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About me

I am a PhD student in medical science at the Aging Research Center, NVS, KI, with the focus on Geriatric epidemiology. 

I received my master degree in 2009 in Clinical Psychology at the University of Padua (Italy). Between 2010 and 2013, I collaborated on several research projects with the Italian National Research Council–Institute of Neuroscience, Aging Branch in Padua on the topics of the diabetes-related complications and cognitive function, diet and cognition in older people, quality of life in patients with knee surgery. I was registered as PhD student at NVS, Karolinska Institutet in May 2014 and, since December 2015, I am the chair of the PhD student Council at NVS. 

I am also a licensed psychologist since 2011, with training in neuropsychology in the Department of Neuroscience–Neurology I Operative Unit. While working with patients, I started to notice that those with diabetes had a different cognitive profile, so I wanted to learn more.

Education

  • Bachelor degree in "Cognitive psychology and psychobiology", University of Padua, Italy (2007)
  • Master degree in "Clinical psychology", University of Padua, Italy (2009)
  • Postgraduate diploma (II level) in "Forensic psychopathology and neuropsychology", University of Padua, Italy (2011)
  • Licensed psychologist, University of Padua, Italy (2011)

Research description

My research is on the impact of prediabetes and type 2 diabetes on different phases of cognitive aging (from being cognitively intact to the diagnosis of cognitive impairment and dementia), investigating the possible cerebral mechanisms (i.e., vascular and/or neurodegenerative) that may underlie cognitive decline in prediabetes and diabetes. Furthermore, in my research, I seek to address whether and to what extent diabetes-related factors (i.e., glycemic control, cardio- and cerebrovascular diseases), brain atrophy, vascular brain lesions, active lifestyle, and cognitive resreve can mediate the effects of prediabetes and diabetes on cognitive aging. In my PhD project, I used longitudinal data from three population-based observational studies: the Swedish National study on Aging and Care-Kungsholmen (SNAC-K), SNAC-K magnetic resonance imaging study (SNAC-K MRI), and the Swedish Adoption/Twin Study of Aging (SATSA).

Another research area I am interested in concerns the impact of nutrition and cognitive aging. I am currently collaborating with the EU-funded NU-AGE project, the first multicenter randomized controlled trial assessing the impact of a culturally adapted, individually tailored, whole Mediterrenean-like diet on age-related conditions such as cognitive and functional decline.  

Documents

Links

Publications

Cognitive Trajectories of Older Adults With Prediabetes and Diabetes: A Population-Based Cohort Study
Marseglia A, Dahl Aslan Ak, Fratiglioni L, Santoni G, Pedersen Nl, Xu W
The journals of gerontology. Series A, Biological sciences and medical sciences 2018;73(3):400-406

Consensus paper on the "executive summary of the international conference on Mediterranean diet and health: a lifelong approach" an Italian initiative supported by the Mediterranean Diet Foundation and the Menarini Foundation
Boccardi V, Calvani R, Limongi F, Marseglia A, Mason A, Noale M, et al
Nutrition (Burbank, Los Angeles County, Calif.) 2018;51-52():38-45

Diabetes in midlife and risk of cancer in late life: A nationwide Swedish twin study
Bao C, Pedersen Nl, Yang R, Marseglia A, Xu W, Wang Y, et al
International journal of cancer 2018;143(4):793-800

Effect of the NU-AGE Diet on Cognitive Functioning in Older Adults: A Randomized Controlled Trial
Marseglia A, Xu W, Fratiglioni L, Fabbri C, Berendsen Aam, Bialecka-debek A, et al
Frontiers in physiology 2018;9():349-

Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study
Dintica Cs, Rizzuto D, Marseglia A, Kalpouzos G, Welmer Ak, Wårdh I, et al
Neurobiology of aging 2018;67():23-30

Early Cognitive Deficits in Type 2 Diabetes: A Population-Based Study
Marseglia A, Fratiglioni L, Laukka Ej, Santoni G, Pedersen Nl, Bäckman L, et al
Journal of Alzheimer's disease : JAD 2016;53(3):1069-78

Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China
Ma F, Wu T, Zhao J, Han F, Marseglia A, Liu H, et al
The journals of gerontology. Series A, Biological sciences and medical sciences 2016;71(10):1376-83

Cognitive functioning among patients with diabetic foot
Marseglia A, Xu W, Rizzuto D, Ferrari C, Whisstock C, Brocco E, et al
Journal of diabetes and its complications 2014;28(6):863-8