Carl-Fredrik Bowin

Artiklar

Article: NATURE COMMUNICATIONS. 2021;12(1):3919

Residue 6.43 defines receptor function in class F GPCRs.

Turku A; Schihada H; Kozielewicz P; Bowin C-F; Schulte G
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2021;4(3):1235-1245

Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments.

Kozielewicz P; Shekhani R; Moser S; Bowin C-F; Wesslowski J; Davidson G; Schulte G
Article: NATURE COMMUNICATIONS. 2020;11(1):414

Structural insight into small molecule action on Frizzleds.

Kozielewicz P; Turku A; Bowin C-F; Petersen J; Valnohova J; Cañizal MCA; Ono Y; Inoue A; Hoffmann C; Schulte G
Article: MOLECULAR PHARMACOLOGY. 2020;97(1):23-34

A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine.

Kozielewicz P; Bowin C-F; Turku A; Schulte G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(31):11677-11684

WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins.

Bowin C-F; Inoue A; Schulte G
Article: NATURE COMMUNICATIONS. 2019;10(1):667

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.

Wright SC; Kozielewicz P; Kowalski-Jahn M; Petersen J; Bowin C-F; Slodkowicz G; Marti-Solano M; Rodríguez D; Hot B; Okashah N; Strakova K; Valnohova J; Babu MM; Lambert NA; Carlsson J; Schulte G

Letter: CELL RESEARCH. 2021;31(12):1311-1314

Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs.

Xu L; Chen B; Schihada H; Wright SC; Turku A; Wu Y; Han G-W; Kowalski-Jahn M; Kozielewicz P; Bowin C-F; Zhang X; Li C; Bouvier M; Schulte G; Xu F
KI thesis / dissertation: 2021

WNT/Frizzled signaling : illuminating the road towards pathway selectivity

Bowin, Carl-Fredrik

Medicine Doktorsexamen, Institutionen för fysiologi och farmakologi, Karolinska Institutet, 2021