Lars Tjernberg

Publications
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Public outreach and news

Articles

Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(7):3622
DEAD Box Helicase 24 Is Increased in the Brain in Alzheimer's Disease and App^N-LF Mice and Influences Presymptomatic Pathology
Axenhus M; Doeswijk T; Nilsson P; Matton A; Winblad B; Tjernberg L; Schedin-Weiss S
Article: BMC PUBLIC HEALTH. 2024;24(1):823
The impact of the COVID-19 pandemic on neurosurgery in the elderly population in Sweden
Axenhus M; Schedin-Weiss S; Tjernberg L; Winblad B
Article: ALZHEIMERS & DEMENTIA. 2023;19(7):3244-3249
A glycan epitope correlates with tau in serum and predicts progression to Alzheimer's disease in combination with APOE4 allele status
Zhou RZ; Vetrano DL; Grande G; Duell F; Jonsson L; Laukka EJ; Fredolini C; Winblad B; Tjernberg L; Schedin-Weiss S
Article: ALZHEIMERS RESEARCH & THERAPY. 2022;14(1):196
Aβ42 oligomer-specific antibody ALZ-201 reduces the neurotoxicity of Alzheimer's disease brain extracts
Sandberg A; Berenjeno-Correa E; Rodriguez RC; Axenhus M; Weiss SS; Batenburg K; Hoozemans JJM; Tjernberg LO; Scheper W
Article: GLYCOBIOLOGY. 2022;32(6):506-517
Lack of N-glycosylation increases amyloidogenic processing of the amyloid precursor protein
Lin T; van Husen LS; Yu Y; Tjernberg LO; Schedin-Weiss S
Article: BMC GERIATRICS. 2022;22(1):365
Changes in dementia diagnoses in Sweden during the COVID-19 pandemic
Axenhus M; Schedin-Weiss S; Tjernberg L; Wimo A; Eriksdotter M; Bucht G; Winblad B
Article: SCIENTIFIC DATA. 2021;8(1):312
Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis
Haytural H; Benfeitas R; Schedin-Weiss S; Bereczki E; Rezeli M; Unwin RD; Wang X; Dammer EB; Johnson ECB; Seyfried NT; Winblad B; Tijms BM; Visser PJ; Frykman S; Tjernberg LO
Article: CHEMBIOCHEM. 2021;22(22):3208-3213
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids
van Husen LS; Katsori A-M; Meineke B; Tjernberg LO; Schedin-Weiss S; Elsasser SJ
Article: JOURNAL OF NEUROCHEMISTRY. 2021;159(2):292-304
The N-glycan profile in cortex and hippocampus is altered in Alzheimer disease
Gaunitz S; Tjernberg LO; Schedin-Weiss S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2021;83(2):833-852
A Super-Resolved View of the Alzheimer's Disease-Related Amyloidogenic Pathway in Hippocampal Neurons
Yu Y; Gao Y; Winblad B; Tjernberg L; Weiss SS
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(9):4530
Live Cell FRET Imaging Reveals Amyloid β-Peptide Oligomerization in Hippocampal Neurons
Gao Y; Wennmalm S; Winblad B; Schedin-Weiss S; Tjernberg LO
Article: BRAIN COMMUNICATIONS. 2021;3(2):fcab079
Distinctive alteration of presynaptic proteins in the outer molecular layer of the dentate gyrus in Alzheimer's disease
Haytural H; Jorda-Siquier T; Winblad B; Mulle C; Tjernberg LO; Granholm A-C; Frykman S; Barthet G
Article: CURRENT ALZHEIMER RESEARCH. 2021;17(9):858-867
Huntingtin Levels arc Elevated in Hippocampal Post-Mortem Samples of Alzheimer's Disease Brain
Axenhus M; Winblad B; Tjernberg LO; Schedin-Weiss S
Article: FRONTIERS IN AGING NEUROSCIENCE. 2021;13:735334
Microdissected Pyramidal Cell Proteomics of Alzheimer Brain Reveals Alterations in Creatine Kinase B-Type, 14-3-3-γ, and Heat Shock Cognate 71
Sandebring-Matton A; Axenhus M; Bogdanovic N; Winblad B; Schedin-Weiss S; Nilsson P; Tjernberg LO
Article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 2020;1867(9):118737
Brain-derived neurotrophic factor (BDNF) promotes molecular polarization and differentiation of immature neuroblastoma cells into definitive neurons
Hromadkova L; Bezdekova D; Pala J; Schedin-Weiss S; Tjernberg LO; Hoschl C; Ovsepian SV
Article: FEBS JOURNAL. 2020;287(15):3221-3234
Glycan biomarkers for Alzheimer disease correlate with T-tau and P-tau in cerebrospinal fluid in subjective cognitive impairment
Schedin-Weiss S; Gaunitz S; Sui P; Chen Q; Haslam SM; Blennow K; Winblad B; Dell A; Tjernberg LO
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;75(1):321-335
Proteomics Time-Course Study of App Knock-In Mice Reveals Novel Presymptomatic Aβ₄₂-Induced Pathways to Alzheimer's Disease Pathology
Schedin-Weiss S; Nilsson P; Sandebring-Matton A; Axenhus M; Sekiguchi M; Saito T; Winblad B; Saido T; Tjernberg LO
Article: BMC NEUROSCIENCE. 2020;21(1):6
Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain
Lundgren JL; Vandermeulen L; Sandebring-Matton A; Ahmed S; Winblad B; Di Luca M; Tjernberg LO; Marcello E; Frykman S
Article: MOLECULAR & CELLULAR PROTEOMICS. 2020;19(1):128-141
The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease
Haytural H; Mermelekas G; Emre C; Nigam SM; Carroll SL; Winblad B; Bogdanovic N; Barthet G; Granholm A-C; Orre LM; Tjernberg LO; Frykman S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;72(2):537-548
Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products
van Husen LS; Schedin-Weiss S; Minh NT; Kazmi MA; Winblad B; Sakmar TP; Elsaesser SJ; Tjernberg LO
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;71(4):1163-1174
A Fragment of S38AA is a Novel Plasma Biomarker of Alzheimer's Disease
Hashimoto M; Yamazaki A; Ohno A; Kimura T; Winblad B; Tjernberg LO
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2019;95:86-95
APP depletion alters selective pre- and post-synaptic proteins
Martinsson I; Capetillo-Zarate E; Faideau M; Willen K; Esteras N; Frykman S; Tjernberg LO; Gouras GK
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2019;23(3):2103-2114
Conformation-specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen
Bonito-Oliva A; Schedin-Weiss S; Younesi SS; Tiiman A; Adura C; Paknejad N; Brendel M; Romin Y; Parchem RJ; Graff C; Vukojevic V; Tjernberg LO; Terenius L; Winblad B; Sakmar TP; Graham WV
Article: FRONTIERS IN AGING NEUROSCIENCE. 2019;11:273
Non-specific Detection of a Major Western Blotting Band in Human Brain Homogenates by a Multitude of Amyloid Precursor Protein Antibodies
Haytural H; Lundgren JL; Kose TB; Jorda-Siquier T; Kalcheva M; Ahmed MS; Winblad B; Sundstrom E; Barthet G; Tjernberg LO; Frykman S
Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):175-184
Cerebrospinal fluid from Alzheimer patients affects cell-mediated nerve growth factor production and cell survival in vitro
Eriksdotter M; Navarro-Oviedo M; Mitra S; Wahlberg L; Linderoth B; Tjernberg LO; Behbahani H
Article: LIFE SCIENCE ALLIANCE. 2018;1(3):e201800028
Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses
Yu Y; Jans DC; Winblad B; Tjernberg LO; Schedin-Weiss S
Article: PROTEIN SCIENCE. 2017;26(11):2312-2318
Systemic AA amyloidosis in the red fox (Vulpes vulpes)
Rising A; Cederlund E; Palmberg C; Uhlhorn H; Gaunitz S; Nordling K; Agren E; Ihse E; Westermark GT; Tjernberg L; Jornvall H; Johansson J; Westermark P
Article: ALZHEIMERS RESEARCH & THERAPY. 2017;9(1):57
Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels
Schedin-Weiss S; Inoue M; Hromadkova L; Teranishi Y; Yamamoto NG; Wiehager B; Bogdanovic N; Winblad B; Sandebring-Matton A; Frykman S; Tjernberg LO
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;483(1):352-358
Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2)
Frykman S; Inoue M; Ikeda A; Teranishi Y; Kihara T; Lundgren JL; Yamamoto NG; Bogdanovic N; Winblad B; Schedin-Weiss S; Tjernberg LO
Article: LANCET NEUROLOGY. 2016;15(5):455-532
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Winblad B; Amouyel P; Andrieu S; Ballard C; Brayne C; Brodaty H; Cedazo-Minguez A; Dubois B; Edvardsson D; Feldman H; Fratiglioni L; Frisoni GB; Gauthier S; Georges J; Graff C; Iqbal K; Jessen F; Johansson G; Jonsson L; Kivipelto M; Knapp M; Mangialasche F; Melis R; Nordberg A; Rikkert MO; Qiu C; Sakmar TP; Scheltens P; Schneider LS; Sperling R; Tjernberg LO; Waldemar G; Wimo A; Zetterberg H
Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2016;4:29
Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse
Schedin-Weiss S; Caesar I; Winblad B; Blom H; Tjernberg LO
Article: MOLECULAR NEUROBIOLOGY. 2015;52(3):1077-1092
Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells
Lucotte B; Tajhizi M; Alkhatib D; Samuelsson E-B; Wiehager B; Schedin-Weiss S; Sundstrom E; Winblad B; Tjernberg LO; Behbahani H
Article: ANALYTICAL CHEMISTRY. 2015;87(23):11700-11705
Highly Sensitive FRET-FCS Detects Amyloid β-Peptide Oligomers in Solution at Physiological Concentrations
Wennmalm S; Chmyrov V; Widengren J; Tjernberg L
Article: JOURNAL OF NEUROCHEMISTRY. 2015;135(3):606-615
ADAM10 and BACE1 are localized to synaptic vesicles
Lundgren JL; Ahmed S; Schedin-Weiss S; Gouras GK; Winblad B; Tjernberg LO; Frykman S
Article: PROTEOMICS. 2015;15(19):3349-3355
Loss of neprilysin alters protein expression in the brain of Alzheimer's disease model mice
Nilsson P; Loganathan K; Sekiguchi M; Winblad B; Iwata N; Saido TC; Tjernberg LO
Article: FEBS JOURNAL. 2015;282(17):3438-3451
Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Ab production without affecting Notch cleavage
Teranishi Y; Inoue M; Yamamoto NG; Kihara T; Wiehager B; Ishikawa T; Winblad B; Schedin-Weiss S; Frykman S; Tjernberg LO
Article: FEBS JOURNAL. 2015;282(14):2587-2599
Human brain proteins showing neuron-specific interactions with γ-secretase
Inoue M; Hur J-Y; Kihara T; Teranishi Y; Yamamoto NG; Ishikawa T; Wiehager B; Winblad B; Tjernberg LO; Schedin-Weiss S
Article: NEUROSCIENCE LETTERS. 2014;566:125-130
Activity-independent release of the amyloid β-peptide from rat brain nerve terminals
Lundgren JL; Ahmed S; Winblad B; Gouras GK; Tjernberg LO; Frykman S
Article: FEBS OPEN BIO. 2014;4:393-406
Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations
Wanngren J; Lara P; Ojemalm K; Maioli S; Moradi N; Chen L; Tjernberg LO; Lundkvist J; Nilsson I; Karlstrom H
Article: PLOS ONE. 2013;8(2):e55847
The Pathogenic Aβ43 Is Enriched in Familial and Sporadic Alzheimer Disease
Sandebring A; Welander H; Winblad B; Graff C; Tjernberg LO
Article: PLOS ONE. 2013;8(5):e63962
Visualizing Active Enzyme Complexes Using a Photoreactive Inhibitor for Proximity Ligation - Application on γ-Secretase
Schedin-Weiss S; Inoue M; Teranishi Y; Yamamoto NG; Karlstrom H; Winblad B; Tjernberg LO
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;424(3):476-481
Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production
Teranishi Y; Hur J-Y; Gu GJ; Kihara T; Ishikawa T; Nishimura T; Winblad B; Behbahani H; Kamali-Moghaddam M; Frykman S; Tjernberg LO
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(8):1686-1700
Analysis of microdissected neurons by 18O mass spectrometry reveals altered protein expression in Alzheimer's disease
Hashimoto M; Bogdanovic N; Nakagawa H; Volkmann I; Aoki M; Winblad B; Sakai J; Tjernberg LO
Article: NEUROCHEMISTRY INTERNATIONAL. 2012;61(1):108-118
Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing
Frykman S; Teranishi Y; Hur J-Y; Sandebring A; Yamamoto NG; Ankarcrona M; Nishimura T; Winblad B; Bogdanovic N; Schedin-Weiss S; Kihara T; Tjernberg LO
Article: NEUROBIOLOGY OF AGING. 2012;33(5):1010.e1-1010.e13
The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ
Philipson O; Lord A; Lalowski M; Soliymani R; Baumann M; Thyberg J; Bogdanovic N; Olofsson T; Tjernberg LO; Ingelsson M; Lannfelt L; Kalimo H; Nilsson LNG
Article: JOURNAL OF NEUROSCIENCE METHODS. 2012;205(2):364-367
A novel approach for Aβ_1-40 quantification using immuno-PCR
Hashimoto M; Aoki M; Winblad B; Tjernberg LO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(15):11991-12005
Identification of Novel γ-Secretase-associated Proteins in Detergent-resistant Membranes from Brain
Hur J-Y; Teranishi Y; Kihara T; Yamamoto NG; Inoue M; Hosia W; Hashimoto M; Winblad B; Frykman S; Tjernberg LO
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2011;15(10):2150-2163
γ-secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ₄₂/Aβ₄₀ ratio
Hedskog L; Petersen CAH; Svensson AI; Welander H; Tjernberg LO; Karlstrom H; Ankarcrona M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(36):31153-31158
Mutations in Nicastrin Protein Differentially Affect Amyloid β-Peptide Production and Notch Protein Processing
Pamren A; Wanngren J; Tjernberg LO; Winblad B; Bhat R; Naslund J; Karlstrom H
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(11):1202-1208
The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Aβ in different brain regions
Keller L; Welander H; Chiang H-H; Tjernberg LO; Nennesmo I; Wallin AK; Graff C
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2010;14(11):2675-2686
Affinity pulldown of γ-secretase and associated proteins from human and rat brain
Teranishi Y; Hur J-Y; Welander H; Franberg J; Aoki M; Winblad B; Frykman S; Tjernberg LO
Article: ACTA NEUROPATHOLOGICA. 2010;119(5):543-554
Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Aβ42 and Alzheimer's disease neuropathology
Hashimoto M; Bogdanovic N; Volkmann I; Aoki M; Winblad B; Tjernberg LO
Article: PLOS ONE. 2010;5(3):e9772
γ-Secretase Dependent Production of Intracellular Domains Is Reduced in Adult Compared to Embryonic Rat Brain Membranes
Franberg J; Karlstrom H; Winblad B; Tjernberg LO; Frykman S
Article: PLOS ONE. 2010;5(1):e8948
Synaptic and Endosomal Localization of Active γ-Secretase in Rat Brain
Frykman S; Hur J-Y; Franberg J; Aoki M; Winblad B; Nahalkova J; Behbahani H; Tjernberg LO
Article: NEUROCHEMISTRY INTERNATIONAL. 2010;56(1):67-76
CD147, a γ-secretase associated protein is upregulated in Alzheimer's disease brain and its cellular trafficking is affected by presenilin-2
Nahalkova J; Volkmann I; Aoki M; Winblad B; Bogdanovic N; Tjernberg LO; Behbahani H
Article: JOURNAL OF NEUROCHEMISTRY. 2009;110(2):697-706
Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains
Welander H; Franberg J; Graff C; Sundstrom E; Winblad B; Tjernberg LO
Article: NEUROREPORT. 2008;19(11):1085-1089
Amyloid β-peptide levels in laser capture microdissected cornu ammonis I pyramidal neurons of Alzheimer's brain
Aoki M; Volkmann I; Tjernberg LO; Winblad B; Bogdanovic N
Article: FEBS JOURNAL. 2008;275(6):1174-1187
Active γ-secretase is localized to detergent-resistant membranes in human brain
Hur J-Y; Welander H; Behbahani H; Aoki M; Franberg J; Winblad B; Frykman S; Tjernberg LO
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;361(4):822-828
Unwinding fibril formation of medin, the peptide of the most common form of human amyloid
Larsson A; Soderberg L; Westermark GT; Sletten K; Engstrom U; Tjernberg LO; Naslund J; Westermark P
Article: BIOCHEMISTRY. 2007;46(25):7647-7654
Rat brain γ-secretase activity is highly influenced by detergents
Franberg J; Welander H; Aoki M; Winblad B; Tjernberg LO; Frykman S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(39):29096-29104
Degradation of the amyloid β-protein by the novel mitochondrial peptidasome, PreP
Falkevall A; Alikhani N; Bhushan S; Pavlov PF; Busch K; Johnson KA; Eneqvist T; Tjernberg L; Ankarcrona M; Glaser E
Article: BIOCHEMISTRY. 2006;45(32):9849-9856
Analysis of single Alzheimer solid plaque cores by laser capture microscopy and nanoelectrospray/tandem mass spectrometry
Soderberg L; Bogdanovic N; Axelsson B; Winblad B; Naslund J; Tjernberg LO
Article: BIOCHEMISTRY. 2005;44(47):15602-15609
CLAC binds to aggregated Aβ and Aβ fragments, and attenuates fibril elongation
Kakuyama H; Söderberg L; Horigome K; Winblad B; Dahlqvist C; Näslund J; Tjernberg LO
Article: JOURNAL OF CELL BIOLOGY. 2005;171(1):87-98
Macroautophagy -: a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
Yu WH; Cuervo AM; Kumar A; Peterhoff CM; Schmidt SD; Lee JH; Mohan PS; Mercken M; Farmery MR; Tjernberg LO; Jiang Y; Duff K; Uchiyama Y; Nälund J; Mathews PM; Cataldo AM; Nixon RA
Article: FEBS JOURNAL. 2005;272(9):2231-2236
Collagenous Alzheimer amyloid plaque component assembles amyloid fibrils into protease resistant aggregates
Söderberg L; Dahlqvist C; Kakuyama H; Thyberg J; Ito A; Winblad B; Näslund J; Tjernberg LO
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(2):1007-1015
Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid β-peptide-binding site
Söderberg L; Kakuyama H; Möller A; Ito A; Winblad B; Tjernberg LO; Näslund J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(49):51654-51660
Nicastrin, presenilin, APH-1, and PEN-2 form active γ-secretase complexes in mitochondria
Hansson CA; Frykman S; Farmery MR; Tjernberg LO; Nilsberth C; Pursglove SE; Ito A; Winblad B; Cowburn RF; Thyberg J; Ankarcrona M
Article: BIOCHEMISTRY. 2004;43(16):4655-4661
Folding into a β-hairpin can prevent amyloid fibril formation
Hosia W; Bark N; Liepinsh E; Tjernberg A; Persson B; Hallén D; Thyberg J; Johansson J; Tjernberg L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(27):24277-24284
Partial purification and characterization of γ-secretase from post-mortem human brain
Farmery MR; Tjernberg LO; Pursglove SE; Bergman A; Winblad B; Näslund J
Article: NEUROSCIENCE LETTERS. 2003;337(2):111-113
No association between polymorphisms in the neprilysin promoter region and Swedish Alzheimer's disease patients
Lilius L; Forsell C; Axelman K; Winblad B; Graff C; Tjernberg L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(45):43243-43246
Charge attraction and β propensity are necessary for amyloid fibril formation from tetrapeptides
Tjernberg L; Hosia W; Bark N; Thyberg J; Johansson J
Article: BIOCHEMICAL JOURNAL. 2002;366(Pt 1):343-351
Assembling amyloid fibrils from designed structures containing a significant amyloid β-peptide fragment
Tjernberg LO; Tjernberg A; Bark N; Shi Y; Ruzsicska BP; Bu ZM; Thyberg J; Callaway DJE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(3):1673-1678
Controlling polymerization of β-amyloid and prion-derived peptides with synthetic small molecule ligands
Kuner P; Bohrmann B; Tjernberg LO; Näslund J; Huber G; Celenk S; Grüninger-Leitch F; Richards JG; Jakob-Roetne R; Kemp JA; Nordstedt C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999;96(15):8669-8674
Medin:: An integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid
Häggqvist B; Näslund J; Sletten K; Westermark GT; Mucchiano G; Tjernberg LO; Nordstedt C; Engström U; Westermark P
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(23):15990-15995
Endogenous proteins controlling amyloid β-peptide polymerization -: Possible implications for β-amyloid formation in the central nervous system and in peripheral tissues
Bohrmann B; Tjernberg L; Kuner P; Poli S; Levet-Trafit B; Näslund J; Richards G; Huber W; Döbeli H; Nordstedt C
Article: FEBS LETTERS. 1999;451(3):238-242
Binding of amyloid β-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB):: regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease
Oppermann UCT; Salim S; Tjernberg LO; Terenius L; Jörnvall H
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(18):12619-12625
A molecular model of Alzheimer amyloid β-peptide fibril formation
Tjernberg LO; Callaway DJE; Tjernberg A; Hahne S; Lilliehöök C; Terenius L; Thyberg J; Nordstedt C
Article: CHEMISTRY AND BIOLOGY. 1999;6(1):53-62
Amyloid β-peptide polymerization studied using fluorescence correlation spectroscopy
Tjernberg LO; Pramanik A; Björling S; Thyberg P; Thyberg J; Nordstedt C; Berndt KD; Terenius L; Rigler R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(19):12601-12605
Controlling amyloid beta-peptide fibril formation with protease-stable ligands
Tjernberg LO; Lilliehook C; Callaway DJE; Naslund J; Hahne S; Thyberg J; Terenius L; Nordstedt C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(3):1870-1875
Generation of Alzheimer amyloid beta peptide through nonspecific proteolysis
Tjernberg LO; Naslund J; Thyberg J; Gandy SE; Terenius L; Nordstedt C
Article: JOURNAL OF NEUROCHEMISTRY. 1996;67(1):294-301
High-resolution separation of amyloid beta-peptides: Structural variants present in Alzheimer's disease amyloid
Naslund J; Karlstrom AR; Tjernberg LO; Schierhorn A; Terenius L; Nordstedt C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(15):8545-8548
Arrest of beta-amyloid fibril formation by a pentapeptide ligand
Tjernberg LO; Naslund J; Lindqvist F; Johansson J; Karlstrom AR; Thyberg J; Terenius L; Nordstedt C
Article: NEURON. 1995;15(1):219-228
CHARACTERIZATION OF STABLE COMPLEXES INVOLVING APOLIPOPROTEIN-E AND THE AMYLOID-BETA PEPTIDE IN ALZHEIMERS-DISEASE BRAIN
NASLUND J; THYBERG J; TJERNBERG LO; WERNSTEDT C; KARLSTROM AR; BOGDANOVIC N; GANDY SE; LANNFELT L; TERENIUS L; NORDSTEDT C
Article: LAKARTIDNINGEN. 1995;92(18):1899-1900
[A breakthrough for research on Alzheimer disease. A model for drug testing].
Nordstedt C; Näslund J; Tjernberg LO; Terenius L
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All other publications

Review: BIOMEDICINES. 2021;9(7):801
Neuronal Trafficking of the Amyloid Precursor Protein-What Do We Really Know?
Lin T; Tjernberg LO; Schedin-Weiss S
Review: BIOMOLECULES. 2021;11(6):858
What Can N-glycomics and N-glycoproteomics of Cerebrospinal Fluid Tell Us about Alzheimer Disease?
Gaunitz S; Tjernberg LO; Schedin-Weiss S
Review: JOURNAL OF INTERNAL MEDICINE. 2016;280(2):153-163
Transmissible amyloid
Tjernberg LO; Rising A; Johansson J; Jaudzems K; Westermark P
Review: FEBS JOURNAL. 2014;281(1):46-62
The role of protein glycosylation in Alzheimer disease.
Schedin-Weiss S; Winblad B; Tjernberg LO
Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2010;14(4):741-757
Gene therapy in Alzheimer's disease - potential for disease modification
Nilsson P; Iwata N; Muramatsu S-I; Tjernberg LO; Winblad B; Saido TC
Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:s549
Localization of nicastrin/presenilin/APH-1/PEN-2 complexes to mitochondria
Hansson CA; Frykman S; Farmery MR; Tjernberg LO; Nilsberth C; Winblad B; Cowburn RF; Thyberg J; Ankarcrona M
Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:s148
Analysis of single Alzheimer plaque cores by laser-capture microscopy and nano-electrospray/tandem mass spectrometry
Tjernberg LO; Bogdanovic N; Axelsson B; Winblad B; Näslund J
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2004;61(3):326-335
Proteolytic generation and aggregation of peptides from transmembrane regions:: lung surfactant protein C and amyloid β-peptide
Johansson J; Weaver TE; Tjernberg LO
Thesis / dissertation: 1997
Molecular basis and pharmacological implications of Alzheimer amyloid ß-peptide fibril formation
Tjernberg, Lars
Review: LAKARTIDNINGEN. 1995;92(42):3881-3884
[Future drugs against aging? New research on molecular background of aging].
Nordstedt C; Näslund J; Tjernberg LO; Karlström A

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Senior Lecturer/Functional Manager, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2018-

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