Our research
Our group has previously demonstrated that gut microbiota undergoes extensive changes during HIV infection, contributing to the chronic inflammation. We have also identified distinct microbiome signatures associated with antiretroviral therapy and shown, through in vitro experiments, that certain antiretrovirals exhibit antibacterial properties. Additionally, we have found that elite controllers — rare individuals capable of controlling HIV-1 infection without treatment — possess a gut microbiome like that of healthy individuals.
The primary goal of our research is to unravel the complex interplay between the microbiome and the immune system that underlies mechanisms of disease control and viral persistence. Our research is highly translational and patient-centered, applying cutting-edge multi-omics technologies to address clinically relevant questions.
Open positions
We always want to get in touch with talented potential co-workers. If you are interested in doing research within our group, as a degree project or as a researcher, please contact the group leader Piotr Nowak.
Research support
- Swedish Research Council
- Center of Innovative Medicine, Region Stockholm
- Swedish Physicians Against AIDS Foundation
- Region Stockholm
- Karolinska Institutet