The Small Molecule Mass Spectrometry Core Facility (KI-SMMS) - our offer

KI-SMMS provides an array of sensitive and specific methods to quantify small molecules in all types of sources. Our main goal is the generation of high-quality mass-spectrometry based data that fulfils the specific needs of each user. To that end, we can assist you with all parts of the pipeline, from experimental design to data interpretation.

The Small Molecule Mass Spectrometry Core Facility (KI-SMMS) offers services to analyse small molecules using the most specific and sensitive targeted mass spectrometry-based methods available.

Our services include broad metabolomics and lipidomics screening panels for the relative quantification of these small molecules.

We also provide full quantitation for selected panels including polar metabolites and lipids, as well as for xenobiotics like drugs, vitamins, and their biotransformation products.

Custom methods can also be developed on request.

We have decades-long cumulative experience servicing both academic and industrial projects. Whatever your question is, we make sure that the analyses are tailored to answer it. We focus on helping researchers by conducting metabolomic, lipidomic and other mass spectrometry-based experiments and analyses.

Our activity is focused on:

  • Supply researchers with the tools and resources they need to explore and understand biological phenomena at the small molecule level
  • Develop, adapt and establish novel approaches that anticipate future needs of researchers
  • Transversal technological research with other internal or external teams (platforms, research units)
  • Teaching and training users about the basics and possibilities that mass spectrometry offers in small molecule analysis

Let us make you an offer

Not sure what you want, how to do it or how much it will cost? Please contact us, schedule a meeting and/or book our services in iLab.

Our services


  • Waters Xevo TQ-S + Waters UPLC H-Class
  • Waters Xevo TQ-S u + Waters UPLC Premier
  • Waters Xevo TQ-XS + Waters UPLC Premier
  • Waters Xevo TQ-XS + Waters SFC
  • Waters Xevo-TQ Absolute + Waters UPLC i-Class

Our process

Both the analyses of a few metabolites or the profiling of hundreds of lipids require a proper experimental design to ensure that the results are of enough quality to answer your biological question.

We can assist in the planning, as well as in all the different steps of the process.

Process from initial contact to results.
The Small Molecule Mass Spectrometry Core Facility process.

Our pricing model

Our services are billed according to a fee-for-service basis, in accordance with Karolinska Insitute policies for core facilities.

The user fees for Swedish academic institutions are based on cost for consumables, university OH, and part of the cost for staff, instrumentation and rent.

Fees for academics outside Sweden include full cost for staff, instrumentation and rent.

Commercial users pay full costs including staff, premises, consumables and an added 50% margin.

Please log-in to iLab to see current pricing

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