; Boettcher Y; Rayner NW; Nolte IM; Zemunik T; Iperen EV; Kovacs P; Hastie ND; Wild SH; McLachlan S; Campbell S; Polasek O; Carlson O; Egan J; Kiess W; Willemsen G; Kuusisto J; Laakso M; Dimitriou M; Hicks AA; Rauramaa R; Bandinelli S; Thorand B; Liu Y; Miljkovic I; Lind L; Doney A; Perola M; Hingorani A; Kivimaki M; Kumari M; Bennett AJ; Groves CJ; Herder C; Koistinen HA; Kinnunen L; Faire UD; Bakker SJL; Uusitupa M; Palmer CNA; Jukema JW; Sattar N; Pouta A; Snieder H; Boerwinkle E; Pankow JS; Magnusson PK; Krus U; Scapoli C; de Geus EJCN; Blüher M; Wolffenbuttel BHR; Province MA; Abecasis GR; Meigs JB; Hovingh GK; Lindström J; Wilson JF; Wright AF; Dedoussis GV; Bornstein SR; Schwarz PEH; Tönjes A; Winkelmann BR; Boehm BO; März W; Metspalu A; Price JF; Deloukas P; Körner A; Lakka TA; Keinanen-Kiukaanniemi SM; Saaristo TE; Bergman RN; Tuomilehto J; Wareham NJ; Langenberg C; Männistö S; Franks PW; Hayward C; Vitart V; Kaprio J; Visvikis-Siest S; Balkau B; Altshuler D; Rudan I; Stumvoll M; Campbell H; van Duijn CM; Gieger C; Illig T; Ferrucci L; Pedersen NL; Pramstaller PP; Boehnke M; Frayling TM; Shuldiner AR; Peyser PA; Kardia SLR; Palmer LJ; Penninx BW; Meneton P; Harris TB; Navis G; Harst PVD; Smith GD; Forouhi NG; Loos RJF; Salomaa V; Soranzo N; Boomsma DI; Groop L; Tuomi T; Hofman A; Munroe PB; Gudnason V; Siscovick DS; Watkins H; Lecoeur C; Vollenweider P; Franco-Cereceda A; Eriksson P; Jarvelin M-R; Stefansson K; Hamsten A; Nicholson G; Karpe F; Dermitzakis ET; Lindgren CM; McCarthy MI; Froguel P; Kaakinen MA; Lyssenko V; Watanabe RM; Ingelsson E; Florez JC; Dupuis J; Barroso I; Morris AP; Prokopenko I; Meta-Analyses of Glucose and Insulin-related trait
Journal article: ATHEROSCLEROSIS. 2020;315:e22-e23

Repression of MAP1LC3A during atherosclerosis progression plays an important role in the regulation of vascular smooth muscle cell phenotype

Ehrenborg E; Paloschi V; Goncalves I; Saliba-Gustafsson P; Werngren O; Matic L; Skogsberg J; Jin H; Ketelhuth DFJ; Maegdefessel L; Hedin U; Eriksson P; Magné J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2020;40(11):2700-2713

Tunica-Specific Transcriptome of Abdominal Aortic Aneurysm and the Effect of Intraluminal Thrombus, Smoking, and Diameter Growth Rate.

Lindquist Liljeqvist M; Hultgren R; Bergman O; Villard C; Kronqvist M; Eriksson P; Roy J
Article: GENES. 2020;11(11):E1243-1243

Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study.

Castaldo L; Laguzzi F; Strawbridge RJ; Baldassarre D; Veglia F; Vigo L; Tremoli E; de Faire U; Eriksson P; Smit AJ; Aubrecht J; Leander K; Pirro M; Giral P; Ritieni A; Di Minno G; Mälarstig A; Gigante B
Article: CELLULAR IMMUNOLOGY. 2020;355:104148

Promoter anchored interaction landscape of THP-1 macrophages captures early immune response processes.

Pradhananga S; Spalinskas R; Poujade F-A; Eriksson P; Sahlén P
Article: CELLS. 2020;9(7):E1710-1710

TLR7 Expression Is Associated with M2 Macrophage Subset in Calcific Aortic Valve Stenosis.

Karadimou G; Plunde O; Pawelzik S-C; Carracedo M; Eriksson P; Franco-Cereceda A; Paulsson-Berne G; Bäck M
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2020;13(3):e002710-148

FADS1 (Fatty Acid Desaturase 1) Genotype Associates With Aortic Valve FADS mRNA Expression, Fatty Acid Content and Calcification.

Plunde O; Larsson SC; Artiach G; Thanassoulis G; Carracedo M; Franco-Cereceda A; Eriksson P; Bäck M
Article: CIRCULATION RESEARCH. 2020;126(5):571-585

PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.

Rykaczewska U; Suur BE; Röhl S; Razuvaev A; Lengquist M; Sabater-Lleal M; van der Laan SW; Miller CL; Wirka RC; Kronqvist M; Gonzalez Diez M; Vesterlund M; Gillgren P; Odeberg J; Lindeman JH; Veglia F; Humphries SE; de Faire U; Baldassarre D; Tremoli E; IMPROVE study group; Lehtiö J; Hansson GK; Paulsson-Berne G; Pasterkamp G; Quertermous T; Hamsten A; Eriksson P; Hedin U; Matic L
Article: GENES AND IMMUNITY. 2020;21(2):100-108

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A; Veglia F; Baldassarre D; Strawbridge RJ; Golabkesh Z; Sennblad B; Leander K; Smit AJ; Giral P; Humphries SE; Tremoli E; Hamsten A; de Faire U; Gigante B; on behalf of the IMPROVE study group
Article: JVS-VASCULAR SCIENCE. 2020;1:13-27

Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.

Röhl S; Rykaczewska U; Seime T; Suur BE; Diez MG; Gådin JR; Gainullina A; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JHN; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Matic LP
Article: NATURE GENETICS. 2020;52(1):40-47

Loss of ADAMTS19 causes progressive non-syndromic heart valve disease.

Wünnemann F; Ta-Shma A; Preuss C; Leclerc S; van Vliet PP; Oneglia A; Thibeault M; Nordquist E; Lincoln J; Scharfenberg F; Becker-Pauly C; Hofmann P; Hoff K; Audain E; Kramer H-H; Makalowski W; Nir A; Gerety SS; Hurles M; Comes J; Fournier A; Osinska H; Robins J; Pucéat M; MIBAVA Leducq Consortium principal investigators; Elpeleg O; Hitz M-P; Andelfinger G
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2020;15:6137-6152

Molecular Imaging of Inflammation in a Mouse Model of Atherosclerosis Using a Zirconium-89-Labeled Probe.

Ahmed M; Tegnebratt T; Tran TA; Lu L; Damberg P; Gisterå A; Tarnawski L; Bone D; Hedin U; Eriksson P; Holmin S; Gustafsson B; Caidahl K
Article: JOURNAL OF INTERNAL MEDICINE. 2020;287(1):66-77

New candidate genes for ST-elevation myocardial infarction.

Cederström S; Lundman P; Folkersen L; Paulsson-Berne G; Karadimou G; Eriksson P; Caidahl K; Gabrielsen A; Jernberg T; Persson J; Tornvall P
Journal article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2019;58(6):e70-e71

Elastase Fibrinolysis as a Marker of Presence, Size and Mechanical Stress of Abdominal Aortic Aneurysms and its Intraluminal Thrombi

Liljeqvist ML; Hultgren R; Silveira A; Eriksson P; Roy J
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2019;137:1-8

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.

Klevstig M; Arif M; Mannila M; Svedlund S; Mardani I; Ståhlman M; Andersson L; Lindbom M; Miljanovic A; Franco-Cereceda A; Eriksson P; Jeppsson A; Gan L-M; Levin M; Mardinoglu A; Ehrenborg E; Borén J
Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(6):660-675

Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy.

Saliba-Gustafsson P; Pedrelli M; Gertow K; Werngren O; Janas V; Pourteymour S; Baldassarre D; Tremoli E; Veglia F; Rauramaa R; Smit AJ; Giral P; Kurl S; Pirro M; de Faire U; Humphries SE; Hamsten A; IMPROVE Study Group; Gonçalves I; Orho-Melander M; Franco-Cereceda A; Borén J; Eriksson P; Magné J; Parini P; Ehrenborg E
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2019;17(11):1808-1814

A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process.

Thibord F; Hardy L; Ibrahim-Kosta M; Saut N; Pulcrano-Nicolas A-S; Goumidi L; Civelek M; Eriksson P; Deleuze J-F; Le Goff W; Trégouët D-A; Morange P-E
Article: EUROPEAN HEART JOURNAL. 2019;40(30):2495-2503

Prevention of radiotherapy-induced arterial inflammation by interleukin-1 blockade.

Christersdottir T; Pirault J; Gisterå A; Bergman O; Gallina AL; Baumgartner R; Lundberg AM; Eriksson P; Yan Z-Q; Paulsson-Berne G; Hansson GK; Olofsson PS; Halle M
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2019;27(7):1033-1043

Copy number variation analysis in bicuspid aortic valve-related aortopathy identifies TBX20 as a contributing gene.

Luyckx I; Kumar AA; Reyniers E; Dekeyser E; Vanderstraeten K; Vandeweyer G; Wünnemann F; Preuss C; Mazzella J-M; Goudot G; Messas E; Albuisson J; Jeunemaitre X; Eriksson P; Mohamed SA; Kempers M; Salemink S; Duijnhouwer A; Andelfinger G; Dietz HC; Verstraeten A; Van Laer L; Loeys BL; MIBAVA Leducq Consortium
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(6):E1486-1486

Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells.

Carracedo M; Persson O; Saliba-Gustafsson P; Artiach G; Ehrenborg E; Eriksson P; Franco-Cereceda A; Bäck M
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;278:65-69

Comparison of biomechanical properties in ascending aortic aneurysms of patients with congenital bicuspid aortic valve and Marfan syndrome.

Yan J; Lehsau A-C; Sauer B; Pieper B; Mohamed SA; Mechanistic Interrogation of Bicuspid Aortic Valve
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2019;12(3):e002353

High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways.

Åkerborg Ö; Spalinskas R; Pradhananga S; Anil A; Höjer P; Poujade F-A; Folkersen L; Eriksson PP; Sahlén P
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;276:212-217

Effects of the coronary artery disease associated LPA and 9p21 loci on risk of aortic valve stenosis.

Trenkwalder T; Nelson CP; Musameh MD; Mordi IR; Kessler T; Pellegrini C; Debiec R; Rheude T; Lazovic V; Zeng L; Martinsson A; Gustav Smith J; Gådin JR; Franco-Cereceda A; Eriksson P; Nielsen JB; Graham SE; Willer CJ; Hveem K; Kastrati A; Braund PS; Palmer CNA; Aracil A; Husser O; Koenig W; Schunkert H; Lang CC; Hengstenberg C; Samani NJ
Article: PLOS ONE. 2019;14(6):e0217765

Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq.

Gådin JR; Buil A; Colantuoni C; Jaffe AE; Nielsen J; Shin J-H; Hyde TM; Kleinman JE; BrainSeq Consortium; Plath N; Eriksson P; Brunak S; Didriksen M; Weinberger DR; Folkersen L
Article: NATURE GENETICS. 2019;51(1):42-50

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm.

Gould RA; Aziz H; Woods CE; Seman-Senderos MA; Sparks E; Preuss C; Wünnemann F; Bedja D; Moats CR; McClymont SA; Rose R; Sobreira N; Ling H; MacCarrick G; Kumar AA; Luyckx I; Cannaerts E; Verstraeten A; Björk HM; Lehsau A-C; Jaskula-Ranga V; Lauridsen H; Shah AA; Bennett CL; Ellinor PT; Lin H; Isselbacher EM; Lino Cardenas CL; Butcher JT; Hughes GC; Lindsay ME; Baylor-Hopkins Center for Mendelian Genomics; MIBAVA Leducq Consortium; Mertens L; Franco-Cereceda A; Verhagen JMA; Wessels M; Mohamed SA; Eriksson P; Mital S; Van Laer L; Loeys BL; Andelfinger G; McCallion AS; Dietz HC
Article: JOURNAL OF INTERNAL MEDICINE. 2019;285(1):102-114

The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves.

Maleki S; Cottrill KA; Poujade F-A; Bhattachariya A; Bergman O; Gådin JR; Simon N; Lundströmer K; Franco-Cereceda A; Björck HM; Chan SY; Eriksson P
Article: BLOOD. 2018;132(17):1842-1850

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis.

Ward-Caviness CK; Huffman JE; Everett K; Germain M; van Dongen J; Hill WD; Jhun MA; Brody JA; Ghanbari M; Du L; Roetker NS; de Vries PS; Waldenberger M; Gieger C; Wolf P; Prokisch H; Koenig W; O'Donnell CJ; Levy D; Liu C; Truong V; Wells PS; Trégouët D-A; Tang W; Morrison AC; Boerwinkle E; Wiggins KL; McKnight B; Guo X; Psaty BM; Sotoodenia N; Boomsma DI; Willemsen G; Ligthart L; Deary IJ; Zhao W; Ware EB; Kardia SLR; Van Meurs JBJ; Uitterlinden AG; Franco OH; Eriksson P; Franco-Cereceda A; Pankow JS; Johnson AD; Gagnon F; Morange P-E; de Geus EJC; Starr JM; Smith JA; Dehghan A; Björck HM; Smith NL; Peters A
Article: CIRCULATION. 2018;138(15):1551-1568

H19 Induces Abdominal Aortic Aneurysm Development and Progression.

Li DY; Busch A; Jin H; Chernogubova E; Pelisek J; Karlsson J; Sennblad B; Liu S; Lao S; Hofmann P; Bäcklund A; Eken SM; Roy J; Eriksson P; Dacken B; Ramanujam D; Dueck A; Engelhardt S; Boon RA; Eckstein H-H; Spin JM; Tsao PS; Maegdefessel L
Article: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 2018;10:17-28

Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis.

Aldi S; Matic LP; Hamm G; van Keulen D; Tempel D; Holmstrøm K; Szwajda A; Nielsen BS; Emilsson V; Ait-Belkacem R; Lengquist M; Paulsson-Berne G; Eriksson P; Lindeman JHN; Gool AJ; Stauber J; Hedin U; Hurt-Camejo E
Article: ATHEROSCLEROSIS SUPPLEMENTS. 2018;35:e6-e13

Notch, BMP and WNT/β-catenin network is impaired in endothelial cells of the patients with thoracic aortic aneurysm.

Kostina A; Bjork H; Ignatieva E; Irtyuga O; Uspensky V; Semenova D; Maleki S; Tomilin A; Moiseeva O; Franco-Cereceda A; Gordeev M; Faggian G; Kostareva A; Eriksson P; Malashicheva A
Article: NATURE COMMUNICATIONS. 2018;9(1):987

Genome-wide analysis yields new loci associating with aortic valve stenosis.

Helgadottir A; Thorleifsson G; Gretarsdottir S; Stefansson OA; Tragante V; Thorolfsdottir RB; Jonsdottir I; Bjornsson T; Steinthorsdottir V; Verweij N; Nielsen JB; Zhou W; Folkersen L; Martinsson A; Heydarpour M; Prakash S; Oskarsson G; Gudbjartsson T; Geirsson A; Olafsson I; Sigurdsson EL; Almgren P; Melander O; Franco-Cereceda A; Hamsten A; Fritsche L; Lin M; Yang B; Hornsby W; Guo D; Brummett CM; Abecasis G; Mathis M; Milewicz D; Body SC; Eriksson P; Willer CJ; Hveem K; Newton-Cheh C; Smith JG; Danielsen R; Thorgeirsson G; Thorsteinsdottir U; Gudbjartsson DF; Holm H; Stefansson K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(8):1907-1912

Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm.

Di Gennaro A; Araújo AC; Busch A; Jin H; Wågsäter D; Vorkapic E; Caidahl K; Eriksson P; Samuelsson B; Maegdefessel L; Haeggström JZ
Article: SCIENTIFIC REPORTS. 2018;8(1):2777

Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve.

Björck HM; Du L; Pulignani S; Paloschi V; Lundströmer K; Kostina AS; Österholm C; Malashicheva A; Kostareva A; Evangelista A; Teixidó-Tura G; Maleki S; Franco-Cereceda A; Eriksson P; Mechanistic Interrogation of Bicuspid Aortic Valve
Article: THROMBOSIS AND HAEMOSTASIS. 2018;118(2):329-339

Neutrophil Elastase-Derived Fibrin Degradation Products Indicate Presence of Abdominal Aortic Aneurysms and Correlate with Intraluminal Thrombus Volume.

Lindquist Liljeqvist M; Silveira A; Hultgren R; Frebelius S; Lengquist M; Engström J; Gasser TC; Eriksson P; Roy J
Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444

Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.

Mahdessian H; Perisic Matic L; Lengquist M; Gertow K; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Hamsten A; Eriksson P; Hedin U; Mälarstig A; IMPROVE study group
Article: KIDNEY INTERNATIONAL REPORTS. 2017;2(6):1208-1218

Altered Protein Composition of Subcutaneous Adipose Tissue in Chronic Kidney Disease.

Gertow J; Ng CZ; Mamede Branca RM; Werngren O; Du L; Kjellqvist S; Hemmingsson P; Bruchfeld A; MacLaughlin H; Eriksson P; Axelsson J; Fisher RM
Article: BIOINFORMATICS. 2017;33(19):3126-3128

ClusterSignificance: a bioconductor package facilitating statistical analysis of class cluster separations in dimensionality reduced data.

Serviss JT; Gådin JR; Eriksson P; Folkersen L; Grandér D
Article: HISTOCHEMISTRY AND CELL BIOLOGY. 2017;148(4):425-433

Vessel wall morphology is equivalent for different artery types and localizations of advanced human aneurysms.

Busch A; Grimm C; Hartmann E; Paloschi V; Kickuth R; Lengquist M; Otto C; Eriksson P; Kellersmann R; Lorenz U; Maegdefessel L
Article: JOURNAL OF VASCULAR SURGERY. 2017;66(2):579-585.e1

The composition of collagen in the aneurysm wall of men and women.

Villard C; Eriksson P; Hanemaaijer R; Lindeman JH; Hultgren R
Article: NATURE COMMUNICATIONS. 2017;8:15481

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve.

Yang B; Zhou W; Jiao J; Nielsen JB; Mathis MR; Heydarpour M; Lettre G; Folkersen L; Prakash S; Schurmann C; Fritsche L; Farnum GA; Lin M; Othman M; Hornsby W; Driscoll A; Levasseur A; Thomas M; Farhat L; Dubé M-P; Isselbacher EM; Franco-Cereceda A; Guo D-C; Bottinger EP; Deeb GM; Booher A; Kheterpal S; Chen YE; Kang HM; Kitzman J; Cordell HJ; Keavney BD; Goodship JA; Ganesh SK; Abecasis G; Eagle KA; Boyle AP; Loos RJF; Eriksson P; Tardif J-C; Brummett CM; Milewicz DM; Body SC; Willer CJ
Article: PLOS GENETICS. 2017;13(4):e1006706

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

Folkersen L; Fauman E; Sabater-Lleal M; Strawbridge RJ; Frånberg M; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Enroth S; Johansson Å; Enroth SB; Gustafsson S; Lind L; Lindgren C; Morris AP; Giedraitis V; Silveira A; Franco-Cereceda A; Tremoli E; IMPROVE study group; Gyllensten U; Ingelsson E; Brunak S; Eriksson P; Ziemek D; Hamsten A; Mälarstig A
Article: CIRCULATION RESEARCH. 2017;120(4):633-644

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions.

Eken SM; Jin H; Chernogubova E; Li Y; Simon N; Sun C; Korzunowicz G; Busch A; Bäcklund A; Österholm C; Razuvaev A; Renné T; Eckstein HH; Pelisek J; Eriksson P; González Díez M; Perisic Matic L; Schellinger IN; Raaz U; Leeper NJ; Hansson GK; Paulsson-Berne G; Hedin U; Maegdefessel L
Article: MATURITAS. 2017;96:39-44

Differential expression of sex hormone receptors in abdominal aortic aneurysms.

Villard C; Eriksson P; Kronqvist M; Lengquist M; Jorns C; Hartman J; Roy J; Hultgren R
Article: HUMAN MOLECULAR GENETICS. 2017;26(3):637-649

Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.

Sennblad B; Basu S; Mazur J; Suchon P; Martinez-Perez A; van Hylckama Vlieg A; Truong V; Li Y; Gådin JR; Tang W; Grossman V; de Haan HG; Handin N; Silveira A; Souto JC; Franco-Cereceda A; Morange P-E; Gagnon F; Soria JM; Eriksson P; Hamsten A; Maegdefessel L; Rosendaal FR; Wild P; Folsom AR; Trégouët D-A; Sabater-Lleal M
Article: CIRCULATION RESEARCH. 2017;120(2):341-353

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Jones GT; Tromp G; Kuivaniemi H; Gretarsdottir S; Baas AF; Giusti B; Strauss E; Van't Hof FNG; Webb TR; Erdman R; Ritchie MD; Elmore JR; Verma A; Pendergrass S; Kullo IJ; Ye Z; Peissig PL; Gottesman O; Verma SS; Malinowski J; Rasmussen-Torvik LJ; Borthwick KM; Smelser DT; Crosslin DR; de Andrade M; Ryer EJ; McCarty CA; Böttinger EP; Pacheco JA; Crawford DC; Carrell DS; Gerhard GS; Franklin DP; Carey DJ; Phillips VL; Williams MJA; Wei W; Blair R; Hill AA; Vasudevan TM; Lewis DR; Thomson IA; Krysa J; Hill GB; Roake J; Merriman TR; Oszkinis G; Galora S; Saracini C; Abbate R; Pulli R; Pratesi C; Saratzis A; Verissimo AR; Bumpstead S; Badger SA; Clough RE; Cockerill G; Hafez H; Scott DJA; Futers TS; Romaine SPR; Bridge K; Griffin KJ; Bailey MA; Smith A; Thompson MM; van Bockxmeer FM; Matthiasson SE; Thorleifsson G; Thorsteinsdottir U; Blankensteijn JD; Teijink JAW; Wijmenga C; de Graaf J; Kiemeney LA; Lindholt JS; Hughes A; Bradley DT; Stirrups K; Golledge J; Norman PE; Powell JT; Humphries SE; Hamby SE; Goodall AH; Nelson CP; Sakalihasan N; Courtois A; Ferrell RE; Eriksson P; Folkersen L; Franco-Cereceda A; Eicher JD; Johnson AD; Betsholtz C; Ruusalepp A; Franzén O; Schadt EE; Björkegren JLM; Lipovich L; Drolet AM; Verhoeven EL; Zeebregts CJ; Geelkerken RH; van Sambeek MR; van Sterkenburg SM; de Vries J-P; Stefansson K; Thompson JR; de Bakker PIW; Deloukas P; Sayers RD; Harrison SC; van Rij AM; Samani NJ; Bown MJ
Article: DIABETOLOGY & METABOLIC SYNDROME. 2017;9:79

Elevated circulating fasting glucagon-like peptide-1 in surgical patients with aortic valve disease and diabetes.

Krizhanovskii C; Ntika S; Olsson C; Eriksson P; Franco-Cereceda A
Article: FRONTIERS IN PHYSIOLOGY. 2017;8:400

Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor.

Gillis E; Kumar AA; Luyckx I; Preuss C; Cannaerts E; van de Beek G; Wieschendorf B; Alaerts M; Bolar N; Vandeweyer G; Meester J; Wünnemann F; Gould RA; Zhurayev R; Zerbino D; Mohamed SA; Mital S; Mertens L; Björck HM; Franco-Cereceda A; McCallion AS; Van Laer L; Verhagen JMA; van de Laar IMBH; Wessels MW; Messas E; Goudot G; Nemcikova M; Krebsova A; Kempers M; Salemink S; Duijnhouwer T; Jeunemaitre X; Albuisson J; Eriksson P; Andelfinger G; Dietz HC; Verstraeten A; Loeys BL; Mibava Leducq Consortium
Article: DISEASE MARKERS. 2017;2017:1096916-10

Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22.

Beaney KE; Smith AJP; Folkersen L; Palmen J; Wannamethee SG; Jefferis BJ; Whincup P; Gaunt TR; Casas JP; Ben-Shlomo Y; Price JF; Kumari M; Wong A; Ong K; Hardy R; Kuh D; Wareham N; Kivimaki M; Eriksson P; Humphries SE; Consortium U
Article: EUROPEAN HEART JOURNAL. 2016;37(47):3532-3535

Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis.

Laguna-Fernandez A; Carracedo M; Jeanson G; Nagy E; Eriksson P; Caligiuri G; Franco-Cereceda A; Bäck M
Article: SCIENTIFIC REPORTS. 2016;6:35712

Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves.

Maleki S; Kjellqvist S; Paloschi V; Magné J; Branca RMM; Du L; Hultenby K; Petrini J; Fuxe J; MIBAVA Leducq Consortium; Lehtiö J; Franco-Cereceda A; Eriksson P; Björck HM
Article: NATURE MEDICINE. 2016;22(10):1140-1150

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.

Stellos K; Gatsiou A; Stamatelopoulos K; Perisic Matic L; John D; Lunella FF; Jaé N; Rossbach O; Amrhein C; Sigala F; Boon RA; Fürtig B; Manavski Y; You X; Uchida S; Keller T; Boeckel J-N; Franco-Cereceda A; Maegdefessel L; Chen W; Schwalbe H; Bindereif A; Eriksson P; Hedin U; Zeiher AM; Dimmeler S
Article: NATURE GENETICS. 2016;48(10):1171-1184

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Ehret GB; Ferreira T; Chasman DI; Jackson AU; Schmidt EM; Johnson T; Thorleifsson G; Luan J; Donnelly LA; Kanoni S; Petersen A-K; Pihur V; Strawbridge RJ; Shungin D; Hughes MF; Meirelles O; Kaakinen M; Bouatia-Naji N; Kristiansson K; Shah S; Kleber ME; Guo X; Lyytikäinen L-P; Fava C; Eriksson N; Nolte IM; Magnusson PK; Salfati EL; Rallidis LS; Theusch E; Smith AJP; Folkersen L; Witkowska K; Pers TH; Joehanes R; Kim SK; Lataniotis L; Jansen R; Johnson AD; Warren H; Kim YJ; Zhao W; Wu Y; Tayo BO; Bochud M; CHARGE-EchoGen consortium; CHARGE-HF consortium; Wellcome Trust Case Control Consortium; Absher D; Adair LS; Amin N; Arking DE; Axelsson T; Baldassarre D; Balkau B; Bandinelli S; Barnes MR; Barroso I; Bevan S; Bis JC; Bjornsdottir G; Boehnke M; Boerwinkle E; Bonnycastle LL; Boomsma DI; Bornstein SR; Brown MJ; Burnier M; Cabrera CP; Chambers JC; Chang I-S; Cheng C-Y; Chines PS; Chung R-H; Collins FS; Connell JM; Döring A; Dallongeville J; Danesh J; de Faire U; Delgado G; Dominiczak AF; Doney ASF; Drenos F; Edkins S; Eicher JD; Elosua R; Enroth S; Erdmann J; Eriksson P; Esko T; Evangelou E; Evans A; Fall T; Farrall M; Felix JF; Ferrières J; Ferrucci L; Fornage M; Forrester T; Franceschini N; Duran OHF; Franco-Cereceda A; Fraser RM; Ganesh SK; Gao H; Gertow K; Gianfagna F; Gigante B; Giulianini F; Goel A; Goodall AH; Goodarzi MO; Gorski M; Gräßler J; Groves C; Gudnason V; Gyllensten U; Hallmans G; Hartikainen A-L; Hassinen M; Havulinna AS; Hayward C; Hercberg S; Herzig K-H; Hicks AA; Hingorani AD; Hirschhorn JN; Hofman A; Holmen J; Holmen OL; Hottenga J-J; Howard P; Hsiung CA; Hunt SC; Ikram MA; Illig T; Iribarren C; Jensen RA; Kähönen M; Kang H; Kathiresan S; Keating BJ; Khaw K-T; Kim YK; Kim E; Kivimaki M; Klopp N; Kolovou G; Komulainen P; Kooner JS; Kosova G; Krauss RM; Kuh D; Kutalik Z; Kuusisto J; Kvaløy K; Lakka TA; Lee NR; Lee I-T; Lee W-J; Levy D; Li X; Liang K-W; Lin H; Lin L; Lindström J; Lobbens S; Männistö S; Müller G; Müller-Nurasyid M; Mach F; Markus HS; Marouli E; McCarthy MI; McKenzie CA; Meneton P; Menni C; Metspalu A; Mijatovic V; Moilanen L; Montasser ME; Morris AD; Morrison AC; Mulas A; Nagaraja R; Narisu N; Nikus K; O'Donnell CJ; O'Reilly PF; Ong KK; Paccaud F; Palmer CD; Parsa A; Pedersen NL; Penninx BW; Perola M; Peters A; Poulter N; Pramstaller PP; Psaty BM; Quertermous T; Rao DC; Rasheed A; Rayner NWNWR; Renström F; Rettig R; Rice KM; Roberts R; Rose LM; Rossouw J; Samani NJ; Sanna S; Saramies J; Schunkert H; Sebert S; Sheu WH-H; Shin Y-A; Sim X; Smit JH; Smith AV; Sosa MX; Spector TD; Stančáková A; Stanton A; Stirrups KE; Stringham HM; Sundstrom J; Swift AJ; Syvänen A-C; Tai E-S; Tanaka T; Tarasov KV; Teumer A; Thorsteinsdottir U; Tobin MD; Tremoli E; Uitterlinden AG; Uusitupa M; Vaez A; Vaidya D; van Duijn CM; van Iperen EPA; Vasan RS; Verwoert GC; Virtamo J; Vitart V; Voight BF; Vollenweider P; Wagner A; Wain LV; Wareham NJ; Watkins H; Weder AB; Westra H-J; Wilks R; Wilsgaard T; Wilson JF; Wong TY; Yang T-P; Yao J; Yengo L; Zhang W; Zhao JH; Zhu X; Bovet P; Cooper RS; Mohlke KL; Saleheen D; Lee J-Y; Elliott P; Gierman HJ; Willer CJ; Franke L; Hovingh GK; Taylor KD; Dedoussis G; Sever P; Wong A; Lind L; Assimes TL; Njølstad I; Schwarz PE; Langenberg C; Snieder H; Caulfield MJ; Melander O; Laakso M; Saltevo J; Rauramaa R; Tuomilehto J; Ingelsson E; Lehtimäki T; Hveem K; Palmas W; März W; Kumari M; Salomaa V; Chen Y-DI; Rotter JI; Froguel P; Jarvelin M-R; Lakatta EG; Kuulasmaa K; Franks PW; Hamsten A; Wichmann H-E; Palmer CNA; Stefansson K; Ridker PM; Loos RJF; Chakravarti A; Deloukas P; Morris AP; Newton-Cheh C; Munroe PB
Article: SCIENTIFIC REPORTS. 2016;6:31414

Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms.

Wågsäter D; Vorkapic E; van Stijn CMW; Kim J; Lusis AJ; Eriksson P; Tangirala RK
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2016;219:446-454

Perilipin 5 is protective in the ischemic heart.

Drevinge C; Dalen KT; Mannila MN; Täng MS; Ståhlman M; Klevstig M; Lundqvist A; Mardani I; Haugen F; Fogelstrand P; Adiels M; Asin-Cayuela J; Ekestam C; Gådin JR; Lee YK; Nebb H; Svedlund S; Johansson BR; Hultén LM; Romeo S; Redfors B; Omerovic E; Levin M; Gan L-M; Eriksson P; Andersson L; Ehrenborg E; Kimmel AR; Borén J; Levin MC
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2016;99(3):762-769

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections.

Guo D-C; Grove ML; Prakash SK; Eriksson P; Hostetler EM; LeMaire SA; Body SC; Shalhub S; Estrera AL; Safi HJ; Regalado ES; Zhou W; Mathis MR; GenTAC Investigators; BAVCon Investigators; Eagle KA; Yang B; Willer CJ; Boerwinkle E; Milewicz DM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(9):1947-1961

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

Perisic Matic L; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Röhl S; Kronqvist M; Aldi S; Magné J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojević V; Lehtiö J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: IJC HEART AND VASCULATURE. 2016;11:74-79

Intima-media thickness of the descending aorta in patients with bicuspid aortic valve.

Petrini J; Yousry M; Eriksson P; Björk HM; Rickenlund A; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: ATHEROSCLEROSIS. 2016;249:101-109

Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm.

Vorkapic E; Dugic E; Vikingsson S; Roy J; Mäyränpää MI; Eriksson P; Wågsäter D
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(5):e003031

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis.

Paramel Varghese G; Folkersen L; Strawbridge RJ; Halvorsen B; Yndestad A; Ranheim T; Krohg-Sørensen K; Skjelland M; Espevik T; Aukrust P; Lengquist M; Hedin U; Jansson J-H; Fransén K; Hansson GK; Eriksson P; Sirsjö A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):972-983

Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease.

Turner AW; Martinuk A; Silva A; Lau P; Nikpay M; Eriksson P; Folkersen L; Perisic L; Hedin U; Soubeyrand S; McPherson R
Article: THROMBOSIS AND HAEMOSTASIS. 2015;114(6):1165-1174

Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms.

Folkesson M; Li C; Frebelius S; Swedenborg J; Wågsäter D; Williams KJ; Eriksson P; Roy J; Liu M-L
Article: ELIFE. 2015;4:e08648

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome.

Doyle JJ; Doyle AJ; Wilson NK; Habashi JP; Bedja D; Whitworth RE; Lindsay ME; Schoenhoff F; Myers L; Huso N; Bachir S; Squires O; Rusholme B; Ehsan H; Huso D; Thomas CJ; Caulfield MJ; Van Eyk JE; Judge DP; Dietz HC; GenTAC Registry Consortium; MIBAVA Leducq Consortium
Article: PLOS GENETICS. 2015;11(9):e1005502

Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests.

Frånberg M; Gertow K; Hamsten A; PROCARDIS consortium; Lagergren J; Sennblad B
Article: ATHEROSCLEROSIS. 2015;241(2):561-568

TRIF adaptor signaling is important in abdominal aortic aneurysm formation.

Vorkapic E; Lundberg AM; Mäyränpää MI; Eriksson P; Wågsäter D
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2015;35(4):306-313

Aortic valve type and calcification as assessed by transthoracic and transoesophageal echocardiography.

Yousry M; Rickenlund A; Petrini J; Jenner J; Liska J; Eriksson P; Franco-Cereceda A; Eriksson MJ; Caidahl K
Article: BMC BIOINFORMATICS. 2015;16(1):194

AllelicImbalance: an R/bioconductor package for detecting, managing, and visualizing allele expression imbalance data from RNA sequencing.

Gådin JR; van't Hooft FM; Eriksson P; Folkersen L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(5):1226-1235

ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability.

Magné J; Gustafsson P; Jin H; Maegdefessel L; Hultenby K; Wernerson A; Eriksson P; Franco-Cereceda A; Kovanen PT; Gonçalves I; Ehrenborg E
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(suppl_1)

Abstract 267: CD93: A Novel Myocardial Infarction- Associated Protein with Glucose Regulatory Properties in Humans and Mice

Bäcklund A; Strawbridge R; Jin HJ; Tsikrika P; Silveira A; Ketelhuth DF; Eriksson P; Maegdefessel L; Hamsten A
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(suppl_1)

Abstract 261: Neutrophil Elastase Derived Fibrin Degradation Products are Increased in the Plasma of Patients with Abdominal Aortic Aneurysms and Correlate to the Intraluminal Thrombus Volume

Roy J; Silveira A; Liljeqvist Lindquist M; Folkesson M; Frebelius S; Hultgren R; Engstrom J; Swedenborg J; Eriksson P
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2015;372(17):1608-1618

Genetically determined height and coronary artery disease.

Nelson CP; Hamby SE; Saleheen D; Hopewell JC; Zeng L; Assimes TL; Kanoni S; Willenborg C; Burgess S; Amouyel P; Anand S; Blankenberg S; Boehm BO; Clarke RJ; Collins R; Dedoussis G; Farrall M; Franks PW; Groop L; Hall AS; Hamsten A; Hengstenberg C; Hovingh GK; Ingelsson E; Kathiresan S; Kee F; König IR; Kooner J; Lehtimäki T; März W; McPherson R; Metspalu A; Nieminen MS; O'Donnell CJ; Palmer CNA; Peters A; Perola M; Reilly MP; Ripatti S; Roberts R; Salomaa V; Shah SH; Schreiber S; Siegbahn A; Thorsteinsdottir U; Veronesi G; Wareham N; Willer CJ; Zalloua PA; Erdmann J; Deloukas P; Watkins H; Schunkert H; Danesh J; Thompson JR; Samani NJ; CARDIoGRAM+C4D Consortium
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;96(4):532-542

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.

Germain M; Chasman DI; de Haan H; Tang W; Lindström S; Weng L-C; de Andrade M; de Visser MCH; Wiggins KL; Suchon P; Saut N; Smadja DM; Le Gal G; van Hylckama Vlieg A; Di Narzo A; Hao K; Nelson CP; Rocanin-Arjo A; Folkersen L; Monajemi R; Rose LM; Brody JA; Slagboom E; Aïssi D; Gagnon F; Deleuze J-F; Deloukas P; Tzourio C; Dartigues J-F; Berr C; Taylor KD; Civelek M; Eriksson P; Cardiogenics Consortium; Psaty BM; Houwing-Duitermaat J; Goodall AH; Cambien F; Kraft P; Amouyel P; Samani NJ; Basu S; Ridker PM; Rosendaal FR; Kabrhel C; Folsom AR; Heit J; Reitsma PH; Trégouët D-A; Smith NL; Morange P-E
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(4):973-980

Aneurysm development in patients with a bicuspid aortic valve is not associated with transforming growth factor-β activation.

Paloschi V; Gådin JR; Khan S; Björck HM; Du L; Maleki S; Roy J; Lindeman JHM; Mohamed SA; Tsuda T; Franco-Cereceda A; Eriksson P
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2015;8(2):356-362

PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk.

Guardiola M; Exeter HJ; Perret C; Folkersen L; Van't Hooft F; Eriksson P; Franco-Cereceda A; Paulsson-Berne G; Palmen J; Li K; Cooper JA; Khaw K-T; Mallat Z; Ninio E; Karabina S-A; Humphries SE; Boekholdt SM; Holmes MV; Talmud PJ
Article: CIRCULATION RESEARCH. 2015;116(4):642-652

Increased arterial blood pressure and vascular remodeling in mice lacking salt-inducible kinase 1 (SIK1).

Bertorello AM; Pires N; Igreja B; Pinho MJ; Vorkapic E; Wågsäter D; Wikström J; Behrendt M; Hamsten A; Eriksson P; Soares-da-Silva P; Brion L
Article: NATURE. 2015;518(7538):187-196

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin D; Winkler TW; Croteau-Chonka DC; Ferreira T; Locke AE; Mägi R; Strawbridge RJ; Pers TH; Fischer K; Justice AE; Workalemahu T; Wu JMW; Buchkovich ML; Heard-Costa NL; Roman TS; Drong AW; Song C; Gustafsson S; Day FR; Esko T; Fall T; Kutalik Z; Luan J; Randall JC; Scherag A; Vedantam S; Wood AR; Chen J; Fehrmann R; Karjalainen J; Kahali B; Liu C-T; Schmidt EM; Absher D; Amin N; Anderson D; Beekman M; Bragg-Gresham JL; Buyske S; Demirkan A; Ehret GB; Feitosa MF; Goel A; Jackson AU; Johnson T; Kleber ME; Kristiansson K; Mangino M; Leach IM; Medina-Gomez C; Palmer CD; Pasko D; Pechlivanis S; Peters MJ; Prokopenko I; Stančáková A; Sung YJ; Tanaka T; Teumer A; Van Vliet-Ostaptchouk JV; Yengo L; Zhang W; Albrecht E; Ärnlöv J; Arscott GM; Bandinelli S; Barrett A; Bellis C; Bennett AJ; Berne C; Blüher M; Böhringer S; Bonnet F; Böttcher Y; Bruinenberg M; Carba DB; Caspersen IH; Clarke R; Daw EW; Deelen J; Deelman E; Delgado G; Doney AS; Eklund N; Erdos MR; Estrada K; Eury E; Friedrich N; Garcia ME; Giedraitis V; Gigante B; Go AS; Golay A; Grallert H; Grammer TB; Gräßler J; Grewal J; Groves CJ; Haller T; Hallmans G; Hartman CA; Hassinen M; Hayward C; Heikkilä K; Herzig K-H; Helmer Q; Hillege HL; Holmen O; Hunt SC; Isaacs A; Ittermann T; James AL; Johansson I; Juliusdottir T; Kalafati I-P; Kinnunen L; Koenig W; Kooner IK; Kratzer W; Lamina C; Leander K; Lee NR; Lichtner P; Lind L; Lindström J; Lobbens S; Lorentzon M; Mach F; Magnusson PK; Mahajan A; McArdle WL; Menni C; Merger S; Mihailov E; Milani L; Mills R; Moayyeri A; Monda KL; Mooijaart SP; Mühleisen TW; Mulas A; Müller G; Müller-Nurasyid M; Nagaraja R; Nalls MA; Narisu N; Glorioso N; Nolte IM; Olden M; Rayner NW; Renstrom F; Ried JS; Robertson NR; Rose LM; Sanna S; Scharnagl H; Scholtens S; Sennblad B; Seufferlein T; Sitlani CM; Smith AV; Stirrups K; Stringham HM; Sundström J; Swertz MA; Swift AJ; Syvänen A-C; Tayo BO; Thorand B; Thorleifsson G; Tomaschitz A; Troffa C; van Oort FV; Verweij N; Vonk JM; Waite LL; Wennauer R; Wilsgaard T; Wojczynski MK; Wong A; Zhang Q; Zhao JH; Brennan EP; Choi M; Eriksson P; Folkersen L; Franco-Cereceda A; Gharavi AG; Hedman ÅK; Hivert M-F; Huang J; Kanoni S; Karpe F; Keildson S; Kiryluk K; Liang L; Lifton RP; Ma B; McKnight AJ; McPherson R; Metspalu A; Min JL; Moffatt MF; Montgomery GW; Murabito JM; Nicholson G; Nyholt DR; Olsson C; Perry JR; Reinmaa E; Salem RM; Sandholm N; Schadt EE; Scott RA; Stolk L; Vallejo EE; Westra H-J; Zondervan KT; ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium; Amouyel P; Arveiler D; Bakker SJ; Beilby J; Bergman RN; Blangero J; Brown MJ; Burnier M; Campbell H; Chakravarti A; Chines PS; Claudi-Boehm S; Collins FS; Crawford DC; Danesh J; de Faire U; de Geus EJ; Dörr M; Erbel R; Eriksson JG; Farrall M; Ferrannini E; Ferrières J; Forouhi NG; Forrester T; Franco OH; Gansevoort RT; Gieger C; Gudnason V; Haiman CA; Harris TB; Hattersley AT; Heliövaara M; Hicks AA; Hingorani AD; Hoffmann W; Hofman A; Homuth G; Humphries SE; Hyppönen E; Illig T; Jarvelin M-R; Johansen B; Jousilahti P; Jula AM; Kaprio J; Kee F; Keinanen-Kiukaanniemi SM; Kooner JS; Kooperberg C; Kovacs P; Kraja AT; Kumari M; Kuulasmaa K; Kuusisto J; Lakka TA; Langenberg C; Le Marchand L; Lehtimäki T; Lyssenko V; Männistö S; Marette A; Matise TC; McKenzie CA; McKnight B; Musk AW; Möhlenkamp S; Morris AD; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Palmer LJ; Penninx BW; Peters A; Pramstaller PP; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ridker PM; Ritchie MD; Rudan I; Salomaa V; Samani NJ; Saramies J; Sarzynski MA; Schwarz PE; Shuldiner AR; Staessen JA; Steinthorsdottir V; Stolk RP; Strauch K; Tönjes A; Tremblay A; Tremoli E; Vohl M-C; Völker U; Vollenweider P; Wilson JF; Witteman JC; Adair LS; Bochud M; Boehm BO; Bornstein SR; Bouchard C; Cauchi S; Caulfield MJ; Chambers JC; Chasman DI; Cooper RS; Dedoussis G; Ferrucci L; Froguel P; Grabe H-J; Hamsten A; Hui J; Hveem K; Jöckel K-H; Kivimaki M; Kuh D; Laakso M; Liu Y; März W; Munroe PB; Njølstad I; Oostra BA; Palmer CN; Pedersen NL; Perola M; Pérusse L; Peters U; Power C; Quertermous T; Rauramaa R; Rivadeneira F; Saaristo TE; Saleheen D; Sinisalo J; Slagboom PE; Snieder H; Spector TD; Stefansson K; Stumvoll M; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Veronesi G; Walker M; Wareham NJ; Watkins H; Wichmann H-E; Abecasis GR; Assimes TL; Berndt SI; Boehnke M; Borecki IB; Deloukas P; Franke L; Frayling TM; Groop LC; Hunter DJ; Kaplan RC; O'Connell JR; Qi L; Schlessinger D; Strachan DP; Thorsteinsdottir U; van Duijn CM; Willer CJ; Visscher PM; Yang J; Hirschhorn JN; Zillikens MC; McCarthy MI; Speliotes EK; North KE; Fox CS; Barroso I; Franks PW; Ingelsson E; Heid IM; Loos RJ; Cupples LA; Morris AP; Lindgren CM; Mohlke KL
Article: NATURE. 2015;518(7538):197-206

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE; Kahali B; Berndt SI; Justice AE; Pers TH; Day FR; Powell C; Vedantam S; Buchkovich ML; Yang J; Croteau-Chonka DC; Esko T; Fall T; Ferreira T; Gustafsson S; Kutalik Z; Luan J; Mägi R; Randall JC; Winkler TW; Wood AR; Workalemahu T; Faul JD; Smith JA; Zhao JH; Zhao W; Chen J; Fehrmann R; Hedman ÅK; Karjalainen J; Schmidt EM; Absher D; Amin N; Anderson D; Beekman M; Bolton JL; Bragg-Gresham JL; Buyske S; Demirkan A; Deng G; Ehret GB; Feenstra B; Feitosa MF; Fischer K; Goel A; Gong J; Jackson AU; Kanoni S; Kleber ME; Kristiansson K; Lim U; Lotay V; Mangino M; Leach IM; Medina-Gomez C; Medland SE; Nalls MA; Palmer CD; Pasko D; Pechlivanis S; Peters MJ; Prokopenko I; Shungin D; Stančáková A; Strawbridge RJ; Sung YJ; Tanaka T; Teumer A; Trompet S; van der Laan SW; van Setten J; Van Vliet-Ostaptchouk JV; Wang Z; Yengo L; Zhang W; Isaacs A; Albrecht E; Ärnlöv J; Arscott GM; Attwood AP; Bandinelli S; Barrett A; Bas IN; Bellis C; Bennett AJ; Berne C; Blagieva R; Blüher M; Böhringer S; Bonnycastle LL; Böttcher Y; Boyd HA; Bruinenberg M; Caspersen IH; Chen Y-DI; Clarke R; Daw EW; de Craen AJM; Delgado G; Dimitriou M; Doney ASF; Eklund N; Estrada K; Eury E; Folkersen L; Fraser RM; Garcia ME; Geller F; Giedraitis V; Gigante B; Go AS; Golay A; Goodall AH; Gordon SD; Gorski M; Grabe H-J; Grallert H; Grammer TB; Gräßler J; Grönberg H; Groves CJ; Gusto G; Haessler J; Hall P; Haller T; Hallmans G; Hartman CA; Hassinen M; Hayward C; Heard-Costa NL; Helmer Q; Hengstenberg C; Holmen O; Hottenga J-J; James AL; Jeff JM; Johansson Å; Jolley J; Juliusdottir T; Kinnunen L; Koenig W; Koskenvuo M; Kratzer W; Laitinen J; Lamina C; Leander K; Lee NR; Lichtner P; Lind L; Lindström J; Lo KS; Lobbens S; Lorbeer R; Lu Y; Mach F; Magnusson PKE; Mahajan A; McArdle WL; McLachlan S; Menni C; Merger S; Mihailov E; Milani L; Moayyeri A; Monda KL; Morken MA; Mulas A; Müller G; Müller-Nurasyid M; Musk AW; Nagaraja R; Nöthen MM; Nolte IM; Pilz S; Rayner NW; Renstrom F; Rettig R; Ried JS; Ripke S; Robertson NR; Rose LM; Sanna S; Scharnagl H; Scholtens S; Schumacher FR; Scott WR; Seufferlein T; Shi J; Smith AV; Smolonska J; Stanton AV; Steinthorsdottir V; Stirrups K; Stringham HM; Sundström J; Swertz MA; Swift AJ; Syvänen A-C; Tan S-T; Tayo BO; Thorand B; Thorleifsson G; Tyrer JP; Uh H-W; Vandenput L; Verhulst FC; Vermeulen SH; Verweij N; Vonk JM; Waite LL; Warren HR; Waterworth D; Weedon MN; Wilkens LR; Willenborg C; Wilsgaard T; Wojczynski MK; Wong A; Wright AF; Zhang Q; LifeLines Cohort Study; Brennan EP; Choi M; Dastani Z; Drong AW; Eriksson P; Franco-Cereceda A; Gådin JR; Gharavi AG; Goddard ME; Handsaker RE; Huang J; Karpe F; Kathiresan S; Keildson S; Kiryluk K; Kubo M; Lee J-Y; Liang L; Lifton RP; Ma B; McCarroll SA; McKnight AJ; Min JL; Moffatt MF; Montgomery GW; Murabito JM; Nicholson G; Nyholt DR; Okada Y; Perry JRB; Dorajoo R; Reinmaa E; Salem RM; Sandholm N; Scott RA; Stolk L; Takahashi A; Tanaka T; van 't Hooft FM; Vinkhuyzen AAE; Westra H-J; Zheng W; Zondervan KT; ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium; Heath AC; Arveiler D; Bakker SJL; Beilby J; Bergman RN; Blangero J; Bovet P; Campbell H; Caulfield MJ; Cesana G; Chakravarti A; Chasman DI; Chines PS; Collins FS; Crawford DC; Cupples LA; Cusi D; Danesh J; de Faire U; den Ruijter HM; Dominiczak AF; Erbel R; Erdmann J; Eriksson JG; Farrall M; Felix SB; Ferrannini E; Ferrières J; Ford I; Forouhi NG; Forrester T; Franco OH; Gansevoort RT; Gejman PV; Gieger C; Gottesman O; Gudnason V; Gyllensten U; Hall AS; Harris TB; Hattersley AT; Hicks AA; Hindorff LA; Hingorani AD; Hofman A; Homuth G; Hovingh GK; Humphries SE; Hunt SC; Hyppönen E; Illig T; Jacobs KB; Jarvelin M-R; Jöckel K-H; Johansen B; Jousilahti P; Jukema JW; Jula AM; Kaprio J; Kastelein JJP; Keinanen-Kiukaanniemi SM; Kiemeney LA; Knekt P; Kooner JS; Kooperberg C; Kovacs P; Kraja AT; Kumari M; Kuusisto J; Lakka TA; Langenberg C; Marchand LL; Lehtimäki T; Lyssenko V; Männistö S; Marette A; Matise TC; McKenzie CA; McKnight B; Moll FL; Morris AD; Morris AP; Murray JC; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Madden PAF; Pasterkamp G; Peden JF; Peters A; Postma DS; Pramstaller PP; Price JF; Qi L; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ridker PM; Rioux JD; Ritchie MD; Rudan I; Salomaa V; Samani NJ; Saramies J; Sarzynski MA; Schunkert H; Schwarz PEH; Sever P; Shuldiner AR; Sinisalo J; Stolk RP; Strauch K; Tönjes A; Trégouët D-A; Tremblay A; Tremoli E; Virtamo J; Vohl M-C; Völker U; Waeber G; Willemsen G; Witteman JC; Zillikens MC; Adair LS; Amouyel P; Asselbergs FW; Assimes TL; Bochud M; Boehm BO; Boerwinkle E; Bornstein SR; Bottinger EP; Bouchard C; Cauchi S; Chambers JC; Chanock SJ; Cooper RS; de Bakker PIW; Dedoussis G; Ferrucci L; Franks PW; Froguel P; Groop LC; Haiman CA; Hamsten A; Hui J; Hunter DJ; Hveem K; Kaplan RC; Kivimaki M; Kuh D; Laakso M; Liu Y; Martin NG; März W; Melbye M; Metspalu A; Moebus S; Munroe PB; Njølstad I; Oostra BA; Palmer CNA; Pedersen NL; Perola M; Pérusse L; Peters U; Power C; Quertermous T; Rauramaa R; Rivadeneira F; Saaristo TE; Saleheen D; Sattar N; Schadt EE; Schlessinger D; Slagboom PE; Snieder H; Spector TD; Thorsteinsdottir U; Stumvoll M; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Weir DR; Wichmann H-E; Wilson JF; Zanen P; Borecki IB; Deloukas P; Fox CS; Heid IM; O'Connell JR; Strachan DP; Stefansson K; van Duijn CM; Abecasis GR; Franke L; Frayling TM; McCarthy MI; Visscher PM; Scherag A; Willer CJ; Boehnke M; Mohlke KL; Lindgren CM; Beckmann JS; Barroso I; North KE; Ingelsson E; Hirschhorn JN; Loos RJF; Speliotes EK
Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2014;148(6):2973-2980.e1

Ascending aortic dilatation is rarely associated with coronary artery disease regardless of aortic valve morphology.

Jackson V; Eriksson MJ; Caidahl K; Eriksson P; Franco-Cereceda A
Article: NATURE COMMUNICATIONS. 2014;5:5214

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.

Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nakagami F; Heymann HM; Chernogubova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(10):3081-3092

Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice.

Johansson ME; Zhang X-Y; Edfeldt K; Lundberg AM; Levin MC; Borén J; Li W; Yuan X-M; Folkersen L; Eriksson P; Hedin U; Low H; Sviridov D; Rios FJ; Hansson GK; Yan Z-Q
Article: AORTA. 2014;2(5):179-185

Differences in Elastin and Elastolytic Enzymes between Men and Women with Abdominal Aortic Aneurysm.

Villard C; Eriksson P; Swedenborg J; Hultgren R
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2014;3(4):e001040

Association between thoracic aortic disease and inguinal hernia.

Olsson C; Eriksson P; Franco-Cereceda A
Article: BMJ-BRITISH MEDICAL JOURNAL. 2014;349:g4164

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Holmes MV; Dale CE; Zuccolo L; Silverwood RJ; Guo Y; Ye Z; Prieto-Merino D; Dehghan A; Trompet S; Wong A; Cavadino A; Drogan D; Padmanabhan S; Li S; Yesupriya A; Leusink M; Sundstrom J; Hubacek JA; Pikhart H; Swerdlow DI; Panayiotou AG; Borinskaya SA; Finan C; Shah S; Kuchenbaecker KB; Shah T; Engmann J; Folkersen L; Eriksson P; Ricceri F; Melander O; Sacerdote C; Gamble DM; Rayaprolu S; Ross OA; McLachlan S; Vikhireva O; Sluijs I; Scott RA; Adamkova V; Flicker L; Bockxmeer FMV; Power C; Marques-Vidal P; Meade T; Marmot MG; Ferro JM; Paulos-Pinheiro S; Humphries SE; Talmud PJ; Mateo Leach I; Verweij N; Linneberg A; Skaaby T; Doevendans PA; Cramer MJ; van der Harst P; Klungel OH; Dowling NF; Dominiczak AF; Kumari M; Nicolaides AN; Weikert C; Boeing H; Ebrahim S; Gaunt TR; Price JF; Lannfelt L; Peasey A; Kubinova R; Pajak A; Malyutina S; Voevoda MI; Tamosiunas A; Maitland-van der Zee AH; Norman PE; Hankey GJ; Bergmann MM; Hofman A; Franco OH; Cooper J; Palmen J; Spiering W; de Jong PA; Kuh D; Hardy R; Uitterlinden AG; Ikram MA; Ford I; Hyppönen E; Almeida OP; Wareham NJ; Khaw K-T; Hamsten A; Husemoen LLN; Tjønneland A; Tolstrup JS; Rimm E; Beulens JWJ; Verschuren WMM; Onland-Moret NC; Hofker MH; Wannamethee SG; Whincup PH; Morris R; Vicente AM; Watkins H; Farrall M; Jukema JW; Meschia J; Cupples LA; Sharp SJ; Fornage M; Kooperberg C; LaCroix AZ; Dai JY; Lanktree MB; Siscovick DS; Jorgenson E; Spring B; Coresh J; Li YR; Buxbaum SG; Schreiner PJ; Ellison RC; Tsai MY; Patel SR; Redline S; Johnson AD; Hoogeveen RC; Hakonarson H; Rotter JI; Boerwinkle E; de Bakker PIW; Kivimaki M; Asselbergs FW; Sattar N; Lawlor DA; Whittaker J; Davey Smith G; Mukamal K; Psaty BM; Wilson JG; Lange LA; Hamidovic A; Hingorani AD; Nordestgaard BG; Bobak M; Leon DA; Langenberg C; Palmer TM; Reiner AP; Keating BJ; Dudbridge F; Casas JP; InterAct Consortium
Article: JOURNAL OF HEART VALVE DISEASE. 2014;23(4):463-472

Aortic dimensions in relation to bicuspid and tricuspid aortic valve pathology.

Jackson V; Petrini J; Eriksson MJ; Caidahl K; Eriksson P; Franco-Cereceda A
Article: ANNALS OF THORACIC SURGERY. 2014;98(1):65-71

Biomechanical properties of the thoracic aneurysmal wall: differences between bicuspid aortic valve and tricuspid aortic valve patients.

Forsell C; Björck HM; Eriksson P; Franco-Cereceda A; Gasser TC
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(24):8913-8918

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.

Mahdessian H; Taxiarchis A; Popov S; Silveira A; Franco-Cereceda A; Hamsten A; Eriksson P; van't Hooft F
Article: DIABETOLOGIA. 2014;57(6):1159-1172

A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness).

Strawbridge RJ; Deleskog A; McLeod O; Folkersen L; Kavousi M; Gertow K; Baldassarre D; Veglia F; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Dehghan A; Hofman A; Franco OH; Humphries SE; Tremoli E; de Faire U; Gustafsson S; Östensson C-G; Eriksson P; Öhrvik J; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2014;34(5):1093-1101

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Huang J; Huffman JE; Yamakuchi M; Trompet S; Asselbergs FW; Sabater-Lleal M; Trégouët D-A; Chen W-M; Smith NL; Kleber ME; Shin S-Y; Becker DM; Tang W; Dehghan A; Johnson AD; Truong V; Folkersen L; Yang Q; Oudot-Mellkah T; Buckley BM; Moore JH; Williams FMK; Campbell H; Silbernagel G; Vitart V; Rudan I; Tofler GH; Navis GJ; Destefano A; Wright AF; Chen M-H; de Craen AJM; Worrall BB; Rudnicka AR; Rumley A; Bookman EB; Psaty BM; Chen F; Keene KL; Franco OH; Böhm BO; Uitterlinden AG; Carter AM; Jukema JW; Sattar N; Bis JC; Ikram MA; Cohorts for Heart and Aging Research in Genome Epi; Sale MM; McKnight B; Fornage M; Ford I; Taylor K; Slagboom PE; McArdle WL; Hsu F-C; Franco-Cereceda A; Goodall AH; Yanek LR; Furie KL; Cushman M; Hofman A; Witteman JCM; Folsom AR; Basu S; Matijevic N; van Gilst WH; Wilson JF; Westendorp RGJ; Kathiresan S; Reilly MP; CARDIoGRAM Consortium; Tracy RP; Polasek O; Winkelmann BR; Grant PJ; Hillege HL; Cambien F; Stott DJ; Lowe GD; Spector TD; Meigs JB; Marz W; Eriksson P; Becker LC; Morange P-E; Soranzo N; Williams SM; Hayward C; van der Harst P; Hamsten A; Lowenstein CJ; Strachan DP; O'Donnell CJ; CHARGE Consortium Hemostatic Factor Working Group
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2014;7(2):144-150

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels.

Holmes MV; Exeter HJ; Folkersen L; Nelson CP; Guardiola M; Cooper JA; Sofat R; Boekholdt SM; Khaw K-T; Li K-W; Smith AJP; Van't Hooft F; Eriksson P; Franco-Cereceda A; Asselbergs FW; Boer JMA; Onland-Moret NC; Hofker M; Erdmann J; Kivimaki M; Kumari M; Reiner AP; Keating BJ; Humphries SE; Hingorani AD; Mallat Z; Samani NJ; Talmud PJ; CARDIoGRAM Consortium
Article: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY. 2014;27(4):393-404

Elastic properties of the descending aorta in patients with a bicuspid or tricuspid aortic valve and aortic valvular disease.

Petrini J; Jenner J; Rickenlund A; Eriksson P; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2014;24(2):124-131

Ceramides are associated with inflammatory processes in human mediastinal adipose tissue.

Gertow J; Kjellqvist S; Ståhlman M; Cheung L; Gottfries J; Werngren O; Borén J; Franco-Cereceda A; Eriksson P; Fisher RM
Article: PLOS ONE. 2014;9(8):e104082

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.

Sabater-Lleal M; Mälarstig A; Folkersen L; Soler Artigas M; Baldassarre D; Kavousi M; Almgren P; Veglia F; Brusselle G; Hofman A; Engström G; Franco OH; Melander O; Paulsson-Berne G; Watkins H; Eriksson P; Humphries SE; Tremoli E; de Faire U; Tobin MD; Hamsten A
Article: PLOS ONE. 2014;9(4):e95771

Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.

Popov S; Takemori H; Tokudome T; Mao Y; Otani K; Mochizuki N; Pires N; Pinho MJ; Franco-Cereceda A; Torielli L; Ferrandi M; Hamsten A; Soares-da-Silva P; Eriksson P; Bertorello AM; Brion L
Article: EUROPEAN HEART JOURNAL. 2013;34(48):3707-3716

Interleukin-6 receptor pathways in abdominal aortic aneurysm.

Harrison SC; Smith AJP; Jones GT; Swerdlow DI; Rampuri R; Bown MJ; Aneurysm Consortium; Folkersen L; Baas AF; de Borst GJ; Blankensteijn JD; Price JF; van der Graaf Y; McLachlan S; Agu O; Hofman A; Uitterlinden AG; Franco-Cereceda A; Ruigrok YM; van't Hof FN; Powell JT; van Rij AM; Casas JP; Eriksson P; Holmes MV; Asselbergs FW; Hingorani AD; Humphries SE
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2013;62(21):1966-1976

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

Holmes MV; Simon T; Exeter HJ; Folkersen L; Asselbergs FW; Guardiola M; Cooper JA; Palmen J; Hubacek JA; Carruthers KF; Horne BD; Brunisholz KD; Mega JL; van Iperen EPA; Li M; Leusink M; Trompet S; Verschuren JJW; Hovingh GK; Dehghan A; Nelson CP; Kotti S; Danchin N; Scholz M; Haase CL; Rothenbacher D; Swerdlow DI; Kuchenbaecker KB; Staines-Urias E; Goel A; van 't Hooft F; Gertow K; de Faire U; Panayiotou AG; Tremoli E; Baldassarre D; Veglia F; Holdt LM; Beutner F; Gansevoort RT; Navis GJ; Mateo Leach I; Breitling LP; Brenner H; Thiery J; Dallmeier D; Franco-Cereceda A; Boer JMA; Stephens JW; Hofker MH; Tedgui A; Hofman A; Uitterlinden AG; Adamkova V; Pitha J; Onland-Moret NC; Cramer MJ; Nathoe HM; Spiering W; Klungel OH; Kumari M; Whincup PH; Morrow DA; Braund PS; Hall AS; Olsson AG; Doevendans PA; Trip MD; Tobin MD; Hamsten A; Watkins H; Koenig W; Nicolaides AN; Teupser D; Day INM; Carlquist JF; Gaunt TR; Ford I; Sattar N; Tsimikas S; Schwartz GG; Lawlor DA; Morris RW; Sandhu MS; Poledne R; Maitland-van der Zee AH; Khaw K-T; Keating BJ; van der Harst P; Price JF; Mehta SR; Yusuf S; Witteman JCM; Franco OH; Jukema JW; de Knijff P; Tybjaerg-Hansen A; Rader DJ; Farrall M; Samani NJ; Kivimaki M; Fox KAA; Humphries SE; Anderson JL; Boekholdt SM; Palmer TM; Eriksson P; Paré G; Hingorani AD; Sabatine MS; Mallat Z; Casas JP; Talmud PJ
Article: MOLECULAR & CELLULAR PROTEOMICS. 2013;12(11):3398-3408

Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits.

Sharma A; Gulbahce N; Pevzner SJ; Menche J; Ladenvall C; Folkersen L; Eriksson P; Orho-Melander M; Barabási A-L
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;168(3):2264-2271

Valvular osteoclasts in calcification and aortic valve stenosis severity.

Nagy E; Eriksson P; Yousry M; Caidahl K; Ingelsson E; Hansson GK; Franco-Cereceda A; Bäck M
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2013;6(5):498-504

A variant in LDLR is associated with abdominal aortic aneurysm.

Bradley DT; Hughes AE; Badger SA; Jones GT; Harrison SC; Wright BJ; Bumpstead S; Baas AF; Grétarsdóttir S; Burnand K; Child AH; Clough RE; Cockerill G; Hafez H; Scott DJA; Ariëns RAS; Johnson A; Sohrabi S; Smith A; Thompson MM; van Bockxmeer FM; Waltham M; Matthíasson SE; Thorleifsson G; Thorsteinsdottir U; Blankensteijn JD; Teijink JAW; Wijmenga C; de Graaf J; Kiemeney LA; Wild JB; Edkins S; Gwilliam R; Hunt SE; Potter S; Lindholt JS; Golledge J; Norman PE; van Rij A; Powell JT; Eriksson P; Stefánsson K; Thompson JR; Humphries SE; Sayers RD; Deloukas P; Samani NJ; Bown MJ
Article: CIRCULATION. 2013;128(12):1310-1324

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Sabater-Lleal M; Huang J; Chasman D; Naitza S; Dehghan A; Johnson AD; Teumer A; Reiner AP; Folkersen L; Basu S; Rudnicka AR; Trompet S; Mälarstig A; Baumert J; Bis JC; Guo X; Hottenga JJ; Shin S-Y; Lopez LM; Lahti J; Tanaka T; Yanek LR; Oudot-Mellakh T; Wilson JF; Navarro P; Huffman JE; Zemunik T; Redline S; Mehra R; Pulanic D; Rudan I; Wright AF; Kolcic I; Polasek O; Wild SH; Campbell H; Curb JD; Wallace R; Liu S; Eaton CB; Becker DM; Becker LC; Bandinelli S; Räikkönen K; Widen E; Palotie A; Fornage M; Green D; Gross M; Davies G; Harris SE; Liewald DC; Starr JM; Williams FMK; Grant PJ; Spector TD; Strawbridge RJ; Silveira A; Sennblad B; Rivadeneira F; Uitterlinden AG; Franco OH; Hofman A; van Dongen J; Willemsen G; Boomsma DI; Yao J; Swords Jenny N; Haritunians T; McKnight B; Lumley T; Taylor KD; Rotter JI; Psaty BM; Peters A; Gieger C; Illig T; Grotevendt A; Homuth G; Völzke H; Kocher T; Goel A; Franzosi MG; Seedorf U; Clarke R; Steri M; Tarasov KV; Sanna S; Schlessinger D; Stott DJ; Sattar N; Buckley BM; Rumley A; Lowe GD; McArdle WL; Chen M-H; Tofler GH; Song J; Boerwinkle E; Folsom AR; Rose LM; Franco-Cereceda A; Teichert M; Ikram MA; Mosley TH; Bevan S; Dichgans M; Rothwell PM; Sudlow CLM; Hopewell JC; Chambers JC; Saleheen D; Kooner JS; Danesh J; Nelson CP; Erdmann J; Reilly MP; Kathiresan S; Schunkert H; Morange P-E; Ferrucci L; Eriksson JG; Jacobs D; Deary IJ; Soranzo N; Witteman JCM; de Geus EJC; Tracy RP; Hayward C; Koenig W; Cucca F; Jukema JW; Eriksson P; Seshadri S; Markus HS; Watkins H; Samani NJ; VTE Consortium; STROKE Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); C4D Consortium; CARDIoGRAM Consortium; Wallaschofski H; Smith NL; Tregouet D; Ridker PM; Tang W; Strachan DP; Hamsten A; O'Donnell CJ
Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2013;146(3):605-610

Aortic dimensions in patients with bicuspid and tricuspid aortic valves.

Jackson V; Olsson C; Eriksson P; Franco-Cereceda A
Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):p394

Array-based profiling reveals biomarker and therapeutic potential for different microRNAs in patients with symptomatic carotid stenosis

Eken SM; Osterholm C; Chernogubova E; Jin H; Razuvajev A; Perisic L; Hedin U; Roy J; Eriksson P; Maegdefessel L
Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):5937

MicroRNAs are novel plasma biomarkers for diagnosis and prognosis of abdominal aortic aneurysm disease

Eken SM; Chernogubova E; Jin H; Roy J; Hamsten A; Eriksson P; Tsao PS; Maegdefessel L
Article: JOURNAL OF VASCULAR SURGERY. 2013;58(2):333-339.e1

Mortality and reoperations in survivors operated on for acute type A aortic dissection and implications for catheter-based or hybrid interventions.

Olsson C; Hillebrant C-G; Liska J; Lockowandt U; Eriksson P; Franco-Cereceda A
Article: AORTA. 2013;1(1):13-22

Aneurysm Development in Patients With Bicuspid Aortic Valve (BAV): Possible Connection to Repair Deficiency?

Maleki S; Björck HM; Paloschi V; Kjellqvist S; Folkersen L; Jackson V; Franco-Cereceda A; Eriksson P
Article: NUTRITION & DIABETES. 2013;3(5):e66

Human mediastinal adipose tissue displays certain characteristics of brown fat.

Cheung L; Gertow J; Werngren O; Folkersen L; Petrovic N; Nedergaard J; Franco-Cereceda A; Eriksson P; Fisher RM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(5):1063-1069

Identification of a functional apolipoprotein E promoter polymorphism regulating plasma apolipoprotein E concentration.

Mannila MN; Mahdessian H; Franco-Cereceda A; Eggertsen G; de Faire U; Syvänen A-C; Eriksson P; Hamsten A; van 't Hooft FM
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2013;2(1):e000034

Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve.

Wågsäter D; Paloschi V; Hanemaaijer R; Hultenby K; Bank RA; Franco-Cereceda A; Lindeman JHN; Eriksson P
Article: ATHEROSCLEROSIS. 2013;226(2):440-446

A gene-centric study of common carotid artery remodelling.

Harrison SC; Zabaneh D; Asselbergs FW; Drenos F; Jones GT; Shah S; Gertow K; Sennblad B; Strawbridge RJ; Gigante B; Holewijn S; De Graaf J; Vermeulen S; Folkersen L; van Rij AM; Baldassarre D; Veglia F; Talmud PJ; Deanfield JE; Agu O; Kivimaki M; Kumari M; Bown MJ; Nyyssönen K; Rauramaa R; Smit AJ; Franco-Cereceda A; Giral P; Mannarino E; Silveira A; Syvänen A-C; de Borst GJ; van der Graaf Y; de Faire U; Baas AF; Blankensteijn JD; Wareham NJ; Fowkes G; Tzoulaki I; Price JF; Tremoli E; Hingorani AD; Eriksson P; Hamsten A; Humphries SE
Article: MOLECULAR & CELLULAR PROTEOMICS. 2013;12(2):407-425

A combined proteomic and transcriptomic approach shows diverging molecular mechanisms in thoracic aortic aneurysm development in patients with tricuspid- and bicuspid aortic valve.

Kjellqvist S; Maleki S; Olsson T; Chwastyniak M; Branca RMM; Lehtiö J; Pinet F; Franco-Cereceda A; Eriksson P
Article: PLOS ONE. 2013;8(11):e79473

Genetic variation in SULF2 is associated with postprandial clearance of triglyceride-rich remnant particles and triglyceride levels in healthy subjects.

Matikainen N; Burza MA; Romeo S; Hakkarainen A; Adiels M; Folkersen L; Eriksson P; Lundbom N; Ehrenborg E; Orho-Melander M; Taskinen M-R; Borén J
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2013;91(1):129-139

Identification of a novel flow-mediated gene expression signature in patients with bicuspid aortic valve.

Maleki S; Björck HM; Folkersen L; Nilsson R; Renner J; Caidahl K; Franco-Cereceda A; Länne T; Eriksson P
Journal article: NATURE GENETICS. 2013;45(1):25-U52

Large-scale association analysis identifies new risk loci for coronary artery disease

Deloukas P; Kanoni S; Willenborg C; Farrall M; Assimes TL; Thompson JR; Ingelsson E; Saleheen D; Erdmann J; Goldstein BA; Stirrups K; Koenig IR; Cazier J-B; Johansson A; Hall AS; Lee J-Y; Willer CJ; Chambers JC; Esko T; Folkersen L; Goel A; Grundberg E; Havulinna AS; Ho WK; Hopewell JC; Eriksson N; Kleber ME; Kristiansson K; Lundmark P; Lyytikainen L-P; Rafelt S; Shungin D; Strawbridge RJ; Thorleifsson G; Tikkanen E; Van Zuydam N; Voight BF; Waite LL; Zhang W; Ziegler A; Absher D; Altshuler D; Balmforth AJ; Barroso I; Braund PS; Burgdorf C; Claudi-Boehm S; Cox D; Dimitriou M; Do R; Doney ASF; El Mokhtari N; Eriksson P; Fischer K; Fontanillas P; Franco-Cereceda A; Gigante B; Groop L; Gustafsson S; Hager J; Hallmans G; Han B-G; Hunt SE; Kang HM; Illig T; Kessler T; Knowles JW; Kolovou G; Kuusisto J; Langenberg C; Langford C; Leander K; Lokki M-L; Lundmark A; McCarthy MI; Meisinger C; Melander O; Mihailov E; Maouche S; Morris AD; Mueller-Nurasyid M; Nikus K; Peden JF; Rayner NW; Rasheed A; Rosinger S; Rubin D; Rumpf MP; Schaefer A; Sivananthan M; Song C; Stewart AFR; Tan S-T; Thorgeirsson G; van der Schoot CE; Wagner PJ; Wells GA; Wild PS; Yang T-P; Amouyel P; Arveiler D; Basart H; Boehnke M; Boerwinkle E; Brambilla P; Cambien F; Cupples AL; de Faire U; Dehghan A; Diemert P; Epstein SE; Evans A; Ferrario MM; Ferrieres J; Gauguier D; Go AS; Goodall AH; Gudnason V; Hazen SL; Holm H; Iribarren C; Jang Y; Kahonen M; Kee F; Kim H-S; Klopp N; Koenig W; Kratzer W; Kuulasmaa K; Laakso M; Laaksonen R; Lee J-Y; Lind L; Ouwehand WH; Parish S; Park JE; Pedersen NL; Peters A; Quertermous T; Rader DJ; Salomaa V; Schadt E; Shah SH; Sinisalo J; Stark K; Stefansson K; Tregouet D-A; Virtamo J; Wallentin L; Wareham N; Zimmermann ME; Nieminen MS; Hengstenberg C; Sandhu MS; Pastinen T; Syvanen A-C; Hovingh GK; Dedoussis G; Franks PW; Lehtimaki T; Metspalu A; Zalloua PA; Siegbahn A; Schreiber S; Ripatti S; Blankenberg SS; Perola M; Clarke R; Boehm BO; O'Donnell C; Reilly MP; Maerz W; Collins R; Kathiresan S; Hamsten A; Kooner JS; Thorsteinsdottir U; Danesh J; Palmer CNA; Roberts R; Watkins H; Schunkert H; Samani NJ
Article: PLOS ONE. 2013;8(12):e83122

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.

Maubaret CG; Salpea KD; Romanoski CE; Folkersen L; Cooper JA; Stephanou C; Li KW; Palmen J; Hamsten A; Neil A; Stephens JW; Lusis AJ; Eriksson P; Talmud PJ; Humphries SE; Simon Broome Research Group; EARSII consortium
Article: NATURE GENETICS. 2013;45(1):25-33

Large-scale association analysis identifies new risk loci for coronary artery disease.

CARDIoGRAMplusC4D Consortium; Deloukas P; Kanoni S; Willenborg C; Farrall M; Assimes TL; Thompson JR; Ingelsson E; Saleheen D; Erdmann J; Goldstein BA; Stirrups K; König IR; Cazier J-B; Johansson A; Hall AS; Lee J-Y; Willer CJ; Chambers JC; Esko T; Folkersen L; Goel A; Grundberg E; Havulinna AS; Ho WK; Hopewell JC; Eriksson N; Kleber ME; Kristiansson K; Lundmark P; Lyytikäinen L-P; Rafelt S; Shungin D; Strawbridge RJ; Thorleifsson G; Tikkanen E; Van Zuydam N; Voight BF; Waite LL; Zhang W; Ziegler A; Absher D; Altshuler D; Balmforth AJ; Barroso I; Braund PS; Burgdorf C; Claudi-Boehm S; Cox D; Dimitriou M; Do R; DIAGRAM Consortium; CARDIOGENICS Consortium; Doney ASF; El Mokhtari N; Eriksson P; Fischer K; Fontanillas P; Franco-Cereceda A; Gigante B; Groop L; Gustafsson S; Hager J; Hallmans G; Han B-G; Hunt SE; Kang HM; Illig T; Kessler T; Knowles JW; Kolovou G; Kuusisto J; Langenberg C; Langford C; Leander K; Lokki M-L; Lundmark A; McCarthy MI; Meisinger C; Melander O; Mihailov E; Maouche S; Morris AD; Müller-Nurasyid M; MuTHER Consortium; Nikus K; Peden JF; Rayner NW; Rasheed A; Rosinger S; Rubin D; Rumpf MP; Schäfer A; Sivananthan M; Song C; Stewart AFR; Tan S-T; Thorgeirsson G; van der Schoot CE; Wagner PJ; Wellcome Trust Case Control Consortium; Wells GA; Wild PS; Yang T-P; Amouyel P; Arveiler D; Basart H; Boehnke M; Boerwinkle E; Brambilla P; Cambien F; Cupples AL; de Faire U; Dehghan A; Diemert P; Epstein SE; Evans A; Ferrario MM; Ferrières J; Gauguier D; Go AS; Goodall AH; Gudnason V; Hazen SL; Holm H; Iribarren C; Jang Y; Kähönen M; Kee F; Kim H-S; Klopp N; Koenig W; Kratzer W; Kuulasmaa K; Laakso M; Laaksonen R; Lee J-Y; Lind L; Ouwehand WH; Parish S; Park JE; Pedersen NL; Peters A; Quertermous T; Rader DJ; Salomaa V; Schadt E; Shah SH; Sinisalo J; Stark K; Stefansson K; Trégouët D-A; Virtamo J; Wallentin L; Wareham N; Zimmermann ME; Nieminen MS; Hengstenberg C; Sandhu MS; Pastinen T; Syvänen A-C; Hovingh GK; Dedoussis G; Franks PW; Lehtimäki T; Metspalu A; Zalloua PA; Siegbahn A; Schreiber S; Ripatti S; Blankenberg SS; Perola M; Clarke R; Boehm BO; O'Donnell C; Reilly MP; März W; Collins R; Kathiresan S; Hamsten A; Kooner JS; Thorsteinsdottir U; Danesh J; Palmer CNA; Roberts R; Watkins H; Schunkert H; Samani NJ
Article: BLOOD. 2012;120(24):4873-4881

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Huang J; Sabater-Lleal M; Asselbergs FW; Tregouet D; Shin S-Y; Ding J; Baumert J; Oudot-Mellakh T; Folkersen L; Johnson AD; Smith NL; Williams SM; Ikram MA; Kleber ME; Becker DM; Truong V; Mychaleckyj JC; Tang W; Yang Q; Sennblad B; Moore JH; Williams FMK; Dehghan A; Silbernagel G; Schrijvers EMC; Smith S; Karakas M; Tofler GH; Silveira A; Navis GJ; Lohman K; Chen M-H; Peters A; Goel A; Hopewell JC; Chambers JC; Saleheen D; Lundmark P; Psaty BM; Strawbridge RJ; Boehm BO; Carter AM; Meisinger C; Peden JF; Bis JC; McKnight B; Öhrvik J; Taylor K; Franzosi MG; Seedorf U; Collins R; Franco-Cereceda A; Syvänen A-C; Goodall AH; Yanek LR; Cushman M; Müller-Nurasyid M; Folsom AR; Basu S; Matijevic N; van Gilst WH; Kooner JS; Hofman A; Danesh J; Clarke R; Meigs JB; DIAGRAM Consortium; Kathiresan S; Reilly MP; CARDIoGRAM Consortium; Klopp N; Harris TB; Winkelmann BR; Grant PJ; Hillege HL; Watkins H; C4D Consortium; Spector TD; Becker LC; Tracy RP; März W; Uitterlinden AG; Eriksson P; Cambien F; CARDIOGENICS Consortium; Morange P-E; Koenig W; Soranzo N; van der Harst P; Liu Y; O'Donnell CJ; Hamsten A
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk.

Gertow K; Sennblad B; Strawbridge RJ; Ohrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimäki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikström M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssönen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvänen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):630-638

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.

Gaunt TR; Shah S; Nelson CP; Drenos F; Braund PS; Adeniran I; Folkersen L; Lawlor DA; Casas J-P; Amuzu A; Kivimaki M; Whittaker J; Eriksson P; Zhang H; Hancox JC; Tomaszewski M; Burton PR; Tobin MD; Humphries SE; Talmud PJ; Macfarlane PW; Hingorani AD; Samani NJ; Kumari M; Day INM
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2012;32(6):470-475

Real-time imaging required for optimal echocardiographic assessment of aortic valve calcification.

Yousry M; Rickenlund A; Petrini J; Gustavsson T; Prahl U; Liska J; Eriksson P; Franco-Cereceda A; Eriksson MJ; Caidahl K
Article: LIPIDS IN HEALTH AND DISEASE. 2012;11:115

Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue.

Kolak M; Gertow J; Westerbacka J; Summers SA; Liska J; Franco-Cereceda A; Orešič M; Yki-Järvinen H; Eriksson P; Fisher RM
Article: THROMBOSIS AND HAEMOSTASIS. 2012;108(3):485-492

Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue.

Ekström M; Liska J; Eriksson P; Sverremark-Ekström E; Tornvall P
Article: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2012;144(2):459-466

Matrix metalloproteinase 14 and 19 expression is associated with thoracic aortic aneurysms.

Jackson V; Olsson T; Kurtovic S; Folkersen L; Paloschi V; Wågsäter D; Franco-Cereceda A; Eriksson P
Article: GENDER MEDICINE. 2012;9(4):259-266.e2

Biomarkers for abdominal aortic aneurysms from a sex perspective.

Villard C; Wågsäter D; Swedenborg J; Eriksson P; Hultgren R
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2012;30(2):288-294

Serine protease inhibitor A3 in atherosclerosis and aneurysm disease.

Wågsäter D; Johansson D; Fontaine V; Vorkapic E; Bäcklund A; Razuvaev A; Mäyränpää MI; Hjerpe C; Caidahl K; Hamsten A; Franco-Cereceda A; Wilbertz J; Swedenborg J; Zhou X; Eriksson P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2012;32(8):2008-2016

A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time.

Sabater-Lleal M; Martinez-Perez A; Buil A; Folkersen L; Souto JC; Bruzelius M; Borrell M; Odeberg J; Silveira A; Eriksson P; Almasy L; Hamsten A; Soria JM
Article: DIABETES. 2012;61(8):2176-2186

Impact of common variation in bone-related genes on type 2 diabetes and related traits.

Billings LK; Hsu Y-H; Ackerman RJ; Dupuis J; Voight BF; Rasmussen-Torvik LJ; Hercberg S; Lathrop M; Barnes D; Langenberg C; Hui J; Fu M; Bouatia-Naji N; Lecoeur C; An P; Magnusson PK; Surakka I; Ripatti S; Christiansen L; Dalgård C; Folkersen L; Grundberg E; MAGIC Investigators; DIAGRAM + Consortium; MuTHER Consortium; ASCOT Investigators; GEFOS Consortium; Eriksson P; Kaprio J; Ohm Kyvik K; Pedersen NL; Borecki IB; Province MA; Balkau B; Froguel P; Shuldiner AR; Palmer LJ; Wareham N; Meneton P; Johnson T; Pankow JS; Karasik D; Meigs JB; Kiel DP; Florez JC
Article: ATHEROSCLEROSIS. 2012;223(1):223-229

Serum 25-hydroxyvitamin D concentration, established and emerging cardiovascular risk factors and risk of myocardial infarction before the age of 60 years.

Deleskog A; Piksasova O; Silveira A; Samnegård A; Tornvall P; Eriksson P; Gustafsson S; Ostenson C-G; Ohrvik J; Hamsten A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2012;303(1):H57-H65

Increases in intracellular sodium activate transcription and gene expression via the salt-inducible kinase 1 network in an atrial myocyte cell line.

Popov S; Venetsanou K; Chedrese PJ; Pinto V; Takemori H; Franco-Cereceda A; Eriksson P; Mochizuki N; Soares-da-Silva P; Bertorello AM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2012;32(6):1526-1534

Common and low-frequency genetic variants in the PCSK9 locus influence circulating PCSK9 levels.

Chernogubova E; Strawbridge R; Mahdessian H; Mälarstig A; Krapivner S; Gigante B; Hellénius M-L; de Faire U; Franco-Cereceda A; Syvänen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM
Article: MOLECULAR MEDICINE. 2012;18(1):712-718

A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis.

Krivospitskaya O; Elmabsout AA; Sundman E; Söderström LA; Ovchinnikova O; Gidlöf AC; Scherbak N; Norata GD; Samnegård A; Törmä H; Abdel-Halim SM; Jansson J-H; Eriksson P; Sirsjö A; Olofsson PS
Article: PLOS ONE. 2012;7(7):e41139

Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels.

Exeter HJ; Folkersen L; Palmen J; Franco-Cereceda A; Cooper JA; Kalea AZ; Hooft FV; Eriksson P; Humphries SE; Talmud PJ
Article: PLOS ONE. 2012;7(12):e52227

Characterization of shear-sensitive genes in the normal rat aorta identifies Hand2 as a major flow-responsive transcription factor.

Björck HM; Renner J; Maleki S; Nilsson SFE; Kihlberg J; Folkersen L; Karlsson M; Ebbers T; Eriksson P; Länne T
Article: PLOS GENETICS. 2012;8(8):e1002908

Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays.

Smith AJP; Howard P; Shah S; Eriksson P; Stender S; Giambartolomei C; Folkersen L; Tybjærg-Hansen A; Kumari M; Palmen J; Hingorani AD; Talmud PJ; Humphries SE
Article: PLOS ONE. 2012;7(6):e39574

The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues.

Pilbrow AP; Folkersen L; Pearson JF; Brown CM; McNoe L; Wang NM; Sweet WE; Tang WHW; Black MA; Troughton RW; Richards AM; Franco-Cereceda A; Gabrielsen A; Eriksson P; Moravec CS; Cameron VA
Article: PLOS ONE. 2012;7(2):e32306

Combined chromatin and expression analysis reveals specific regulatory mechanisms within cytokine genes in the macrophage early immune response.

Iglesias MJ; Reilly S-J; Emanuelsson O; Sennblad B; Pirmoradian Najafabadi M; Folkersen L; Mälarstig A; Lagergren J; Eriksson P; Hamsten A; Odeberg J
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2011;89(5):619-627

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.

Bown MJ; Jones GT; Harrison SC; Wright BJ; Bumpstead S; Baas AF; Gretarsdottir S; Badger SA; Bradley DT; Burnand K; Child AH; Clough RE; Cockerill G; Hafez H; Scott DJA; Futers S; Johnson A; Sohrabi S; Smith A; Thompson MM; van Bockxmeer FM; Waltham M; Matthiasson SE; Thorleifsson G; Thorsteinsdottir U; Blankensteijn JD; Teijink JAW; Wijmenga C; de Graaf J; Kiemeney LA; Assimes TL; McPherson R; CARDIoGRAM Consortium; Global BPgen Consortium; DIAGRAM Consortium; VRCNZ Consortium; Folkersen L; Franco-Cereceda A; Palmen J; Smith AJ; Sylvius N; Wild JB; Refstrup M; Edkins S; Gwilliam R; Hunt SE; Potter S; Lindholt JS; Frikke-Schmidt R; Tybjærg-Hansen A; Hughes AE; Golledge J; Norman PE; van Rij A; Powell JT; Eriksson P; Stefansson K; Thompson JR; Humphries SE; Sayers RD; Deloukas P; Samani NJ
Article: ANNALS OF THORACIC SURGERY. 2011;92(4):1376-1382

Mortality in acute type A aortic dissection: validation of the Penn classification.

Olsson C; Hillebrant C-G; Liska J; Lockowandt U; Eriksson P; Franco-Cereceda A
Article: ATHEROSCLEROSIS. 2011;218(2):294-299

Protease activity in the multi-layered intra-luminal thrombus of abdominal aortic aneurysms.

Folkesson M; Silveira A; Eriksson P; Swedenborg J
Article: DIABETES. 2011;60(10):2624-2634

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Strawbridge RJ; Dupuis J; Prokopenko I; Barker A; Ahlqvist E; Rybin D; Petrie JR; Travers ME; Bouatia-Naji N; Dimas AS; Nica A; Wheeler E; Chen H; Voight BF; Taneera J; Kanoni S; Peden JF; Turrini F; Gustafsson S; Zabena C; Almgren P; Barker DJP; Barnes D; Dennison EM; Eriksson JG; Eriksson P; Eury E; Folkersen L; Fox CS; Frayling TM; Goel A; Gu HF; Horikoshi M; Isomaa B; Jackson AU; Jameson KA; Kajantie E; Kerr-Conte J; Kuulasmaa T; Kuusisto J; Loos RJF; Luan J; Makrilakis K; Manning AK; Martínez-Larrad MT; Narisu N; Nastase Mannila M; Ohrvik J; Osmond C; Pascoe L; Payne F; Sayer AA; Sennblad B; Silveira A; Stancáková A; Stirrups K; Swift AJ; Syvänen A-C; Tuomi T; van 't Hooft FM; Walker M; Weedon MN; Xie W; Zethelius B; DIAGRAM Consortium; GIANT Consortium; MuTHER Consortium; CARDIoGRAM Consortium; C4D Consortium; Ongen H; Mälarstig A; Hopewell JC; Saleheen D; Chambers J; Parish S; Danesh J; Kooner J; Ostenson C-G; Lind L; Cooper CC; Serrano-Ríos M; Ferrannini E; Forsen TJ; Clarke R; Franzosi MG; Seedorf U; Watkins H; Froguel P; Johnson P; Deloukas P; Collins FS; Laakso M; Dermitzakis ET; Boehnke M; McCarthy MI; Wareham NJ; Groop L; Pattou F; Gloyn AL; Dedoussis GV; Lyssenko V; Meigs JB; Barroso I; Watanabe RM; Ingelsson E; Langenberg C; Hamsten A; Florez JC
Article: JOURNAL OF INTERNAL MEDICINE. 2011;270(3):229-236

Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.

Mälarstig A; Silveira A; Wågsäter D; Öhrvik J; Bäcklund A; Samnegård A; Khademi M; Hellenius M-L; Leander K; Olsson T; Uhlén M; de Faire U; Eriksson P; Hamsten A
Article: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 2011;40(3):e118-e124

Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: a study of 300 patients undergoing open-heart surgery.

Jackson V; Petrini J; Caidahl K; Eriksson MJ; Liska J; Eriksson P; Franco-Cereceda A
Article: INFLAMMATION. 2011;34(4):225-230

Effects of simvastatin on proinflammatory cytokines and matrix metalloproteinases in hypercholesterolemic individuals.

Nilsson L; Eriksson P; Cherfan P; Jonasson L
Article: JOURNAL OF VASCULAR SURGERY. 2011;54(2):341-345.e2

Reproductive history in women with abdominal aortic aneurysms.

Villard C; Swedenborg J; Eriksson P; Hultgren R
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2011;28(2):247-253

MMP-2 and MMP-9 are prominent matrix metalloproteinases during atherosclerosis development in the Ldlr(-/-)Apob(100/100) mouse.

Wågsäter D; Zhu C; Björkegren J; Skogsberg J; Eriksson P
Article: DIABETES. 2011;60(7):1894-1900

Comparison of dorsocervical with abdominal subcutaneous adipose tissue in patients with and without antiretroviral therapy-associated lipodystrophy.

Sevastianova K; Sutinen J; Greco D; Sievers M; Salmenkivi K; Perttilä J; Olkkonen VM; Wågsäter D; Lidell ME; Enerbäck S; Eriksson P; Walker UA; Auvinen P; Ristola M; Yki-Järvinen H
Article: AMERICAN JOURNAL OF HYPERTENSION. 2011;24(7):802-808

Gender-specific association of the plasminogen activator inhibitor-1 4G/5G polymorphism with central arterial blood pressure.

Björck HM; Eriksson P; Alehagen U; De Basso R; Ljungberg LU; Persson K; Dahlström U; Länne T
Article: CIRCULATION. 2011;123(12):1316-1325

Upregulation of the 5-lipoxygenase pathway in human aortic valves correlates with severity of stenosis and leads to leukotriene-induced effects on valvular myofibroblasts.

Nagy E; Andersson DC; Caidahl K; Eriksson MJ; Eriksson P; Franco-Cereceda A; Hansson GK; Bäck M
Article: PLOS ONE. 2011;6(3):e17652

A common polymorphism in the promoter region of the TNFSF4 gene is associated with lower allele-specific expression and risk of myocardial infarction.

Ria M; Lagercrantz J; Samnegård A; Boquist S; Hamsten A; Eriksson P
Article: NATURE GENETICS. 2011;43(4):339-U89

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

Coronary Artery Disease (C4D) Genetics Consortium
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2011;31(3):691-697

Impaired splicing of fibronectin is associated with thoracic aortic aneurysm formation in patients with bicuspid aortic valve.

Paloschi V; Kurtovic S; Folkersen L; Gomez D; Wågsäter D; Roy J; Petrini J; Eriksson MJ; Caidahl K; Hamsten A; Liska J; Michel J-B; Franco-Cereceda A; Eriksson P
Article: MOLECULAR MEDICINE. 2011;17(11-12):1365-1373

Unraveling divergent gene expression profiles in bicuspid and tricuspid aortic valve patients with thoracic aortic dilatation: the ASAP study.

Folkersen L; Wågsäter D; Paloschi V; Jackson V; Petrini J; Kurtovic S; Maleki S; Eriksson MJ; Caidahl K; Hamsten A; Michel J-B; Liska J; Gabrielsen A; Franco-Cereceda A; Eriksson P
Article: MOLECULAR MEDICINE. 2011;17(7-8):665-675

Diverging alternative splicing fingerprints in the transforming growth factor-β signaling pathway identified in thoracic aortic aneurysms.

Kurtovic S; Paloschi V; Folkersen L; Gottfries J; Franco-Cereceda A; Eriksson P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(49):21093-21097

Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm.

Di Gennaro A; Wågsäter D; Mäyränpää MI; Gabrielsen A; Swedenborg J; Hamsten A; Samuelsson B; Eriksson P; Haeggström JZ
Article: THROMBOSIS AND HAEMOSTASIS. 2010;104(5):998-1008

Allele-specific transcription of the PAI-1 gene in human astrocytes.

Hultman K; Tjarnlund-Wolf A; Odeberg J; Eriksson P; Jern C
Article: JOURNAL OF HEART VALVE DISEASE. 2010;19(6):724-730

Endothelin-1 and brain natriuretic peptide plasma levels decrease after aortic surgery.

Raffa GM; Jackson V; Liska J; Eriksson MJ; Caidahl K; Eriksson P; Franco-Cereceda A
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2010;59(9):1316-1318

Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids.

Olofsson LE; Olsson B; Lystig T; Jacobson P; Jernås M; Sjöholm K; Gummesson A; Sjöström L; Eriksson P; Hamsten A; Hale LP; Thelle DS; Carlsson B; Carlsson LMS
Article: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY. 2010;23(9):985-992

The feasibility of velocity vector imaging by transesophageal echocardiography for assessment of elastic properties of the descending aorta in aortic valve disease.

Petrini J; Yousry M; Rickenlund A; Liska J; Hamsten A; Eriksson P; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2010;3(4):365-373

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease.

Folkersen L; van't Hooft F; Chernogubova E; Agardh HE; Hansson GK; Hedin U; Liska J; Syvänen A-C; Paulsson-Berne G; Franco-Cereceda A; Hamsten A; Gabrielsen A; Eriksson P; BiKE and ASAP study groups
Article: JOURNAL OF INTERNAL MEDICINE. 2010;268(2):194-205

Low plasma adiponectin concentration is associated with myocardial infarction in young individuals.

Persson J; Lindberg K; Gustafsson TP; Eriksson P; Paulsson-Berne G; Lundman P
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2010;299(2):E234-E240

Systemic inflammation activates the nuclear factor-kappaB regulatory pathway in adipose tissue.

Ekström M; Halle M; Bjessmo S; Liska J; Kolak M; Fisher R; Eriksson P; Tornvall P
Article: NATURE GENETICS. 2010;42(8):692-697

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

Gretarsdottir S; Baas AF; Thorleifsson G; Holm H; den Heijer M; de Vries J-PPM; Kranendonk SE; Zeebregts CJAM; van Sterkenburg SM; Geelkerken RH; van Rij AM; Williams MJA; Boll APM; Kostic JP; Jonasdottir A; Jonasdottir A; Walters GB; Masson G; Sulem P; Saemundsdottir J; Mouy M; Magnusson KP; Tromp G; Elmore JR; Sakalihasan N; Limet R; Defraigne J-O; Ferrell RE; Ronkainen A; Ruigrok YM; Wijmenga C; Grobbee DE; Shah SH; Granger CB; Quyyumi AA; Vaccarino V; Patel RS; Zafari AM; Levey AI; Austin H; Girelli D; Pignatti PF; Olivieri O; Martinelli N; Malerba G; Trabetti E; Becker LC; Becker DM; Reilly MP; Rader DJ; Mueller T; Dieplinger B; Haltmayer M; Urbonavicius S; Lindblad B; Gottsäter A; Gaetani E; Pola R; Wells P; Rodger M; Forgie M; Langlois N; Corral J; Vicente V; Fontcuberta J; España F; Grarup N; Jørgensen T; Witte DR; Hansen T; Pedersen O; Aben KK; de Graaf J; Holewijn S; Folkersen L; Franco-Cereceda A; Eriksson P; Collier DA; Stefansson H; Steinthorsdottir V; Rafnar T; Valdimarsson EM; Magnadottir HB; Sveinbjornsdottir S; Olafsson I; Magnusson MK; Palmason R; Haraldsdottir V; Andersen K; Onundarson PT; Thorgeirsson G; Kiemeney LA; Powell JT; Carey DJ; Kuivaniemi H; Lindholt JS; Jones GT; Kong A; Blankensteijn JD; Matthiasson SE; Thorsteinsdottir U; Stefansson K
Article: JOURNAL OF LIPID RESEARCH. 2010;51(1):103-111

Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease.

Aminoff A; Ledmyr H; Thulin P; Lundell K; Nunez L; Strandhagen E; Murphy C; Lidberg U; Westerbacka J; Franco-Cereceda A; Liska J; Nielsen LB; Gåfvels M; Mannila MN; Hamsten A; Yki-Järvinen H; Thelle D; Eriksson P; Borén J; Ehrenborg E
Journal article: ARTERY RESEARCH. 2009;3(4):177-178

P2.03 The Plasminogen Activator Inhibitor-1 (4G/5G) Polymorphism Affects Central Arterial Blood Pressure in Women

Björck HM; Eriksson P; Alehagen U; Ljungberg LU; DeBasso R; Persson K; Dahlström U; Länne T
Article: PLOS ONE. 2009;4(11):e7677

Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.

Folkersen L; Kyriakou T; Goel A; Peden J; Mälarstig A; Paulsson-Berne G; Hamsten A; Hugh Watkins; Franco-Cereceda A; Gabrielsen A; Eriksson P; PROCARDIS consortia
Article: JOURNAL OF VASCULAR SURGERY. 2009;50(2):388-395

Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms.

Mäyränpää MI; Trosien JA; Fontaine V; Folkesson M; Kazi M; Eriksson P; Swedenborg J; Hedin U
Article: BIOINFORMATICS. 2009;25(15):1978-1979

GeneRegionScan: a Bioconductor package for probe-level analysis of specific, small regions of the genome.

Folkersen L; Diez D; Wheelock CE; Haeggström JZ; Goto S; Eriksson P; Gabrielsen A
Article: CIRCULATION JOURNAL. 2009;73(8):1531-1536

A functional interleukin-1 receptor antagonist polymorphism influences atherosclerosis development. The interleukin-1beta:interleukin-1 receptor antagonist balance in atherosclerosis.

Olofsson PS; Sheikine Y; Jatta K; Ghaderi M; Samnegård A; Eriksson P; Sirsjö A
Article: JOURNAL OF INFECTIOUS DISEASES. 2009;200(2):252-262

Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy.

Sievers M; Walker UA; Sevastianova K; Setzer B; Wågsäter D; Eriksson P; Yki-Järvinen H; Sutinen J
Journal article: [TITLE FIELD MISSING]. 2009;10(2):e417

Abstract: 1068 LOW ADIPONECTIN CONCENTRATION IS A RISK FACTOR FOR MYOCARDIAL INFARCTION AND LEVELS ARE INFLUENCED BY GENETIC VARIANTS

Persson J; Eriksson P; Gustafsson T; Berne GP; Lundman P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2009;87(4):337-346

Genetic variants of TNFSF4 and risk for carotid artery disease and stroke.

Olofsson PS; Söderström LA; Jern C; Sirsjö A; Ria M; Sundler E; de Faire U; Wiklund PG; Ohrvik J; Hedin U; Paulsson-Berne G; Hamsten A; Eriksson P; Hansson GK
Article: JOURNAL OF INTERNAL MEDICINE. 2009;265(3):373-381

Association of genetic variation on chromosome 9p21.3 and arterial stiffness.

Björck HM; Länne T; Alehagen U; Persson K; Rundkvist L; Hamsten A; Dahlström U; Eriksson P
Article: AMERICAN JOURNAL OF PATHOLOGY. 2009;174(2):693-700

T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice.

Ovchinnikova O; Robertson A-KL; Wågsäter D; Folco EJ; Hyry M; Myllyharju J; Eriksson P; Libby P; Hansson GK
Article: ATHEROSCLEROSIS. 2009;202(2):550-556

Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients.

Samnegård A; Hulthe J; Silveira A; Ericsson C-G; Hamsten A; Eriksson P
Article: ATHEROSCLEROSIS. 2009;202(2):415-423

Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression.

Wågsäter D; Zhu C; Björck HM; Eriksson P
Article: JOURNAL OF VIROLOGY. 2009;83(2):830-835

Infection with human cytomegalovirus alters the MMP-9/TIMP-1 balance in human macrophages.

Strååt K; de Klark R; Gredmark-Russ S; Eriksson P; Söderberg-Nauclér C
Article: SCANDINAVIAN CARDIOVASCULAR JOURNAL. 2008;42(5):327-336

Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9.

Chen F; Eriksson P; Whatling C; Vaage J; Valen G
Journal article: ARTERY RESEARCH. 2008;2(3):115-116

P2.38 The Anril Locus on Chromosome 9P21 Affects Stiffness of the Abdominal Aorta

Bjorck HM; Lanne T; Alehagen U; Persson K; Rundkvist L; Hamsten A; Dahlstrom U; Eriksson P
Article: HEART. 2008;94(6):724-729

Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome.

Mälarstig A; Eriksson P; Hamsten A; Lindahl B; Wallentin L; Siegbahn A
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2008;21(6):697-704

Expression profiling of macrophages from subjects with atherosclerosis to identify novel susceptibility genes.

Hägg DA; Jernås M; Wiklund O; Thelle DS; Fagerberg B; Eriksson P; Hamsten A; Olsson B; Carlsson B; Carlsson LMS; Svensson P-A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):975-982

Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction.

Mälarstig A; Sigurdsson S; Eriksson P; Paulsson-Berne G; Hedin U; Wallentin L; Siegbahn A; Hamsten A; Syvänen A-C
Article: JOURNAL OF INTERNAL MEDICINE. 2008;263(5):538-552

Identifying the susceptibility genes for coronary artery disease: from hyperbole through doubt to cautious optimism.

Hamsten A; Eriksson P
Article: CLINICAL CHEMISTRY. 2008;54(5):833-840

Genetic variants of tumor necrosis factor superfamily, member 4 (TNFSF4), and risk of incident atherothrombosis and venous thromboembolism.

Mälarstig A; Eriksson P; Rose L; Diehl KA; Hamsten A; Ridker PM; Zee RYL
Article: HUMAN MOLECULAR GENETICS. 2008;17(6):806-814

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p.

Broadbent HM; Peden JF; Lorkowski S; Goel A; Ongen H; Green F; Clarke R; Collins R; Franzosi MG; Tognoni G; Seedorf U; Rust S; Eriksson P; Hamsten A; Farrall M; Watkins H; PROCARDIS consortium
Article: ATHEROSCLEROSIS. 2008;196(2):514-522

ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques.

Wågsäter D; Björk H; Zhu C; Björkegren J; Valen G; Hamsten A; Eriksson P
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;151(2):317-325

Human T cells stimulate fibroblast-mediated degradation of extracellular matrix in vitro.

Mikko M; Fredriksson K; Wahlström J; Eriksson P; Grunewald J; Sköld CM
Article: PLOS COMPUTATIONAL BIOLOGY. 2008;4(1):e5

In silico detection of sequence variations modifying transcriptional regulation.

Andersen MC; Engström PG; Lithwick S; Arenillas D; Eriksson P; Lenhard B; Wasserman WW; Odeberg J
Article: TRANSLATIONAL RESEARCH. 2007;150(5):303-310

Effects of neurotrophins on human bronchial smooth muscle cell migration and matrix metalloproteinase-9 secretion.

Dagnell C; Kemi C; Klominek J; Eriksson P; Sköld CM; Eklund A; Grunewald J; Olgart Höglund C
Article: DIABETES. 2007;56(8):1960-1968

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.

Kolak M; Westerbacka J; Velagapudi VR; Wågsäter D; Yetukuri L; Makkonen J; Rissanen A; Häkkinen A-M; Lindell M; Bergholm R; Hamsten A; Eriksson P; Fisher RM; Oresic M; Yki-Järvinen H
Article: THROMBOSIS AND HAEMOSTASIS. 2007;98(2):427-433

Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms.

Folkesson M; Kazi M; Zhu C; Silveira A; Hemdahl A-L; Hamsten A; Hedin U; Swedenborg J; Eriksson P
Article: ATHEROSCLEROSIS. 2007;193(2):321-327

Post-prandial endothelial dysfunction in hypertriglyceridemic subjects: molecular mechanisms and gene expression studies.

Norata GD; Grigore L; Raselli S; Redaelli L; Hamsten A; Maggi F; Eriksson P; Catapano AL
Article: BLOOD COAGULATION & FIBRINOLYSIS. 2007;18(5):473-477

Coagulation factor VII and inflammatory markers in patients with coronary heart disease.

Ekström M; Silveira A; Bennermo M; Eriksson P; Tornvall P
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2007;102(6):2346-2351

A single bout of exercise activates matrix metalloproteinase in human skeletal muscle.

Rullman E; Rundqvist H; Wågsäter D; Fischer H; Eriksson P; Sundberg CJ; Jansson E; Gustafsson T
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2007;5(4):766-773

Elevated plasma fibrinogen gamma' concentration is associated with myocardial infarction: effects of variation in fibrinogen genes and environmental factors.

Mannila MN; Lovely RS; Kazmierczak SC; Eriksson P; Samnegård A; Farrell DH; Hamsten A; Silveira A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2007;92(2):720-724

Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes.

Kolak M; Yki-Järvinen H; Kannisto K; Tiikkainen M; Hamsten A; Eriksson P; Fisher RM
Article: JOURNAL OF INTERNAL MEDICINE. 2007;261(2):138-147

The association between fibrinogen haplotypes and myocardial infarction in men is partly mediated through pleiotropic effects on the serum IL-6 concentration.

Mannila MN; Eriksson P; Leander K; Wiman B; de Faire U; Hamsten A; Silveira A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;351(3):777-783

Allele-specific chromatin remodeling of the tumor necrosis factor-alpha promoter.

Skoog T; Hamsten A; Eriksson P
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2006;60(12):1406-1413

Fatty acid handling protein expression in adipose tissue, fatty acid composition of adipose tissue and serum, and markers of insulin resistance.

Gertow K; Rosell M; Sjögren P; Eriksson P; Vessby B; de Faire U; Hamsten A; Hellenius M-L; Fisher RM
Article: AMERICAN JOURNAL OF PATHOLOGY. 2006;169(6):2245-2253

Induction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-kappaB.

Bu D-X; Hemdahl A-L; Gabrielsen A; Fuxe J; Zhu C; Eriksson P; Yan Z-Q
Article: HUMAN REPRODUCTION. 2006;21(12):3146-3156

Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patients.

Pilka R; Oborna I; Lichnovsky V; Havelka P; Fingerova H; Eriksson P; Hansson S; Casslén B
Article: ATHEROSCLEROSIS. 2006;188(2):450-454

Plasma interleukin (IL)-18 concentrations is elevated in patients with previous myocardial infarction and related to severity of coronary atherosclerosis independently of C-reactive protein and IL-6.

Hulthe J; McPheat W; Samnegård A; Tornvall P; Hamsten A; Eriksson P
Article: ATHEROSCLEROSIS. 2006;188(2):462-466

Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease.

Sheikine Y; Bang CS; Nilsson L; Samnegård A; Hamsten A; Jonasson L; Eriksson P; Sirsjö A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(3):1150-1156

Allele-specific MMP-3 transcription under in vivo conditions.

Zhu C; Odeberg J; Hamsten A; Eriksson P
Journal article: VASCULAR PHARMACOLOGY. 2006;45(3):e145-e146

Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms

Folkesson M; Kazi M; Zhu C; Swedenborg J; Eriksson P; Hedin U; Hamsten A
Article: CLINICAL CHEMISTRY. 2006;52(8):1522-1527

Increased plasma concentration of matrix metalloproteinase-7 in patients with coronary artery disease.

Nilsson L; Jonasson L; Nijm J; Hamsten A; Eriksson P
Article: JOURNAL OF INTERNAL MEDICINE. 2006;259(5):530-536

Lower serum concentration of matrix metalloproteinase-3 in the acute stage of myocardial infarction.

Samnegård A; Silveira A; Tornvall P; Hamsten A; Ericsson C-G; Eriksson P
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2006;40(4):484-494

Triglyceride-rich lipoproteins from hypertriglyceridemic subjects induce a pro-inflammatory response in the endothelium: Molecular mechanisms and gene expression studies.

Norata GD; Grigore L; Raselli S; Seccomandi PM; Hamsten A; Maggi FM; Eriksson P; Catapano AL
Article: BMC MOLECULAR BIOLOGY. 2006;7:8

Alternative promoter usage of the membrane glycoprotein CD36.

Andersen M; Lenhard B; Whatling C; Eriksson P; Odeberg J
Article: THROMBOSIS AND HAEMOSTASIS. 2006;95(3):420-427

Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction.

Mannila MN; Eriksson P; Ericsson C-G; Hamsten A; Silveira A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;339(3):1001-1006

Human genetic evidence that OX40 is implicated in myocardial infarction.

Ria M; Eriksson P; Boquist S; Ericsson C-G; Hamsten A; Lagercrantz J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2006;26(1):136-142

Expression of neutrophil gelatinase-associated lipocalin in atherosclerosis and myocardial infarction.

Hemdahl A-L; Gabrielsen A; Zhu C; Eriksson P; Hedin U; Kastrup J; Thorén P; Hansson GK
Article: CIRCULATION RESEARCH. 2005;97(10):1070-1076

Haplotype effect of the matrix metalloproteinase-1 gene on risk of myocardial infarction.

Pearce E; Tregouet D-A; Samnegård A; Morgan AR; Cox C; Hamsten A; Eriksson P; Ye S
Article: JOURNAL OF INTERNAL MEDICINE. 2005;258(5):411-419

Serum matrix metalloproteinase-3 concentration is influenced by MMP-3 -1612 5A/6A promoter genotype and associated with myocardial infarction.

Samnegård A; Silveira A; Lundman P; Boquist S; Odeberg J; Hulthe J; McPheat W; Tornvall P; Bergstrand L; Ericsson C-G; Hamsten A; Eriksson P
Article: BRITISH JOURNAL OF SURGERY. 2005;92(11):1372-1376

Genotype-phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion.

Eriksson P; Jormsjö-Pettersson S; Brady AR; Deguchi H; Hamsten A; Powell JT
Article: OBESITY. 2005;13(10):1645-1650

A common beta2-adrenoceptor gene haplotype protects against obesity in Swedish women.

Jiao H; Dahlman I; Eriksson P; Kere J; Arner P
Article: STROKE. 2005;36(8):1661-1665

Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of stroke: replicated findings in two nested case-control studies based on independent cohorts.

Wiklund P-G; Nilsson L; Ardnor SN; Eriksson P; Johansson L; Stegmayr B; Hamsten A; Holmberg D; Asplund K
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(7):1341-1346

Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm.

Kazi M; Zhu C; Roy J; Paulsson-Berne G; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Article: CIRCULATION. 2005;111(21):2805-2811

High-density lipoproteins induce transforming growth factor-beta2 expression in endothelial cells.

Norata GD; Callegari E; Marchesi M; Chiesa G; Eriksson P; Catapano AL
Article: JOURNAL OF INTERNAL MEDICINE. 2005;257(5):415-422

Severity of coronary artery stenosis is associated with a polymorphism in the CXCL16/SR-PSOX gene.

Lundberg GA; Kellin A; Samnegård A; Lundman P; Tornvall P; Dimmeler S; Zeiher AM; Hamsten A; Hansson GK; Eriksson P
Article: NATURE GENETICS. 2005;37(5):486-494

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction.

Swanberg M; Lidman O; Padyukov L; Eriksson P; Akesson E; Jagodic M; Lobell A; Khademi M; Börjesson O; Lindgren CM; Lundman P; Brookes AJ; Kere J; Luthman H; Alfredsson L; Hillert J; Klareskog L; Hamsten A; Piehl F; Olsson T
Article: CORONARY ARTERY DISEASE. 2005;16(3):191-197

Apoptosis and angiogenesis are induced in the unstable coronary atherosclerotic plaque.

Chen F; Eriksson P; Kimura T; Herzfeld I; Valen G
Article: REGULATORY PEPTIDES. 2005;127(1-3):45-53

Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function.

Ding B; Kull B; Liu Z; Mottagui-Tabar S; Thonberg H; Gu HF; Brookes AJ; Grundemar L; Karlsson C; Hamsten A; Arner P; Ostenson C-G; Efendic S; Monné M; von Heijne G; Eriksson P; Wahlestedt C
Article: NATURE GENETICS. 2005;37(4):365-372

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.

Wang X; Ria M; Kelmenson PM; Eriksson P; Higgins DC; Samnegård A; Petros C; Rollins J; Bennet AM; Wiman B; de Faire U; Wennberg C; Olsson PG; Ishii N; Sugamura K; Hamsten A; Forsman-Semb K; Lagercrantz J; Paigen B
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(3):570-577

Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction.

Mannila MN; Eriksson P; Lundman P; Samnegård A; Boquist S; Ericsson C-G; Tornvall P; Hamsten A; Silveira A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(2):418-423

Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis.

Kyriakou T; Hodgkinson C; Pontefract DE; Iyengar S; Howell WM; Wong Y-K; Eriksson P; Ye S
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2005;15(1):57-65

Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque.

Chen F; Eriksson P; Hansson GK; Herzfeld I; Klein M; Hansson L-O; Valen G
Article: CESKA GYNEKOLOGIE. 2005;70(1):56-62

[MMP-26 mRNA and estrogen receptor alpha co-expression in normal and pathological endometrium].

Pilka R; Kudela M; Eriksson P; Casslén B
Journal article: PLOS COMPUTATIONAL BIOLOGY. 2005;preprint(2007):e5

In silico detection of sequence variations modifying transcriptional regulation

Andersen MC; Engström PG; Lithwick S; Arenillas D; Eriksson P; Lenhard B; Wasserman WW; Odeberg J
Article: THROMBOSIS AND HAEMOSTASIS. 2004;92(6):1240-1249

Plasma fibrinogen concentration predicts the risk of myocardial infarction differently in various parts of Europe: effects of beta-fibrinogen genotype and environmental factors. The HIFMECH Study.

Mannila MN; Silveira A; Hawe E; Eriksson P; Aillaud MF; Juhan-Vague I; Yudkin J; Margaglione M; di Minno G; Mussoni L; Tremoli E; Humphries S; Hamsten A; HIFMECH Study Group
Article: ATHEROSCLEROSIS. 2004;177(2):443-450

Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans.

Korstanje R; Eriksson P; Samnegård A; Olsson PG; Forsman-Semb K; Sen S; Churchill GA; Rollins J; Harris S; Hamsten A; Paigen B
Article: CESKA GYNEKOLOGIE. 2004;69(6):472-476

[Endometrial expression profiles of mRNA for selected matrix metalloproteinases and tissue inhibitor of metalloproteinases-1].

Pilka R; Kudela M; Eriksson P; Casslén B
Article: DIABETOLOGIA. 2004;47(11):1974-1979

alpha2-Heremans-Schmid glycoprotein gene polymorphisms are associated with adipocyte insulin action.

Dahlman I; Eriksson P; Kaaman M; Jiao H; Lindgren CM; Kere J; Arner P
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2004;127(1):97-104

Oxidised-HDL3 induces the expression of PAI-1 in human endothelial cells. Role of p38MAPK activation and mRNA stabilization.

Norata GD; Banfi C; Pirillo A; Tremoli E; Hamsten A; Catapano AL; Eriksson P
Article: GYNECOLOGIC ONCOLOGY. 2004;94(3):661-670

Matrix metalloproteinase-26 (matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancer.

Pilka R; Norata GD; Domanski H; Andersson C; Hansson S; Eriksson P; Casslén B
Article: MOLECULAR HUMAN REPRODUCTION. 2004;10(9):641-650

Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26.

Pilka R; Domanski H; Hansson S; Eriksson P; Casslén B
Article: JOURNAL OF LIPID RESEARCH. 2004;45(9):1768-1776

Effect of macrophage differentiation and exposure to mildly oxidized LDL on the proteolytic repertoire of THP-1 monocytes.

Whatling C; Björk H; Gredmark S; Hamsten A; Eriksson P
Article: EUROPEAN HEART JOURNAL. 2004;25(16):1447-1453

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction.

Edfeldt K; Bennet AM; Eriksson P; Frostegård J; Wiman B; Hamsten A; Hansson GK; de Faire U; Yan Z-Q
Article: STROKE. 2004;35(6):1310-1315

Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics.

Morgan AR; Rerkasem K; Gallagher PJ; Zhang B; Morris GE; Calder PC; Grimble RF; Eriksson P; McPheat WL; Shearman CP; Ye S
Article: DIABETOLOGIA. 2004;47(6):1118-1125

Expression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistance.

Gertow K; Pietiläinen KH; Yki-Järvinen H; Kaprio J; Rissanen A; Eriksson P; Hamsten A; Fisher RM
Journal article: CARDIOVASCULAR PATHOLOGY. 2004;13(3):96-97

INCREASED EXPRESSION OF NGAL IN ATHEROSCLEROSIS AND MYOCARDIAL INFARCTION

Hemdahl A-L; Gabrielsen A; Berne G; Eriksson P; Kastrup J; Steinbruchel D; Thorén P; Hansson GK
Journal article: CARDIOVASCULAR PATHOLOGY. 2004;13(3):17-18

INFLUENCE OF INTRALUMINAL THROMBUS ON STRUCTURAL FEATURES AND GENE EXPRESSION OF THE ANEURYSM WALL

Kazi M; Roy J; Björk H; Zhu C; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Journal article: CARDIOVASCULAR PATHOLOGY. 2004;13(3):29-30

HIGH-DENSITY LIPOPROTEIN SUBFRACTION 3 DECREASES ADAMTS-1 EXPRESSION INDUCED

Norata GD; Björk H; Hamsten A; Catapano AL; Eriksson P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(3):551-557

Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease.

Eriksson P; Deguchi H; Samnegård A; Lundman P; Boquist S; Tornvall P; Ericsson C-G; Bergstrand L; Hansson L-O; Ye S; Hamsten A
Article: INTERNATIONAL JOURNAL OF OBESITY. 2004;28(2):185-190

Relationship between beta-2 adrenoceptor gene haplotypes and adipocyte lipolysis in women.

Eriksson P; Dahlman I; Rydén M; Hoffstedt J; Arner P
Article: MATRIX BIOLOGY. 2004;22(7):557-560

High-density lipoprotein subfraction 3 decreases ADAMTS-1 expression induced by lipopolysaccharide and tumor necrosis factor-alpha in human endothelial cells.

Norata GD; Björk H; Hamsten A; Catapano AL; Eriksson P
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2004;89(1):392-399

Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome.

Gertow K; Bellanda M; Eriksson P; Boquist S; Hamsten A; Sunnerhagen M; Fisher RM
Article: BLOOD COAGULATION & FIBRINOLYSIS. 2003;14(8):749-753

No evidence that the PLA1/PLA2 polymorphism of platelet glycoprotein IIIa is implicated in angiographically characterized coronary atherosclerosis and premature myocardial infarction.

Lagercrantz J; Bergman M; Lundman P; Tornvall P; Hjemdahl P; Hamsten A; Eriksson P
Article: CARDIOVASCULAR RESEARCH. 2003;59(1):169-180

Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL.

Norata GD; Pirillo A; Callegari E; Hamsten A; Catapano AL; Eriksson P
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2003;12(1):73-78

Effects of HDL3 on the expression of matrix-degrading proteases in human endothelial cells.

Norata GD; Pellegatta F; Hamsten A; Catapano AL; Eriksson P
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2003;41(12):2130-2137

Influences of matrix metalloproteinase-3 gene variation on extent of coronary atherosclerosis and risk of myocardial infarction.

Beyzade S; Zhang S; Wong Y-K; Day INM; Eriksson P; Ye S
Article: MOLECULAR HUMAN REPRODUCTION. 2003;9(5):271-277

Epithelial expression of matrix metalloproteinase-26 is elevated at mid-cycle in the human endometrium.

Pilka R; Whatling C; Domanski H; Hansson S; Eriksson P; Casslén B
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(4):637-643

Evidence that peroxisome proliferator-activated receptor delta influences cholesterol metabolism in men.

Skogsberg J; Kannisto K; Cassel TN; Hamsten A; Eriksson P; Ehrenborg E
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(4):688-694

Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy.

Yki-Järvinen H; Sutinen J; Silveira A; Korsheninnikova E; Fisher RM; Kannisto K; Ehrenborg E; Eriksson P; Hamsten A
Article: ATHEROSCLEROSIS. 2003;167(2):265-273

A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution.

Gertow K; Skoglund-Andersson C; Eriksson P; Boquist S; Orth-Gomér K; Schenck-Gustafsson K; Hamsten A; Fisher RM
Article: HORMONE AND METABOLIC RESEARCH. 2002;34(11-12):698-702

Glucocorticoid-regulated adipose tissue secretion of PAI-1, but not IL-6, TNFalpha or leptin in vivo.

Uddén J; Eriksson P; Hoffstedt J
Article: BIOTECHNIQUES. 2002;33(5):1104-1108

Molecular haplotyping by pyrosequencing.

Odeberg J; Holmberg K; Eriksson P; Uhlén M
Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(3):939-945

Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice.

Jormsjö S; Wuttge DM; Sirsjö A; Whatling C; Hamsten A; Stemme S; Eriksson P
Article: HORMONE AND METABOLIC RESEARCH. 2002;34(7):355-359

A polymorphism in the leptin promoter region (-2548 G/A) influences gene expression and adipose tissue secretion of leptin.

Hoffstedt J; Eriksson P; Mottagui-Tabar S; Arner P
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2002;23(5):421-425

The influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysm.

Jones K; Powell J; Brown L; Greenhalgh R; Jormsjö S; Eriksson P
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2002;51(3):327-333

Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-kappaB activation.

Dichtl W; Ares MPS; Jönson AN; Jovinge S; Pachinger O; Giachelli CM; Hamsten A; Eriksson P; Nilsson J
Article: EUROPEAN HEART JOURNAL. 2002;23(5):376-383

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men.

Skoog T; Dichtl W; Boquist S; Skoglund-Andersson C; Karpe F; Tang R; Bond MG; de Faire U; Nilsson J; Eriksson P; Hamsten A
Article: INTERNATIONAL JOURNAL OF OBESITY. 2001;25(11):1599-1603

The Arg 389 Gly beta1-adrenergic receptor gene polymorphism and human fat cell lipolysis.

Rydén M; Hoffstedt J; Eriksson P; Bringman S; Arner P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2001;21(11):1834-1839

Allele-specific regulation of matrix metalloproteinase-7 promoter activity is associated with coronary artery luminal dimensions among hypercholesterolemic patients.

Jormsjö S; Whatling C; Walter DH; Zeiher AM; Hamsten A; Eriksson P
Article: DIABETOLOGIA. 2001;44(10):1268-1273

Fatty acid binding protein expression in different adipose tissue depots from lean and obese individuals.

Fisher RM; Eriksson P; Hoffstedt J; Hotamisligil GS; Thörne A; Rydén M; Hamsten A; Arner P
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;159(2):417-423

Expression of interleukin-15 in mouse and human atherosclerotic lesions.

Wuttge DM; Eriksson P; Sirsjö A; Hansson GK; Stemme S
Article: DIABETES. 2001;50(7):1522-1530

Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: insights into the signaling pathway.

Banfi C; Eriksson P; Giandomenico G; Mussoni L; Sironi L; Hamsten A; Tremoli E
Article: MOLECULAR MEDICINE. 2001;7(6):383-392

Gene expression in atherosclerotic lesion of ApoE deficient mice.

Wuttge DM; Sirsjö A; Eriksson P; Stemme S
Article: ATHEROSCLEROSIS. 2001;154(3):703-711

Polymorphisms in the thrombopoietin gene are associated with risk of myocardial infarction at a young age.

Webb KE; Martin JF; Hamsten A; Eriksson P; Iacoviello L; Gattone M; Donati MB; Di Castelnuovo A; Erusalimsky J; Humphries SE
Article: THROMBOSIS AND HAEMOSTASIS. 2000;84(4):706-711

In vivo stimulation of vascular plasminogen activator inhibitor-1 production by very low-density lipoprotein involves transcription factor binding to a VLDL-responsive element.

Dichtl W; Ares MP; Stollenwerk M; Giachelli CM; Scatena M; Hamsten A; Eriksson P; Nilsson J
Journal article: ATHEROSCLEROSIS. 2000;151(1):79

Fatty acid binding proteins in different human adipose tissue depots: Relationships to serum insulin concentrations

Fisher RM; Eriksson P; Hoffstedt J; Hamsten A; Arner P
Journal article: ATHEROSCLEROSIS. 2000;151(1):159

Genetic regulation of the MMP-7 and MMP-12 gene expression

Jormsjö S; Ye S; Moritz J; Burt B; Henney A; Hamsten A; Eriksson P
Article: JOURNAL OF INTERNAL MEDICINE. 2000;247(6):651-656

The Q/E27 polymorphism in the beta2-adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins.

Ehrenborg E; Skogsberg J; Ruotolo G; Large V; Eriksson P; Arner P; Hamsten A
Article: CIRCULATION RESEARCH. 2000;86(9):998-1003

Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease.

Jormsjö S; Ye S; Moritz J; Walter DH; Dimmeler S; Zeiher AM; Henney A; Hamsten A; Eriksson P
Article: THROMBOSIS AND HAEMOSTASIS. 2000;83(4):545-548

Regional variation in plasminogen activator inhibitor-1 expression in adipose tissue from obese individuals.

Eriksson P; Van Harmelen V; Hoffstedt J; Lundquist P; Vidal H; Stemme V; Hamsten A; Arner P; Reynisdottir S
Article: THROMBOSIS AND HAEMOSTASIS. 2000;83(2):304-308

Role of gender and genetic variance in plasminogen activator inhibitor-1 secretion from human adipose tissue.

van Harmelen V; Wahrenberg H; Eriksson P; Arner P
Article: DIABETOLOGIA. 2000;43(1):117-120

Excessive fat accumulation is associated with the TNF alpha-308 G/A promoter polymorphism in women but not in men.

Hoffstedt J; Eriksson P; Hellström L; Rössner S; Rydén M; Arner P
Article: FREE RADICAL RESEARCH. 1999;31(6):503-512

Hydrogen peroxide induces mRNA for tumour necrosis factor alpha in human endothelial cells.

Valen G; Erl W; Eriksson P; Wuttge D; Paulsson G; Hansson GK
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(12):3063-3070

Two common, functional polymorphisms in the promoter region of the beta-fibrinogen gene contribute to regulation of plasma fibrinogen concentration.

van 't Hooft FM; von Bahr SJ; Silveira A; Iliadou A; Eriksson P; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(12):3025-3032

Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells.

Dichtl W; Stiko A; Eriksson P; Goncalves I; Calara F; Banfi C; Ares MP; Hamsten A; Nilsson J
Article: HUMAN GENETICS. 1999;105(5):418-423

Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1.

Zhang B; Henney A; Eriksson P; Hamsten A; Watkins H; Ye S
Article: JOURNAL OF LIPID RESEARCH. 1999;40(9):1686-1694

A functional polymorphism in the apolipoprotein B promoter that influences the level of plasma low density lipoprotein.

van 't Hooft FM; Jormsjö S; Lundahl B; Tornvall P; Eriksson P; Hamsten A
Article: HUMAN MOLECULAR GENETICS. 1999;8(8):1443-1449

A common functional polymorphism (C-->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha.

Skoog T; van't Hooft FM; Kallin B; Jovinge S; Boquist S; Nilsson J; Eriksson P; Hamsten A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(6):1577-1581

Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.

Nilsson L; Takemura T; Eriksson P; Hamsten A
Article: BLOOD. 1999;93(10):3432-3441

Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration.

van 't Hooft FM; Silveira A; Tornvall P; Iliadou A; Ehrenborg E; Eriksson P; Hamsten A
Article: CIRCULATION RESEARCH. 1999;84(9):1085-1094

Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells.

Dichtl W; Nilsson L; Goncalves I; Ares MP; Banfi C; Calara F; Hamsten A; Eriksson P; Nilsson J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(5):1354-1360

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells.

Allison BA; Nilsson L; Karpe F; Hamsten A; Eriksson P
Article: JOURNAL OF LIPID RESEARCH. 1999;40(5):913-919

VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor.

Nilsson L; Gåfvels M; Musakka L; Ensler K; Strickland DK; Angelin B; Hamsten A; Eriksson P
Article: CIRCULATION. 1999;99(14):1788-1794

Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis.

Zhang B; Ye S; Herrmann SM; Eriksson P; de Maat M; Evans A; Arveiler D; Luc G; Cambien F; Hamsten A; Watkins H; Henney AM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(11):1679-1685

Unsaturated fatty acids increase plasminogen activator inhibitor-1 expression in endothelial cells.

Nilsson L; Banfi C; Diczfalusy U; Tremoli E; Hamsten A; Eriksson P
Article: DIABETES. 1998;47(6):913-917

Leptin secretion from subcutaneous and visceral adipose tissue in women.

Van Harmelen V; Reynisdottir S; Eriksson P; Thörne A; Hoffstedt J; Lönnqvist F; Arner P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(5):756-761

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.

Karpe F; Lundahl B; Ehrenborg E; Eriksson P; Hamsten A
Journal article: GROWTH HORMONE & IGF RESEARCH. 1998;8:201

Growth hormone and insulin-like growth factor I improve cardiac function and regulate expression of the Fas receptor in rats after experimental myocardial infarction

Tivesten Å; Matejka G; Caidahl K; Kujacic V; Eriksson P; Sun XY; Brantsing C; Hedner T; Bengtsson B-Å; Isgaard J
Article: DIABETOLOGIA. 1998;41(1):65-71

Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals.

Eriksson P; Reynisdottir S; Lönnqvist F; Stemme V; Hamsten A; Arner P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(1):20-26

Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia.

Eriksson P; Nilsson L; Karpe F; Hamsten A
Article: JOURNAL OF CLINICAL INVESTIGATION. 1997;100(12):3005-3013

Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function.

Large V; Hellström L; Reynisdottir S; Lönnqvist F; Eriksson P; Lannfelt L; Arner P
Journal article: FIBRINOLYSIS AND PROTEOLYSIS. 1997;11:28

97 Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals

Eriksson P; Reynisdottir S; Lönnqvist F; Stemme V; Hamsten A; Arner P
Article: MOLECULAR HUMAN REPRODUCTION. 1997;3(9):781-787

Differential regulation of the plasminogen activator inhibitor-1 (PAI-1) gene expression by growth factors and progesterone in human endometrial stromal cells.

Sandberg T; Eriksson P; Gustavsson B; Casslén B
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(22):13055-13060

Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression.

Ye S; Eriksson P; Hamsten A; Kurkinen M; Humphries SE; Henney AM
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1995;15(10):1584-1590

Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-kappa B in human vascular smooth muscle cells.

Ares MP; Kallin B; Eriksson P; Nilsson J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1995;15(5):655-664

Coagulation factor VII mass and activity in young men with myocardial infarction at a young age. Role of plasma lipoproteins and factor VII genotype.

Moor E; Silveira A; van't Hooft F; Suontaka AM; Eriksson P; Blombäck M; Hamsten A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(6):1851-1855

Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction.

Eriksson P; Kallin B; van 't Hooft FM; Båvenholm P; Hamsten A
Journal article: CURRENT OPINION IN LIPIDOLOGY. 1994;5(5):382-389

Relationships of thrombosis and fibrinolysis to atherosclerosis.

Hamsten A; Eriksson P; Karpe F; Silveira A
Journal article: FIBRINOLYSIS. 1994;8:253-262

FIBRINOLYSIS AND ATHEROSCLEROSIS - AN UPDATE

HAMSTEN A; ERIKSSON P
Journal article: FIBRINOLYSIS AND PROTEOLYSIS. 1994;8:79

Functional studies of an 4G/5G polymorphism in the PAI-1 promoter region which is associated with myocardial infarction at a young age

Eriksson P; Kallin B; van 't Hooft F; Hamsten A
Journal article: FEBS JOURNAL. 1993;215(2):505-511

The glucocorticoid receptor acts as an antirepressor in receptor-dependent in vitro transcription.

Eriksson P; Wrange O
Journal article: JOURNAL OF STRUCTURAL BIOLOGY. 1991;107(1):48-55

The glucocorticoid receptor in homodimeric and monomeric form visualised by electron microscopy.

Eriksson P; Daneholt B; Wrange O
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1990;265(28):17222-17229

Quantitative analysis of the glucocorticoid receptor-DNA interaction at the mouse mammary tumor virus glucocorticoid response element.

Perlmann T; Eriksson P; Wrange O
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1990;265(6):3535-3542

Protein-protein contacts in the glucocorticoid receptor homodimer influence its DNA binding properties.

Eriksson P; Wrange O
Journal article: MOLECULAR AND CELLULAR BIOLOGY. 1989;9(12):5305-5314

Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription.

Drouin J; Trifiro MA; Plante RK; Nemer M; Eriksson P; Wrange O
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1989;264(9):5253-5259

The purified activated glucocorticoid receptor is a homodimer.

Wrange O; Eriksson P; Perlmann T
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Preprint: MEDRXIV. 2024;MEDRXIV

A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes.

Saliba-Gustafsson P; Justesen JM; Ranta A; Sharma D; Bielczyk-Maczynska E; Li J; Najmi LA; Apodaka M; Aspichueta P; Björck HM; Eriksson P; Franco-Cereceda A; Gloudemans M; Mujica E; den Hoed M; Assimes TL; Quertermous T; Carcamo-Orive I; Park CY; Knowles JW
Conference publication: ATHEROSCLEROSIS. 2023;379:s5

FOXC1 CONTROLS SMOOTH MUSCLE CELL ACTIVATION IN VASCULAR DISEASE

Matic L; Rykaczewska U; Suur B; Gaelle A; Quanyi Z; Xiang Z; Narayanan S; Hedman A; Lengquist M; Kronqvist M; Vuckovic S; Sward K; Razuvaev A; Malarstig A; Eriksson P; Miller C; Quertermous T; Hedin U
Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:s756-s757

Statins regulate PNPLA3 through a mechanism that requires SREBF2 in human liver cells

Ahmed O; Shavva VS; Dai W; Tarnawski L; Malin S; Franco-Cereceda A; Eriksson P; Bjorck H; Olofsson P
Preprint: MEDRXIV. 2021;MEDRXIV

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.

Klaric L; Gisby JS; Papadaki A; Muckian MD; Macdonald-Dunlop E; Zhao JH; Tokolyi A; Persyn E; Pairo-Castineira E; Morris AP; Kalnapenkis A; Richmond A; Landini A; Hedman ÅK; Prins B; Zanetti D; Wheeler E; Kooperberg C; Yao C; Petrie JR; Fu J; Folkersen L; Walker M; Magnusson M; Eriksson N; Mattsson-Carlgren N; Timmers PRHJ; Hwang S-J; Enroth S; Gustafsson S; Vosa U; Chen Y; Siegbahn A; Reiner A; Johansson Å; Thorand B; Gigante B; Hayward C; Herder C; Gieger C; Langenberg C; Levy D; Zhernakova DV; Smith JG; Campbell H; Sundstrom J; Danesh J; Michaëlsson K; Suhre K; Lind L; Wallentin L; Padyukov L; Landén M; Wareham NJ; Göteson A; Hansson O; Eriksson P; Strawbridge RJ; Assimes TL; Esko T; Gyllensten U; Baillie JK; Paul DS; Joshi PK; Butterworth AS; Mälarstig A; Pirastu N; Wilson JF; Peters JE
Corrigendum: NATURE COMMUNICATIONS. 2021;12(1):995

Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V; Mägi R; Hottenga J-J; Grallert H; Perry JRB; Bouatia-Naji N; Marullo L; Rybin D; Jansen R; Min JL; Dimas AS; Ulrich A; Zudina L; Gådin JR; Jiang L; Faggian A; Bonnefond A; Fadista J; Stathopoulou MG; Isaacs A; Willems SM; Navarro P; Tanaka T; Jackson AU; Montasser ME; O'Connell JR; Bielak LF; Webster RJ; Saxena R; Stafford JM; Pourcain BS; Timpson NJ; Salo P; Shin S-Y; Amin N; Smith AV; Li G; Verweij N; Goel A; Ford I; Johnson PCD; Johnson T; Kapur K; Thorleifsson G; Strawbridge RJ; Rasmussen-Torvik LJ; Esko T; Mihailov E; Fall T; Fraser RM; Mahajan A; Kanoni S; Giedraitis V; Kleber ME; Silbernagel G; Meyer J; Müller-Nurasyid M; Ganna A; Sarin A-P; Yengo L; Shungin D; Luan J; Horikoshi M; An P; Sanna S; Boettcher Y; Rayner NW; Nolte IM; Zemunik T; Iperen EV; Kovacs P; Hastie ND; Wild SH; McLachlan S; Campbell S; Polasek O; Carlson O; Egan J; Kiess W; Willemsen G; Kuusisto J; Laakso M; Dimitriou M; Hicks AA; Rauramaa R; Bandinelli S; Thorand B; Liu Y; Miljkovic I; Lind L; Doney A; Perola M; Hingorani A; Kivimaki M; Kumari M; Bennett AJ; Groves CJ; Herder C; Koistinen HA; Kinnunen L; Faire UD; Bakker SJL; Uusitupa M; Palmer CNA; Jukema JW; Sattar N; Pouta A; Snieder H; Boerwinkle E; Pankow JS; Magnusson PK; Krus U; Scapoli C; de Geus EJCN; Blüher M; Wolffenbuttel BHR; Province MA; Abecasis GR; Meigs JB; Hovingh GK; Lindström J; Wilson JF; Wright AF; Dedoussis GV; Bornstein SR; Schwarz PEH; Tönjes A; Winkelmann BR; Boehm BO; März W; Metspalu A; Price JF; Deloukas P; Körner A; Lakka TA; Keinanen-Kiukaanniemi SM; Saaristo TE; Bergman RN; Tuomilehto J; Wareham NJ; Langenberg C; Männistö S; Franks PW; Hayward C; Vitart V; Kaprio J; Visvikis-Siest S; Balkau B; Altshuler D; Rudan I; Stumvoll M; Campbell H; van Duijn CM; Gieger C; Illig T; Ferrucci L; Pedersen NL; Pramstaller PP; Boehnke M; Frayling TM; Shuldiner AR; Peyser PA; Kardia SLR; Palmer LJ; Penninx BW; Meneton P; Harris TB; Navis G; Harst PVD; Smith GD; Forouhi NG; Loos RJF; Salomaa V; Soranzo N; Boomsma DI; Groop L; Tuomi T; Hofman A; Munroe PB; Gudnason V; Siscovick DS; Watkins H; Lecoeur C; Vollenweider P; Franco-Cereceda A; Eriksson P; Jarvelin M-R; Stefansson K; Hamsten A; Nicholson G; Karpe F; Dermitzakis ET; Lindgren CM; McCarthy MI; Froguel P; Kaakinen MA; Lyssenko V; Watanabe RM; Ingelsson E; Florez JC; Dupuis J; Barroso I; Morris AP; Prokopenko I; Meta-Analyses of Glucose and Insulin-related trait
Review: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2019;6:182

Endothelial/Epithelial Mesenchymal Transition in Ascending Aortas of Patients With Bicuspid Aortic Valve.

Maleki S; Poujade F-A; Bergman O; Gådin JR; Simon N; Lång K; Franco-Cereceda A; Body SC; Björck HM; Eriksson P
Corrigendum: FRONTIERS IN PHYSIOLOGY. 2017;8:730

Corrigendum: Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor.

Gillis E; Kumar AA; Luyckx I; Preuss C; Cannaerts E; van de Beek G; Wieschendorf B; Alaerts M; Bolar N; Vandeweyer G; Meester J; Wünnemann F; Gould RA; Zhurayev R; Zerbino D; Mohamed SA; Mital S; Mertens L; Björck HM; Franco-Cereceda A; McCallion AS; Van Laer L; Verhagen JMA; van de Laar IMBH; Wessels MW; Messas E; Goudot G; Nemcikova M; Krebsova A; Kempers M; Salemink S; Duijnhouwer T; Jeunemaitre X; Albuisson J; Eriksson P; Andelfinger G; Dietz HC; Verstraeten A; Loeys BL; Mibava Leducq Consortium
Corrigendum: NATURE COMMUNICATIONS. 2015;6:6506

Erratum: miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.

Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nakagami F; Heymann HM; Chernogubova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Editorial comment: CIRCULATION. 2012;126(15):1815-1817

Quest for genes and mechanisms linking the human chromosome 9p21.3 locus to cardiovascular disease.

Hamsten A; Eriksson P
Corrigendum: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. 2012;41(2):471

Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: a study of 300 patients undergoing open-heart surgery (vol 40, pg e118, 2011)

Jackson V; Petrini J; Caidahl K; Eriksson MJ; Liska J; Eriksson P; Franco-Cereceda A
Corrigendum: JOURNAL OF INTERNAL MEDICINE. 2011;269(4):468

Low plasma adiponectin concentration is associated with myocardial infarction in young individuals (vol 268, pg 194, 2010)

Persson J; Lindberg K; Gustafsson TP; Eriksson P; Paulsson-Berne G; Lundman P
Letter: JOURNAL OF INTERNAL MEDICINE. 2008;264(6):613-617

Vaccination, a human model of inflammation, activates systemic inflammation but does not trigger proinflammatory gene expression in adipose tissue.

Ekström M; Eriksson P; Tornvall P
Letter: NATURE GENETICS. 2008;40(12):1387-1388

Lack of support for association between common variation in TNFSF4 and myocardial infarction in a German population Reply

Wang X; Ria M; Eriksson P; de Faire U; Hamsten A; Paigen B
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2006;1085:133-138

The intraluminal thrombus as a source of proteolytic activity.

Swedenborg J; Eriksson P
Corrigendum: EUROPEAN HEART JOURNAL. 2005;26(9):942

'Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction' (vol 25, pg 1447, 2004)

Edfeldt K; Bennet AM; Eriksson P; Frostegård J; Wiman B; Hamsten A; Hansson GK; de Faire U; Yan ZQ
Letter: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2005;35(2):154-155

Effects of free fatty acids and a triglyceride-rich fat emulsion on endothelial nitric oxide synthase.

Halle M; Eriksson P; Tornvall P
Review: ACTA CHIRURGICA BELGICA. 2004;104(6):606-608

Influence of the intraluminal thrombus in abdominal aortic aneurysms.

Swedenborg J; Kazi M; Eriksson P; Hedin U
Published conference paper: BRITISH JOURNAL OF SURGERY. 2003;91(1):86-89

Genetic approach to the role of cysteine proteases in the expansion of abdominal aortic aneurysms.

Eriksson P; Jones KG; Brown LC; Greenhalgh RM; Hamsten A; Powell JT
Published conference paper: JOURNAL OF VASCULAR SURGERY. 2003;38(6):1283-1292

Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall.

Kazi M; Thyberg J; Religa P; Roy J; Eriksson P; Hedin U; Swedenborg J
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2003;23(1):6-7

Thrombospondins and premature coronary artery disease: time to go beyond genotype-phenotype association studies.

Hamsten A; Eriksson P
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):48-49

Genetic and structural evaluation of fatty acid transport protein-4 (FATP4) in relation to markers of the insulin resistance syndrome

Gertow K; Bellanda M; Sunnerhagen M; Eriksson P; Boquist S; Hamsten A; Fisher R
Letter: DIABETOLOGIA. 2001;44(5):654-655

Tumour necrosis factor-alpha (TNF-alpha) polymorphisms-857C/A and -863C/A are associated with TNF-alpha secretion from human adipose tissue.

Skoog T; Eriksson P; Hoffstedt J; Rydén M; Hamsten A; Armer P
Corrigendum: DIABETES. 1998;47(9):1532

Leptin secretion from subcutaneous and visceral adipose tissue in women (vol 47, pg 913, 1998)

Van Harmelen V; Reynisdottir S; Eriksson P; Thörne A; Hoffstedt J; Lönnqvist F; Arner P
Review: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 1997;29(5):731-742

The role of chromatin in transcriptional regulation.

Li Q; Wrange O; Eriksson P
Review: BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY. 1995;8(2):345-363

Fibrinolysis and atherosclerosis.

Hamsten A; Eriksson P
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Forskningsbidrag

Aortic valve disease and associated thoracic aortic aneurysm

Swedish Research Council

1 January 2021 - 31 December 2023
THORACIC AORTIC ANEURYSM PATHOLOGY

Swedish Heart-Lung Foundation

1 January 2019 - 31 December 2021
Molecular aspects of thoracic aortic aneurysm pathology

Swedish Research Council

1 January 2017 - 31 December 2020
MECHANISMS OF FORMATION, GROWTH AND RUPTURE OF AORTIC ANEURYSMS

Swedish Research Council

1 January 2012 - 31 December 2016
MIBAVA-Mechanistic Interrogation of Bicuspid Aortic Valve associated Aortopathy

Fondation Leducq

1 January 2012
MECHANISMS OF FORMATION, GROWTH AND RUPTURE OF AORTIC ANEURYSMS

Swedish Research Council

1 January 2009 - 31 December 2011

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