Tobias Allanders grupp

Publikationer

Utvalda publikationer

• Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(2):110-130

  MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

  Masso-Valles D; Beaulieu M-E; Jauset T; Giuntini F; Zacarias-Fluck MF; Foradada L; Martinez-Martin S; Serrano E; Martin-Fernandez G; Casacuberta-Serra S; Cano VC; Kaur J; Lopez-Estevez S; Morcillo MA; Alzrigat M; Mahmoud L; Luque-Garcia A; Escorihuela M; Guzman M; Arribas J; Serra V; Larsson L-G; Whitfield JR; Soucek L
• Journal article: INVESTIGATIONAL NEW DRUGS. 2021;39(2):587-594

  The novel low molecular weight MYC antagonist MYCMI-6 inhibits proliferation and induces apoptosis in breast cancer cells

  AlSultan D; Kavanagh E; O'Grady S; Eustace AJ; Castell A; Larsson L-G; Crown J; Madden SF; Duffy MJ
• Article: CELL CYCLE. 2021;20(1):23-38

  Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence

  Bazzar W; Bocci M; Hejll E; Hogqvist Tabor V; Hydbring P; Grandien A; Alzrigat M; Larsson L-G
• Article: METHODS IN MOLECULAR BIOLOGY. 2021;2318:241-254

  Methods to Study Myc-Regulated Cellular Senescence: An Update.

  Zhang F; Bazzar W; Alzrigat M; Larsson L-G
• Article: ELIFE. 2020;9:e57894

  PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer

  Brunner A; Rahmanto AS; Johansson H; Franco M; Viiliainen J; Gazi M; Frings O; Fredlund E; Spruck C; Lehtio J; Rantala JK; Larsson L-G; Sangfelt O
• Article: SCIENTIFIC REPORTS. 2018;8(1):10064

  A selective high affinity MYC-binding compound inhibits MYC: MAX interaction and MYC-dependent tumor cell proliferation

  Castell A; Yan Q; Fawkner K; Hydbring P; Zhang F; Verschut V; Franco M; Zakaria SM; Bazzar W; Goodwin J; Zinzalla G; Larsson L-G
• Review: GENES. 2017;8(7):E174-174

  MYC Modulation around the CDK2/p27/SKP2 Axis

  Hydbring P; Castell A; Larsson L-G
• Article: ONCOTARGET. 2016;7(3):2837-2854

  Interferon-γ-induced p27^KIP1 binds to and targets MYC for proteasome-mediated degradation

  Bahram F; Hydbring P; Tronnersjo S; Zakaria SM; Frings O; Fahlen S; Nilsson H; Goodwin J; von der Lehr N; Su Y; Luescher B; Castell A; Larsson L-G
• Editorial comment: CANCER DISCOVERY. 2015;5(7):701-703

  Targeting MYC Translation in Colorectal Cancer

  Castell A; Larsson L-G
• Article: CANCER RESEARCH. 2014;74(16):4222-4229

  MYC Synergizes with Activated BRAF^V600E in Mouse Lung Tumor Development by Suppressing Senescence

  Tabor V; Bocci M; Alikhani N; Kuiper R; Larsson L-G
• Article: EMBO MOLECULAR MEDICINE. 2013;5(7):1067-1086

  CDK-mediated activation of the SCF^FBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

  Cepeda D; Ng H-F; Sharifi HR; Mahmoudi S; Soto Cerrato V; Fredlund E; Magnusson K; Nilsson H; Malyukova A; Rantala J; Klevebring D; Vinals F; Bhaskaran N; Zakaria SM; Rahmanto AS; Grotegut S; Nielsen ML; Szigyarto CA-K; Sun D; Lerner M; Navani S; Widschwendter M; Uhlen M; Jirstrom K; Ponten F; Wohlschlegel J; Grander D; Spruck C; Larsson L-G; Sangfelt O
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(4):E187-E196

  The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

  Menssen A; Hydbring P; Kapelle K; Vervoorts J; Diebold J; Luescher B; Larsson L-G; Hermeking H
• Review: SEMINARS IN CANCER BIOLOGY. 2011;21(6):367-376

  Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence

  Larsson L-G
• Review: CANCER RESEARCH. 2010;70(17):6687-6691

  Tipping the Balance: Cdk2 Enables Myc to Suppress Senescence

  Hydbring P; Larsson L-G
• Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1429-1437

  The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

  Larsson L-G; Henriksson MA
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(1):58-63

  Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

  Hydbring P; Bahram F; Su Y; Tronnersjo S; Hogstrand K; von der Lehr N; Sharifi HR; Lilischkis R; Hein N; Wu S; Vervoorts J; Henriksson M; Grandien A; Luscher B; Larsson L-G
• Article: NATURE CELL BIOLOGY. 2010;12(1):54-59

  Cdk2 suppresses cellular senescence induced by the c-myc oncogene

  Campaner S; Doni M; Hydbring P; Verrecchia A; Bianchi L; Sardella D; Schleker T; Perna D; Tronnersjo S; Murga M; Fernandez-Capetillo O; Barbacid M; Larsson L-G; Amati B
• Article: NATURE METHODS. 2006;3(12):995-1000

  Direct observation of individual endogenous protein complexes in situ by proximity ligation.

  Söderberg O; Gullberg M; Jarvius M; Ridderstråle K; Leuchowius K-J; Jarvius J; Wester K; Hydbring P; Bahram F; Larsson L-G; Landegren U
• Article: NATURE CELL BIOLOGY. 2005;7(3):303-310

  c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription

  Arabi A; Wu SQ; Ridderstråle K; Bierhoff H; Shiue C; Fatyol K; Fahlén S; Hydbring P; Söderberg O; Grummt I; Larsson LG; Wright APH
• Article: MOLECULAR CELL. 2003;11(5):1189-1200

  The F-Box protein Skp2 participates in c-Myc protelosornal degradation and acts as a cofactor for c-Myc-regulated transcription

  von der Lehr N; Johansson S; Wu SQ; Bahram F; Castell A; Cetinkaya C; Hydbring P; Weidung I; Nakayama K; Nakayama KI; Söderberg O; Kerppola TK; Larsson LG
• Article: BLOOD. 2000;95(6):2104-2110

  c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover.

  Bahram F; von der Lehr N; Cetinkaya C; Larsson LG
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Medarbetare och kontakt

Gruppledare

• 

  Tobias Allander

  Adjungerad Lektor | Docent

  E-postadress tobias.allander@ki.se

Alla medarbetare i gruppen

• 

  Tobias Allander

  Adjungerad Lektor | Docent

  E-postadress tobias.allander@ki.se
• Amanj Bajalan

  Doktorand

  E-postadress amanj.bajalan@ki.se
• Claudia Beck Eichler Jonsson

  E-postadress claudia.beck.eichler.jonsson@ki.se
• Mirko Conti

  Anknuten till Forskning

  E-postadress mirko.conti@ki.se