X-ray Irradiation Core Facility (nodes ANA Futura & Biomedicum) - our offer
Our X-ray Irradiation Core Facility includes nodes in ANA Futura and Biomedicum, which are equipped with Xstrahl CIX2 X-ray machines for irradiation of biological material. The core facility is open for researchers at KI as well as for external users.
Irradiation of biological material using an X-ray machine
The primary use of the irradiators is to irradiate cultured cells suspended in cell culture medium in 15 ml and/or 50 ml centrifugation tubes or growing in tissue culture vessels as a mono-layer in sizes up to 175 square-centimeter cell culture bottles or different type of multiwell plates i.e. 6-well up to 384-well plates.
Equipment
X-ray irradiators for cells
Two CIX2 X-ray cabinets from Xstrahl have been acquired, one located in Biomedicum on Campus Solna and the other in ANA Futura on Campus Flemingsberg. These are 220kV self-contained cabinet irradiators.
SmART-RAD dosimetry software
Dose calculation software for Non-Image Guided Irradiatiors.
Features
- User-friendly interface which does not require dosimetry expertise
- Fully customizable Monte Carlo 3D dose calculation
- material composition of the specimen, geometric setup, shielding or fixation material, field size, energy spectrum, source to axis distance, backscatter material
- Customizable geometries such as shielding, added tumors, well plates, mouse pies, applicators
- Advanced dose display and analysis tools
- Publication-grade graphics
- Dose calculations can be completed in advance, during or after treatment
- Runs on standalone computer
- Automated calculations improve workflow, accuracy and reproducibility
- Standardized reporting following published guidelines”