Chris Tibbitt

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(4):e2350660

Single-cell RNA sequencing of cells from fresh or frozen tissue reveals a signature of freezing marked by heightened stress and activation.

Stamper CT; Marchalot A; Tibbitt CA; Weigel W; Jangard M; Theorell J; Mjösberg J
Article: NATURE COMMUNICATIONS. 2024;15(1):683

Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity.

Dean I; Lee CYC; Tuong ZK; Li Z; Tibbitt CA; Willis C; Gaspal F; Kennedy BC; Matei-Rascu V; Fiancette R; Nordenvall C; Lindforss U; Baker SM; Stockmann C; Sexl V; Hammond SA; Dovedi SJ; Mjösberg J; Hepworth MR; Carlesso G; Clatworthy MR; Withers DR
Article: CELL REPORTS MEDICINE. 2023;4(5):101038

The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis.

Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Ideström M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjösberg J
Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2023;13(3):e12238

Obese asthma phenotypes display distinct plasma biomarker profiles.

Björkander S; Klevebro S; Hernandez-Pacheco N; Kere M; Ekström S; Sparreman Mikus M; van Hage M; James A; Kull I; Bergström A; Mjösberg J; Tibbitt CA; Melén E
Article: ISCIENCE. 2022;25(10):105137

PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype.

Wagner AK; Kadri N; Tibbitt C; van de Ven K; Bagawath-Singh S; Oliinyk D; LeGresley E; Campbell N; Trittel S; Riese P; Ribacke U; Sandalova T; Achour A; Kärre K; Chambers BJ
Article: ALLERGY. 2022;77(10):2987-3001

Recombinant multimeric dog allergen prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH 2 and TH 17 cell responses.

Stark JM; Liu J; Tibbitt CA; Christian M; Ma J; Wintersand A; Dunst J; Kreslavsky T; Murrell B; Adner M; Grönlund H; Gafvelin G; Coquet JM
Article: SCIENCE IMMUNOLOGY. 2022;7(70):eabj8301

CD45RA+CD62L- ILCs in human tissues represent a quiescent local reservoir for the generation of differentiated ILCs.

Kokkinou E; Pandey RV; Mazzurana L; Gutierrez-Perez I; Tibbitt CA; Weigel W; Soini T; Carrasco A; Rao A; Nagasawa M; Bal SM; Jangard M; Friberg D; Lindforss U; Nordenvall C; Ljunggren M; Haapaniemi S; Keita ÅV; Söderholm J; Hedin C; Spits H; Bryceson YT; Mjösberg J
Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267

Intestinal helminth infection transforms the CD4+ T cell composition of the skin.

Classon CH; Li M; Clavero AL; Ma J; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs AG; Eidsmo L; Coquet JM; Nylén S
Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabg6356

Single-cell analysis pinpoints distinct populations of cytotoxic CD4+ T cells and an IL-10+CD109+ TH2 cell population in nasal polyps.

Ma J; Tibbitt CA; Georén SK; Christian M; Murrell B; Cardell L-O; Bachert C; Coquet JM
Article: IMMUNOLOGY AND CELL BIOLOGY. 2021;99(2):234-243

GPR43 regulates marginal zone B-cell responses to foreign and endogenous antigens.

Rohrbeck L; Adori M; Wang S; He C; Tibbitt CA; Chernyshev M; Sirel M; Ribacke U; Murrell B; Bohlooly-Y M; Karlsson MC; Karlsson Hedestam GB; Coquet JM
Article: IMMUNITY INFLAMMATION AND DISEASE. 2020;8(1):8-23

PD-1 expression affects cytokine production by ILC2 and is influenced by peroxisome proliferator-activated receptor-γ.

Batyrova B; Luwaert F; Maravelia P; Miyabayashi Y; Vashist N; Stark JM; Soori SY; Tibbitt CA; Riese P; Coquet JM; Chambers BJ
Article: IMMUNITY. 2019;51(1):169-184.e5

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells.

Tibbitt CA; Stark JM; Martens L; Ma J; Mold JE; Deswarte K; Oliynyk G; Feng X; Lambrecht BN; De Bleser P; Nylén S; Hammad H; Arsenian Henriksson M; Saeys Y; Coquet JM
Article: JOURNAL OF AUTOIMMUNITY. 2019;98:86-94

Multi-faceted inhibition of dendritic cell function by CD4+Foxp3+ regulatory T cells.

Seitz C; Liu S; Klocke K; Joly A-L; Czarnewski PV; Tibbitt CA; Parigi SM; Westerberg LS; Coquet JM; Villablanca EJ; Wing K; Andersson J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(8):e145-e158

Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis.

Centa M; Prokopec KE; Garimella MG; Habir K; Hofste L; Stark JM; Dahdah A; Tibbitt CA; Polyzos KA; Gisterå A; Johansson DK; Maeda NN; Hansson GK; Ketelhuth DFJ; Coquet JM; Binder CJ; Karlsson MCI; Malin S
Article: SCIENCE IMMUNOLOGY. 2017;2(9):eaal5196

PPAR-γ promotes type 2 immune responses in allergy and nematode infection.

Chen T; Tibbitt CA; Feng X; Stark JM; Rohrbeck L; Rausch L; Sedimbi SK; Karlsson MCI; Lambrecht BN; Karlsson Hedestam GB; Hendriks RW; Chambers BJ; Nylén S; Coquet JM
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1633-1643

Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance.

Tibbitt C; Falconer J; Stoop J; van Eden W; Robinson JH; Hilkens CMU
Journal article: BIO-PROTOCOL. 2016;6(14)

House Dust Mite Extract and Cytokine Instillation of Mouse Airways and Subsequent Cellular Analysis

Tibbitt C; Coquet J
Article: IMMUNOLOGY. 2013;138(1):68-75

The choice of adjuvant determines the cytokine profile of T cells in proteoglycan-induced arthritis but does not influence disease severity.

Stoop JN; Tibbitt CA; van Eden W; Robinson JH; Hilkens CMU

Alla övriga publikationer

Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa4407

Peripheral innate lymphoid cell and T cell phenotypes are associated with treatable traits in young adults with asthma

Kere M; Bjorkander S; Tibbitt CA; Mjosberg J; Melen E
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:oa2502

Innate lymphoid cells type 2 and CD8+T cells are perturbed in overweight and obese individuals with asthma

Bjorkander S; Maier P; Kere M; Merid SK; Wirth L; Weigel W; Mjosberg J; Melen E; Tibbitt C
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:oa2495

Late Breaking Abstract - Dynamics of the blood innate lymphoid cell compartment in patients with severe asthma undergoing type 2 biologics treatment: Initial findings in the BIOCROSS study

Wirth L; Yasinska V; Tibbitt CA; Weigel W; Hochdorfer T; Andersson LI; Sparreman-Mikus M; Dahlen B; Dahlen S-E; Mjosberg J
Letter: ALLERGY. 2023;78(9):2533-2536

Innate lymphoid cells type 2 and CD8+ T cells are perturbed in overweight and obese individuals with asthma.

Björkander S; Maier P; Kere M; Merid SK; Wirth L; Wiegel W; Ekström S; Kull I; Bergström A; Melén E; Mjösberg J; Tibbitt CA
Preprint: 2023;bioRxiv

Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers

Dean I; Lee CYC; Tuong Z; Li Z; Tibbitt C; Willis C; Gaspal F; Kennedy B; Matei-Rascu V; Fiancette R; Nordenvall C; Lindforss U; Baker SM; Stockmann C; Sexl V; Carlesso G; Hammond S; Dovedi S; Mjösberg J; Hepworth M; Clatworthy M; Withers D
Editorial comment: ALLERGY. 2023;78(7):2061-2063

pH sensing shapes immune cell function: The role of GPR65 and its implications for allergic disease.

de Souza Ferreira S; Bek MK; Tibbitt CA
Review: CURRENT ALLERGY AND ASTHMA REPORTS. 2021;21(11):45

The Role of PPAR-γ in Allergic Disease.

Stark JM; Coquet JM; Tibbitt CA
Preprint: 2021;bioRxiv

Intestinal helminth infection transforms the CD4+ T cell composition of the skin

Classon CH; Li M; Ma J; Clavero L; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs G; Eidsmo L; Coquet JM; Nylén S
Preprint: 2021;bioRxiv

PD-1 expression on NK cells can be related to cytokine stimulation and tissue residency

Wagner A; Kadri N; Tibbitt C; van de Ven K; Bagawath-Singh S; Oliinyk D; LeGresly E; Campbell N; Trittel S; Riese P; Sandalova T; Achour A; Kärre K; Chambers B
Preprint: 2021;bioRxiv

Sublingual allergen immunotherapy with recombinant dog allergens prevents airway hyperresponsiveness in a model of asthma marked by vigorous T_H2 and T_H17 cell responses

Stark J; Liu J; Tibbitt C; Christian M; Ma J; Wintersand A; Murrell B; Adner M; Grönlund H; Gafvelin G; Coquet J
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:260

Nasal polyps are characterized by a population of CD109+CRTH2-Th2 cells that secrete interleukin-4 and interleukin-10

Ma J; Tibbitt CA; Georen SK; Georen SK; Christian M; Murrell B; Cardell LO; Cardell LO; Bachert C; Bachert C; Bachert C; Coquet JM
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)

Single-cell analysis pinpoints distinct populations of cytotoxic CD4 T cells and an IL-10+CD109+Th2 cell population in nasal polyps

Ma J; Tibbitt C; Georen S; Christian M; Murrell B; Cardell L; Bachert C; Coquet J
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2318

The Metabolic Requirements of Th2 Cell Differentiation.

Stark JM; Tibbitt CA; Coquet JM
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2019;49:403-404

Understanding the role of T helper cells during asthmatic inflammation

Stark JM; Tibbitt CA; Martens L; Ma J; Oliynyk G; Henriksson AM; Sayes Y; Coquet JM
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):275

Th2 cell metabolism

Stark JM; Tibbitt C; Oliynyk G; Henriksson MA; Coquet JM
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):250-251

Understanding the role T helper cells during asthmatic inflammation at the single cell level

Tibbitt C; Martens L; Saeys Y; Coquet J

Forskningsbidrag

Defining the metabolic signatures of tissue resident Innate Lymphoid Cells

Swedish Research Council

1 January 2021 - 31 December 2024

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