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Här listas aktuella publikationer i högt rankade vetenskapliga tidskrifter där forskare vid Institutionen för medicin, Huddinge medverkat.

Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Emgård J, Kammoun H, García-Cassani B, Chesné J, Parigi S, Jacob J, et al
Immunity 2018 Jan;48(1):120-132.e8

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.
Stone V, Hankaniemi M, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, et al
Diabetologia 2018 Feb;61(2):476-481

Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200R Monocyte-Derived Cells in Periodontitis.
Björnfot Holmström S, Clark R, Zwicker S, Bureik D, Kvedaraite E, Bernasconi E, et al
J. Immunol. 2017 12;199(12):4023-4035

Carrelha J, Meng Y, Kettyle LM, Luis TC, Norfo R, Alcolea V, Grasso F, Gambardella A, Grover A, Högstrand K, Lord AM, Sanjuan-Pla A, Woll PS, Nerlov C, Jacobsen SEW
Nature (2018) Online 3 January. Letter.

Länk till abstrakt i Nature


Dias J, Leeansyah E, Sandberg J

Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines.
Dias J, Leeansyah E, Sandberg J
Proc. Natl. Acad. Sci. U.S.A. 2017 07;114(27):E5434-E5443


Sandberg J, Norrby-Teglund A, Leeansyah E

Bacterial deception of MAIT cells in a cloud of superantigen and cytokines.
Sandberg J, Norrby-Teglund A, Leeansyah E
PLoS Biol. 2017 Jul;15(7):e2003167


Dias J, Sobkowiak M, Sandberg J, Leeansyah E, Center for Infectious Medicine

Human MAIT-cell responses to Escherichia coli: activation, cytokine production, proliferation, and cytotoxicity.
Dias J, Sobkowiak M, Sandberg J, Leeansyah E
J. Leukoc. Biol. 2016 07;100(1):233-40


Malin Flodström Tullberg, Center for Infectious Medicine

Enteroviral proteases: structure, host interactions and pathogenicity.
Laitinen O, Svedin E, Kapell S, Nurminen A, Hytönen V, Flodström-Tullberg M
Rev. Med. Virol. 2016 07;26(4):251-67


Malin Flodström Tullberg, Center for Infectious Medicine

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets.
Domsgen E, Lind K, Kong L, Hühn M, Rasool O, van Kuppeveld F, et al
Sci Rep 2016 12;6():39378


Rickard Sandberg, Integrated Cardio Metabolic Centre (ICMC), CMB 

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Segerstolpe , Palasantza A, Eliasson P, Andersson E, Andréasson A, Sun X, et al
Cell Metab. 2016 Oct;24(4):593-607


Soo Aleman, Enheten för inflammation, gastroenterologi och reumatologi 

Diabetes and Cirrhosis Are Risk Factors for Hepatocellular Carcinoma After Successful Treatment of Chronic Hepatitis C.
Hedenstierna M, Nangarhari A, Weiland O, Aleman S
Clin. Infect. Dis. 2016 Sep;63(6):723-9


Johan K. Sandberg, Edwin Leeansyah, Center for Infectious Medicine

Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.
Paquin-Proulx D, Gibbs A, Bächle S, Checa A, Introini A, Leeansyah E, et al
J. Immunol. 2016 09;197(5):1843-51


Johan K. Sandberg, Edwin Leeansyah, Center for Infectious Medicine

MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation.
Gibbs A, Leeansyah E, Introini A, Paquin-Proulx D, Hasselrot K, Andersson E, et al
Mucosal Immunol 2017 01;10(1):35-45


Mikael Rydén, Peter Arner, Enheten för endokrinologi och diabetes:

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity


Anders Sönnerborg, Enheten för infektionssjukdomar och hud:

Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.

Hofstra LM, Sauvageot N, Albert J, Alexiev I, Garcia F, Struck D, Van de Vijver DA, Åsjö B, Beshkov D, Coughlan S, Descamps D, Griskevicius A, Hamouda O, Horban A, Van Kasteren M, Kolupajeva T, Kostrikis LG, Liitsola K, Linka M, Mor O, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Staneková D, Stanojevic M, Van Laethem K, Zazzi M, Zidovec Lepej S, Boucher CA, Schmit JC, Wensing AM; SPREAD Program.

Clin Infect Dis. 2016 Mar 1;62(5):655-63. doi: 10.1093/cid/civ963. Epub 2015 Nov 29.


Jenny Mjösberg, Centrum för infektionsmedicin:

The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
Björklund , Forkel M, Picelli S, Konya V, Theorell J, Friberg D, et al
Nat. Immunol. 2016 Apr;17(4):451-60


Anders Sönnerborg, Amanda Häggblom, Enheten för infektionssjukdomar och hud:

Factors influencing the efficacy of rilpivirine in HIV-1 subtype C in low- and middle-income countries.
Neogi U, Häggblom A, Singh K, Rogers L, Rao S, Amogne W, et al
J. Antimicrob. Chemother. 2016 Feb;71(2):367-71


Anders Sönnerborg, Amanda Häggblom, Enheten för infektionssjukdomar och hud:

Häggblom A, Svedhem V, Singh K, Sönnerborg A, Neogi U. Viral failure in HIV-1 subtype C infected patients receiving anti-retroviral therapy in a national health care setting: A real-life prospective cohort study. Lancet HIV 2016.


Anders Sönnerborg, Enheten för infektionssjukdomar och hud:

Noguera-Julian M, Rocafort M, Guillén Y, Rivera J, Casadellà M, Nowak P, Hildebrand F, Zeller G, Parera M, Bellido R, Rodríguez C, Carrillo J, Mothe B, Coll J, Bravo I, Estany C, Herrero C, Saz J, Sirera G, Torrela A, Navarro J, Crespo M, Brander C, Negredo E, Blanco J, Guarner F, Luz Calle M, Bork P, Sönnerborg A, Clotet B, Paredes R. Gut microbiota linked to sexual practice and HIV infection. eBiomedicine 2016


Anders Sönnerborg, Enheten för infektionssjukdomar och hud:

Gupta R Sönnerborg A for the TenoRes collaboration. Global epidemiology of drug resistance following failure of WHO recommended first line regimens for adult HIV-1 infection – a multicenter retrospective cohort study. Lancet Infectious Diseases 2016,


Per Ljungman, Enheten för hematologi:

Stem cell transplantation in severe congenital neutropenia: an analysis from the European Society for Blood and Marrow Transplantation.
Fioredda F, Iacobelli S, van Biezen A, Gaspar B, Ancliff P, Donadieu J, et al
Blood 2015 Oct;126(16):1885-92; quiz 1970


Per Ljungman, Enheten för hematologi:

Immunogenicity, safety, and tolerability of 13-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal polysaccharide vaccine in recipients of allogeneic hematopoietic stem cell transplant aged ≥2 years: an open-label study.
Cordonnier C, Ljungman P, Juergens C, Maertens J, Selleslag D, Sundaraiyer V, et al
Clin. Infect. Dis. 2015 Aug;61(3):313-23


Hareth Nahi, Centrum för hematologi och regenerativ medicin:

Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma.
Lokhorst H, Plesner T, Laubach J, Nahi H, Gimsing P, Hansson M, et al
N. Engl. J. Med. 2015 Sep;373(13):1207-19


Mattias Svensson, Centrum för infektionsmedicin: 

Tissue-infiltrating neutrophils represent the main source of IL-23 in the colon of patients with IBD.
Kvedaraite E, Lourda M, Ideström M, Chen P, Olsson-Åkefeldt S, Forkel M, et al
Gut 2016 10;65(10):1632-41.


Susanna Brighenti och Jagadees Rao Muvva, Centrum för infektionsmedicin: 

Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages.
Rekha R, Rao Muvva S, Wan M, Raqib R, Bergman P, Brighenti S, et al
Autophagy 2015 ;11(9):1688-99.


Mikael Rydén, Peter Arner, Daniel P Andersson, Erik Arner, Yvonne Widlund, Niklas Mejhert, Enheten för endokrinologi och diabetes:

Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.
Rydén M, Uzunel M, Hård J, Borgström E, Mold J, Arner E, et al
Cell Metab. 2015 Sep;22(3):408-17


Hannes Hagström, Per Stål och Rolf Hultcrantz, Enheten för inflammation, gastroenterologi och reumatologi:

Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up.
Ekstedt M, Hagström H, Nasr P, Fredrikson M, Stål P, Kechagias S, et al
Hepatology 2015 May;61(5):1547-54


Dina Melki och Tomas Jernberg, Enheten för hjärt- och lungsjukdomar:

Implications of introducing high-sensitivity cardiac troponin T into clinical practice
Melki D, Lugnegård J, Alfredsson J, Lind S, Eggers KM, Lindahl B, Jernberg T.
J Am Coll Cardiology (2015) Online 20 April. Original investigation.

Hans-Gustaf Ljunggren och Yenan Bryceson, Centrum för infektionsmedicin:

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function
Schlums H, Cichocki F, Tesi B, Theorell J, Beziat V, Holmes TD, Han H, Chiang SCC, Foley B, Mattsson K, Larsson S, Schaffer M, Malmberg K-J, Ljunggren H-G, Miller JS, Bryceson YT.
Immunity (2015) Online 17 March. Article.


Karolina Szummer, Enheten för hjärt- och lungsjukdomar:

Association between the use of fondaparinux vs low-molecular-weight heparin and clinical outcomes in patients with non-ST-segment elevation myocardial infarction.
Szummer K, Oldgren J, Lindhagen L, Carrero J, Evans M, Spaak J, et al
JAMA 2015 Feb;313(7):707-16


Professor Johan Sandberg, Centrum för infektionsmedicin:

HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels.
Eller M, Opollo M, Liu M, Redd A, Eller L, Kityo C, et al
J. Infect. Dis. 2015 May;211(10):1574-84


Professor Anders Sönnerborg, Enheten för infektionssjukdomar och hud:

Occasional spontaneous clearance of chronic hepatitis C virus in HIV-infected individuals.
Stenkvist J, Nyström J, Falconer K, Sönnerborg A, Weiland O
J. Hepatol. 2014 Oct;61(4):957-61

Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients.
Neogi U, Rao S, Bontell I, Verheyen J, Rao V, Gore S, et al
AIDS 2014 Sep;28(15):2319-22


Professor Ola Weiland, Enheten för infektionssjukdomar och hud:

ABT-450, ritonavir, ombitasvir, and dasabuvir achieves 97% and 100% sustained virologic response with or without ribavirin in treatment-experienced patients with HCV genotype 1b infection.
Andreone P, Colombo M, Enejosa J, Koksal I, Ferenci P, Maieron A, et al
Gastroenterology 2014 Aug;147(2):359-365.e1

Patient-reported outcomes assessment in chronic hepatitis C treated with sofosbuvir and ribavirin: the VALENCE study.
Younossi Z, Stepanova M, Zeuzem S, Dusheiko G, Esteban R, Hezode C, et al
J. Hepatol. 2014 Aug;61(2):228-34