Osman Ahmed

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CV
Public outreach and news

Articles

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14):e2212476120
Cholinergic regulation of vascular endothelial function by human ChAT⁺ T cells
Tarnawski L; Shavva VS; Kort EJ; Zhuge Z; Nilsson I; Gallina AL; Martinez-Enguita D; Sahlgren BH; Weiland M; Caravaca AS; Schmidt S; Chen P; Abbas K; Wang F-H; Ahmed O; Eberhardson M; Farnert A; Weitzberg E; Gustafsson M; Kehr J; Malin SG; Hult H; Carlstrom M; Jovinge S; Olofsson PS
Article: BIOELECTRONIC MEDICINE. 2023;9(1):6
Hepatic stellate cell activation markers are regulated by the vagus nerve in systemic inflammation.
Ahmed O; Caravaca AS; Crespo M; Dai W; Liu T; Guo Q; Leiva M; Sabio G; Shavva VS; Malin SG; Olofsson PS
Journal article: ATHEROSCLEROSIS. 2022;355:20
Validation of network medicine interactomes: From patients to a human hepatocyte-like model
Grassi F; Dall'Olio D; Ahmed O; Sala C; Bersanelli M; Pramfalk C; Garagnani P; Petrillo E; Loscalzo J; Pedrelli M; Parini P
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):296-307
Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice
Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Hardfeldt J; Vedin L-L; Steffensen KR; Ryden M; Hodson L; Eriksson M; Parini P
Journal article: CIRCULATION. 2021;144(Suppl_1):a10013
Abstract 10013: PRDs Are Multifunctional Oral Inhibitors of PCSK9 and ACAT2
Paolo P; Ahmed O; Pedrelli M; Oshiro T; Pramfalk C; Eriksson M; Mejia E
Article: METHODS IN MOLECULAR BIOLOGY. 2020;2164:101-108
Enzymatic Quantification of Liver Lipids After Folch Extraction.
Minniti ME; Ahmed O; Pedrelli M
Article: DIGESTIVE AND LIVER DISEASE. 2019;51(7):1016-1022
Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice
Ahmed O; Pramfalk C; Pedrelli M; Olin M; Steffensen KR; Eriksson M; Parini P
Article: NATURE COMMUNICATIONS. 2019;10(1):1684
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα
Liang N; Damdimopoulos A; Goni S; Huang Z; Vedin L-L; Jakobsson T; Giudici M; Ahmed O; Pedrelli M; Barilla S; Alzaid F; Mendoza A; Schroder T; Kuiper R; Parini P; Hollenberg A; Lefebvre P; Francque S; Van Gaal L; Staels B; Venteclef N; Treuter E; Fan R
Article: BIOLOGY OF SEX DIFFERENCES. 2019;10(1):11
Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse
Gonzalez-Granillo M; Helguero LA; Alves E; Archer A; Savva C; Pedrelli M; Ahmed O; Li X; Domingues MR; Parini P; Gustafsson J-A; Korach-Andre M
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2018;7(24):e009876
Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients
Ahmed O; Littmann K; Gustafsson U; Pramfalk C; Oorni K; Larsson L; Minniti ME; Sahlin S; Camejo G; Parini P; Eriksson M
Article: ATHEROSCLEROSIS. 2018;275:246-255
Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption
Parini P; Melhuish TA; Wotton D; Larsson L; Ahmed O; Eriksson M; Pramfalk C
Article: PLOS NEGLECTED TROPICAL DISEASES. 2014;8(10):e3273
IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test
Bhattacharyya T; Ayandeh A; Falconar AK; Sundar S; El-Safi S; Gripenberg MA; Bowes DE; Thunissen C; Singh OP; Kumar R; Ahmed O; Eisa O; Saad A; Pereira SS; Boelaert M; Mertens P; Miles MA
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2014;306(5):E494-E502
Skeletal muscle as a target of LXR agonist after long-term treatment: focus on lipid homeostasis
Archer A; Laurencikiene J; Ahmed O; Steffensen KR; Parini P; Gustafsson J-A; Korach-Andre M
Article: PLOS NEGLECTED TROPICAL DISEASES. 2014;8(2):e2675
Significantly Lower Anti-Leishmania IgG Responses in Sudanese versus Indian Visceral Leishmaniasis
Bhattacharyya T; Bowes DE; El-Safi S; Sundar S; Falconar AK; Singh OP; Kumar R; Ahmed O; Boelaert M; Miles MA
Article: PLOS NEGLECTED TROPICAL DISEASES. 2010;4(8):e776
Diagnostic Accuracy of the Leishmania OligoC-TesT and NASBA-Oligochromatography for Diagnosis of Leishmaniasis in Sudan
Saad AA; Ahmed NG; Osman OS; Al-Basheer AA; Hamad A; Deborggraeve S; Buescher P; Schoone GJ; Schallig HD; Laurent T; Haleem A; Osman OF; Eltom AM; Elbashir MI; El-Safi S

All other publications

Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:s756-s757
Statins regulate PNPLA3 through a mechanism that requires SREBF2 in human liver cells
Ahmed O; Shavva VS; Dai W; Tarnawski L; Malin S; Franco-Cereceda A; Eriksson P; Bjorck H; Olofsson P
Preprint: BIORXIV. 2022
Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult
Hellberg S; Ahmed O; Zhang Y; Di Nunzio G; Björck HM; Francis R; Fagerberg L; Gisterå A; Zhang X; Metso J; Manfé V; Soto Y; Franco-Cereceda A; Eriksson P; Jauhiainen M; Olofsson PS; Malin SG
Conference publication: ATHEROSCLEROSIS. 2022;355:E51
VALIDATION OF NETWORK MEDICINE INTERACTOMES: FROM PATIENTS TO A HUMAN HEPATOCYTE-LIKE MODEL
Grassi F; Dall'Olio D; Ahmed O; Sala C; Bersanelli M; Pramfalk C; Garagnani P; Petrillo E; Loscalzo J; Pedrelli M; Parini P
Conference publication: ATHEROSCLEROSIS. 2021;331:E143-E144
HEPATIC TRANSCRIPTIONAL EFFECTS OF SIMVASTATIN AND THE POSSIBLE IMPACT ON COVID-19
Ahmed O; Mukarram AK; Pirazzini C; Marasco EE; Pedrelli M; Minniti ME; Gustafsson U; Pramfalk C; Binder CJ; Petrillo E; Garagnani PP; Daub CO; Eriksson M; Parini P
Thesis / dissertation: 2019
Role of cholesterol metabolism in hepatic steatosis and glucose tolerance
Ahmed, Osman Salih Osman
Meeting abstract: ATHEROSCLEROSIS. 2018;275:E234
SIMVASTATIN AND EZETIMIBE REDUCE PLASMA LIPOPROTEIN BINDING TO HUMAN ARTERIAL PROTEOGLYCANS IN GALLSTONE DISEASED PATIENTS
Littmann K; Ahmed O; Gustafsson U; Pramfalk C; Oorni K; Larsson L; Sahlin S; Camejo G; Parini P; Eriksson M
Meeting abstract: ATHEROSCLEROSIS. 2018;275:E25
GENETIC DEPLETION OF THE SOAT2 GENE DIMINISHES DIET-INDUCED HEPATIC STEATOSIS AND IMPROVES GLUCOSE TOLERANCE IN MICE
Pramfalk C; Ahmed O; Larsson L; Hardfeldt J; Pedrelli M; Vedin L; Steffensen K; Tellez M; Delbes A; Denis R; Luquet S; Eriksson M; Parini P
Meeting abstract: ATHEROSCLEROSIS. 2016;252:E62
REMNANT CHOLESTEROL REDUCTION BY EZETIMIBE AND SIMVASTATIN DOES NOT AFFECT BILIARY LIPID CONCENTRATION IN GALLSTONE PATIENTS
Eriksson M; Ahmed O; Gustafsson U; Littman K; Sahlin S; Pramfalk C; Parini P
Meeting abstract: ATHEROSCLEROSIS. 2016;252:E240
WORKSHOP 2.2: ADIPOSE TISSUE - LIVER AXIS. SOAT2 DEPLETION IMPROVES INSULIN SENSITIVITY AND HEPATIC STEATOSIS
Parini P; Pramfalk C; Ahmed O; Larsson L; Karpe F; Neville M; Eriksson M

Grants

Harnessing neural signals to treat fatty liver disease
Stiftelsen Professor Nanna Svartz fond
1 January 2024 - 31 December 2024
Neural regulation of the liver response to acute inflammation
Karolinska Institutet
1 January 2023 - 31 December 2024
Metabolism and Immunity in Critical Cardiovascular Diseases
Shandong University
1 January 2023 - 31 December 2027
Neural control of inflammation in liver disease
Stiftelsen Professor Nanna Svartz foundation
1 January 2023 - 31 December 2023
Neural control of inflammation in liver disease
Ruth och Richard Julins stiftelse
1 January 2023 - 31 December 2024
Neural control of inflammation in liver disease
Stiftelsen Lars Hiertas minne fond
1 January 2023
Metabolism and Immunity in Critical Cardiovascular Diseases
Shandong University
1 January 2023 - 31 December 2027
Metabolism and Immunity in Critical Cardiovascular Diseases
Shandong University
1 January 2023 - 31 December 2027

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2019

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