X-ray Irradiation Core Facility (nodes ANA Futura & Biomedicum) - our offer

Our X-ray Irradiation Core Facility includes nodes in ANA Futura and Biomedicum, which are equipped with Xstrahl CIX2 X-ray machines for irradiation of biological material. The core facility is open for researchers at KI as well as for external users.

Irradiation of biological material using an X-ray machine

The primary use of the irradiators is to irradiate cultured cells suspended in cell culture medium in 15 ml and/or 50 ml centrifugation tubes or growing in tissue culture vessels as a mono-layer in sizes up to 175 square-centimeter cell culture bottles or different type of multiwell plates i.e. 6-well up to 384-well plates.

Equipment

X-ray irradiators for cells

Two CIX2 X-ray cabinets from Xstrahl have been acquired, one located in Biomedicum on Campus Solna and the other in ANA Futura on Campus Flemingsberg. These are 220kV self-contained cabinet irradiators.

Picture of the core faility CIX2 Xstrahl X-ray irradiator in Biomedicum
CIX2 Xstrahl X-ray irradiator in Biomedicum. Photo: Adamantia Fragkopoulou
Photo of X-ray equipment, core facility X-ray, Campus Flemingsberg, ANA Futura.
X-ray equipment, core facility X-ray, Campus Flemingsberg, ANA Futura. Photo: Lars Frelin

SmART-RAD dosimetry software

Dose calculation software for Non-Image Guided Irradiatiors.

Features

  • User-friendly interface which does not require dosimetry expertise
  • Fully customizable Monte Carlo 3D dose calculation
    • material composition of the specimen, geometric setup, shielding or fixation material, field size, energy spectrum, source to axis distance, backscatter material
  • Customizable geometries such as shielding, added tumors, well plates, mouse pies, applicators
  • Advanced dose display and analysis tools
  • Publication-grade graphics
  • Dose calculations can be completed in advance, during or after treatment
  • Runs on standalone computer
  • Automated calculations improve workflow, accuracy and reproducibility
  • Standardized reporting following published guidelines”

SmART-RAD in X-Ray Irradiation Core Facility, nodes ANA Futura and Biomedicum

Software used in core X-ray facility by Adamantia Fragkopoulou
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