Osman Ahmed

Publications
Grants
CV
Public outreach and news

Articles

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14):e2212476120
Cholinergic regulation of vascular endothelial function by human ChAT⁺ T cells
Tarnawski L; Shavva VS; Kort EJ; Zhuge Z; Nilsson I; Gallina AL; Martinez-Enguita D; Sahlgren BH; Weiland M; Caravaca AS; Schmidt S; Chen P; Abbas K; Wang F-H; Ahmed O; Eberhardson M; Farnert A; Weitzberg E; Gustafsson M; Kehr J; Malin SG; Hult H; Carlstrom M; Jovinge S; Olofsson PS
Article: BIOELECTRONIC MEDICINE. 2023;9(1):6
Hepatic stellate cell activation markers are regulated by the vagus nerve in systemic inflammation.
Ahmed O; Caravaca AS; Crespo M; Dai W; Liu T; Guo Q; Leiva M; Sabio G; Shavva VS; Malin SG; Olofsson PS
Journal article: ATHEROSCLEROSIS. 2022;355:20
Validation of network medicine interactomes: From patients to a human hepatocyte-like model
Grassi F; Dall'Olio D; Ahmed O; Sala C; Bersanelli M; Pramfalk C; Garagnani P; Petrillo E; Loscalzo J; Pedrelli M; Parini P
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):296-307
Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice
Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Hardfeldt J; Vedin L-L; Steffensen KR; Ryden M; Hodson L; Eriksson M; Parini P
Journal article: CIRCULATION. 2021;144(Suppl_1):a10013
Abstract 10013: PRDs Are Multifunctional Oral Inhibitors of PCSK9 and ACAT2
Paolo P; Ahmed O; Pedrelli M; Oshiro T; Pramfalk C; Eriksson M; Mejia E
Article: METHODS IN MOLECULAR BIOLOGY. 2020;2164:101-108
Enzymatic Quantification of Liver Lipids After Folch Extraction.
Minniti ME; Ahmed O; Pedrelli M
Article: DIGESTIVE AND LIVER DISEASE. 2019;51(7):1016-1022
Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice
Ahmed O; Pramfalk C; Pedrelli M; Olin M; Steffensen KR; Eriksson M; Parini P
Article: NATURE COMMUNICATIONS. 2019;10(1):1684
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα
Liang N; Damdimopoulos A; Goni S; Huang Z; Vedin L-L; Jakobsson T; Giudici M; Ahmed O; Pedrelli M; Barilla S; Alzaid F; Mendoza A; Schroder T; Kuiper R; Parini P; Hollenberg A; Lefebvre P; Francque S; Van Gaal L; Staels B; Venteclef N; Treuter E; Fan R
Article: BIOLOGY OF SEX DIFFERENCES. 2019;10(1):11
Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse
Gonzalez-Granillo M; Helguero LA; Alves E; Archer A; Savva C; Pedrelli M; Ahmed O; Li X; Domingues MR; Parini P; Gustafsson J-A; Korach-Andre M
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2018;7(24):e009876
Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients
Ahmed O; Littmann K; Gustafsson U; Pramfalk C; Oorni K; Larsson L; Minniti ME; Sahlin S; Camejo G; Parini P; Eriksson M
Article: ATHEROSCLEROSIS. 2018;275:246-255
Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption
Parini P; Melhuish TA; Wotton D; Larsson L; Ahmed O; Eriksson M; Pramfalk C
Article: PLOS NEGLECTED TROPICAL DISEASES. 2014;8(10):e3273
IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test
Bhattacharyya T; Ayandeh A; Falconar AK; Sundar S; El-Safi S; Gripenberg MA; Bowes DE; Thunissen C; Singh OP; Kumar R; Ahmed O; Eisa O; Saad A; Pereira SS; Boelaert M; Mertens P; Miles MA
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2014;306(5):E494-E502
Skeletal muscle as a target of LXR agonist after long-term treatment: focus on lipid homeostasis
Archer A; Laurencikiene J; Ahmed O; Steffensen KR; Parini P; Gustafsson J-A; Korach-Andre M
Article: PLOS NEGLECTED TROPICAL DISEASES. 2014;8(2):e2675
Significantly Lower Anti-Leishmania IgG Responses in Sudanese versus Indian Visceral Leishmaniasis
Bhattacharyya T; Bowes DE; El-Safi S; Sundar S; Falconar AK; Singh OP; Kumar R; Ahmed O; Boelaert M; Miles MA
Article: PLOS NEGLECTED TROPICAL DISEASES. 2010;4(8):e776
Diagnostic Accuracy of the Leishmania OligoC-TesT and NASBA-Oligochromatography for Diagnosis of Leishmaniasis in Sudan
Saad AA; Ahmed NG; Osman OS; Al-Basheer AA; Hamad A; Deborggraeve S; Buescher P; Schoone GJ; Schallig HD; Laurent T; Haleem A; Osman OF; Eltom AM; Elbashir MI; El-Safi S

All other publications

Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:s756-s757
Statins regulate PNPLA3 through a mechanism that requires SREBF2 in human liver cells
Ahmed O; Shavva VS; Dai W; Tarnawski L; Malin S; Franco-Cereceda A; Eriksson P; Bjorck H; Olofsson P
Preprint: BIORXIV. 2022
Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult
Hellberg S; Ahmed O; Zhang Y; Di Nunzio G; Björck HM; Francis R; Fagerberg L; Gisterå A; Zhang X; Metso J; Manfé V; Soto Y; Franco-Cereceda A; Eriksson P; Jauhiainen M; Olofsson PS; Malin SG
Conference publication: ATHEROSCLEROSIS. 2022;355:E51
VALIDATION OF NETWORK MEDICINE INTERACTOMES: FROM PATIENTS TO A HUMAN HEPATOCYTE-LIKE MODEL
Grassi F; Dall'Olio D; Ahmed O; Sala C; Bersanelli M; Pramfalk C; Garagnani P; Petrillo E; Loscalzo J; Pedrelli M; Parini P
Conference publication: ATHEROSCLEROSIS. 2021;331:E143-E144
HEPATIC TRANSCRIPTIONAL EFFECTS OF SIMVASTATIN AND THE POSSIBLE IMPACT ON COVID-19
Ahmed O; Mukarram AK; Pirazzini C; Marasco EE; Pedrelli M; Minniti ME; Gustafsson U; Pramfalk C; Binder CJ; Petrillo E; Garagnani PP; Daub CO; Eriksson M; Parini P
Thesis / dissertation: 2019
Role of cholesterol metabolism in hepatic steatosis and glucose tolerance
Ahmed, Osman Salih Osman
Meeting abstract: ATHEROSCLEROSIS. 2018;275:E234
SIMVASTATIN AND EZETIMIBE REDUCE PLASMA LIPOPROTEIN BINDING TO HUMAN ARTERIAL PROTEOGLYCANS IN GALLSTONE DISEASED PATIENTS
Littmann K; Ahmed O; Gustafsson U; Pramfalk C; Oorni K; Larsson L; Sahlin S; Camejo G; Parini P; Eriksson M
Meeting abstract: ATHEROSCLEROSIS. 2018;275:E25
GENETIC DEPLETION OF THE SOAT2 GENE DIMINISHES DIET-INDUCED HEPATIC STEATOSIS AND IMPROVES GLUCOSE TOLERANCE IN MICE
Pramfalk C; Ahmed O; Larsson L; Hardfeldt J; Pedrelli M; Vedin L; Steffensen K; Tellez M; Delbes A; Denis R; Luquet S; Eriksson M; Parini P
Meeting abstract: ATHEROSCLEROSIS. 2016;252:E62
REMNANT CHOLESTEROL REDUCTION BY EZETIMIBE AND SIMVASTATIN DOES NOT AFFECT BILIARY LIPID CONCENTRATION IN GALLSTONE PATIENTS
Eriksson M; Ahmed O; Gustafsson U; Littman K; Sahlin S; Pramfalk C; Parini P
Meeting abstract: ATHEROSCLEROSIS. 2016;252:E240
WORKSHOP 2.2: ADIPOSE TISSUE - LIVER AXIS. SOAT2 DEPLETION IMPROVES INSULIN SENSITIVITY AND HEPATIC STEATOSIS
Parini P; Pramfalk C; Ahmed O; Larsson L; Karpe F; Neville M; Eriksson M

Grants

Harnessing neural signals to treat fatty liver disease
Stiftelsen Professor Nanna Svartz fond
1 January 2024 - 31 December 2024
Neural regulation of the liver response to acute inflammation
Karolinska Institutet
1 January 2023 - 31 December 2024
Metabolism and Immunity in Critical Cardiovascular Diseases
Shandong University
1 January 2023 - 31 December 2027
Neural control of inflammation in liver disease
Stiftelsen Professor Nanna Svartz foundation
1 January 2023 - 31 December 2023
Neural control of inflammation in liver disease
Ruth och Richard Julins stiftelse
1 January 2023 - 31 December 2024
Neural control of inflammation in liver disease
Stiftelsen Lars Hiertas minne fond
1 January 2023
Metabolism and Immunity in Critical Cardiovascular Diseases
Shandong University
1 January 2023 - 31 December 2027
Metabolism and Immunity in Critical Cardiovascular Diseases
Shandong University
1 January 2023 - 31 December 2027

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2019

Articles

All other publications

Grants

Employments

Degrees and Education

News from KI

Events from KI