Tobias Allanders grupp

Publikationer

Utvalda publikationer

Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(2):110-130
MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
Masso-Valles D; Beaulieu M-E; Jauset T; Giuntini F; Zacarias-Fluck MF; Foradada L; Martinez-Martin S; Serrano E; Martin-Fernandez G; Casacuberta-Serra S; Cano VC; Kaur J; Lopez-Estevez S; Morcillo MA; Alzrigat M; Mahmoud L; Luque-Garcia A; Escorihuela M; Guzman M; Arribas J; Serra V; Larsson L-G; Whitfield JR; Soucek L
Journal article: INVESTIGATIONAL NEW DRUGS. 2021;39(2):587-594
The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells
AlSultan D; Kavanagh E; O'Grady S; Eustace AJ; Castell A; Larsson L-G; Crown J; Madden SF; Duffy MJ
Article: CELL CYCLE. 2021;20(1):23-38
Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence
Bazzar W; Bocci M; Hejll E; Hogqvist Tabor V; Hydbring P; Grandien A; Alzrigat M; Larsson L-G
Article: METHODS IN MOLECULAR BIOLOGY. 2021;2318:241-254
Methods to Study Myc-Regulated Cellular Senescence: An Update.
Zhang F; Bazzar W; Alzrigat M; Larsson L-G
Article: ELIFE. 2020;9:e57894
PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer
Brunner A; Rahmanto AS; Johansson H; Franco M; Viiliainen J; Gazi M; Frings O; Fredlund E; Spruck C; Lehtio J; Rantala JK; Larsson L-G; Sangfelt O
Article: SCIENTIFIC REPORTS. 2018;8(1):10064
A selective high affinity MYC-binding compound inhibits MYC: MAX interaction and MYC-dependent tumor cell proliferation
Castell A; Yan Q; Fawkner K; Hydbring P; Zhang F; Verschut V; Franco M; Zakaria SM; Bazzar W; Goodwin J; Zinzalla G; Larsson L-G
Review: GENES. 2017;8(7):E174-174
MYC Modulation around the CDK2/p27/SKP2 Axis
Hydbring P; Castell A; Larsson L-G
Article: ONCOTARGET. 2016;7(3):2837-2854
Interferon-γ-induced p27^KIP1 binds to and targets MYC for proteasome-mediated degradation
Bahram F; Hydbring P; Tronnersjo S; Zakaria SM; Frings O; Fahlen S; Nilsson H; Goodwin J; von der Lehr N; Su Y; Luescher B; Castell A; Larsson L-G
Editorial comment: CANCER DISCOVERY. 2015;5(7):701-703
Targeting MYC Translation in Colorectal Cancer
Castell A; Larsson L-G
Article: CANCER RESEARCH. 2014;74(16):4222-4229
MYC Synergizes with Activated BRAF^V600E in Mouse Lung Tumor Development by Suppressing Senescence
Tabor V; Bocci M; Alikhani N; Kuiper R; Larsson L-G
Article: EMBO MOLECULAR MEDICINE. 2013;5(7):1067-1086
CDK-mediated activation of the SCF^FBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
Cepeda D; Ng H-F; Sharifi HR; Mahmoudi S; Soto Cerrato V; Fredlund E; Magnusson K; Nilsson H; Malyukova A; Rantala J; Klevebring D; Vinals F; Bhaskaran N; Zakaria SM; Rahmanto AS; Grotegut S; Nielsen ML; Szigyarto CA-K; Sun D; Lerner M; Navani S; Widschwendter M; Uhlen M; Jirstrom K; Ponten F; Wohlschlegel J; Grander D; Spruck C; Larsson L-G; Sangfelt O
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(4):E187-E196
The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
Menssen A; Hydbring P; Kapelle K; Vervoorts J; Diebold J; Luescher B; Larsson L-G; Hermeking H
Review: SEMINARS IN CANCER BIOLOGY. 2011;21(6):367-376
Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence
Larsson L-G
Review: CANCER RESEARCH. 2010;70(17):6687-6691
Tipping the Balance: Cdk2 Enables Myc to Suppress Senescence
Hydbring P; Larsson L-G
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1429-1437
The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy
Larsson L-G; Henriksson MA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(1):58-63
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation
Hydbring P; Bahram F; Su Y; Tronnersjo S; Hogstrand K; von der Lehr N; Sharifi HR; Lilischkis R; Hein N; Wu S; Vervoorts J; Henriksson M; Grandien A; Luscher B; Larsson L-G
Article: NATURE CELL BIOLOGY. 2010;12(1):54-59
Cdk2 suppresses cellular senescence induced by the c-myc oncogene
Campaner S; Doni M; Hydbring P; Verrecchia A; Bianchi L; Sardella D; Schleker T; Perna D; Tronnersjo S; Murga M; Fernandez-Capetillo O; Barbacid M; Larsson L-G; Amati B
Article: NATURE METHODS. 2006;3(12):995-1000
Direct observation of individual endogenous protein complexes in situ by proximity ligation.
Söderberg O; Gullberg M; Jarvius M; Ridderstråle K; Leuchowius K-J; Jarvius J; Wester K; Hydbring P; Bahram F; Larsson L-G; Landegren U
Article: NATURE CELL BIOLOGY. 2005;7(3):303-310
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
Arabi A; Wu SQ; Ridderstråle K; Bierhoff H; Shiue C; Fatyol K; Fahlén S; Hydbring P; Söderberg O; Grummt I; Larsson LG; Wright APH
Article: MOLECULAR CELL. 2003;11(5):1189-1200
The F-Box protein Skp2 participates in c-Myc protelosornal degradation and acts as a cofactor for c-Myc-regulated transcription
von der Lehr N; Johansson S; Wu SQ; Bahram F; Castell A; Cetinkaya C; Hydbring P; Weidung I; Nakayama K; Nakayama KI; Söderberg O; Kerppola TK; Larsson LG
Article: BLOOD. 2000;95(6):2104-2110
c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover.
Bahram F; von der Lehr N; Cetinkaya C; Larsson LG
Visa fler

Tobias Allanders grupp

Publikationer

Utvalda publikationer

Medarbetare och kontakt

Gruppledare

Alla medarbetare i gruppen