Jan-Eric Litton

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

Jag är professor emeritus i biomedicinsk datateknik. Mitt huvudsakliga intresse handlar om biomedicinsk datateknik, text- och datamining, bildanalys och modellering, internetrelaterad forskning inom biomedicin samt matematisk modellering i biomedicinsk forskning och 3D-modeller.

Utbildning:
* Docent i medicinsk teknik, Karolinska Institutet 1990
* Post Doc vid the Research Medicine Department of Lawrence Berkeley
Laboratory and Donner Laboratory of the University of California, USA
1986-1987
* Medicine doktor, Karolinska Institutet 1983
* Grundutbildning sektionen för elektroteknik KTH, Stockholm 1975

Forskningsbeskrivning

Forskningsprojekt:
• BBMRI.se
• Biobanking
• EU-Biobanking
• LifeGene
• E-epidemiologi: web-baserade enkäter
• E-epidemiologi: telefonen som verktyg
• E-epidemiologi: datorprogram via internet
• Textmining

Artiklar

Article: BIOPRESERVATION AND BIOBANKING. 2018;16(2):97-105

Enhancing Reuse of Data and Biological Material in Medical Research: From FAIR to FAIR-Health.

Holub P; Kohlmayer F; Prasser F; Mayrhofer MT; Schlünder I; Martin GM; Casati S; Koumakis L; Wutte A; Kozera Ł; Strapagiel D; Anton G; Zanetti G; Sezerman OU; Mendy M; Valík D; Lavitrano M; Dagher G; Zatloukal K; van Ommen GB; Litton J-E
Article: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION. 2017;24(5):950-957

E-Science technologies in a workflow for personalized medicine using cancer screening as a case study.

Spjuth O; Karlsson A; Clements M; Humphreys K; Ivansson E; Dowling J; Eklund M; Jauhiainen A; Czene K; Grönberg H; Sparén P; Wiklund F; Cheddad A; Pálsdóttir Þ; Rantalainen M; Abrahamsson L; Laure E; Litton J-E; Palmgren J
Article: BIOPRESERVATION AND BIOBANKING. 2017;15(3):270-276

Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.

Doucet M; Becker KF; Björkman J; Bonnet J; Clément B; Daidone M-G; Duyckaerts C; Erb G; Haslacher H; Hofman P; Huppertz B; Junot C; Lundeberg J; Metspalu A; Lavitrano M; Litton J-E; Moore HM; Morente M; Naimi B-Y; Oelmueller U; Ollier B; Parodi B; Ruan L; Stanta G; Turano P; Vaught J; Watson P; Wichmann H-E; Yuille M; Zaomi M; Zatloukal K; Dagher G
Article: BIOPRESERVATION AND BIOBANKING. 2016;14(6):559-562

BBMRI-ERIC Directory: 515 Biobanks with Over 60 Million Biological Samples.

Holub P; Swertz M; Reihs R; van Enckevort D; Müller H; Litton J-E
Article: BIOPRESERVATION AND BIOBANKING. 2016;14(4):298-306

Toward Global Biobank Integration by Implementation of the Minimum Information About BIobank Data Sharing (MIABIS 2.0 Core).

Merino-Martinez R; Norlin L; van Enckevort D; Anton G; Schuffenhauer S; Silander K; Mook L; Holub P; Bild R; Swertz M; Litton J-E
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2016;24(4):521-528

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research.

Spjuth O; Krestyaninova M; Hastings J; Shen H-Y; Heikkinen J; Waldenberger M; Langhammer A; Ladenvall C; Esko T; Persson M-Å; Heggland J; Dietrich J; Ose S; Gieger C; Ried JS; Peters A; Fortier I; de Geus EJC; Klovins J; Zaharenko L; Willemsen G; Hottenga J-J; Litton J-E; Karvanen J; Boomsma DI; Groop L; Rung J; Palmgren J; Pedersen NL; McCarthy MI; van Duijn CM; Hveem K; Metspalu A; Ripatti S; Prokopenko I; Harris JR
Article: BUNDESGESUNDHEITSBLATT-GESUNDHEITSFORSCHUNG-GESUNDHEITSSCHUTZ. 2016;59(3):379-384

BBMRI-ERIC: the novel gateway to biobanks. From humans to humans.

Mayrhofer MT; Holub P; Wutte A; Litton J-E
Article: JOURNAL OF PROTEOMICS. 2015;127(Pt B):414-416

The EuPA Biobank Initiative: Meeting the future challenges of biobanking in proteomics & systems medicine.

Wheelock ÅM; Paulson L; Litton J-E; EuPA Biobank Initiative Group
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2015;23(7):893-900

BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres.

van Ommen G-JB; Törnwall O; Bréchot C; Dagher G; Galli J; Hveem K; Landegren U; Luchinat C; Metspalu A; Nilsson C; Solesvik OV; Perola M; Litton J-E; Zatloukal K
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2015;23(1):22-28

Toward a common language for biobanking.

Fransson MN; Rial-Sebbag E; Brochhausen M; Litton J-E
Article: JOURNAL OF BIOMEDICAL SEMANTICS. 2013;4(1):23

Developing a semantically rich ontology for the biobank-administration domain.

Brochhausen M; Fransson MN; Kanaskar NV; Eriksson M; Merino-Martinez R; Hall RA; Norlin L; Kjellqvist S; Hortlund M; Topaloglu U; Hogan WR; Litton J-E
Article: BIOPRESERVATION AND BIOBANKING. 2013;11(1):19-24

The Swedish cervical cytology biobank: sample handling and storage process.

Perskvist N; Norman I; Eklund C; Litton J-E; Dillner J
Article: NEW BIOTECHNOLOGY. 2013;30(2):109-113

Workshop on laboratory protocol standards for the Molecular Methods Database.

Klingström T; Soldatova L; Stevens R; Roos TE; Swertz MA; Müller KM; Kalaš M; Lambrix P; Taussig MJ; Litton J-E; Landegren U; Bongcam-Rudloff E
Article: PLOS ONE. 2013;8(4):e61644

The validity of self-initiated, event-driven infectious disease reporting in general population cohorts.

Merk H; Kühlmann-Berenzon S; Bexelius C; Sandin S; Litton J-E; Linde A; Nyrén O
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2012;20(11):1105-1111

Toward a roadmap in global biobanking for health.

Harris JR; Burton P; Knoppers BM; Lindpaintner K; Bledsoe M; Brookes AJ; Budin-Ljøsne I; Chisholm R; Cox D; Deschênes M; Fortier I; Hainaut P; Hewitt R; Kaye J; Litton J-E; Metspalu A; Ollier B; Palmer LJ; Palotie A; Pasterk M; Perola M; Riegman PHJ; van Ommen G-J; Yuille M; Zatloukal K
Article: BIOPRESERVATION AND BIOBANKING. 2012;10(4):343-348

A Minimum Data Set for Sharing Biobank Samples, Information, and Data: MIABIS.

Norlin L; Fransson MN; Eriksson M; Merino-Martinez R; Anderberg M; Kurtovic S; Litton J-E
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2012;27(7):561-566

Estimating physical activity using a cell phone questionnaire sent by means of short message service (SMS): a randomized population-based study.

Lagerros YT; Sandin S; Bexelius C; Litton J-E; Löf M
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2011;13(3):e70

Estimation of physical activity levels using cell phone questionnaires: a comparison with accelerometry for evaluation of between-subject and within-subject variations.

Bexelius C; Sandin S; Trolle Lagerros Y; Litton J-E; Löf M
Article: DRUG METABOLISM AND DISPOSITION. 2011;39(2):247-255

Influence of Cremophor EL and genetic polymorphisms on the pharmacokinetics of paclitaxel and its metabolites using a mechanism-based model.

Fransson MN; Gréen H; Litton J-E; Friberg LE
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2011;26(1):67-77

LifeGene--a large prospective population-based study of global relevance.

Almqvist C; Adami H-O; Franks PW; Groop L; Ingelsson E; Kere J; Lissner L; Litton J-E; Maeurer M; Michaëlsson K; Palmgren J; Pershagen G; Ploner A; Sullivan PF; Tybring G; Pedersen NL
Article: METHODS IN MOLECULAR BIOLOGY. 2011;675:343-361

Biobank informatics: connecting genotypes and phenotypes.

Litton J-E
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2010;39(5):1383-1393

Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies.

Fortier I; Burton PR; Robson PJ; Ferretti V; Little J; L'Heureux F; Deschênes M; Knoppers BM; Doiron D; Keers JC; Linksted P; Harris JR; Lachance G; Boileau C; Pedersen NL; Hamilton CM; Hveem K; Borugian MJ; Gallagher RP; McLaughlin J; Parker L; Potter JD; Gallacher J; Kaaks R; Liu B; Sprosen T; Vilain A; Atkinson SA; Rengifo A; Morton R; Metspalu A; Wichmann HE; Tremblay M; Chisholm RL; Garcia-Montero A; Hillege H; Litton J-E; Palmer LJ; Perola M; Wolffenbuttel BHR; Peltonen L; Hudson TJ
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2010;25(10):693-702

Interactive voice response and web-based questionnaires for population-based infectious disease reporting.

Bexelius C; Merk H; Sandin S; Nyrén O; Kühlmann-Berenzon S; Linde A; Litton J-E
Article: OTOLOGY & NEUROTOLOGY. 2010;31(5):708-714

An internet-based hearing test for simple audiometry in nonclinical settings: preliminary validation and proof of principle.

Honeth L; Bexelius C; Eriksson M; Sandin S; Litton J-E; Rosenhall U; Nyrén O; Bagger-Sjöbäck D
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2010;12(1):e2

Measures of physical activity using cell phones: validation using criterion methods.

Bexelius C; Löf M; Sandin S; Trolle Lagerros Y; Forsum E; Litton J-E
Article: JOURNAL OF BIOMEDICAL INFORMATICS. 2009;42(6):1029-1034

Unleashing genotypes in epidemiology - A novel method for managing high throughput information.

Olund G; Brinne A; Lindqvist P; Litton J-E
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2009;24(2):73-81

SMS versus telephone interviews for epidemiological data collection: feasibility study estimating influenza vaccination coverage in the Swedish population.

Bexelius C; Merk H; Sandin S; Ekman A; Nyrén O; Kühlmann-Berenzon S; Linde A; Litton J-E
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2008;10(4):e32

Evaluation of an internet-based hearing test--comparison with established methods for detection of hearing loss.

Bexelius C; Honeth L; Ekman A; Eriksson M; Sandin S; Bagger-Sjöbäck D; Litton J-E
Article: BRIEFINGS IN BIOINFORMATICS. 2008;9(1):14-24

Biobanking for Europe.

Yuille M; van Ommen G-J; Bréchot C; Cambon-Thomsen A; Dagher G; Landegren U; Litton J-E; Pasterk M; Peltonen L; Taussig M; Wichmann H-E; Zatloukal K
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2007;15(7):718-723

The federated database--a basis for biobank-based post-genome studies, integrating phenome and genome data from 600,000 twin pairs in Europe.

Muilu J; Peltonen L; Litton J-E
Article: IBM SYSTEMS JOURNAL. 2007;46(1):171-182

BIMS:: An information management system for biobanking in the 21st century

Olund G; Lindqvist P; Litton J-E
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2007;22(5):293-300

Optimizing the design of web-based questionnaires--experience from a population-based study among 50,000 women.

Ekman A; Klint A; Dickman PW; Adami H-O; Litton J-E
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2006;21(2):103-111

Feasibility of using web-based questionnaires in large population-based epidemiological studies.

Ekman A; Dickman PW; Klint A; Weiderpass E; Litton J-E
Article: CANCER CAUSES & CONTROL. 2005;16(6):765-772

Can we trust cancer information on the Internet?--A comparison of interactive cancer risk sites.

Ekman A; Hall P; Litton J-E
Article: TWIN RESEARCH AND HUMAN GENETICS. 2003;6(5):383-390

Data modeling and data communication in GenomEUtwin.

Litton J-E; Muilu J; Björklund A; Leinonen A; Pedersen NL
Article: ADDICTION BIOLOGY. 2000;5(1):97-99

Reduced [¹¹C]flumazenil radioligand binding in the thalamus in alcoholics.

Neiman J; Litton JE
Article: ACTA NEUROLOGICA SCANDINAVICA. 1998;97(5):279-286

Regional increases in [11C]flumazenil binding after epilepsy surgery.

Savic I; Blomqvist G; Halldin C; Litton JE; Gulyas B
Article: JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY. 1997;21(6):907-909

Input function in PET brain studies using MR-defined arteries.

Litton JE
Article: PHYSICS IN MEDICINE AND BIOLOGY. 1997;42(8):1653-1660

Improved receptor analysis in PET using a priori information from in vitro binding assays.

Litton JE; Hall H; Blomqvist G
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Alla övriga publikationer

Review: BIOPRESERVATION AND BIOBANKING. 2018;16(3):233-241

Launch of an Infrastructure for Health Research: BBMRI-ERIC.

Litton J-E
Editorial comment: BIOPRESERVATION AND BIOBANKING. 2017;15(6):491-493

Global Biobank Week: Toward Harmonization in Biobanking.

Henderson MK; Matharoo-Ball B; Schacter B; Kozlakidis Z; Smits E; Törnwall O; Litton J-E
Editorial comment: NATURE. 2017;541(7638):437

We must urgently clarify data-sharing rules.

Litton J-E
Letter: EUROPEAN JOURNAL OF HUMAN GENETICS. 2014;22(9):1055-1057

ERIC: a new governance tool for biobanking.

Reichel J; Lind A-S; Hansson MG; Litton J-E
Letter: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;91(3):577-578

Questioning the limits of genomic privacy.

Knoppers BM; Dove ES; Litton J-E; Nietfeld JJ
Letter: NATURE REVIEWS CANCER. 2011;11(12):895

The flexibility of biobanking with the Bio-PIN system

Nietfeld JJ; Sugarman J; Litton J-E
Letter: NATURE BIOTECHNOLOGY. 2011;29(9):795-797

Comprehensive catalog of European biobanks.

Wichmann H-E; Kuhn KA; Waldenberger M; Schmelcher D; Schuffenhauer S; Meitinger T; Wurst SHR; Lamla G; Fortier I; Burton PR; Peltonen L; Perola M; Metspalu A; Riegman P; Landegren U; Taussig MJ; Litton J-E; Fransson MN; Eder J; Cambon-Thomsen A; Bovenberg J; Dagher G; van Ommen G-J; Griffith M; Yuille M; Zatloukal K
Editorial comment: BIOPRESERVATION AND BIOBANKING. 2011;9(3):213-216

What are the main roadblocks to transnational biobank collaboration, and how can we overcome them?

Watson PH; Ravid R; Eng CB; Litton J-E; Vaught J; Matusan A
Letter: NATURE. 2011;472(7344):418

Bio-PIN could cut biobanking risks.

Nietfeld JJ; Litton J-E
Review: NATURE REVIEWS CANCER. 2011;11(4):303-308

The Bio-PIN: a concept to improve biobanking.

Nietfeld JJ; Sugarman J; Litton J-E
Review: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2007;22(5):285-292

New times, new needs; e-epidemiology.

Ekman A; Litton J-E

Om mig

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