Markus Saarijärvi

Markus Saarijärvi

Affiliated to Research
Telephone: +46852483871
Visiting address: ANA 23, 14183 Huddinge
Postal address: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Omvårdnad Nilsson, 171 77 Stockholm

About me

  • I am an affiliated researcher at the Division of Nursing and currently hold a dual role as Nurse Researcher and Unit Manager at the Department of Cardiology, Danderyd Hospital, Stockholm. My research centers on the development, evaluation, and implementation of complex care interventions for individuals living with chronic conditions and their families. I serve as the principal investigator of the national research project Stepstones-Implement, which aims to implement and evaluate an evidence-based, person-centered transition program for young people with chronic illnesses as they move from pediatric to adult healthcare services.

Research

  • Research Profile
    My research focuses on complex interventions in healthcare, spanning from development to implementation. I am particularly interested in person-centered approaches, implementation science, and improving outcomes for vulnerable patient groups such as adolescents with chronic conditions and older adults undergoing cardiav surgery.

    Ongoing Research Projects

    Stepstones-Implement
    Principal Investigator – in collaboration with the University of Gothenburg and six university hospitals in Sweden
    The aim of Stepstones-Implement is to implement an effective and sustainable person-centered transition program for adolescents with heart disease and other chronic conditions. The project has three core objectives:

    1. Identify facilitators and barriers to implementing a person-centered transition program at six Swedish university hospitals offering specialized care for youth with heart defects.

    2. Implement the program using predefined strategies and evaluate its effects on patient-reported outcomes (e.g., empowerment, transition preparedness, quality of life, and care experience) and healthcare professionals’ attitudes toward transitional care.

    3. Assess the role of specially trained local facilitators in promoting implementation and long-term sustainability.

    Stepstones-Neuropsychiatric conditions

    Principal Investigator – in collaboration with the University of Gothenburg and Västra Götaland Region

    The aim of the project is to adapt and co-design a person-centered transition program for adolescents with neuropsychiatric conditions in transition to adulthood and adult care. The project has two objectives:

    1. To explore how the STEPSTONES transition program can be adapted by interviewing adolescents, parents and healthcare professionals
    2. To co-design and adapt the program using experience-based co-design 

    Digi-Stepstones
    Co-researcher – in collaboration with the University of Gothenburg and Västra Götaland Region
    Digi-STEPSTONES aims to develop and evaluate a digital, person-centered transition program to support adolescents with chronic conditions in becoming active participants in their health and care as they transition to adulthood. The intervention builds on the original Stepstones program, and three studies are currently planned under this initiative.

    PeriBrainCare – Postoperative Cognitive Recovery
    Co-researcher – in collaboration with Karolinska Institutet, Västra Götaland Region, and Stockholm Region
    This project investigates postoperative neurocognitive recovery in older adults undergoing surgery. It employs a broad methodological approach, including analog and digital neurocognitive assessments, biomarkers, patient and caregiver experiences, symptom tracking, and longitudinal follow-up to understand recovery trajectories and contributing factors.

    Trach-Inspire
    Co-researcher – in collaboration with Karolinska Institutet, Umeå University, and two university hospitals (Skåne and Umeå)
    TrachIspire aims to implement and evaluate the clinical outcomes and implementation process of early interprofessional use of speaking valves for tracheotomized, mechanically ventilated patients in intensive care units in Sweden.

    Research Group Affiliations

    • Perioperative Care, Karolinska Institutet
    • Transitions of Care in Health and Healthcare, University of Gothenburg

    Research Funding

    • Forte Starting Grant (2024–2026)
    • Swedish Heart-Lung Foundation Postdoctoral Grant (2024–2025)
    • Co-applicant on several successful grants from the Swedish Research Council, Forte, and the Swedish Childhood Cancer Foundation

    Other Achievements and Appointments

    • Associate Editor for the European Journal of Cardiovascular Nursing, with a focus on knowledge implementation
    • Recipient of the journal’s Most Cited Article award in 2022

Teaching

  • My teaching primarily focuses on scientific methodology within the bachelor's and master's programs in Nursing. I am also actively involved in supervising degree projects at the advanced level. I am currently supervising 4 PhD students.

Articles

All other publications

Grants

  • Swedish Research Council for Health Working Life and Welfare
    1 February 2025 - 31 January 2028
    Young people with long-term conditions need to be transferred from pediatric to adult healthcare to ensure continuous medical follow-up and health throughout their lives. Transition programs have been developed to empower young people to take charge of their health and care as they transition into adulthood. These programs have the potential to reduce the risk of complications and positively impact overall health and quality of life. Internationally, the interest in this research field has increased in the past decade. In Sweden, transition programs have been evaluated through several research projects that combine various methodologies and have involved different healthcare settings.   Considering the ongoing developments in this field, as well as the strong interest from healthcare providers and the research community, the need for a national research network for transitional care in Sweden has become evident. The purpose of the research network is to strengthen research in this area, coordinate research initiatives, and implement research findings in the surrounding community. The network will not only work closely with researchers, but will include the target groups, i.e., young people with long-term conditions, their parents, healthcare professionals and representatives from interest and patient organizations, in the planned activities. This close collaboration  will ensure implementation strategies and future research projects are aligned with the needs of the population.  The steering committee (i.e. the researchers in this application) come from several Swedish universities and colleges, with different educational backgrounds and at different stages in their academic and research career. All members are involved in ongoing and planned research projects related to transitional care.
  • Swedish Research Council
    1 January 2025 - 31 December 2027
    The number of older people who undergo complex surgical procedures continues to rise. Old age is a significant risk factor for the development of postoperative neurocognitive decline which can lead to problems with performing daily activities and maintaining independence. The purpose of this study is to evaluate if the PeriBrainCare bundle has a positive effect on older people’s postoperative cognitive recovery after cardiac surgery. The aim is, to test if the PeriBrainCare bundle reduces postoperative cognitive complaints as reflected in postoperative symptoms and symptoms burden.This intervention will be nested in an ongoing trial performed by the PeriBrainCare group 2025-2029. A pragmatic stepwise cluster randomized study with data collection at two Thoracic clinics in Sweden, 220 participants ≥65 years old with a relative will be included. The PeriBrainCare bundle is based on international recommendations, guidelines, and research and contains three components: Preoperative patient education, a postoperative follow-up, and evaluating cognitive symptoms and complaints. Primary outcome is neurocognitive complaints, secondary outcomes are factors associated with cognitive decline, delirium, depression, functioning in daily life, frailty, and health economics. Patient´s and next of kin´s experiences will be assessed and evaluated. The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives.
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2024 - 31 December 2026
    Research problem and specific questionsAs adolescents with special healthcare needs must transition from pediatric to adult care, transition programs are needed and advocated. Studies evaluating the efficacy of these programs have been performed but no study has evaluated the effectiveness of a transition program in a real-life scenario. Thus, the purpose of this project is to implement an effective and sustainable person-centered transition program for adolescents with special healthcare needs in Swedish healthcare.Data and MethodThree studies will be performed
    (i) an implementation study using predefined implementation strategies at university hospitals in Sweden providing specialized care for adolescents with special healthcare needs and evaluating the effects in patient-reported outcomes (empowerment, transition readiness, disease-related knowledge and care experience) compared to a historical cohort from a previous randomized controlled trial
    (ii) a process evaluation of the implementation of the program and strategies used to facilitate implementation at the participating sites.
    and (iii) a needs assessment exploring the prerequisites for and adaptation of the transition program for adolescents with developmental and neuropsychiatric disabilities.Societal relevance and utilisationThe transition of care for adolescents with special healthcare needs must be more person-centered and tailored to the individual young persons and families needs. The project will provide evidence on the effectiveness of a person-centered transition program and which strategies are most successful in achieving effective and sustainable implementation of person-centered care interventions for adolescents in transition to adulthood. Furthermore, how transition programs can be adapted to the special needs of adolescents with disabilities is pivotal in providing equity in healthcare for diverse populations.Plan for project realisationThe transition program will be implemented and studied at specialized children´s wards at six university hospitals in Sweden during 2024.Study 1 and 2 will be carried out during 2024-2027 and study 3 during 2024-2025.
  • Swedish Research Council
    1 January 2024 - 31 December 2026
    The society is ageing and advantages in anesthesia and surgery allows more complex interventions in older persons. Old age is a significant risk factors for the development of postoperative neurocognitive decline characterized by a gradual decrease in performance in several cognitive domains such as memory, attention, information processing and executive functions, leading to problems with performing daily activities and maintaining independence and postoperative complications.  The purpose is to measure older persons’ postoperative neurocognitive function, to detect neurocognitive decline, and to identify risk factors and difficulties in daily living as well as explore close relatives’ experiences of it.A longitudinal observational mixed method study including 200 participants ≥65 years of age undergoing planned cardiac surgery in two different Thoracic surgery departments. Neurocognitive function will be assessed with a digital neurocognitive test battery, seven times over three years postoperatively. Risk/affected factors such as delirium, functional status, recovery, health literacy depression, unplanned healthcare visits and frailty as well as patients and close relative’s symptom burden experiences will be measured.The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives, by enhanced knowledge about postoperative cognitive decline/recovery and support to be implemented

Employments

  • Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024-2026
  • Lecturer, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2022-2024

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