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17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use
Farzan N, Vijverberg Sj, Hernandez-pacheco N, Bel Ehd, Berce V, Bønnelykke K, et al
Allergy 2018;73(10):2083-2088

DNA methylation in childhood asthma: an epigenome-wide meta-analysis
Bios Consortium, Xu Cj, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, et al
The Lancet. Respiratory medicine 2018;6(5):379-388

Environmental peanut exposure increases the risk of peanut sensitization in high-risk children
Brough Ha, Kull I, Richards K, Hallner E, Söderhäll C, Douiri A, et al
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2018;48(5):586-593

Genetic and epigenetic regulation of YKL-40 in childhood
Guerra S, Melén E, Sunyer J, Xu Cj, Lavi I, Benet M, et al
The Journal of allergy and clinical immunology 2018;141(3):1105-1114

PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze
Niespodziana K, Stenberg-hammar K, Megremis S, Cabauatan Cr, Napora-wijata K, Vacal Pc, et al
Nature communications 2018;9(1):2382-

Preventing Atopic Dermatitis and ALLergies in Children-the PreventADALL study
Study Group, Lødrup Carlsen Kc, Rehbinder Em, Skjerven Ho, Carlsen Mh, Fatnes Ta, et al
Allergy 2018;73(10):2063-2070

Prognosis of Preschool Eczema and Factors of Importance for Remission
Johansson Ek, Bergström A, Kull I, Lind T, Söderhäll C, Melén E, et al
Acta dermato-venereologica 2018;98(7):630-635

Reduced CDHR3 expression in children wheezing with rhinovirus
Stenberg Hammar K, Niespodziana K, Van Hage M, Kere J, Valenta R, Hedlin G, et al
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2018;29(2):200-206

A longitudinal assessment of circulating YKL-40 levels in preschool children with wheeze
James A, Stenberg Hammar K, Reinius L, Konradsen Jr, Dahlén Se, Söderhäll C, et al
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2017;28(1):79-85

Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure
Gruzieva O, Xu Cj, Breton Cv, Annesi-maesano I, Antó Jm, Auffray C, et al
Environmental health perspectives 2017;125(1):104-110

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up
Gref A, Merid Sk, Gruzieva O, Ballereau S, Becker A, Bellander T, et al
American journal of respiratory and critical care medicine 2017;195(10):1373-1383

Hypomethylation of HOXA4 promoter is common in Silver-Russell syndrome and growth restriction and associates with stature in healthy children
Muurinen M, Hannula-jouppi K, Reinius Le, Söderhäll C, Merid Sk, Bergström A, et al
Scientific reports 2017;7(1):15693-

IgE sensitization in relation to preschool eczema and filaggrin mutation
Johansson Ek, Bergström A, Kull I, Lind T, Söderhäll C, Van Hage M, et al
The Journal of allergy and clinical immunology 2017;140(6):1572-1579.e5

Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma
Acevedo N, Ezer S, Kebede Merid S, Gaertner Vd, Söderhäll C, D'amato M, et al
PloS one 2017;12(5):e0176568-

Rhinovirus and preschool wheeze
Stenberg-hammar K, Hedlin G, Söderhäll C
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2017;28(6):513-520

The emerging landscape of dynamic DNA methylation in early childhood
Xu Cj, Bonder Mj, Söderhäll C, Bustamante M, Baïz N, Gehring U, et al
BMC genomics 2017;18(1):25-

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Joubert Br, Felix Jf, Yousefi P, Bakulski Km, Just Ac, Breton C, et al
American journal of human genetics 2016;98(4):680-96

Globin mRNA reduction for whole-blood transcriptome sequencing
Krjutškov K, Koel M, Roost Am, Katayama S, Einarsdottir E, Jouhilahti Em, et al
Scientific reports 2016;6():31584-

Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease
Bioair (longitudinal Assessment Of Clinical Course And Biomarkers In Severe Chronic Airway Disease) Consortium, James Aj, Reinius Le, Verhoek M, Gomes A, Kupczyk M, et al
American journal of respiratory and critical care medicine 2016;193(2):131-42

Rhinovirus-specific antibody responses in preschool children with acute wheeze reflect severity of respiratory symptoms
Stenberg-hammar K, Niespodziana K, Söderhäll C, James A, Cabauatan Cr, Konradsen Jr, et al
Allergy 2016;71(12):1728-1735

Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease
Matsson H, Söderhäll C, Einarsdottir E, Lamontagne M, Gudmundsson S, Backman H, et al
BMC pulmonary medicine 2016;16(1):146-

Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes
Acevedo N, Reinius Le, Vitezic M, Fortino V, Söderhäll C, Honkanen H, et al
Clinical epigenetics 2015;7():34-

Associations between the 17q21 region and allergic rhinitis in 5 birth cohorts
Fuertes E, Söderhäll C, Acevedo N, Becker A, Brauer M, Chan-yeung M, et al
The Journal of allergy and clinical immunology 2015;135(2):573-6

DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection
Everson Tm, Lyons G, Zhang Hm, Soto-ramirez N, Lockett Ga, Patil Vk, et al
GENOME MEDICINE 2015;:89-

Fine mapping analysis confirms and strengthens linkage of four chromosomal regions in familial hypospadias
Söderhäll C, Körberg Ib, Thai Ht, Cao J, Chen Y, Zhang X, et al
European journal of human genetics : EJHG 2015;23(4):516-22

GIMAP GTPase family genes: potential modifiers in autoimmune diabetes, asthma, and allergy
Finnish Pediatric Diabetes Registry, Heinonen Mt, Laine Ap, Söderhäll C, Gruzieva O, Rautio S, et al
Journal of immunology (Baltimore, Md. : 1950) 2015;194(12):5885-94

Meta-analysis identifies seven susceptibility loci involved in the atopic march
Marenholz I, Esparza-gordillo J, Rüschendorf F, Bauerfeind A, Strachan Dp, Spycher Bd, et al
Nature communications 2015;6():8804-

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Australian Asthma Genetics Consortium (aagc), Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, et al
Nature genetics 2015;47(12):1449-1456

Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus
Acevedo N, Reinius Le, Greco D, Gref A, Orsmark-pietras C, Persson H, et al
Human molecular genetics 2015;24(3):875-90

Transcriptome analysis of controlled and therapy-resistant childhood asthma reveals distinct gene expression profiles
Persson H, Kwon At, Ramilowski Ja, Silberberg G, Söderhäll C, Orsmark-pietras C, et al
The Journal of allergy and clinical immunology 2015;136(3):638-48

A case with bladder exstrophy and unbalanced X chromosome rearrangement
Soderhall C, Lundin J, Lagerstedt-robinson K, Grigelioniene G, Lackgren G, Kockum Cc, et al
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 2014;24(4):353-9

Differential DNA methylation and microRNA expression in skin-homing CLA plus T cells of atopic eczema patients
Scheynius A, Acevedo N, Bruhn S, Andersson A, Wikberg G, Lundeberg L, et al
EXPERIMENTAL DERMATOLOGY 2014;:2-3

Differential DNA methylation and microRNA expression in skin-homing CLA(+) T cells of atopic eczema patients
Acevedo N, Bruhn S, Andersson A, Wikberg G, Lundberg L, Soderhall C, et al
ALLERGY 2014;:583-583

Infantile eczema: Prognosis and risk of asthma and rhinitis in preadolescence
Ballardini N, Bergström A, Böhme M, Van Hage M, Hallner E, Johansson E, et al
The Journal of allergy and clinical immunology 2014;133(2):594-6

Neuropeptide S receptor 1 (NPSR1) activates cancer-related pathways and is widely expressed in neuroendocrine tumors
Pulkkinen V, Ezer S, Sundman L, Hagstrom J, Remes S, Soderhall C, et al
VIRCHOWS ARCHIV 2014;465(2):173-83

Neuropeptide S receptor 1 (NPSR1) activates cancer-related pathways and is widely expressed in neuroendocrine tumors (vol 465, pg 173, 2014)
Pulkkinen V, Ezer S, Sundman L, Hagstrom J, Remes S, Soderhall C, et al
VIRCHOWS ARCHIV 2014;465(2):251-251

NPSR1 polymorphisms influence recurrent abdominal pain in children: a population-based study
Henström M, Zucchelli M, Söderhäll C, Bergström A, Kere J, Melén E, et al
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2014;26(10):1417-25

Subnormal levels of vitamin D are associated with acute wheeze in young children
Stenberg Hammar K, Hedlin G, Konradsen Jr, Nordlund B, Kull I, Giske Cg, et al
Acta paediatrica (Oslo, Norway : 1992) 2014;103(8):856-61

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis
Weidinger S, Willis-owen Sag, Kamatani Y, Baurecht H, Morar N, Liang Lm, et al
HUMAN MOLECULAR GENETICS 2013;22(23):4841-56

Analyses of genetic association and DNA methylation in the ORMDL3/GSDMB locus
Acevedo N, Reinius L, Gref A, Melen E, Saaf A, Pershagen G, et al
EUROPEAN RESPIRATORY JOURNAL 2013;:-

Decreased DNA methylation in the ORMDL3 promoter of children with asthma and severe asthma
Acevedo N, Reinius Le, Gref A, Greco D, Pietras Co, Pershagen G, et al
ALLERGY 2013;:684-685

DNA methylation in the Neuropeptide S Receptor 1 (NPSR1) promoter in relation to asthma and environmental factors
Bioair Study Group, Reinius Le, Gref A, Sääf A, Acevedo N, Joerink M, et al
PloS one 2013;8(1):e53877-

Eczema severity in preadolescent children and its relation to sex, filaggrin mutations, asthma, rhinitis, aggravating factors and topical treatment: a report from the BAMSE birth cohort
Ballardini N, Kull I, Söderhäll C, Lilja G, Wickman M, Wahlgren Cf
The British journal of dermatology 2013;168(3):588-94

Genome-wide association study of body mass index in 23 000 individuals with and without asthma
Melén E, Granell R, Kogevinas M, Strachan D, Gonzalez Jr, Wjst M, et al
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2013;43(4):463-74

Increased expression of bitter taste receptors on peripheral blood leukocytes from children with severe asthma compared to healthy controls
James A, Orsmark-pietras C, Melen E, Konradsen J, Nordlund B, Soderhall C, et al
EUROPEAN RESPIRATORY JOURNAL 2013;:-

Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma
Acevedo N, Sääf A, Söderhäll C, Melén E, Mandelin J, Pietras Co, et al
PloS one 2013;8(4):e60111-

Rule-based models of the interplay between genetic and environmental factors in childhood allergy
Bornelöv S, Sääf A, Melén E, Bergström A, Torabi Moghadam B, Pulkkinen V, et al
PloS one 2013;8(11):e80080-

The chitinase-like protein YKL-40: a possible biomarker of inflammation and airway remodeling in severe pediatric asthma
Konradsen Jr, James A, Nordlund B, Reinius Le, Söderhäll C, Melén E, et al
The Journal of allergy and clinical immunology 2013;132(2):328-35.e5

Transcriptome analysis of controlled and problematic severe childhood asthma
Persson H, Ramilowski J, Kwon A, Orsmark-pietras C, Soderhall C, Nordlund B, et al
EUROPEAN RESPIRATORY JOURNAL 2013;:-

Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics
Orsmark-pietras C, James A, Konradsen Jr, Nordlund B, Söderhäll C, Pulkkinen V, et al
The European respiratory journal 2013;42(1):65-78

Centrosomal Localization of the Psoriasis Candidate Gene Product, CCHCR1, Supports a Role in Cytoskeletal Organization
Tervaniemi Mh, Siitonen Ha, Soderhall C, Minhas G, Vuola J, Tiala I, et al
PLOS ONE 2012;7(11):e49920-

Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility
Reinius Le, Acevedo N, Joerink M, Pershagen G, Dahlén Se, Greco D, et al
PloS one 2012;7(7):e41361-

Evaluating the Influence of DNA Methylation on the Susceptibility to Asthma: NPSR1 and ORMDL3 as Model Candidate Genes
Acevedo N, Johansson Le, Pietras Co, Dahlen Se, Melen E, Pershagen G, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2012;76(2):203-204

Filaggrin mutations increase the risk for persistent dry skin and eczema independent of sensitization
Bohme M, Soderhall C, Kull I, Bergstrom A, Van Hage M, Wahlgren Cf
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2012;129(4):1153-5

Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci
Svenningsson A, Soderhall C, Persson S, Lundberg F, Luthman H, Chung E, et al
JOURNAL OF HUMAN GENETICS 2012;57(2):115-21

Influence of DNA methylation on the susceptibility to asthma: NPSR1 and ORMDL3 as model candidate genes and the limitations of using whole blood as DNA source in methylation studies
Acevedo N, Johansson L, Pietras Co, Dahlen S, Melen E, Pershagen G, et al
ALLERGY 2012;:621-621

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
Early Genetics Lifecourse Epidemio, Genetics Overweight Young Adults G, Australian Asthma Genetics Consort, Paternoster L, Standl M, Chen Cm, et al
NATURE GENETICS 2012;44(2):187-92

A comprehensive analysis of the COL29A1 gene does not support a role in eczema
Naumann A, Soderhall C, Folster-holst R, Baurecht H, Harde V, Muller-wehling K, et al
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2011;127(5):1187-94.e7

Dna Methylation In The Promoter Of Neuropeptide S Receptor 1 (NPSR1) In Relation To Respiratory Syndromes
Johansson Le, Kupczyk M, Soderhall C, D'amato M, Middelveld R, Dahlen Se, et al
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2011;:-

Genome Wide Transcriptome Analysis Suggests Novel Mechanisms In Severe Childhood Asthma
Pietras Co, Konradsen J, Nordlund B, Soderhall C, Pedroletti C, Hedlin Gl, et al
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2011;:-

The asthma candidate gene NPSR1 mediates isoform specific downstream signalling
Pietras Co, Vendelin J, Anedda F, Bruce S, Adner M, Sundman L, et al
BMC pulmonary medicine 2011;11():39-

22q11.2 microduplication in two patients with bladder exstrophy and hearing impairment
Lundin J, Soderhall C, Lunden L, Hammarsjo A, White I, Schoumans J, et al
EUROPEAN JOURNAL OF MEDICAL GENETICS 2010;53(2):61-5

Airway Inflammation In COPD And Asthma Is Associated With Elevated Serum Chitotriosidase Activity In A Genotype Dependent Manner
Bioair Study Grp, James A, Johansson L, Boot R, Kupczyk M, Middelveld R, et al
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 2010;:-

A large-scale, consortium-based genomewide association study of asthma
Gabriel Consortium, Moffatt Mf, Gut Ig, Demenais F, Strachan Dp, Bouzigon E, et al
The New England journal of medicine 2010;363(13):1211-1221

Assessment of the Neuropeptide S System in Anxiety Disorders
Donner J, Haapakoski R, Ezer S, Melen E, Pirkola S, Gratacos M, et al
BIOLOGICAL PSYCHIATRY 2010;68(5):474-83

Large-scale analysis of COL29A1 gene variation for eczema and related traits
Rodriguez E, Naumann A, Soderhall C, Foelster-holst R, Ruether A, Baurecht H, et al
JOURNAL OF INVESTIGATIVE DERMATOLOGY 2010;:S79-S79

Localization of psoriasis candidate gene product CCHCR1 at centrosomes
Tervaniemi M, Soderhall C, Siitonen A, Samuelsson L, Suomela S, Saarialho-kere U, et al
JOURNAL OF INVESTIGATIVE DERMATOLOGY 2010;:S81-S81

MMP-9,-10, and-26, and TIMP-1 expression in relation to filaggrin mutations in atopic dermatitis
Widen-karlsson V, Virolainen S, Soderhall C, Skoog T, Kero M, Kere J, et al
JOURNAL OF INVESTIGATIVE DERMATOLOGY 2010;:S19-S19

MMP12, Lung Function, and COPD in High-Risk Populations
Hunninghake Gm, Cho Mh, Tesfaigzi Y, Soto-quiros Me, Avila L, Lasky-su J, et al
NEW ENGLAND JOURNAL OF MEDICINE 2009;361(27):2599-608

No Association Between the Eczema Genes COL29Al and IL3l and Inflammatory Bowel Disease
Zucchelli M, Torkvist L, Bresso F, Halfvarson J, Soderhall C, Lee Ya, et al
INFLAMMATORY BOWEL DISEASES 2009;15(7):961-2

Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias
Beleza-meireles A, Tohonen V, Soderhall C, Schwentner C, Radmayr C, Kockum I, et al
EUROPEAN JOURNAL OF ENDOCRINOLOGY 2008;158(5):729-39

A new susceptibility locus for hypospadias on chromosome 7q32.2-q36.1
Thai Htt, Soderhall C, Lagerstedt K, Omrani Md, Frisen L, Lundin J, et al
HUMAN GENETICS 2008;124(2):155-60

Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
Marenholz I, Soderhall C, Kerscher T, Ruschendorf F, Esparza-gordillo J, Worm M, et al
ALLERGY 2008;:612-612

Risk factors for hypospadias in the estrogen receptor 2 gene
Beleza-meireles A, Kockum I, Lundberg F, Soderhall C, Nordenskjold A
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2007;92(9):3712-8

Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis
Soderhall C, Marenholz I, Kerscher T, Ruschendorf F, Esparza-gordillo J, Worm M, et al
PLOS BIOLOGY 2007;5(9):1952-1961

Genome-wide linkage analysis of allergic rhinoconjunctivitis in a Swedish population
Bu Lm, Bradley M, Soderhall C, Wahlgren Cf, Kockum I, Nordenskjold M
CLINICAL AND EXPERIMENTAL ALLERGY 2006;36(2):204-10

Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population
Bu Lm, Bradley M, Soderhall C, Wahlgren Cf, Kockum I, Nordenskjold M
ALLERGY 2006;61(5):617-21

Lack of association of the G protein-coupled receptor for asthma susceptibility gene with atopic dermatitis
Soderhall C, Marenholz I, Nickel R, Gruber C, Kehrt R, Rohde K, et al
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 2005;116(1):220-1

Genome-wide linkage analysis for hypospadias susceptibility genes
Frisen L, Soderhall C, Tapper-persson M, Luthman H, Kockum I, Nordenskjold A
JOURNAL OF UROLOGY 2004;172(4):1460-3

Analysis of association and linkage for the interleukin-4 and interleukin-4 receptor alpha; regions in Swedish atopic dermatitis families
Soderhall C, Bradley M, Kockum I, Luthman H, Wahlgren Cf, Nordenskjold M
CLINICAL AND EXPERIMENTAL ALLERGY 2002;32(8):1199-202

Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17 and 18 in a Swedish population
Bradley M, Soderhall C, Luthman H, Wahlgren Cf, Kockum I, Nordenskjold M
HUMAN MOLECULAR GENETICS 2002;11(13):1539-48

Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17, and 18 in a Swedish population.
Bradley M, Soderhall C, Luhtman H, Wahlgren Cf, Kockum I, Nordenskjold M
AMERICAN JOURNAL OF HUMAN GENETICS 2002;71(4):496-496

Linkage and association to candidate regions in Swedish atopic dermatitis families
Soderhall C, Bradley M, Kockum I, Wahlgren Cf, Luthman H, Nordenskjold M
HUMAN GENETICS 2001;109(2):129-35

Linkage to the Wiskott-Aldrich syndrome gene in Swedish patients with atopic dermatitis
Bradley M, Soderhall C, Wahlgren Cf, Luthman H, Nordenskjold M, Kockum I
JOURNAL OF INVESTIGATIVE DERMATOLOGY 2001;117(3):798-798

Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis
Ericson Kg, Fadeel B, Nilsson-ardnor S, Soderhall C, Samuelsson A, Janka G, et al
AMERICAN JOURNAL OF HUMAN GENETICS 2001;68(3):590-7

The Wiskott-Aldrich syndrome gene as a candidate gene for atopic dermatitis
Bradley M, Soderhall C, Wahlgren Cf, Luthman H, Nordenskjold M, Kockum I
ACTA DERMATO-VENEREOLOGICA 2001;81(5):340-2

Characterization by phenotype of families with atopic dermatitis
Bradley M, Kockum I, Soderhall C, Van Hage-hamsten M, Luthman H, Nordenskjold M, et al
ACTA DERMATO-VENEREOLOGICA 2000;80(2):106-10

Screening for mutations in candidate genes for hypospadias
Nordenskjold A, Friedman E, Tapper-persson M, Soderhall C, Leviav A, Svensson J, et al
UROLOGICAL RESEARCH 1999;27(1):49-55

Neuronal nitric oxide synthase, nNOS, is not linked to infantile hypertrophic pyloric stenosis in three families
Soderhall C, Nordenskjold A
CLINICAL GENETICS 1998;53(5):421-2

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