SICOF - Recent user publications

Recent user publications 

2024

Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts.
Uhrbom M, Muhl L, Genové G, Liu J, Palmgren H, Alexandersson I, Karlsson F, Zhou AX, Lunnerdal S, Gustafsson S, Buyandelger B, Petkevicius K, Ahlstedt I, Karlsson D, Aasehaug L, He L, Jeansson M, Betsholtz C, Peng XR
Nat Commun 2024 Sep;15(1):7643

Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis.
Mocci G, Sukhavasi K, Örd T, Bankier S, Singha P, Arasu UT, Agbabiaje OO, Mäkinen P, Ma L, Hodonsky CJ, Aherrahrou R, Muhl L, Liu J, Gustafsson S, Byandelger B, Wang Y, Koplev S, Lendahl U, Owens GK, Leeper NJ, Pasterkamp G, Vanlandewijck M, Michoel T, Ruusalepp A, Hao K, Ylä-Herttuala S, Väli M, Järve H, Mokry M, Civelek M, Miller CJ, Kovacic JC, Kaikkonen MU, Betsholtz C, Björkegren JLM
Circ Res 2024 May;134(11):1405-1423

2023

Molecular anatomy of adult mouse leptomeninges.
Pietilä R, Del Gaudio F, He L, Vázquez-Liébanas E, Vanlandewijck M, Muhl L, Mocci G, Bjørnholm KD, Lindblad C, Fletcher-Sandersjöö A, Svensson M, Thelin EP, Liu J, van Voorden AJ, Torres M, Antila S, Xin L, Karlström H, Storm-Mathisen J, Bergersen LH, Moggio A, Hansson EM, Ulvmar MH, Nilsson P, Mäkinen T, Andaloussi Mäe M, Alitalo K, Proulx ST, Engelhardt B, McDonald DM, Lendahl U, Andrae J, Betsholtz C
Neuron 2023 Dec;111(23):3745-3764.e7

Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart.
Del Gaudio F, Liu D, Andaloussi Mäe M, Braune EB, Hansson EM, Wang QD, Betsholtz C, Lendahl U
Sci Rep 2023 Sep;13(1):15022

A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature.
Bjørnholm KD, Del Gaudio F, Li H, Li W, Vazquez-Liebanas E, Mäe MA, Lendahl U, Betsholtz C, Nilsson P, Karlström H, Vanlandewijck M
Cell Rep Methods 2023 Mar;3(3):100431

2022

A single-cell transcriptomic inventory of murine smooth muscle cells.
Lars Muhl, Giuseppe Mocci, Riikka Pietilä, Jianping Liu, Liqun He, Guillem Genové, Stefanos Leptidis, Sonja Gustafsson, Byambajav Buyandelger, Elisabeth Raschperger, Emil M. Hansson, Johan L.M. Björkegren, Michael Vanlandewijck, Urban Lendahl & Christer Betsholtz.  Developmental Cell, 57(20), 24 October 2022, Pages 2426-2443.e6. doi: 10.1016/j.devcel.2022.09.015.

KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling.
Ando K, Tong L, Peng D, Vázquez-Liébanas E, Chiyoda H, He L, Liu J, Kawakami K, Mochizuki N, Fukuhara S, Grutzendler J, Betsholtz C
Dev Cell 2022 Jun;57(11):1383-1399.e7. doi.org/10.1016/j.devcel.2022.04.019  

ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels.
Bernier-Latmani J, Mauri C, Marcone R, Renevey F, Durot S, He L, Vanlandewijck M, Maclachlan C, Davanture S, Zamboni N, Knott GW, Luther SA, Betsholtz C, Delorenzi M, Brisken C, Petrova TV
Nat Commun 2022 Jul;13(1):3983

The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research.
Muhl L, He L, Sun Y, Andaloussi Mäe M, Pietilä R, Liu J, Genové G, Zhang L, Xie Y, Leptidis S, Mocci G, Stritt S, Osman A, Anisimov A, Hemanthakumar KA, Räsänen M, Hansson EM, Björkegren J, Vanlandewijck M, Blomgren K, Mäkinen T, Peng XR, Hu Y, Ernfors P, Arnold TD, Alitalo K, Lendahl U, Betsholtz C
Stem Cell Reports 2022 05;17(5):1089-1104. doi.org/10.1016/j.stemcr.2022.03.016

CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells.
Somuncular E, Hauenstein J, Khalkar P, Johansson AS, Dumral Ö, Frengen NS, Gustafsson C, Mocci G, Su TY, Brouwer H, Trautmann CL, Vanlandewijck M, Orkin SH, Månsson R, Luc S
Stem Cell Reports 2022 Jul;17(7):1546-1560

2021

A human cell type similar to murine central nervous system perivascular fibroblasts-like cells.
Liu J, He L, Muhl L, Mocci G, Gustavsson S, Buyandelger B, Vanlandewijck M, Betsholtz C, Westermark B, Andrae J
Exp Cell Res 2021 05;402(2):112576. doi.org/10.1016/j.yexcr.2021.112576

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes.
He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Möller-Hackbarth K, Unnersjö-Jess D, Korkut GG, Charrin E, Jeansson M, Bintanel-Morcillo M, Witasp A, Wennberg L, Wernerson A, Schermer B, Benzing T, Ernfors P, Betsholtz C, Lal M, Sandberg R, Patrakka J
Nat Commun 2021 04;12(1):2141. doi.org/10.1038/s41467-021-22331-9

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss.
Mäe MA, He L, Nordling S, Vazquez-Liebanas E, Nahar K, Jung B, Li X, Tan BC, Chin Foo J, Cazenave-Gassiot A, Wenk MR, Zarb Y, Lavina B, Quaggin SE, Jeansson M, Gu C, Silver DL, Vanlandewijck M, Butcher EC, Keller A, Betsholtz C
Circ Res 2021 02;128(4):e46-e62. doi.org/10.1161/CIRCRESAHA.120.317473

2020

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination.
Muhl L, Genové G, Leptidis S, Liu J, He L, Mocci G, Sun Y, Gustafsson S, Buyandelger B, Chivukula IV, Segerstolpe Å, Raschperger E, Hansson EM, Björkegren JLM, Peng XR, Vanlandewijck M, Lendahl U, Betsholtz C. Nat Commun 2020 08;11(1):3953. doi.org/10.1038/s41467-020-17740-1

Single-cell RNA counting at allele and isoform resolution using Smart-seq3.
Hagemann-Jensen M, Ziegenhain C, Chen P, Ramsköld D, Hendriks GJ, Larsson AJM, Faridani OR, Sandberg R
Nat Biotechnol 2020 06;38(6):708-714. doi.org/10.1038/s41587-020-0497-0

DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes.
Sen I, Zhou X, Chernobrovkin A, Puerta-Cavanzo N, Kanno T, Salignon J, Stoehr A, Lin XX, Baskaner B, Brandenburg S, Björkegren C, Zubarev RA, Riedel CG
Nat Commun 2020 01;11(1):138. doi.org/10.1038/s41467-019-13931-7

2019

Adipose lipid turnover and long-term changes in body weight.
Arner P, Bernard S, Appelsved L, Fu KY, Andersson DP, Salehpour M, Thorell A, Rydén M, Spalding KL
Nat Med 2019 09;25(9):1385-1389. doi.org/10.1038/s41591-019-0565-5