Experimental Orthopedics
The research in the "Experimental Orthopedics" team aims to increase knowledge about the functional and biomechanical consequences of joint injuries, joint diseases, and skeletal deformities in children and adults.
Central to the research are various methods for evaluating joint mobility, joint and foot loading, and their connection to perceived pain and biomarkers in blood. Furthermore, we aim to investigate their significance for disease progression, treatment selection, and outcomes of administered treatments.
BIOFUNC – Studies focusing on osteoarthritis development and the link between knee function and blood biomarkers.
In individuals with established knee osteoarthritis, we have found associations between substances in the blood and the progression of knee function and pain over time. An anterior cruciate ligament (ACL) rupture is a common knee injury among athletes, and nearly half will develop knee osteoarthritis later in life. Surgical ACL reconstruction has not been shown to reduce the risk of osteoarthritis, and currently, there is no way to predict who will develop knee osteoarthritis.
The ongoing BIOFUNC project evaluates knee function, perceived symptoms, and blood substances in individuals with established osteoarthritis and those who have undergone ACL reconstruction, who thereby have an increased risk of developing osteoarthritis. The goal is to identify methods to predict osteoarthritis development.
Recurrent foot deformity in children with clubfoot
The project aims to evaluate standardized follow-up for children with clubfoot (congenital talipes equinovarus) to identify the best methods for detecting recurrence (return of foot deformity). The methods include examining ankle range of motion, dynamic foot loading during walking (pedobarography), clinical assessment tools, and video observation of children walking. Can we predict the risk of recurrence in children with clubfoot?
Team leader
Josefine Eriksson Naili, PhD, Associate professor of physiotherapy
Team members
Karol Gawelowicz, MD, PhD student
Åsa Thelaus, MD, PhD Student
Affiliated Researchers
Anders Holsgaard-Larsen, Professor of Biomechanics, University of Southern Denmark
Morten Bilde Simonsen, Postdoctoral Researcher, Aalborg University
The BIOFUNC project is conducted in close collaboration with
Cecilia Aulin, Associate professor of Immunology, CMM